Roy A. Mariuzza - Publications

Affiliations: 
Molecular and Cell Biology University of Maryland, College Park, College Park, MD 
Area:
Molecular Biology, Biochemistry, General Biophysics

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wu D, Yin R, Chen G, Ribeiro-Filho HV, Cheung M, Robbins PF, Mariuzza RA, Pierce BG. Structural characterization and AlphaFold modeling of human T cell receptor recognition of NRAS cancer neoantigens. Biorxiv : the Preprint Server For Biology. PMID 38826362 DOI: 10.1101/2024.05.21.595215  0.34
2024 Adam K, Lipatova Z, Abdul Ghafoor Raja M, Mishra AK, Mariuzza RA, Workman CJ, Vignali DAA. Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 38775415 DOI: 10.4049/jimmunol.2300673  0.32
2024 Mariuzza RA, Shahid S, Karade SS. The immune checkpoint receptor LAG3: Structure, function, and target for cancer immunotherapy. The Journal of Biological Chemistry. 300: 107241. PMID 38556085 DOI: 10.1016/j.jbc.2024.107241  0.388
2023 Mariuzza RA, Wu D, Pierce BG. Structural basis for T cell recognition of cancer neoantigens and implications for predicting neoepitope immunogenicity. Frontiers in Immunology. 14: 1303304. PMID 38045695 DOI: 10.3389/fimmu.2023.1303304  0.353
2023 Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, ... ... Mariuzza R, et al. SARS-CoV-2 infection establishes a stable and age-independent CD8 T cell response against a dominant nucleocapsid epitope using restricted T cell receptors. Nature Communications. 14: 6725. PMID 37872153 DOI: 10.1038/s41467-023-42430-z  0.309
2023 Mishra AK, Shahid S, Karade SS, Agnihotri P, Kolesnikov A, Hasan SS, Mariuzza RA. CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure (London, England : 1993). PMID 37619561 DOI: 10.1016/j.str.2023.07.013  0.343
2023 Wu D, Efimov GA, Bogolyubova AV, Pierce BG, Mariuzza RA. Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity. The Journal of Biological Chemistry. 103035. PMID 36806685 DOI: 10.1016/j.jbc.2023.103035  0.35
2022 Rushdi MN, Pan V, Li K, Choi HK, Travaglino S, Hong J, Griffitts F, Agnihotri P, Mariuzza RA, Ke Y, Zhu C. Cooperative binding of T cell receptor and CD4 to peptide-MHC enhances antigen sensitivity. Nature Communications. 13: 7055. PMID 36396644 DOI: 10.1038/s41467-022-34587-w  0.317
2022 Agnihotri P, Mishra AK, Agarwal P, Vignali KM, Workman CJ, Vignali DAA, Mariuzza RA. Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3. Journal of Immunology (Baltimore, Md. : 1950). PMID 36104110 DOI: 10.4049/jimmunol.2200309  0.371
2022 Wu D, Gowathaman R, Pierce BG, Mariuzza RA. T cell receptors employ diverse strategies to target a p53 cancer neoantigen. The Journal of Biological Chemistry. 298: 101684. PMID 35124005 DOI: 10.1016/j.jbc.2022.101684  0.314
2022 Wu D, Kolesnikov A, Yin R, Guest JD, Gowthaman R, Shmelev A, Serdyuk Y, Dianov DV, Efimov GA, Pierce BG, Mariuzza RA. Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nature Communications. 13: 19. PMID 35013235 DOI: 10.1038/s41467-021-27669-8  0.36
2020 He Y, Agnihotri P, Rangarajan S, Chen Y, Kerzic MC, Ma B, Nussinov R, Mariuzza RA, Orban J. Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs). Journal of Molecular Biology. PMID 33157083 DOI: 10.1016/j.jmb.2020.10.031  0.387
2020 Andrianov AK, Marin A, Wang R, Chowdhury A, Agnihotri P, Yunus AS, Pierce BG, Mariuzza RA, Fuerst TR. In Vivo and In Vitro Potency of Polyphosphazene Immunoadjuvants with Hepatitis C Virus Antigen and the Role of Their Supramolecular Assembly. Molecular Pharmaceutics. PMID 32530637 DOI: 10.1021/Acs.Molpharmaceut.0C00487  0.343
2020 Wu D, Gallagher DT, Gowthaman R, Pierce BG, Mariuzza RA. Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nature Communications. 11: 2908. PMID 32518267 DOI: 10.1038/S41467-020-16755-Y  0.4
2019 Mariuzza RA, Agnihotri P, Orban J. The structural basis of T cell receptor (TCR) activation: An enduring enigma. The Journal of Biological Chemistry. PMID 31848223 DOI: 10.1074/Jbc.Rev119.009411  0.449
2019 Karade SS, Mariuzza RA. How Natural Killer Cell Receptors Stick to Cell-Cell Adhesion Proteins. Structure (London, England : 1993). 27: 209-210. PMID 30726753 DOI: 10.1016/J.Str.2019.01.007  0.394
2019 Urbanowicz RA, Wang R, Schiel JE, Keck ZY, Kerzic MC, Lau P, Rangarajan S, Garagusi KJ, Tan L, Guest JD, Ball JK, Pierce BG, Mariuzza RA, Foung SKH, Fuerst TR. Antigenicity and Immunogenicity of Differentially Glycosylated HCV E2 Envelope Proteins Expressed in Mammalian and Insect Cells. Journal of Virology. PMID 30651366 DOI: 10.1128/Jvi.01403-18  0.348
2019 Ma B, Orban JP, Mariuzza R, Nussinov R. Allosteric Effects and Signal Transduction in the Peptide-MHC Binding to a Human T Cell Receptor Biophysical Journal. 116: 341a. DOI: 10.1016/J.Bpj.2018.11.1857  0.431
2018 Rangarajan S, He Y, Chen Y, Kerzic MC, Ma B, Gowthaman R, Pierce BG, Nussinov R, Mariuzza RA, Orban J. Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites. The Journal of Biological Chemistry. PMID 30135211 DOI: 10.1074/Jbc.Ra118.003832  0.381
2018 Li SS, Ogbomo H, Mansour MK, Xiang RF, Szabo L, Munro F, Mukherjee P, Mariuzza RA, Amrein M, Vyas JM, Robbins SM, Mody CH. Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida. Nature Communications. 9: 751. PMID 29467448 DOI: 10.1038/S41467-018-03014-4  0.35
2018 Mishra AK, Mariuzza RA. Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing. Frontiers in Immunology. 9: 117. PMID 29449843 DOI: 10.3389/Fimmu.2018.00117  0.433
2018 He Y, Rangarajan S, Chen Y, Kerzic M, Ma B, Gowthaman R, Pierce B, Nussinov R, Mariuzza R, Orban J. Long-range effects induced by peptide-MHC binding to a human T cell receptor: Implications for the initiation of T cell signaling Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr27441  0.433
2017 Yang X, Chen G, Weng NP, Mariuzza RA. Structural basis for clonal diversity of the human T cell response to a dominant influenza virus epitope. The Journal of Biological Chemistry. PMID 28931605 DOI: 10.1074/Jbc.M117.810382  0.417
2017 Chen G, Yang X, Ko A, Sun X, Gao M, Zhang Y, Shi A, Mariuzza RA, Weng NP. Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8(+) TCR Repertoires to Immunodominant Viral Antigens. Cell Reports. 19: 569-583. PMID 28423320 DOI: 10.1016/J.Celrep.2017.03.072  0.437
