Year |
Citation |
Score |
2017 |
Guerra D, Chapiro SM, Pratelli R, Yu S, Jia W, Leary J, Pilot G, Callis J. Control of amino acid homeostasis by a ubiquitin ligase-coactivator protein complex. The Journal of Biological Chemistry. PMID 28100770 DOI: 10.1074/Jbc.M116.766469 |
0.308 |
|
2016 |
Sogi KM, Holsclaw CM, Fragiadakis GK, Nomura DK, Leary JA, Bertozzi CR. Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis. Acs Infectious Diseases. 2: 800-806. PMID 27933784 DOI: 10.1021/Acsinfecdis.6B00106 |
0.776 |
|
2016 |
Miller RL, Guimond SE, Shivkumar M, Blocksidge J, Austin J, Leary JA, Turnbull JE. Heparin isomeric oligosaccharide separation using volatile salt strong anion exchange chromatography. Analytical Chemistry. PMID 27801575 DOI: 10.1021/Acs.Analchem.6B02801 |
0.407 |
|
2016 |
Miller RL, Dykstra AB, Wei W, Holsclaw CM, Turnbull JE, Leary JA. Enrichment of two isomeric heparin oligosaccharides exhibiting different affinities towards MCP-1. Analytical Chemistry. PMID 27801570 DOI: 10.1021/Acs.Analchem.6B02803 |
0.801 |
|
2015 |
Leary JA. Structure from Splatter. Acs Central Science. 1: 475-6. PMID 27163012 DOI: 10.1021/Acscentsci.5B00390 |
0.339 |
|
2015 |
Leary JA, Miller RL, Wei W, Schwörer R, Zubkova OV, Tyler PC, Turnbull JE. Composition, sequencing and ion mobility mass spectrometry of heparan sulfate-like octasaccharide isomers differing in glucuronic and iduronic acid content. European Journal of Mass Spectrometry (Chichester, England). 21: 245-54. PMID 26307704 DOI: 10.1255/Ejms.1337 |
0.426 |
|
2015 |
Crowder ME, Flynn JR, McNally KP, Cortes DB, Price KL, Kuehnert PA, Panzica MT, Andaya A, Leary JA, McNally FJ. Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans. Molecular Biology of the Cell. 26: 3030-46. PMID 26133383 DOI: 10.1091/Mbc.E15-05-0290 |
0.663 |
|
2015 |
Touchette MH, Holsclaw CM, Previti ML, Solomon VC, Leary JA, Bertozzi CR, Seeliger JC. The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis. Journal of Bacteriology. 197: 201-10. PMID 25331437 DOI: 10.1128/Jb.02015-14 |
0.786 |
|
2014 |
Sabol JK, Wei W, López-Hoyos M, Seo Y, Andaya A, Leary JA. Heparan sulfate differences in rheumatoid arthritis versus healthy sera. Matrix Biology : Journal of the International Society For Matrix Biology. 40: 54-61. PMID 25217862 DOI: 10.1016/J.Matbio.2014.08.016 |
0.734 |
|
2014 |
Andaya A, Villa N, Jia W, Fraser CS, Leary JA. Phosphorylation stoichiometries of human eukaryotic initiation factors. International Journal of Molecular Sciences. 15: 11523-38. PMID 24979134 DOI: 10.3390/Ijms150711523 |
0.704 |
|
2013 |
Seo Y, Andaya A, Bleiholder C, Leary JA. Differentiation of CC vs CXC chemokine dimers with GAG octasaccharide binding partners: an ion mobility mass spectrometry approach. Journal of the American Chemical Society. 135: 4325-32. PMID 23418647 DOI: 10.1021/Ja310915M |
0.768 |
|
2013 |
Leary JA. Mass Spectrometric Characterization of Protein:Carbohydrate Non Covalent Complexes: What is Fact and What is Fiction Biophysical Journal. 104: 355a. DOI: 10.1016/J.Bpj.2012.11.1974 |
0.385 |
|
2012 |
Swarts BM, Holsclaw CM, Jewett JC, Alber M, Fox DM, Siegrist MS, Leary JA, Kalscheuer R, Bertozzi CR. Probing the mycobacterial trehalome with bioorthogonal chemistry. Journal of the American Chemical Society. 134: 16123-6. PMID 22978752 DOI: 10.1021/Ja3062419 |
0.765 |
|
2012 |
Gilmore SA, Schelle MW, Holsclaw CM, Leigh CD, Jain M, Cox JS, Leary JA, Bertozzi CR. Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages. Acs Chemical Biology. 7: 863-70. PMID 22360425 DOI: 10.1021/Cb200311S |
0.772 |
|
2012 |
Jia W, Andaya A, Leary JA. Novel mass spectrometric method for phosphorylation quantification using cerium oxide nanoparticles and tandem mass tags. Analytical Chemistry. 84: 2466-73. PMID 22304650 DOI: 10.1021/Ac203248S |
0.699 |
|
2012 |
Seo Y, Andaya A, Leary JA. Preparation, separation, and conformational analysis of differentially sulfated heparin octasaccharide isomers using ion mobility mass spectrometry. Analytical Chemistry. 84: 2416-23. PMID 22283665 DOI: 10.1021/Ac203190K |
0.776 |
|
2012 |
Seeliger JC, Holsclaw CM, Schelle MW, Botyanszki Z, Gilmore SA, Tully SE, Niederweis M, Cravatt BF, Leary JA, Bertozzi CR. Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 287: 7990-8000. PMID 22194604 DOI: 10.1074/Jbc.M111.315473 |
0.782 |
|
2011 |
