Darin E. Jones
Affiliations: | University of Arkansas-Little Rock |
Area:
Organic Chemistry, Medicinal ChemistryGoogle:
"Darin Jones"Parents
Sign in to add mentorMichael Harmata | grad student | 1990-1996 | The University of Missouri |
James W. Janetka | research scientist | 2009-2011 | Washington University |
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Publications
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Brosey CA, Link TM, Shen R, et al. (2024) Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nature Chemical Biology |
Shrum SA, Nukala U, Shrimali S, et al. (2023) Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects. Antioxidants (Basel, Switzerland). 12 |
Syed A, Filandr F, Patterson-Fortin J, et al. (2023) Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity. Nucleic Acids Research |
Brosey CA, Shen R, Moiani D, et al. (2022) Applying HT-SAXS to chemical ligand screening. Methods in Enzymology. 678: 331-350 |
Mery DE, Compadre AJ, Ordóñez PE, et al. (2022) Analysis of Plant-Plant Interactions Reveals the Presence of Potent Antileukemic Compounds. Molecules (Basel, Switzerland). 27 |
Moiani D, Link TM, Brosey CA, et al. (2021) An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2. Methods in Enzymology. 661: 407-431 |
Ye Z, Xu S, Shi Y, et al. (2021) GRB2 enforces homology-directed repair initiation by MRE11. Science Advances. 7 |
Nguyen MT, Moiani D, Ahmed Z, et al. (2021) An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Progress in Biophysics and Molecular Biology |
Brosey CA, Houl JH, Katsonis P, et al. (2021) Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors. Progress in Biophysics and Molecular Biology |
Ordóñez PE, Mery DE, Sharma KK, et al. (2020) Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine. Molecules (Basel, Switzerland). 25 |