2016 Romasanta PN, Curto LM, Sarratea MB, Noly Truant S, Antonoglou MB, Fernández Lynch MJ, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL. Kinetic and Thermodynamic Studies of the Interaction between Activating and Inhibitory NK Receptors and MHC-I Molecules. The Biochemical Journal. PMID 27831490 DOI: 10.1042/Bcj20160876  0.471
2016 Pierce BG, Keck ZY, Lau P, Fauvelle C, Gowthaman R, Baumert TF, Fuerst TR, Mariuzza RA, Foung SK. Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791171 DOI: 10.1073/Pnas.1614942113  0.343
2016 Xu X, Narni-Mancinelli E, Cantoni C, Li Y, Guia S, Gauthier L, Chen Q, Moretta A, Vély F, Eisenstein E, Rangarajan S, Vivier E, Mariuzza RA. Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30. Journal of Molecular Biology. PMID 27663271 DOI: 10.1016/j.jmb.2016.09.011  0.323
2016 Keck ZY, Wang Y, Lau P, Lund G, Rangarajan S, Fauvelle C, Liao GC, Holtsberg FW, Warfield KL, Aman MJ, Pierce BG, Fuerst TR, Bailey JR, Baumert TF, Mariuzza RA, et al. Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute HCV infection. Hepatology (Baltimore, Md.). PMID 27641232 DOI: 10.1002/Hep.28850  0.313
2015 Wang WJ, Cheng W, Luo M, Yan Q, Yu HM, Li Q, Cao DD, Huang S, Xu A, Mariuzza RA, Chen Y, Zhou CZ. Activity Augmentation of Amphioxus Peptidoglycan Recognition Protein BbtPGRP3 via Fusion with a Chitin Binding Domain. Plos One. 10: e0140953. PMID 26479246 DOI: 10.1371/Journal.Pone.0140953  0.358
2015 Yang X, Gao M, Chen G, Pierce BG, Lu J, Weng NP, Mariuzza RA. Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope. The Journal of Biological Chemistry. PMID 26429912 DOI: 10.1074/Jbc.M115.691311  0.466
2015 Yang X, Mariuzza RA. Pre-T-cell receptor binds MHC: Implications for thymocyte signaling and selection. Proceedings of the National Academy of Sciences of the United States of America. PMID 26134398 DOI: 10.1073/Pnas.1510127112  0.411
2015 He Y, Rangarajan S, Kerzic M, Luo M, Chen Y, Wang Q, Yin Y, Workman CJ, Vignali KM, Vignali DA, Mariuzza RA, Orban J. Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR. The Journal of Biological Chemistry. PMID 26109064 DOI: 10.1074/Jbc.M115.663799  0.597
2015 Xu X, Li Y, Gauthier L, Chen Q, Vivier E, Mariuzza RA. Expression, crystallization and X-ray diffraction analysis of a complex between B7-H6, a tumor cell ligand for the natural cytotoxicity receptor NKp30, and an inhibitory antibody. Acta Crystallographica. Section F, Structural Biology Communications. 71: 697-701. PMID 26057798 DOI: 10.1107/S2053230X15006755  0.359
2015 De Marzi MC, Todone M, Ganem MB, Wang Q, Mariuzza RA, Fernández MM, Malchiodi EL. Peptidoglycan recognition protein-peptidoglycan complexes increase monocyte/macrophage activation and enhance the inflammatory response. Immunology. 145: 429-42. PMID 25752767 DOI: 10.1111/Imm.12460  0.36
2015 Li Y, Pierce BG, Wang Q, Keck ZY, Fuerst TR, Foung SK, Mariuzza RA. Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody. The Journal of Biological Chemistry. 290: 10117-25. PMID 25737449 DOI: 10.1074/Jbc.M115.643528  0.331
2014 Holland SJ, Gao M, Hirano M, Iyer LM, Luo M, Schorpp M, Cooper MD, Aravind L, Mariuzza RA, Boehm T. Selection of the lamprey VLRC antigen receptor repertoire. Proceedings of the National Academy of Sciences of the United States of America. 111: 14834-9. PMID 25228760 DOI: 10.1073/Pnas.1415655111  0.39
2014 Li Y, Mariuzza RA. Structural basis for recognition of cellular and viral ligands by NK cell receptors. Frontiers in Immunology. 5: 123. PMID 24723923 DOI: 10.3389/Fimmu.2014.00123  0.44
2014 Rangarajan S, Mariuzza RA. T cell receptor bias for MHC: co-evolution or co-receptors? Cellular and Molecular Life Sciences : Cmls. 71: 3059-68. PMID 24633202 DOI: 10.1007/s00018-014-1600-9  0.413
2014 Romasanta PN, Curto LM, Urtasun N, Sarratea MB, Chiappini S, Miranda MV, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL. A positive cooperativity binding model between Ly49 natural killer cell receptors and the viral immunoevasin m157: kinetic and thermodynamic studies. The Journal of Biological Chemistry. 289: 5083-96. PMID 24379405 DOI: 10.1074/Jbc.M113.532929  0.346
2014 Scott DR, Velikovsky CA, Mariuzza RA, Marino JP, Krueger S, Nanda H. Biophysical Properties of Immune Receptor Proteins at the Membrane Interface Biophysical Journal. 106: 520a. DOI: 10.1016/J.Bpj.2013.11.2903  0.373
2013 Chen S, Li Y, Depontieu FR, McMiller TL, English AM, Shabanowitz J, Kos F, Sidney J, Sette A, Rosenberg SA, Hunt DF, Mariuzza RA, Topalian SL. Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 191: 5097-106. PMID 24108701 DOI: 10.4049/Jimmunol.1300467  0.435
2013 Li Y, Yin Y, Mariuzza RA. Structural and biophysical insights into the role of CD4 and CD8 in T cell activation. Frontiers in Immunology. 4: 206. PMID 23885256 DOI: 10.3389/Fimmu.2013.00206  0.629
2013 Li Y, Wang Q, Chen S, Brown PH, Mariuzza RA. Structure of NKp65 bound to its keratinocyte ligand reveals basis for genetically linked recognition in natural killer gene complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 11505-10. PMID 23803857 DOI: 10.1073/Pnas.1303300110  0.455
2013 Ganem MB, De Marzi MC, Fernández-Lynch MJ, Jancic C, Vermeulen M, Geffner J, Mariuzza RA, Fernández MM, Malchiodi EL. Uptake and intracellular trafficking of superantigens in dendritic cells. Plos One. 8: e66244. PMID 23799083 DOI: 10.1371/Journal.Pone.0066244  0.375
2013 Luo M, Velikovsky CA, Yang X, Siddiqui MA, Hong X, Barchi JJ, Gildersleeve JC, Pancer Z, Mariuzza RA. Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor Journal of Biological Chemistry. 288: 23597-23606. PMID 23782692 DOI: 10.1074/jbc.M113.480467  0.362
2013 Deng L, Luo M, Velikovsky A, Mariuzza RA. Structural insights into the evolution of the adaptive immune system. Annual Review of Biophysics. 42: 191-215. PMID 23451889 DOI: 10.1146/Annurev-Biophys-083012-130422  0.452
2013 Hong X, Ma MZ, Gildersleeve JC, Chowdhury S, Barchi JJ, Mariuzza RA, Murphy MB, Mao L, Pancer Z. Sugar-binding proteins from fish: Selection of high affinity "lambodies" that recognize biomedically relevant glycans Acs Chemical Biology. 8: 152-160. PMID 23030719 DOI: 10.1021/Cb300399S  0.387
2012 Yin Y, Li Y, Mariuzza RA. Structural basis for self-recognition by autoimmune T-cell receptors. Immunological Reviews. 250: 32-48. PMID 23046121 DOI: 10.1111/Imr.12002  0.635
