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Michael G. Kearse, Ph.D. - Publications

Affiliations: 
2013 Molecular Biology Lehigh University, Bethlehem, PA, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry, Genetics
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Scarpitti MR, Pastore B, Tang W, Kearse MG. Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP. The Journal of Biological Chemistry. 107540. PMID 38971316 DOI: 10.1016/j.jbc.2024.107540  0.488
2024 Anastas V, Chavdoula E, La Ferlita A, Soysal B, Cosentini I, Nigita G, Kearse MG, Tsichlis PN. KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation. Biorxiv : the Preprint Server For Biology. PMID 38826406 DOI: 10.1101/2024.05.22.595403  0.454
2024 Grove DJ, Russell PJ, Kearse MG. To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1·DENR to deliver initiator tRNA to ribosomes. Wiley Interdisciplinary Reviews. Rna. 15: e1833. PMID 38433101 DOI: 10.1002/wrna.1833  0.431
2024 Scarpitti MR, Pastore B, Tang W, Kearse MG. Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP. Biorxiv : the Preprint Server For Biology. PMID 38352534 DOI: 10.1101/2024.02.02.577121  0.487
2023 Scarpitti MR, Kearse MG. In vitro Analysis of Stalled Ribosomes Using Puromycin Incorporation. Bio-Protocol. 13: e4744. PMID 37638299 DOI: 10.21769/BioProtoc.4744  0.437
2023 Grove DJ, Levine DJ, Kearse MG. Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits. Nucleic Acids Research. PMID 37602404 DOI: 10.1093/nar/gkad683  0.435
2023 Russell PJ, Slivka JA, Boyle EP, Burghes AHM, Kearse MG. Translation re-initiation after uORFs does not fully protect mRNAs from nonsense-mediated decay. Rna (New York, N.Y.). PMID 36878710 DOI: 10.1261/rna.079525.122  0.422
2022 Scarpitti MR, Warrick JE, Yoder EL, Kearse MG. A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes. The Journal of Biological Chemistry. 298: 102660. PMID 36328245 DOI: 10.1016/j.jbc.2022.102660  0.419
2020 Rodriguez CM, Wright SE, Kearse MG, Haenfler JM, Flores BN, Liu Y, Ifrim MF, Glineburg MR, Krans A, Jafar-Nejad P, Sutton MA, Bassell GJ, Parent JM, Rigo F, Barmada SJ, et al. A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis. Nature Neuroscience. PMID 32066985 DOI: 10.1038/S41593-020-0590-1  0.686
2019 Green KM, Sheth U, Flores BN, Wright SE, Sutter A, Kearse MG, Barmada S, Ivanova MI, Todd PK. High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation. The Journal of Biological Chemistry. PMID 31649034 DOI: 10.1074/Jbc.Ra119.009951  0.75
2019 Kearse MG, Goldman DH, Choi J, Nwaezeapu C, Liang D, Green KM, Goldstrohm AC, Todd PK, Green R, Wilusz JE. Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes & Development. PMID 31171704 DOI: 10.1101/Gad.324715.119  0.757
2018 Li Z, Kearse MG, Huang C. The nuclear export of circular RNAs is primarily defined by their length. Rna Biology. PMID 30526278 DOI: 10.1080/15476286.2018.1557498  0.628
2018 Mageeney CM, Kearse MG, Gershman BW, Pritchard CE, Colquhoun JM, Ware VC. Functional interplay between ribosomal protein paralogues in the eRpL22 family in Drosophila melanogaster. Fly. 1-21. PMID 30465696 DOI: 10.1080/19336934.2018.1549419  0.702
2017 Green KM, Glineburg MR, Kearse MG, Flores BN, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada SJ, Todd PK. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nature Communications. 8: 2005. PMID 29222490 DOI: 10.1038/S41467-017-02200-0  0.73
2017 Kearse MG, Wilusz JE. Non-AUG translation: a new start for protein synthesis in eukaryotes. Genes & Development. 31: 1717-1731. PMID 28982758 DOI: 10.1101/Gad.305250.117  0.736
2016 Krans A, Kearse MG, Todd PK. RAN translation from antisense CCG repeats in Fragile X Tremor/Ataxia Syndrome. Annals of Neurology. PMID 27761921 DOI: 10.1002/Ana.24800  0.693
2016 Kearse MG, Green KM, Krans A, Rodriguez CM, Linsalata AE, Goldstrohm AC, Todd PK. CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins. Molecular Cell. PMID 27041225 DOI: 10.1016/J.Molcel.2016.02.034  0.709
2014 Kearse MG, Todd PK. Repeat-associated non-AUG translation and its impact in neurodegenerative disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 721-31. PMID 25005000 DOI: 10.1007/S13311-014-0292-Z  0.705
2013 Kearse MG, Ireland JA, Prem SM, Chen AS, Ware VC. RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes. Nucleus (Austin, Tex.). 4: 241-58. PMID 23778934 DOI: 10.4161/Nucl.25261  0.713
2011 Kearse MG, Chen AS, Ware VC. Expression of ribosomal protein L22e family members in Drosophila melanogaster: rpL22-like is differentially expressed and alternatively spliced. Nucleic Acids Research. 39: 2701-16. PMID 21138957 DOI: 10.1093/Nar/Gkq1218  0.741
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