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Perry GS, Das M, Woon ECY. (2021) Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets. Journal of Medicinal Chemistry. 64: 16974-17003 |
Toh JDW, Sun L, Lau LZM, et al. (2015) A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N(6)-methyladenosine demethylase FTO. Chemical Science. 6: 112-122 |
Paine HA, Nathubhai A, Woon EC, et al. (2015) Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro. Bioorganic & Medicinal Chemistry |
Toh JDW, Sun L, Lau LZM, et al. (2015) A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO Chemical Science. 6: 112-122 |
Yeoh KK, Chan MC, Thalhammer A, et al. (2013) Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion. Organic & Biomolecular Chemistry. 11: 732-45 |
Rose NR, Woon EC, Tumber A, et al. (2012) Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. Journal of Medicinal Chemistry. 55: 6639-43 |
Demetriades M, Leung IK, Chowdhury R, et al. (2012) Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors. Angewandte Chemie (International Ed. in English). 51: 6672-5 |
Woon EC, Demetriades M, Bagg EA, et al. (2012) Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase. Journal of Medicinal Chemistry. 55: 2173-84 |
Woon EC, Tumber A, Kawamura A, et al. (2012) Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases. Angewandte Chemie (International Ed. in English). 51: 1631-4 |
Woon EC, Zervosen A, Sauvage E, et al. (2011) Structure guided development of potent reversibly binding penicillin binding protein inhibitors. Acs Medicinal Chemistry Letters. 2: 219-23 |