2012 Deng L, Langley RJ, Wang Q, Topalian SL, Mariuzza RA. Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3. Proceedings of the National Academy of Sciences of the United States of America. 109: 14960-5. PMID 22930819 DOI: 10.1073/Pnas.1207186109  0.491
2012 Yin Y, Wang XX, Mariuzza RA. Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proceedings of the National Academy of Sciences of the United States of America. 109: 5405-10. PMID 22431638 DOI: 10.1073/Pnas.1118801109  0.627
2011 Back J, Angelov GS, Mariuzza RA, Held W. The interaction with H-2D(d) in cis is associated with a conformational change in the Ly49A NK cell receptor. Frontiers in Immunology. 2: 55. PMID 22566845 DOI: 10.3389/Fimmu.2011.00055  0.436
2011 Wang XX, Li Y, Yin Y, Mo M, Wang Q, Gao W, Wang L, Mariuzza RA. Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 15960-5. PMID 21900604 DOI: 10.1073/Pnas.1109438108  0.618
2011 Held W, Mariuzza RA. Cis-trans interactions of cell surface receptors: biological roles and structural basis. Cellular and Molecular Life Sciences : Cmls. 68: 3469-78. PMID 21863376 DOI: 10.1007/S00018-011-0798-Z  0.382
2011 Li Y, Wang Q, Mariuzza RA. Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6. The Journal of Experimental Medicine. 208: 703-14. PMID 21422170 DOI: 10.1084/Jem.20102548  0.364
2011 Yin Y, Li Y, Kerzic MC, Martin R, Mariuzza RA. Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection. The Embo Journal. 30: 1137-48. PMID 21297580 DOI: 10.1038/Emboj.2011.21  0.642
2011 Fernández MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL. Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain. The Journal of Biological Chemistry. 286: 1189-95. PMID 21059660 DOI: 10.1074/Jbc.M110.142471  0.484
2010 Cho S, Swaminathan CP, Bonsor DA, Kerzic MC, Guan R, Yang J, Kieke MC, Andersen PS, Kranz DM, Mariuzza RA, Sundberg EJ. Assessing energetic contributions to binding from a disordered region in a protein-protein interaction . Biochemistry. 49: 9256-68. PMID 20836565 DOI: 10.1021/Bi1008968  0.347
2010 Deng L, Velikovsky CA, Xu G, Iyer LM, Tasumi S, Kerzic MC, Flajnik MF, Aravind L, Pancer Z, Mariuzza RA. A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey. Proceedings of the National Academy of Sciences of the United States of America. 107: 13408-13. PMID 20616002 DOI: 10.1073/Pnas.1005475107  0.497
2010 Mariuzza RA, Velikovsky CA, Deng L, Xu G, Pancer Z. Structural insights into the evolution of the adaptive immune system: the variable lymphocyte receptors of jawless vertebrates. Biological Chemistry. 391: 753-60. PMID 20482318 DOI: 10.1515/Bc.2010.091  0.467
2010 Li Y, Depontieu FR, Sidney J, Salay TM, Engelhard VH, Hunt DF, Sette A, Topalian SL, Mariuzza RA. Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells. Journal of Molecular Biology. 399: 596-603. PMID 20417641 DOI: 10.1016/J.Jmb.2010.04.037  0.498
2009 Yin Y, Mariuzza RA. The multiple mechanisms of T cell receptor cross-reactivity. Immunity. 31: 849-51. PMID 20064442 DOI: 10.1016/J.Immuni.2009.12.002  0.6
2009 Back J, Malchiodi EL, Cho S, Scarpellino L, Schneider P, Kerzic MC, Mariuzza RA, Held W. Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity. 31: 598-608. PMID 19818651 DOI: 10.1016/J.Immuni.2009.07.007  0.438
2009 Wucherpfennig KW, Call MJ, Deng L, Mariuzza R. Structural alterations in peptide-MHC recognition by self-reactive T cell receptors. Current Opinion in Immunology. 21: 590-5. PMID 19699075 DOI: 10.1016/J.Coi.2009.07.008  0.476
2009 Tasumi S, Velikovsky CA, Xu G, Gai SA, Wittrup KD, Flajnik MF, Mariuzza RA, Pancer Z. High-affinity lamprey VLRA and VLRB monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 106: 12891-6. PMID 19625627 DOI: 10.1073/Pnas.0904443106  0.436
2009 Li Y, Hofmann M, Wang Q, Teng L, Chlewicki LK, Pircher H, Mariuzza RA. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity. 31: 35-46. PMID 19604491 DOI: 10.1016/J.Immuni.2009.04.019  0.412
2009 Velikovsky CA, Deng L, Tasumi S, Iyer LM, Kerzic MC, Aravind L, Pancer Z, Mariuzza RA. Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen. Nature Structural & Molecular Biology. 16: 725-30. PMID 19543291 DOI: 10.1038/Nsmb.1619  0.468
2009 Li Y, Cao C, Jia W, Yu L, Mo M, Wang Q, Huang Y, Lim JM, Ishihara M, Wells L, Azadi P, Robinson H, He YW, Zhang L, Mariuzza RA. Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. The Embo Journal. 28: 286-97. PMID 19153605 DOI: 10.1038/Emboj.2008.288  0.383
2008 Chlewicki LK, Velikovsky CA, Balakrishnan V, Mariuzza RA, Kumar V. Molecular basis of the dual functions of 2B4 (CD244). Journal of Immunology (Baltimore, Md. : 1950). 180: 8159-67. PMID 18523281 DOI: 10.4049/Jimmunol.180.12.8159  0.344
2008 Deng L, Cho S, Malchiodi EL, Kerzic MC, Dam J, Mariuzza RA. Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors. The Journal of Biological Chemistry. 283: 16840-9. PMID 18426793 DOI: 10.1074/Jbc.M801526200  0.458
2008 Pancer Z, Mariuzza RA. The oldest antibodies newly discovered. Nature Biotechnology. 26: 402-3. PMID 18392023 DOI: 10.1038/Nbt0408-402  0.323
2008 Held W, Mariuzza RA. Cis interactions of immunoreceptors with MHC and non-MHC ligands. Nature Reviews. Immunology. 8: 269-78. PMID 18309314 DOI: 10.1038/Nri2278  0.386
2008 Moran O, Roessle MW, Mariuzza RA, Dimasi N. Structural features of the full-length adaptor protein GADS in solution determined using small-angle X-ray scattering. Biophysical Journal. 94: 1766-72. PMID 17993503 DOI: 10.1529/Biophysj.107.116590  0.367
2007 Deng L, Mariuzza RA. Recognition of self-peptide-MHC complexes by autoimmune T-cell receptors. Trends in Biochemical Sciences. 32: 500-8. PMID 17950605 DOI: 10.1016/J.Tibs.2007.08.007  0.461
2007 Velikovsky CA, Deng L, Chlewicki LK, Fernández MM, Kumar V, Mariuzza RA. Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family. Immunity. 27: 572-84. PMID 17950006 DOI: 10.1016/J.Immuni.2007.08.019  0.436
2007 Günther S, Varma AK, Moza B, Kasper KJ, Wyatt AW, Zhu P, Rahman AK, Li Y, Mariuzza RA, McCormick JK, Sundberg EJ. A novel loop domain in superantigens extends their T cell receptor recognition site. Journal of Molecular Biology. 371: 210-21. PMID 17560605 DOI: 10.1016/J.Jmb.2007.05.038  0.435
2007 Sundberg EJ, Deng L, Mariuzza RA. TCR recognition of peptide/MHC class II complexes and superantigens. Seminars in Immunology. 19: 262-71. PMID 17560120 DOI: 10.1016/J.Smim.2007.04.006  0.403
