Yuk-Ching Tse-Dinh - Publications

Affiliations: 
1988-2012 Biochemistry and Molecular Biology New York Medical College, New York, NY, United States 
 2012- Department of Chemistry & Biochemistry Florida International University, Miami, FL, United States 
Area:
Biochemistry, Molecular Biology, Genetics

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mamun Y, Tse-Dinh YC, Chapagain P. Insights into the DNA and RNA Interactions of Human Topoisomerase III Beta Using Molecular Dynamics Simulations. Journal of Chemical Information and Modeling. PMID 39024468 DOI: 10.1021/acs.jcim.4c00472  0.349
2024 Tan K, Tse-Dinh YC. Variation of Structure and Cellular Functions of Type IA Topoisomerases across the Tree of Life. Cells. 13. PMID 38534397 DOI: 10.3390/cells13060553  0.367
2022 Ferdous S, Dasgupta T, Annamalai T, Tan K, Tse-Dinh YC. The interaction between transport-segment DNA and topoisomerase IA-crystal structure of MtbTOP1 in complex with both G- and T-segments. Nucleic Acids Research. PMID 36583363 DOI: 10.1093/nar/gkac1205  0.367
2022 Alfonso EE, Troche R, Deng Z, Annamalai T, Chapagain P, Tse-Dinh YC, Leng F. Potent Inhibition of Bacterial DNA Gyrase by Digallic Acid and Other Gallate Derivatives. Chemmedchem. e202200301. PMID 36161274 DOI: 10.1002/cmdc.202200301  0.471
2022 Diaz B, Mederos C, Tan K, Tse-Dinh YC. Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and Combination. International Journal of Molecular Sciences. 23. PMID 35955842 DOI: 10.3390/ijms23158709  0.346
2022 Seddek A, Madeira C, Annamalai T, Mederos C, Tiwari PB, Welch AZ, Tse-Dinh YC. A Yeast-Based Screening System for Differential Identification of Poisons and Suppressors of Human Topoisomerase I. Frontiers in Bioscience (Landmark Edition). 27: 93. PMID 35345325 DOI: 10.31083/j.fbl2703093  0.395
2021 Tiwari PB, Chapagain PP, Seddek A, Annamalai T, Üren A, Tse-Dinh YC. Corrigendum: Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development. Chemmedchem. PMID 34145777 DOI: 10.1002/cmdc.202100427  0.379
2021 Huang SN, Michaels SA, Mitchell BB, Majdalani N, Vanden Broeck A, Canela A, Tse-Dinh YC, Lamour V, Pommier Y. Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes. Science Advances. 7. PMID 33658195 DOI: 10.1126/sciadv.abe0384  0.443
2021 Seddek A, Annamalai T, Tse-Dinh YC. Type IA Topoisomerases as Targets for Infectious Disease Treatments. Microorganisms. 9. PMID 33401386 DOI: 10.3390/microorganisms9010086  0.432
2020 Saha S, Sun Y, Huang SN, Baechler SA, Pongor LS, Agama K, Jo U, Zhang H, Tse-Dinh YC, Pommier Y. DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks. Cell Reports. 33: 108569. PMID 33378676 DOI: 10.1016/j.celrep.2020.108569  0.394
2020 Dasgupta T, Ferdous S, Tse-Dinh YC. Mechanism of Type IA Topoisomerases. Molecules (Basel, Switzerland). 25. PMID 33080770 DOI: 10.3390/molecules25204769  0.33
2020 Cao N, Tan K, Zuo X, Annamalai T, Tse-Dinh YC. Mechanistic insights from structure of Mycobacterium smegmatis topoisomerase I with ssDNA bound to both N- and C-terminal domains. Nucleic Acids Research. PMID 32232337 DOI: 10.1093/Nar/Gkaa201  0.431
2020 Tiwari P, Chapagain PP, Seddek A, Annamalai T, Üren A, Tse-Dinh YC. Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development. Chemmedchem. PMID 32043806 DOI: 10.1002/Cmdc.201900721  0.42
2020 Dasgupta T, Tan K, Tse-Dinh Y. Inter‐domain Protein‐Protein Interaction through a Unique α‐Helix in the Hinge Region of E coli Topoisomerase I Leads to the Conformational Change of the Enzyme The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00552  0.353
