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Richard N. Bergman - Publications

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
Endocrinology/Metabolism, Diabetes
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424 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pan S, A C Souza L, Worker CJ, Reyes Mendez ME, Gayban AJB, Cooper SG, Sanchez Solano A, Bergman RN, Stefanovski D, Morton GJ, Schwartz MW, Feng Earley Y. (Pro)renin receptor signaling in hypothalamic tyrosine hydroxylase neurons is required for obesity-associated glucose metabolic impairment. Jci Insight. PMID 38349753 DOI: 10.1172/jci.insight.174294  0.552
2024 Bergman RN. Pancreatic β cell function versus insulin resistance: application of the hyperbolic law of glucose tolerance. The Journal of Clinical Investigation. 134. PMID 38299589 DOI: 10.1172/JCI176738  0.466
2023 Hsu FC, Palmer ND, Chen SH, Ng MCY, Goodarzi MO, Rotter JI, Wagenknecht LE, Bancks MP, Bergman RN, Bowden DW. Methods for estimating insulin resistance from untargeted metabolomics data. Metabolomics : Official Journal of the Metabolomic Society. 19: 72. PMID 37558891 DOI: 10.1007/s11306-023-02035-5  0.468
2023 Williamson A, Norris DM, Yin X, Broadaway KA, Moxley AH, Vadlamudi S, Wilson EP, Jackson AU, Ahuja V, Andersen MK, Arzumanyan Z, Bonnycastle LL, Bornstein SR, Bretschneider MP, Buchanan TA, ... ... Bergman RN, et al. Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake. Nature Genetics. PMID 37291194 DOI: 10.1038/s41588-023-01408-9  0.544
2023 Kabir M, Bergman RN, Porter J, Stefanovski D, Paszkiewicz RL, Piccinini F, Woolcott OO, Yang H, Gopaul VS, Stiles L, Kolka CM. Dapagliflozin prevents abdominal visceral and subcutaneous adipose tissue dysfunction in the insulin-resistant canine model. Obesity (Silver Spring, Md.). PMID 37221655 DOI: 10.1002/oby.23771  0.69
2022 Bergman RN, Kabir M, Ader M. The Physiology of Insulin Clearance. International Journal of Molecular Sciences. 23. PMID 35163746 DOI: 10.3390/ijms23031826  0.49
2021 Ader M, Bergman RN. Hyperinsulinemic Compensation for Insulin Resistance Occurs Independent of Elevated Glycemia in Male Dogs. Endocrinology. 162. PMID 34132779 DOI: 10.1210/endocr/bqab119  0.61
2021 Bergman RN, Piccinini F. Response to Comment on Piccinini and Bergman The Measurement of Insulin Clearance. Diabetes Care 2020;43:2296-2302. Diabetes Care. 44: e100-e101. PMID 33972319 DOI: 10.2337/dci20-0080  0.346
2021 Paszkiewicz RL, Bergman RN, Santos RS, Frank AP, Woolcott OO, Iyer MS, Stefanovski D, Clegg DJ, Kabir M. Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. 2020, , 6639. International Journal of Molecular Sciences. 22. PMID 33922401 DOI: 10.3390/ijms22094366  0.423
2021 Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, et al. Voices: Insulin and beyond. Cell Metabolism. 33: 692-699. PMID 33826910 DOI: 10.1016/j.cmet.2021.03.017  0.481
2021 Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, ... ... Bergman RN, et al. Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications. 12: 995. PMID 33558525 DOI: 10.1038/s41467-021-21276-3  0.466
2021 Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, ... ... Bergman RN, et al. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications. 12: 24. PMID 33402679 DOI: 10.1038/s41467-020-19366-9  0.418
2020 Bergman RN. Origins and History of the Minimal Model of Glucose Regulation. Frontiers in Endocrinology. 11: 583016. PMID 33658981 DOI: 10.3389/fendo.2020.583016  0.322
2020 Paszkiewicz RL, Bergman RN, Santos RS, Frank AP, Woolcott OO, Iyer MS, Stefanovski D, Clegg DJ, Kabir M. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided. International Journal of Molecular Sciences. 21. PMID 32927872 DOI: 10.3390/Ijms21186639  0.592
2020 Piccinini F, Bergman RN. The Measurement of Insulin Clearance. Diabetes Care. 43: 2296-2302. PMID 32910777 DOI: 10.2337/dc20-0750  0.598
2020 Brouwer A, Asare Bediako I, Paszkiewicz RL, Kolka CM, Bergman RN, Broussard JL. Impact of sleep deprivation and high-fat feeding on insulin sensitivity and beta cell function in dogs. Diabetologia. PMID 32016566 DOI: 10.1007/s00125-019-05084-5  0.401
2020 O'Mara AE, Johnson JW, Linderman JD, Brychta RJ, McGehee S, Fletcher LA, Fink YA, Kapuria D, Cassimatis TM, Kelsey N, Cero C, Abdul-Sater Z, Piccinini F, Baskin AS, Leitner BP, ... ... Bergman RN, et al. Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity. The Journal of Clinical Investigation. PMID 31961826 DOI: 10.1172/Jci131126  0.487
2020 Woolcott OO, Bergman RN. Defining cutoffs to diagnose obesity using the relative fat mass (RFM): Association with mortality in NHANES 1999-2014. International Journal of Obesity (2005). PMID 31911664 DOI: 10.1038/s41366-019-0516-8  0.332
2020 Ader M, Kolka CM, Bergman RN. 1951-P: Glucose Effectiveness Fails to Compensate for Insulin Resistance after Fat Feeding in Dogs Diabetes. 69. DOI: 10.2337/Db20-1951-P  0.643
2020 Kabir M, Bergman RN, Piccinini F, Stefanovski D, Gopaul VS, Yang H, Kolka CM. 1711-P: Dapagliflozin Promotes Adipose Beiging and Lipolysis and Reduces Adipocyte Size in the Obese Prediabetic Dog Diabetes. 69. DOI: 10.2337/Db20-1711-P  0.731
2020 Ader M, Kolka CM, Bergman RN. Glucose Effectiveness Fails to Compensate for Insulin Resistance after Fat Feeding in Dogs Metabolism-Clinical and Experimental. 104: 154128. DOI: 10.1016/J.Metabol.2019.12.074  0.649
2019 Bergman RN, Piccinini F, Kabir M, Kolka CM, Ader M. Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes 2019;68:1709-1716. Diabetes. PMID 31597638 DOI: 10.2337/db19-er12a  0.464
2019 Bergman RN, Piccinini F, Kabir M, Kolka CM, Ader M. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes. 68: 1709-1716. PMID 31431441 DOI: 10.2337/db19-0098  0.562
2019 Iyer MS, Paszkiewicz RL, Bergman RN, Richey JM, Woolcott OO, Asare Bediako I, Wu Q, Kim SP, Stefanovski D, Kolka CM, Clegg DJ, Kabir M. Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs. American Journal of Physiology. Endocrinology and Metabolism. PMID 31237449 DOI: 10.1152/Ajpendo.00539.2018  0.708
2019 Bergman RN, Piccinini F, Kabir M, Ader M. Novel aspects of the role of the liver in carbohydrate metabolism. Metabolism: Clinical and Experimental. PMID 31158368 DOI: 10.1016/j.metabol.2019.05.011  0.613
2019 Muta K, Matsen ME, Acharya NK, Stefanovski D, Bergman RN, Schwartz MW, Morton GJ. Glucoregulatory responses to hypothalamic preoptic area cooling. Brain Research. PMID 30610874 DOI: 10.1016/J.Brainres.2019.01.002  0.734
2019 PICCININI F, GOWER B, FERNANDEZ JR, BERGMAN RN. 1843-P: Reduced Sampling for the Estimation of Hepatic and Extrahepatic Insulin Clearance in Children of Different Ethnicities Diabetes. 68: 1843-P. DOI: 10.2337/Db19-1843-P  0.444
2019 PASZKIEWICZ RK, BERGMAN RN, FRANK A, WOOLCOTT OO, SOUZA SANTOS RD, IYER MS, CLEGG D, KABIR M. 1761-P: Brain-Restricted CB1-Receptor Antagonists Increase Oxygen Consumption Rate and Promote Beiging in 3T3-L1 Adipocytes Similar to Rimonabant Suggesting that Central Effects Can Be Avoided Diabetes. 68: 1761-P. DOI: 10.2337/Db19-1761-P  0.333
2019 FABUNMI R, BERGMAN RN, PICCININI F, KIM T, ZHUANG D, TAYLOR K, KIM DD. 149-LB: The MetAP2 Inhibitor, ZGN-1061, Improves Insulin Sensitivity and Beta-Cell Function in Patients with Type 2 Diabetes Diabetes. 68: 149-LB. DOI: 10.2337/DB19-149-LB  0.331
2019 PICCININI F, GOWER B, FERNANDEZ JR, BERGMAN RN. 1330-P: Ethnic Differences in Insulin Clearance: Relationship with Admixture Scores, Diet, and Physical Activity Diabetes. 68: 1330-P. DOI: 10.2337/Db19-1330-P  0.497
2018 Scarlett JM, Muta K, Brown JM, Rojas JM, Matsen ME, Acharya NK, Secher A, Ingvorsen C, Jorgensen R, Høeg-Jensen T, Stefanovski D, Bergman RN, Piccinini F, Kaiyala KJ, Shiota M, et al. Peripheral Mechanisms Mediating the Sustained Anti-Diabetic Action of FGF1 in the Brain. Diabetes. PMID 30523024 DOI: 10.2337/Db18-0498  0.695
2018 Woolcott OO, Bergman RN. Relative fat mass (RFM) as a new estimator of whole-body fat percentage ─ A cross-sectional study in American adult individuals. Scientific Reports. 8: 10980. PMID 30030479 DOI: 10.1038/s41598-018-29362-1  0.321
2018 Piccinini F, Polidori DC, Gower BA, Fernandez JR, Bergman RN. Dissection of hepatic vs. extra-hepatic insulin clearance: ethnic differences in childhood. Diabetes, Obesity & Metabolism. PMID 30019375 DOI: 10.1111/Dom.13471  0.529
2018 Bergman RN, Piccinini F, Asare Bediako I, Kabir M, Kolka C, Polidori D, Ader M. Quantitative path to deep phenotyping: Possible importance of reduced hepatic insulin degradation to type 2 diabetes mellitus pathogenesis. Journal of Diabetes. PMID 29961982 DOI: 10.1111/1753-0407.12794  0.439
2018 Asare-Bediako I, Paszkiewicz RL, Kim SP, Woolcott OO, Kolka CM, Burch MA, Kabir M, Bergman RN. Variability of Directly Measured First-Pass Hepatic Insulin Extraction and its Association With Insulin Sensitivity and Plasma Insulin. Diabetes. PMID 29752425 DOI: 10.2337/Db17-1520  0.753
2018 Palmer ND, Okut H, Hsu FC, Ng MCY, Ida Chen YD, Goodarzi MO, Taylor KD, Norris JM, Lorenzo C, Rotter JI, Bergman RN, Langefeld CD, Wagenknecht LE, Bowden DW. Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS). The Journal of Clinical Endocrinology and Metabolism. PMID 29546329 DOI: 10.1210/Jc.2017-02203  0.513
2018 Asare-Bediako I, Paszkiewicz RL, Kim SP, Woolcott OO, Kolka CM, Burch M, Kabir M, Piccinini F, Bergman RN. Assessment of hepatic insulin extraction from in vivo surrogate methods of insulin clearance measurement. American Journal of Physiology. Endocrinology and Metabolism. PMID 29509434 DOI: 10.1152/Ajpendo.00344.2017  0.763
2018 PASZKIEWICZ RL, BERGMAN RN, RICHEY JM, IYER MS, WOOLCOTT OO, KOLKA CM, CLEGG D, KABIR M. Evidence of CB1-Receptor Antagonism in Fat-Fed Dogs Promoting Beiging of Adipose Tissue Mainly via Activation of Sarco/Endoplasmic Reticulum Ca2+ ATPase 2b and Ryanodine Receptor 2 Diabetes. 67: 2010-P. DOI: 10.2337/Db18-2010-P  0.305
2018 PICCININI F, POLIDORI D, GOWER B, FERNANDEZ JR, BERGMAN RN. Ethnic Differences in Hepatic Insulin Clearance Seen since Childhood Suggest a Genetic Basis Diabetes. 67: 1844-P. DOI: 10.2337/Db18-1844-P  0.502
2018 Bediako IA, Paszkiewicz RL, Woolcott OO, Bergman RN. Metabolic Clearance Rate of Insulin Is Not Saturable within the Physiological Range Diabetes. 67. DOI: 10.2337/Db18-1828-P  0.546
2018 PICCININI F, GOWER B, FERNANDEZ JR, BERGMAN RN. Metabolic Differences among Children of Different Ethnicities Are Magnified when Hepatic Insulin Extraction Is Included Diabetes. 67: 1336-P. DOI: 10.2337/Db18-1336-P  0.449
2018 PASZKIEWICZ RL, BERGMAN RN, BEDIAKO IA, MKRTCHYAN HJ, SASHI GOPAUL V, YANG H, LUNDBORG E, KIM S, FORMENTINI I, KOLKA CM. Dapagliflozin Improves Insulin Sensitivity in the Obese Prediabetic Canine Diabetes. 67: 113-LB. DOI: 10.2337/Db18-113-Lb  0.748
2017 Broussard JL, Bergman RN, Bediako IA, Paszkiewicz RL, Iyer MS, Kolka CM. Insulin Access to Skeletal Muscle is Preserved in Obesity Induced by Polyunsaturated Diet. Obesity (Silver Spring, Md.). PMID 29193779 DOI: 10.1002/oby.22057  0.608
2017 Schüler R, Osterhoff MA, Frahnow T, Möhlig M, Spranger J, Stefanovski D, Bergman RN, Xu L, Seltmann AC, Kabisch S, Hornemann S, Kruse M, Pfeiffer AFH. Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes. Scientific Reports. 7: 9234. PMID 28835639 DOI: 10.1038/S41598-017-08300-7  0.689
2017 Piccinini F, Polidori DC, Gower BA, Bergman RN. Hepatic but not Extra-hepatic Insulin Clearance is Lower in African American than in European American Women. Diabetes. PMID 28710139 DOI: 10.2337/Db17-0413  0.606
2017 Bergman RN, Iyer MS. Indirect Regulation of Endogenous Glucose Production by Insulin: The Single Gateway Hypothesis Revisited. Diabetes. 66: 1742-1747. PMID 28637826 DOI: 10.2337/db16-1320  0.627
2017 Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, ... ... Bergman RN, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/Db16-1253  0.379
2017 Wood AR, Jonsson A, Jackson AU, Wang N, van Leewen N, Palmer ND, Kobes S, Deelen J, Boquete-Vilarino L, Paananen J, Stančáková A, Boomsma DI, de Geus EJ, Eekhoff EM, Fritsche A, ... ... Bergman RN, et al. A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Diabetes. PMID 28490609 DOI: 10.2337/Db16-1452  0.553
2017 Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Bergman RN, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329  0.5
2017 Morton GJ, Muta K, Kaiyala KJ, Rojas JM, Scarlett JM, Matsen ME, Nelson JT, Acharya NK, Piccinini F, Stefanovski D, Bergman RN, Taborsky GJ, Kahn SE, Schwartz MW. Evidence that the Sympathetic Nervous System Elicits Rapid, Coordinated and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure. Diabetes. PMID 28115396 DOI: 10.2337/Db16-1351  0.745
2016 Nelson MD, Szczepaniak LS, Wei J, Szczepaniak E, Sánchez FJ, Vilain E, Stern JH, Bergman RN, Bairey Merz CN, Clegg DJ. Transwomen and the Metabolic Syndrome: Is Orchiectomy Protective? Transgender Health. 1: 165-171. PMID 29159307 DOI: 10.1089/trgh.2016.0016  0.348