2007 Cho S, Wang Q, Swaminathan CP, Hesek D, Lee M, Boons GJ, Mobashery S, Mariuzza RA. Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proceedings of the National Academy of Sciences of the United States of America. 104: 8761-6. PMID 17502600 DOI: 10.1073/Pnas.0701453104  0.424
2007 Fernández MM, Bhattacharya S, De Marzi MC, Brown PH, Kerzic M, Schuck P, Mariuzza RA, Malchiodi EL. Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T-cell receptor Vbeta8.2. Proteins. 68: 389-402. PMID 17427250 DOI: 10.1002/Prot.21388  0.478
2007 Deng L, Langley RJ, Brown PH, Xu G, Teng L, Wang Q, Gonzales MI, Callender GG, Nishimura MI, Topalian SL, Mariuzza RA. Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor. Nature Immunology. 8: 398-408. PMID 17334368 DOI: 10.1038/Ni1447  0.486
2007 Guan R, Mariuzza RA. Peptidoglycan recognition proteins of the innate immune system. Trends in Microbiology. 15: 127-34. PMID 17275309 DOI: 10.1016/J.Tim.2007.01.006  0.37
2006 Dam J, Baber J, Grishaev A, Malchiodi EL, Schuck P, Bax A, Mariuzza RA. Variable dimerization of the Ly49A natural killer cell receptor results in differential engagement of its MHC class I ligand. Journal of Molecular Biology. 362: 102-13. PMID 16899255 DOI: 10.1016/J.Jmb.2006.07.005  0.441
2006 Fernández MM, Guan R, Swaminathan CP, Malchiodi EL, Mariuzza RA. Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule. The Journal of Biological Chemistry. 281: 25356-64. PMID 16829512 DOI: 10.1074/Jbc.M603969200  0.457
2006 Deng L, Mariuzza RA. Structural basis for recognition of MHC and MHC-like ligands by natural killer cell receptors. Seminars in Immunology. 18: 159-66. PMID 16737824 DOI: 10.1016/J.Smim.2006.03.004  0.44
2006 Guan R, Brown PH, Swaminathan CP, Roychowdhury A, Boons GJ, Mariuzza RA. Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria. Protein Science : a Publication of the Protein Society. 15: 1199-206. PMID 16641493 DOI: 10.1110/Ps.062077606  0.403
2006 Mariuzza RA. Multiple paths to multispecificity. Immunity. 24: 359-61. PMID 16618592 DOI: 10.1016/J.Immuni.2006.03.009  0.391
2006 Natarajan K, Hicks A, Mans J, Robinson H, Guan R, Mariuzza RA, Margulies DH. Crystal structure of the murine cytomegalovirus MHC-I homolog m144. Journal of Molecular Biology. 358: 157-71. PMID 16500675 DOI: 10.1016/J.Jmb.2006.01.068  0.357
2006 Sospedra M, Muraro PA, Stefanová I, Zhao Y, Chung K, Li Y, Giulianotti M, Simon R, Mariuzza R, Pinilla C, Martin R. Redundancy in antigen-presenting function of the HLA-DR and -DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotype. Journal of Immunology (Baltimore, Md. : 1950). 176: 1951-61. PMID 16424227 DOI: 10.4049/Jimmunol.176.3.1951  0.425
2006 Swaminathan CP, Brown PH, Roychowdhury A, Wang Q, Guan R, Silverman N, Goldman WE, Boons GJ, Mariuzza RA. Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proceedings of the National Academy of Sciences of the United States of America. 103: 684-9. PMID 16407132 DOI: 10.1073/Pnas.0507656103  0.409
2006 Fernández MM, De Marzi MC, Berguer P, Burzyn D, Langley RJ, Piazzon I, Mariuzza RA, Malchiodi EL. Binding of natural variants of staphylococcal superantigens SEG and SEI to TCR and MHC class II molecule. Molecular Immunology. 43: 927-38. PMID 16023209 DOI: 10.1016/J.Molimm.2005.06.029  0.442
2005 Cho S, Swaminathan CP, Yang J, Kerzic MC, Guan R, Kieke MC, Kranz DM, Mariuzza RA, Sundberg EJ. Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure (London, England : 1993). 13: 1775-87. PMID 16338406 DOI: 10.1016/J.Str.2005.08.015  0.377
2005 Kumar S, Roychowdhury A, Ember B, Wang Q, Guan R, Mariuzza RA, Boons GJ. Selective recognition of synthetic lysine and meso-diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition proteins I{alpha} and S. The Journal of Biological Chemistry. 280: 37005-12. PMID 16129677 DOI: 10.1074/Jbc.M506385200  0.301
2005 Li Y, Huang Y, Lue J, Quandt JA, Martin R, Mariuzza RA. Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule. The Embo Journal. 24: 2968-79. PMID 16079912 DOI: 10.1038/Sj.Emboj.7600771  0.435
2005 Deng L, Velikovsky CA, Swaminathan CP, Cho S, Mariuzza RA. Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1. Journal of Molecular Biology. 352: 1-10. PMID 16061254 DOI: 10.1016/J.Jmb.2005.06.072  0.472
2005 Ames JB, Vyas V, Lusin JD, Mariuzza R. NMR structure of the natural killer cell receptor 2B4 (CD244): implications for ligand recognition. Biochemistry. 44: 6416-23. PMID 15850375 DOI: 10.1021/Bi050139S  0.431
2005 Guan R, Roychowdury A, Ember B, Kumar S, Boons GJ, Mariuzza RA. Crystal structure of a peptidoglycan recognition protein (PGRP) in complex with a muramyl tripeptide from Gram-positive bacteria. Journal of Endotoxin Research. 11: 41-6. PMID 15826377 DOI: 10.1177/09680519050110010901  0.44
2005 Guan R, Wang Q, Sundberg EJ, Mariuzza RA. Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 A resolution. Journal of Molecular Biology. 347: 683-91. PMID 15769462 DOI: 10.1016/J.Jmb.2005.01.070  0.425
2005 Li Y, Huang Y, Swaminathan CP, Smith-Gill SJ, Mariuzza RA. Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces. Structure (London, England : 1993). 13: 297-307. PMID 15698573 DOI: 10.1016/J.Str.2004.12.012  0.391
2004 Guan R, Roychowdhury A, Ember B, Kumar S, Boons GJ, Mariuzza RA. Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 17168-73. PMID 15572450 DOI: 10.1073/Pnas.0407856101  0.44
2004 Swaminathan CP, Wais N, Vyas VV, Velikovsky CA, Moretta A, Moretta L, Biassoni R, Mariuzza RA, Dimasi N. Entropically assisted carbohydrate recognition by a natural killer cell-surface receptor. Chembiochem : a European Journal of Chemical Biology. 5: 1571-5. PMID 15515091 DOI: 10.1002/Cbic.200400130  0.341
2004 De Marzí MC, Fernández MM, Sundberg EJ, Molinero L, Zwirner NW, Llera AS, Mariuzza RA, Malchiodi EL. Cloning, expression and interaction of human T-cell receptors with the bacterial superantigen SSA. European Journal of Biochemistry / Febs. 271: 4075-83. PMID 15479236 DOI: 10.1111/J.1432-1033.2004.04345.X  0.44
2004 Guan R, Malchiodi EL, Wang Q, Schuck P, Mariuzza RA. Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha. The Journal of Biological Chemistry. 279: 31873-82. PMID 15140887 DOI: 10.1074/Jbc.M404920200  0.42
2004 Cho S, Velikovsky CA, Swaminathan CP, Houtman JC, Samelson LE, Mariuzza RA. Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads. The Embo Journal. 23: 1441-51. PMID 15029250 DOI: 10.1038/Sj.Emboj.7600168  0.414
