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William R. Bishai - Publications

Affiliations: 
2004 Infectious Diseases Johns Hopkins University, Baltimore, MD 
Area:
molecular pathogenesis of tuberculosis
Website:
http://www.hopkinsmedicine.org/DOM/TB_Lab/faculty/bishai.html
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288 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Auld SC, Barczak AK, Bishai W, Coussens AK, Dewi IMW, Mitini-Nkhoma SC, Muefong C, Naidoo T, Pooran A, Stek C, Steyn AJC, Tezera L, Walker NF. Pathogenesis of Post-Tuberculosis Lung Disease: Defining Knowledge Gaps and Research Priorities at the 2 International Post-Tuberculosis Symposium. American Journal of Respiratory and Critical Care Medicine. PMID 39141569 DOI: 10.1164/rccm.202402-0374SO  0.331
2024 Shaku MT, Um PK, Ocius KL, Apostolos AJ, Pires MM, Bishai WR, Kana BD. A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice. Elife. 13. PMID 38639995 DOI: 10.7554/eLife.89157  0.345
2024 Yabaji SM, Zhernovkov V, Araveti PB, Lata S, Rukhlenko OS, Abdullatif SA, Alekseev Y, Ma Q, Dayama G, Lau NC, Bishai WR, Crossland NA, Campbell JD, Kholodenko BN, Gimelbrant AA, et al. Myc Dysregulation in Activated Macrophages Initiates Iron-Mediated Lipid Peroxidation that Fuels Type I Interferon and Compromises TB Resistance. Biorxiv : the Preprint Server For Biology. PMID 38496444 DOI: 10.1101/2024.03.05.583602  0.359
2023 Krug S, Gupta M, Kumar P, Feller L, Ihms EA, Kang BG, Srikrishna G, Dawson TM, Dawson VL, Bishai WR. Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide. Nature Communications. 14: 8161. PMID 38071218 DOI: 10.1038/s41467-023-43937-1  0.583
2023 Parveen S, Shen J, Lun S, Zhao L, Alt J, Koleske B, Leone RD, Rais R, Powell JD, Murphy JR, Slusher BS, Bishai WR. Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis. Nature Communications. 14: 7427. PMID 37973991 DOI: 10.1038/s41467-023-43304-0  0.662
2023 Koleske BN, Jacobs WR, Bishai WR. The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions. The Journal of Clinical Investigation. 133. PMID 37781921 DOI: 10.1172/JCI173156  0.328
2023 Bullen CK, Singh AK, Krug S, Lun S, Thakur P, Srikrishna G, Bishai WR. MDA5 RNA sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival. Jci Insight. PMID 37725440 DOI: 10.1172/jci.insight.166242  0.419
2023 Dabitao D, Bishai WR. Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes. Current Topics in Microbiology and Immunology. 441: 139-183. PMID 37695428 DOI: 10.1007/978-3-031-35139-6_6  0.34
2023 Baya B, Sanogo I, Kone M, Soumare D, Ouattara K, Somboro A, Wague M, Coulibaly N, Koloma I, Coulibaly M, Nantoume M, Perou M, Kone K, Coulibaly D, Boukary Diarra H, ... ... Bishai WR, et al. Relationship between patient sex and anatomical sites of extrapulmonary tuberculosis in Mali. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. 33: 100389. PMID 37637324 DOI: 10.1016/j.jctube.2023.100389  0.352
2023 Shaku MT, Um P, Ocius KL, Apostolos AJ, Pires MM, Bishai WR, Kana BD. A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice. Biorxiv : the Preprint Server For Biology. PMID 37205421 DOI: 10.1101/2023.05.03.539199  0.344
2023 Wen Y, Lun S, Jiao Y, Zhang W, Liu T, Yang F, Tang J, Bishai WR, Yu LF. Structure-directed identification of pyridine-2-methylamine derivatives as MmpL3 inhibitors for use as antitubercular agents. European Journal of Medicinal Chemistry. 255: 115351. PMID 37116266 DOI: 10.1016/j.ejmech.2023.115351  0.325
2023 Parveen S, Shen J, Lun S, Zhao L, Koleske B, Leone RD, Rais R, Powell JD, Murphy JR, Slusher BS, Bishai WR. Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against . Biorxiv : the Preprint Server For Biology. PMID 36865287 DOI: 10.1101/2023.02.23.529704  0.622
2023 Krug S, Prasad P, Xiao S, Lun S, Ruiz-Bedoya CA, Klunk M, Ordonez AA, Jain SK, Srikrishna G, Kramnik I, Bishai WR. Adjunctive Integrated Stress Response Inhibition Accelerates Tuberculosis Clearance in Mice. Mbio. e0349622. PMID 36853048 DOI: 10.1128/mbio.03496-22  0.387
2022 Ahmad N, Dugad S, Chauhan V, Ahmed S, Sharma K, Kachhap S, Zaidi R, Bishai WR, Lamichhane G, Kumar P. Allosteric cooperation in ß-lactam binding to a non-classical transpeptidase. Elife. 11. PMID 35475970 DOI: 10.7554/eLife.73055  0.73
2022 Dey RJ, Dey B, Harriff M, Canfield ET, Lewinsohn DM, Bishai WR. Augmentation of the Riboflavin-Biosynthetic Pathway Enhances Mucosa-Associated Invariant T (MAIT) Cell Activation and Diminishes Mycobacterium tuberculosis Virulence. Mbio. e0386521. PMID 35164552 DOI: 10.1128/mbio.03865-21  0.435
2021 Parveen S, Lun S, Urbanowski ME, Cardin M, Shen J, Murphy JR, Bishai WR. Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells and related cells using a diphtheria toxin-based fusion protein. The Journal of Infectious Diseases. PMID 33955457 DOI: 10.1093/infdis/jiab235  0.685
2021 Krug S, Parveen S, Bishai WR. Host-Directed Therapies: Modulating Inflammation to Treat Tuberculosis. Frontiers in Immunology. 12: 660916. PMID 33953722 DOI: 10.3389/fimmu.2021.660916  0.353
2021 Parveen S, Siddharth S, Cheung LS, Kumar A, Shen J, Murphy JR, Sharma D, Bishai WR. Therapeutic targeting with DABIL-4 depletes myeloid suppressor cells in 4T1 triple-negative breast cancer model. Molecular Oncology. PMID 33682324 DOI: 10.1002/1878-0261.12938  0.554
2021 Alsayed SSR, Lun S, Payne A, Bishai WR, Gunosewoyo H. Facile Synthesis and Antimycobacterial Activity of Isoniazid, Pyrazinamide and Ciprofloxacin Derivatives. Chemical Biology & Drug Design. PMID 33638304 DOI: 10.1111/cbdd.13836  0.346
2021 Lun S, Xiao S, Zhang W, Wang S, Gunosewoyo H, Yu LF, Bishai WR. Therapeutic potential of coumestan Pks13 inhibitors for tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 33558290 DOI: 10.1128/AAC.02190-20  0.311
2021 Zhang W, Liu LL, Lun S, Wang SS, Xiao S, Gunosewoyo H, Yang F, Tang J, Bishai WR, Yu LF. Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules. European Journal of Medicinal Chemistry. 213: 113202. PMID 33516983 DOI: 10.1016/j.ejmech.2021.113202  0.313
2020 Bhattacharya B, Xiao S, Chatterjee S, Urbanowski ME, Ordonez AA, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor JH, Ivanov AR, Yan BS, Kobzik L, ... ... Bishai WR, et al. The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. The Journal of Clinical Investigation. PMID 33301427 DOI: 10.1172/JCI130319  0.311
2020 Alsayed SSR, Lun S, Payne A, Bishai WR, Gunosewoyo H. Design, synthesis and antimycobacterial evaluation of novel adamantane and adamantanol analogues effective against drug-resistant tuberculosis. Bioorganic Chemistry. 104486. PMID 33276981 DOI: 10.1016/j.bioorg.2020.104486  0.429
2020 Alsayed SSR, Lun S, Luna G, Beh CC, Payne AD, Foster N, Bishai WR, Gunosewoyo H. Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents. Rsc Advances. 10: 7523-7540. PMID 33014349 DOI: 10.1039/C9Ra10663D  0.376
2020 Ignatius EH, Cohen KA, Bishai WR. Getting to the point in point-of-care diagnostics for tuberculosis. The Journal of Clinical Investigation. PMID 32986020 DOI: 10.1172/JCI142497  0.317
2020 Kone B, Somboro AM, Holl JL, Baya B, Togo AA, Sarro YDS, Diarra B, Kodio O, Murphy RL, Bishai W, Maiga M, Doumbia S. Exploring the usefulness of molecular epidemiology of tuberculosis in Africa: a systematic review. International Journal of Molecular Epidemiology and Genetics. 11: 1-15. PMID 32714498  0.319
2020 Onajole OK, Lun S, Yun YJ, Langue DY, Jaskula-Dybka M, Flores A, Frazier E, Scurry AC, Zavala A, Arreola KR, Pierzchalski B, Ayitou AJ, Bishai WR. Design, Synthesis and biological evaluation of novel imidazo[1,2-a]pyridinecarboxamides as potent anti-tuberculosis agents. Chemical Biology & Drug Design. PMID 32515129 DOI: 10.1111/Cbdd.13739  0.471
2020 Urbanowski ME, Ordonez AA, Ruiz-Bedoya CA, Jain SK, Bishai WR. Cavitary tuberculosis: the gateway of disease transmission. The Lancet. Infectious Diseases. 20: e117-e128. PMID 32482293 DOI: 10.1016/S1473-3099(20)30148-1  0.498
2020 Dorhoi A, Kotzé LA, Berzofsky JA, Sui Y, Gabrilovich DI, Garg A, Hafner R, Khader SA, Schaible UE, Kaufmann SH, Walzl G, Lutz MB, Mahon RN, Ostrand-Rosenberg S, Bishai W, et al. Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus. The Journal of Clinical Investigation. PMID 32420917 DOI: 10.1172/Jci136288  0.449
2020 Choudhary E, Bullen CK, Goel R, Singh AK, Praharaj M, Thakur P, Dhiman R, Bishai WR, Agarwal N. Relative and Quantitative Phosphoproteome Analysis of Macrophages in Response to Infection by Virulent and Avirulent Reveals a Distinct Role of the Cytosolic RNA Sensor RIG-I in Pathogenesis. Journal of Proteome Research. PMID 32407090 DOI: 10.1021/Acs.Jproteome.9B00895  0.379
2020 Namasivayam S, Diarra B, Diabate S, Sarro YDS, Kone A, Kone B, Tolofoudie M, Baya B, Diakite MT, Kodio O, Cohen K, Holl J, Achenbach CJ, Chatterjee S, Murphy RL, ... Bishai W, et al. Patients infected with Mycobacterium africanum versus Mycobacterium tuberculosis possess distinct intestinal microbiota. Plos Neglected Tropical Diseases. 14: e0008230. PMID 32401750 DOI: 10.1371/Journal.Pntd.0008230  0.521
2020 Schmitz KR, Handy EL, Compton CL, Gupta S, Bishai WR, Sauer RT, Sello JK. Acyldepsipeptide Antibiotics and a Bioactive Fragment Thereof Differentially Perturb Mycobacterium tuberculosis ClpXP1P2 Activity in vitro. Acs Chemical Biology. PMID 32083462 DOI: 10.1021/Acschembio.9B00454  0.479
