Paola Fiorani
Affiliations: | Deparment of Biology Tor Vergata | National Research Council, Italy |
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"Paola Fiorani"
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Publications
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Ottaviani A, Pietrafesa D, Soren BC, et al. (2025) Unveiling the Mechanism of Action of Palmitic Acid, a Human Topoisomerase 1B Inhibitor from the Antarctic Sponge . International Journal of Molecular Sciences. 26 |
Ottaviani A, Iacovelli F, Welsch J, et al. (2022) Dimethylmyricacene: An In Vitro and In Silico Study of a Semisynthetic Non-Camptothecin Derivative Compound, Targeting Human DNA Topoisomerase 1B. Cells. 11 |
Ottaviani A, Welsch J, Agama K, et al. (2022) From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge . Journal of Enzyme Inhibition and Medicinal Chemistry. 37: 1404-1410 |
Soren BC, Babu Dasari J, Ottaviani A, et al. (2021) In Vitro and In Silico Characterization of an Antimalarial Compound with Antitumor Activity Targeting Human DNA Topoisomerase IB. International Journal of Molecular Sciences. 22 |
Ottaviani A, Iacovelli F, Fiorani P, et al. (2021) Natural Compounds as Therapeutic Agents: The Case of Human Topoisomerase IB. International Journal of Molecular Sciences. 22 |
Soren BC, Dasari JB, Ottaviani A, et al. (2020) Topoisomerase IB: a relaxing enzyme for stressed DNA. Cancer Drug Resistance (Alhambra, Calif.). 3: 18-25 |
Dasari JB, Soren BC, Ottaviani A, et al. (2020) Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Counterpart Strongly Impairs Enzyme Activity. Reports of Biochemistry & Molecular Biology. 8: 366-375 |
Wang Z, D'Annessa I, Tesauro C, et al. (2019) The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance. Archives of Biochemistry and Biophysics |
Wang Z, Ouyang H, Tesauro C, et al. (2018) Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate. Archives of Biochemistry and Biophysics |
Zuccaro L, Tesauro C, Kurkina T, et al. (2015) Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene. Acs Nano |