| Year |
Citation |
Score |
| 2023 |
Liao EE, Yang M, Nathan Kochen N, Vunnam N, Braun AR, Ferguson DM, Sachs JN. Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular Neurobiology. PMID 37428404 DOI: 10.1007/s12035-023-03417-5 |
0.644 |
|
| 2023 |
Vunnam N, Yang M, Lo CH, Paulson C, Fiers WD, Huber E, Been M, Ferguson DM, Sachs JN. Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. Acs Bio & Med Chem Au. 3: 270-282. PMID 37363080 DOI: 10.1021/acsbiomedchemau.2c00048 |
0.683 |
|
| 2022 |
Yang M, Larson PG, Brown L, Schultz JR, Kucaba TA, Griffith TS, Ferguson DM. Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs. Bioorganic & Medicinal Chemistry Letters. 59: 128548. PMID 35051578 DOI: 10.1016/j.bmcl.2022.128548 |
0.505 |
|
| 2020 |
Kim H, Khanna V, Kucaba TA, Zhang W, Sehgal D, Ferguson DM, Griffith TS, Panyam J. TLR7/8 Agonist Loaded Nanoparticles Augment NK Cell-mediated Antibody-based Cancer Immunotherapy. Molecular Pharmaceutics. PMID 32383885 DOI: 10.1021/Acs.Molpharmaceut.0C00271 |
0.318 |
|
| 2019 |
Wang X, Zeng Y, Sheng L, Larson P, Liu X, Zou X, Wang S, Guo K, Ma C, Zhang G, Cui H, Ferguson DM, Li Y, Zhang JR, Aldrich CC. A Cinchona Alkaloid Antibiotic that Appears to Target ATP Synthase in Streptococcus pneumoniae. Journal of Medicinal Chemistry. PMID 30779564 DOI: 10.1021/Acs.Jmedchem.8B01353 |
0.341 |
|
| 2019 |
Bockman MR, Engelhart CA, Cramer JD, Howe M, Mishra N, Zimmerman M, Larson P, Alvarez-Cabrera N, Park SW, Boshoff HIM, Bean JM, Young V, Ferguson DM, Dartois V, Jarrett JT, et al. Investigation of (S)-(-)-acidomycin: A selective antimycobacterial natural product that inhibits biotin synthase. Acs Infectious Diseases. PMID 30652474 DOI: 10.1021/Acsinfecdis.8B00345 |
0.304 |
|
| 2019 |
Khanna V, Kim H, Zhang W, Larson P, Ferguson D, Panyam J. Abstract 4129: Novel small molecule TLR7/8 agonists for enhancing NK cell-mediated ADCC Cancer Research. 79: 4129-4129. DOI: 10.1158/1538-7445.Am2019-4129 |
0.364 |
|
| 2017 |
Larson P, Kucaba TA, Xiong Z, Olin M, Griffith TS, Ferguson DM. Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8. Acs Medicinal Chemistry Letters. 8: 1148-1152. PMID 29152046 DOI: 10.1021/Acsmedchemlett.7B00256 |
0.348 |
|
| 2014 |
Benoit AR, Schiaffo C, Salomon CE, Goodell JR, Hiasa H, Ferguson DM. Synthesis and evaluation of N-alkyl-9-aminoacridines with antibacterial activity. Bioorganic & Medicinal Chemistry Letters. 24: 3014-7. PMID 24908610 DOI: 10.1016/J.Bmcl.2014.05.037 |
0.74 |
|
| 2014 |
Schiaffo CE, Shi C, Xiong Z, Olin M, Ohlfest JR, Aldrich CC, Ferguson DM. Structure-activity relationship analysis of imidazoquinolines with Toll-like receptors 7 and 8 selectivity and enhanced cytokine induction. Journal of Medicinal Chemistry. 57: 339-47. PMID 24383475 DOI: 10.1021/Jm4004957 |
0.314 |
|
| 2013 |
Ferreira R, Artali R, Benoit A, Gargallo R, Eritja R, Ferguson DM, Sham YY, Mazzini S. Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines. Plos One. 8: e57701. PMID 23554865 DOI: 10.1371/Journal.Pone.0057701 |
0.754 |
|
| 2013 |
Ferreira R, Artali R, Benoit A, Gargallo R, Eritja R, Ferguson DM, Sham YY, Mazzini S. Correction: Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines Plos One. 8. DOI: 10.1371/Annotation/E49600Ba-2Cfa-45C6-9984-2B337Ad73Add |