2004 Dimasi N, Moretta A, Moretta L, Biassoni R, Mariuzza RA. Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1. Acta Crystallographica. Section D, Biological Crystallography. 60: 401-3. PMID 14747738 DOI: 10.1107/S0907444903028439  0.42
2003 Dam J, Guan R, Natarajan K, Dimasi N, Chlewicki LK, Kranz DM, Schuck P, Margulies DH, Mariuzza RA. Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nature Immunology. 4: 1213-22. PMID 14595439 DOI: 10.1038/Ni1006  0.451
2003 Yang J, Swaminathan CP, Huang Y, Guan R, Cho S, Kieke MC, Kranz DM, Mariuzza RA, Sundberg EJ. Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface. The Journal of Biological Chemistry. 278: 50412-21. PMID 14514664 DOI: 10.1074/Jbc.M306848200  0.403
2003 Dimasi N, Moretta L, Biassoni R, Mariuzza RA. Expression, crystallization and preliminary crystallographic analysis of the extracellular IgV-like domain of the human natural killer cell inhibitory receptor p75/AIRM1. Acta Crystallographica. Section D, Biological Crystallography. 59: 1856-8. PMID 14501137 DOI: 10.1107/S0907444903018146  0.35
2003 Sundberg EJ, Andersen PS, Schlievert PM, Karjalainen K, Mariuzza RA. Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation. Structure (London, England : 1993). 11: 1151-61. PMID 12962633 DOI: 10.1016/S0969-2126(03)00187-4  0.43
2003 Zavala-Ruiz Z, Sundberg EJ, Stone JD, DeOliveira DB, Chan IC, Svendsen J, Mariuzza RA, Stern LJ. Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1. The Journal of Biological Chemistry. 278: 44904-12. PMID 12952957 DOI: 10.1074/Jbc.M307652200  0.4
2003 McCormick JK, Tripp TJ, Llera AS, Sundberg EJ, Dinges MM, Mariuzza RA, Schlievert PM. Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes. Journal of Immunology (Baltimore, Md. : 1950). 171: 1385-92. PMID 12874229 DOI: 10.4049/Jimmunol.171.3.1385  0.41
2003 Dam J, Mariuzza RA. A growing family of natural killers. Structure (London, England : 1993). 11: 612-4. PMID 12791250 DOI: 10.1016/S0969-2126(03)00105-9  0.362
2003 Svitel J, Balbo A, Mariuzza RA, Gonzales NR, Schuck P. Combined affinity and rate constant distributions of ligand populations from experimental surface binding kinetics and equilibria. Biophysical Journal. 84: 4062-77. PMID 12770910 DOI: 10.1016/S0006-3495(03)75132-7  0.309
2003 Li Y, Li H, Yang F, Smith-Gill SJ, Mariuzza RA. X-ray snapshots of the maturation of an antibody response to a protein antigen. Nature Structural Biology. 10: 482-8. PMID 12740607 DOI: 10.1038/Nsb930  0.408
2003 Wang H, Lee HK, Bukowski JF, Li H, Mariuzza RA, Chen ZW, Nam KH, Morita CT. Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 3696-706. PMID 12646635 DOI: 10.4049/Jimmunol.170.7.3696  0.38
2003 Li Y, Urrutia M, Smith-Gill SJ, Mariuzza RA. Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen. Biochemistry. 42: 11-22. PMID 12515535 DOI: 10.1021/Bi020589+  0.444
2003 Sundberg EJ, Mariuzza RA. Antibody Structure and Recognition of Antigen Molecular Biology of B Cells. 491-509. DOI: 10.1016/B978-012053641-2/50032-0  0.328
2002 Sundberg EJ, Mariuzza RA. Molecular recognition in antibody-antigen complexes. Advances in Protein Chemistry. 61: 119-60. PMID 12461823 DOI: 10.1016/S0065-3233(02)61004-6  0.414
2002 Dimasi N, Sawicki MW, Reineck LA, Li Y, Natarajan K, Margulies DH, Mariuzza RA. Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family. Journal of Molecular Biology. 320: 573-85. PMID 12096910 DOI: 10.1016/S0022-2836(02)00498-9  0.465
2002 Sundberg EJ, Sawicki MW, Southwood S, Andersen PS, Sette A, Mariuzza RA. Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. Journal of Molecular Biology. 319: 449-61. PMID 12051920 DOI: 10.1016/S0022-2836(02)00370-4  0.446
2002 Sundberg EJ, Li H, Llera AS, McCormick JK, Tormo J, Schlievert PM, Karjalainen K, Mariuzza RA. Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes. Structure (London, England : 1993). 10: 687-99. PMID 12015151 DOI: 10.1016/S0969-2126(02)00759-1  0.464
2002 Natarajan K, Dimasi N, Wang J, Margulies DH, Mariuzza RA. MHC class I recognition by Ly49 natural killer cell receptors. Molecular Immunology. 38: 1023-7. PMID 11955594 DOI: 10.1016/S0161-5890(02)00031-7  0.425
2002 Andersen PS, Schuck P, Sundberg EJ, Geisler C, Karjalainen K, Mariuzza RA. Quantifying the energetics of cooperativity in a ternary protein complex. Biochemistry. 41: 5177-84. PMID 11955066 DOI: 10.1021/Bi0200209  0.36
2002 Natarajan K, Dimasi N, Wang J, Mariuzza RA, Margulies DH. Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination. Annual Review of Immunology. 20: 853-85. PMID 11861620 DOI: 10.1146/Annurev.Immunol.20.100301.064812  0.484
2002 Varela PF, Llera AS, Mariuzza RA, Tormo J. Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster. The Journal of Biological Chemistry. 277: 13229-36. PMID 11821393 DOI: 10.1074/Jbc.M110502200  0.355
2002 Sundberg EJ, Li Y, Mariuzza RA. So many ways of getting in the way: diversity in the molecular architecture of superantigen-dependent T-cell signaling complexes. Current Opinion in Immunology. 14: 36-44. PMID 11790531 DOI: 10.1016/S0952-7915(01)00296-5  0.474
2002 Wang J, Whitman MC, Natarajan K, Tormo J, Mariuzza RA, Margulies DH. Binding of the natural killer cell inhibitory receptor Ly49A to its major histocompatibility complex class I ligand. Crucial contacts include both H-2Dd AND beta 2-microglobulin. The Journal of Biological Chemistry. 277: 1433-42. PMID 11696552 DOI: 10.1074/Jbc.M110316200  0.357
2001 Andersen PS, Menné C, Mariuzza RA, Geisler C, Karjalainen K. A response calculus for immobilized T cell receptor ligands. The Journal of Biological Chemistry. 276: 49125-32. PMID 11592972 DOI: 10.1074/jbc.M109396200  0.307
2001 Sawicki MW, Dimasi N, Natarajan K, Wang J, Margulies DH, Mariuzza RA. Structural basis of MHC class I recognition by natural killer cell receptors Immunological Reviews. 181: 52-65. PMID 11513152 DOI: 10.1034/J.1600-065X.2001.1810104.X  0.429
2001 Morita CT, Lee HK, Wang H, Li H, Mariuzza RA, Tanaka Y. Structural features of nonpeptide prenyl pyrophosphates that determine their antigenicity for human gamma delta T cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 36-41. PMID 11418629 DOI: 10.4049/Jimmunol.167.1.36  0.442
