Alina Tirla
Affiliations: | 2015-2019 | École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland |
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"Alina Tirla"Parents
Sign in to add mentor| Pablo Rivera-Fuentes | grad student | 2015-2019 | ETH Zürich |
| Seth B. Herzon | post-doc | Yale |
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Publications
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| Wernke KM, Tirla A, Xue M, et al. (2021) Probing Microbiome Genotoxicity: A Stable Colibactin Provides Insight into Structure-Activity Relationships and Facilitates Mechanism of Action Studies. Journal of the American Chemical Society |
| Tirla A, Wernke KM, Herzon SB. (2021) On the Stability and Spectroscopic Properties of 5-Hydroxyoxazole-4-carboxylic Acid Derivatives. Organic Letters |
| Nguyen J, Tirla A, Rivera-Fuentes P. (2021) Disruption of mitochondrial redox homeostasis by enzymatic activation of a trialkylphosphine probe. Organic & Biomolecular Chemistry |
| Williams PC, Wernke KM, Tirla A, et al. (2020) Employing chemical synthesis to study the structure and function of colibactin, a "dark matter" metabolite. Natural Product Reports |
| Wernke KM, Xue M, Tirla A, et al. (2020) Structure and bioactivity of colibactin. Bioorganic & Medicinal Chemistry Letters. 30: 127280 |
| Schaefer R, Monaco MR, Li M, et al. (2019) The Bioorthogonal Isonitrile-Chlorooxime Ligation. Journal of the American Chemical Society |
| Tirla A, Rivera-Fuentes P. (2019) Peptide Targeting of an Intracellular Receptor of the Secretory Pathway. Biochemistry. 58: 1184-1187 |
| Tirla A, Rivera-Fuentes P. (2018) Induction of Intracellular Reductive Stress with a Photoactivatable Phosphine Probe. Chimia. 72: 241-244 |
| Rivera-Fuentes P, Tirla A, Hansen M. (2017) Synthesis of Asparagusic Acid Modified Lysine and its Application in Solid-Phase Synthesis of Peptides with Enhanced Cellular Uptake Synlett. 29: 1289-1292 |
| Tirla A, Rivera-Fuentes P. (2016) Development of a Photoactivatable Phosphine Probe for Induction of Intracellular Reductive Stress with Single-Cell Precision. Angewandte Chemie (International Ed. in English). 55: 14709-14712 |