| Year |
Citation |
Score |
| 2024 |
Li Z, Liu HY, He Z, Chakravarty A, Golden RP, Jiang Z, You I, Yue H, Donovan KA, Du G, Che J, Tse J, Che I, Lu W, Fischer ES, ... ... Yang PL, et al. Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2405829. PMID 39145423 DOI: 10.1002/advs.202405829 |
0.815 |
|
| 2024 |
Liu HY, Li Z, Reindl T, He Z, Qiu X, Golden RP, Donovan KA, Bailey A, Fischer ES, Zhang T, Gray NS, Yang PL. Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism. Nature Communications. 15: 5179. PMID 38898037 DOI: 10.1038/s41467-024-49161-9 |
0.821 |
|
| 2024 |
Li Z, Liu HY, He Z, Chakravarty A, Golden RP, Jiang Z, You I, Yue H, Donovan KA, Du G, Che J, Tse J, Che I, Lu W, Fischer ES, ... ... Yang PL, et al. Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Biorxiv : the Preprint Server For Biology. PMID 38854003 DOI: 10.1101/2024.06.01.596987 |
0.814 |
|
| 2022 |
Chakravarty A, Yang PL. Targeted protein degradation as an antiviral approach. Antiviral Research. 105480. PMID 36567024 DOI: 10.1016/j.antiviral.2022.105480 |
0.357 |
|
| 2022 |
Boytz R, Słabicki M, Ramaswamy S, Patten JJ, Zou C, Meng C, Hurst BL, Wang J, Nowak RP, Yang PL, Sattler M, Stone RM, Griffin JD, Gray NS, Gummuluru S, et al. Anti-SARS-CoV-2 Activity of Targeted Kinase Inhibitors: Repurposing Clinically Available Drugs for COVID-19 Therapy. Journal of Medical Virology. PMID 36117402 DOI: 10.1002/jmv.28157 |
0.433 |
|
| 2021 |
Liu HY, Yang PL. Small-Molecule Inhibition of Viral Fusion Glycoproteins. Annual Review of Virology. PMID 34197186 DOI: 10.1146/annurev-virology-022221-063725 |
0.801 |
|
| 2021 |
Yang PL. Antiviral Therapeutics. Acs Infectious Diseases. PMID 34061494 DOI: 10.1021/acsinfecdis.1c00271 |
0.302 |
|
| 2020 |
de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL. A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation. The Journal of Biological Chemistry. 295: 1694-1703. PMID 33485559 DOI: 10.1074/jbc.RA119.011132 |
0.364 |
|
| 2020 |
Weisberg E, Parent A, Yang PL, Sattler M, Liu Q, Liu Q, Wang J, Meng C, Buhrlage SJ, Gray N, Griffin JD. Repurposing of Kinase Inhibitors for Treatment of COVID-19. Pharmaceutical Research. 37: 167. PMID 32778962 DOI: 10.1007/S11095-020-02851-7 |
0.515 |
|
| 2020 |
Yang PL. Call for Papers: Antiviral Therapeutics Acs Infectious Diseases. PMID 32646218 DOI: 10.1021/Acsinfecdis.0C00399 |
0.333 |
|
| 2020 |
Tallorin L, Villareal VA, Hsia CY, Rodgers MA, Burri DJ, Pfeil MP, Llopis PM, Lindenbach BD, Yang PL. Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase. The Journal of Biological Chemistry. PMID 32641492 DOI: 10.1074/Jbc.Ra120.013455 |
0.748 |
|
| 2020 |
Weisberg E, Sattler M, Yang PL, Parent A, Gray N, Griffin JD. Current Therapies Under Investigation for COVID-19. Canadian Journal of Physiology and Pharmacology. PMID 32640179 DOI: 10.1139/Cjpp-2020-0286 |
0.471 |
|
| 2020 |
Ramanathan HN, Zhang S, Douam F, Mar KB, Chang J, Yang PL, Schoggins JW, Ploss A, Lindenbach BD. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. Mbio. 11. PMID 32291299 DOI: 10.1128/Mbio.00467-20 |
