Bengt I. Samuelsson, Ph.D.
Affiliations: | 1967-1972 | Royal Veterinary College, Stockholm | |
| 1973- | Medical Chemistry | Karolinska Institute, Stockholm, Sweden |
Area:
endoperoxides, thromboxanes and the leukotrienesWebsite:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1982/samuelsson-bio.htmlGoogle:
"Bengt I. Samuelsson"Bio:
http://www.nasonline.org/member-directory/members/45923.html
The Nobel Prize in Physiology or Medicine 1982 was awarded jointly to Sune K. Bergström, Bengt I. Samuelsson and John R. Vane "for their discoveries concerning prostaglandins and related biologically active substances".
ACS Medicinal Chemistry Hall of Fame, 1982
Parents
Sign in to add mentor| Sune K. Bergström | grad student | 1960 | Karolinska |
| Elias James Corey | post-doc | 1961-1962 | Harvard |
Children
Sign in to add trainee| Lawrence J. Marnett | post-doc | 1975 | Karolinska |
| Charles N. Serhan | post-doc | 1982-1987 | Karolinska |
| Frank A. Fitzpatrick | research scientist | 1982-1983 | Karolinska |
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Publications
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| Shay AE, Nshimiyimana R, Samuelsson B, et al. (2021) Human leukocytes selectively convert 4,5-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Lukic A, Larssen P, Fauland A, et al. (2017) GM-CSF- and M-CSF-primed Mϕs present similar resolving but distinct inflammatory lipid mediator signatures. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
| Rådmark O, Werz O, Steinhilber D, et al. (2015) 5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease. Biochimica Et Biophysica Acta. 1851: 331-339 |
| Stsiapanava A, Olsson U, Wan M, et al. (2014) Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 111: 4227-32 |
| Rakonjac Ryge M, Tanabe M, Provost P, et al. (2014) A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity. Archives of Biochemistry and Biophysics. 545: 179-85 |
| Haas U, Raschperger E, Hamberg M, et al. (2011) Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development Proceedings of the National Academy of Sciences of the United States of America. 108: 20479-20484 |
| Esser J, Gehrmann U, Salvado MD, et al. (2011) Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors The Faseb Journal. 25: 1417-1427 |
| Gennaro AD, Wågsäter D, Mäyränpää MI, et al. (2010) Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm Proceedings of the National Academy of Sciences of the United States of America. 107: 21093-21097 |
| Rådmark O, Samuelsson B. (2010) Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. Biochemical and Biophysical Research Communications. 396: 105-110 |
| Rådmark O, Samuelsson B. (2009) 5-Lipoxygenase: mechanisms of regulation. Journal of Lipid Research. 50 |