Holsclaw CM, Muse WB, Carroll KS, Leary JA. Mass Spectrometric Analysis of Mycothiol levels in Wild-Type and Mycothiol Disulfide Reductase Mutant Mycobacterium smegmatis. International Journal of Mass Spectrometry. 305: 151-156. PMID 21857792 DOI: 10.1016/J.Ijms.2010.10.027 |
0.791 |
|
2011 |
Andaya A, Jia W, Sokabe M, Fraser CS, Hershey JW, Leary JA. Phosphorylation of human eukaryotic initiation factor 2γ: novel site identification and targeted PKC involvement. Journal of Proteome Research. 10: 4613-23. PMID 21854064 DOI: 10.1021/Pr200429Y |
0.696 |
|
2011 |
Seo Y, Schenauer MR, Leary JA. Biologically Relevant Metal-Cation Binding Induces Conformational Changes in Heparin Oligosaccharides as Measured by Ion Mobility Mass Spectrometry. International Journal of Mass Spectrometry. 303: 191-198. PMID 21731426 DOI: 10.1016/J.Ijms.2011.02.003 |
0.798 |
|
2010 |
Cai Q, Todorovic A, Andaya A, Gao J, Leary JA, Cate JH. Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit. Journal of Molecular Biology. 403: 185-96. PMID 20816988 DOI: 10.1016/J.Jmb.2010.07.054 |
0.685 |
|
2010 |
Jen CH, Leary JA. A competitive binding study of chemokine, sulfated receptor, and glycosaminoglycan interactions by nano-electrospray ionization mass spectrometry. Analytical Biochemistry. 407: 134-40. PMID 20696123 DOI: 10.1016/J.Ab.2010.08.005 |
0.683 |
|
2010 |
Danan LM, Yu Z, Ludden PJ, Jia W, Moore KL, Leary JA. Catalytic mechanism of golgi-resident human tyrosylprotein sulfotransferase-2: A mass spectrometry approach Journal of the American Society For Mass Spectrometry. 21: 1633-1642. PMID 20462768 DOI: 10.1016/j.jasms.2010.03.037 |
0.794 |
|
2010 |
Danan LM, Yu Z, Hoffhines AJ, Moore KL, Leary JA. Erratum to: Erratum Journal of the American Society For Mass Spectrometry. 21: 1470-1470. DOI: 10.1016/J.Jasms.2010.04.008 |
0.725 |
|
2009 |
Schenauer MR, Leary JA. An Ion Mobility-Mass Spectrometry Investigation of Monocyte Chemoattractant Protein-1. International Journal of Mass Spectrometry. 287: 70-76. PMID 20160907 DOI: 10.1016/J.Ijms.2009.02.023 |
0.801 |
|
2009 |
Schenauer MR, Meissen JK, Seo Y, Ames JB, Leary JA. Heparan sulfate separation, sequencing, and isomeric differentiation: ion mobility spectrometry reveals specific iduronic and glucuronic acid-containing hexasaccharides. Analytical Chemistry. 81: 10179-85. PMID 19925012 DOI: 10.1021/Ac902186H |
0.803 |
|
2009 |
Pukala TL, Ruotolo BT, Zhou M, Politis A, Stefanescu R, Leary JA, Robinson CV. Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements. Structure (London, England : 1993). 17: 1235-43. PMID 19748344 DOI: 10.1016/J.Str.2009.07.013 |
0.382 |
|
2009 |
Leary JA, Schenauer MR, Stefanescu R, Andaya A, Ruotolo BT, Robinson CV, Thalassinos K, Scrivens JH, Sokabe M, Hershey JW. Methodology for measuring conformation of solvent-disrupted protein subunits using T-WAVE ion mobility MS: an investigation into eukaryotic initiation factors. Journal of the American Society For Mass Spectrometry. 20: 1699-706. PMID 19564121 DOI: 10.1016/J.Jasms.2009.05.003 |
0.781 |
|
2009 |
Jen CH, Moore KL, Leary JA. Pattern and temporal sequence of sulfation of CCR5 N-terminal peptides by tyrosylprotein sulfotransferase-2: an assessment of the effects of N-terminal residues. Biochemistry. 48: 5332-8. PMID 19402700 DOI: 10.1021/Bi900285C |
0.659 |
|
2009 |
Hatzios SK, Schelle MW, Holsclaw CM, Behrens CR, Botyanszki Z, Lin FL, Carlson BL, Kumar P, Leary JA, Bertozzi CR. PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 284: 12745-51. PMID 19276083 DOI: 10.1074/Jbc.M809088200 |
0.781 |
|
2009 |
Hoffhines AJ, Jen CH, Leary JA, Moore KL. Tyrosylprotein sulfotransferase-2 expression is required for sulfation of RNase 9 and Mfge8 in vivo. The Journal of Biological Chemistry. 284: 3096-105. PMID 19047058 DOI: 10.1074/Jbc.M808434200 |
0.668 |
|
2009 |
Shaffer JF, Jia W, Leary JA, Harris SP. PKA Phosphorylates Serine 307 of Murine Cardiac Myosin Binding Protein-C In Vitro Biophysical Journal. 96: 500a. DOI: 10.1016/J.Bpj.2008.12.2580 |
0.312 |
|
2008 |
Holsclaw CM, Sogi KM, Gilmore SA, Schelle MW, Leavell MD, Bertozzi CR, Leary JA. Structural characterization of a novel sulfated menaquinone produced by stf3 from Mycobacterium tuberculosis. Acs Chemical Biology. 3: 619-24. PMID 18928249 DOI: 10.1021/Cb800145R |
0.797 |
|
2008 |
Danan LM, Yu Z, Hoffhines AJ, Moore KL, Leary JA. Mass spectrometric kinetic analysis of human tyrosylprotein sulfotransferase-1 and -2. Journal of the American Society For Mass Spectrometry. 19: 1459-66. PMID 18672380 DOI: 10.1016/j.jasms.2008.06.021 |
0.797 |
|
