Parents
Sign in to add mentor| Carston R. Wagner | grad student | 2017 | UMN |
| Amit Choudhary | post-doc | Broad Institute of MIT and Harvard |
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Publications
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| Strom A, Shah R, Dolot R, et al. (2022) Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides. Biochemistry |
| Strom A, Shah R, Wagner CR. (2021) "Switching On" Enzyme Substrate Specificity Analysis with a Fluorescent Competitive Inhibitor. Biochemistry |
| Shah R, Peterson C, Strom A, et al. (2019) Inhibition of Hint1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chemical Neuroscience |
| Shah RM, Maize KM, West HT, et al. (2018) Structure and Functional Characterization of Human Histidine Triad Nucleotide Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia. Journal of Molecular Biology |
| Shah R, Zhou A, Wagner CR. (2017) Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain. Organic & Biomolecular Chemistry. 15: 10230-10237 |
| Maize KM, Shah R, Strom A, et al. (2017) A Crystal Structure-Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides. Molecular Pharmaceutics |
| Okon A, Matos de Souza MR, Shah R, et al. (2017) Anchimerically Activatable Antiviral ProTides. Acs Medicinal Chemistry Letters. 8: 958-962 |
| Shah R, Chou TF, Maize KM, et al. (2017) Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain. Biochemical and Biophysical Research Communications |
| Shah R, Maize KM, Zhou X, et al. (2017) Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1). Biochemistry |
| Shah R, Strom A, Zhou A, et al. (2016) Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. Acs Medicinal Chemistry Letters. 7: 780-4 |