2016 Broussard JL, Castro AV, Iyer M, Paszkiewicz RL, Bediako IA, Szczepaniak LS, Szczepaniak EW, Bergman RN, Kolka CM. Insulin access to skeletal muscle is impaired during the early stages of diet-induced obesity. Obesity (Silver Spring, Md.). 24: 1922-8. PMID 27569119 DOI: 10.1002/oby.21562  0.613
2016 Paszkiewicz RL, Bergman RN. Mechanisms of improved glucose handling after metabolic surgery: the big 6. Surgery For Obesity and Related Diseases : Official Journal of the American Society For Bariatric Surgery. 12: 1192-8. PMID 27568470 DOI: 10.1016/j.soard.2016.03.008  0.454
2016 Iyer MS, Bergman RN, Korman JE, Woolcott OO, Kabir M, Victor RG, Clegg DJ, Kolka C. Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet. Diabetes. PMID 27495220 DOI: 10.2337/Db16-0698  0.548
2016 Walford GA, Gustafsson S, Rybin D, Stančáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, ... ... Bergman RN, et al. Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci. Diabetes. PMID 27416945 DOI: 10.2337/Db16-0199  0.545
2016 Shankar SS, Vella A, Raymond RH, Staten MA, Calle RA, Bergman RN, Cao C, Chen D, Cobelli C, Dalla Man C, Deeg M, Dong JQ, Lee DS, Polidori D, Robertson RP, et al. Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series. Diabetes Care. PMID 27407117 DOI: 10.2337/Dc15-0931  0.619
2016 Ionut V, Woolcott OO, Mkrtchyan HJ, Stefanovski D, Kabir M, Iyer MS, Liu H, Castro AV, Wu Q, Broussard JL, Kolka CM, Asare-Bediako I, Bergman RN. Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes. Plos One. 11: e0158703. PMID 27398720 DOI: 10.1371/Journal.Pone.0158703  0.764
2016 Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW. Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents. Nature Medicine. PMID 27213816 DOI: 10.1038/Nm.4101  0.563
2016 Palmer ND, Wagenknecht LE, Langefeld CD, Wang N, Buchanan TA, Xiang AH, Allayee H, Bergman RN, Raffel LJ, Ida Chen YD, Haritunians T, Fingerlin T, Goodarzi MO, Taylor KD, Rotter JI, et al. Improved Performance of Dynamic Measures of Insulin Response over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. Diabetes. PMID 27207554 DOI: 10.2337/Db15-1543  0.529
2016 Polidori DC, Bergman RN, Chung ST, Sumner AE. Hepatic and Extra-Hepatic Insulin Clearance Are Differentially Regulated: Results from a Novel Model-Based Analysis of Intravenous Glucose Tolerance Data. Diabetes. PMID 26993071 DOI: 10.2337/db15-1373  0.629
2016 Woolcott OO, Gutierrez C, Castillo OA, Elashoff RM, Stefanovski D, Bergman RN. Inverse association between altitude and obesity: A prevalence study among andean and low-altitude adult individuals of Peru. Obesity (Silver Spring, Md.). PMID 26935008 DOI: 10.1002/Oby.21401  0.505
2016 Gower BA, Bergman R, Stefanovski D, Darnell B, Ovalle F, Fisher G, Sweatt SK, Resuehr HS, Pelkman C. Erratum to: Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial. Nutrition & Metabolism. 13: 6. PMID 26839576 DOI: 10.1186/S12986-016-0065-2  0.634
2016 Mathur R, Chua KS, Mamelak M, Morales W, Barlow GM, Thomas R, Stefanovski D, Weitsman S, Marsh Z, Bergman RN, Pimentel M. Metabolic effects of eradicating breath methane using antibiotics in prediabetic subjects with obesity. Obesity (Silver Spring, Md.). PMID 26833719 DOI: 10.1002/Oby.21385  0.513
2016 Gower BA, Bergman R, Stefanovski D, Darnell B, Ovalle F, Fisher G, Sweatt SK, Resuehr HS, Pelkman C. Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial. Nutrition & Metabolism. 13: 2. PMID 26766961 DOI: 10.1186/s12986-016-0062-5  0.646
2015 Broussard JL, Nelson MD, Kolka CM, Bediako IA, Paszkiewicz RL, Smith L, Szczepaniak EW, Stefanovski D, Szczepaniak LS, Bergman RN. Rapid development of cardiac dysfunction in a canine model of insulin resistance and moderate obesity. Diabetologia. PMID 26376797 DOI: 10.1007/S00125-015-3767-5  0.593
2015 Kabir M, Iyer MS, Richey JM, Woolcott OO, Asare Bediako I, Wu Q, Kim SP, Stefanovski D, Kolka CM, Hsu IR, Catalano KJ, Chiu JD, Ionut V, Bergman RN. CB1R antagonist increases hepatic insulin clearance in fat-fed dogs likely via upregulation of liver adiponectin receptors. American Journal of Physiology. Endocrinology and Metabolism. 309: E747-58. PMID 26306598 DOI: 10.1152/Ajpendo.00196.2015  0.848
2015 Rojas JM, Matsen ME, Mundinger TO, Morton GJ, Stefanovski D, Bergman RN, Kaiyala KJ, Taborsky GJ, Schwartz MW. Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response. Molecular Metabolism. 4: 561-8. PMID 26266088 DOI: 10.1016/J.Molmet.2015.05.005  0.727
2015 Broussard JL, Kolka CM, Castro AV, Asare Bediako I, Paszkiewicz RL, Szczepaniak EW, Szczepaniak LS, Knutson KL, Kim SP, Bergman RN. Elevated nocturnal NEFA are an early signal for hyperinsulinaemic compensation during diet-induced insulin resistance in dogs. Diabetologia. PMID 26254577 DOI: 10.1007/S00125-015-3721-6  0.763
2015 Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, Ionut V, Zheng D, Hsu IR, Catalano KJ, Chiu JD, ... ... Bergman RN, et al. Corrections: High-Fat Diet-Induced Insulin Resistance does not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets. Plos One. 10: e0131033. PMID 26075612 DOI: 10.1371/journal.pone.0131033  0.839
2015 Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, Ionut V, Zheng D, Hsu IR, Catalano KJ, Chiu JD, ... ... Bergman RN, et al. High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. Plos One. 10: e0123558. PMID 25855974 DOI: 10.1371/Journal.Pone.0123558  0.857
2015 Kolka CM, Richey JM, Castro AV, Broussard JL, Ionut V, Bergman RN. Lipid-induced insulin resistance does not impair insulin access to skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 308: E1001-9. PMID 25852002 DOI: 10.1152/Ajpendo.00015.2015  0.829
2015 Woolcott OO, Ader M, Bergman RN. Glucose homeostasis during short-term and prolonged exposure to high altitudes. Endocrine Reviews. 36: 149-73. PMID 25675133 DOI: 10.1210/er.2014-1063  0.45
2015 Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, ... ... Bergman RN, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 518: 197-206. PMID 25673413 DOI: 10.1038/Nature14177  0.37
2015 Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, ... ... Bergman RN, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518: 187-96. PMID 25673412 DOI: 10.1038/Nature14132  0.45
2015 Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, ... ... Bergman RN, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/Journal.Pgen.1004876  0.323
2015 Palmer ND, Goodarzi MO, Langefeld CD, Wang N, Guo X, Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, Haritunians T, Ziegler JT, Williams AH, Stefanovski D, Cui J, ... ... Bergman RN, et al. Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 64: 1853-66. PMID 25524916 DOI: 10.2337/Db14-0732  0.687
2015 Kolka CM, Castro AV, Kirkman EL, Bergman RN. Modest hyperglycemia prevents interstitial dispersion of insulin in skeletal muscle. Metabolism: Clinical and Experimental. 64: 330-7. PMID 25468139 DOI: 10.1016/j.metabol.2014.10.036  0.613
2015 Palmer ND, Stevens RD, Antinozzi PA, Anderson A, Bergman RN, Wagenknecht LE, Newgard CB, Bowden DW. Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study. The Journal of Clinical Endocrinology and Metabolism. 100: E463-8. PMID 25423564 DOI: 10.1210/Jc.2014-2357  0.531
2015 Castro AV, Woolcott OO, Iyer MS, Kabir M, Ionut V, Stefanovski D, Kolka CM, Szczepaniak LS, Szczepaniak EW, Asare-Bediako I, Paszkiewicz RL, Broussard JL, Kim SP, Kirkman EL, Rios HC, ... ... Bergman RN, et al. Increase in visceral fat per se does not induce insulin resistance in the canine model. Obesity (Silver Spring, Md.). 23: 105-11. PMID 25322680 DOI: 10.1002/Oby.20906  0.87
2015 Rojas JM, Matsen ME, Mundinger TO, Morton GJ, Stefanovski D, Bergman RN, Kaiyala KJ, Taborsky GJ, Schwartz MW. Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response Molecular Metabolism. DOI: 10.1016/j.molmet.2015.05.005  0.526
2015 Broussard JL, Kolka CM, Castro AVB, Asare Bediako I, Paszkiewicz RL, Szczepaniak EW, Szczepaniak LS, Knutson KL, Kim SP, Bergman RN. Elevated nocturnal NEFA are an early signal for hyperinsulinaemic compensation during diet-induced insulin resistance in dogs Diabetologia. DOI: 10.1007/s00125-015-3721-6  0.706
2014 Chiu S, Williams PT, Dawson T, Bergman RN, Stefanovski D, Watkins SM, Krauss RM. Diets high in protein or saturated fat do not affect insulin sensitivity or plasma concentrations of lipids and lipoproteins in overweight and obese adults. The Journal of Nutrition. 144: 1753-9. PMID 25332473 DOI: 10.3945/Jn.114.197624  0.708
2014 Castro AV, Kolka CM, Kim SP, Bergman RN. Obesity, insulin resistance and comorbidities? Mechanisms of association. Arquivos Brasileiros De Endocrinologia E Metabologia. 58: 600-9. PMID 25211442 DOI: 10.1590/0004-2730000003223  0.7
2014 Ionut V, Castro AV, Woolcott OO, Stefanovski D, Iyer MS, Broussard JL, Burch M, Elazary R, Kolka CM, Mkrtchyan H, Bediako IA, Bergman RN. Hepatic portal vein denervation impairs oral glucose tolerance but not exenatide's effect on glycemia. American Journal of Physiology. Endocrinology and Metabolism. 307: E644-52. PMID 25117408 DOI: 10.1152/Ajpendo.00244.2014  0.834
2014 Bergman RN, Stefanovski D, Kim SP. Systems analysis and the prediction and prevention of Type 2 diabetes mellitus. Current Opinion in Biotechnology. 28: 165-70. PMID 24976265 DOI: 10.1016/J.Copbio.2014.05.007  0.671
2014 Woolcott OO, Castillo OA, Gutierrez C, Elashoff RM, Stefanovski D, Bergman RN. Inverse association between diabetes and altitude: a cross-sectional study in the adult population of the United States. Obesity (Silver Spring, Md.). 22: 2080-90. PMID 24890677 DOI: 10.1002/Oby.20800  0.489
2014 Svensson PA, Wahlstrand B, Olsson M, Froguel P, Falchi M, Bergman RN, McTernan PG, Hedner T, Carlsson LM, Jacobson P. CDKN2B expression and subcutaneous adipose tissue expandability: possible influence of the 9p21 atherosclerosis locus. Biochemical and Biophysical Research Communications. 446: 1126-31. PMID 24680834 DOI: 10.1016/J.Bbrc.2014.03.075  0.3
2014 Ionut V, Castro AV, Woolcott OO, Stefanovski D, Iyer MS, Broussard JL, Mkrtchyan H, Burch M, Elazary R, Kirkman E, Bergman RN. Essentiality of portal vein receptors in hypoglycemic counterregulation: direct proof via denervation in male canines. Endocrinology. 155: 1247-54. PMID 24428530 DOI: 10.1210/En.2013-1794  0.831
2014 Ader M, Stefanovski D, Richey JM, Kim SP, Kolka CM, Ionut V, Kabir M, Bergman RN. Failure of homeostatic model assessment of insulin resistance to detect marked diet-induced insulin resistance in dogs. Diabetes. 63: 1914-9. PMID 24353184 DOI: 10.2337/Db13-1215  0.879
2014 Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, ... ... Bergman RN, et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 63: 2158-71. PMID 24296717 DOI: 10.2337/Db13-0949  0.52
2014 Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, ... ... Bergman RN, et al. Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring, Md.). 22: 1157-64. PMID 24124113 DOI: 10.1002/Oby.20639  0.541
2014 Ader M, Stefanovski D, Kim SP, Richey JM, Ionut V, Catalano KJ, Hucking K, Ellmerer M, Van Citters G, Hsu IR, Chiu JD, Woolcott OO, Harrison LN, Zheng D, Lottati M, ... ... Bergman RN, et al. Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog. Obesity (Silver Spring, Md.). 22: 1238-45. PMID 24123967 DOI: 10.1002/Oby.20625  0.857
2014 Castro AVB, Nunes VdS, Ionut V, Bergman RN, Dib RE. Is visceral fat a better predictor of the incidence of impaired glucose tolerance or type 2 diabetes mellitus than subcutaneous abdominal fat: a systematic review and meta-analysis of cohort studies. Peerj. DOI: 10.7287/Peerj.Preprints.199V1  0.734
2014 Castro AVB, Kolka CM, Kim SP, Bergman RN. Obesity, Insulin resistance and comorbidities - mechanisms of association | Obesidade, Resistência à insulina e comorbidades - mecanismos de associação Arquivos Brasileiros De Endocrinologia E Metabologia. 58: 600-609. DOI: 10.1590/0004-2730000003223  0.669
2013 Morton GJ, Matsen ME, Bracy DP, Meek TH, Nguyen HT, Stefanovski D, Bergman RN, Wasserman DH, Schwartz MW. FGF19 action in the brain induces insulin-independent glucose lowering. The Journal of Clinical Investigation. 123: 4799-808. PMID 24084738 DOI: 10.1172/Jci70710  0.719
2013 Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, ... ... Bergman RN, et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 62: 3589-98. PMID 23835345 DOI: 10.2337/Db13-0128  0.518
2013 Ionut V, Burch M, Youdim A, Bergman RN. Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity (Silver Spring, Md.). 21: 1093-103. PMID 23512841 DOI: 10.1002/Oby.20364  0.702