2008 |
Zhou M, Sandercock AM, Fraser CS, Ridlova G, Stephens E, Schenauer MR, Yokoi-Fong T, Barsky D, Leary JA, Hershey JW, Doudna JA, Robinson CV. Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. Proceedings of the National Academy of Sciences of the United States of America. 105: 18139-44. PMID 18599441 DOI: 10.1073/Pnas.0801313105 |
0.788 |
|
2008 |
Baidoo EE, Benke PI, Neusüss C, Pelzing M, Kruppa G, Leary JA, Keasling JD. Capillary electrophoresis-fourier transform ion cyclotron resonance mass spectrometry for the identification of cationic metabolites via a pH-mediated stacking-transient isotachophoretic method. Analytical Chemistry. 80: 3112-22. PMID 18384203 DOI: 10.1021/Ac800007Q |
0.402 |
|
2008 |
Bowers JJ, Hodges BDM, Saad OM, Leary JA, McLuckey SA. Proton hydrates as soft ion/ion proton transfer reagents for multiply deprotonated biomolecules International Journal of Mass Spectrometry. 276: 153-159. DOI: 10.1016/J.Ijms.2008.05.038 |
0.33 |
|
2007 |
Schenauer MR, Yu Y, Sweeney MD, Leary JA. CCR2 chemokines bind selectively to acetylated heparan sulfate octasaccharides. The Journal of Biological Chemistry. 282: 25182-8. PMID 17597064 DOI: 10.1074/Jbc.M703387200 |
0.79 |
|
2007 |
Kumar P, Schelle MW, Jain M, Lin FL, Petzold CJ, Leavell MD, Leary JA, Cox JS, Bertozzi CR. PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proceedings of the National Academy of Sciences of the United States of America. 104: 11221-6. PMID 17592143 DOI: 10.1073/Pnas.0611649104 |
0.488 |
|
2007 |
Yu Y, Hoffhines AJ, Moore KL, Leary JA. Determination of the sites of tyrosine O-sulfation in peptides and proteins. Nature Methods. 4: 583-8. PMID 17558413 DOI: 10.1038/Nmeth1056 |
0.522 |
|
2007 |
Jain M, Petzold CJ, Schelle MW, Leavell MD, Mougous JD, Bertozzi CR, Leary JA, Cox JS. Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proceedings of the National Academy of Sciences of the United States of America. 104: 5133-8. PMID 17360366 DOI: 10.1073/Pnas.0610634104 |
0.475 |
|
2007 |
Damoc E, Fraser CS, Zhou M, Videler H, Mayeur GL, Hershey JW, Doudna JA, Robinson CV, Leary JA. Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. Molecular & Cellular Proteomics : McP. 6: 1135-46. PMID 17322308 DOI: 10.1074/Mcp.M600399-Mcp200 |
0.409 |
|
2007 |
Gao H, Leary J, Carroll KS, Bertozzi CR, Chen H. Noncovalent complexes of APS reductase from M. tuberculosis: delineating a mechanistic model using ESI-FTICR MS. Journal of the American Society For Mass Spectrometry. 18: 167-78. PMID 17023175 DOI: 10.1016/J.Jasms.2006.08.010 |
0.448 |
|
2007 |
Yu Y, Hoffhines AJ, Moore KL, Leary JA. A novel method for site-determination of tyrosine O-sulfation in peptides and proteins Nature Protocols. DOI: 10.1038/Nprot.2007.388 |
0.447 |
|
2006 |
Hoffhines AJ, Damoc E, Bridges KG, Leary JA, Moore KL. Detection and purification of tyrosine-sulfated proteins using a novel anti-sulfotyrosine monoclonal antibody. The Journal of Biological Chemistry. 281: 37877-87. PMID 17046811 DOI: 10.1074/Jbc.M609398200 |
0.32 |
|
2006 |
Chartron J, Carroll KS, Shiau C, Gao H, Leary JA, Bertozzi CR, Stout CD. Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. Journal of Molecular Biology. 364: 152-69. PMID 17010373 DOI: 10.1016/J.Jmb.2006.08.080 |
0.508 |
|
2006 |
Leary JA. How complex is a complex? Nature Chemical Biology. 2: 515-6. PMID 16983385 DOI: 10.1038/Nchembio1006-515 |
0.352 |
|
2006 |
Leavell MD, Leary JA. Fatty acid analysis tool (FAAT): An FT-ICR MS lipid analysis algorithm. Analytical Chemistry. 78: 5497-503. PMID 16878888 DOI: 10.1021/Ac0604179 |
0.366 |
|
2006 |
Otto VI, Damoc E, Cueni LN, Schürpf T, Frei R, Ali S, Callewaert N, Moise A, Leary JA, Folkers G, Przybylski M. N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry. Glycobiology. 16: 1033-44. PMID 16877748 DOI: 10.1093/Glycob/Cwl032 |
0.345 |
|
2006 |
Crown SE, Yu Y, Sweeney MD, Leary JA, Handel TM. Heterodimerization of CCR2 chemokines and regulation by glycosaminoglycan binding. The Journal of Biological Chemistry. 281: 25438-46. PMID 16803905 DOI: 10.1074/Jbc.M601518200 |
0.535 |
|
2006 |
Sweeney MD, Yu Y, Leary JA. Effects of sulfate position on heparin octasaccharide binding to CCL2 examined by tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 1114-9. PMID 16735126 DOI: 10.1016/J.Jasms.2006.04.025 |
0.532 |
|
2006 |
Mougous JD, Senaratne RH, Petzold CJ, Jain M, Lee DH, Schelle MW, Leavell MD, Cox JS, Leary JA, Riley LW, Bertozzi CR. A sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 4258-63. PMID 16537518 DOI: 10.1073/Pnas.0510861103 |
