Spencer C. Peck, Ph.D.
Affiliations: | 2015- | Chemical Biology | Harvard University, Cambridge, MA, United States |
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"Spencer Peck"Parents
Sign in to add mentor| James Paddock Collman | research assistant | Stanford | |
| Wilfred A. van der Donk | grad student | 2009-2015 | UIUC |
| Emily Balskus | post-doc | 2015- | Harvard |
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Publications
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| Peck SC, Denger K, Burrichter A, et al. (2019) A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium . Proceedings of the National Academy of Sciences of the United States of America |
| Bougioukou DJ, Ting CP, Peck SC, et al. (2019) Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin. Organic & Biomolecular Chemistry |
| Born DA, Ulrich EC, Ju KS, et al. (2017) Structural basis for methylphosphonate biosynthesis. Science (New York, N.Y.). 358: 1336-1339 |
| Levin BJ, Huang YY, Peck SC, et al. (2017) A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline. Science (New York, N.Y.). 355 |
| Peck SC, Wang C, Dassama LM, et al. (2017) O-H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase. Journal of the American Chemical Society. 139: 2045-2052 |
| Peck SC, van der Donk WA. (2016) Go it alone: four-electron oxidations by mononuclear non-heme iron enzymes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry |
| Zhu H, Peck SC, Bonnot F, et al. (2015) Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species. Journal of the American Chemical Society |
| Peck SC, Chekan JR, Ulrich EC, et al. (2015) A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase. Journal of the American Chemical Society. 137: 3217-20 |
| Agarwal V, Peck SC, Chen JH, et al. (2014) Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation. Chemistry & Biology. 21: 125-35 |
| Wang C, Chang WC, Guo Y, et al. (2013) Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase. Science (New York, N.Y.). 342: 991-5 |