2013 Ahlin S, Sjöholm K, Jacobson P, Andersson-Assarsson JC, Walley A, Tordjman J, Poitou C, Prifti E, Jansson PA, Borén J, Sjöström L, Froguel P, Bergman RN, Carlsson LM, Olsson B, et al. Macrophage gene expression in adipose tissue is associated with insulin sensitivity and serum lipid levels independent of obesity. Obesity (Silver Spring, Md.). 21: E571-6. PMID 23512687 DOI: 10.1002/Oby.20443  0.398
2013 Kolka CM, Bergman RN. The endothelium in diabetes: its role in insulin access and diabetic complications. Reviews in Endocrine & Metabolic Disorders. 14: 13-9. PMID 23306780 DOI: 10.1007/s11154-012-9233-5  0.529
2013 Lee CC, Haffner SM, Wagenknecht LE, Lorenzo C, Norris JM, Bergman RN, Stefanovski D, Anderson AM, Rotter JI, Goodarzi MO, Hanley AJ. Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care. 36: 901-7. PMID 23223351 DOI: 10.2337/Dc12-1316  0.731
2012 Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, ... ... Bergman RN, et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics. 44: 991-1005. PMID 22885924 DOI: 10.1038/Ng.2385  0.442
2012 Miller MR, Pereira RI, Langefeld CD, Lorenzo C, Rotter JI, Chen YD, Bergman RN, Wagenknecht LE, Norris JM, Fingerlin TE. Levels of free fatty acids (FFA) are associated with insulin resistance but do not explain the relationship between adiposity and insulin resistance in Hispanic Americans: the IRAS Family Study. The Journal of Clinical Endocrinology and Metabolism. 97: 3285-91. PMID 22761463 DOI: 10.1210/Jc.2012-1318  0.545
2012 Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, ... ... Bergman RN, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/Journal.Pgen.1002741  0.312
2012 Bergman RN. Obesity, insulin resistance, and the pathway to type 2 diabetes Bmc Proceedings. 6: 1-1. PMID 22676146 DOI: 10.1186/1753-6561-6-S3-O1  0.648
2012 Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, ... ... Bergman RN, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature Genetics. 44: 659-69. PMID 22581228 DOI: 10.1038/Ng.2274  0.579
2012 Rowe MW, Bergman RN, Wagenknecht LE, Kolberg JA. Performance of a multi-marker diabetes risk score in the Insulin Resistance Atherosclerosis Study (IRAS), a multi-ethnic US cohort. Diabetes/Metabolism Research and Reviews. 28: 519-26. PMID 22492485 DOI: 10.1002/dmrr.2305  0.446
2012 Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... Bergman RN, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607  0.4
2012 Stefanovski D, Youn JH, Rees M, Watanabe RM, Ader M, Ionut V, Jackson AU, Boehnke M, Collins FS, Bergman RN. Estimating hepatic glucokinase activity using a simple model of lactate kinetics. Diabetes Care. 35: 1015-20. PMID 22456868 DOI: 10.2337/Dc11-1540  0.795
2012 Watkins SM, Rowe MW, Kolberg JA, Wagenknecht LE, Bergman RN. Biomarker models as surrogates for the disposition index in the Insulin Resistance Atherosclerosis Study. Diabetic Medicine : a Journal of the British Diabetic Association. 29: 1399-406. PMID 22413950 DOI: 10.1111/j.1464-5491.2012.03625.x  0.598
2012 Kim SP, Woolcott OO, Hsu IR, Stefanoski D, Harrison LN, Zheng D, Lottati M, Kolka C, Catalano KJ, Chiu JD, Kabir M, Ionut V, Bergman RN, Richey JM. CB(1) antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs. American Journal of Physiology. Endocrinology and Metabolism. 302: E1261-8. PMID 22374758 DOI: 10.1152/Ajpendo.00496.2011  0.864
2012 Alonso LC, Watanabe Y, Stefanovski D, Lee EJ, Singamsetty S, Romano LC, Zou B, Garcia-Ocaña A, Bergman RN, O'Donnell CP. Simultaneous measurement of insulin sensitivity, insulin secretion, and the disposition index in conscious unhandled mice. Obesity (Silver Spring, Md.). 20: 1403-12. PMID 22331130 DOI: 10.1038/Oby.2012.36  0.736
2012 Woolcott OO, Bergman RN, Richey JM, Kirkman EL, Harrison LN, Ionut V, Lottati M, Zheng D, Hsu IR, Stefanovski D, Kabir M, Kim SP, Catalano KJ, Chiu JD, Chow RH. Simplified method to isolate highly pure canine pancreatic islets. Pancreas. 41: 31-8. PMID 21792087 DOI: 10.1097/Mpa.0B013E318221Fd0E  0.808
2012 Stefanovski D, Bergman RN. Response to comment on: Stefanovski et al. Estimating hepatic glucokinase activity using a simple model of lactate kinetics. Diabetes Care 2012;35:1015-1020 Diabetes Care. 35: e91. DOI: 10.2337/Dc12-1253  0.489
2011 Ionut V, Bergman RN. Mechanisms responsible for excess weight loss after bariatric surgery. Journal of Diabetes Science and Technology. 5: 1263-82. PMID 22027328 DOI: 10.1177/193229681100500536  0.713
2011 Kabir M, Stefanovski D, Hsu IR, Iyer M, Woolcott OO, Zheng D, Catalano KJ, Chiu JD, Kim SP, Harrison LN, Ionut V, Lottati M, Bergman RN, Richey JM. Large size cells in the visceral adipose depot predict insulin resistance in the canine model. Obesity (Silver Spring, Md.). 19: 2121-9. PMID 21836643 DOI: 10.1038/Oby.2011.254  0.852
2011 Hanley AJ, Wagenknecht LE, Norris JM, Bergman R, Anderson A, Chen YI, Lorenzo C, Haffner SM. Adiponectin and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care. 34: 2231-6. PMID 21816973 DOI: 10.2337/Dc11-0531  0.482
2011 Stefanovski D, Richey JM, Woolcott O, Lottati M, Zheng D, Harrison LN, Ionut V, Kim SP, Hsu I, Bergman RN. Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA. Plos One. 6: e18134. PMID 21479217 DOI: 10.1371/Journal.Pone.0018134  0.877
2011 Bergman RN, Stefanovski D, Buchanan TA, Sumner AE, Reynolds JC, Sebring NG, Xiang AH, Watanabe RM. A better index of body adiposity. Obesity (Silver Spring, Md.). 19: 1083-9. PMID 21372804 DOI: 10.1038/Oby.2011.38  0.55
2010 Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, ... ... Bergman RN, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics. 42: 949-60. PMID 20935629 DOI: 10.1038/Ng.685  0.318
2010 Lorenzo C, Wagenknecht LE, Rewers MJ, Karter AJ, Bergman RN, Hanley AJ, Haffner SM. Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care. 33: 2098-103. PMID 20805282 DOI: 10.2337/dc10-0165  0.476
2010 Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, ... ... Bergman RN, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics. 42: 579-89. PMID 20581827 DOI: 10.1038/Ng.609  0.329
2010 Hsu IR, Zuniga E, Bergman RN. Pulsatile changes in free fatty acids augment hepatic glucose production and preserves peripheral glucose homeostasis. American Journal of Physiology. Endocrinology and Metabolism. 299: E131-6. PMID 20424137 DOI: 10.1152/Ajpendo.00427.2009  0.83
2010 Catalano KJ, Stefanovski D, Bergman RN. Critical role of the mesenteric depot versus other intra-abdominal adipose depots in the development of insulin resistance in young rats. Diabetes. 59: 1416-23. PMID 20299478 DOI: 10.2337/Db08-0675  0.849
2010 Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, et al. Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes. 59: 1266-75. PMID 20185807 DOI: 10.2337/Db09-1568  0.629
2010 Bouche C, Lopez X, Fleischman A, Cypess AM, O'Shea S, Stefanovski D, Bergman RN, Rogatsky E, Stein DT, Kahn CR, Kulkarni RN, Goldfine AB. Insulin enhances glucose-stimulated insulin secretion in healthy humans. Proceedings of the National Academy of Sciences of the United States of America. 107: 4770-5. PMID 20176932 DOI: 10.1073/Pnas.1000002107  0.741
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Bergman RN, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/Ng.520  0.564
2010 Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, ... ... Bergman RN, et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nature Genetics. 42: 142-8. PMID 20081857 DOI: 10.1038/Ng.521  0.473
2010 Ruchat SM, Rankinen T, Weisnagel SJ, Rice T, Rao DC, Bergman RN, Bouchard C, Pérusse L. Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia. 53: 679-89. PMID 20043145 DOI: 10.1007/S00125-009-1630-2  0.355
2010 Kolka CM, Harrison LN, Lottati M, Chiu JD, Kirkman EL, Bergman RN. Diet-induced obesity prevents interstitial dispersion of insulin in skeletal muscle. Diabetes. 59: 619-26. PMID 19959760 DOI: 10.2337/Db09-0839  0.879
2010 Zheng D, Ionut V, Mooradian V, Stefanovski D, Bergman RN. Portal glucose infusion-glucose clamp measures hepatic influence on postprandial systemic glucose appearance as well as whole body glucose disposal. American Journal of Physiology. Endocrinology and Metabolism. 298: E346-53. PMID 19934401 DOI: 10.1152/Ajpendo.00280.2009  0.823
2010 Palmer ND, Langefeld CD, Ziegler JT, Hsu F, Haffner SM, Fingerlin T, Norris JM, Chen YI, Rich SS, Haritunians T, Taylor KD, Bergman RN, Rotter JI, Bowden DW. Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Diabetologia. 53: 281-9. PMID 19902172 DOI: 10.1007/S00125-009-1586-2  0.578
2010 Ionut V, Liu H, Mooradian V, Castro AV, Kabir M, Stefanovski D, Zheng D, Kirkman EL, Bergman RN. Novel canine models of obese prediabetes and mild type 2 diabetes. American Journal of Physiology. Endocrinology and Metabolism. 298: E38-48. PMID 19843874 DOI: 10.1152/Ajpendo.00466.2009  0.822
2010 Miller MR, Zhang W, Sibbel SP, Langefeld CD, Bowden DW, Haffner SM, Bergman RN, Norris JM, Fingerlin TE. Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study. Obesity (Silver Spring, Md.). 18: 555-62. PMID 19798070 DOI: 10.1038/Oby.2009.303  0.463
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, ... ... Bergman RN, et al. Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk Nature Genetics. 42: 464-464. DOI: 10.1038/Ng0510-464A  0.389
2009 Bergman RN. The two-edged sword. Endocrinología Y NutricióN : óRgano De La Sociedad EspañOla De Endocrinología Y NutricióN. 56: 5-7. PMID 20629221 DOI: 10.1016/S1575-0922(09)73507-7  0.641
2009 Hanley AJ, Wagenknecht LE, Norris JM, Bryer-Ash M, Chen YI, Anderson AM, Bergman R, Haffner SM. Insulin resistance, beta cell dysfunction and visceral adiposity as predictors of incident diabetes: the Insulin Resistance Atherosclerosis Study (IRAS) Family study. Diabetologia. 52: 2079-86. PMID 19641896 DOI: 10.1007/S00125-009-1464-Y  0.571
2009 Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, ... ... Bergman RN, et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. Plos Genetics. 5: e1000508. PMID 19557161 DOI: 10.1371/Journal.Pgen.1000508  0.367
2009 Chiu JD, Kolka CM, Richey JM, Harrison LN, Zuniga E, Kirkman EL, Bergman RN. Experimental hyperlipidemia dramatically reduces access of insulin to canine skeletal muscle. Obesity (Silver Spring, Md.). 17: 1486-92. PMID 19521354 DOI: 10.1038/Oby.2009.165  0.857
2009 Rich SS, Goodarzi MO, Palmer ND, Langefeld CD, Ziegler J, Haffner SM, Bryer-Ash M, Norris JM, Taylor KD, Haritunians T, Rotter JI, Chen YD, Wagenknecht LE, Bowden DW, Bergman RN. A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Diabetologia. 52: 1326-33. PMID 19430760 DOI: 10.1007/S00125-009-1373-0  0.588
2009 Richey JM, Woolcott OO, Stefanovski D, Harrison LN, Zheng D, Lottati M, Hsu IR, Kim SP, Kabir M, Catalano KJ, Chiu JD, Ionut V, Kolka C, Mooradian V, Bergman RN. Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs. American Journal of Physiology. Endocrinology and Metabolism. 296: E1311-8. PMID 19366874 DOI: 10.1152/Ajpendo.90972.2008  0.783
2009 Lottati M, Kolka CM, Stefanovski D, Kirkman EL, Bergman RN. Greater omentectomy improves insulin sensitivity in nonobese dogs. Obesity (Silver Spring, Md.). 17: 674-80. PMID 19214178 DOI: 10.1038/Oby.2008.642  0.882
2009 Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, ... ... Bergman RN, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nature Genetics. 41: 25-34. PMID 19079261 DOI: 10.1038/Ng.287  0.309
2009 Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, ... ... Bergman RN, et al. Variants in MTNR1B influence fasting glucose levels. Nature Genetics. 41: 77-81. PMID 19060907 DOI: 10.1038/Ng.290  0.4
2009 Zheng D, Ionut V, Mooradian V, Stefanovski D, Bergman RN. Exenatide sensitizes insulin-mediated whole-body glucose disposal and promotes uptake of exogenous glucose by the liver. Diabetes. 58: 352-9. PMID 19011168 DOI: 10.2337/Db08-0875  0.839
2008 Periwal V, Chow CC, Bergman RN, Ricks M, Vega GL, Sumner AE. Evaluation of quantitative models of the effect of insulin on lipolysis and glucose disposal. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1089-96. PMID 18685069 DOI: 10.1152/ajpregu.90426.2008  0.606
2008 Hücking K, Watanabe RM, Stefanovski D, Bergman RN. OGTT-derived measures of insulin sensitivity are confounded by factors other than insulin sensitivity itself. Obesity (Silver Spring, Md.). 16: 1938-45. PMID 18670420 DOI: 10.1038/Oby.2008.336  0.749
2008 Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrù M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, ... ... Bergman RN, et al. Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. The Journal of Clinical Investigation. 118: 2620-8. PMID 18521185 DOI: 10.1172/Jci34566  0.464
2008 Ionut V, Zheng D, Stefanovski D, Bergman RN. Exenatide can reduce glucose independent of islet hormones or gastric emptying. American Journal of Physiology. Endocrinology and Metabolism. 295: E269-77. PMID 18492781 DOI: 10.1152/Ajpendo.90222.2008  0.818