2020 Tiwari P, Tse-Dinh Y, Üren A. Targeting Covalent Complex of Human Topoisomerase I with DNA Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1712  0.463
2019 Vasquez JL, Lai Y, Annamalai T, Jiang Z, Zhang M, Lei R, Zhang Z, Liu Y, Tse-Dinh YC, Agoulnik IU. Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation. Biochimie. PMID 31756402 DOI: 10.1016/J.Biochi.2019.11.008  0.336
2019 Wang Y, Rakela S, Chambers JW, Hua ZC, Muller MT, Nitiss JL, Tse-Dinh YC, Leng F. Kinetic Study of DNA Topoisomerases by Supercoiling-Dependent Fluorescence Quenching. Acs Omega. 4: 18413-18422. PMID 31720544 DOI: 10.1021/acsomega.9b02676  0.466
2019 Wang W, Rodriguez-Silva M, Acanda de la Rocha AM, Wolf AL, Lai Y, Liu Y, Reinhold WC, Pommier Y, Chambers JW, Tse-Dinh YC. Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents. Cancers. 11. PMID 31547492 DOI: 10.3390/Cancers11101416  0.42
2019 Wang W, Tse-Dinh YC. Recent Advances in Use of Topoisomerase Inhibitors in Combination Cancer Therapy. Current Topics in Medicinal Chemistry. PMID 30931861 DOI: 10.2174/1568026619666190401113350  0.311
2019 Jeanne Dit Fouque K, Garabedian A, Leng F, Tse-Dinh YC, Fernandez-Lima F. Microheterogeneity of Topoisomerase IA/IB and Their DNA-Bound States. Acs Omega. 4: 3619-3626. PMID 30842985 DOI: 10.1021/acsomega.8b02887  0.478
2019 Garcia PK, Annamalai T, Wang W, Bell RS, Le D, Martin Pancorbo P, Sikandar S, Seddek A, Yu X, Sun D, Uhlemann AC, Tiwari PB, Leng F, Tse-Dinh YC. Mechanism and resistance for antimycobacterial activity of a fluoroquinophenoxazine compound. Plos One. 14: e0207733. PMID 30794538 DOI: 10.1371/Journal.Pone.0207733  0.442
2018 Mills M, Tse-Dinh YC, Neuman KC. Direct observation of topoisomerase IA gate dynamics. Nature Structural & Molecular Biology. 25: 1111-1118. PMID 30478267 DOI: 10.1038/S41594-018-0158-X  0.518
2018 Cao N, Tan K, Annamalai T, Joachimiak A, Tse-Dinh YC. Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site. Nucleic Acids Research. PMID 29905859 DOI: 10.1093/Nar/Gky492  0.552
2018 Zhou Q, Gomez Hernandez ME, Fernandez-Lima F, Tse-Dinh YC. Biochemical Basis of Topoisomerase I Relaxation Activity Reduction by Nonenzymatic Lysine Acetylation. International Journal of Molecular Sciences. 19. PMID 29751635 DOI: 10.3390/Ijms19051439  0.803
2018 Gupta R, Felix CR, Akerman MP, Akerman KJ, Slabber CA, Wang W, Adams J, Shaw LN, Tse-Dinh YC, Munro OQ, Rohde KH. Gold(III) macrocycles and chelates targetingand: evidence for inhibition of topoisomerase 1A. Antimicrobial Agents and Chemotherapy. PMID 29483110 DOI: 10.1128/Aac.01696-17  0.409
2018 Sandhaus S, Chapagain PP, Tse-Dinh YC. Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays. Scientific Reports. 8: 1437. PMID 29362471 DOI: 10.1038/S41598-018-19944-4  0.347
2018 Tiwari P, Chapagain P, Tse-Dinh Y, Uren A. Covalent Complex Model of DNA Topoisomerase and DNA for Molecular Dynamics Simulation Biophysical Journal. 114: 340a. DOI: 10.1016/J.Bpj.2017.11.1898  0.479
2017 Liu Y, Berrido AM, Hua ZC, Tse-Dinh YC, Leng F. Biochemical and biophysical properties of positively supercoiled DNA. Biophysical Chemistry. PMID 28887044 DOI: 10.1016/J.Bpc.2017.08.008  0.545
2017 Banda S, Cao N, Tse-Dinh YC. Distinct Mechanism Evolved for Mycobacterial RNA Polymerase and Topoisomerase I Protein-Protein Interaction. Journal of Molecular Biology. PMID 28843989 DOI: 10.1016/J.Jmb.2017.08.011  0.397
