| Year |
Citation |
Score |
| 2019 |
Liu F, Zhang Z, Levit A, Levring J, Touhara KK, Shoichet BK, Chen J. Structural identification of a hotspot on CFTR for potentiation. Science (New York, N.Y.). 364: 1184-1188. PMID 31221859 DOI: 10.2210/Pdb6O1V/Pdb |
0.513 |
|
| 2019 |
Lyu J, Wang S, Balius TE, Singh I, Levit A, Moroz YS, O'Meara MJ, Che T, Algaa E, Tolmachova K, Tolmachev AA, Shoichet BK, Roth BL, Irwin JJ. Ultra-large library docking for discovering new chemotypes. Nature. PMID 30728502 DOI: 10.1038/S41586-019-0917-9 |
0.575 |
|
| 2018 |
Xue AY, Di Pizio A, Levit A, Yarnitzky T, Penn O, Pupko T, Niv MY. Corrigendum: Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes. Frontiers in Molecular Biosciences. 5: 84. PMID 30255025 DOI: 10.3389/Fmolb.2018.00084 |
0.365 |
|
| 2018 |
Pottel J, Levit A, Korczynska M, Fischer M, Shoichet BK. The Recognition of Unrelated Ligands by Individual Proteins. Acs Chemical Biology. PMID 30095890 DOI: 10.1021/Acschembio.8B00443 |
0.617 |
|
| 2018 |
Nowak S, Di Pizio A, Levit A, Niv MY, Meyerhof W, Behrens M. Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14. Biochimica Et Biophysica Acta. PMID 30009876 DOI: 10.1016/J.Bbagen.2018.07.009 |
0.451 |
|
| 2018 |
Xue AY, Di Pizio A, Levit A, Yarnitzky T, Penn O, Pupko T, Niv MY. Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes. Frontiers in Molecular Biosciences. 5: 9. PMID 29552563 DOI: 10.3389/Fmolb.2018.00009 |
0.44 |
|
| 2018 |
Wang S, Che T, Levit A, Shoichet BK, Wacker D, Roth BL. Structure of the Ddopamine receptor bound to the atypical antipsychotic drug risperidone. Nature. PMID 29466326 DOI: 10.1038/Nature25758 |
0.614 |
|
| 2017 |
Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science (New York, N.Y.). 358: 381-386. PMID 29051383 DOI: 10.1126/Science.Aan5468 |
0.648 |
|
| 2017 |
Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell. 168: 377-389.e12. PMID 28129538 DOI: 10.1016/J.Cell.2016.12.033 |
0.599 |
|
| 2016 |
Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, et al. Structure-based discovery of opioid analgesics with reduced side effects. Nature. 1-6. PMID 27533032 DOI: 10.1038/Nature19112 |
0.497 |
|
| 2016 |
Di Pizio A, Levit A, Slutzki M, Behrens M, Karaman R, Niv MY. Comparing Class A GPCRs to bitter taste receptors: Structural motifs, ligand interactions and agonist-to-antagonist ratios. Methods in Cell Biology. 132: 401-27. PMID 26928553 DOI: 10.1016/bs.mcb.2015.10.005 |
0.419 |
|
| 2014 |
Levit A, Beuming T, Krilov G, Sherman W, Niv MY. Predicting GPCR promiscuity using binding site features Journal of Chemical Information and Modeling. 54: 184-194. PMID 24328091 DOI: 10.1021/Ci400552Z |
0.47 |
|
| 2014 |
Levit A, Nowak S, Peters M, Wiener A, Meyerhof W, Behrens M, Niv MY. The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1181-97. PMID 24285091 DOI: 10.1096/Fj.13-242594 |
0.456 |
|
| 2013 |
Born S, Levit A, Niv MY, Meyerhof W, Behrens M. The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 201-13. PMID 23283334 DOI: 10.1523/Jneurosci.3248-12.2013 |
0.467 |
|
| 2012 |
Levit A, Barak D, Behrens M, Meyerhof W, Niv MY. Homology model-assisted elucidation of binding sites in GPCRs. Methods in Molecular Biology (Clifton, N.J.). 914: 179-205. PMID 22976029 DOI: 10.1007/978-1-62703-023-6_11 |
0.494 |
|
| 2012 |
Wiener A, Shudler M, Levit A, Niv MY. BitterDB: a database of bitter compounds. Nucleic Acids Research. 40: D413-9. PMID 21940398 DOI: 10.1093/Nar/Gkr755 |
0.424 |
|
| 2011 |
Levit A, Yarnitzky T, Wiener A, Meidan R, Niv MY. Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs. Plos One. 6: e27990. PMID 22132188 DOI: 10.1371/Journal.Pone.0027990 |
0.491 |
|
| 2010 |
Hanna-Elias A, Manallack DT, Levit A, Nguyen W, Ayad F, Perera G, Shapiro M, Irving HR, Coupar IM, Iskander MN. Synthesis, testing and structure-activity studies on a library of 5-HT₄ ligands. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 6: 344-54. PMID 21175422 DOI: 10.2174/157340610793563965 |
0.35 |
|
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