2008 Ader M, Garvey WT, Phillips LS, Nemeroff CB, Gharabawi G, Mahmoud R, Greenspan A, Berry SA, Musselman DL, Morein J, Zhu Y, Mao L, Bergman RN. Ethnic heterogeneity in glucoregulatory function during treatment with atypical antipsychotics in patients with schizophrenia. Journal of Psychiatric Research. 42: 1076-85. PMID 18295798 DOI: 10.1016/J.Jpsychires.2008.01.004  0.482
2008 Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW. Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes. 57: 1093-100. PMID 18252897 DOI: 10.2337/Db07-1169  0.484
2008 Chiu JD, Richey JM, Harrison LN, Zuniga E, Kolka CM, Kirkman E, Ellmerer M, Bergman RN. Direct administration of insulin into skeletal muscle reveals that the transport of insulin across the capillary endothelium limits the time course of insulin to activate glucose disposal. Diabetes. 57: 828-35. PMID 18223011 DOI: 10.2337/Db07-1444  0.851
2008 Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM. Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes. 57: 1048-56. PMID 18162503 DOI: 10.2337/Db07-0848  0.456
2008 Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Bergman RN, Goodarzi MO, Rotter JI, Bowden DW. Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. The Journal of Clinical Endocrinology and Metabolism. 93: 304-9. PMID 17971425 DOI: 10.1210/Jc.2007-1225  0.403
2007 Bergman RN. [Orchestration of homeostasis of glucose metabolism]. JournéEs Annuelles De DiabéTologie De L'HôTel-Dieu. 127-38. PMID 18610764  0.319
2007 Hsu IR, Kim SP, Kabir M, Bergman RN. Metabolic syndrome, hyperinsulinemia, and cancer. The American Journal of Clinical Nutrition. 86: s867-71. PMID 18265480 DOI: 10.1093/Ajcn/86.3.867S  0.874
2007 Hücking K, Hsu IR, Ionut V, Bergman RN. Deconvolution as a novel approach to analyze moment-to-moment free fatty acid release. Obesity (Silver Spring, Md.). 15: 2416-23. PMID 17925467 DOI: 10.1038/Oby.2007.287  0.779
2007 Cruz ML, Weigensberg MJ, Bergman RN, Goran MI. Frequency of hypoglycaemia during the intravenous glucose tolerance test in overweight children. International Journal of Pediatric Obesity : Ijpo : An Official Journal of the International Association For the Study of Obesity. 2: 122-5. PMID 17763019 DOI: 10.1080/17477160601181589  0.59
2007 Bergman RN. Orchestration of glucose homeostasis: from a small acorn to the California oak. Diabetes. 56: 1489-501. PMID 17526912 DOI: 10.2337/db07-9903  0.363
2007 Sale MM, Hsu FC, Palmer ND, Gordon CJ, Keene KL, Borgerink HM, Sharma AJ, Bergman RN, Taylor KD, Saad MF, Norris JM. The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study. Bmc Endocrine Disorders. 7: 1. PMID 17397545 DOI: 10.1186/1472-6823-7-1  0.451
2007 Bergman RN, Kim SP, Hsu IR, Catalano KJ, Chiu JD, Kabir M, Richey JM, Ader M. Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. The American Journal of Medicine. 120: S3-8; discussion S29. PMID 17296343 DOI: 10.1016/J.Amjmed.2006.11.012  0.865
2007 Kim SP, Ellmerer M, Kirkman EL, Bergman RN. Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model. American Journal of Physiology. Endocrinology and Metabolism. 292: E1581-9. PMID 17284579 DOI: 10.1152/Ajpendo.00351.2006  0.793
2007 Kim SP, Catalano KJ, Hsu IR, Chiu JD, Richey JM, Bergman RN. Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. American Journal of Physiology. Endocrinology and Metabolism. 292: E1590-8. PMID 17264230 DOI: 10.1152/Ajpendo.00669.2006  0.883
2007 Shtir C, Nagakawa IS, Duren WL, Conneely KN, Scott LJ, Silander K, Valle TT, Tuomilehto J, Buchanan TA, Bergman RN, Collins FS, Boehnke M, Watanabe RM. Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q. Human Heredity. 63: 17-25. PMID 17179727 DOI: 10.1159/000097927  0.421
2007 Goodarzi MO, Taylor KD, Guo X, Hokanson JE, Haffner SM, Cui J, Chen YD, Wagenknecht LE, Bergman RN, Rotter JI. Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype. The Journal of Clinical Endocrinology and Metabolism. 92: 293-6. PMID 17032721 DOI: 10.1210/Jc.2006-1195  0.545
2007 Harrison LN, Stefanovski D, Woolcott O, Lottati M, Zheng D, Ionut V, Kim SP, Hsu I, Kabir M, Catalano KJ, Chiu JD, Bergman RN, Richey JM. Cannabinoid receptor antagonist rimonabant prevents weight gain in dogs on a high fat diet The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A694-D  0.771
2006 Nittala A, Ghosh S, Stefanovski D, Bergman R, Wang X. Dimensional analysis of MINMOD leads to definition of the disposition index of glucose regulation and improved simulation algorithm. Biomedical Engineering Online. 5: 44. PMID 16842624 DOI: 10.1186/1475-925X-5-44  0.618
2006 Ellmerer M, Hamilton-Wessler M, Kim SP, Huecking K, Kirkman E, Chiu J, Richey J, Bergman RN. Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake. Diabetes. 55: 1769-75. PMID 16731841 DOI: 10.2337/Db05-1509  0.881
2006 Guo X, Saad MF, Langefeld CD, Williams AH, Cui J, Taylor KD, Norris JM, Jinagouda S, Darwin CH, Mitchell BD, Bergman RN, Sutton B, Chen YD, Wagenknecht LE, Bowden DW, et al. Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study. Diabetes. 55: 1723-30. PMID 16731835 DOI: 10.2337/Db05-0428  0.305
2006 Ionut V, Liberty IF, Hucking K, Lottati M, Stefanovski D, Zheng D, Bergman RN. Exogenously imposed postprandial-like rises in systemic glucose and GLP-1 do not produce an incretin effect, suggesting an indirect mechanism of GLP-1 action. American Journal of Physiology. Endocrinology and Metabolism. 291: E779-85. PMID 16720628 DOI: 10.1152/Ajpendo.00106.2005  0.87
2006 Bergman RN, Kim SP, Catalano KJ, Hsu IR, Chiu JD, Kabir M, Hucking K, Ader M. Why visceral fat is bad: mechanisms of the metabolic syndrome. Obesity (Silver Spring, Md.). 14: 16S-19S. PMID 16642958 DOI: 10.1038/Oby.2006.277  0.847
2006 Palmer ND, Langefeld CD, Campbell JK, Williams AH, Saad M, Norris JM, Haffner SM, Rotter JI, Wagenknecht LE, Bergman RN, Rich SS, Bowden DW. Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 55: 911-8. PMID 16567510 DOI: 10.2337/Diabetes.55.04.06.Db05-0813  0.486
2006 Ionut V, Stefanovski D, Lottati M, Kirkman E, Bergman RN. 148 PORTAL GLUCAGON-LIKE PROTEIN 1 PRODUCES AN INSULIN-INDEPENDENT REDUCTION IN GLYCEMIA BY INCREASING PERIPHERAL GLUCOSE DISPOSAL, WITHOUT CHANGING HEPATIC GLUCOSE BALANCE. Journal of Investigative Medicine. 54: S105.4-S105. DOI: 10.2310/6650.2005.X0004.147  0.854
2005 Rich SS, Bergman RN. The genetic basis of glucose homeostasis. Current Diabetes Reviews. 1: 221-6. PMID 18220598 DOI: 10.2174/157339905774574293  0.564
2005 Bergman RN. Minimal model: perspective from 2005. Hormone Research. 64: 8-15. PMID 16439839 DOI: 10.1159/000089312  0.544
2005 Mohlke KL, Jackson AU, Scott LJ, Peck EC, Suh YD, Chines PS, Watanabe RM, Buchanan TA, Conneely KN, Erdos MR, Narisu N, Enloe S, Valle TT, Tuomilehto J, Bergman RN, et al. Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Human Genetics. 118: 245-54. PMID 16142453 DOI: 10.1007/S00439-005-0046-4  0.346
2005 Ukkola O, Santaniemi M, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Kesäniemi YA, Bouchard C. Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE family study and Oulu diabetic study. Annals of Medicine. 37: 141-50. PMID 16028335 DOI: 10.1080/07853890510007241  0.425
2005 Sumner AE, Vega GL, Genovese DJ, Finley KB, Bergman RN, Boston RC. Normal triglyceride levels despite insulin resistance in African Americans: role of lipoprotein lipase. Metabolism: Clinical and Experimental. 54: 902-9. PMID 15988699 DOI: 10.1016/J.Metabol.2005.03.001  0.509
2005 Teran-Garcia M, Santoro N, Rankinen T, Bergeron J, Rice T, Leon AS, Rao DC, Skinner JS, Bergman RN, Després JP, Bouchard C. Hepatic lipase gene variant -514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study. Diabetes. 54: 2251-5. PMID 15983229 DOI: 10.2337/Diabetes.54.7.2251  0.309
2005 Mohlke KL, Skol AD, Scott LJ, Valle TT, Bergman RN, Tuomilehto J, Boehnke M, Collins FS. Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns. Molecular Genetics and Metabolism. 85: 323-7. PMID 15936967 DOI: 10.1016/J.Ymgme.2005.04.011  0.393
2005 An P, Teran-Garcia M, Rice T, Rankinen T, Weisnagel SJ, Bergman RN, Boston RC, Mandel S, Stefanovski D, Leon AS, Skinner JS, Rao DC, Bouchard C. Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study. Diabetologia. 48: 1142-9. PMID 15868134 DOI: 10.1007/S00125-005-1769-4  0.698
2005 Boston RC, Moate PJ, Stefanovski D, Sumner AE, Bergman RN. AKA-Glucose: a program for kinetic and epidemiological analysis of frequently sampled intravenous glucose tolerance test data using database technology. Diabetes Technology & Therapeutics. 7: 298-307. PMID 15857232 DOI: 10.1089/Dia.2005.7.298  0.645
2005 Ionut V, Hucking K, Liberty IF, Bergman RN. Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose and stimulate counter-regulatory hormones. Diabetologia. 48: 967-75. PMID 15830188 DOI: 10.1007/S00125-005-1709-3  0.805
2005 Bergman RN, Ader M. Atypical antipsychotics and glucose homeostasis. The Journal of Clinical Psychiatry. 66: 504-14. PMID 15816794 DOI: 10.4088/Jcp.V66N0414  0.566
2005 Karter AJ, D'Agostino RB, Mayer-Davis EJ, Wagenknecht LE, Hanley AJG, Hamman RF, Bergman R, Saad MF, Haffner SM. Abdominal obesity predicts declining insulin sensitivity in non-obese normoglycaemics: The Insulin Resistance Atherosclerosis Study (IRAS) Diabetes, Obesity and Metabolism. 7: 230-238. PMID 15811139 DOI: 10.1111/J.1463-1326.2004.00441.X  0.465
2005 Catalano KJ, Bergman RN, Ader M. Increased susceptibility to insulin resistance associated with abdominal obesity in aging rats. Obesity Research. 13: 11-20. PMID 15761159 DOI: 10.1038/Oby.2005.4  0.831
2005 Ader M, Kim SP, Catalano KJ, Ionut V, Hucking K, Richey JM, Kabir M, Bergman RN. Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes. 54: 862-71. PMID 15734866 DOI: 10.2337/Diabetes.54.3.862  0.837
2005 Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Effects of exercise training on glucose homeostasis: the HERITAGE Family Study. Diabetes Care. 28: 108-14. PMID 15616242 DOI: 10.2337/Diacare.28.1.108  0.365
2005 Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Hedrick CC, Wagenknecht LE, Bergman RN. A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 54: 290-5. PMID 15616041 DOI: 10.2337/Diabetes.54.1.290  0.614
2005 Norris JM, Langefeld CD, Scherzinger AL, Rich SS, Bookman E, Beck SR, Saad MF, Haffner SM, Bergman RN, Bowden DW, Wagenknecht LE. Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study. International Journal of Obesity (2005). 29: 67-77. PMID 15534617 DOI: 10.1038/Sj.Ijo.0802793  0.303
2005 Kabir M, Catalano KJ, Ananthnarayan S, Kim SP, Van Citters GW, Dea MK, Bergman RN. Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 288: E454-61. PMID 15522994 DOI: 10.1152/Ajpendo.00203.2004  0.858
2005 Liberty IF, Ionut V, Kim SP, Ader M, Lottati M, Bergman RN. 165 HIV-PROTEASE INHIBITOR TREATMENT, A NEW CANINE EXPERIMENTAL MODEL OF INSULIN RESISTANCE: Journal of Investigative Medicine. 53: S106.5-S107. DOI: 10.2310/6650.2005.00005.164  0.883
2005 Ionut V, Liberty IF, Hucking K, Lottati M, Bergman RN. 162 DIRECT ACTION OF GLUCOSE AND GLUCAGON-LIKE PEPTIDE-1 ON THE PANCREAS MIGHT NOT BE RESPONSIBLE FOR A SIGNIFICANT PORTION OF THE INCRETIN RESPONSE DURING A MIXED MEAL Journal of Investigative Medicine. 53: S106.2-S106. DOI: 10.2310/6650.2005.00005.161  0.856
2004 Conneely KN, Silander K, Scott LJ, Mohlke KL, Lazaridis KN, Valle TT, Tuomilehto J, Bergman RN, Watanabe RM, Buchanan TA, Collins FS, Boehnke M. Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia. 47: 1782-8. PMID 15517149 DOI: 10.1007/S00125-004-1537-X  0.506
2004 Palmer ND, Bento JL, Mychaleckyj JC, Langefeld CD, Campbell JK, Norris JM, Haffner SM, Bergman RN, Bowden DW. Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 53: 3013-9. PMID 15504985 DOI: 10.2337/Diabetes.53.11.3013  0.545
2004 Ellmerer M, Kim SP, Hamilton-Wessler M, Hücking K, Kirkman E, Bergman RN. Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin-sensitive tissues. Diabetes. 53: 2741-7. PMID 15504953 DOI: 10.2337/Diabetes.53.11.2741  0.761
2004 Ionut V, Kirkman EL, Bergman RN. Investigation of the effect of acepromazine on intravenous glucose tolerance tests in dogs. American Journal of Veterinary Research. 65: 1124-7. PMID 15334847 DOI: 10.2460/Ajvr.2004.65.1124  0.807
2004 Sumner AE, Bergman RN, Vega GL, Genovese DJ, Cochran CS, Pacak K, Watanabe RM, Boston RC. The multiphasic profile of free fatty acids during the intravenous glucose tolerance test is unresponsive to exogenous insulin. Metabolism: Clinical and Experimental. 53: 1202-7. PMID 15334385 DOI: 10.1016/J.Metabol.2004.03.020  0.597
2004 Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Wagenknecht LE, Bergman RN. Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 53: 1866-75. PMID 15220212 DOI: 10.2337/Diabetes.53.7.1866  0.537