0.479 |
|
| 2019 |
de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL. A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation. The Journal of Biological Chemistry. PMID 31914414 DOI: 10.1074/Jbc.Ra119.011132 |
0.821 |
|
| 2019 |
Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Correction to Discovery of Immunologically Inspired Small Molecules That Target the Viral Envelope Protein. Acs Infectious Diseases. PMID 31675213 DOI: 10.1021/Acsinfecdis.9B00401 |
0.801 |
|
| 2019 |
de Wispelaere M, Du G, Donovan KA, Zhang T, Eleuteri NA, Yuan JC, Kalabathula J, Nowak RP, Fischer ES, Gray NS, Yang PL. Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations. Nature Communications. 10: 3468. PMID 31371704 DOI: 10.1038/S41467-019-11429-W |
0.63 |
|
| 2019 |
Pitts J, Hsia CY, Lian W, Wang J, Pfeil MP, Kwiatkowski N, Li Z, Jang J, Gray NS, Yang PL. Identification of small molecule inhibitors targeting the Zika virus envelope protein. Antiviral Research. PMID 30771406 DOI: 10.1016/J.Antiviral.2019.02.008 |
0.827 |
|
| 2019 |
Schmidt AG, Lee K, Yang PL, Harrison SC. Correction: Small-Molecule Inhibitors of Dengue-Virus Entry. Plos Pathogens. 15: e1007553. PMID 30703168 DOI: 10.1371/Journal.Ppat.1007553 |
0.689 |
|
| 2019 |
Li PC, Jang J, Hsia CY, Groomes P, Lian W, de Wispelaere M, Pitts JD, Wang J, Kwaitkowski N, Gray NS, Yang PL. Small molecules targeting the flavivirus E protein with broad-spectrum activity and antiviral efficacy in vivo. Acs Infectious Diseases. PMID 30608640 DOI: 10.1021/Acsinfecdis.8B00322 |
0.821 |
|
| 2018 |
Lian W, Jang J, Potisopon S, Li PC, Rahmeh A, Wang J, Kwiatkowski NP, Gray NS, Yang PL. Discovery of Immunologically Inspired Small Molecules that Target the Viral Envelope Protein. Acs Infectious Diseases. PMID 30027735 DOI: 10.1021/Acsinfecdis.8B00127 |
0.828 |
|
| 2018 |
Chao LH, Jang J, Johnson A, Nguyen A, Gray N, Yang PL, Harrison SC. How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion. Elife. 7. PMID 29999491 DOI: 10.7554/Elife.36461 |
0.684 |
|
| 2018 |
de Wispelaere M, Lian W, Potisopon S, Li PC, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, ... Yang PL, et al. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology. PMID 29937406 DOI: 10.1016/J.Chembiol.2018.05.011 |
0.776 |
|
| 2018 |
Chao LH, Jang J, Johnson A, Nguyen A, Gray NS, Yang PL, Harrison SC. Author response: How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion Elife. DOI: 10.7554/Elife.36461.014 |
0.613 |
|
| 2017 |
Pitts JD, Li PC, de Wispelaere M, Yang PL. Antiviral activity of fenretinide against Zika virus. Antiviral Research. PMID 29051080 DOI: 10.1016/J.Antiviral.2017.10.014 |
0.708 |
|
| 2017 |
Liang Y, de Wispelaere M, Carocci M, Liu Q, Wang J, Yang PL, Gray NS. Structure-Activity Relationship Study of QL47: A Broad-Spectrum Antiviral Agent. Acs Medicinal Chemistry Letters. 8: 344-349. PMID 28337328 DOI: 10.1021/Acsmedchemlett.7B00008 |
0.587 |
|
| 2016 |