2020 Vernon A, Bishai W. Modeling Treatment of Latent Tuberculosis: Shortening the Leap of Faith? American Journal of Respiratory and Critical Care Medicine. 201: 405-406. PMID 31765598 DOI: 10.1164/Rccm.201911-2160Ed  0.436
2019 Baya B, Diarra B, Diabate S, Kone B, Goita D, Sarro YDS, Cohen K, Holl JL, Achenbach CJ, Tolofoudie M, Georges Togo AC, Sanogo M, Kone A, Kodio O, Dabitao D, ... ... Bishai W, et al. Association of Infection with Slower Disease Progression Compared with in Malian Patients with Tuberculosis. The American Journal of Tropical Medicine and Hygiene. PMID 31733052 DOI: 10.4269/Ajtmh.19-0264  0.432
2019 Xiao S, Guo H, Weiner WS, Maddox C, Mao C, Gunosewoyo H, Pelly S, White EL, Rasmussen L, Schoenen FJ, Aubé J, Bishai WR, Lun S. Revisiting the β-lactams for tuberculosis therapy: a compound-compound synthetic lethality approach. Antimicrobial Agents and Chemotherapy. PMID 31427291 DOI: 10.1128/Aac.01319-19  0.352
2019 Kumar P, Kumar A, Parveen S, Murphy JR, Bishai W. Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy. Immunotherapy. PMID 31361167 DOI: 10.2217/Imt-2019-0060  0.678
2019 Parveen S, Bishai WR, Murphy JR. : Diphtheria Toxin, the Operon, and Its Regulation by Fe2 Activation of apo-DtxR. Microbiology Spectrum. 7. PMID 31267892 DOI: 10.1128/Microbiolspec.Gpp3-0063-2019  0.626
2019 Cao R, Islamoglu H, Teskey G, Gyurjian K, Abrahem R, Onajole OK, Lun S, Bishai W, Kozikowski AP, Fraix MP, Sathananthan A, Zhong L, Stec J, Venketaraman V. The preclinical candidate indole-2-carboxamide improves immune responses to Mycobacterium tuberculosis infection in healthy subjects and individuals with type 2 diabetes. International Microbiology : the Official Journal of the Spanish Society For Microbiology. PMID 31218537 DOI: 10.1007/S10123-019-00086-0  0.49
2019 Bishai WR, Timmins GS. Potential for breath test diagnosis of urease positive pathogens in lung infections. Journal of Breath Research. 13: 032002. PMID 31096193 DOI: 10.1088/1752-7163/Ab2225  0.351
2019 Lun S, Tasneen R, Chaira T, Stec J, Onajole OK, Yang TJ, Cooper CB, Mdluli K, Converse PJ, Nuermberger EL, Raj VS, Kozikowski A, Bishai WR. Advancing the therapeutic potential of indoleamides for tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 31010860 DOI: 10.1128/Aac.00343-19  0.398
2019 Dey RJ, Dey B, Singh AK, Praharaj M, Bishai W. BCG overexpressing an endogenous STING agonist provides enhanced protection against pulmonary tuberculosis. The Journal of Infectious Diseases. PMID 30901058 DOI: 10.1093/Infdis/Jiz116  0.342
2019 Zhang W, Lun S, Liu LL, Xiao S, Duan G, Gunosewoyo H, Yang F, Tang J, Bishai WR, Yu LF. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II. Journal of Medicinal Chemistry. PMID 30875203 DOI: 10.1021/acs.jmedchem.9b00010  0.31
2019 Cheung LS, Fu J, Kumar P, Kumar A, Urbanowski ME, Ihms EA, Parveen S, Bullen CK, Patrick GJ, Harrison R, Murphy JR, Pardoll DM, Bishai WR. Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718426 DOI: 10.1073/Pnas.1815087116  0.666
2019 Singh AK, Praharaj M, Joice GA, Yoshida T, Kates M, McConkey D, Bishai WR, Bivalacqua TJ. Abstract 3253: Next-gen STING-agonist like BCG confers enhanced immunogenicity and antitumor efficacy in vitro and in vivo Cancer Research. 79: 3253-3253. DOI: 10.1158/1538-7445.Am2019-3253  0.35
2018 Kone A, Diarra B, Cohen K, Diabate S, Kone B, Diakite MT, Diarra H, Sanogo M, Togo ACG, Sarro YDS, Baya B, Coulibaly N, Kodio O, Achenbach CJ, Murphy RL, ... ... Bishai WR, et al. Differential HLA Allele Frequency in M. africanum vs. M. tuberculosis in Mali. Hla. PMID 30516034 DOI: 10.1111/tan.13448  0.318
2018 Gupta S, Krug S, Pokkali S, Leanderson T, Isaacs JT, Srikrishna G, Bishai WR. Pharmacologic Exhaustion of Suppressor Cells with Tasquinimod Enhances Bacterial Clearance during TB. American Journal of Respiratory and Critical Care Medicine. PMID 30395729 DOI: 10.1164/Rccm.201805-0820Le  0.46
2018 Amaral EP, Riteau N, Moayeri M, Maier N, Mayer-Barber KD, Pereira RM, Lage SL, Kubler A, Bishai WR, D'Império-Lima MR, Sher A, Andrade BB. Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by in Infected Macrophages. Frontiers in Immunology. 9: 1427. PMID 29977244 DOI: 10.3389/Fimmu.2018.01427  0.33
2018 Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, Kübler A, Bishai WR, Elkington PT, Jain SK. Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology. The Journal of Infectious Diseases. PMID 29920600 DOI: 10.1093/Infdis/Jiy373  0.427
2018 Ihms EA, Urbanowski ME, Bishai WR. Diverse cavity types and evidence that mechanical action on the necrotic granuloma drives tuberculous cavitation. The American Journal of Pathology. PMID 29753789 DOI: 10.1016/J.Ajpath.2018.04.006  0.349
2018 Rifat D, Prideaux B, Savic RM, Urbanowski ME, Parsons TL, Luna B, Marzinke MA, Ordonez AA, DeMarco VP, Jain SK, Dartois V, Bishai WR, Dooley KE. Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data. Science Translational Medicine. 10. PMID 29618565 DOI: 10.1126/Scitranslmed.Aai7786  0.401
2018 Urbanowski ME, Ihms EA, Bigelow K, Kübler A, Elkington PT, Bishai WR. Repetitive Aerosol Exposure Promotes Cavitary Tuberculosis and Enables Screening for Targeted Inhibitors of Extensive Lung Destruction. The Journal of Infectious Diseases. PMID 29554286 DOI: 10.1093/Infdis/Jiy127  0.401
2018 Zhang W, Lun S, Wang SH, Jiang X, Yang F, Tang J, Manson AL, Earl AM, Gunosewoyo H, Bishai WR, Yu LF. Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors Against Mycobacterium Tuberculosis. Journal of Medicinal Chemistry. PMID 29328655 DOI: 10.1021/Acs.Jmedchem.7B01319  0.414
2017 Abel L, Fellay J, Haas DW, Schurr E, Srikrishna G, Urbanowski M, Chaturvedi N, Srinivasan S, Johnson DH, Bishai WR. Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives. The Lancet. Infectious Diseases. PMID 29111156 DOI: 10.1016/S1473-3099(17)30623-0  0.469
2017 Singh AK, Bishai WR. Partners in Crime: Phenolic Glycolipids and Macrophages. Trends in Molecular Medicine. PMID 28969977 DOI: 10.1016/J.Molmed.2017.09.003  0.324
2017 Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR. Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. The Journal of Infectious Diseases. 215: 1883-1887. PMID 28863467 DOI: 10.1093/Infdis/Jix208  0.711
2017 Bishai WR. Drug development: Locking down metabolism. Nature Chemical Biology. 13: 925-926. PMID 28820877 DOI: 10.1038/Nchembio.2452  0.398
2017 Kozikowski AP, Onajole OK, Stec J, Dupont C, Viljoen A, Richard M, Chaira T, Lun S, Bishai WR, Raj VS, Ordway D, Kremer L. Targeting Mycolic Acid Transport by Indole-2-carboxamides for the Treatment of Mycobacterium abscessus Infections. Journal of Medicinal Chemistry. PMID 28574259 DOI: 10.1021/Acs.Jmedchem.7B00582  0.405
2017 Rockwood N, Costa DL, Amaral EP, Du Bruyn E, Kubler A, Gil-Santana L, Fukutani KF, Scanga CA, Flynn JL, Jackson SH, Wilkinson KA, Bishai WR, Sher A, Wilkinson RJ, Andrade BB. Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes. Frontiers in Immunology. 8: 542. PMID 28553288 DOI: 10.3389/Fimmu.2017.00542  0.404
2017 Dey RJ, Dey B, Zheng Y, Cheung LS, Zhou J, Sayre D, Kumar P, Guo H, Lamichhane G, Sintim HO, Bishai WR. Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase. Nature Chemical Biology. 13: 210-217. PMID 28106876 DOI: 10.1038/Nchembio.2254  0.825
2017 Gupta S, Winglee K, Gallo R, Bishai WR. Bacterial subversion of cAMP signalling inhibits cathelicidin expression, which is required for innate resistance to Mycobacterium tuberculosis. The Journal of Pathology. PMID 28097645 DOI: 10.1002/Path.4878  0.506
2017 Manson AL, Cohen KA, Abeel T, Desjardins CA, Armstrong DT, Barry CE, Brand J, Chapman SB, Cho SN, Gabrielian A, Gomez J, Jodals AM, Joloba M, Jureen P, ... ... Bishai WR, et al. Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance. Nature Genetics. PMID 28092681 DOI: 10.1038/Ng.3767  0.699
2016 Ahidjo BA, Maiga MC, Ihms EA, Maiga M, Ordonez AA, Cheung LS, Beck S, Andrade BB, Jain S, Bishai WR. The antifibrotic drug pirfenidone promotes pulmonary cavitation and drug resistance in a mouse model of chronic tuberculosis. Jci Insight. 1: e86017. PMID 27699232 DOI: 10.1172/Jci.Insight.86017  0.463
2016 Singh DK, Dwivedi VP, Ranganathan A, Bishai WR, Kaer LV, Das G. Blockade of the Kv1.3 K+ channel enhances BCG vaccine efficacy by expanding central memory T lymphocytes. The Journal of Infectious Diseases. PMID 27571906 DOI: 10.1093/Infdis/Jiw395  0.351
2016 Maiga M, Cohen K, Baya B, Srikrishna G, Siddiqui S, Sanogo M, Somboro AM, Diarra B, Diallo MH, Mazumdar V, Yoder C, Orsega S, Belson M, Kassambara H, Goita D, ... ... Bishai WR, et al. Stool microbiome reveals diverse bacterial ureases as confounders of oral urea breath testing for Helicobacter pylori and Mycobacterium tuberculosis in Bamako, Mali. Journal of Breath Research. 10: 036012. PMID 27532494 DOI: 10.1088/1752-7155/10/3/036012  0.425
2016 Mvubu NE, Pillay B, Gamieldien J, Bishai W, Pillay M. Mycobacterium tuberculosis strains exhibit differential and strain-specific molecular signatures in pulmonary epithelial cells. Developmental and Comparative Immunology. PMID 27497873 DOI: 10.1016/J.Dci.2016.07.022  0.397
