Stéphane P. Roche

Affiliations: 
2011- Florida Atlantic University, Boca Raton, FL, United States 
Area:
Synthetic Organic Chemistry, Reaction Design, Natural Product Synthesis, Biomimetic Synthesis, Chemical Biology and Drug Discovery
Website:
http://chemistry.fau.edu/directory/sroche.php
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"Stéphane Roche"
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Publications

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Scesa PD, Roche SP, West L. (2023) Enantioselective Synthesis of (+)-Providencin and Its Unexpected Regioisomer via a Biomimetic Norrish-Yang Cyclization from (-)-Bipinnatin E. Organic Letters
Scesa PD, West LM, Roche SP. (2021) Role of Macrocyclic Conformational Steering in a Kinetic Route toward Bielschowskysin. Journal of the American Chemical Society. 143: 7566-7577
Roche SP. (2021) Recent Advances in Oxa-6π Electrocyclization Reactivity for the Synthesis of Privileged Natural Product Scaffolds Organics. 2: 376-387
Shearer C, Desaunay O, Zorc S, et al. (2019) Intercepted-Knoevenagel condensation for the synthesis of unsymmetrical fused-tricyclic 4-pyrans. Tetrahedron. 75
Zaghouani M, Bögeholz LAK, Mercier E, et al. (2019) Total synthesis of (±)-fumimycin and analogues for biological evaluation as peptide deformylase inhibitors. Tetrahedron. 75: 3216-3230
Scesa P, Wangpaichitr M, Savaraj N, et al. (2017) A Kinetic Dearomatization Strategy for an Expedient Biomimetic Route to the Bielschowskysin Skeleton. Angewandte Chemie (International Ed. in English)
Santagata S, Mendillo ML, Tang YC, et al. (2013) Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state. Science (New York, N.Y.). 341: 1238303
Jeedimalla N, Johns J, Roche SP. (2013) Mechanistic investigation and implications of a sacrificial aniline for the tandem cascade synthesis of 4-aza-podophyllotoxin analogues Tetrahedron Letters. 54: 5845-5848
Lajkiewicz NJ, Roche SP, Gerard B, et al. (2012) Enantioselective photocycloaddition of 3-hydroxyflavones: total syntheses and absolute configuration assignments of (+)-ponapensin and (+)-elliptifoline. Journal of the American Chemical Society. 134: 13108-13
Rodrigo CM, Cencic R, Roche SP, et al. (2012) Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies. Journal of Medicinal Chemistry. 55: 558-62
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