April L Lukowski
Affiliations: | University of California, San Diego, La Jolla, CA |
Area:
natural products, biosynthesis, biocatalysis, medicinal chemistryGoogle:
"April Lukowski"Parents
Sign in to add mentor| Alison Rae Narayan | grad student | 2015-2020 | University of Michigan |
| Bradley S. Moore | post-doc | 2020-2023 | UCSD |
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Publications
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| Phintha A, Lukowski AL, Chaiyen P. (2024) Unlocking the catalytic precision of ligand-controlled enzymatic halogenation. Proceedings of the National Academy of Sciences of the United States of America. 122: e2409479122 |
| Adak S, Ye N, Calderone LA, et al. (2024) A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. Nature Chemistry |
| Lukowski AL, Hubert FM, Ngo TE, et al. (2023) Enzymatic Halogenation of Terminal Alkynes. Journal of the American Chemical Society. 145: 18716-18721 |
| Adak S, Ye N, Calderone LA, et al. (2023) Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme. Biorxiv : the Preprint Server For Biology |
| Zetzsche LE, Yazarians JA, Chakrabarty S, et al. (2022) Biocatalytic oxidative cross-coupling reactions for biaryl bond formation. Nature. 603: 79-85 |
| Adak S, Lukowski AL, Schäfer RJB, et al. (2022) From Tryptophan to Toxin: Nature's Convergent Biosynthetic Strategy to Aetokthonotoxin. Journal of the American Chemical Society. 144: 2861-2866 |
| Purdy TN, Moore BS, Lukowski AL. (2022) Harnessing -Quinone Methides in Natural Product Biosynthesis and Biocatalysis. Journal of Natural Products |
| Liu J, Tian J, Perry C, et al. (2022) Design principles for site-selective hydroxylation by a Rieske oxygenase. Nature Communications. 13: 255 |
| Lukowski AL, Liu J, Bridwell-Rabb J, et al. (2020) Structural basis for divergent C-H hydroxylation selectivity in two Rieske oxygenases. Nature Communications. 11: 2991 |
| Lukowski AL, Mallik L, Hinze ME, et al. (2020) Substrate Promiscuity of a Paralytic Shellfish Toxin Amidinotransferase. Acs Chemical Biology |