2016 Pelly S, Winglee K, Xia F, Stevens RL, Bishai WR, Lamichhane G. REMap: Operon map of M. tuberculosis based on RNA sequence data. Tuberculosis (Edinburgh, Scotland). 99: 70-80. PMID 27450008 DOI: 10.1016/J.Tube.2016.04.010  0.745
2016 Cohen KA, El-Hay T, Wyres KL, Weissbrod O, Munsamy V, Yanover C, Aharonov R, Shaham O, Conway TC, Goldschmidt Y, Bishai WR, Pym AS. Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics. Ebiomedicine. PMID 27333036 DOI: 10.1016/J.Ebiom.2016.05.041  0.399
2016 Stec J, Onajole OK, Lun S, Guo H, Merenbloom B, Vistoli G, Bishai WR, Kozikowski AP. Indole-2-carboxamide-Based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection. Journal of Medicinal Chemistry. PMID 27275668 DOI: 10.1021/Acs.Jmedchem.6B00415  0.428
2016 Ahidjo BA, Bishai WR. Phosphodiesterase inhibitors as adjunctive therapies for tuberculosis. Ebiomedicine. 4: 7-8. PMID 26981560 DOI: 10.1016/J.Ebiom.2016.02.016  0.382
2016 Mvubu NE, Pillay B, Gamieldien J, Bishai W, Pillay M. Canonical pathways, networks and transcriptional factor regulation by clinical strains of Mycobacterium tuberculosis in pulmonary alveolar epithelial cells. Tuberculosis (Edinburgh, Scotland). 97: 73-85. PMID 26980499 DOI: 10.1016/J.Tube.2015.12.002  0.357
2016 Winglee K, Manson McGuire A, Maiga M, Abeel T, Shea T, Desjardins CA, Diarra B, Baya B, Sanogo M, Diallo S, Earl AM, Bishai WR. Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction. Plos Neglected Tropical Diseases. 10: e0004332. PMID 26751217 DOI: 10.1371/Journal.Pntd.0004332  0.439
2016 Pelly S, Winglee K, Xia F, Stevens RL, Bishai WR, Lamichhane G. REMap: Operon map of M. tuberculosis based on RNA sequence data Tuberculosis. 99: 70-80. DOI: 10.1016/j.tube.2016.04.010  0.731
2015 Maiga M, Ahidjo BA, Maiga MC, Cheung L, Pelly S, Lun S, Bougoudogo F, Bishai WR. Erratum to "Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis" [EBioMedicine 2 (8), August 2015, 868-873]. Ebiomedicine. 2: 1834. PMID 26870809 DOI: 10.1016/J.Ebiom.2015.10.019  0.359
2015 Maiga MC, Ahmadou Ahidjo B, Maiga M, Bishai WR. Roflumilast, a type 4 phosphodiesterase inhibitor, shows promising adjunctive, host-directed therapeutic activity in a mouse model of tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 26438491 DOI: 10.1128/Aac.02145-15  0.462
2015 Maiga M, Ahidjo BA, Maiga MC, Cheung L, Pelly S, Lun S, Bougoudogo F, Bishai WR. Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis. Ebiomedicine. 2: 866-71. PMID 26425693 DOI: 10.1016/J.Ebiom.2015.07.014  0.498
2015 Cohen KA, Abeel T, Manson McGuire A, Desjardins CA, Munsamy V, Shea TP, Walker BJ, Bantubani N, Almeida DV, Alvarado L, Chapman SB, Mvelase NR, Duffy EY, Fitzgerald MG, Govender P, ... ... Bishai WR, et al. Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal. Plos Medicine. 12: e1001880. PMID 26418737 DOI: 10.1371/Journal.Pmed.1001880  0.501
2015 Kubler A, Larsson C, Luna B, Andrade BB, Amaral EP, Urbanowski M, Orandle M, Bock K, Ammerman NC, Cheung LS, Winglee K, Halushka M, Park JK, Sher A, Friedland JS, ... ... Bishai WR, et al. Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis. The Journal of Infectious Diseases. PMID 26416658 DOI: 10.1093/Infdis/Jiv458  0.355
2015 Winglee K, Lun S, Pieroni M, Kozikowski A, Bishai W. Mutation of Rv2887, a marR-like gene, confers Mycobacterium tuberculosis resistance to an imidazopyridine-based agent. Antimicrobial Agents and Chemotherapy. 59: 6873-81. PMID 26303802 DOI: 10.1128/AAC.01341-15  0.345
2015 Srikrishna G, Gupta S, Dooley KE, Bishai WR. Can the addition of verapamil to bedaquiline-containing regimens improve tuberculosis treatment outcomes? A novel approach to optimizing TB treatment. Future Microbiology. 10: 1257-60. PMID 26226503 DOI: 10.2217/Fmb.15.56  0.404
2015 Sullivan ZA, Wong EB, Ndung'u T, Kasprowicz VO, Bishai WR. Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV. Ebiomedicine. 2: 334-340. PMID 26114158 DOI: 10.1016/J.Ebiom.2015.03.005  0.372
2015 Pan SJ, Tapley A, Adamson J, Little T, Urbanowski M, Cohen K, Pym A, Almeida D, Dorasamy A, Layre E, Young DC, Singh R, Patel VB, Wallengren K, Ndung'u T, ... ... Bishai W, et al. Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules. The Journal of Infectious Diseases. PMID 26014799 DOI: 10.1093/Infdis/Jiv312  0.415
2015 Alyahya SA, Nolan ST, Smith CM, Bishai WR, Sadoff J, Lamichhane G. Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment. Plos One. 10: e0127907. PMID 25996375 DOI: 10.1371/Journal.Pone.0127907  0.769
2015 Young DC, Layre E, Pan SJ, Tapley A, Adamson J, Seshadri C, Wu Z, Buter J, Minnaard AJ, Coscolla M, Gagneux S, Copin R, Ernst JD, Bishai WR, Snider BB, et al. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection. Chemistry & Biology. 22: 516-26. PMID 25910243 DOI: 10.1016/J.Chembiol.2015.03.015  0.487
2015 Rahman MA, Sobia P, Dwivedi VP, Bhawsar A, Singh DK, Sharma P, Moodley P, Van Kaer L, Bishai WR, Das G. Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis. The Journal of Biological Chemistry. 290: 14407-17. PMID 25847237 DOI: 10.1074/Jbc.M115.653600  0.534
2015 Silva JR, Bishai WR, Govender T, Lamichhane G, Maguire GE, Kruger HG, Lameira J, Alves CN. Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 25762064 DOI: 10.1080/07391102.2015.1029000  0.73
2015 Dey B, Dey RJ, Cheung LS, Pokkali S, Guo H, Lee JH, Bishai WR. A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis. Nature Medicine. 21: 401-6. PMID 25730264 DOI: 10.1038/Nm.3813  0.486
2015 Hiruy H, Rogers Z, Mbowane C, Adamson J, Ngotho L, Karim F, Gumbo T, Bishai W, Jeena P. Subtherapeutic concentrations of first-line anti-TB drugs in South African children treated according to current guidelines: the PHATISA study. The Journal of Antimicrobial Chemotherapy. 70: 1115-23. PMID 25505005 DOI: 10.1093/Jac/Dku478  0.357
2015 Gupta S, Tyagi S, Bishai WR. Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model. Antimicrobial Agents and Chemotherapy. 59: 673-6. PMID 25331694 DOI: 10.1128/Aac.04019-14  0.41
2015 Kübler A, Luna B, Larsson C, Ammerman NC, Andrade BB, Orandle M, Bock KW, Xu Z, Bagci U, Molura DJ, Marshall J, Burns J, Winglee K, Ahidjo BA, Cheung LS, ... ... Bishai WR, et al. Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation. The Journal of Pathology. 235: 431-44. PMID 25186281 DOI: 10.1002/Path.4432  0.389
2015 Luna B, Kubler A, Larsson C, Foster B, Bagci U, Mollura DJ, Jain SK, Bishai WR. In vivo prediction of tuberculosis-associated cavity formation in rabbits. The Journal of Infectious Diseases. 211: 481-5. PMID 25117755 DOI: 10.1093/Infdis/Jiu449  0.303
2015 Winglee K, Lun S, Pieroni M, Kozikowski A, Bishai W. Mutation of Rv2887, a marR-Like gene, confers mycobacterium tuberculosis resistance to an imidazopyridine-based agent Antimicrobial Agents and Chemotherapy. 59: 6873-6881. DOI: 10.1128/Aac.01341-15  0.453
2015 Cohen KA, Abeel T, McGuire AM, Desjardins CA, Munsamy V, Shea TP, Walker BJ, Bantubani N, Almeida DV, Alvarado L, Chapman S, Mvelase NR, Duffy EY, Fitzgerald MG, Govender P, ... ... Bishai WR, et al. Evolution of extensively drug-resistant tuberculosis over four decades revealed by whole genome sequencing of Mycobacterium tuberculosis from KwaZulu-Natal, South Africa International Journal of Mycobacteriology. DOI: 10.1016/J.Ijmyco.2014.11.028  0.449
2014 Cohen KA, Bishai WR, Pym AS. Molecular Basis of Drug Resistance in Mycobacterium tuberculosis. Microbiology Spectrum. 2. PMID 26103975 DOI: 10.1128/Microbiolspec.Mgm2-0036-2013  0.426
2014 Almeida DV, Tyagi S, Li S, Wallengren K, Pym AS, Ammerman NC, Bishai WR, Grosset JH. Revisiting Anti-tuberculosis Activity of Pyrazinamide in Mice. Mycobacterial Diseases : Tuberculosis & Leprosy. 4: 145. PMID 25525563 DOI: 10.4172/2161-1068.1000145  0.462
2014 Dey B, Bishai WR. Crosstalk between Mycobacterium tuberculosis and the host cell. Seminars in Immunology. 26: 486-96. PMID 25303934 DOI: 10.1016/J.Smim.2014.09.002  0.449
2014 Choi SW, Maiga M, Maiga MC, Atudorei V, Sharp ZD, Bishai WR, Timmins GS. Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test. Nature Communications. 5: 4989. PMID 25247851 DOI: 10.1038/Ncomms5989  0.446
2014 Lun S, Miranda D, Kubler A, Guo H, Maiga MC, Winglee K, Pelly S, Bishai WR. Synthetic lethality reveals mechanisms of Mycobacterium tuberculosis resistance to β-lactams. Mbio. 5: e01767-14. PMID 25227469 DOI: 10.1128/Mbio.01767-14  0.472
2014 Stec J, Vilchèze C, Lun S, Perryman AL, Wang X, Freundlich JS, Bishai W, Jacobs WR, Kozikowski AP. Biological evaluation of potent triclosan-derived inhibitors of the enoyl-acyl carrier protein reductase InhA in drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. Chemmedchem. 9: 2528-37. PMID 25165007 DOI: 10.1002/Cmdc.201402255  0.381
2014 Winglee K, Eloe-Fadrosh E, Gupta S, Guo H, Fraser C, Bishai W. Aerosol Mycobacterium tuberculosis infection causes rapid loss of diversity in gut microbiota. Plos One. 9: e97048. PMID 24819223 DOI: 10.1371/Journal.Pone.0097048  0.476
2014 Maiga M, Choi SW, Atudorei V, Maiga MC, Sharp ZD, Bishai WR, Timmins GS. In vitro and in vivo studies of a rapid and selective breath test for tuberculosis based upon mycobacterial CO dehydrogenase. Mbio. 5: e00990. PMID 24736224 DOI: 10.1128/Mbio.00990-14  0.451