2004 Mitchell BD, Zaccaro D, Wagenknecht LE, Scherzinger AL, Bergman RN, Haffner SM, Hokanson J, Norris JM, Rotter JI, Saad MF. Insulin sensitivity, body fat distribution, and family diabetes history: the IRAS Family Study. Obesity Research. 12: 831-9. PMID 15166304 DOI: 10.1038/Oby.2004.100  0.504
2004 Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Lakka HM, Ukkola O, Boulé N, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Bouchard C. Leptin and leptin receptor gene polymorphisms and changes in glucose homeostasis in response to regular exercise in nondiabetic individuals: the HERITAGE family study. Diabetes. 53: 1603-8. PMID 15161768 DOI: 10.2337/Diabetes.53.6.1603  0.537
2004 Saad MF, Rewers M, Selby J, Howard G, Jinagouda S, Fahmi S, Zaccaro D, Bergman RN, Savage PJ, Haffner SM. Insulin resistance and hypertension: the Insulin Resistance Atherosclerosis study. Hypertension. 43: 1324-31. PMID 15123571 DOI: 10.1161/01.HYP.0000128019.19363.f9  0.579
2004 Rewers M, Zaccaro D, D'Agostino R, Haffner S, Saad MF, Selby JV, Bergman R, Savage P. Insulin sensitivity, insulinemia, and coronary artery disease: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 27: 781-7. PMID 14988302 DOI: 10.2337/Diacare.27.3.781  0.515
2004 Goran MI, Bergman RN, Avila Q, Watkins M, Ball GD, Shaibi GQ, Weigensberg MJ, Cruz ML. Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism. 89: 207-12. PMID 14715851 DOI: 10.1210/Jc.2003-031402  0.519
2004 Ionut V, Hucking K, Bergman RN. 156 PORTAL GLUCAGON-LIKE PEPTIDE-1 AND PORTAL GLUCOSE SYNERGIZE TO STIMULATE INSULIN SECRETION. Journal of Investigative Medicine. 52: S106.3-S106. DOI: 10.1136/Jim-52-Suppl1-156  0.807
2003 Bergman RN. The minimal model of glucose regulation: a biography. Advances in Experimental Medicine and Biology. 537: 1-19. PMID 14995025 DOI: 10.1007/978-1-4419-9019-8_1  0.344
2003 Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN. MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technology & Therapeutics. 5: 1003-15. PMID 14709204 DOI: 10.1089/152091503322641060  0.714
2003 Bergman RN. Insulin action and distribution of tissue blood flow. The Journal of Clinical Endocrinology and Metabolism. 88: 4556-8. PMID 14557421 DOI: 10.1210/jc.2003-031431  0.46
2003 Wagenknecht LE, Langefeld CD, Scherzinger AL, Norris JM, Haffner SM, Saad MF, Bergman RN. Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 52: 2490-6. PMID 14514631 DOI: 10.2337/Diabetes.52.10.2490  0.591
2003 Kim SP, Ellmerer M, Van Citters GW, Bergman RN. Primacy of hepatic insulin resistance in the development of the metabolic syndrome induced by an isocaloric moderate-fat diet in the dog. Diabetes. 52: 2453-60. PMID 14514627 DOI: 10.2337/Diabetes.52.10.2453  0.888
2003 Haffner SM, D'Agostino R, Festa A, Bergman RN, Mykkänen L, Karter A, Saad MF, Wagenknecht LE. Low insulin sensitivity (S(i) = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: is it associated with components of the metabolic syndrome and nontraditional risk factors? Diabetes Care. 26: 2796-803. PMID 14514582 DOI: 10.2337/diacare.26.10.2796  0.574
2003 Bergman RN, Zaccaro DJ, Watanabe RM, Haffner SM, Saad MF, Norris JM, Wagenknecht LE, Hokanson JE, Rotter JI, Rich SS. Minimal model-based insulin sensitivity has greater heritability and a different genetic basis than homeostasis model assessment or fasting insulin. Diabetes. 52: 2168-74. PMID 12882937 DOI: 10.2337/Diabetes.52.8.2168  0.621
2003 Ellmerer M, Hamilton-Wessler M, Kim SP, Dea MK, Kirkman E, Perianayagam A, Markussen J, Bergman RN. Mechanism of action in dogs of slow-acting insulin analog O346. The Journal of Clinical Endocrinology and Metabolism. 88: 2256-62. PMID 12727983 DOI: 10.1210/Jc.2002-021102  0.702
2003 Henkin L, Bergman RN, Bowden DW, Ellsworth DL, Haffner SM, Langefeld CD, Mitchell BD, Norris JM, Rewers M, Saad MF, Stamm E, Wagenknecht LE, Rich SS. Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Annals of Epidemiology. 13: 211-7. PMID 12684185 DOI: 10.1016/S1047-2797(02)00412-X  0.536
2003 An P, Hong Y, Weisnagel SJ, Rice T, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Chagnon YC, Bergman RN, Bouchard C, Rao DC. Genomic scan of glucose and insulin metabolism phenotypes: the HERITAGE Family Study. Metabolism: Clinical and Experimental. 52: 246-53. PMID 12601641 DOI: 10.1053/Meta.2003.50030  0.558
2003 Hücking K, Hamilton-Wessler M, Ellmerer M, Bergman RN. Burst-like control of lipolysis by the sympathetic nervous system in vivo. The Journal of Clinical Investigation. 111: 257-64. PMID 12531882 DOI: 10.1172/JCI14466  0.304
2003 Goran MI, Coronges K, Bergman RN, Cruz ML, Gower BA. Influence of family history of type 2 diabetes on insulin sensitivity in prepubertal children. The Journal of Clinical Endocrinology and Metabolism. 88: 192-5. PMID 12519851 DOI: 10.1210/Jc.2002-020917  0.499
2003 Ellmerer M, Bergman RN, Bodenlenz M, Pieber TR. Long-acting insulin analogues: What we learn from integrated physiology Collection of Czechoslovak Chemical Communications. 6: 15-19. DOI: 10.1135/Css200306015  0.46
2003 Ader M, Kim S, Catalano K, Ionut V, Hucking K, Richey J, Kabir M, Bergman R. P.2.093 Marked increase in adiposity during olanzapine vs risperidone treatment: Results of a placebo-controlled study in normal dogs European Neuropsychopharmacology. 13: S320-S321. DOI: 10.1016/S0924-977X(03)92046-3  0.785
2002 Resnick HE, Bergman RN, Henderson JA, Nez-Henderson P, Howard BV. Utility of a surrogate measure of insulin resistance in American Indians: the Strong Heart Study. Ethnicity & Disease. 12: 523-9. PMID 12477138  0.486
2002 Goran MI, Bergman RN, Cruz ML, Watanabe R. Insulin resistance and associated compensatory responses in african-american and Hispanic children. Diabetes Care. 25: 2184-90. PMID 12453958 DOI: 10.2337/Diacare.25.12.2184  0.567
2002 Bergman RN. Pathogenesis and prediction of diabetes mellitus: lessons from integrative physiology. The Mount Sinai Journal of Medicine, New York. 69: 280-90. PMID 12415321  0.48
2002 van Citters GW, Kabir M, Kim SP, Mittelman SD, Dea MK, Brubaker PL, Bergman RN. Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding. The Journal of Clinical Endocrinology and Metabolism. 87: 5191-8. PMID 12414891 DOI: 10.1210/Jc.2002-020002  0.853
2002 Cruz ML, Bergman RN, Goran MI. Unique effect of visceral fat on insulin sensitivity in obese Hispanic children with a family history of type 2 diabetes. Diabetes Care. 25: 1631-6. PMID 12196439 DOI: 10.2337/Diacare.25.9.1631  0.573
2002 Bergman RN, Finegood DT, Kahn SE. The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes. European Journal of Clinical Investigation. 32: 35-45. PMID 12028373 DOI: 10.1046/J.1365-2362.32.S3.5.X  0.519
2002 Hanley AJ, D'Agostino R, Wagenknecht LE, Saad MF, Savage PJ, Bergman R, Haffner SM. Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study. Diabetes. 51: 1263-70. PMID 11916954 DOI: 10.2337/diabetes.51.4.1263  0.524
2002 Dea MK, Hamilton-Wessler M, Ader M, Moore D, Schäffer L, Loftager M, Vølund A, Bergman RN. Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose uptake. Diabetes. 51: 762-9. PMID 11872677 DOI: 10.2337/Diabetes.51.3.762  0.607
2002 Mittelman SD, Van Citters GW, Kirkman EL, Bergman RN. Extreme insulin resistance of the central adipose depot in vivo. Diabetes. 51: 755-61. PMID 11872676 DOI: 10.2337/Diabetes.51.3.755  0.847
2002 Hamilton-Wessler M, Ader M, Dea MK, Moore D, Loftager M, Markussen J, Bergman RN. Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion. Diabetes. 51: 574-82. PMID 11872653 DOI: 10.2337/Diabetes.51.3.574  0.595
2002 Bergman RN, Ader M, Huecking K, Van Citters G. Accurate assessment of beta-cell function: the hyperbolic correction. Diabetes. 51: S212-20. PMID 11815482 DOI: 10.2337/Diabetes.51.2007.S212  0.827
2002 Marmarelis VZ, Mitsis GD, Huecking K, Bergman RN. Nonlinear modeling of the insulin-glucose dynamic relationship in dogs Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 224-225.  0.447
2001 Gresl TA, Colman RJ, Roecker EB, Havighurst TC, Huang Z, Allison DB, Bergman RN, Kemnitz JW. Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. American Journal of Physiology. Endocrinology and Metabolism. 281: E757-65. PMID 11551852 DOI: 10.1152/Ajpendo.2001.281.4.E757  0.584
2001 Hong Y, Weisnagel SJ, Rice T, Sun G, Mandel SA, Gu C, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bergman RN, Bouchard C, Rao DC. Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study. Clinical Genetics. 60: 22-30. PMID 11531966 DOI: 10.1034/J.1399-0004.2001.600104.X  0.593
2001 Goran MI, Bergman RN, Gower BA. Influence of total vs. visceral fat on insulin action and secretion in African American and white children. Obesity Research. 9: 423-31. PMID 11500522 DOI: 10.1038/Oby.2001.56  0.446
2001 Fosgerau K, Mittelman SD, Sunehag A, Dea MK, Lundgren K, Bergman RN. Lack of hepatic "interregulation" during inhibition of glycogenolysis in a canine model. American Journal of Physiology. Endocrinology and Metabolism. 281: E375-83. PMID 11440915 DOI: 10.1152/Ajpendo.2001.281.2.E375  0.427
2001 Mayer-Davis EJ, Levin S, Bergman RN, D'Agostino RB, Karter AJ, Saad MF. Insulin secretion, obesity, and potential behavioral influences: results from the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes/Metabolism Research and Reviews. 17: 137-45. PMID 11307179 DOI: 10.1002/Dmrr.185  0.579
2001 Douglas JA, Erdos MR, Watanabe RM, Braun A, Johnston CL, Oeth P, Mohlke KL, Valle TT, Ehnholm C, Buchanan TA, Bergman RN, Collins FS, Boehnke M, Tuomilehto J. The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences. Diabetes. 50: 886-90. PMID 11289057 DOI: 10.2337/Diabetes.50.4.886  0.391
2001 Hevener AL, Bergman RN, Donovan CM. Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus. Diabetes. 50: 399-403. PMID 11272153 DOI: 10.2337/Diabetes.50.2.399  0.434
2001 Bergman RN, Van Citters GW, Mittelman SD, Dea MK, Hamilton-Wessler M, Kim SP, Ellmerer M. Central role of the adipocyte in the metabolic syndrome. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 49: 119-26. PMID 11217141 DOI: 10.2310/6650.2001.34108  0.872
2000 Mittelman SD, Van Citters GW, Kim SP, Davis DA, Dea MK, Hamilton-Wessler M, Bergman RN. Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes. 49: 2116-25. PMID 11118015 DOI: 10.2337/Diabetes.49.12.2116  0.884
2000 Dea MK, Van Citters GW, Ader M, Mittelman SD, Sunehag AL, Bergman RN. Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity. Diabetes. 49: 2087-93. PMID 11118011 DOI: 10.2337/Diabetes.49.12.2087  0.837
2000 Caumo A, Bergman RN, Cobelli C. Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. The Journal of Clinical Endocrinology and Metabolism. 85: 4396-402. PMID 11095485 DOI: 10.1210/Jcem.85.11.6982  0.554
2000 Bergman RN, Ader M. Free fatty acids and pathogenesis of type 2 diabetes mellitus. Trends in Endocrinology and Metabolism: Tem. 11: 351-6. PMID 11042464 DOI: 10.1016/S1043-2760(00)00323-4  0.652
2000 Bergman RN. Non-esterified fatty acids and the liver: why is insulin secreted into the portal vein? Diabetologia. 43: 946-52. PMID 10952470 DOI: 10.1007/s001250051474  0.638
2000 Mittelman SD, Bergman RN. Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. American Journal of Physiology. Endocrinology and Metabolism. 279: E630-7. PMID 10950832 DOI: 10.1152/Ajpendo.2000.279.3.E630  0.587
2000 Getty L, Panteleon AE, Mittelman SD, Dea MK, Bergman RN. Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo. The Journal of Clinical Investigation. 106: 421-30. PMID 10930445 DOI: 10.1172/JCI7815  0.574
2000 Kjems LL, Christiansen E, Vølund A, Bergman RN, Madsbad S. Validation of methods for measurement of insulin secretion in humans in vivo. Diabetes. 49: 580-8. PMID 10871195 DOI: 10.2337/Diabetes.49.4.580  0.483
2000 Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF. Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes. 49: 399-408. PMID 10868961 DOI: 10.2337/Diabetes.49.3.399  0.538
2000 Watanabe RM, Bergman RN. Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics. Diabetes. 49: 373-82. PMID 10868958 DOI: 10.2337/diabetes.49.3.373  0.555
2000 Woods KA, Camacho-Hübner C, Bergman RN, Barter D, Clark AJ, Savage MO. Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion. The Journal of Clinical Endocrinology and Metabolism. 85: 1407-11. PMID 10770174 DOI: 10.1210/jcem.85.4.6495  0.472
2000 Hevener AL, Bergman RN, Donovan CM. Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes. 49: 8-12. PMID 10615943 DOI: 10.2337/Diabetes.49.1.8  0.441
2000 Watanabe RM, Ghosh S, Langefeld CD, Valle TT, Hauser ER, Magnuson VL, Mohlke KL, Silander K, Ally DS, Chines P, Blaschak-Harvan J, Douglas JA, Duren WL, Epstein MP, Fingerlin TE, ... ... Bergman RN, et al. The Finland–United States Investigation of Non–Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes-Related Quantitative-Trait Loci The American Journal of Human Genetics. 67: 1186-1200. DOI: 10.1016/S0002-9297(07)62949-8  0.469