0.718 |
|
| 2012 |
Teitelbaum AM, Gallardo JL, Bedi J, Giri R, Benoit AR, Olin MR, Morizio KM, Ohlfest JR, Remmel RP, Ferguson DM. 9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma. Cancer Chemotherapy and Pharmacology. 69: 1519-27. PMID 22402637 DOI: 10.1007/S00280-012-1855-5 |
0.734 |
|
| 2012 |
Raza A, Jacobson BA, Benoit A, Patel MR, Jay-Dixon J, Hiasa H, Ferguson DM, Kratzke RA. Novel acridine-based agents with topoisomerase II inhibitor activity suppress mesothelioma cell proliferation and induce apoptosis. Investigational New Drugs. 30: 1443-8. PMID 21789510 DOI: 10.1007/S10637-011-9720-7 |
0.756 |
|
| 2011 |
Raza A, Jacobson BA, Patel M, Benoit A, Jay-Dixon J, Ferguson DM, Kratzke RA. The effect of novel acridine-based agents with topoisomerase II inhibitor on mesothelioma cell proliferation and apoptosis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e13507. PMID 28022903 DOI: 10.1200/jco.2011.29.15_suppl.e13507 |
0.728 |
|
| 2010 |
Giri R, Goodell JR, Xing C, Benoit A, Kaur H, Hiasa H, Ferguson DM. Synthesis and cancer cell cytotoxicity of substituted xanthenes. Bioorganic & Medicinal Chemistry. 18: 1456-63. PMID 20129790 DOI: 10.1016/J.Bmc.2010.01.018 |
0.767 |
|
| 2009 |
Gálvez-Peralta M, Hackbarth JS, Flatten KS, Kaufmann SH, Hiasa H, Xing C, Ferguson DM. On the role of topoisomerase I in mediating the cytotoxicity of 9-aminoacridine-based anticancer agents. Bioorganic & Medicinal Chemistry Letters. 19: 4459-62. PMID 19501511 DOI: 10.1016/J.Bmcl.2009.05.037 |
0.406 |
|
| 2009 |
Oppegard LM, Ougolkov AV, Luchini DN, Schoon RA, Goodell JR, Kaur H, Billadeau DD, Ferguson DM, Hiasa H. Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II. European Journal of Pharmacology. 602: 223-9. PMID 19071108 DOI: 10.1016/J.Ejphar.2008.11.044 |
0.741 |
|
| 2008 |
Labello NP, Bennett EM, Ferguson DM, Aldrich CC. Quantitative three dimensional structure linear interaction energy model of 5'-O-[N-(salicyl)sulfamoyl]adenosine and the aryl acid adenylating enzyme MbtA. Journal of Medicinal Chemistry. 51: 7154-60. PMID 18959400 DOI: 10.1021/Jm800668U |
0.386 |
|
| 2008 |
Kane BE, McCurdy CR, Ferguson DM. Toward a structure-based model of salvinorin A recognition of the kappa-opioid receptor. Journal of Medicinal Chemistry. 51: 1824-30. PMID 18293909 DOI: 10.1021/Jm701040V |
0.376 |
|
| 2008 |
Goodell JR, Ougolkov AV, Hiasa H, Kaur H, Remmel R, Billadeau DD, Ferguson DM. Acridine-based agents with topoisomerase II activity inhibit pancreatic cancer cell proliferation and induce apoptosis. Journal of Medicinal Chemistry. 51: 179-82. PMID 18163538 DOI: 10.1021/Jm701228E |
0.74 |
|
| 2008 |
Kane BE, Grant MK, El-Fakahany EE, Ferguson DM. Synthesis and evaluation of xanomeline analogs--probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor. Bioorganic & Medicinal Chemistry. 16: 1376-92. PMID 17977730 DOI: 10.1016/J.Bmc.2007.10.058 |
0.349 |
|
| 2006 |
Singh N, Chevé G, Ferguson DM, McCurdy CR. A combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist. Journal of Computer-Aided Molecular Design. 20: 471-93. PMID 17009091 DOI: 10.1007/S10822-006-9067-X |