0.493 |
|
2006 |
Yu Y, Sweeney MD, Saad OM, Leary JA. Potential inhibitors of chemokine function: analysis of noncovalent complexes of CC chemokine and small polyanionic molecules by ESI FT-ICR mass spectrometry. Journal of the American Society For Mass Spectrometry. 17: 524-35. PMID 16503157 DOI: 10.1016/J.Jasms.2005.12.008 |
0.546 |
|
2006 |
Yu Y, Sweeney MD, Saad OM, Crown SE, Handel TM, Leary JA. Potential Inhibitors of Chemokine Function: Analysis of Noncovalent Complexes of CC Chemokine and Small Polyanionic Molecules by ESI FT-ICR Mass Spectrometry (DOI:10.1016/j.jasms.2005.12.008) Journal of the American Society For Mass Spectrometry. 17: 1040. DOI: 10.1016/J.Jasms.2006.04.027 |
0.52 |
|
2005 |
Carroll KS, Gao H, Chen H, Leary JA, Bertozzi CR. Investigation of the iron-sulfur cluster in Mycobacterium tuberculosis APS reductase: implications for substrate binding and catalysis. Biochemistry. 44: 14647-57. PMID 16262264 DOI: 10.1021/Bi051344A |
0.464 |
|
2005 |
Saad OM, Leary JA. Heparin sequencing using enzymatic digestion and ESI-MSn with HOST: a heparin/HS oligosaccharide sequencing tool. Analytical Chemistry. 77: 5902-11. PMID 16159120 DOI: 10.1021/Ac050793D |
0.368 |
|
2005 |
Gao H, Yu Y, Leary JA. Mechanism and kinetics of metalloenzyme phosphomannose isomerase: measurement of dissociation constants and effect of zinc binding using ESI-FTICR mass spectrometry. Analytical Chemistry. 77: 5596-603. PMID 16131071 DOI: 10.1021/Ac050549M |
0.577 |
|
2005 |
Saad OM, Myers RA, Castleton DL, Leary JA. Analysis of hyaluronan content in chondroitin sulfate preparations by using selective enzymatic digestion and electrospray ionization mass spectrometry. Analytical Biochemistry. 344: 232-9. PMID 16081034 DOI: 10.1016/J.Ab.2005.06.041 |
0.352 |
|
2005 |
Yu Y, Sweeney MD, Saad OM, Crown SE, Hsu AR, Handel TM, Leary JA. Chemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry. The Journal of Biological Chemistry. 280: 32200-8. PMID 16033763 DOI: 10.1074/Jbc.M505738200 |
0.532 |
|
2005 |
Carroll KS, Gao H, Chen H, Stout CD, Leary JA, Bertozzi CR. A conserved mechanism for sulfonucleotide reduction. Plos Biology. 3: e250. PMID 16008502 DOI: 10.1371/Journal.Pbio.0030250 |
0.491 |
|
2005 |
Petzold CJ, Stanton LH, Leary JA. Structural characterization of Lipoarabinomannans from Mycobacterium tuberculosis and Mycobacterium smegmatis by ESI mass spectrometry. Journal of the American Society For Mass Spectrometry. 16: 1109-16. PMID 15923126 DOI: 10.1016/J.Jasms.2005.02.023 |
0.419 |
|
2005 |
Yu Y, Ji H, Doudna JA, Leary JA. Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. Protein Science : a Publication of the Protein Society. 14: 1438-46. PMID 15883184 DOI: 10.1110/Ps.041293005 |
0.522 |
|
2005 |
Pi N, Hoang MB, Gao H, Mougous JD, Bertozzi CR, Leary JA. Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry. Analytical Biochemistry. 341: 94-104. PMID 15866533 DOI: 10.1016/J.Ab.2005.02.004 |
0.568 |
|
2005 |
Saad OM, Ebel H, Uchimura K, Rosen SD, Bertozzi CR, Leary JA. Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology. 15: 818-26. PMID 15843596 DOI: 10.1093/Glycob/Cwi064 |
0.511 |
|
2005 |
Gao H, Chen Y, Leary JA. Kinetic measurements of phosphoglucose isomerase and phosphomannose isomerase by direct analysis of phosphorylated aldose-ketose isomers using tandem mass spectrometry International Journal of Mass Spectrometry. 240: 291-299. DOI: 10.1016/J.Ijms.2004.09.017 |
0.396 |
|
2004 |
Ji H, Fraser CS, Yu Y, Leary J, Doudna JA. Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 16990-5. PMID 15563596 DOI: 10.1073/Pnas.0407402101 |
0.467 |
|
2004 |
Yu Y, Kirkup CE, Pi N, Leary JA. Characterization of noncovalent protein-ligand complexes and associated enzyme intermediates of GlcNAc-6-O-sulfotransferase by electrospray ionization FT-ICR mass spectrometry. Journal of the American Society For Mass Spectrometry. 15: 1400-7. PMID 15465352 DOI: 10.1016/J.Jasms.2004.06.002 |
0.566 |
|
2004 |
Saad OM, Leary JA. Delineating mechanisms of dissociation for isomeric heparin disaccharides using isotope labeling and ion trap tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 15: 1274-86. PMID 15337508 DOI: 10.1016/J.Jasms.2004.05.008 |
0.43 |
|
2004 |
Mougous JD, Petzold CJ, Senaratne RH, Lee DH, Akey DL, Lin FL, Munchel SE, Pratt MR, Riley LW, Leary JA, Berger JM, Bertozzi CR. Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nature Structural & Molecular Biology. 11: 721-9. PMID 15258569 DOI: 10.1038/Nsmb802 |