2017 Ranjan N, Story S, Fulcrand G, Leng F, Ahmad M, King A, Sur S, Wang W, Tse-Dinh YC, Arya DP. Selective Inhibition of E. coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono and Bisbenzimidazoles. Journal of Medicinal Chemistry. PMID 28513176 DOI: 10.1021/Acs.Jmedchem.7B00191  0.545
2017 Zhou Q, Zhou YN, Jin DJ, Tse-Dinh YC. Deacetylation of topoisomerase I is an important physiological function of E. coli CobB. Nucleic Acids Research. PMID 28398568 DOI: 10.1093/Nar/Gkx250  0.795
2017 Liu D, Shao Y, Chen G, Tse-Dinh YC, Piccirilli JA, Weizmann Y. Synthesizing topological structures containing RNA. Nature Communications. 8: 14936. PMID 28361879 DOI: 10.1038/Ncomms14936  0.399
2016 Cheng B, Zhou Q, Weng L, Leszyk JD, Greenberg MM, Tse-Dinh YC. Identification of proximal sites for unwound DNA substrate in E. coli topoisomerase I with oxidative crosslinking. Febs Letters. PMID 27926785 DOI: 10.1002/1873-3468.12517  0.806
2016 Yu X, Zhang M, Annamalai T, Bansod P, Narula G, Tse-Dinh YC, Sun D. Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial topoisomerase IA inhibitors. European Journal of Medicinal Chemistry. 125: 515-527. PMID 27689733 DOI: 10.1016/J.Ejmech.2016.09.053  0.673
2016 Tiwari PB, Chapagain PP, Banda S, Darici Y, Üren A, Tse-Dinh YC. Characterization of molecular interactions between E. coli RNA polymerase and topoisomerase I by molecular simulations. Febs Letters. PMID 27448274 DOI: 10.1002/1873-3468.12321  0.37
2016 Tse-Dinh YC. Targeting bacterial topoisomerases - how to counter mechanisms of resistance. Future Medicinal Chemistry. PMID 27285067 DOI: 10.4155/Fmc-2016-0042  0.327
2016 Ahmad M, Xue Y, Lee SK, Martindale JL, Shen W, Li W, Zou S, Ciaramella M, Debat H, Nadal M, Leng F, Zhang H, Wang Q, Siaw GE, Niu H, ... ... Tse-Dinh YC, et al. RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals. Nucleic Acids Research. PMID 27257063 DOI: 10.1093/Nar/Gkw508  0.447
2016 Sandhaus S, Annamalai T, Welmaker G, Houghten RA, Paz C, Garcia PK, Andres A, Narula G, Rodrigues Felix C, Geden S, Netherton M, Gupta R, Rohde KH, Giulianotti MA, Tse-Dinh YC. Small Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents. Antimicrobial Agents and Chemotherapy. PMID 27114277 DOI: 10.1128/Aac.00288-16  0.721
2016 Banda S, Tiwari PB, Darici Y, Tse-Dinh YC. Investigating direct interaction between Escherichia coli topoisomerase I and RecA. Gene. PMID 27001450 DOI: 10.1016/J.Gene.2016.03.013  0.493
2015 Tan K, Cao N, Cheng B, Joachimiak A, Tse-Dinh YC. Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a novel protein fold. Journal of Molecular Biology. PMID 26655023 DOI: 10.1016/J.Jmb.2015.11.024  0.472
2015 Tan K, Zhou Q, Cheng B, Zhang Z, Joachimiak A, Tse-Dinh YC. Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I. Nucleic Acids Research. PMID 26490962 DOI: 10.1093/Nar/Gkv1073  0.79
2015 Yang J, Annamalai T, Cheng B, Banda S, Tyagi R, Tse-Dinh YC. Antimicrobial Susceptibility and SOS-Dependent Increase in Mutation Frequency Are Impacted by Escherichia coli Topoisomerase I C-Terminal Point Mutation. Antimicrobial Agents and Chemotherapy. 59: 6195-202. PMID 26248366 DOI: 10.1128/Aac.00855-15  0.437
2015 Tse-Dinh YC. Targeting bacterial topoisomerase I to meet the challenge of finding new antibiotics. Future Medicinal Chemistry. 7: 459-71. PMID 25875873 DOI: 10.4155/Fmc.14.157  0.333
2015 Cheng B, Annamalai T, Sandhaus S, Bansod P, Tse-Dinh YC. Inhibition of Zn(II) binding type IA topoisomerases by organomercury compounds and Hg(II). Plos One. 10: e0120022. PMID 25798600 DOI: 10.1371/Journal.Pone.0120022  0.494