0.396 |
|
| 2006 |
Goodell JR, Madhok AA, Hiasa H, Ferguson DM. Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity. Bioorganic & Medicinal Chemistry. 14: 5467-80. PMID 16713270 DOI: 10.1016/J.Bmc.2006.04.044 |
0.741 |
|
| 2006 |
Kane BE, Nieto MJ, McCurdy CR, Ferguson DM. A unique binding epitope for salvinorin A, a non-nitrogenous kappa opioid receptor agonist. The Febs Journal. 273: 1966-74. PMID 16640560 DOI: 10.1111/J.1742-4658.2006.05212.X |
0.372 |
|
| 2006 |
Kane BE, Svensson B, Ferguson DM. Molecular recognition of opioid receptor ligands. The Aaps Journal. 8: E126-37. PMID 16584119 DOI: 10.1208/Aapsj080115 |
0.36 |
|
| 2006 |
Puig-Basagoiti F, Tilgner M, Forshey BM, Philpott SM, Espina NG, Wentworth DE, Goebel SJ, Masters PS, Falgout B, Ren P, Ferguson DM, Shi PY. Triaryl pyrazoline compound inhibits flavivirus RNA replication. Antimicrobial Agents and Chemotherapy. 50: 1320-9. PMID 16569847 DOI: 10.1128/Aac.50.4.1320-1329.2006 |
0.307 |
|
| 2006 |
Goodell JR, Svensson B, Ferguson DM. Spectrophotometric determination and computational evaluation of the rates of hydrolysis of 9-amino-substituted acridines. Journal of Chemical Information and Modeling. 46: 876-83. PMID 16563019 DOI: 10.1021/Ci050322S |
0.7 |
|
| 2006 |
Goodell JR, Puig-Basagoiti F, Forshey BM, Shi PY, Ferguson DM. Identification of compounds with anti-West Nile Virus activity. Journal of Medicinal Chemistry. 49: 2127-37. PMID 16539402 DOI: 10.1021/Jm051229Y |
0.733 |
|
| 2005 |
Puig-Basagoiti F, Deas TS, Ren P, Tilgner M, Ferguson DM, Shi PY. High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery. Antimicrobial Agents and Chemotherapy. 49: 4980-8. PMID 16304161 DOI: 10.1128/Aac.49.12.4980-4988.2005 |
0.306 |
|
| 2003 |
Park S, Seetharaman M, Ogdie A, Ferguson D, Tretyakova N. 3'-Exonuclease resistance of DNA oligodeoxynucleotides containing O6-[4-oxo-4-(3-pyridyl)butyl]guanine. Nucleic Acids Research. 31: 1984-94. PMID 12655016 DOI: 10.1093/Nar/Gkg299 |
0.613 |
|
| 2002 |
McFadyen I, Metzger T, Subramanian G, Poda G, Jorvig E, Ferguson DM. Molecular modeling of opioid receptor-ligand complexes. Progress in Medicinal Chemistry. 40: 107-35. PMID 12516524 DOI: 10.1016/S0079-6468(08)70083-3 |
0.665 |
|
| 2002 |
Mo Y, Subramanian G, Gao J, Ferguson DM. Cation-pi interactions: an energy decomposition analysis and its implication in delta-opioid receptor-ligand binding. Journal of the American Chemical Society. 124: 4832-7. PMID 11971733 DOI: 10.1021/Ja0174433 |
0.339 |
|
| 2001 |
McFadyen IJ, Metzger TG, Paterlini MG, Ferguson DM. Exploring the unique pharmacology of a novel opioid receptor, ZFOR1, using molecular modeling and the 'message-address' concept. Protein Engineering. 14: 953-60. PMID 11809925 DOI: 10.1093/Protein/14.12.953 |
0.355 |
|
| 2001 |
Sharma SK, Jones RM, Metzger TG, Ferguson DM, Portoghese PS. Transformation of a kappa-opioid receptor antagonist to a kappa-agonist by transfer of a guanidinium group from the 5'- to 6'-position of naltrindole. Journal of Medicinal Chemistry. 44: 2073-9. PMID 11405645 DOI: 10.1021/Jm010095V |
0.333 |
|
| 2001 |