0.514 |
|
2004 |
Pi N, Meyers CL, Pacholec M, Walsh CT, Leary JA. Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton. Proceedings of the National Academy of Sciences of the United States of America. 101: 10036-41. PMID 15218104 DOI: 10.1073/Pnas.0403526101 |
0.362 |
|
2004 |
Gao H, Leary JA. Kinetic measurements of phosphoglucomutase by direct analysis of glucose-1-phosphate and glucose-6-phosphate using ion/molecule reactions and Fourier transform ion cyclotron resonance mass spectrometry. Analytical Biochemistry. 329: 269-75. PMID 15158486 DOI: 10.1016/J.Ab.2004.03.011 |
0.342 |
|
2004 |
Pi N, Yu Y, Mougous JD, Leary JA. Observation of a hybrid random ping-pong mechanism of catalysis for NodST: a mass spectrometry approach. Protein Science : a Publication of the Protein Society. 13: 903-12. PMID 15044725 DOI: 10.1110/Ps.03581904 |
0.571 |
|
2004 |
Pi N, Leary JA. Determination of enzyme/substrate specificity constants using a multiple substrate ESI-MS assay. Journal of the American Society For Mass Spectrometry. 15: 233-43. PMID 14766290 DOI: 10.1016/J.Jasms.2003.10.009 |
0.371 |
|
2004 |
Petzold CJ, Leavell MD, Leary JA. Screening and identification of acidic carbohydrates in bovine colostrum by using ion/molecule reactions and Fourier transform ion cyclotron resonance mass spectrometry: specificity toward phosphorylated complexes. Analytical Chemistry. 76: 203-10. PMID 14697052 DOI: 10.1021/Ac034682V |
0.378 |
|
2003 |
Saad OM, Leary JA. Compositional analysis and quantification of heparin and heparan sulfate by electrospray ionization ion trap mass spectrometry. Analytical Chemistry. 75: 2985-95. PMID 12964742 DOI: 10.1021/Ac0340455 |
0.42 |
|
2003 |
Gao H, Petzold CJ, Leavell MD, Leary JA. Investigation of ion/molecule reactions as a quantification method for phosphorylated positional isomers. an FT-ICR approach. Journal of the American Society For Mass Spectrometry. 14: 916-24. PMID 12892915 DOI: 10.1016/S1044-0305(03)00401-X |
0.37 |
|
2003 |
Converse SE, Mougous JD, Leavell MD, Leary JA, Bertozzi CR, Cox JS. MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proceedings of the National Academy of Sciences of the United States of America. 100: 6121-6. PMID 12724526 DOI: 10.1073/Pnas.1030024100 |
0.492 |
|
2003 |
Leavell MD, Leary JA. Probing isomeric differences of phosphorylated carbohydrates through the use of ion/molecule reactions and FT-ICR MS. Journal of the American Society For Mass Spectrometry. 14: 323-31. PMID 12686479 DOI: 10.1016/S1044-0305(03)00067-9 |
0.4 |
|
2003 |
Gao H, Leary JA. Multiplex inhibitor screening and kinetic constant determinations for yeast hexokinase using mass spectrometry based assays. Journal of the American Society For Mass Spectrometry. 14: 173-81. PMID 12648923 DOI: 10.1016/S1044-0305(02)00867-X |
0.395 |
|
2003 |
Leavell MD, Kruppa GH, Leary JA. Determination of phosphate position in hexose monosaccharides using an FTICR mass spectrometer: Ion/molecule reactions, labeling studies, and dissociation mechanisms International Journal of Mass Spectrometry. 222: 135-153. DOI: 10.1016/S1387-3806(02)00986-7 |
0.414 |
|
2002 |
Mougous JD, Leavell MD, Senaratne RH, Leigh CD, Williams SJ, Riley LW, Leary JA, Bertozzi CR. Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proceedings of the National Academy of Sciences of the United States of America. 99: 17037-42. PMID 12482950 DOI: 10.1073/Pnas.252514899 |
0.51 |
|
2002 |
Pi N, Armstrong JI, Bertozzi CR, Leary JA. Kinetic analysis of NodST sulfotransferase using an electrospray ionization mass spectrometry assay. Biochemistry. 41: 13283-8. PMID 12403630 DOI: 10.1021/Bi020457G |
0.54 |
|
2002 |
Leavell MD, Kruppa GH, Leary JA. Analysis of phosphate position in hexose monosaccharides using ion-molecule reactions and SORI-CID on an FT-ICR mass spectrometer. Analytical Chemistry. 74: 2608-11. PMID 12069245 DOI: 10.1021/Ac020054M |
0.383 |
|
2002 |
Desaire H, Leavell MD, Leary JA. Solvent effects in tandem mass spectrometry: mechanistic studies indicating how a change in solvent conditions and pH can dramatically alter CID spectra. The Journal of Organic Chemistry. 67: 3693-9. PMID 12027682 DOI: 10.1021/Jo016309Y |
0.637 |
|
2002 |
Leavell MD, Leary JA, Yamasaki R. Mass spectrometric strategy for the characterization of lipooligosaccharides from Neisseria gonorrhoeae 302 using FTICR. Journal of the American Society For Mass Spectrometry. 13: 571-6. PMID 12019980 DOI: 10.1016/S1044-0305(02)00360-4 |