2015 Tiwari P, Annamalai T, Cheng B, Narula G, Wang X, Tse-Dinh Y, He J, Darici Y. Molecular Interaction between Escherichia Coli Topoisomerase I and pBAD/Thio Supercoiled Plasmid DNA Biophysical Journal. 108: 398a. DOI: 10.1016/J.Bpj.2014.11.2181  0.755
2014 Feng L, Maddox MM, Alam MZ, Tsutsumi LS, Narula G, Bruhn DF, Wu X, Sandhaus S, Lee RB, Simmons CJ, Tse-Dinh YC, Hurdle JG, Lee RE, Sun D. Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. Journal of Medicinal Chemistry. 57: 8398-420. PMID 25238443 DOI: 10.1021/Jm500853V  0.631
2014 Tiwari PB, Annamalai T, Cheng B, Narula G, Wang X, Tse-Dinh YC, He J, Darici Y. A surface plasmon resonance study of the intermolecular interaction between Escherichia coli topoisomerase I and pBAD/Thio supercoiled plasmid DNA. Biochemical and Biophysical Research Communications. 445: 445-50. PMID 24530905 DOI: 10.1016/J.Bbrc.2014.02.015  0.756
2013 Lin H, Annamalai T, Bansod P, Tse-Dinh YC, Sun D. Synthesis and antibacterial evaluation of anziaic acid and analogues as topoisomerase I inhibitors. Medchemcomm. 4. PMID 24363888 DOI: 10.1039/C3Md00238A  0.318
2013 Aedo S, Tse-Dinh YC. SbcCD-mediated processing of covalent gyrase-DNA complex in Escherichia coli. Antimicrobial Agents and Chemotherapy. 57: 5116-9. PMID 23917316 DOI: 10.1128/Aac.00130-13  0.497
2013 Sissi C, Cheng B, Lombardo V, Tse-Dinh YC, Palumbo M. Metal ion and inter-domain interactions as functional networks in E. coli topoisomerase I. Gene. 524: 253-60. PMID 23612251 DOI: 10.1016/J.Gene.2013.04.008  0.426
2013 Cheng B, Cao S, Vasquez V, Annamalai T, Tamayo-Castillo G, Clardy J, Tse-Dinh YC. Identification of anziaic acid, a lichen depside from Hypotrachyna sp., as a new topoisomerase poison inhibitor. Plos One. 8: e60770. PMID 23593306 DOI: 10.1371/Journal.Pone.0060770  0.455
2012 Bansal S, Sinha D, Singh M, Cheng B, Tse-Dinh YC, Tandon V. 3,4-dimethoxyphenyl bis-benzimidazole, a novel DNA topoisomerase inhibitor that preferentially targets Escherichia coli topoisomerase I. The Journal of Antimicrobial Chemotherapy. 67: 2882-91. PMID 22945915 DOI: 10.1093/Jac/Dks322  0.468
2012 Aedo S, Tse-Dinh YC. Isolation and quantitation of topoisomerase complexes accumulated on Escherichia coli chromosomal DNA. Antimicrobial Agents and Chemotherapy. 56: 5458-64. PMID 22869559 DOI: 10.1128/Aac.01182-12  0.544
2012 Narula G, Tse-Dinh YC. Residues of E. coli topoisomerase I conserved for interaction with a specific cytosine base to facilitate DNA cleavage. Nucleic Acids Research. 40: 9233-43. PMID 22833607 DOI: 10.1093/Nar/Gks688  0.754
2011 Liu IF, Aedo S, Tse-Dinh YC. Resistance to topoisomerase cleavage complex induced lethality in Escherichia coli via titration of transcription regulators PurR and FNR. Bmc Microbiology. 11: 261. PMID 22152010 DOI: 10.1186/1471-2180-11-261  0.668
2011 Casu L, Cottiglia F, Leonti M, De Logu A, Agus E, Tse-Dinh YC, Lombardo V, Sissi C. Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Bioorganic & Medicinal Chemistry Letters. 21: 7041-4. PMID 22014547 DOI: 10.1016/J.Bmcl.2011.09.097  0.404
2011 Liu IF, Sutherland JH, Cheng B, Tse-Dinh YC. Topoisomerase I function during Escherichia coli response to antibiotics and stress enhances cell killing from stabilization of its cleavage complex. The Journal of Antimicrobial Chemotherapy. 66: 1518-24. PMID 21486853 DOI: 10.1093/Jac/Dkr150  0.634