1999 Richey JM, Ader M, Moore D, Bergman RN. Angiotensin II induces insulin resistance independent of changes in interstitial insulin. The American Journal of Physiology. 277: E920-6. PMID 10567021 DOI: 10.1152/Ajpendo.1999.277.5.E920  0.574
1999 Hamilton-Wessler M, Ader M, Dea M, Moore D, Jorgensen PN, Markussen J, Bergman RN. Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: retention of NN304 by albumin. Diabetologia. 42: 1254-63. PMID 10525669 DOI: 10.1007/s001250051301  0.609
1999 Watanabe RM, Valle T, Hauser ER, Ghosh S, Eriksson J, Kohtamäki K, Ehnholm C, Tuomilehto J, Collins FS, Bergman RN, Boehnke M. Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. Human Heredity. 49: 159-68. PMID 10364681 DOI: 10.1159/000022865  0.532
1999 Carpentier A, Mittelman SD, Lamarche B, Bergman RN, Giacca A, Lewis GF. Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. The American Journal of Physiology. 276: E1055-66. PMID 10362618 DOI: 10.1152/ajpendo.1999.276.6.E1055  0.41
1999 Richey JM, Poulin RA, Buchanan TA, Galperin E, Moore DM, Bergman RN. Failure of acute hyperinsulinemia to alter blood pressure is not due to baroreceptor feedback. American Journal of Hypertension. 12: 405-13. PMID 10232501 DOI: 10.1016/S0895-7061(98)00272-6  0.453
1999 Ghosh S, Langefeld CD, Ally D, Watanabe RM, Hauser ER, Magnuson VL, Nylund SJ, Valle T, Eriksson J, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. Diabetologia. 42: 238-44. PMID 10064105 DOI: 10.1007/S001250051144  0.408
1999 Hamilton-Wessler M, Bergman RN. Early or late elevation of free fatty acids induce equivalent insulin resistance during hyperinsulinemic clamp in dogs Journal of Investigative Medicine. 47.  0.438
1999 Dea MK, Van Citters GW, Ader M, Bergman RN. Troglitazone enhances adipocyte insulin sensitivity without affecting endogenous glucose production in normal dogs Journal of Investigative Medicine. 47: 76A.  0.813
1998 Watanabe RM, Steil GM, Bergman RN. Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 274: E172-E183. PMID 29590976 DOI: 10.1152/ajpendo.1998.274.1.E172  0.322
1998 Bergman RN, Mittelman SD. Central role of the adipocyte in insulin resistance. Journal of Basic and Clinical Physiology and Pharmacology. 9: 205-21. PMID 10212835 DOI: 10.1515/Jbcpp.1998.9.2-4.205  0.645
1998 Getty L, Hamilton-Wessler M, Ader M, Dea MK, Bergman RN. Biphasic insulin secretion during intravenous glucose tolerance test promotes optimal interstitial insulin profile. Diabetes. 47: 1941-7. PMID 9836528 DOI: 10.2337/Diabetes.47.12.1941  0.611
1998 Ader M, Richey JM, Bergman RN. Evidence for direct action of alloxan to induce insulin resistance at the cellular level. Diabetologia. 41: 1327-36. PMID 9833941 DOI: 10.1007/s001250051073  0.592
1998 Howard G, Bergman R, Wagenknecht LE, Haffner SM, Savage PJ, Saad MF, Laws A, D’Agostino RB. Ability Of Alternative Indices Of Insulin Sensitivity To Predict Cardiovascular Risk : Comparison With The Minimal Model Annals of Epidemiology. 8: 358-369. PMID 9708871 DOI: 10.1016/S1047-2797(98)00002-7  0.484
1998 Haffner SM, D'Agostino R, Mykkänen L, Hales CN, Savage PJ, Bergman RN, O'Leary D, Rewers M, Selby J, Tracy R, Saad MF. Proinsulin and insulin concentrations in relation to carotid wall thickness: Insulin Resistance Atherosclerosis Study. Stroke; a Journal of Cerebral Circulation. 29: 1498-503. PMID 9707183 DOI: 10.1161/01.STR.29.8.1498  0.602
1998 Steil GM, Rebrin K, Mittelman SD, Bergman RN. Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity. Diabetes. 47: 714-20. PMID 9588441 DOI: 10.2337/diabetes.47.5.714  0.626
1998 Mayer-Davis EJ, D'Agostino R, Karter AJ, Haffner SM, Rewers MJ, Saad M, Bergman RN. Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study. Jama. 279: 669-74. PMID 9496984 DOI: 10.1001/Jama.279.9.669  0.549
1998 Watanabe RM, Steil GM, Bergman RN. Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion. The American Journal of Physiology. 274: E172-83. PMID 9458763 DOI: 10.1152/Ajpendo.1998.274.1.E172  0.435
1998 Donovan CM, Hevener AL, Bergman RN. The detection of hypoglycemia by portal vein glucosensors Current Opinion in Endocrinology and Diabetes. 5: 256-260. DOI: 10.1097/00060793-199811000-00004  0.406
1998 Mittelman S, Bergman RN. Liver glucose production in health and diabetes Current Opinion in Endocrinology and Diabetes. 5: 126-135. DOI: 10.1097/00060793-199804000-00008  0.583
1997 Mittelman SD, Fu YY, Rebrin K, Steil G, Bergman RN. Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. The Journal of Clinical Investigation. 100: 3121-30. PMID 9399959 DOI: 10.1172/JCI119867  0.626
1997 Saad MF, Steil GM, Riad-Gabriel M, Khan A, Sharma A, Boyadjian R, Jinagouda SD, Bergman RN. Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol. Diabetes. 46: 2044-8. PMID 9392494 DOI: 10.2337/Diab.46.12.2044  0.613
1997 Ni TC, Ader M, Bergman RN. Reassessment of glucose effectiveness and insulin sensitivity from minimal model analysis: a theoretical evaluation of the single-compartment glucose distribution assumption. Diabetes. 46: 1813-21. PMID 9356031 DOI: 10.2337/Diab.46.11.1813  0.502
1997 Hevener AL, Bergman RN, Donovan CM. Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes. 46: 1521-5. PMID 9287058 DOI: 10.2337/Diab.46.9.1521  0.473
1997 Mykkänen L, Haffner SM, Rönnemaa T, Bergman RN, Laakso M. Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. American Journal of Epidemiology. 146: 315-21. PMID 9270410 DOI: 10.1093/Oxfordjournals.Aje.A009272  0.538
1997 Bergman RN. New concepts in extracellular signaling for insulin action: the single gateway hypothesis. Recent Progress in Hormone Research. 52: 359-85; discussion 3. PMID 9238859  0.581
1997 Saad MF, Steil GM, Kades WW, Ayad MF, Elsewafy WA, Boyadjian R, Jinagouda SD, Bergman RN. Differences between the tolbutamide-boosted and the insulin-modified minimal model protocols. Diabetes. 46: 1167-71. PMID 9200652 DOI: 10.2337/Diab.46.7.1167  0.584
1997 Ader M, Ni TC, Bergman RN. Glucose effectiveness assessed under dynamic and steady state conditions. Comparability of uptake versus production components. The Journal of Clinical Investigation. 99: 1187-99. PMID 9077526 DOI: 10.1172/JCI119275  0.523
1997 Hofman PL, Cutfield WS, Robinson EM, Bergman RN, Menon RK, Sperling MA, Gluckman PD. Insulin resistance in short children with intrauterine growth retardation. The Journal of Clinical Endocrinology and Metabolism. 82: 402-6. PMID 9024226 DOI: 10.1210/jcem.82.2.3752  0.598
1997 Mayer-Davis EJ, Monaco JH, Hoen HM, Carmichael S, Vitolins MZ, Rewers MJ, Haffner SM, Ayad MF, Bergman RN, Karter AJ. Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS) The American Journal of Clinical Nutrition. 65: 79-87. PMID 8988917 DOI: 10.1093/Ajcn/65.1.79  0.547
1997 Haffner SM, Howard G, Mayer E, Bergman RN, Savage PJ, Rewers M, Mykkänen L, Karter AJ, Hamman R, Saad MF. Insulin sensitivity and acute insulin response in African-Americans, non-Hispanic whites, and Hispanics with NIDDM: the Insulin Resistance Atherosclerosis Study. Diabetes. 46: 63-9. PMID 8971083 DOI: 10.2337/Diab.46.1.63  0.559
1997 Hevener AL, Bergman RN, Donovan CM. PORTOHEPATIC GLUCOSENSORS ARE CRITICAL FOR GLUCOSE HOMEOSTASIS IN THE RAT 248 Medicine &Amp Science in Sports &Amp Exercise. 29: 43. DOI: 10.1097/00005768-199705001-00248  0.304
1996 Steil GM, Richey J, Kim JK, Wi JK, Rebrin K, Bergman RN, Youn JH. Extracellular glucose distribution is not altered by insulin: analysis of plasma and interstitial L-glucose kinetics. The American Journal of Physiology. 271: E855-64. PMID 8944672 DOI: 10.1152/Ajpendo.1996.271.5.E855  0.569
1996 Bergman RN, Watanabe R, Rebrin K, Ader M, Steil G. Toward an integrated phenotype in pre-NIDDM. Diabetic Medicine : a Journal of the British Diabetic Association. 13: S67-77. PMID 8894486  0.559
1996 Best JD, Kahn SE, Ader M, Watanabe RM, Ni TC, Bergman RN. Role of glucose effectiveness in the determination of glucose tolerance. Diabetes Care. 19: 1018-30. PMID 8875104 DOI: 10.2337/diacare.19.9.1018  0.472
1996 Karter AJ, Mayer-Davis EJ, Selby JV, D'Agostino RB, Haffner SM, Sholinsky P, Bergman R, Saad MF, Hamman RF. Insulin sensitivity and abdominal obesity in African-American, Hispanic, and non-Hispanic white men and women: The insulin resistance and atherosclerosis study Diabetes. 45: 1547-1555. PMID 8866560 DOI: 10.2337/Diab.45.11.1547  0.586
1996 D'Agostino RB, Burke G, O'Leary D, Rewers M, Selby J, Savage PJ, Saad MF, Bergman RN, Howard G, Wagenknecht L, Haffner SM. Ethnic differences in carotid wall thickness. The Insulin Resistance Atherosclerosis Study. Stroke; a Journal of Cerebral Circulation. 27: 1744-9. PMID 8841322 DOI: 10.1161/01.Str.27.10.1744  0.349
1996 Clausen JO, Borch-Johnsen K, Ibsen H, Bergman RN, Hougaard P, Winther K, Pedersen O. Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. The Journal of Clinical Investigation. 98: 1195-209. PMID 8787683 DOI: 10.1172/JCI118903  0.566
1996 Rebrin K, Steil GM, Mittelman SD, Bergman RN. Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. The Journal of Clinical Investigation. 98: 741-9. PMID 8698866 DOI: 10.1172/JCI118846  0.647
1996 Howard G, O'Leary DH, Zaccaro D, Haffner S, Rewers M, Hamman R, Selby JV, Saad MF, Savage P, Bergman R. Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators. Circulation. 93: 1809-17. PMID 8635260 DOI: 10.1161/01.CIR.93.10.1809  0.604
1996 Steil GM, Ader M, Moore DM, Rebrin K, Bergman RN. Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. The Journal of Clinical Investigation. 97: 1497-503. PMID 8617883 DOI: 10.1172/JCI118572  0.592
1996 Ni TC, Ader M, Bergman RN. Reassessment of glucose effectiveness and insulin sensitivity from the Minimal model: Effects of structure simplification Journal of Investigative Medicine. 44.  0.422
1996 Watanabe RM, Azen CG, Roy S, Bergman RN. Reduced hepatic insulin extraction accounts for increased insulin concentrations observed in long-term users of oral contraceptives Journal of Investigative Medicine. 44.  0.373
1996 Mittelman SD, Rebrin K, Steil GM, Bergman RN. Prevention of insulin suppression of HGO by intralipid is due to free fatty acids, not glycerol Journal of Investigative Medicine. 44.  0.505
1995 Wagenknecht LE, Mayer EJ, Rewers M, Haffner S, Selby J, Borok GM, Henkin L, Howard G, Savage PJ, Saad MF, Bergman RN, Hamman R. The insulin resistance atherosclerosis study (IRAS) objectives, design, and recruitment results. Annals of Epidemiology. 5: 464-472. PMID 8680609 DOI: 10.1016/1047-2797(95)00062-3  0.582
1995 Bradley DC, Steil GM, Bergman RN. OOPSEG: a data smoothing program for quantitation and isolation of random measurement error. Computer Methods and Programs in Biomedicine. 46: 67-77. PMID 7743783 DOI: 10.1016/0169-2607(94)01600-K  0.43
1995 Rebrin K, Steil GM, Getty L, Bergman RN. Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes. 44: 1038-45. PMID 7657026 DOI: 10.2337/Diab.44.9.1038  0.628
1995 Watanabe RM, Lovejoy J, Steil GM, DiGirolamo M, Bergman RN. Insulin sensitivity accounts for glucose and lactate kinetics after intravenous glucose injection. Diabetes. 44: 954-62. PMID 7622002 DOI: 10.2337/diab.44.8.954  0.564
1994 Yang YJ, Hope ID, Ader M, Bergman RN. Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose. The American Journal of Physiology. 266: E17-25. PMID 8304440 DOI: 10.1152/Ajpendo.1994.266.1.E17  0.619
1994 Kemnitz JW, Elson DF, Roecker EB, Baum ST, Bergman RN, Meglasson MD. Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. Diabetes. 43: 204-11. PMID 8288044 DOI: 10.2337/Diab.43.2.204  0.598
1994 Poulin RA, Steil GM, Moore DM, Ader M, Bergman RN. Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph. Diabetes. 43: 180-90. PMID 8288041 DOI: 10.2337/Diab.43.2.180  0.618
1994 Castillo C, Bogardus C, Bergman R, Thuillez P, Lillioja S. Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men. Journal of Clinical Investigation. 93: 10-16. PMID 8282776 DOI: 10.1172/Jci116932  0.635
1994 Kemnitz JW, Roecker EB, Weindruch R, Elson DF, Baum ST, Bergman RN. Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. The American Journal of Physiology. 266: E540-7. PMID 8178974 DOI: 10.1152/Ajpendo.1994.266.4.E540  0.628
1994 Mykkänen L, Haffner SM, Rönnemaa T, Bergman R, Leino A, Laakso M. Is there a sex difference in the association of plasma insulin level and insulin sensitivity with serum lipids and lipoproteins? Metabolism: Clinical and Experimental. 43: 523-8. PMID 8159115 DOI: 10.1016/0026-0495(94)90088-4  0.475
1994 Donovan CM, Hamilton-Wessler M, Halter JB, Bergman RN. Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia. Proceedings of the National Academy of Sciences of the United States of America. 91: 2863-7. PMID 8146201 DOI: 10.1073/Pnas.91.7.2863  0.395