0.406 |
|
2002 |
Leavell MD, Gaucher SP, Leary JA, Taraszka JA, Clemmer DE. Conformational studies of Zn-ligand-hexose diastereomers using ion mobility measurements and density functional theory calculations. Journal of the American Society For Mass Spectrometry. 13: 284-93. PMID 11908808 DOI: 10.1016/S1044-0305(01)00362-2 |
0.666 |
|
2001 |
Ge X, Sirich TL, Beyer MK, Desaire H, Leary JA. A strategy for the determination of enzyme kinetics using electrospray ionization with an ion trap mass spectrometer. Analytical Chemistry. 73: 5078-82. PMID 11721902 DOI: 10.1021/Ac0105890 |
0.729 |
|
2001 |
Schilling B, Goon S, Samuels NM, Gaucher SP, Leary JA, Bertozzi CR, Gibson BW. Biosynthesis of sialylated lipooligosaccharides in Haemophilus ducreyi is dependent on exogenous sialic acid and not mannosamine. Incorporation studies using N-acylmannosamine analogues, N-glycolylneuraminic acid, and 13C-labeled N-acetylneuraminic acid. Biochemistry. 40: 12666-77. PMID 11601991 DOI: 10.1021/Bi0107849 |
0.702 |
|
2001 |
Desaire H, Sirich TL, Leary JA. Evidence of block and randomly sequenced chondroitin polysaccharides: sequential enzymatic digestion and quantification using ion trap tandem mass spectrometry. Analytical Chemistry. 73: 3513-20. PMID 11510812 DOI: 10.1021/Ac010385J |
0.624 |
|
2001 |
Armstrong JI, Ge X, Verdugo DE, Winans KA, Leary JA, Bertozzi CR. A library approach to the generation of bisubstrate analogue sulfotransferase inhibitors. Organic Letters. 3: 2657-60. PMID 11506602 DOI: 10.1021/Ol0162217 |
0.348 |
|
2001 |
Verdugo DE, Cancilla MT, Ge X, Gray NS, Chang YT, Schultz PG, Negishi M, Leary JA, Bertozzi CR. Discovery of estrogen sulfotransferase inhibitors from a purine library screen. Journal of Medicinal Chemistry. 44: 2683-6. PMID 11495578 DOI: 10.1021/Jm010171U |
0.394 |
|
2001 |
Leavell MD, Leary JA. Stabilization and linkage analysis of metal-ligated sialic acid containing oligosaccharides Journal of the American Society For Mass Spectrometry. 12: 528-536. PMID 11349950 DOI: 10.1016/S1044-0305(01)00238-0 |
0.331 |
|
2001 |
Desaire H, Beyer MK, Leary JA. Molecular orbital considerations in probing the stereoselective dissociations of cobalt-coordinated hexosamine monosaccharides. Journal of the American Society For Mass Spectrometry. 12: 517-27. PMID 11349949 DOI: 10.1016/S1044-0305(01)00233-1 |
0.737 |
|
2001 |
Desaire H, Leary JA. The effects of coordination number and ligand size on the gas phase dissociation and stereochemical differentiation of cobalt-coordinated monosaccharides International Journal of Mass Spectrometry. 209: 171-184. DOI: 10.1016/S1387-3806(01)00498-5 |
0.614 |
|
2001 |
Leavell MD, Leary JA. Dissociation mechanisms for metal N-glycosides of N-acetyl neuraminic acid International Journal of Mass Spectrometry. 204: 185-196. DOI: 10.1016/S1387-3806(00)00365-1 |
0.32 |
|
2000 |
Desaire H, Leary JA. Utilization of MS3 spectra for the multicomponent quantification of diastereomeric N-acetylhexosamines. Journal of the American Society For Mass Spectrometry. 11: 1086-94. PMID 11118116 DOI: 10.1016/S1044-0305(00)00179-3 |
0.661 |
|
2000 |
Cancilla MT, Leavell MD, Chow J, Leary JA. Mass spectrometry and immobilized enzymes for the screening of inhibitor libraries Proceedings of the National Academy of Sciences of the United States of America. 97: 12008-12013. PMID 11035807 DOI: 10.1073/Pnas.220403997 |
0.366 |
|
2000 |
Gaucher SP, Cancilla MT, Phillips NJ, Gibson BW, Leary JA. Mass spectral characterization of lipooligosaccharides from Haemophilus influenzae 2019. Biochemistry. 39: 12406-14. PMID 11015221 DOI: 10.1021/Bi001181K |
0.69 |
|
2000 |
Desaire H, Leary JA. Detection and quantification of the sulfated disaccharides in chondroitin sulfate by electrospray tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 11: 916-20. PMID 11014453 DOI: 10.1016/S1044-0305(00)00168-9 |
0.651 |
|
2000 |
Cancilla MT, Gaucher SP, Desaire H, Leary JA. Combined partial acid hydrolysis and electrospray ionization-mass spectrometry for the structural determination of oligosaccharides. Analytical Chemistry. 72: 2901-7. PMID 10905325 DOI: 10.1021/Ac991223E |
0.775 |
|
2000 |
Gaucher SP, Morrow J, Leary JA. STAT: a saccharide topology analysis tool used in combination with tandem mass spectrometry. Analytical Chemistry. 72: 2331-6. PMID 10857602 DOI: 10.1021/Ac000096F |
