Stefanie Brynn Bumpus
Affiliations: | 2010 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
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"Stefanie Bumpus"Parents
Sign in to add mentor| Neil L. Kelleher | grad student | 2010 | UIUC | |
| (Studies of new natural products and their biosynthesis spearheaded by high-resolution mass spectrometry.) | ||||
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Publications
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| Vagstad AL, Bumpus SB, Belecki K, et al. (2012) Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity. Journal of the American Chemical Society. 134: 6865-77 |
| Molohon KJ, Melby JO, Lee J, et al. (2011) Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics. Acs Chemical Biology. 6: 1307-13 |
| Hollenhorst MA, Bumpus SB, Matthews ML, et al. (2010) The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis. Journal of the American Chemical Society. 132: 15773-81 |
| Bumpus SB, Evans BS, Thomas PM, et al. (2009) A proteomics approach to discovering natural products and their biosynthetic pathways. Nature Biotechnology. 27: 951-6 |
| Calderone CT, Bumpus SB, Kelleher NL, et al. (2008) A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth. Proceedings of the National Academy of Sciences of the United States of America. 105: 12809-14 |
| Bumpus SB, Kelleher NL. (2008) Accessing natural product biosynthetic processes by mass spectrometry. Current Opinion in Chemical Biology. 12: 475-82 |
| Bumpus SB, Magarvey NA, Kelleher NL, et al. (2008) Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis. Journal of the American Chemical Society. 130: 11614-6 |
| Hansen DB, Bumpus SB, Aron ZD, et al. (2007) The loading module of mycosubtilin: an adenylation domain with fatty acid selectivity. Journal of the American Chemical Society. 129: 6366-7 |
| Yin J, Straight PD, Hrvatin S, et al. (2007) Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display. Chemistry & Biology. 14: 303-12 |
| Dorrestein PC, Bumpus SB, Calderone CT, et al. (2006) Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry. 45: 12756-66 |