Malcolm F. G. Stevens, PhD
Affiliations: | Cancer Research Laboratories, School of Pharmaceutical Sciences | University of Nottingham, Nottingham, England, United Kingdom |
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"Malcolm Stevens"Children
Sign in to add trainee| Geoffrey Wells | grad student | 1998 | Nottingham |
| Richard T Wheelhouse | post-doc | 1990-1996 | Nottingham |
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Publications
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| Patel A, Sharp SY, Hall K, et al. (2016) Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines. Organic & Biomolecular Chemistry |
| Zhang J, Hummersone M, Matthews CS, et al. (2015) N3-substituted temozolomide analogs overcome methylguanine-DNA methyltransferase and mismatch repair precipitating apoptotic and autophagic cancer cell death. Oncology. 88: 28-48 |
| Rizzo A, Iachettini S, Zizza P, et al. (2014) Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities. Journal of Experimental & Clinical Cancer Research : Cr. 33: 81 |
| Schwalbe C, Wells G, Stevens M. (2014) Influence of steric crowding on hydrogen bonding in anti-cancer quinols Acta Crystallographica Section a Foundations and Advances. 70: C561-C561 |
| Zhang J, Stevens MF, Bradshaw TD. (2012) Temozolomide: mechanisms of action, repair and resistance. Current Molecular Pharmacology. 5: 102-14 |
| Zhang J, Stevens MF, Hummersone M, et al. (2011) Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair. Oncology. 80: 195-207 |
| König J, Wyllie S, Wells G, et al. (2011) Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism. The Journal of Biological Chemistry. 286: 8523-33 |
| McCarroll AJ, Matthews CS, Wells G, et al. (2010) Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions. Organic & Biomolecular Chemistry. 8: 2078-84 |
| Zhang J, Stevens MF, Laughton CA, et al. (2010) Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications. Oncology. 78: 103-14 |
| Kadri H, Matthews CS, Bradshaw TD, et al. (2008) Synthesis and antitumour evaluation of novel 2-phenylbenzimidazoles. Journal of Enzyme Inhibition and Medicinal Chemistry. 23: 641-7 |