1994 Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP. The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects. Diabetes. 43: 587-92. PMID 8138065  0.544
1994 Wing RR, Blair EH, Bononi P, Marcus MD, Watanabe R, Bergman RN. Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes Care. 17: 30-6. PMID 8112186 DOI: 10.2337/Diacare.17.1.30  0.584
1994 Saad MF, Anderson RL, Laws A, Watanabe RM, Kades WW, Chen YD, Sands RE, Pei D, Savage PJ, Bergman RN. A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Insulin Resistance Atherosclerosis Study. Diabetes. 43: 1114-21. PMID 8070611 DOI: 10.2337/diab.43.9.1114  0.52
1994 Mykkanen L, Ronnemaa T, Marniemi J, Haffner SM, Bergman R, Laakso M. Insulin sensitivity is not an independent determinant of plasma plasminogen activator inhibitor-1 activity. Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 1264-1271. PMID 8049187 DOI: 10.1161/01.Atv.14.8.1264  0.578
1994 Watanabe RM, Azen CG, Roy S, Perlman JA, Bergman RN. Defects in carbohydrate metabolism in oral contraceptive users without apparent metabolic risk factors. The Journal of Clinical Endocrinology and Metabolism. 79: 1277-83. PMID 7962320 DOI: 10.1210/jcem.79.5.7962320  0.527
1994 Steil GM, Murray J, Bergman RN, Buchanan TA. Repeatability of insulin sensitivity and glucose effectiveness from the minimal model. Implications for study design. Diabetes. 43: 1365-71. PMID 7926313 DOI: 10.2337/Diab.43.11.1365  0.522
1994 Bergman RN, Steil G, Ader M, Poulin R, Bradley DC. Measurement in Lymph: Metabolic Insights from Sampling the Remote Compartment Ifac Proceedings Volumes. 27: 313-317. DOI: 10.1016/S1474-6670(17)46252-5  0.437
1994 Watanabe RM, Steil GM, Bergman RN, Kruszynska Y. The Combined Model Approach for Assessment of in Vivo Insulin Secretion Rates Ifac Proceedings Volumes. 27: 307-308. DOI: 10.1016/S1474-6670(17)46249-5  0.515
1993 Nadler JL, Buchanan T, Natarajan R, Antonipillai I, Bergman R, Rude R. Magnesium deficiency produces insulin resistance and increased thromboxane synthesis. Hypertension (Dallas, Tex. : 1979). 21: 1024-9. PMID 8505087 DOI: 10.1161/01.Hyp.21.6.1024  0.564
1993 Steil GM, Meador MA, Bergman RN. Thoracic duct lymph. Relative contribution from splanchnic and muscle tissue. Diabetes. 42: 720-31. PMID 8482429 DOI: 10.2337/Diab.42.5.720  0.363
1993 Kruszynska YT, Harry DS, Bergman RN, McIntyre N. Insulin sensitivity, insulin secretion and glucose effectiveness in diabetic and non-diabetic cirrhotic patients. Diabetologia. 36: 121-8. PMID 8458526 DOI: 10.1007/BF00400692  0.579
1993 Morrow LA, Morganroth GS, Herman WH, Bergman RN, Halter JB. Effects of epinephrine on insulin secretion and action in humans. Interaction with aging. Diabetes. 42: 307-15. PMID 8425666 DOI: 10.2337/Diab.42.2.307  0.508
1993 Steil GM, Volund A, Kahn SE, Bergman RN. Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes. 42: 250-6. PMID 8425661 DOI: 10.2337/Diab.42.2.250  0.423
1993 Baura GD, Foster DM, Porte D, Kahn SE, Bergman RN, Cobelli C, Schwartz MW. Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. The Journal of Clinical Investigation. 92: 1824-30. PMID 8408635 DOI: 10.1172/Jci116773  0.567
1993 Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes. 42: 1663-72. PMID 8405710 DOI: 10.2337/Diab.42.11.1663  0.501
1993 Buyalos RP, Geffner ME, Watanabe RM, Bergman RN, Gornbein JA, Judd HL. The influence of luteinizing hormone and insulin on sex steroids and sex hormone-binding globulin in the polycystic ovarian syndrome. Fertility and Sterility. 60: 626-33. PMID 8405515 DOI: 10.1016/S0015-0282(16)56212-8  0.572
1993 Bradley DC, Steil GM, Bergman RN. Quantitation of measurement error with Optimal Segments: basis for adaptive time course smoothing. The American Journal of Physiology. 264: E902-11. PMID 8333516 DOI: 10.1152/Ajpendo.1993.264.6.E902  0.425
1993 Bergman RN, Bradley DC, Ader M. On insulin action in vivo: the single gateway hypothesis. Advances in Experimental Medicine and Biology. 334: 181-98. PMID 8249682 DOI: 10.1007/978-1-4615-2910-1_13  0.69
1993 Bradley DC, Poulin RA, Bergman RN. Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo. Diabetes. 42: 296-306. PMID 8093879 DOI: 10.2337/Diab.42.2.296  0.733
1992 Yang YJ, Hope I, Ader M, Poulin RA, Bergman RN. Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues. Diabetes. 41: 241-53. PMID 1733816  0.539
1992 Lee A, Ader M, Bray GA, Bergman RN. Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects. Diabetes. 41: 750-9. PMID 1587401 DOI: 10.2337/Diab.41.6.750  0.581
1992 Haffner SM, Stern MP, Watanabe RM, Bergman RN. Relationship of insulin clearance and secretion to insulin sensitivity in non-diabetic Mexican Americans. European Journal of Clinical Investigation. 22: 147-53. PMID 1582438 DOI: 10.1111/j.1365-2362.1992.tb01819.x  0.618
1992 Bradley DC, Bergman RN. Hepatic glucagon sensitivity and fasting glucose concentration in normal dogs. The American Journal of Physiology. 262: E539-45. PMID 1566839 DOI: 10.1152/Ajpendo.1992.262.4.E539  0.694
1992 Kahn SE, Bergman RN, Schwartz MW, Taborsky GJ, Porte D. Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans. The American Journal of Physiology. 262: E518-23. PMID 1566838 DOI: 10.1152/Ajpendo.1992.262.4.E518  0.635
1992 Bergman RN, Steil GM, Bradley DC, Watanabe RM. Modeling of insulin action in vivo. Annual Review of Physiology. 54: 861-83. PMID 1562195 DOI: 10.1146/annurev.ph.54.030192.004241  0.639
1992 Buyalos RP, Geffner ME, Bersch N, Judd HL, Watanabe RM, Bergman RN, Golde DW. Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome. Fertility and Sterility. 57: 796-803. PMID 1555690 DOI: 10.1016/S0015-0282(16)54961-9  0.578
1992 Supiano MA, Hogikyan RV, Morrow LA, Ortiz-Alonso FJ, Herman WH, Bergman RN, Halter JB. Hypertension and insulin resistance: role of sympathetic nervous system activity. The American Journal of Physiology. 263: E935-42. PMID 1443127 DOI: 10.1152/Ajpendo.1992.263.5.E935  0.529
1992 Martin BC, Warram JH, Krolewski AS, Bergman RN, Soeldner JS, Kahn CR. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet (London, England). 340: 925-9. PMID 1357346 DOI: 10.1016/0140-6736(92)92814-V  0.589
1992 Pacini G, Ader M, Bergman RN. BASREP: a method for maintaining euglycemia during somatostatin suppression of pancreatic secretion. Computer Methods and Programs in Biomedicine. 37: 107-15. PMID 1353714 DOI: 10.1016/0169-2607(92)90092-L  0.549
1992 Bradley DC, Bergman RN. Restoration of stable metabolic conditions during islet suppression in dogs. The American Journal of Physiology. 262: E532-8. PMID 1348903 DOI: 10.1152/Ajpendo.1992.262.4.E532  0.671
1992 Lee A, Ader M, Bray GA, Bergman RN. Diurnal variation in glucose tolerance: Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects Diabetes. 41: 750-759.  0.485
1991 Swinburn BA, Boyce VL, Bergman RN, Howard BV, Bogardus C. Deterioration in carbohydrate metabolism and lipoprotein changes induced by modern, high fat diet in Pima Indians and Caucasians. The Journal of Clinical Endocrinology and Metabolism. 73: 156-65. PMID 2045466 DOI: 10.1210/jcem-73-1-156  0.532
1991 Youn JH, Bergman RN. Conversion of oral glucose to lactate in dogs. Primary site and relative contribution to blood lactate. Diabetes. 40: 738-47. PMID 2040389 DOI: 10.2337/Diab.40.6.738  0.433
1991 Byerley LO, Heber D, Bergman RN, Dubria M, Chi J. Insulin action and metabolism in patients with head and neck cancer. Cancer. 67: 2900-6. PMID 2025856 DOI: 10.1002/1097-0142(19910601)67:11<2900::Aid-Cncr2820671132>3.0.Co;2-Z  0.613
1991 Schwartz MW, Bergman RN, Kahn SE, Taborsky GJ, Fisher LD, Sipols AJ, Woods SC, Steil GM, Porte D. Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. The Journal of Clinical Investigation. 88: 1272-81. PMID 1918377 DOI: 10.1172/Jci115431  0.504
1991 Buchanan TA, Sipos GF, Gadalah S, Yip KP, Marsh DJ, Hsueh W, Bergman RN. Glucose tolerance and insulin action in rats with renovascular hypertension. Hypertension. 18: 341-7. PMID 1889847 DOI: 10.1161/01.Hyp.18.3.341  0.56
1991 Donovan CM, Halter JB, Bergman RN. Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes. 40: 155-8. PMID 1849847 DOI: 10.2337/Diab.40.1.155  0.513
1991 Watanabe RM, Vølund A, Bergman RN. Intravenous insulin infusion to simulate subcutaneous absorption. Bioavailability and metabolic sequelae. Diabetes Care. 14: 1021-30. PMID 1797482 DOI: 10.2337/diacare.14.11.1021  0.598
1991 Donovan CM, Cane P, Bergman RN. Search for the hypoglycemia receptor using the local irrigation approach. Advances in Experimental Medicine and Biology. 291: 185-96. PMID 1656712 DOI: 10.1007/978-1-4684-5931-9_14  0.409
1991 Kruszynska Y, Bergman R, Mcintyre N. Insulin resistance but normal enhancement of glucose utilisation by hyperglycaemia in cirrhosis -“minimal model” analysis Journal of Hepatology. 13. DOI: 10.1016/0168-8278(91)91518-L  0.616
1990 Bergman RN, Yang YJ, Hope ID, Ader M. The role of the transcapillary insulin transport in the efficiency of insulin action: studies with glucose clamps and the minimal model. Hormone and Metabolic Research. Supplement Series. 24: 49-56. PMID 2272626  0.557
1990 Welch S, Gebhart SS, Bergman RN, Phillips LS. Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. The Journal of Clinical Endocrinology and Metabolism. 71: 1508-18. PMID 2229309 DOI: 10.1210/jcem-71-6-1508  0.615
1990 Selam JL, Bergman RN, Raccah D, Jean-Didier N, Lozano J, Charles MA. Determination of portal insulin absorption from peritoneum via novel nonisotopic method. Diabetes. 39: 1361-5. PMID 2227110 DOI: 10.2337/Diab.39.11.1361  0.606
1990 Kahn SE, Klaff LJ, Schwartz MW, Beard JC, Bergman RN, Taborsky GJ, Porte D. Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose. The Journal of Clinical Endocrinology and Metabolism. 71: 994-1002. PMID 2205630 DOI: 10.1210/Jcem-71-4-994  0.511
1990 Schwartz MW, Sipols A, Kahn SE, Lattemann DF, Taborsky GJ, Bergman RN, Woods SC, Porte D. Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. The American Journal of Physiology. 259: E378-83. PMID 2205107 DOI: 10.1152/Ajpendo.1990.259.3.E378  0.591
1990 Haffner SM, Stern MP, Dunn J, Mobley M, Blackwell J, Bergman RN. Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic Mexican Americans. Metabolism: Clinical and Experimental. 39: 842-7. PMID 2198435 DOI: 10.1016/0026-0495(90)90130-5  0.606
1990 Youn JH, Bergman RN. Enhancement of hepatic glycogen by gluconeogenic precursors: substrate flux or metabolic control? The American Journal of Physiology. 258: E899-906. PMID 2193531 DOI: 10.1152/Ajpendo.1990.258.6.E899  0.449
1990 Ader M, Bergman RN. Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. The American Journal of Physiology. 258: E1020-32. PMID 2193527 DOI: 10.1152/Ajpendo.1990.258.6.E1020  0.627
1990 Cutfield WS, Bergman RN, Menon RK, Sperling MA. The modified minimal model: application to measurement of insulin sensitivity in children. The Journal of Clinical Endocrinology and Metabolism. 70: 1644-50. PMID 2189887 DOI: 10.1210/jcem-70-6-1644  0.5
1990 Buchanan TA, Metzger BE, Freinkel N, Bergman RN. Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes. American Journal of Obstetrics and Gynecology. 162: 1008-14. PMID 2183610 DOI: 10.1016/0002-9378(90)91306-W  0.517
1989 Bergman RN. Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes. 38: 1512-27. PMID 2684710 DOI: 10.2337/Diab.38.12.1512  0.634
1989 Yang YJ, Hope ID, Ader M, Bergman RN. Insulin transport across capillaries is rate limiting for insulin action in dogs. The Journal of Clinical Investigation. 84: 1620-8. PMID 2681272 DOI: 10.1172/JCI114339  0.611
1989 Watanabe RM, Volund A, Roy S, Bergman RN. Prehepatic beta-cell secretion during the intravenous glucose tolerance test in humans: application of a combined model of insulin and C-peptide kinetics. The Journal of Clinical Endocrinology and Metabolism. 69: 790-7. PMID 2674187 DOI: 10.1210/jcem-69-4-790  0.561
1989 Bergman RN, Hope ID, Yang YJ, Watanabe RM, Meador MA, Youn JH, Ader M. Assessment of insulin sensitivity in vivo: a critical review. Diabetes/Metabolism Reviews. 5: 411-29. PMID 2667927 DOI: 10.1002/dmr.5610050501  0.521
1989 Kahn SE, Beard JC, Schwartz MW, Ward WK, Ding HL, Bergman RN, Taborsky GJ, Porte D. Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes. 38: 562-8. PMID 2653928 DOI: 10.2337/Diab.38.5.562  0.604
1989 Bergman RN, Buchanan TA. Impact of computer simulation on diabetes research and practice. Diabetes Care. 12: 748-9. PMID 2612309 DOI: 10.2337/Diacare.12.10.748  0.405
1988 Finegood DT, Bergman RN, Vranic M. Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes. 37: 1025-34. PMID 3292323 DOI: 10.2337/Diab.37.8.1025  0.453
1988 Chen M, Bergman RN, Porte D. Insulin resistance and beta-cell dysfunction in aging: the importance of dietary carbohydrate. The Journal of Clinical Endocrinology and Metabolism. 67: 951-7. PMID 3053750 DOI: 10.1210/jcem-67-5-951  0.396