2014 Bhattacharya D, Dwivedi VP, Maiga M, Maiga M, Van Kaer L, Bishai WR, Das G. Small molecule-directed immunotherapy against recurrent infection by Mycobacterium tuberculosis. The Journal of Biological Chemistry. 289: 16508-15. PMID 24711459 DOI: 10.1074/Jbc.M114.558098  0.516
2014 Choudhary E, Bishai W, Agarwal N. Expression of a subset of heat stress induced genes of mycobacterium tuberculosis is regulated by 3′,5′-cyclic AMP Plos One. 9. PMID 24587015 DOI: 10.1371/Journal.Pone.0089759  0.335
2014 Schoonmaker MK, Bishai WR, Lamichhane G. Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams. Journal of Bacteriology. 196: 1394-402. PMID 24464457 DOI: 10.1128/Jb.01396-13  0.788
2014 Ordonez AA, Maiga M, Gupta S, Weinstein EA, Bishai WR, Jain SK. Novel adjunctive therapies for the treatment of tuberculosis. Current Molecular Medicine. 14: 385-95. PMID 24236454 DOI: 10.2174/1566524013666131118112431  0.484
2014 Foster B, Bagci U, Ziyue Xu, Dey B, Luna B, Bishai W, Jain S, Mollura DJ. Segmentation of PET images for computer-aided functional quantification of tuberculosis in small animal models. Ieee Transactions On Bio-Medical Engineering. 61: 711-24. PMID 24235292 DOI: 10.1109/Tbme.2013.2288258  0.313
2014 Gupta S, Cohen KA, Winglee K, Maiga M, Diarra B, Bishai WR. Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 574-6. PMID 24126586 DOI: 10.1128/Aac.01462-13  0.44
2014 Mvubu N, Pillay M, Gamieldien J, Bishai W, Pillay B. RNA-Seq reveals strain-specific immune gene expression by epithelial cells infected with Mycobacterium tuberculosis strains of varying pathogenicity International Journal of Infectious Diseases. 21: 6. DOI: 10.1016/J.Ijid.2014.03.418  0.361
2014 Mvubu NE, Gamieldien J, Bishai WR, Pillay B, Pillay M. 135 Cytokine. 70: 60. DOI: 10.1016/J.Cyto.2014.07.142  0.376
2013 Lun S, Guo H, Onajole OK, Pieroni M, Gunosewoyo H, Chen G, Tipparaju SK, Ammerman NC, Kozikowski AP, Bishai WR. Indoleamides are active against drug-resistant mycobacterium tuberculosis Nature Communications. 4. PMID 24352433 DOI: 10.1038/Ncomms3907  0.493
2013 Xu Z, Bagci U, Kubler A, Luna B, Jain S, Bishai WR, Mollura DJ. Computer-aided detection and quantification of cavitary tuberculosis from CT scans. Medical Physics. 40: 113701. PMID 24320475 DOI: 10.1118/1.4824979  0.392
2013 Seddon J, Kasprowicz V, Walker NF, Yuen HM, Sunpath H, Tezera L, Meintjes G, Wilkinson RJ, Bishai WR, Friedland JS, Elkington PT. Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis. The Journal of Infectious Diseases. 208: 1571-9. PMID 23922364 DOI: 10.1093/Infdis/Jit343  0.343
2013 Lun S, Guo H, Adamson J, Cisar JS, Davis TD, Chavadi SS, Warren JD, Quadri LE, Tan DS, Bishai WR. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrobial Agents and Chemotherapy. 57: 5138-40. PMID 23856770 DOI: 10.1128/Aac.00918-13  0.424
2013 Grosset JH, Tyagi S, Almeida DV, Converse PJ, Li SY, Ammerman NC, Bishai WR, Enarson D, Trébucq A. Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice. American Journal of Respiratory and Critical Care Medicine. 188: 608-12. PMID 23822735 DOI: 10.1164/Rccm.201304-0753Oc  0.415
2013 Gupta S, Tyagi S, Almeida DV, Maiga MC, Ammerman NC, Bishai WR. Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor. American Journal of Respiratory and Critical Care Medicine. 188: 600-7. PMID 23805786 DOI: 10.1164/Rccm.201304-0650Oc  0.427
2013 Bassett IM, Lun S, Bishai WR, Guo H, Kirman JR, Altaf M, O'Toole RF. Detection of inhibitors of phenotypically drug-tolerant Mycobacterium tuberculosis using an in vitro bactericidal screen. Journal of Microbiology (Seoul, Korea). 51: 651-8. PMID 23800952 DOI: 10.1007/S12275-013-3099-4  0.442
2013 Wong EB, Cohen KA, Bishai WR. Rising to the challenge: new therapies for tuberculosis. Trends in Microbiology. 21: 493-501. PMID 23764389 DOI: 10.1016/J.Tim.2013.05.002  0.407
2013 Maiga M, Ammerman NC, Maiga MC, Tounkara A, Siddiqui S, Polis M, Murphy R, Bishai WR. Adjuvant host-directed therapy with types 3 and 5 but not type 4 phosphodiesterase inhibitors shortens the duration of tuberculosis treatment. The Journal of Infectious Diseases. 208: 512-9. PMID 23641020 DOI: 10.1093/Infdis/Jit187  0.457
2013 Onajole OK, Pieroni M, Tipparaju SK, Lun S, Stec J, Chen G, Gunosewoyo H, Guo H, Ammerman NC, Bishai WR, Kozikowski AP. Preliminary structure - Activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains Journal of Medicinal Chemistry. 56: 4093-4103. PMID 23611124 DOI: 10.1021/Jm4003878  0.483
2013 Bishai W, Sullivan Z, Bloom BR, Andersen P. Bettering BCG: a tough task for a TB vaccine? Nature Medicine. 19: 410-1. PMID 23558628 DOI: 10.1038/Nm.3153  0.321
2013 Singh Y, Kaul V, Mehra A, Chatterjee S, Tousif S, Dwivedi VP, Suar M, Van Kaer L, Bishai WR, Das G. Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity. The Journal of Biological Chemistry. 288: 5056-61. PMID 23233675 DOI: 10.1074/Jbc.C112.439778  0.347
2012 Erdemli SB, Gupta R, Bishai WR, Lamichhane G, Amzel LM, Bianchet MA. Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2. Structure (London, England : 1993). 20: 2103-15. PMID 23103390 DOI: 10.1016/J.Str.2012.09.016  0.765
2012 Kaul V, Bhattacharya D, Singh Y, Van Kaer L, Peters-Golden M, Bishai WR, Das G. An important role of prostanoid receptor EP2 in host resistance to Mycobacterium tuberculosis infection in mice. The Journal of Infectious Diseases. 206: 1816-25. PMID 23033144 DOI: 10.1093/Infdis/Jis609  0.485
2012 Parthasarathy G, Lun S, Guo H, Ammerman NC, Geiman DE, Bishai WR. Rv2190c, an NlpC/P60 family protein, is required for full virulence of Mycobacterium tuberculosis. Plos One. 7: e43429. PMID 22952680 DOI: 10.1371/Journal.Pone.0043429  0.509
2012 Grosset J, Almeida D, Converse PJ, Tyagi S, Li SY, Ammerman NC, Pym AS, Wallengren K, Hafner R, Lalloo U, Swindells S, Bishai WR. Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide. Proceedings of the National Academy of Sciences of the United States of America. 109: 15001-5. PMID 22927424 DOI: 10.1073/Pnas.1203636109  0.418
2012 Larsson C, Luna B, Ammerman NC, Maiga M, Agarwal N, Bishai WR. Gene expression of Mycobacterium tuberculosis putative transcription factors whiB1-7 in redox environments. Plos One. 7: e37516. PMID 22829866 DOI: 10.1371/Journal.Pone.0037516  0.478
2012 Dwivedi VP, Bhattacharya D, Chatterjee S, Prasad DV, Chattopadhyay D, Van Kaer L, Bishai WR, Das G. Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells. The Journal of Biological Chemistry. 287: 33656-63. PMID 22810226 DOI: 10.1074/Jbc.M112.375154  0.438
2012 Maiga M, Abaza A, Bishai WR. Current tuberculosis diagnostic tools & role of urease breath test. The Indian Journal of Medical Research. 135: 731-6. PMID 22771606  0.352
2012 Grosset JH, Singer TG, Bishai WR. New drugs for the treatment of tuberculosis: hope and reality. The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 16: 1005-14. PMID 22762423 DOI: 10.5588/Ijtld.12.0277  0.431
2012 Skerry C, Harper J, Klunk M, Bishai WR, Jain SK. Adjunctive TNF inhibition with standard treatment enhances bacterial clearance in a murine model of necrotic TB granulomas. Plos One. 7: e39680. PMID 22761866 DOI: 10.1371/Journal.Pone.0039680  0.483
2012 Maiga M, Lun S, Guo H, Winglee K, Ammerman NC, Bishai WR. Risk of tuberculosis reactivation with tofacitinib (CP-690550). The Journal of Infectious Diseases. 205: 1705-8. PMID 22474037 DOI: 10.1093/Infdis/Jis269  0.472
2012 Pelly S, Bishai WR, Lamichhane G. A screen for non-coding RNA in Mycobacterium tuberculosis reveals a cAMP-responsive RNA that is expressed during infection. Gene. 500: 85-92. PMID 22446041 DOI: 10.1016/J.Gene.2012.03.044  0.779
2012 Lee JH, Ammerman NC, Nolan S, Geiman DE, Lun S, Guo H, Bishai WR. Isoniazid resistance without a loss of fitness in Mycobacterium tuberculosis. Nature Communications. 3: 753. PMID 22434196 DOI: 10.1038/Ncomms1724  0.523
2012 Maiga M, Agarwal N, Ammerman NC, Gupta R, Guo H, Maiga MC, Lun S, Bishai WR. Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model. Plos One. 7: e30749. PMID 22319585 DOI: 10.1371/Journal.Pone.0030749  0.487
2012 Lilienkampf A, Pieroni M, Franzblau SG, Bishai WR, Kozikowski AP. Derivatives of 3-isoxazolecarboxylic acid esters - a potent and selective compound class against replicating and nonreplicating Mycobacterium tuberculosis Current Topics in Medicinal Chemistry. 12: 729-734. PMID 22283815 DOI: 10.2174/156802612799984544  0.463
2012 Be NA, Bishai WR, Jain SK. Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. Bmc Microbiology. 12: 7. PMID 22243650 DOI: 10.1186/1471-2180-12-7  0.796
2012 Harper J, Skerry C, Davis SL, Tasneen R, Weir M, Kramnik I, Bishai WR, Pomper MG, Nuermberger EL, Jain SK. Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. The Journal of Infectious Diseases. 205: 595-602. PMID 22198962 DOI: 10.1093/Infdis/Jir786  0.492
2012 Chopra S, Matsuyama K, Tran T, Malerich JP, Wan B, Franzblau SG, Lun S, Guo H, Maiga MC, Bishai WR, Madrid PB. Evaluation of gyrase B as a drug target in Mycobacterium tuberculosis Journal of Antimicrobial Chemotherapy. 67: 415-421. PMID 22052686 DOI: 10.1093/Jac/Dkr449  0.436
2011 Olaleye O, Raghunand TR, Bhat S, Chong C, Gu P, Zhou J, Zhang Y, Bishai WR, Liu JO. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: S61-5. PMID 22115541 DOI: 10.1016/J.Tube.2011.10.012  0.526
