Hao Shao

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
heat shock protein 70 inhibitor
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"Hao Shao"
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Ferguson ID, Lin YT, Lam C, et al. (2022) Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma. Cell Chemical Biology
Shao H, Oltion K, Wu T, et al. (2020) Differential scanning fluorimetry (DSF) screen to identify inhibitors of Hsp60 protein-protein interactions. Organic & Biomolecular Chemistry
Bengoechea R, Findlay AR, Bhadra AK, et al. (2020) Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy. The Journal of Clinical Investigation
Wu PK, Hong SK, Chen W, et al. (2020) Mortalin (HSPA9) facilitates -mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. Science Signaling. 13
Shao H, Gestwicki JE. (2020) Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98. Bioorganic & Medicinal Chemistry Letters. 126954
Taylor IR, Assimon VA, Kuo SY, et al. (2020) Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells Chemical Science. 11: 1892-1904
Eftekharzadeh B, Banduseela VC, Chiesa G, et al. (2019) Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nature Communications. 10: 4605
Wang C, Scott SM, Sun S, et al. (2019) Individualized Management of Genetic Diversity in Niemann-Pick C1 through Modulation of the Hsp70 Chaperone System. Human Molecular Genetics
Eftekharzadeh B, Banduseela VC, Chiesa G, et al. (2019) Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nature Communications. 10: 3562
Taguwa S, Yeh MT, Rainbolt TK, et al. (2019) Zika Virus Dependence on Host Hsp70 Provides a Protective Strategy against Infection and Disease. Cell Reports. 26: 906-920.e3
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