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Brian P. Smart, Ph.D. - Publications

Affiliations: 
2006 University of Washington, Seattle, Seattle, WA 
Area:
medicinal enzymology
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Bryant KJ, Bidgood MJ, Lei PW, Taberner M, Salom C, Kumar V, Lee L, Church WB, Courtenay B, Smart BP, Gelb MH, Cahill MA, Graham GG, McNeil HP, Scott KF. A bifunctional role for group IIA secreted phospholipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolism. The Journal of Biological Chemistry. 286: 2492-503. PMID 21068383 DOI: 10.1074/Jbc.M110.123927  0.505
2007 Bendale P, Olepu S, Suryadevara PK, Bulbule V, Rivas K, Nallan L, Smart B, Yokoyama K, Ankala S, Pendyala PR, Floyd D, Lombardo LJ, Williams DK, Buckner FS, Chakrabarti D, et al. Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials. Journal of Medicinal Chemistry. 50: 4585-605. PMID 17722901 DOI: 10.1021/Jm0703340  0.583
2007 Van Voorhis WC, Rivas KL, Bendale P, Nallan L, Hornéy C, Barrett LK, Bauer KD, Smart BP, Ankala S, Hucke O, Verlinde CL, Chakrabarti D, Strickland C, Yokoyama K, Buckner FS, et al. Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. Antimicrobial Agents and Chemotherapy. 51: 3659-71. PMID 17606674 DOI: 10.1128/Aac.00246-07  0.493
2006 Smart BP, Oslund RC, Walsh LA, Gelb MH. The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding. Journal of Medicinal Chemistry. 49: 2858-60. PMID 16686528 DOI: 10.1021/Jm060136T  0.592
2006 Ni Z, Okeley NM, Smart BP, Gelb MH. Intracellular actions of group IIA secreted phospholipase A2 and group IVA cytosolic phospholipase A2 contribute to arachidonic acid release and prostaglandin production in rat gastric mucosal cells and transfected human embryonic kidney cells. The Journal of Biological Chemistry. 281: 16245-55. PMID 16603549 DOI: 10.1074/Jbc.M513874200  0.487
2005 Rubin BB, Downey GP, Koh A, Degousee N, Ghomashchi F, Nallan L, Stefanski E, Harkin DW, Sun C, Smart BP, Lindsay TF, Cherepanov V, Vachon E, Kelvin D, Sadilek M, et al. Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity. The Journal of Biological Chemistry. 280: 7519-29. PMID 15475363 DOI: 10.1074/Jbc.M407438200  0.465
2004 Smart BP, Pan YH, Weeks AK, Bollinger JG, Bahnson BJ, Gelb MH. Inhibition of the complete set of mammalian secreted phospholipases A(2) by indole analogues: a structure-guided study. Bioorganic & Medicinal Chemistry. 12: 1737-49. PMID 15028265 DOI: 10.1016/J.Bmc.2004.01.022  0.628
2002 Degousee N, Ghomashchi F, Stefanski E, Singer A, Smart BP, Borregaard N, Reithmeier R, Lindsay TF, Lichtenberger C, Reinisch W, Lambeau G, Arm J, Tischfield J, Gelb MH, Rubin BB. Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis. The Journal of Biological Chemistry. 277: 5061-73. PMID 11741884 DOI: 10.1074/Jbc.M109083200  0.551
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