Madeline Luth
Affiliations: | 2016- | Pediatrics | University of California, San Diego, La Jolla, CA |
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"Madeline Luth"
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| Luth MR, Godinez-Macias KP, Chen D, et al. (2024) Systematic in vitro evolution in reveals key determinants of drug resistance. Science (New York, N.Y.). 386: eadk9893 |
| Xie SC, Wang Y, Morton CJ, et al. (2024) Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature Communications. 15: 937 |
| Collins JE, Lee JW, Rocamora F, et al. (2023) Antiplasmodial peptaibols act through membrane directed mechanisms. Cell Chemical Biology |
| Mandt REK, Luth MR, Tye MA, et al. (2023) Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance. Elife. 12 |
| Tilley L, Xie S, Wang Y, et al. (2023) Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Research Square |
| Kümpornsin K, Kochakarn T, Yeo T, et al. (2023) Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum. Nature Communications. 14: 3059 |
| Armstrong JF, Campo B, Alexander SPH, et al. (2023) Advances in Malaria Pharmacology and the online Guide to MALARIA PHARMACOLOGY: IUPHAR Review X. British Journal of Pharmacology |
| Bohmer MJ, Wang J, Istvan ES, et al. (2023) Human Polo-like Kinase Inhibitors as Antiplasmodials. Acs Infectious Diseases |
| Istvan ES, Guerra F, Abraham M, et al. (2023) Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science Translational Medicine. 15: eadc9249 |
| Arendse LB, Murithi JM, Qahash T, et al. (2022) The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple kinases and life cycle stages. Science Translational Medicine. 14: eabo7219 |