Lakshmi R. Palam, Ph.D. - Publications

Affiliations: 
2012 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry, Molecular Biology, Cell Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ramdas B, Mali RS, Palam LR, Pandey R, Cai Z, Pasupuleti SK, Burns SS, Kapur R. Driver Mutations in Leukemia Promote Disease Pathogenesis through a Combination of Cell-Autonomous and Niche Modulation. Stem Cell Reports. PMID 32502465 DOI: 10.1016/J.Stemcr.2020.05.002  0.311
2019 Garg G, Muschaweckh A, Moreno H, Vasanthakumar A, Floess S, Lepennetier G, Oellinger R, Zhan Y, Regen T, Hiltensperger M, Peter C, Aly L, Knier B, Palam LR, Kapur R, et al. Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation. Cell Reports. 26: 1854-1868.e5. PMID 30759395 DOI: 10.1016/J.Celrep.2019.01.070  0.37
2019 Ramdas B, Palam LR, Mali RS, Cai Z, Pandey R, Kapur R. Combined Heterozygous Loss of Tet2 and Dnmt3a Along with Expression of Flt3ITD/WT results in Acute Myeloid Leukemia Which Responds to a Combination of FLT3 Inhibitor, APE1 Inhibitor and Decitabine Blood. 134: 3754-3754. DOI: 10.1182/Blood-2019-131172  0.327
2019 Palam LR, Ramdas B, Pickerell K, Kapur R. Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid Skewing Due to Loss of Dnmt3a Blood. 134: 723-723. DOI: 10.1182/Blood-2019-131036  0.395
2019 Rangaraju S, Marino S, Roodman GD, Cripe LD, Ramdas B, Palam LR, Sargent KJ, Sayar H, Konig H, Kapur R, Boswell HS. Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations Blood. 134: 5051-5051. DOI: 10.1182/Blood-2019-124384  0.419
2018 Cai Z, Kotzin JJ, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali RS, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis. Cell Stem Cell. 23: 833-849.e5. PMID 30526882 DOI: 10.1016/J.Stem.2018.10.013  0.411
2018 Palam LR, Mali RS, Ramdas B, Srivatsan SN, Visconte V, Tiu RV, Vanhaesebroeck B, Roers A, Gerbaulet A, Xu M, Janga SC, Takemoto CM, Paczesny S, Kapur R. Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway. Jci Insight. 3. PMID 29467326 DOI: 10.1172/Jci.Insight.94679  0.427
2018 Palam LR, Ramdas B, Srivatsan Sr, Janga SC, Roers A, Gerbaulet A, Kapur R. Temporal and Spatially Regulated Oncogenic KIT Expression and Loss of Dnmt3a Cooperate to Drive MPN Development: Role of PI3Kinase in Dnmt3a Loss Induced Hyperproliferation in Myeloid Cells Blood. 132: 3055-3055. DOI: 10.1182/Blood-2018-99-118721  0.379
2018 Cai Z, Kotzin J, Ramdas B, Chen S, Nelanuthala S, Palam LR, Pandey R, Mali R, Liu Y, Kelley MR, Sandusky G, Mohseni M, Williams A, Henao-Mejia J, Kapur R. Downregulation of Morrbid in Tet2-Deficient Preleukemic Cells Overcomes Resistance to Inflammatory Stress and Mitigates Clonal Hematopoiesis Blood. 132: 1288-1288. DOI: 10.1182/Blood-2018-99-116703  0.388
2018 Rangaraju S, Marino S, Petrusca DN, Cripe LD, Sargent KJ, Roodman GD, Sayar H, Ramdas B, Palam LR, Shanmugam R, Rogozea A, Konig H, Kapur R, Boswell HS. Identification of Beta-Catenin As a Novel Ubiquitin-Regulated Target of Combined Flβ3/Syk- and Proteasome Inhibitors for Interruption of LSC Signaling in Poor-Risk AML Blood. 132: 3949-3949. DOI: 10.1182/Blood-2018-99-111181  0.387
2016 Young SK, Palam LR, Wu C, Sachs MS, Wek RC. Ribosome Elongation Stall Directs Gene-Specific Translation In the Integrated Stress Response. The Journal of Biological Chemistry. PMID 26817837 DOI: 10.1074/Jbc.M115.705640  0.737
2015 Palam LR, Gore J, Craven KE, Wilson JL, Korc M. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma. Cell Death & Disease. 6: e1913. PMID 26469962 DOI: 10.1038/Cddis.2015.264  0.547
2015 Mali R, Martin HR, Ramdas B, Palam L, Visconte V, Ramon T, Hanenberg H, Xu M, Kapur R. Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells Blood. 126: 775-775. DOI: 10.1182/Blood.V126.23.775.775  0.363
2014 Baird TD, Palam LR, Fusakio ME, Willy JA, Davis CM, McClintick JN, Anthony TG, Wek RC. Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα. Molecular Biology of the Cell. 25: 1686-97. PMID 24648495 DOI: 10.1091/Mbc.E14-02-0704  0.724
2012 Dai MS, Challagundla KB, Sun XX, Palam LR, Zeng SX, Wek RC, Lu H. Physical and functional interaction between ribosomal protein L11 and the tumor suppressor ARF. The Journal of Biological Chemistry. 287: 17120-9. PMID 22467867 DOI: 10.1074/Jbc.M111.311902  0.589
2011 Palam LR, Baird TD, Wek RC. Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation. The Journal of Biological Chemistry. 286: 10939-49. PMID 21285359 DOI: 10.1074/Jbc.M110.216093  0.732
2010 Dey S, Baird TD, Zhou D, Palam LR, Spandau DF, Wek RC. Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response. The Journal of Biological Chemistry. 285: 33165-74. PMID 20732869 DOI: 10.1074/Jbc.M110.167213  0.73
2010 Staschke KA, Dey S, Zaborske JM, Palam LR, McClintick JN, Pan T, Edenberg HJ, Wek RC. Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast. The Journal of Biological Chemistry. 285: 16893-911. PMID 20233714 DOI: 10.1074/Jbc.M110.121947  0.651
2009 Butler JS, Palam LR, Tate CM, Sanford JR, Wek RC, Skalnik DG. DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells. Dna and Cell Biology. 28: 223-31. PMID 19388845 DOI: 10.1089/Dna.2009.0854  0.588
2008 Zhou D, Palam LR, Jiang L, Narasimhan J, Staschke KA, Wek RC. Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions. The Journal of Biological Chemistry. 283: 7064-73. PMID 18195013 DOI: 10.1074/Jbc.M708530200  0.728
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