2011 Zhang Z, Cheng B, Tse-Dinh YC. Crystal structure of a covalent intermediate in DNA cleavage and rejoining by Escherichia coli DNA topoisomerase I. Proceedings of the National Academy of Sciences of the United States of America. 108: 6939-44. PMID 21482796 DOI: 10.1073/Pnas.1100300108  0.596
2011 Narula G, Annamalai T, Aedo S, Cheng B, Sorokin E, Wong A, Tse-Dinh YC. The strictly conserved Arg-321 residue in the active site of Escherichia coli topoisomerase I plays a critical role in DNA rejoining. The Journal of Biological Chemistry. 286: 18673-80. PMID 21478161 DOI: 10.1074/Jbc.M111.229450  0.78
2010 Narula G, Becker J, Cheng B, Dani N, Abrenica MV, Tse-Dinh YC. The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites. Bmc Biochemistry. 11: 41. PMID 20920291 DOI: 10.1186/1471-2091-11-41  0.739
2010 Sutherland JH, Tse-Dinh YC. Analysis of RuvABC and RecG involvement in the escherichia coli response to the covalent topoisomerase-DNA complex. Journal of Bacteriology. 192: 4445-51. PMID 20601468 DOI: 10.1128/Jb.00350-10  0.557
2009 Liu IF, Annamalai T, Sutherland JH, Tse-Dinh YC. Hydroxyl radicals are involved in cell killing by the bacterial topoisomerase I cleavage complex. Journal of Bacteriology. 191: 5315-9. PMID 19525344 DOI: 10.1128/Jb.00559-09  0.643
2009 Annamalai T, Dani N, Cheng B, Tse-Dinh YC. Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol. Bmc Biochemistry. 10: 18. PMID 19519900 DOI: 10.1186/1471-2091-10-18  0.459
2009 Tse-Dinh YC. Bacterial topoisomerase I as a target for discovery of antibacterial compounds. Nucleic Acids Research. 37: 731-7. PMID 19042977 DOI: 10.1093/Nar/Gkn936  0.538
2009 Cheng B, Annamalai T, Sorokin E, Abrenica M, Aedo S, Tse-Dinh YC. Asp-to-Asn substitution at the first position of the DxD TOPRIM motif of recombinant bacterial topoisomerase I is extremely lethal to E. coli. Journal of Molecular Biology. 385: 558-67. PMID 19013470 DOI: 10.1016/J.Jmb.2008.10.073  0.463
2008 Sorokin EP, Cheng B, Rathi S, Aedo SJ, Abrenica MV, Tse-Dinh YC. Inhibition of Mg2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region. Nucleic Acids Research. 36: 4788-96. PMID 18653534 DOI: 10.1093/Nar/Gkn460  0.526
2008 Sutherland JH, Cheng B, Liu IF, Tse-Dinh YC. SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway. Journal of Bacteriology. 190: 3399-403. PMID 18310346 DOI: 10.1128/Jb.01674-07  0.679
2008 Cheng B, Sorokin EP, Tse-Dinh YC. Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I. Nucleic Acids Research. 36: 1017-25. PMID 18096618 DOI: 10.1093/Nar/Gkm1126  0.571
2007 Tse-Dinh YC. Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases Infectious Disorders - Drug Targets. 7: 3-9. PMID 17346206  0.407
2007 Cheng B, Liu IF, Tse-Dinh YC. Compounds with antibacterial activity that enhance DNA cleavage by bacterial DNA topoisomerase I. The Journal of Antimicrobial Chemotherapy. 59: 640-5. PMID 17317696 DOI: 10.1093/Jac/Dkl556  0.735
2006 Strahs D, Zhu CX, Cheng B, Chen J, Tse-Dinh YC. Experimental and computational investigations of Ser10 and Lys13 in the binding and cleavage of DNA substrates by Escherichia coli DNA topoisomerase I. Nucleic Acids Research. 34: 1785-97. PMID 16582104 DOI: 10.1093/Nar/Gkl109  0.579
2006 Lia G, Praly E, Ferreira H, Stockdale C, Tse-Dinh YC, Dunlap D, Croquette V, Bensimon D, Owen-Hughes T. Direct observation of DNA distortion by the RSC complex. Molecular Cell. 21: 417-25. PMID 16455496 DOI: 10.1016/J.Molcel.2005.12.013  0.437