2011 Jain P, Thaler DS, Maiga M, Timmins GS, Bishai WR, Hatfull GF, Larsen MH, Jacobs WR. Reporter phage and breath tests: emerging phenotypic assays for diagnosing active tuberculosis, antibiotic resistance, and treatment efficacy. The Journal of Infectious Diseases. 204: S1142-50. PMID 21996696 DOI: 10.1093/Infdis/Jir454  0.431
2011 Be NA, Klinkenberg LG, Bishai WR, Karakousis PC, Jain SK. Strain-dependent CNS dissemination in guinea pigs after Mycobacterium tuberculosis aerosol challenge. Tuberculosis (Edinburgh, Scotland). 91: 386-9. PMID 21831713 DOI: 10.1016/J.Tube.2011.07.003  0.793
2011 Maloney E, Lun S, Stankowska D, Guo H, Rajagoapalan M, Bishai WR, Madiraju MV. Alterations in phospholipid catabolism in Mycobacterium tuberculosis lysX mutant. Frontiers in Microbiology. 2: 19. PMID 21552395 DOI: 10.3389/Fmicb.2011.00019  0.351
2011 Jassal MS, Nedeltchev GG, Osborne J, Bishai WR. A modified scoring system to describe gross pathology in the rabbit model of tuberculosis. Bmc Microbiology. 11: 49. PMID 21375756 DOI: 10.1186/1471-2180-11-49  0.421
2011 Lamichhane G, Freundlich JS, Ekins S, Wickramaratne N, Nolan ST, Bishai WR. Essential metabolites of Mycobacterium tuberculosis and their mimics. Mbio. 2: e00301-10. PMID 21285434 DOI: 10.1128/Mbio.00301-10  0.781
2011 Pieroni M, Tipparaju SK, Lun S, Song Y, Sturm AW, Bishai WR, Kozikowski AP. Pyrido[1,2-a]benzimidazole-Based Agents Active Against Tuberculosis (TB), Multidrug-Resistant (MDR) TB and Extensively Drug-Resistant (XDR) TB Chemmedchem. 6: 334-342. PMID 21259445 DOI: 10.1002/Cmdc.201000490  0.51
2011 Festa RA, Jones MB, Butler-Wu S, Sinsimer D, Gerads R, Bishai WR, Peterson SN, Darwin KH. A novel copper-responsive regulon in Mycobacterium tuberculosis. Molecular Microbiology. 79: 133-48. PMID 21166899 DOI: 10.1111/J.1365-2958.2010.07431.X  0.379
2010 Bishai JD, Bishai WR, Bishai DM. Heightened vulnerability to MDR-TB epidemics after controlling drug-susceptible TB. Plos One. 5: e12843. PMID 20877639 DOI: 10.1371/Journal.Pone.0012843  0.497
2010 Klinkenberg LG, Lee JH, Bishai WR, Karakousis PC. The stringent response is required for full virulence of Mycobacterium tuberculosis in guinea pigs. The Journal of Infectious Diseases. 202: 1397-404. PMID 20863231 DOI: 10.1086/656524  0.48
2010 Nisa S, Blokpoel MC, Robertson BD, Tyndall JD, Lun S, Bishai WR, O'Toole R. Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery. The Journal of Antimicrobial Chemotherapy. 65: 2347-58. PMID 20810423 DOI: 10.1093/Jac/Dkq311  0.41
2010 Jassal MS, Nedeltchev GG, Lee JH, Choi SW, Atudorei V, Sharp ZD, Deretic V, Timmins GS, Bishai WR. 13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis. Plos One. 5: e12451. PMID 20805989 DOI: 10.1371/Journal.Pone.0012451  0.317
2010 Burns KE, Cerda-Maira FA, Wang T, Li H, Bishai WR, Darwin KH. "Depupylation" of prokaryotic ubiquitin-like protein from mycobacterial proteasome substrates. Molecular Cell. 39: 821-7. PMID 20705495 DOI: 10.1016/J.Molcel.2010.07.019  0.307
2010 Cerda-Maira FA, Pearce MJ, Fuortes M, Bishai WR, Hubbard SR, Darwin KH. Molecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosis. Molecular Microbiology. 77: 1123-35. PMID 20636328 DOI: 10.1111/J.1365-2958.2010.07276.X  0.392
2010 Converse PJ, Eisenach KD, Theus SA, Nuermberger EL, Tyagi S, Ly LH, Geiman DE, Guo H, Nolan ST, Akar NC, Klinkenberg LG, Gupta R, Lun S, Karakousis PC, Lamichhane G, ... ... Bishai WR, et al. The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models. Plos One. 5: e10289. PMID 20422019 DOI: 10.1371/Journal.Pone.0010289  0.79
2010 Zhang T, Bishai WR, Grosset JH, Nuermberger EL. Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. Antimicrobial Agents and Chemotherapy. 54: 2806-13. PMID 20421401 DOI: 10.1128/Aac.00400-10  0.412
2010 Jassal MS, Bishai WR. Epidemiology and challenges to the elimination of global tuberculosis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 50: S156-64. PMID 20397943 DOI: 10.1086/651486  0.443
2010 Gupta R, Lavollay M, Mainardi JL, Arthur M, Bishai WR, Lamichhane G. The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin. Nature Medicine. 16: 466-9. PMID 20305661 DOI: 10.1038/Nm.2120  0.795
2010 Olaleye O, Raghunand TR, Bhat S, He J, Tyagi S, Lamichhane G, Gu P, Zhou J, Zhang Y, Grosset J, Bishai WR, Liu JO. Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets. Chemistry & Biology. 17: 86-97. PMID 20142044 DOI: 10.1016/J.Chembiol.2009.12.014  0.8
2010 Agarwal N, Bishai WR. Microbiology. Subversion from the sidelines. Science (New York, N.Y.). 327: 417-8. PMID 20093460 DOI: 10.1126/Science.1185569  0.399
2010 Paige C, Bishai WR. Penitentiary or penthouse condo: the tuberculous granuloma from the microbe's point of view. Cellular Microbiology. 12: 301-9. PMID 20039878 DOI: 10.1111/J.1462-5822.2009.01424.X  0.499
2009 Olaleye OA, Bishai WR, Liu JO. Targeting the role of N-terminal methionine processing enzymes in Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 89: S55-9. PMID 20006307 DOI: 10.1016/S1472-9792(09)70013-7  0.5
2009 Davis SL, Nuermberger EL, Um PK, Vidal C, Jedynak B, Pomper MG, Bishai WR, Jain SK. Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment. Antimicrobial Agents and Chemotherapy. 53: 4879-84. PMID 19738022 DOI: 10.1128/Aac.00789-09  0.427
2009 Ahmad Z, Klinkenberg LG, Pinn ML, Fraig MM, Peloquin CA, Bishai WR, Nuermberger EL, Grosset JH, Karakousis PC. Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig. The Journal of Infectious Diseases. 200: 1136-43. PMID 19686043 DOI: 10.1086/605605  0.49
2009 Rifat D, Bishai WR, Karakousis PC. Phosphate depletion: a novel trigger for Mycobacterium tuberculosis persistence. The Journal of Infectious Diseases. 200: 1126-35. PMID 19686042 DOI: 10.1086/605700  0.43
2009 Maloney E, Stankowska D, Zhang J, Fol M, Cheng QJ, Lun S, Bishai WR, Rajagopalan M, Chatterjee D, Madiraju MV. The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides. Plos Pathogens. 5: e1000534. PMID 19649276 DOI: 10.1371/Journal.Ppat.1000534  0.388
2009 Agarwal N, Bishai WR. cAMP signaling in Mycobacterium tuberculosis. Indian Journal of Experimental Biology. 47: 393-400. PMID 19634702  0.332
2009 Davis SL, Be NA, Lamichhane G, Nimmagadda S, Pomper MG, Bishai WR, Jain SK. Bacterial thymidine kinase as a non-invasive imaging reporter for Mycobacterium tuberculosis in live animals. Plos One. 4: e6297. PMID 19606217 DOI: 10.1371/Journal.Pone.0006297  0.822
2009 Agarwal N, Lamichhane G, Gupta R, Nolan S, Bishai WR. Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase. Nature. 460: 98-102. PMID 19516256 DOI: 10.1038/Nature08123  0.793
2009 Conde MB, Efron A, Loredo C, De Souza GR, Graça NP, Cezar MC, Ram M, Chaudhary MA, Bishai WR, Kritski AL, Chaisson RE. Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial. Lancet (London, England). 373: 1183-9. PMID 19345831 DOI: 10.1016/S0140-6736(09)60333-0  0.438
2009 Be NA, Kim KS, Bishai WR, Jain SK. Pathogenesis of central nervous system tuberculosis. Current Molecular Medicine. 9: 94-9. PMID 19275620 DOI: 10.2174/156652409787581655  0.804
2009 Alahari A, Alibaud L, Trivelli X, Gupta R, Lamichhane G, Reynolds RC, Bishai WR, Guerardel Y, Kremer L. Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis. Molecular Microbiology. 71: 1263-77. PMID 19183278 DOI: 10.1111/J.1365-2958.2009.06604.X  0.794
2009 Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, Grosset JH, Jain SK, Lamichhane G, Manabe YC, McMurray DN, Nuermberger EL, Bishai WR. Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models. Infection and Immunity. 77: 1230-7. PMID 19103767 DOI: 10.1128/Iai.01117-08  0.779
2009 Nedeltchev GG, Raghunand TR, Jassal MS, Lun S, Cheng QJ, Bishai WR. Extrapulmonary dissemination of Mycobacterium bovis but not Mycobacterium tuberculosis in a bronchoscopic rabbit model of cavitary tuberculosis. Infection and Immunity. 77: 598-603. PMID 19064634 DOI: 10.1128/Iai.01132-08  0.504
2009 Jassal M, Bishai WR. Extensively drug-resistant tuberculosis. The Lancet. Infectious Diseases. 9: 19-30. PMID 18990610 DOI: 10.1016/S1473-3099(08)70260-3  0.482
2008 Be NA, Lamichhane G, Grosset J, Tyagi S, Cheng QJ, Kim KS, Bishai WR, Jain SK. Murine model to study the invasion and survival of Mycobacterium tuberculosis in the central nervous system. The Journal of Infectious Diseases. 198: 1520-8. PMID 18956986 DOI: 10.1086/592447  0.835
2008 Abdul-Majid KB, Ly LH, Converse PJ, Geiman DE, McMurray DN, Bishai WR. Altered cellular infiltration and cytokine levels during early Mycobacterium tuberculosis sigC mutant infection are associated with late-stage disease attenuation and milder immunopathology in mice. Bmc Microbiology. 8: 151. PMID 18798983 DOI: 10.1186/1471-2180-8-151  0.459
2008 Klinkenberg LG, Sutherland LA, Bishai WR, Karakousis PC. Metronidazole lacks activity against Mycobacterium tuberculosis in an in vivo hypoxic granuloma model of latency. The Journal of Infectious Diseases. 198: 275-83. PMID 18491971 DOI: 10.1086/589515  0.516
2008 Karakousis PC, Williams EP, Bishai WR. Altered expression of isoniazid-regulated genes in drug-treated dormant Mycobacterium tuberculosis. The Journal of Antimicrobial Chemotherapy. 61: 323-31. PMID 18156607 DOI: 10.1093/Jac/Dkm485  0.479