1988 McCulloch DK, Raghu PK, Johnston C, Klaff LJ, Kahn SE, Beard JC, Ward WK, Benson EA, Koerker DJ, Bergman RN. Defects in beta-cell function and insulin sensitivity in normoglycemic streptozocin-treated baboons: a model of preclinical insulin-dependent diabetes. The Journal of Clinical Endocrinology and Metabolism. 67: 785-92. PMID 3047163 DOI: 10.1210/jcem-67-4-785  0.547
1988 Cane P, Haun CK, Evered J, Youn JH, Bergman RN. Response to deep hypoglycemia does not involve glucoreceptors in carotid perfused tissue. The American Journal of Physiology. 255: E680-7. PMID 2847539 DOI: 10.1152/Ajpendo.1988.255.5.E680  0.443
1987 Youn JH, Bergman RN. Patterns of glycogen turnover in liver characterized by computer modeling American Journal of Physiology - Endocrinology and Metabolism. 253. PMID 3661699 DOI: 10.1152/Ajpendo.1987.253.4.E360  0.304
1987 Johnston C, Raghu P, McCulloch DK, Beard JC, Ward WK, Klaff LJ, McKnight B, Bergman RN, Palmer JP. β-cell function and insulin sensitivity in nondiabetic HLA-identical siblings of insulin-dependent diabetics Diabetes. 36: 829-837. PMID 3556281 DOI: 10.2337/Diab.36.7.829  0.623
1987 Bergman RN, Prager R, Volund A, Olefsky JM. Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp Journal of Clinical Investigation. 79: 790-800. PMID 3546379 DOI: 10.1172/Jci112886  0.619
1987 Ader M, Agajanian T, Finegood DT, Bergman RN. Recombinant deoxyribonucleic acid-derived 22K- and 20K-human growth hormone generate equivalent diabetogenic effects during chronic infusion in dogs Endocrinology. 120: 725-731. PMID 3542508 DOI: 10.1210/Endo-120-2-725  0.557
1987 Ader M, Bergman RN. 6 Insulin sensitivity in the intact organism Bailliere's Clinical Endocrinology and Metabolism. 1: 879-910. PMID 3330434 DOI: 10.1016/S0950-351X(87)80010-1  0.627
1987 Finegood DT, Bergman RN, Vranic M. Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates Diabetes. 36: 914-924. PMID 3297886 DOI: 10.2337/Diab.36.8.914  0.502
1987 Yang YJ, Youn JH, Bergman RN. Modified protocols improve insulin sensitivity estimation using the minimal model American Journal of Physiology - Endocrinology and Metabolism. 253. PMID 2892414 DOI: 10.1152/Ajpendo.1987.253.6.E595  0.598
1987 Volund A, Polonsky KS, Bergman RN. Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics Diabetes. 36: 1195-1202. PMID 2888696 DOI: 10.2337/Diab.36.10.1195  0.465
1986 Pacini G, Bergman RN. MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test Computer Methods and Programs in Biomedicine. 23: 113-122. PMID 3640682 DOI: 10.1016/0169-2607(86)90106-9  0.572
1986 Marsh BD, Marsh DJ, Bergman RN. Oscillations enhance the efficiency and stability of glucose disposal. The American Journal of Physiology. 250: E576-82. PMID 3518489 DOI: 10.1152/Ajpendo.1986.250.5.E576  0.55
1986 Beard JC, Bergman RN, Ward WK, Porte D. The insulin sensitivity index in nondiabetic man. Correlation between clamp-derived and IVGTT-derived values. Diabetes. 35: 362-9. PMID 3512346 DOI: 10.2337/Diab.35.3.362  0.441
1986 Youn JH, Youn MS, Bergman RN. Synergism of glucose and fructose in net glycogen synthesis in perfused rat livers Journal of Biological Chemistry. 261: 15960-15969. PMID 3023336  0.38
1986 Cane P, Artal R, Bergman RN. Putative hypothalamic glucoreceptors play no essential role in the response to moderate hypoglycemia Diabetes. 35: 268-277. PMID 3005093 DOI: 10.2337/Diab.35.3.268  0.466
1985 Raghu P, Johnston C, Beard JC, Bergman R, McCulloch DK, Palmer JP. Reduced insulin sensitivity in nondiabetic, HLA-identical siblings of insulin-dependent diabetic subjects Diabetes. 34: 991-994. PMID 4043555 DOI: 10.2337/Diab.34.10.991  0.577
1985 Dimitriadis G, Baker B, Marsh H, Mandarino L, Rizza R, Bergman R, Haymond M, Gerich J. Effect of thyroid hormone excess on action, secretion, and metabolism of insulin in humans The American Journal of Physiology. 248. PMID 3887944 DOI: 10.1152/Ajpendo.1985.248.5.E593  0.61
1985 Bergman RN, Finegood DT, Ader M. Assessment of insulin sensitivity in vivo. Endocrine Reviews. 6: 45-86. PMID 3884329 DOI: 10.1210/Edrv-6-1-45  0.513
1985 Chen M, Bergman RN, Pacini G, Porte D. Pathogenesis of age-related glucose intolerance in man: Insulin resistance and decreased β-cell function Journal of Clinical Endocrinology and Metabolism. 60: 13-20. PMID 3880560 DOI: 10.1210/Jcem-60-1-13  0.613
1985 Geffner ME, Kaplan SA, Bersch N, Lippe BM, Scott ML, Bergman RN, Golde DW. Diminished in vitro responsiveness of circulating erythroid progenitor cells to insulin as an indicator of insulin resistance. The Journal of Clinical Endocrinology and Metabolism. 60: 103-8. PMID 3880558 DOI: 10.1210/jcem-60-1-103  0.626
1985 Ader M, Pacini G, Yang YJ, Bergman RN. Importance of glucose per se to intravenous glucose tolerance: Comparison of the minimal-model prediction with direct measurements Diabetes. 34: 1092-1103. PMID 2864297 DOI: 10.2337/Diab.34.11.1092  0.579
1984 Finegood DT, Pacini G, Bergman RN. The insulin sensitivity index. Correlation in dogs between values determined from the intravenous glucose tolerance test and the euglycemic glucose clamp Diabetes. 33: 362-368. PMID 6368293 DOI: 10.2337/Diab.33.4.362  0.597
1984 Bergman RN, Ader M, Finegood DT, Pacini G. Extrapancreatic effect of somatostatin infusion to increase glucose clearance The American Journal of Physiology. 247. PMID 6148014 DOI: 10.1152/Ajpendo.1984.247.3.E370  0.57
1984 Ader M, Bergman RN. Do basal levels of growth hormone regulate insulin sensitivity? Federation Proceedings. 43.  0.393
1984 Cane P, Bergman RN. The role of the central nervous system in the systemic response to insulin-induced hypoglycemia Federation Proceedings. 43.  0.415
1983 Pacini G, Bergman RN. PACBERG: An adaptive program for controlling the blood sugar Computer Programs in Biomedicine. 16: 13-20. PMID 6342930 DOI: 10.1016/0010-468X(83)90003-X  0.543
1983 Cobelli C, Mari A, Thomaseth K, Bergman RN. SIMPLE VS COMPREHENSIVE MODELS OF GLUCOSE/INSULIN DYNAMIC INTERACTIONS IN THE WHOLE ORGANISM. ROLE OF IDENTIFICATION AND VALIDATION . 2: 1021-1026. DOI: 10.1016/S1474-6670(17)63129-X  0.448
1982 Bergman RN, Beir JR, Hourigan PM. Intraportal glucose infusion matched to oral glucose absorption. Lack of evidence for 'gut factor' involvement in hepatic glucose storage Diabetes. 31: 27-35. PMID 7152123 DOI: 10.2337/Diab.31.1.27  0.498
1982 Pacini G, Finegood DT, Bergman RN. A minimal-model-based glucose clamp yielding insulin sensitivity independent of glycemia Diabetes. 31: 432-441. PMID 6759258 DOI: 10.2337/Diab.31.5.432  0.599
1982 Bergman RN, Finegood DT. Insulin resistance and beta-cell hyper-responsivity with growth hormone: Conservation of glucose tolerance Diabetes. 31.  0.453
1982 Pacini G, Bergman RN. Importance of dynamic insulin response and basal insulin to glucose disappearance following glucose injection Federation Proceedings. 41: 4105.  0.522
1981 Bergman RN, Phillips LS, Cobelli C. Physiologic evaluation of factors controlling glucose tolerance in man. Measurement of insulin sensitivity and β-cell glucose sensitivity from the response to intravenous glucose Journal of Clinical Investigation. 68: 1456-1467. PMID 7033284 DOI: 10.1172/Jci110398  0.611
1981 Bergman RN, Cobellit C, Toffolo G. Minimal models of glucose/insulin dynamics in the intact organism: A novel approach for evaluation of factors controlling glucose tolerance Transactions of the Institute of Measurement &Amp; Control. 3: 207-216. DOI: 10.1177/014233128100300404  0.49
1980 Toffolo G, Bergman RN, Finegood DT, Bowden CR, Cobelli C. Quantitative estimation of beta cell sensitivity to glucose in the intact organism. A minimal model of insulin kinetics in the dog Diabetes. 29: 979-990. PMID 7002673 DOI: 10.2337/Diab.29.12.979  0.617
1980 Bowden CR, Bergman RN, Marsh DJ. Cause of glucose oscillations during glucose infusion: periodic variation in glucose uptake The American Journal of Physiology. 238. PMID 6990778 DOI: 10.1152/Ajpendo.1980.238.4.E395  0.541
1980 Taborsky GJ, Bergman RN. Effect of insulin, glucose, and 2-deoxy-glucose infusion into the third cerebral ventricle of conscious dogs on plasma insulin, glucose, and free fatty acids Diabetes. 29: 278-283. PMID 6987116 DOI: 10.2337/Diab.29.4.278  0.63
1980 Bergman RN, Cobelli C. Minimal modeling, partition analysis, and the estimation of insulin sensitivity Federation Proceedings. 39: 110-115. PMID 6985867  0.419
1979 Bowden CR, Bergman RN. Caval occlusion technique for hepatic venous sampling: A new approach to estimating splanchnic substrate balance in conscious dogs Metabolism. 28: 562-567. PMID 449697 DOI: 10.1016/0026-0495(79)90198-7  0.306
1979 Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity. The American Journal of Physiology. 236: E667-77. PMID 443421 DOI: 10.1152/Ajpendo.1979.236.6.E667  0.577
1979 El-Refai M, Bergman RN. Glucagon-stimulated glycogenolysis: Time-dependent sensitivity to insulin American Journal of Physiology Endocrinology Metabolism and Gastrointestinal Physiology. 5. DOI: 10.1152/Ajpendo.1979.236.3.E246  0.574
1979 Ider YZ, Bergman RN. Evanescence of glucagon-stimulated glucose productions: Importance of diminishing glycogen and hyperglycemia Federation Proceedings. 38.  0.324
1979 Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity American Journal of Physiology Endocrinology Metabolism and Gastrointestinal Physiology. 5.  0.495
1978 Bergman RN, Ider YZ. Quantitative estimation of peripheral insulin sensitivity Diabetes. 27: 151.  0.432
1978 Ider YZ, Bergman RN. A minimal model for plasma glucose disappearance Federation Proceedings. 37.  0.308
1978 Bowden CR, Marsh DJ, Bergman RN. Source of glucose oscillations induced by constant glucose infusion Federation Proceedings. 37.  0.351
1977 Bergman RN. Integrated control of hepatic glucose metabolism Federation Proceedings. 36: 265-270. PMID 190047  0.434
1977 Bergman RN. Dynamic integration of the pancreatic signals controlling hepatic glucose metabolism Excerpta Medica, Amsterdam, Ics. 256-260.  0.337
1976 El Refal M, Bergman RN. Simulation study of control of hepatic glycogen synthesis by glucose and insulin American Journal of Physiology. 231. PMID 187069 DOI: 10.1152/Ajplegacy.1976.231.5.1608  0.572
1976 Bergman RN, Kalaba RE, Spingarn K. Optimizing inputs for diagnosis of diabetes. I. Fitting a minimal model to data Journal of Optimization Theory and Applications. 20: 47-63. DOI: 10.1007/BF00933347  0.404
1975 Bergman RN, Refai ME. Dynamic control of hepatic glucose metabolism: Studies by experiment and computer simulation Annals of Biomedical Engineering. 3: 411-432. PMID 176905 DOI: 10.1007/BF02409326  0.517
1975 Bergman RN, El Refai M. MODELING STUDIES OF THE DYNAMIC CONTROL OF HEPATIC GLUCOSE BALANCE Journal of Dynamic Systems, Measurement and Control, Transactions of the Asme. 97: 266-275. DOI: 10.1115/1.3426930  0.46
1974 Bucolo RJ, Bergman RN, Marsh DJ, Yates FE. Dynamics of glucose autoregulation in the isolated, blood perfused canine liver American Journal of Physiology. 227: 209-217. PMID 4843372 DOI: 10.1152/Ajplegacy.1974.227.1.209  0.511
1974 Ookhtens M, Marsh DJ, Smith SW, Bergman RN, Yates FE. Fluctuations of plasma glucose and insulin in conscious dogs receiving glucose infusions. The American Journal of Physiology. 226: 910-9. PMID 4823053 DOI: 10.1152/ajplegacy.1974.226.4.910  0.572
1974 Bergman RN, Azen SP. Measurement error inherent in the determination of hepatic glucose balance Journal of Applied Physiology. 36: 269-273. PMID 4811391 DOI: 10.1152/Jappl.1974.36.2.269  0.3
1974 Bergman RN, Bucolo RJ. Interaction of insulin and glucose in the control of hepatic glucose balance The American Journal of Physiology. 227: 1314-1322. PMID 4440776 DOI: 10.1152/Ajplegacy.1974.227.6.1314  0.564
1974 Bucolo RJ, Bergman RN. Simulation of the dynamic effects of glucose and insulin on hepatic glucose balance Federation Proceedings. 33.  0.467
1973 Bergman RN, Miller RE. Direct enhancement of insulin secretion by vagal stimulation of the isolated pancreas American Journal of Physiology. 225: 481-486. PMID 4722412 DOI: 10.1152/Ajplegacy.1973.225.2.481  0.558
1973 Bergman RN, Bucolo RJ. Nonlinear Dynamic Properties of the Pancreas and Liver Ifac Proceedings Volumes. 6: 503-508. DOI: 10.1016/S1474-6670(17)68076-5  0.33
1973 Bergman RN, Bucolo RJ. NONLINEAR METABOLIC DYNAMICS OF THE PANCREAS AND LIVER Journal of Dynamic Systems, Measurement and Control, Transactions of the Asme. 95: 296-300.  0.404
1973 Bergman RN, Bucolo R, Yates FE. Quantitative contribution of glucose in the determination of net hepatic glucose balance Federation Proceedings. 32: 1208.  0.333
1971 Bergman RN, Urquhart J. The pilot gland approach to the study of insulin secretory dynamics Recent Progress in Hormone Research. 27: 583-605 passim. PMID 4946134 DOI: 10.1016/B978-0-12-571127-2.50039-0  0.6
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