2005 Cheng B, Shukla S, Vasunilashorn S, Mukhopadhyay S, Tse-Dinh YC. Bacterial cell killing mediated by topoisomerase I DNA cleavage activity. The Journal of Biological Chemistry. 280: 38489-95. PMID 16159875 DOI: 10.1074/Jbc.M509722200  0.528
2005 Stewart N, Feng J, Liu X, Chaudhuri D, Foster JW, Drolet M, Tse-Dinh YC. Loss of topoisomerase I function affects the RpoS-dependent and GAD systems of acid resistance in Escherichia coli. Microbiology (Reading, England). 151: 2783-91. PMID 16079354 DOI: 10.1099/Mic.0.28022-0  0.307
2004 Baaklini I, Hraiky C, Rallu F, Tse-Dinh YC, Drolet M. RNase HI overproduction is required for efficient full-length RNA synthesis in the absence of topoisomerase I in Escherichia coli. Molecular Microbiology. 54: 198-211. PMID 15458416 DOI: 10.1111/J.1365-2958.2004.04258.X  0.415
2004 Cheng B, Feng J, Mulay V, Gadgil S, Tse-Dinh YC. Site-directed mutagenesis of residues involved in G Strand DNA binding by Escherichia coli DNA topoisomerase I. The Journal of Biological Chemistry. 279: 39207-13. PMID 15215234 DOI: 10.1074/Jbc.M405891200  0.513
2004 Cheng B, Feng J, Gadgil S, Tse-Dinh YC. Flexibility at Gly-194 is required for DNA cleavage and relaxation activity of Escherichia coli DNA topoisomerase I. The Journal of Biological Chemistry. 279: 8648-54. PMID 14711811 DOI: 10.1074/jbc.M312095200  0.487
2003 Cheng B, Zhu CX, Ji C, Ahumada A, Tse-Dinh YC. Direct interaction between Escherichia coli RNA polymerase and the zinc ribbon domains of DNA topoisomerase I. The Journal of Biological Chemistry. 278: 30705-10. PMID 12788950 DOI: 10.1074/Jbc.M303403200  0.544
2003 Rui S, Tse-Dinh YC. Topoisomerase function during bacterial responses to environmental challenge. Frontiers in Bioscience : a Journal and Virtual Library. 8: d256-63. PMID 12456368 DOI: 10.2741/984  0.465
2002 Ahumada A, Tse-Dinh YC. The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I. Bmc Biochemistry. 3: 13. PMID 12052259 DOI: 10.1186/1471-2091-3-13  0.524
2001 Roche CJ, Tse-Dinh YC. Effect of phosphorothioate substitutions on DNA cleavage by Escherichia coli DNA topoisomerase I International Journal of Biological Macromolecules. 29: 175-180. PMID 11589970 DOI: 10.1016/S0141-8130(01)00165-9  0.563
2001 Kancherla RR, Nair JS, Ahmed T, Durrani H, Seiter K, Mannancheril A, Tse-Dinh YC. Evaluation of topotecan and etoposide for non-Hodgkin lymphoma: correlation of topoisomerase-DNA complex formation with clinical response. Cancer. 91: 463-71. PMID 11169927 DOI: 10.1002/1097-0142(20010201)91:3<463::Aid-Cncr1023>3.0.Co;2-R  0.651
2000 Nair JS, Kancherla R, Seiter K, Traganos F, Tse-Dinh YC. Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies. Annals of the New York Academy of Sciences. 922: 326-9. PMID 11193914 DOI: 10.1111/J.1749-6632.2000.Tb07056.X  0.522
2000 Zhu CX, Tse-Dinh YC. The acidic triad conserved in type IA DNA topoisomerases is required for binding of Mg(II) and subsequent conformational change Journal of Biological Chemistry. 275: 5318-5322. PMID 10681504 DOI: 10.1074/Jbc.275.8.5318  0.466
2000 Tse-Dinh YC. Increased sensitivity to oxidative challenges associated with topA deletion in Escherichia coli Journal of Bacteriology. 182: 829-832. PMID 10633122 DOI: 10.1128/Jb.182.3.829-832.2000  0.492
1999 Zhu CX, Tse-Dinh YC. Overexpression and purification of bacterial DNA topoisomerase I Methods in Molecular Biology (Clifton, N.J.). 94: 145-151. PMID 12844870 DOI: 10.1385/1-59259-259-7:145  0.552
1999 Fernandes PB, Menzel R, Hardy DJ, Tse-Dinh YC, Warren A, Elsemore DA. Microbial resistance: novel screens for a contemporary problem. Medicinal Research Reviews. 19: 559-68. PMID 10557370 DOI: 10.1002/(Sici)1098-1128(199911)19:6<559::Aid-Med6>3.0.Co;2-D  0.422