2008 Manabe YC, Kesavan AK, Lopez-Molina J, Hatem CL, Brooks M, Fujiwara R, Hochstein K, Pitt ML, Tufariello J, Chan J, McMurray DN, Bishai WR, Dannenberg AM, Mendez S. The aerosol rabbit model of TB latency, reactivation and immune reconstitution inflammatory syndrome. Tuberculosis (Edinburgh, Scotland). 88: 187-96. PMID 18068491 DOI: 10.1016/J.Tube.2007.10.006  0.458
2008 Lee JH, Geiman DE, Bishai WR. Role of stress response sigma factor SigG in Mycobacterium tuberculosis. Journal of Bacteriology. 190: 1128-33. PMID 18039768 DOI: 10.1128/Jb.00511-07  0.489
2008 Lee JH, Karakousis PC, Bishai WR. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. Journal of Bacteriology. 190: 699-707. PMID 17993538 DOI: 10.1128/Jb.01273-07  0.413
2008 Jain SK, Lamichhane G, Nimmagadda S, Pomper MG, Bishai WR. Antibiotic treatment of tuberculosis: Old problems, new solutions Microbe. 3: 285-292. DOI: 10.1128/Microbe.3.285.1  0.78
2007 Rosenthal IM, Zhang M, Williams KN, Peloquin CA, Tyagi S, Vernon AA, Bishai WR, Chaisson RE, Grosset JH, Nuermberger EL. Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model. Plos Medicine. 4: e344. PMID 18092886 DOI: 10.1371/Journal.Pmed.0040344  0.367
2007 Almeida D, Nuermberger E, Tyagi S, Bishai WR, Grosset J. In vivo validation of the mutant selection window hypothesis with moxifloxacin in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 51: 4261-6. PMID 17938193 DOI: 10.1128/Aac.01123-07  0.417
2007 Jain SK, Hernandez-Abanto SM, Cheng QJ, Singh P, Ly LH, Klinkenberg LG, Morrison NE, Converse PJ, Nuermberger E, Grosset J, McMurray DN, Karakousis PC, Lamichhane G, Bishai WR. Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice. The Journal of Infectious Diseases. 195: 1634-42. PMID 17471433 DOI: 10.1086/517526  0.784
2007 Lun S, Bishai WR. Characterization of a novel cell wall-anchored protein with carboxylesterase activity required for virulence in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 282: 18348-56. PMID 17428787 DOI: 10.1074/jbc.M700035200  0.363
2007 Williams EP, Lee JH, Bishai WR, Colantuoni C, Karakousis PC. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. Journal of Bacteriology. 189: 4234-42. PMID 17384187 DOI: 10.1128/Jb.00201-07  0.436
2007 Lamichhane G, Bishai W. Defining the 'survivasome' of Mycobacterium tuberculosis. Nature Medicine. 13: 280-2. PMID 17342137 DOI: 10.1038/Nm0307-280  0.784
2007 Agarwal N, Woolwine SC, Tyagi S, Bishai WR. Characterization of the Mycobacterium tuberculosis sigma factor SigM by assessment of virulence and identification of SigM-dependent genes. Infection and Immunity. 75: 452-61. PMID 17088352 DOI: 10.1128/Iai.01395-06  0.48
2006 Lamichhane G, Raghunand TR, Morrison NE, Woolwine SC, Tyagi S, Kandavelou K, Bishai WR. Deletion of a Mycobacterium tuberculosis proteasomal ATPase homologue gene produces a slow-growing strain that persists in host tissues. The Journal of Infectious Diseases. 194: 1233-40. PMID 17041849 DOI: 10.1086/508288  0.807
2006 Raghunand TR, Bishai WR. Mapping essential domains of Mycobacterium smegmatis WhmD: insights into WhiB structure and function. Journal of Bacteriology. 188: 6966-76. PMID 16980499 DOI: 10.1128/Jb.00384-06  0.392
2006 Agarwal N, Raghunand TR, Bishai WR. Regulation of the expression of whiB1 in Mycobacterium tuberculosis: role of cAMP receptor protein. Microbiology (Reading, England). 152: 2749-56. PMID 16946269 DOI: 10.1099/Mic.0.28924-0  0.427
2006 Raghunand TR, Bishai WR. Mycobacterium smegmatis whmD and its homologue Mycobacterium tuberculosis whiB2 are functionally equivalent. Microbiology (Reading, England). 152: 2735-47. PMID 16946268 DOI: 10.1099/Mic.0.28911-0  0.476
2006 Hernandez-Abanto SM, Woolwine SC, Jain SK, Bishai WR. Tetracycline-inducible gene expression in mycobacteria within an animal host using modified Streptomyces tcp830 regulatory elements. Archives of Microbiology. 186: 459-64. PMID 16944099 DOI: 10.1007/S00203-006-0160-2  0.31
2006 Geiman DE, Raghunand TR, Agarwal N, Bishai WR. Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes. Antimicrobial Agents and Chemotherapy. 50: 2836-41. PMID 16870781 DOI: 10.1128/Aac.00295-06  0.423
2006 Nuermberger E, Rosenthal I, Tyagi S, Williams KN, Almeida D, Peloquin CA, Bishai WR, Grosset JH. Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 50: 2621-5. PMID 16870750 DOI: 10.1128/Aac.00451-06  0.385
2006 Raghunand TR, Bishai WR, Chen P. Towards establishing a method to screen for inhibitors of essential genes in mycobacteria: evaluation of the acetamidase promoter. International Journal of Antimicrobial Agents. 28: 36-41. PMID 16757153 DOI: 10.1016/J.Ijantimicag.2006.01.012  0.465
2006 Jain SK, Paul-Satyaseela M, Lamichhane G, Kim KS, Bishai WR. Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. The Journal of Infectious Diseases. 193: 1287-95. PMID 16586367 DOI: 10.1086/502631  0.806
2006 Rosenthal IM, Williams K, Tyagi S, Peloquin CA, Vernon AA, Bishai WR, Grosset JH, Nuermberger EL. Potent twice-weekly rifapentine-containing regimens in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 174: 94-101. PMID 16574936 DOI: 10.1164/Rccm.200602-280Oc  0.363
2006 Jain SK, Bishai WR. Adherence to Therapy, Treatment Success, and the Prevention of Resistance Infectious Diseases in Clinical Practice. 14: S15-S18. DOI: 10.1097/01.Idc.0000230543.03875.D4  0.313
2005 Nuermberger E, Helke K, Bishai WR. Low-dose aerosol model of pneumococcal pneumonia in the mouse: utility for evaluation of antimicrobial efficacy. International Journal of Antimicrobial Agents. 26: 497-503. PMID 16289711 DOI: 10.1016/J.Ijantimicag.2005.08.022  0.326
2005 Nuermberger E, Tyagi S, Williams KN, Rosenthal I, Bishai WR, Grosset JH. Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model. American Journal of Respiratory and Critical Care Medicine. 172: 1452-6. PMID 16151038 DOI: 10.1164/Rccm.200507-1047Oc  0.467
2005 Rosenthal IM, Williams K, Tyagi S, Vernon AA, Peloquin CA, Bishai WR, Grosset JH, Nuermberger EL. Weekly moxifloxacin and rifapentine is more active than the denver regimen in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 172: 1457-62. PMID 16141439 DOI: 10.1164/Rccm.200507-1072Oc  0.374
2005 Ginsburg AS, Sun R, Calamita H, Scott CP, Bishai WR, Grosset JH. Emergence of fluoroquinolone resistance in Mycobacterium tuberculosis during continuously dosed moxifloxacin monotherapy in a mouse model Antimicrobial Agents and Chemotherapy. 49: 3977-3979. PMID 16127087 DOI: 10.1128/Aac.49.9.3977-3979.2005  0.451
2005 Tyagi S, Nuermberger E, Yoshimatsu T, Williams K, Rosenthal I, Lounis N, Bishai W, Grosset J. Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis. Antimicrobial Agents and Chemotherapy. 49: 2289-93. PMID 15917523 DOI: 10.1128/Aac.49.6.2289-2293.2005  0.435
2005 Zetola N, Francis JS, Nuermberger EL, Bishai WR. Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat. The Lancet. Infectious Diseases. 5: 275-86. PMID 15854883 DOI: 10.1016/S1473-3099(05)70112-2  0.31
2005 Bishai WR. Clinical significance of pneumococcal resistance and factors influencing outcomes. Treatments in Respiratory Medicine. 19-23. PMID 15846153 DOI: 10.2165/00151829-200504001-00006  0.302
2005 Lamichhane G, Tyagi S, Bishai WR. Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs. Infection and Immunity. 73: 2533-40. PMID 15784600 DOI: 10.1128/Iai.73.4.2533-2540.2005  0.783
2005 Ginsburg AS, Lee J, Woolwine SC, Grosset JH, Hamzeh FM, Bishai WR. Modeling in vivo pharmacokinetics and pharmacodynamics of moxifloxacin therapy for Mycobacterium tuberculosis infection by using a novel cartridge system. Antimicrobial Agents and Chemotherapy. 49: 853-6. PMID 15673788 DOI: 10.1128/Aac.49.2.853-856.2005  0.438
2005 Calamita H, Ko C, Tyagi S, Yoshimatsu T, Morrison NE, Bishai WR. The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence. Cellular Microbiology. 7: 233-44. PMID 15659067 DOI: 10.1111/J.1462-5822.2004.00454.X  0.468
2004 Nuermberger E, Bishai WR, Grosset JH. Latent tuberculosis infection. Seminars in Respiratory and Critical Care Medicine. 25: 317-36. PMID 16088473 DOI: 10.1055/S-2004-829504  0.488
2004 Williams DL, Torrero M, Wheeler PR, Truman RW, Yoder M, Morrison N, Bishai WR, Gillis TP. Biological implications of Mycobacterium leprae gene expression during infection. Journal of Molecular Microbiology and Biotechnology. 8: 58-72. PMID 15741741 DOI: 10.1159/000082081  0.417
2004 Karakousis PC, Yoshimatsu T, Lamichhane G, Woolwine SC, Nuermberger EL, Grosset J, Bishai WR. Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice. The Journal of Experimental Medicine. 200: 647-57. PMID 15353557 DOI: 10.1084/Jem.20040646  0.809
2004 Nuermberger EL, Yoshimatsu T, Tyagi S, Williams K, Rosenthal I, O'Brien RJ, Vernon AA, Chaisson RE, Bishai WR, Grosset JH. Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 170: 1131-4. PMID 15306535 DOI: 10.1164/Rccm.200407-885Oc  0.363
2004 Nuermberger EL, Bishai WR. Antibiotic resistance in Streptococcus pneumoniae: what does the future hold? Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. S363-71. PMID 15127371 DOI: 10.1086/382696  0.333
2004 Sun R, Converse PJ, Ko C, Tyagi S, Morrison NE, Bishai WR. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Molecular Microbiology. 52: 25-38. PMID 15049808 DOI: 10.1111/j.1365-2958.2003.03958.x  0.352
2004 Scott CP, Kumar N, Bishai WR, Manabe YC. Short report: modulation of Mycobacterium tuberculosis infection by Plasmodium in the murine model. The American Journal of Tropical Medicine and Hygiene. 70: 144-8. PMID 14993625  0.397
