Lisa-Maria Needham

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2014-2018 Chemistry University of Cambridge, Cambridge, England, United Kingdom 
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"Lisa-Maria Needham"
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Needham LM, Saavedra C, Rasch JK, et al. (2024) Label-free detection and profiling of individual solution-phase molecules. Nature. 629: 1062-1068
Needham LM, Saavedra C, Rasch JK, et al. (2023) Label-free observation of individual solution phase molecules. Biorxiv : the Preprint Server For Biology
Gorka F, Daly S, Pearson CM, et al. (2021) A Comparative Study of High-Contrast Fluorescence Lifetime Probes for Imaging Amyloid in Tissue. The Journal of Physical Chemistry. B
Vilalta A, Zhou Y, Sevalle J, et al. (2021) Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation. The Journal of Biological Chemistry. 100631
Samaan GN, Wyllie MK, Cizmic JM, et al. (2020) Single-molecule fluorescence detection of a tricyclic nucleoside analogue. Chemical Science. 12: 2623-2628
Needham LM, Weber J, Varela JA, et al. (2020) ThX - a next-generation probe for the early detection of amyloid aggregates. Chemical Science. 11: 4578-4583
Spark A, Kitching A, Esteban-Ferrer D, et al. (2020) vLUME: 3D virtual reality for single-molecule localization microscopy. Nature Methods
Needham LM, Weber J, Pearson CM, et al. (2020) A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores. The Journal of Physical Chemistry Letters
Di Antonio M, Ponjavic A, Radzevičius A, et al. (2020) Single-molecule visualization of DNA G-quadruplex formation in live cells. Nature Chemistry
Aprile FA, Sormanni P, Podpolny M, et al. (2020) Rational design of a conformation-specific antibody for the quantification of Aβ oligomers. Proceedings of the National Academy of Sciences of the United States of America
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