1999 Qi H, Menzel R, Tse-Dinh YC. Increased thermosensitivity associated with topoisomerase I deletion and promoter mutations in Escherichia coli. Fems Microbiology Letters. 178: 141-6. PMID 10483733 DOI: 10.1111/J.1574-6968.1999.Tb13770.X  0.347
1998 Ahumada A, Tse-Dinh YC. The Zn(II) binding motifs of E. coli DNA topoisomerase I is part of a high-affinity DNA binding domain. Biochemical and Biophysical Research Communications. 251: 509-14. PMID 9792804 DOI: 10.1006/Bbrc.1998.9500  0.472
1998 Tse-Dinh YC. Bacterial and archeal type I topoisomerases Biochimica Et Biophysica Acta - Gene Structure and Expression. 1400: 19-27. PMID 9748482 DOI: 10.1016/S0167-4781(98)00125-0  0.563
1998 Zhu CX, Roche CJ, Papanicolaou N, DiPietrantonio A, Tse-Dinh YC. Site-directed mutagenesis of conserved aspartates, glutamates and arginines in the active site region of Escherichia coli DNA topoisomerase I Journal of Biological Chemistry. 273: 8783-8789. PMID 9535856 DOI: 10.1074/jbc.273.15.8783  0.519
1997 Tse-Dinh YC, Qi H, Menzel R. DNA supercoiling and bacterial adaptation: thermotolerance and thermoresistance. Trends in Microbiology. 5: 323-6. PMID 9263411 DOI: 10.1016/S0966-842X(97)01080-9  0.463
1997 Zhu CX, Roche CJ, Tse-Dinh YC. Effect of Mg(II) binding on the structure and activity of Escherichia coli DNA topoisomerase I Journal of Biological Chemistry. 272: 16206-16210. PMID 9195920 DOI: 10.1074/Jbc.272.26.16206  0.441
1997 Qi H, Menzel R, Tse-Dinh YC. Regulation of Escherichia coli topA gene transcription: involvement of a sigmaS-dependent promoter. Journal of Molecular Biology. 267: 481-9. PMID 9126832 DOI: 10.1006/Jmbi.1997.0901  0.311
1996 Qi H, Menzel R, Tse-Dinh YC. Effect of the deletion of the sigma 32-dependent promoter (P1) of the Escherichia coli topoisomerase I gene on thermotolerance. Molecular Microbiology. 21: 703-11. PMID 8878034 DOI: 10.1046/J.1365-2958.1996.241390.X  0.395
1996 Yu L, Zhu CX, Tse-Dinh YC, Fesik SW. Backbone dynamics of the C-terminal domain of Escherichia coli topoisomerase I in the absence and presence of single-stranded DNA Biochemistry. 35: 9661-9666. PMID 8703937 DOI: 10.1021/Bi960507F  0.421
1996 Fernandez-Beros ME, Tse-Dinh YC. Vaccinia virus DNA topoisomerase I preferentially removes positive supercoils from DNA Febs Letters. 384: 265-268. PMID 8617368 DOI: 10.1016/0014-5793(96)00317-1  0.518
1995 Du SM, Wang H, Tse-Dinh YC, Seeman NC. Topological transformations of synthetic DNA knots. Biochemistry. 34: 673-82. PMID 7819263 DOI: 10.1021/Bi00002A035  0.519
1995 Yu L, Zhu CX, Tse-Dinh YC, Fesik SW. Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I. Biochemistry. 34: 7622-8. PMID 7779808 DOI: 10.1021/Bi00023A008  0.524
1995 Zhu CX, Samuel M, Pound A, Ahumada A, Tse-Dinh YC. Expression and DNA-binding properties of the 14K carboxyl terminal fragment of Escherichia coli DNA topoisomerase I. Biochemistry and Molecular Biology International. 35: 375-85. PMID 7663393  0.461
1995 Zhu CX, Qi HY, Tse-Dinh YC. Mutation in Cys662 of Escherichia coli DNA topoisomerase I confers temperature sensitivity and change in DNA cleavage selectivity Journal of Molecular Biology. 250: 609-616. PMID 7623379 DOI: 10.1006/Jmbi.1995.0402  0.501
1995 Yu L, Zhu CX, Tse-Dinh YC, Fesik SW. Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I Biochemistry. 34: 7622-7628.  0.425