2004 Nettles RE, Mazo D, Alwood K, Gachuhi R, Maltas G, Wendel K, Cronin W, Hooper N, Bishai W, Sterling TR. Risk factors for relapse and acquired rifamycin resistance after directly observed tuberculosis treatment: a comparison by HIV serostatus and rifamycin use. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 38: 731-6. PMID 14986259 DOI: 10.1086/381675  0.376
2004 Geiman DE, Kaushal D, Ko C, Tyagi S, Manabe YC, Schroeder BG, Fleischmann RD, Morrison NE, Converse PJ, Chen P, Bishai WR. Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infection and Immunity. 72: 1733-45. PMID 14977982 DOI: 10.1128/Iai.72.3.1733-1745.2004  0.344
2004 Dorman SE, Hatem CL, Tyagi S, Aird K, Lopez-Molina J, Pitt ML, Zook BC, Dannenberg AM, Bishai WR, Manabe YC. Susceptibility to tuberculosis: clues from studies with inbred and outbred New Zealand White rabbits. Infection and Immunity. 72: 1700-5. PMID 14977978 DOI: 10.1128/Iai.72.3.1700-1705.2004  0.483
2004 Nuermberger EL, Yoshimatsu T, Tyagi S, Bishai WR, Grosset JH. Paucibacillary tuberculosis in mice after prior aerosol immunization with Mycobacterium bovis BCG. Infection and Immunity. 72: 1065-71. PMID 14742554 DOI: 10.1128/Iai.72.2.1065-1071.2004  0.414
2004 Nuermberger EL, Yoshimatsu T, Tyagi S, O'Brien RJ, Vernon AN, Chaisson RE, Bishai WR, Grosset JH. Moxifloxacin-containing regimen greatly reduces time to culture conversion in murine tuberculosis. American Journal of Respiratory and Critical Care Medicine. 169: 421-6. PMID 14578218 DOI: 10.1164/Rccm.200310-1380Oc  0.489
2004 SCOTT CP, MANABE YC, BISHAI WR, KUMAR N. SHORT REPORT: MODULATION OF MYCOBACTERIUM TUBERCULOSIS INFECTION BY PLASMODIUM IN THE MURINE MODEL The American Journal of Tropical Medicine and Hygiene. 70: 144-148. DOI: 10.4269/Ajtmh.2004.70.144  0.455
2004 Dorman SE, Hatem CL, Tyagi S, Aird K, Lopez-Molina J, Pitt MLM, Zook BC, Dannenberg AM, Bishai WR, Manabe YC. Susceptibility to Tuberculosis: Clues from Studies with Inbred and Outbred New Zealand White Rabbits Infection and Immunity. 72: 3695-3695. DOI: 10.1128/Iai.72.6.3695.2004  0.444
2003 Nuermberger E, Bishai WR. The clinical significance of macrolide-resistant Streptococcus pneumoniae: it's all relative. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 38: 99-103. PMID 14679455 DOI: 10.1086/380126  0.313
2003 Ginsburg AS, Hooper N, Parrish N, Dooley KE, Dorman SE, Booth J, Diener-West M, Merz WG, Bishai WR, Sterling TR. Fluoroquinolone resistance in patients with newly diagnosed tuberculosis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 1448-52. PMID 14614666 DOI: 10.1086/379328  0.491
2003 Ginsburg AS, Woolwine SC, Hooper N, Benjamin WH, Bishai WR, Dorman SE, Sterling TR. The rapid development of fluoroquinolone resistance in M. tuberculosis. The New England Journal of Medicine. 349: 1977-8. PMID 14614180 DOI: 10.1056/Nejm200311133492023  0.494
2003 Manabe YC, Dannenberg AM, Tyagi SK, Hatem CL, Yoder M, Woolwine SC, Zook BC, Pitt ML, Bishai WR. Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis. Infection and Immunity. 71: 6004-11. PMID 14500521 DOI: 10.1128/IAI.71.10.6004-6011.2003  0.428
2003 Ginsburg AS, Grosset JH, Bishai WR. Fluoroquinolones, tuberculosis, and resistance. The Lancet. Infectious Diseases. 3: 432-42. PMID 12837348 DOI: 10.1016/S1473-3099(03)00671-6  0.453
2003 Lamichhane G, Zignol M, Blades NJ, Geiman DE, Dougherty A, Grosset J, Broman KW, Bishai WR. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 7213-8. PMID 12775759 DOI: 10.1073/Pnas.1231432100  0.727
2003 Ando M, Manabe YC, Converse PJ, Miyazaki E, Harrison R, Murphy JR, Bishai WR. Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. Infection and Immunity. 71: 2584-90. PMID 12704132 DOI: 10.1128/Iai.71.5.2584-2590.2003  0.612
2003 Saviola B, Woolwine SC, Bishai WR. Isolation of acid-inducible genes of Mycobacterium tuberculosis with the use of recombinase-based in vivo expression technology. Infection and Immunity. 71: 1379-88. PMID 12595455 DOI: 10.1128/Iai.71.3.1379-1388.2003  0.485
2003 Bishai WR. Issues in the management of bacterial sinusitis. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 127: S3-9. PMID 12511854 DOI: 10.1067/Mhn.2002.130030  0.31
2003 Comstock GW, Bellete B, Ko C, Coberly J, Chaisson RE, Bishai WR. Whole-blood interferon-γ release assay versus the TST: Newer not better [6] Clinical Infectious Diseases. 36: 1209-1210. DOI: 10.1086/374718  0.7
2002 Park WG, Bishai WR, Chaisson RE, Dorman SE. Performance of the microscopic observation drug susceptibility assay in drug susceptibility testing for Mycobacterium tuberculosis. Journal of Clinical Microbiology. 40: 4750-2. PMID 12454186 DOI: 10.1128/Jcm.40.12.4750-4752.2002  0.366
2002 Cronin WA, Golub JE, Lathan MJ, Mukasa LN, Hooper N, Razeq JH, Baruch NG, Mulcahy D, Benjamin WH, Magder LS, Strickland GT, Bishai WR. Molecular epidemiology of tuberculosis in a low- to moderate-incidence state: are contact investigations enough? Emerging Infectious Diseases. 8: 1271-9. PMID 12453355 DOI: 10.3201/Eid0811.020261  0.46
2002 Brennan PJ, Terwilliger T, Barry CE, Manca C, Su H, Reed M, Rutter K, Domenech P, Kaplan G, Li YJ, Wagner D, Bermudez LE, Bodnar K, Flynn J, Campos-Neto A, ... ... Bishai WR, et al. The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135. PMID 12408170 DOI: 10.1054/Tube.2002.0329  0.631
2002 Scott CP, Dos Anjos Filho L, De Queiroz Mello FC, Thornton CG, Bishai WR, Fonseca LS, Kritski AL, Chaisson RE, Manabe YC. Comparison of C18-carboxypropylbetaine and standard N-acetyl-L-cysteine-NaOH processing of respiratory specimens for increasing tuberculosis smear sensitivity in Brazil Journal of Clinical Microbiology. 40: 3219-3222. PMID 12202556 DOI: 10.1128/Jcm.40.9.3219-3222.2002  0.378
2002 Kaushal D, Schroeder BG, Tyagi S, Yoshimatsu T, Scott C, Ko C, Carpenter L, Mehrotra J, Manabe YC, Fleischmann RD, Bishai WR. Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH. Proceedings of the National Academy of Sciences of the United States of America. 99: 8330-5. PMID 12060776 DOI: 10.1073/Pnas.102055799  0.505
2002 Gounder C, De Queiroz Mello FC, Conde MB, Bishai WR, Kritski AL, Chaisson RE, Dorman SE. Field evaluation of a rapid immunochromatographic test for tuberculosis. Journal of Clinical Microbiology. 40: 1989-93. PMID 12037053 DOI: 10.1128/Jcm.40.6.1989-1993.2002  0.41
2002 Yoshimatsu T, Nuermberger E, Tyagi S, Chaisson R, Bishai W, Grosset J. Bactericidal activity of increasing daily and weekly doses of moxifloxacin in murine tuberculosis. Antimicrobial Agents and Chemotherapy. 46: 1875-9. PMID 12019103 DOI: 10.1128/Aac.46.6.1875-1879.2002  0.331
2002 Bellete B, Coberly J, Barnes GL, Ko C, Chaisson RE, Comstock GW, Bishai WR. Evaluation of a whole-blood interferon-gamma release assay for the detection of Mycobacterium tuberculosis infection in 2 study populations. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 34: 1449-56. PMID 12015690 DOI: 10.1086/340397  0.78
2002 Randhawa GS, Bishai WR. Beneficial impact of genome projects on tuberculosis control. Infectious Disease Clinics of North America. 16: 145-61. PMID 11917811 DOI: 10.1016/S0891-5520(03)00050-3  0.488
2002 Manabe YC, Scott CP, Bishai WR. Naturally attenuated, orally administered Mycobacterium microti as a tuberculosis vaccine is better than subcutaneous Mycobacterium bovis BCG Infection and Immunity. 70: 1566-1570. PMID 11854245 DOI: 10.1128/Iai.70.3.1566-1570.2002  0.457
2002 Oursler KK, Moore RD, Bishai WR, Harrington SM, Pope DS, Chaisson RE. Survival of patients with pulmonary tuberculosis: clinical and molecular epidemiologic factors. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 34: 752-9. PMID 11850859 DOI: 10.1086/338784  0.356
2002 Wagner KR, Bishai WR. Issues in the treatment of Mycobacterium tuberculosis in patients with human immunodeficiency virus infection. Aids (London, England). S203-12. PMID 11816169 DOI: 10.1097/00002030-200100005-00024  0.451
2002 Bishai W. Tuberculosis transmission--rogue pathogen or rogue patient? American Journal of Respiratory and Critical Care Medicine. 164: 1104-5. PMID 11673188 DOI: 10.1164/Ajrccm.164.7.2108039C  0.44
2002 Mehrotra J, Bishai WR. Regulation of virulence genes in Mycobacterium tuberculosis. International Journal of Medical Microbiology : Ijmm. 291: 171-82. PMID 11437339 DOI: 10.1078/1438-4221-00113  0.406
2001 Mazurek GH, LoBue PA, Daley CL, Bernardo J, Lardizabal AA, Bishai WR, Iademarco MF, Rothel JS. Comparison of a whole-blood interferon gamma assay with tuberculin skin testing for detecting latent Mycobacterium tuberculosis infection. Jama. 286: 1740-7. PMID 11594899 DOI: 10.1001/Jama.286.14.1740  0.432
2001 Golub JE, Cronin WA, Obasanjo OO, Coggin W, Moore K, Pope DS, Thompson D, Sterling TR, Harrington S, Bishai WR, Chaisson RE. Transmission of Mycobacterium tuberculosis through casual contact with an infectious case. Archives of Internal Medicine. 161: 2254-8. PMID 11575983 DOI: 10.1001/Archinte.161.18.2254  0.461
2001 Cronin WA, Golub JE, Magder LS, Baruch NG, Lathan MJ, Mukasa LN, Hooper N, Razeq JH, Mulcahy D, Benjamin WH, Bishai WR. Epidemiologic usefulness of spoligotyping for secondary typing of Mycobacterium tuberculosis isolates with low copy numbers of IS6110 Journal of Clinical Microbiology. 39: 3709-3711. PMID 11574598 DOI: 10.1128/Jcm.39.10.3709-3711.2001  0.472