Le Bourdonnec B, El Kouhen R, Poda G, Law PY, Loh HH, Ferguson DM, Portoghese PS. Covalently induced activation of the delta opioid receptor by a fluorogenic affinity label, 7'-(phthalaldehydecarboxamido)naltrindole (PNTI). Journal of Medicinal Chemistry. 44: 1017-20. PMID 11297446 DOI: 10.1021/Jm010004U |
0.312 |
|
| 2000 |
Stevens WC, Jones RM, Subramanian G, Metzger TG, Ferguson DM, Portoghese PS. Potent and selective indolomorphinan antagonists of the kappa-opioid receptor. Journal of Medicinal Chemistry. 43: 2759-69. PMID 10893314 DOI: 10.1021/Jm0000665 |
0.353 |
|
| 2000 |
Ferguson DM, Kramer S, Metzger TG, Law PY, Portoghese PS. Isosteric replacement of acidic with neutral residues in extracellular loop-2 of the kappa-opioid receptor does not affect dynorphin A(1-13) affinity and function. Journal of Medicinal Chemistry. 43: 1251-2. PMID 10753461 DOI: 10.1021/Jm990583R |
0.301 |
|
| 2000 |
Subramanian G, Paterlini MG, Portoghese PS, Ferguson DM. Molecular docking reveals a novel binding site model for fentanyl at the mu-opioid receptor. Journal of Medicinal Chemistry. 43: 381-91. PMID 10669565 DOI: 10.1021/Jm9903702 |
0.393 |
|
| 2000 |
Paterlini MG, Avitabile F, Ostrowski BG, Ferguson DM, Portoghese PS. Stereochemical requirements for receptor recognition of the mu-opioid peptide endomorphin-1. Biophysical Journal. 78: 590-9. PMID 10653774 DOI: 10.1016/S0006-3495(00)76619-7 |
0.316 |
|
| 1998 |
Podlogar BL, Paterlini MG, Ferguson DM, Leo GC, Demeter DA, Brown FK, Reitz AB. Conformational analysis of the endogenous mu-opioid agonist endomorphin-1 using NMR spectroscopy and molecular modeling. Febs Letters. 439: 13-20. PMID 9849868 DOI: 10.1016/S0014-5793(98)01202-2 |
0.342 |
|
| 1998 |
Subramanian G, Germana Paterlini M, Larson DL, Portoghese PS, Ferguson DM. Conformational analysis and automated receptor docking of selective arylacetamide-based κ-opioid agonists Journal of Medicinal Chemistry. 41: 4777-4789. PMID 9822548 DOI: 10.1021/Jm9803166 |
0.385 |
|
| 1997 |
Paterlini G, Portoghese PS, Ferguson DM. Molecular simulation of dynorphin A-(1-10) binding to extracellular loop 2 of the kappa-opioid receptor. A model for receptor activation. Journal of Medicinal Chemistry. 40: 3254-62. PMID 9379445 DOI: 10.1021/Jm970252J |
0.368 |
|
| 1997 |
Marsh A, Ferguson DM. Knowledge-based modeling of a bacterial dichloromethane dehalogenase. Proteins. 28: 217-26. PMID 9188739 DOI: 10.1002/(Sici)1097-0134(199706)28:2<217::Aid-Prot10>3.0.Co;2-L |
0.327 |
|
| 1996 |
Metzger TG, Paterlini MG, Portoghese PS, Ferguson DM. Application of the message-address concept to the docking of naltrexone and selective naltrexone-derived opioid antagonists into opioid receptor models. Neurochemical Research. 21: 1287-94. PMID 8947918 DOI: 10.1007/Bf02532369 |
0.356 |
|
| 1996 |
Paterlini MG, Metzger TG, Portoghese PS, Ferguson DM. Identification of Helical Packing Motifs Common to Bacteriorhodopsin and G Protein-Coupled Receptors Journal of Molecular Modeling. 3: 70. DOI: 10.1007/S008940050024 |
0.352 |
|
| 1995 |
Metzger TG, Ferguson DM. On the role of extracellular loops of opioid receptors in conferring ligand selectivity. Febs Letters. 375: 1-4. PMID 7498453 DOI: 10.1016/0014-5793(95)01185-H |
0.337 |
|
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