1994 Gupta M, Zhu CX, Tse-Dinh YC. Mutations of vaccinia virus DNA topoisomerase I that stabilize the cleavage complex Journal of Biological Chemistry. 269: 573-578. PMID 8276853  0.43
1994 Fu TJ, Tse-Dinh YC, Seeman NC. Holliday junction crossover topology. Journal of Molecular Biology. 236: 91-105. PMID 8107128 DOI: 10.1006/Jmbi.1994.1121  0.361
1994 Tse-Dinh YC. Biochemistry of Bacterial Type I DNA Topoisomerases Advances in Pharmacology. 29: 21-37. DOI: 10.1016/S1054-3589(08)60538-4  0.525
1993 Samuel M, Zhu CX, Villanueva GB, Tse-Dinh YC. Effect of zinc removal on the conformation of Escherichia coli DNA topoisomerase I Archives of Biochemistry and Biophysics. 300: 302-308. PMID 8380965 DOI: 10.1006/abbi.1993.1042  0.417
1992 Gupta M, Zhu CX, Tse-Dinh YC. An engineered mutant of vaccinia virus DNA topoisomerase I is sensitive to the anti-cancer drug camptothecin Journal of Biological Chemistry. 267: 24177-24180. PMID 1332948  0.424
1992 Fernandez-Beros ME, Tse-Dinh YC. Conditional growth of Escherichia coli caused by expression of vaccinia virus DNA topoisomerase I Journal of Bacteriology. 174: 7059-7062. PMID 1328167 DOI: 10.1128/Jb.174.21.7059-7062.1992  0.353
1991 Tse-Dinh YC. Zinc(II) coordination in Escherichia coli DNA topoisomerase I is required for cleavable complex formation with DNA Journal of Biological Chemistry. 266: 14317-14320. PMID 1650356  0.497
1991 Domanico PL, Tse-Dinh YC. Mechanistic studies on E. coli DNA topoisomerase I: Divalent ion effects Journal of Inorganic Biochemistry. 42: 87-96. PMID 1649911 DOI: 10.1016/0162-0134(91)80035-G  0.354
1989 Beran-Steed RK, Tse-Dinh YC. The carboxyl terminal domain of Escherichia coli DNA topoisomerase I confers higher affinity to DNA Proteins: Structure, Function and Genetics. 6: 249-258. PMID 2560191 DOI: 10.1002/Prot.340060307  0.567
1988 Domanico PL, Tse-Dinh YC. Cleavage of dT8 and dT8 phosphorothioyl analogues by Escherichia coli DNA topoisomerase I: Product and rate analysis Biochemistry. 27: 6365-6371. PMID 2851323  0.313
1988 Tse-Dinh YC, Beran-Steed RK. Escherichia coli DNA topoisomerase I is a zinc metalloprotein with three repetitive zinc-binding domains Journal of Biological Chemistry. 263: 15857-15859. PMID 2846526  0.455
1988 Tse-Dinh YC, Beran RK. Multiple promoters for transcription of the Escherichia coli DNA topoisomerase I gene and their regulation by DNA supercoiling Journal of Molecular Biology. 202: 735-742. PMID 2845101 DOI: 10.1016/0022-2836(88)90554-2  0.347
1987 Tse-Dinh YC, McGee LR. Light-induced modifications of DNA by gilvocarcin V and its aglycone Biochemical and Biophysical Research Communications. 143: 808-812. PMID 3566756 DOI: 10.1016/0006-291X(87)90320-2  0.522
1986 Tse-Dinh YC, Wang JC. Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I Journal of Molecular Biology. 191: 321-331. PMID 3029379 DOI: 10.1016/0022-2836(86)90129-4  0.537
1985 Tse-Dinh YC. Regulation of the Escherichia coli DNA topoisomerase I gene by DNA supercolling Nucleic Acids Research. 13: 4751-4763. PMID 2991845 DOI: 10.1093/Nar/13.13.4751  0.518
1984 Tse-Dinh YC, Wong TW, Goldberg AR. Virus- and cell-encoded tyrosine protein kinases inactivate DNA topoisomerases in vitro Nature. 312: 785-786. PMID 6096721 DOI: 10.1038/312785A0  0.489
1983 Tse-dinh YC, Mccarron BGH, Arentzen R, Chowdhry V. Mechanistic study of E. coli DNA topoisomerase I: Cleavage of oligonucleotides Nucleic Acids Research. 11: 8691-8701. PMID 6324095 DOI: 10.1093/nar/11.24.8691  0.482
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