0.678 |
|
2000 |
Beyer MK, Leary JA. Comment on “Energy-Resolved Collision-Induced Dissociation of Fe2(CO)y+(y= 1−9)” The Journal of Physical Chemistry A. 104: 9395-9396. DOI: 10.1021/Jp001067B |
0.473 |
|
2000 |
Gaucher SP, Leary JA. Influence of metal ion and coordination geometry on the gas phase dissociation and stereochemical differentiation of N-glycosides International Journal of Mass Spectrometry. 197: 139-148. DOI: 10.1016/S1387-3806(99)00238-9 |
0.675 |
|
1999 |
Desaire H, Leary JA. Multicomponent quantification of diastereomeric hexosamine monosaccharides using ion trap tandem mass spectrometry. Analytical Chemistry. 71: 4142-7. PMID 10517139 DOI: 10.1021/Ac990553W |
0.659 |
|
1999 |
Desaire H, Leary JA. Differentiation of diastereomeric N-acetylhexosamine monosaccharides using ion trap tandem mass spectrometry. Analytical Chemistry. 71: 1997-2002. PMID 10361499 DOI: 10.1021/Ac981052Y |
0.644 |
|
1999 |
Gaucher SP, Leary JA. Determining anomericity of the glycosidic bond in Zn(II)-diethylenetriamine-disaccharide complexes using MSn in a quadrupole ion trap. Journal of the American Society For Mass Spectrometry. 10: 269-72. PMID 10069047 DOI: 10.1016/S1044-0305(98)00149-4 |
0.688 |
|
1999 |
Gaucher SP, Pedersen SF, Leary JA. Stereospecific synthesis and characterization of aminoglycoside ligands from diethylenetriamine Journal of Organic Chemistry. 64: 4012-4015. DOI: 10.1021/Jo9900331 |
0.653 |
|
1999 |
Smith G, Leary JA. Synthesis and analysis of electrospray ionization-generated five-coordinate diastereomeric Ni-N-glycoside complexes using a quadrupole ion trap mass spectrometer International Journal of Mass Spectrometry. 193: 153-160. DOI: 10.1016/S1387-3806(99)00112-8 |
0.367 |
|
1999 |
Smith G, Kaffashan A, Leary JA. Influence Of Coordination Number And Ligand Size On The Dissociation Mechanisms Of Transition Metal-Monosaccharide Complexes International Journal of Mass Spectrometry. 182: 299-310. DOI: 10.1016/S1387-3806(98)14244-6 |
0.351 |
|
1999 |
Andersen UN, König S, Leary JA, Freitas MA, Marshall AG. Characterization of a single crystal cubic Prussian blue Co8(tacn)8(CN)12 cluster by ion trap and Fourier transform ion cyclotron resonance mass spectrometry with microelectrospray ionization Journal of the American Society For Mass Spectrometry. 10: 352-354. DOI: 10.1016/S1044-0305(98)00154-8 |
0.375 |
|
1998 |
Gaucher SP, Leary JA. Stereochemical Differentiation of Mannose, Glucose, Galactose, and Talose Using Zinc(II) Diethylenetriamine and ESI-Ion Trap Mass Spectrometry. Analytical Chemistry. 70: 3337. PMID 21644669 DOI: 10.1021/Ac9815599 |
0.706 |
|
1998 |
König S, Leary JA. Evidence for linkage position determination in cobalt coordinated pentasaccharides using ion trap mass spectrometry. Journal of the American Society For Mass Spectrometry. 9: 1125-34. PMID 9794083 DOI: 10.1016/S1044-0305(98)00096-8 |
0.414 |
|
1998 |
Gaucher SP, Leary JA. Stereochemical differentiation of mannose, glucose, galactose, and talose using zinc(II) diethylenetriamine and ESI-ion trap mass spectrometry. Analytical Chemistry. 70: 3009-14. PMID 9684549 |
0.682 |
|
1998 |
Smith G, Leary JA. Mechanistic studies of diastereomeric nickel(II) N-glycoside complexes using tandem mass spectrometry Journal of the American Chemical Society. 120: 13046-13056. DOI: 10.1021/Ja9814319 |
0.408 |
|
1998 |
König S, Brückner C, Raymond KN, Leary JA. Electrospray ionization ion trap mass spectrometry of a tetrahedral supramolecular Ti4L4 cluster Journal of the American Society For Mass Spectrometry. 9: 1099-1103. DOI: 10.1016/S1044-0305(98)00095-6 |
0.377 |
|
1997 |
Sible EM, Brimmer SP, Leary JA. Interaction of first row transition metals with α1-3, α1-6 mannotriose and conserved trimannosyl core oligosaccharides: A comparative electrospray ionization study of doubly and singly charged complexes Journal of the American Society For Mass Spectrometry. 8: 32-42. DOI: 10.1016/S1044-0305(97)82229-5 |
0.399 |
|
1997 |
Kohler M, Leary JA. Gas phase reactions of doubly charged alkaline earth and transition metal(II)-ligand complexes generated by electrospray ionization International Journal of Mass Spectrometry and Ion Processes. 162: 17-34. DOI: 10.1016/S0168-1176(96)04474-6 |
0.306 |
|
1997 |
Zheng YJ, Ornstein RL, Leary JA. A density functional theory investigation of metal ion binding sites in monosaccharides Journal of Molecular Structure: Theochem. 389: 233-240. DOI: 10.1016/S0166-1280(96)04707-0 |