2001 Wendel KA, Alwood KS, Gachuhi R, Chaisson RE, Bishai WR, Sterling TR. Paradoxical worsening of tuberculosis in HIV-infected persons. Chest. 120: 193-7. PMID 11451837 DOI: 10.1378/Chest.120.1.193  0.397
2001 Parrish NM, Kuhajda FP, Heine HS, Bishai WR, Dick JD. Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis. The Journal of Antimicrobial Chemotherapy. 43: 219-26. PMID 11252327 DOI: 10.1093/Jac/43.2.219  0.369
2001 Bishai WR. Rekindling old controversy on elusive lair of latent tuberculosis. Lancet (London, England). 356: 2113-4. PMID 11191532 DOI: 10.1016/S0140-6736(00)03485-1  0.483
2001 Manabe YC, Bishai WR. Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting. Nature Medicine. 6: 1327-9. PMID 11100115 DOI: 10.1038/82139  0.493
2000 Dannenberg AM, Bishai WR, Parrish N, Ruiz R, Johnson W, Zook BC, Boles JW, Pitt LM. Efficacies of BCG and vole bacillus (Mycobacterium microti) vaccines in preventing clinically apparent pulmonary tuberculosis in rabbits: a preliminary report. Vaccine. 19: 796-800. PMID 11115701 DOI: 10.1016/S0264-410X(00)00300-5  0.416
2000 Chen P, Ruiz RE, Li Q, Silver RF, Bishai WR. Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF Infection and Immunity. 68: 5575-5580. PMID 10992456 DOI: 10.1128/Iai.68.10.5575-5580.2000  0.4
2000 Bishai W. Lipid lunch for persistent pathogen. Nature. 406: 683-5. PMID 10963578 DOI: 10.1038/35021159  0.46
2000 Gomez JE, Bishai WR. whmD is an essential mycobacterial gene required for proper septation and cell division Proceedings of the National Academy of Sciences of the United States of America. 97: 8554-8559. PMID 10880571 DOI: 10.1073/Pnas.140225297  0.645
2000 Ellingson JLE, Stabel JR, Bishai WR, Frothingham R, Miller JM. Evaluation of the accuracy and reproducibility of a practical PCR panel assay for rapid detection and differentiation of Mycobacterium avium subspecies Molecular and Cellular Probes. 14: 153-161. PMID 10860713 DOI: 10.1006/Mcpr.2000.0299  0.315
2000 Soliveri JA, Gomez J, Bishai WR, Chater KF. Multiple paralogous genes related to the Streptomyces coelicolor developmental regulatory gene whiB are present in Streptomyces and other actinomycetes. Microbiology (Reading, England). 333-343. PMID 10708372 DOI: 10.1099/00221287-146-2-333  0.337
2000 Sterling TR, Pope DS, Bishai WR, Harrington S, Gershon RR, Chaisson RE. Transmission of Mycobacterium tuberculosis from a cadaver to an embalmer. The New England Journal of Medicine. 342: 246-8. PMID 10648766 DOI: 10.1056/Nejm200001273420404  0.457
1999 Manabe YC, Saviola BJ, Sun L, Murphy JR, Bishai WR. Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12844-8. PMID 10536010 DOI: 10.1073/Pnas.96.22.12844  0.719
1999 Sterling TR, Alwood K, Gachuhi R, Coggin W, Blazes D, Bishai WR, Chaisson RE. Relapse rates after short-course (6-month) treatment of tuberculosis in HIV-infected and uninfected persons. Aids (London, England). 13: 1899-904. PMID 10513648 DOI: 10.1097/00002030-199910010-00012  0.388
1999 Miyazaki E, Chaisson RE, Bishai WR. Analysis of rifapentine for preventive therapy in the Cornell mouse model of latent tuberculosis Antimicrobial Agents and Chemotherapy. 43: 2126-2130. PMID 10471552 DOI: 10.1128/Aac.43.9.2126  0.394
1999 Head SR, Parikh K, Rogers YH, Bishai W, Goelet P, Boyce-Jacino MT. Solid-phase sequence scanning for drug resistance detection in tuberculosis Molecular and Cellular Probes. 13: 81-87. PMID 10208797 DOI: 10.1006/Mcpr.1998.0212  0.397
1999 Kimura M, Converse PJ, Astemborski J, Rothel JS, Vlahov D, Comstock GW, Graham NM, Chaisson RE, Bishai WR. Comparison between a whole blood interferon-gamma release assay and tuberculin skin testing for the detection of tuberculosis infection among patients at risk for tuberculosis exposure. The Journal of Infectious Diseases. 179: 1297-300. PMID 10191241 DOI: 10.1086/314707  0.384
1999 Bishai W. The Mycobacterium tuberculosis genomic sequence: anatomy of a master adaptor. Trends in Microbiology. 6: 464-5. PMID 10036721 DOI: 10.1016/S0966-842X(98)01414-0  0.389
1999 Miyazaki E, Miyazaki M, Chen JM, Chaisson RE, Bishai WR. Moxifloxacin (BAY12-8039), a new 8-methoxyquinolone, is active in a mouse model of tuberculosis Antimicrobial Agents and Chemotherapy. 43: 85-89. PMID 9869570 DOI: 10.1128/Aac.43.1.85  0.403
1999 Miyazaki E, Chen J, Ko C, Bishai WR. The Staphylococcus aureus rsbW(orf159) Gene Encodes an Anti-Sigma Factor of SigB Journal of Bacteriology. 181: 2846-2851. DOI: 10.1128/Jb.181.9.2846-2851.1999  0.306
1999 Manabe YC, Chen JM, Ko CG, Chen P, Bishai WR. Conditional Sigma Factor Expression, Using the Inducible Acetamidase Promoter, Reveals that the Mycobacterium tuberculosis sigF Gene Modulates Expression of the 16-Kilodalton Alpha-Crystallin Homologue Journal of Bacteriology. 181: 7629-7633. DOI: 10.1128/Jb.181.24.7629-7633.1999  0.342
1999 Bishai WR, Dannenberg AM, Parrish N, Ruiz R, Chen P, Zook BC, Johnson W, Boles JW, Pitt MLM. Virulence of Mycobacterium tuberculosisCDC1551 and H37Rv in Rabbits Evaluated by Lurie’s Pulmonary Tubercle Count Method Infection and Immunity. 67: 4931-4934. DOI: 10.1128/Iai.67.9.4931-4934.1999  0.406
1999 Michele TM, Ko C, Bishai WR. Exposure to Antibiotics Induces Expression of theMycobacterium tuberculosis sigF Gene: Implications for Chemotherapy against Mycobacterial Persistors Antimicrobial Agents and Chemotherapy. 43: 218-225. DOI: 10.1128/Aac.43.2.218  0.366
1999 Bishai W. Out of Africa: daunting data and dazzling discussion on TB Trends in Microbiology. 7: 424. DOI: 10.1016/S0966-842X(99)01596-6  0.462
1998 Bishai WR, Graham NM, Harrington S, Pope DS, Hooper N, Astemborski J, Sheely L, Vlahov D, Glass GE, Chaisson RE. Molecular and geographic patterns of tuberculosis transmission after 15 years of directly observed therapy. Jama. 280: 1679-84. PMID 9831999 DOI: 10.1001/Jama.280.19.1679  0.401
1998 DeMaio J, Zhang Y, Ko C, Bishai WR. Mycobacterium tuberculosis sigF is part of a gene cluster with similarities to the Bacillus subtilis sigF and sigB operons. Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease. 78: 3-12. PMID 9666957 DOI: 10.1016/S0962-8479(97)90010-1  0.404
1998 Parrish NM, Dick JD, Bishai WR. Mechanisms of latency in Mycobacterium tuberculosis. Trends in Microbiology. 6: 107-12. PMID 9582936 DOI: 10.1016/S0966-842X(98)01216-5  0.511
1998 Chen P, Bishai WR. Novel Selection for Isoniazid (INH) Resistance Genes Supports a Role for NAD+-Binding Proteins in Mycobacterial INH Resistance Infection and Immunity. 66: 5099-5106. DOI: 10.1128/Iai.66.11.5099-5106.1998  0.47
1997 Gomez JE, Chen JM, Bishai WR. Sigma factors of mycobacterium tuberculosis Tubercle and Lung Disease. 78: 175-183. PMID 9713650 DOI: 10.1016/S0962-8479(97)90024-1  0.71
1997 Bishai WR, Chaisson RE. Short-course chemoprophylaxis for tuberculosis Clinics in Chest Medicine. 18: 115-122. PMID 9098615 DOI: 10.1016/S0272-5231(05)70360-9  0.452
1996 Jacobs W, Brennan P, Curlin G, Ginsberg A, Adams M, Fleischmann R, Fraser C, Venter JC, Shinnick T, Bishai W, Smith H, Stover K, Hatfull G. Comparative sequencing. Science (New York, N.Y.). 274: 17-8. PMID 8848713 DOI: 10.1126/science.274.5284.17a  0.411
1996 Bishai WR, Graham NM, Harrington S, Page C, Moore-Rice K, Hooper N, Chaisson RE. Brief report: rifampin-resistant tuberculosis in a patient receiving rifabutin prophylaxis. The New England Journal of Medicine. 334: 1573-6. PMID 8628338 DOI: 10.1056/Nejm199606133342404  0.451
1996 DeMaio J, Zhang Y, Ko C, Young DB, Bishai WR. A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 93: 2790-4. PMID 8610119 DOI: 10.1073/Pnas.93.7.2790  0.468
1995 Howard NS, Gomez JE, Ko C, Bishai WR. Color selection with a hygromycin-resistance-based Escherichia coli-mycobacterial shuttle vector Gene. 166: 181-182. PMID 8529888 DOI: 10.1016/0378-1119(95)00597-X  0.616
1994 Bishai WR, Smith HO, Barcak GJ. A peroxide/ascorbate-inducible catalase from Haemophilus influenzae is homologous to the Escherichia coli katE gene product. Journal of Bacteriology. 176: 2914-21. PMID 8188593 DOI: 10.1128/Jb.176.10.2914-2921.1994  0.514
1994 Bishai WR, Howard NS, Winkelstein JA, Smith HO. Characterization and virulence analysis of catalase mutants of Haemophilus influenzae. Infection and Immunity. 62: 4855-60. PMID 7927766 DOI: 10.1128/Iai.62.11.4855-4860.1994  0.538
1989 Williams DP, Parker K, Bacha P, Bishai W, Borowski M, Genbauffe F, Strom TB, Murphy JR. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein. Protein Engineering. 1: 493-8. PMID 3334101 DOI: 10.1093/protein/1.6.493  0.551
1987 Bishai WR, Miyanohara A, Murphy JR. Cloning and expression in Escherichia coli of three fragments of diphtheria toxin truncated within fragment B. Journal of Bacteriology. 169: 1554-63. PMID 3549695  0.59
1987 Bishai WR, Rappuoli R, Murphy JR. High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli. Journal of Bacteriology. 169: 5140-51. PMID 3312166  0.573
1986 Murphy JR, Bishai W, Borowski M, Miyanohara A, Boyd J, Nagle S. Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 83: 8258-62. PMID 3095831 DOI: 10.1073/pnas.83.21.8258  0.551
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