Zhongyuan Kan

Affiliations: 
University of Pennsylvania Perelman School of Medicine 
Area:
Hydrogen Exchange Mass Spectrometry, Protein Biophysics
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"Zhongyuan Kan"

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S. Walter Englander research scientist 2006-2017 Penn
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Publications

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Shi F, Mendrola JM, Sheetz JB, et al. (2021) ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Reports. 37: 109834
Sweeny EA, Tariq A, Gurpinar E, et al. (2019) Structural and mechanistic insights into Hsp104 function revealed by synchrotron x-ray footprinting. The Journal of Biological Chemistry
Kan ZY, Ye X, Skinner JJ, et al. (2019) ExMS2: An Integrated Solution for Hydrogen-Deuterium Exchange Mass Spectrometry Data Analysis. Analytical Chemistry
Karch KR, Coradin M, Zandarashvili L, et al. (2018) Hydrogen-Deuterium Exchange Coupled to Top- and Middle-Down Mass Spectrometry Reveals Histone Tail Dynamics before and after Nucleosome Assembly. Structure (London, England : 1993)
Ye X, Mayne L, Kan ZY, et al. (2018) Folding of maltose binding protein outside of and in GroEL. Proceedings of the National Academy of Sciences of the United States of America
Englander SW, Mayne L, Kan ZY, et al. (2016) Protein Folding-How and Why: By Hydrogen Exchange, Fragment Separation, and Mass Spectrometry. Annual Review of Biophysics
Hu W, Kan ZY, Mayne L, et al. (2016) Cytochrome c folds through foldon-dependent native-like intermediates in an ordered pathway. Proceedings of the National Academy of Sciences of the United States of America
Casina VC, Hu W, Mao JH, et al. (2015) High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 9620-5
Bagchi A, Bessman NJ, Wu NZ, et al. (2014) Allosteric Regulation of the Epidermal Growth Factor Receptor Biophysical Journal. 106: 105a
Kan ZY, Walters BT, Mayne L, et al. (2013) Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis Proceedings of the National Academy of Sciences of the United States of America. 110: 16438-16443
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