2001 Andersen PS, Geisler C, Buus S, Mariuzza RA, Karjalainen K. Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens. The Journal of Biological Chemistry. 276: 33452-7. PMID 11397806 DOI: 10.1074/jbc.M103750200  0.367
2001 Kieke MC, Sundberg E, Shusta EV, Mariuzza RA, Wittrup KD, Kranz DM. High affinity T cell receptors from yeast display libraries block T cell activation by superantigens. Journal of Molecular Biology. 307: 1305-15. PMID 11292343 DOI: 10.1006/Jmbi.2001.4560  0.47
2001 Morita CT, Li H, Lamphear JG, Rich RR, Fraser JD, Mariuzza RA, Lee HK. Superantigen recognition by γδ T cells: SEA recognition site for human Vγ2 T cell receptors Immunity. 14: 331-344. PMID 11290341 DOI: 10.1016/S1074-7613(01)00113-3  0.46
2001 Li Y, Li H, Dimasi N, McCormick JK, Martin R, Schuck P, Schlievert PM, Mariuzza RA. Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II. Immunity. 14: 93-104. PMID 11163233 DOI: 10.1016/S1074-7613(01)00092-9  0.438
2000 Doo Hyun Chung, Natarajan K, Boyd LF, Tormo J, Mariuzza RA, Yokoyama WM, Margulies DH. Mapping the ligand of the NK inhibitory receptor Ly49A on living cells Journal of Immunology. 165: 6922-6932. PMID 11120818 DOI: 10.4049/Jimmunol.165.12.6922  0.387
2000 Morita CT, Mariuzza RA, Brenner MB. Antigen recognition by human γδ T cells: Pattern recognition by the adaptive immune system Springer Seminars in Immunopathology. 22: 191-217. PMID 11116953 DOI: 10.1007/S002810000042  0.373
2000 Sundberg EJ, Urrutia M, Braden BC, Isern J, Tsuchiya D, Fields BA, Malchiodi EL, Tormo J, Schwarz FP, Mariuzza RA. Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface. Biochemistry. 39: 15375-87. PMID 11112523 DOI: 10.1021/Bi000704L  0.389
2000 Natarajan K, Sawicki MW, Margulies DH, Mariuzza RA. Crystal structure of human CD69: A C-type lectin-like activation marker of hematopoietic cells Biochemistry. 39: 14779-14786. PMID 11101293 DOI: 10.1021/Bi0018180  0.443
2000 Li Y, Li H, Martin R, Mariuzza RA. Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins Journal of Molecular Biology. 304: 177-188. PMID 11080454 DOI: 10.1006/Jmbi.2000.4198  0.458
2000 Sundberg EJ, Mariuzza RA. Luxury accomodation: The expanding role of structural plasticity in protein-protein interaction Structure. 8. PMID 10903952 DOI: 10.1016/S0969-2126(00)00167-2  0.33
2000 Li Y, Li H, Smith-Gill SJ, Mariuzza RA. Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63 Biochemistry. 39: 6296-6309. PMID 10828942 DOI: 10.1021/Bi000054L  0.441
2000 Churchill HR, Andersen PS, Parke EA, Mariuzza RA, Kranz DM. Mapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis. The Journal of Experimental Medicine. 191: 835-46. PMID 10704464 DOI: 10.1084/Jem.191.5.835  0.46
2000 Tormo J, Natarajan K, Margulies DH, Mariuzza RA. Self recognition in the immune system: structure of a Natural Killer receptor bound to its MHC class I ligand Acta Crystallographica Section a Foundations of Crystallography. 56: s98-s98. DOI: 10.1107/S0108767300022674  0.397
1999 Natarajan K, Li H, Mariuzza RA, Margulies DH. MHC class I molecules, structure and function Reviews in Immunogenetics. 1: 32-46. PMID 11256571  0.346
1999 Tormo J, Natarajan K, Margulles DH, Mariuzza RA. Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand Nature. 402: 623-631. PMID 10604468 DOI: 10.1038/45170  0.46
1999 Li H, Llera A, Malchiodi EL, Mariuzza RA. The structural basis of T cell activation by superantigens Annual Review of Immunology. 17: 435-466. PMID 10358765 DOI: 10.1146/Annurev.Immunol.17.1.435  0.489
1999 Andersen PS, Lavoie PM, Sékaly RP, Churchill H, Kranz DM, Schlievert PM, Karjalainen K, Mariuzza RA. Role of the T cell receptor α chain in stabilizing TCR-superantigen- MHC class II complexes Immunity. 10: 473-483. PMID 10229190 DOI: 10.1016/S1074-7613(00)80047-3  0.449
1998 Hongmin L, Llera A, Tsuchiya D, Leder L, Ysern X, Schlievert PM, Karjalainen K, Mariuzza RA. Three-dimensional structure of the complex between a T cell receptor β chain and the superantigen staphylococcal enterotoxin B Immunity. 9: 807-816. PMID 9881971 DOI: 10.1016/S1074-7613(00)80646-9  0.501
1998 Li H, Natarajan K, Malchiodi EL, Margulies DH, Mariuzza RA. Three-dimensional structure of H-2D(d) complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120 Journal of Molecular Biology. 283: 179-191. PMID 9761682 DOI: 10.1006/Jmbi.1998.2091  0.375
1998 Li H, Llera A, Mariuzza RA. Structure-function studies of T-cell receptor-superantigen interactions Immunological Reviews. 163: 177-186. PMID 9700510 DOI: 10.1111/J.1600-065X.1998.Tb01196.X  0.536
1998 Braden BC, Goldman ER, Mariuzza RA, Poljak RJ. Anatomy of an antibody molecule: structure, kinetics, thermodynamics and mutational studies of the antilysozyme antibody D1.3. Immunological Reviews. 163: 45-57. PMID 9700501 DOI: 10.1111/J.1600-065X.1998.Tb01187.X  0.425
1998 Ysern X, Li H, Mariuzza RA. Imperfect interfaces Nature Structural Biology. 5: 412-414. PMID 9628472 DOI: 10.1038/nsb0698-412  0.409
1998 Dall'Acqua W, Goldman ER, Lin W, Teng C, Tsuchiya D, Li H, Ysern X, Braden BC, Li Y, Smith-Gill SJ, Mariuzza RA. A mutational analysis of binding interactions in an antigen-antibody protein-protein complex. Biochemistry. 37: 7981-91. PMID 9609690 DOI: 10.1021/Bi980148J  0.38
1998 Leder L, Llera A, Lavoie PM, Lebedeva MI, Li H, Sékaly RP, Bohach GA, Gahr PJ, Schlievert PM, Karjalainen K, Mariuzza RA. A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor β chain and major histocompatibility complex class II Journal of Experimental Medicine. 187: 823-833. PMID 9500785 DOI: 10.1084/Jem.187.6.823  0.483
1998 Li H, Lebedeva MI, Llera AS, Fields BA, Brenner MB, Mariuzza RA. Structure of the Vδ domain of a human γδ T-cell antigen receptor Nature. 391: 502-506. PMID 9461220 DOI: 10.1038/35172  0.536
1997 Li H, Lebedeva MI, Ward SE, Mariuzza RA. Dual conformations of a T cell receptor Vα homodimer: Implications for variability in VαVβ domain association Journal of Molecular Biology. 269: 385-394. PMID 9199407 DOI: 10.1006/Jmbi.1997.1047  0.409
1997 Goldman ER, Dall'Acqua W, Braden BC, Mariuzza RA. Analysis of binding interactions in an idiotope-antiidiotope protein-protein complex by double mutant cycles. Biochemistry. 36: 49-56. PMID 8993317 DOI: 10.1021/Bi961769K  0.38