0.315 |
|
1996 |
Smith G, Leary JA. Differentiation of diastereomeric nickel(II) N-glycoside complexes using tandem mass spectrometry and kinetic energy release measurements Journal of the American Chemical Society. 118: 3293-3294. DOI: 10.1021/Ja952915X |
0.411 |
|
1996 |
Smith G, Leary JA. Differentiation of stereochemistry of glycosidic bond configuration: Tandem mass spectrometry of diastereomeric cobalt-glucosyl-glucose disaccharide complexes Journal of the American Society For Mass Spectrometry. 7: 953-957. DOI: 10.1016/1044-0305(96)80513-7 |
0.387 |
|
1995 |
Kohler M, Leary JA. LC/MS/MS of carbohydrates with postcolumn addition of metal chlorides using a triaxial electrospray probe Analytical Chemistry. 67: 3501-3508. PMID 8686898 DOI: 10.1021/Ac00115A019 |
0.373 |
|
1994 |
Dang TT, Pedersen SF, Leary JA. Chiral recognition in the gas phase: Mass spectrometric studies of diastereomeric cobalt complexes. Journal of the American Society For Mass Spectrometry. 5: 452-9. PMID 24222600 DOI: 10.1016/1044-0305(94)85061-5 |
0.383 |
|
1993 |
Fura A, Leary JA. Differentiation of Ca2+- and Mg2+-coordinated branched trisaccharide isomers: An electrospray ionization and tandem mass spectrometry study Analytical Chemistry. 65: 2805-2811. PMID 8250263 DOI: 10.1021/Ac00068A017 |
0.365 |
|
1993 |
Zheng YJ, Staempfli A, Leary JA. Mechanism of gas-phase aldose-ketose isomerization: A study using tandem mass spectrometry and theoretical calculations Journal of the American Society For Mass Spectrometry. 4: 943-948. DOI: 10.1016/1044-0305(93)80020-Y |
0.328 |
|
1992 |
Staempfli A, Zhou Z, Leary JA. Gas-phase dissociation mechanisms of dilithiated disaccharides: Tandem mass spectrometry and semiempirical calculations Journal of Organic Chemistry. 57: 3590-3594. DOI: 10.1021/Jo00039A016 |
0.368 |
|
1991 |
Hofmeister GE, Zhou Z, Leary JA. Linkage position determination in lithium-cationized disaccharides: Tandem mass spectrometry and semiempirical calculations Journal of the American Chemical Society. 113: 5964-5970. DOI: 10.1021/Ja00016A007 |
0.394 |
|
1991 |
Hofmeister G, Leary JA. Chiral recognition of lithium-coordinated diols using tandem mass spectrometry Organic Mass Spectrometry. 26: 811-812. DOI: 10.1002/Oms.1210260922 |
0.349 |
|
1990 |
Leary JA, Zhou Z, Ogden SA, Williams TD. Investigations of gas-phase lithium-peptide adducts: Tandem. mass spectrometry and semiempirical studies. Journal of the American Society For Mass Spectrometry. 1: 473-80. PMID 24248981 DOI: 10.1016/1044-0305(90)85030-P |
0.381 |
|
1990 |
Zhou Z, Ogden S, Leary JA. Linkage position determination in oligosaccharides: mass spectrometry (MS/MS) study of lithium-cationized carbohydrates The Journal of Organic Chemistry. 55: 5444-5446. DOI: 10.1021/Jo00307A011 |
0.362 |
|
1990 |
Hofmeister GE, Alvarado E, Leary JA, Yoon DI, Pedersen SF. Synthesis and characterization of dimetallacalix[8]arene complexes Journal of the American Chemical Society. 112: 8843-8851. DOI: 10.1021/Ja00180A028 |
0.402 |
|
1989 |
Leary JA, Williams TD, Bott G. Strategy for sequencing peptides as mono- and dilithiated adducts using a hybrid tandem mass spectrometer Rapid Communications in Mass Spectrometry. 3: 192-196. DOI: 10.1002/Rcm.1290030608 |
0.326 |
|
1987 |
Leary JA, Biemann K, Lafleur AL, Kruzel EL, Prado GP, Longwell JP, Peters WA. Chemical and toxicological characterization of residential oil burner emissions: I. Yields and chemical characterization of extractables from combustion of No. 2 fuel oil at different Bacharach Smoke Numbers and firing cycles. Environmental Health Perspectives. 73: 223-34. PMID 3665865 DOI: 10.1289/Ehp.8773223 |
0.397 |
|
1984 |
Leary JA, Biemann K, Braun A, Lafleur AL, Liber HL, Longwell JP, Peters WA. CHEMICAL AND TOXICOLOGIC CHARACTERIZATION OF NO. 2 FUEL OIL AND ITS COMBUSTION PRODUCTS AT DIFFERENT SMOKE NUMBERS National Meeting - American Chemical Society, Division of Environmental Chemistry. 24: 167-169. |
0.383 |
|
1983 |
Leary JA, Lafleur AL, Blemann K. Chemical and toxicologic characterization of fossil fuel combustion product phenalen-1-one Analytical Chemistry. 55: 758-761. PMID 6344693 DOI: 10.1021/Ac00255A038 |
0.342 |
|
1983 |
Leary JA, Lafleur AL, Longwell JP, Peters WA, Kruzel EL, Biemann K. CHEMICAL CHARACTERIZATION OF DOMESTIC FUEL OIL AND ITS COMBUSTION PRODUCTS Polynuclear Aromatic Hydrocarbons, International Symposium. 799-808. |
0.383 |
|
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