Lisa Mydy

Affiliations: 
2010-2016 Department of Chemistry & Biochemistry University of Wisconsin-Milwaukee, Milwaukee, WI 
 2016-2019 Department of Structural Biology State University of New York, Buffalo, Buffalo, NY, United States 
 2020-2025 Department of Medicinal Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
 2025- Department of Biochemistry Purdue University, West Lafayette, IN, United States 
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"Lisa Mydy"

Parents

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Nicholas R. Silvaggi grad student 2010-2016 UW-Milwaukee (Physics Tree)
Andrew M. Gulick post-doc 2016-2019 SUNY Buffalo
Roland D. Kersten post-doc 2020-2025 University of Michigan
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Publications

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Gulick AM, Mydy LS, Patel KD. (2024) Kinetic analysis of the three-substrate reaction mechanism of an NRPS-independent siderophore (NIS) synthetase. Methods in Enzymology. 702: 1-19
Chekan JR, Mydy LS, Pasquale MA, et al. (2024) Plant peptides - redefining an area of ribosomally synthesized and post-translationally modified peptides. Natural Product Reports
Mydy LS, Hungerford J, Chigumba DN, et al. (2024) An intramolecular macrocyclase in plant ribosomal peptide biosynthesis. Nature Chemical Biology
Yang J, Banas VS, Patel KD, et al. (2022) An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD. The Journal of Biological Chemistry. 102166
Kersten RD, Mydy LS, Fallon TR, et al. (2022) Gene-Guided Discovery and Ribosomal Biosynthesis of Moroidin Peptides. Journal of the American Chemical Society
Mydy LS, Chigumba DN, Kersten RD. (2021) Plant Copper Metalloenzymes As Prospects for New Metabolism Involving Aromatic Compounds. Frontiers in Plant Science. 12: 692108
Chigumba DN, Mydy LS, de Waal F, et al. (2021) Discovery and biosynthesis of cyclic plant peptides via autocatalytic cyclases. Nature Chemical Biology. 18: 18-28
Mhashal AR, Romero-Rivera A, Mydy LS, et al. (2020) Modeling the Role of a Flexible Loop and Active Site Side Chains in Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase. Acs Catalysis. 10: 11253-11267
Mydy L, Bailey DC, Patel KD, et al. (2020) The Siderophore Synthetase IucA of the Aerobactin Biosynthetic Pathway Uses an Ordered Mechanism. Biochemistry
Mydy LS, Hoppe RW, Hagemann TM, et al. (2019) Correction to "Mechanistic Studies of the Aldolase-Dehydratase: Implications for Substrate and Reaction Specificity in the Acetoacetate Decarboxylase-like Superfamily". Biochemistry. 58: 5022
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