1996 Lebedeva MI, Fields BA, Spits H, Panchamoorthy G, Brenner MB, Mariuzza RA. Cloning, expression, and crystallization of the Vδ domain of a human γδ T-cell receptor Protein Science. 5: 2638-2642. PMID 8976572 DOI: 10.1002/Pro.5560051226  0.485
1996 Fields BA, Goldbaum FA, Acqua WD, Malchiodi EL, Cauerhff A, Schwarz FP, Ysern X, Poljak RJ, Mariuzza RA. Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme Biochemistry. 35: 15494-15503. PMID 8952503 DOI: 10.1021/Bi961709E  0.375
1996 Braden BC, Fields BA, Ysern X, Dall'Acqua W, Goldbaum FA, Poljak RJ, Mariuzza RA. Crystal structure of an Fv-Fv idiotope - Anti-idiotope complex at 1.9 Å resolution Journal of Molecular Biology. 264: 137-151. PMID 8950273 DOI: 10.1006/Jmbi.1996.0629  0.402
1996 Fields BA, Malchiodi EL, Li H, Ysern X, Stauffacher CV, Schlievert PM, Karjalainen K, Mariuzza RA. Crystal structure of a T-cell receptor β-chain complexed with a superantigen Nature. 384: 188-192. PMID 8906797 DOI: 10.1038/384188A0  0.503
1996 Fields BA, Mariuzza RA. Structure and function of the T-cell receptor: Insights from X-ray crystallography Immunology Today. 17: 330-336. PMID 8763819 DOI: 10.1016/0167-5699(96)10020-7  0.463
1996 Goldbaum FA, Schwarz FP, Eisenstein E, Cauerhff A, Mariuzza RA, Poljak RJ. The effect of water activity on the association constant and the enthalpy of reaction between lysozyme and the specific antibodies D1.3 and D44.1 Journal of Molecular Recognition. 9: 6-12. PMID 8723314 DOI: 10.1002/(Sici)1099-1352(199601)9:1<6::Aid-Jmr240>3.0.Co;2-V  0.351
1996 Bentley GA, Mariuzza RA. The structure of the T cell antigen receptor Annual Review of Immunology. 14: 563-590. PMID 8717525 DOI: 10.1146/Annurev.Immunol.14.1.563  0.485
1996 Dall'Acqua W, Goldman ER, Eisenstein E, Mariuzza RA. A mutational analysis of the binding of two different proteins to the same antibody. Biochemistry. 35: 9667-76. PMID 8703938 DOI: 10.1021/Bi960819I  0.395
1996 Braden BC, Fields BA, Ysern X, Goldbaum FA, Dall'Acqua W, Schwarz FP, Poljak RJ, Mariuzza RA. Crystal structure of the complex of the variable domain of antibody D1.3 and turkey egg white lysozyme: A novel conformational change in antibody CDR-L3 selects for antigen Journal of Molecular Biology. 257: 889-894. PMID 8632472 DOI: 10.1006/Jmbi.1996.0209  0.405
1996 Li H, Lebedeva MI, Ward ES, Mariuzza RA. Crystal structure of a CDR3 mutant of a T cell antigen receptor Va domain Acta Crystallographica Section a Foundations of Crystallography. 52: C221-C221. DOI: 10.1107/S0108767396090514  0.439
1996 Mariuzza RA, Li H, Malchiodi EL, Ysern X, Stauffacher CV, Schlievert PM, Karjalainan K, Fields BA. Structure of a superantigen T-cell receptor chain complex Acta Crystallographica Section a Foundations of Crystallography. 52: C581-C581. DOI: 10.1107/S0108767396076362  0.425
1995 Bentley GA, Boulot G, Mariuzza RA. The structure of the antigen-binding site of immunoglobulins and T-cell receptors Research in Immunology. 146: 277-290. PMID 8577989 DOI: 10.1016/0923-2494(96)80262-8  0.316
1995 Fields BA, Ober B, Malchiodi EL, Lebedeva MI, Braden BC, Ysern X, Kim JK, Shao X, Ward ES, Mariuzza RA. Crystal structure of the Vα domain of a T cell antigen receptor Science. 270: 1821-1824. PMID 8525376 DOI: 10.1126/Science.270.5243.1821  0.503
1995 Schwarz FP, Tello D, Goldbaum FA, Mariuzza RA, Poljak RJ. Thermodynamics of antigen-antibody binding using specific anti-lysozyme antibodies European Journal of Biochemistry. 228: 388-394. PMID 7705353 DOI: 10.1111/J.1432-1033.1995.0388N.X  0.362
1995 Bentley GA, Boulot G, Karjalainen K, Mariuzza RA. Crystal structure of the β chain of a T cell antigen receptor Science. 267: 1984-1987. PMID 7701320 DOI: 10.1126/Science.7701320  0.448
1995 Braden BC, Dall'Acqua W, Eisenstein E, Fields BA, Goldbaum FA, Malchiodi EL, Mariuzza RA, Schwarz FP, Ysern X, Poljak RJ. Protein motion and lock and key complementarity in antigen-antibody reactions Pharmaceutica Acta Helvetiae. 69: 225-230. PMID 7651966 DOI: 10.1016/0031-6865(94)00046-X  0.391
1995 Fields BA, Goldbaum FA, Ysern X, Poijak RJ, Mariuzza RA. Molecular basis of antigen mimicry by an anti-idiotope Nature. 374: 739-742. PMID 7536303 DOI: 10.1038/374739A0  0.378
1995 Malchiodi EL, Eisenstein E, Fields BA, Ohlendorf DH, Schlievert PM, Karjalainen K, Mariuzza RA. Superantigen binding to a T cell receptor γ chain of known three-dimensional structure Journal of Experimental Medicine. 182: 1833-1845. PMID 7500029 DOI: 10.1084/Jem.182.6.1833  0.459
1995 Braden BC, Cauerhff A, Dall'Acqua W, Fields BA, Goldbaum FA, Malchiodi EL, Mariuzza RA, Poljak RJ, Schwarz FP, Ysern X, Bhat TN. Structure and thermodynamics of antigen recognition by antibodies Annals of the New York Academy of Sciences. 764: 315-327. PMID 7486542 DOI: 10.1111/J.1749-6632.1995.Tb55843.X  0.395
1994 Bhat TN, Bentley GA, Boulot G, Greene MI, Tello D, Dall'Acqua W, Souchon H, Schwarz FP, Mariuzza RA, Poljak RJ. Bound water molecules and conformational stabilization help mediate an antigen-antibody association Proceedings of the National Academy of Sciences of the United States of America. 91: 1089-1093. PMID 8302837 DOI: 10.1073/Pnas.91.3.1089  0.418
1994 Ysern X, Fields BA, Bhat TN, Goldbaum FA, Dall'Acqua W, Schwarz FP, Poljak RJ, Mariuzza RA. Solvent rearrangement in an antigen-antibody interface introduced by site-directed mutagenesis of the antibody combining site Journal of Molecular Biology. 238: 496-500. PMID 8176740 DOI: 10.1006/Jmbi.1994.1309  0.43
1994 Goldbaum FA, Fields BA, Cauerhff A, Ysern X, Houdusse A, Eisele JL, Poljak RJ, Mariuzza RA. Crystallization and preliminary x-ray diffraction study of an idiotope-anti-idiotope Fv-Fv complex Journal of Molecular Biology. 241: 739-743. PMID 8071997 DOI: 10.1006/Jmbi.1994.1549  0.365
1994 Mariuzza RA, Poljak RJ, Schwarz FP. The energetics of antigen-antibody binding Research in Immunology. 145: 70-72. PMID 8008972 DOI: 10.1016/S0923-2494(94)80048-0  0.352
1994 Tello D, Eisenstein E, Schwarz FP, Goldbaum FA, Fields BA, Mariuzza RA, Poljak RJ. Structural and physicochemical analysis of the reaction between the anti-lysozyme antibody D1.3 and the anti-idiotopic antibodies E225 and E5.2 Journal of Molecular Recognition. 7: 57-62. PMID 7986568 DOI: 10.1002/Jmr.300070108  0.346
1994 Fields BA, Ysern X, Poljak RJ, Shao X, Ward ES, Mariuzza RA. Crystallization and preliminary X-ray diffraction study of a bacterially produced T-cell antigen receptor Vα domain Journal of Molecular Biology. 239: 339-341. PMID 7515113 DOI: 10.1006/Jmbi.1994.1373  0.433
1993 Mariuzza RA, PoIjak RJ. The basics of binding: mechanisms of antigen recognition and mimicry by antibodies Current Opinion in Immunology. 5: 50-55. PMID 8452674 DOI: 10.1016/0952-7915(93)90080-C  0.427
1993 Alcover A, Hervé F, Boursier JP, Spagnoli G, Olive D, Mariuzza RA, Acuto O. A soluble form of the human CD8 alpha chain expressed in the baculovirus system: biochemical characterization and binding to MHC class I Molecular Immunology. 30: 55-67. PMID 8417375 DOI: 10.1016/0161-5890(93)90426-C  0.425
1993 Tello D, Goldbaum FA, Mariuzza RA, Ysern X, Schwarz FP, Poljak RJ. Three-dimensional structure and thermodynamics of antigen binding by anti-lysozyme antibodies Biochemical Society Transactions. 21: 943-946. PMID 8132099 DOI: 10.1042/Bst0210943  0.411
1992 Boitel B, Ermonval M, Panina-Bordignon P, Mariuzza RA, Lanzavecchia A, Acuto O. Preferential Vβ gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: Evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition Journal of Experimental Medicine. 175: 765-777. PMID 1371303 DOI: 10.1084/Jem.175.3.765  0.433
1991 Fischmann TO, Bentley GA, Bhat TN, Boulot G, Mariuzza RA, Phillips SEV, Tello D, Poljak RJ. Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-Å resolution Journal of Biological Chemistry. 266: 12915-12920. PMID 1712773 DOI: 10.2210/Pdb1Fdl/Pdb  0.427
1990 Bismuth G, Gouy H, Mariuzza RA, Vaquero C, Theodorou I, Debre P. A human TCR-Ig chimeric protein used to generate a TCR α chain variable region-specific mAb Molecular Immunology. 27: 1127-1136. PMID 2147229 DOI: 10.1016/0161-5890(90)90101-5  0.463
1990 Alzari PM, Spinelli S, Mariuzza RA, Boulot G, Poljak RJ, Jarvis JM, Milstein C. Three-dimensional structure determination of an anti-2-phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response. The Embo Journal. 9: 3807-14. PMID 2123450 DOI: 10.1002/J.1460-2075.1990.Tb07598.X  0.391
1990 Tello D, Spinelli S, Souchon H, Saul FA, Riottot MM, Mariuzza RA, Lascombe MB, Houdusse A, Eiselé JL, Fischmann T, Chitarra V, Boulot G, Bhat TN, Bentley GA, Alzari PM, et al. Three-dimensional structure and antigen binding specificity of antibodies Biochimie. 72: 507-512. PMID 1704260 DOI: 10.1016/0300-9084(90)90114-V  0.418
1989 Chitarra-Guillon V, Souchon H, Boulot G, Riottot MM, Mariuzza R, Tello D, Poljak RJ. Crystallization and preliminary X-ray diffraction studies of antigen--antibody complexes. Biochimie. 70: 1045-52. PMID 3147699 DOI: 10.1016/0300-9084(88)90267-2  0.372
1989 Bentley GA, Alzari PM, Amit AG, Boulot G, Guillon-Chitarra V, Fischmann T, Lascombe MB, Mariuzza RA, Poljak RJ, Riottot MM. Studies of structure and specificity of some antigen-antibody complexes Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 323: 487-494. PMID 2569206 DOI: 10.1098/Rstb.1989.0026  0.421
1989 Mariuzza RA, Winter G. Secretion of a homodimeric V(α)C()κ)T-cell receptor-immunoglobulin chimeric protein Journal of Biological Chemistry. 264: 7310-7316. PMID 2523393  0.3
1988 Boulot G, Guillon V, Mariuzza RA, Poljak RJ, Riottot MM, Souchon H, Spinelli S, Tello D. Crystallization of antibody fragments and their complexes with antigen Journal of Crystal Growth. 90: 213-221. DOI: 10.1016/0022-0248(88)90318-1  0.387
1987 Mariuzza RA, Phillips SE, Poljak RJ. The structural basis of antigen-antibody recognition Annual Review of Biophysics and Biophysical Chemistry. 16: 139-159. PMID 2439094  0.34
1987 Amit AG, Mariuzza RA, Phillips SEV, Poljak RJ. Antibody–antigen recognition: the structure of a Fab–lysozyme complex Acta Crystallographica Section a Foundations of Crystallography. 43: C17-C18. DOI: 10.1107/S0108767387085064  0.325
1986 Chothia C, Lesk AM, Levitt M, Amit AG, Mariuzza RA, Phillips SE, Poljak RJ. The predicted structure of immunoglobulin D1.3 and its comparison with the crystal structure. Science (New York, N.Y.). 233: 755-8. PMID 3090684 DOI: 10.1126/Science.3090684  0.4
1986 Amit AG, Mariuzza RA, Phillips SEV, Poljak RJ. Three-dimensional structure of an antigen-antibody complex at 2.8 Å resolution Science. 233: 747-753. PMID 2426778 DOI: 10.1126/Science.2426778  0.421
1985 Amit AG, Boulot G, Comarmond MB, Harper M, Mariuzza RA, Phillips SE, Saludjian P, Saul FA, Souchon H, Tougard P. X-ray diffraction studies of an anti-azophenylarsonate antibody and of an antigen-antibody complex Annales De L'Institut Pasteur - Immunology. 136: 121-129. PMID 3994300 DOI: 10.1016/S0769-2625(85)80044-1  0.368
1985 Amit AG, Mariuzza RA, Phillips SEV, Poljak RJ. Three-dimensional structure of an antigen-antibody complex at 6 Å resolution Nature. 313: 156-158. PMID 3965976 DOI: 10.1038/313156A0  0.439
1984 Amit AG, Boulot G, Harper M, Jankovic D, Le Guern A, Mariuzza RA, Mazié JC, Phillips SEV, Poljak RJ. Crystallographic study of the complex between the Fab fragment of monoclonal anti-lysozyme antibody and its antigen Acta Crystallographica Section a Foundations of Crystallography. 40: C44-C44. DOI: 10.1107/S0108767384098445  0.366
1983 Amit AG, Harper MM, Mariuzza RA, Saludjian P, Poljak RJ, Lamoyi E, Nisonoff A. Preliminary crystallographic study of the Fab fragment of a monoclonal anti-phenylarsonate antibody. Journal of Molecular Biology. 165: 415-7. PMID 6842607 DOI: 10.1016/S0022-2836(83)80266-6  0.355
1983 Mariuzza RA, Jankovic DL, Boulot G, Amit AG, Saludjian P, Le Guern A, Mazié JC, Poljak RJ. Preliminary crystallographic study of the complex between the Fab fragment of a monoclonal anti-lysozyme antibody and its antigen Journal of Molecular Biology. 170: 1055-1058. PMID 6644814 DOI: 10.1016/S0022-2836(83)80206-X  0.369
1983 Amit AG, Mariuzza RA, Saludjian P, Poljak RJ, Lamoyi E, Nisonoff A. Preliminary crystallographic study of the fab fragment of a monoclonal anti-phenylarsonate antibody possessing a major idiotypic specificity Journal of Molecular Biology. 169: 637-638. PMID 6620388 DOI: 10.1016/S0022-2836(83)80068-0  0.349
1983 Mariuzza RA, Poljak RJ, Mihaesco C, Mihaesco E. Crystals of the human heavy chain disease protein riv and human Fc fragment are isomorphous: Further evidence for conformational flexibility in the hinge region of immunoglobulins Journal of Molecular Biology. 165: 559-561. PMID 6405046 DOI: 10.1016/S0022-2836(83)80220-4  0.307
Show low-probability matches.