de Wispelaere M, Carocci M, Liang Y, Liu Q, Sun E, Vetter ML, Wang J, Gray NS, Yang PL. Discovery of host-targeted covalent inhibitors of dengue virus. Antiviral Research. PMID 28034743 DOI: 10.1016/J.Antiviral.2016.12.017 |
0.648 |
|
| 2016 |
Costello DA, Villareal VA, Yang PL. Desmosterol Increases Lipid Bilayer Fluidity during Hepatitis C Virus Infection. Acs Infectious Diseases. 2: 852-862. PMID 27933788 DOI: 10.1021/Acsinfecdis.6B00086 |
0.805 |
|
| 2016 |
Villareal VA, Fu D, Costello DA, Xie XS, Yang PL. Hepatitis C Virus Selectively Alters the Intracellular Localization of Desmosterol. Acs Chemical Biology. PMID 27128812 DOI: 10.1021/Acschembio.6B00324 |
0.813 |
|
| 2016 |
Clark MJ, Miduturu C, Schmidt AG, Zhu X, Pitts JD, Wang J, Potisopon S, Zhang J, Wojciechowski A, Hann Chu JJ, Gray NS, Yang PL. GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein. Cell Chemical Biology. 23: 443-452. PMID 27105280 DOI: 10.1016/J.Chembiol.2016.03.010 |
0.803 |
|
| 2016 |
Chou YY, Cuevas C, Carocci M, Stubbs SH, Ma M, Cureton DK, Chao L, Evesson F, He K, Yang PL, Whelan SP, Ross SR, Kirchhausen T, Gaudin R. Identification and characterization of a novel broad spectrum virus entry inhibitor. Journal of Virology. PMID 26912630 DOI: 10.1128/Jvi.00103-16 |
0.506 |
|
| 2016 |
Carocci M, Yang PL. Lactimidomycin is a broad-spectrum inhibitor of dengue and other RNA viruses. Antiviral Research. PMID 26872864 DOI: 10.1016/J.Antiviral.2016.02.005 |
0.511 |
|
| 2015 |
Villareal VA, Rodgers MA, Costello DA, Yang PL. Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C viruses. Antiviral Research. PMID 26526588 DOI: 10.1016/J.Antiviral.2015.10.013 |
0.819 |
|
| 2015 |
Carocci M, Hinshaw SM, Rodgers MA, Villareal VA, Burri DJ, Pilankatta R, Maharaj NP, Gack MU, Stavale EJ, Warfield KL, Yang PL. The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication. Antimicrobial Agents and Chemotherapy. 59: 85-95. PMID 25313218 DOI: 10.1128/Aac.04177-14 |
0.798 |
|
| 2015 |
Carocci M, Yang PL, Kuhn JH. Flaviviruses: Introduction to dengue viruses Global Virology I-Identifying and Investigating Viral Diseases. 403-424. DOI: 10.1007/978-1-4939-2410-3_15 |
0.331 |
|
| 2014 |
Vetter ML, Zhang Z, Liu S, Wang J, Cho H, Zhang J, Zhang W, Gray NS, Yang PL. Fluorescent visualization of Src by using dasatinib-BODIPY. Chembiochem : a European Journal of Chemical Biology. 15: 1317-24. PMID 24828915 DOI: 10.1002/Cbic.201402010 |
0.458 |
|
| 2013 |
de Wispelaere M, LaCroix AJ, Yang PL. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. Journal of Virology. 87: 7367-81. PMID 23616652 DOI: 10.1128/Jvi.00632-13 |
0.476 |
|
| 2012 |
Vetter ML, Rodgers MA, Patricelli MP, Yang PL. Chemoproteomic profiling identifies changes in DNA-PK as markers of early dengue virus infection. Acs Chemical Biology. 7: 2019-26. PMID 22999307 DOI: 10.1021/Cb300420Z |
0.641 |
|
| 2012 |
Zhang Z, Kwiatkowski N, Zeng H, Lim SM, Gray NS, Zhang W, Yang PL. Leveraging kinase inhibitors to develop small molecule tools for imaging kinases by fluorescence microscopy. Molecular Biosystems. 8: 2523-6. PMID 22673640 DOI: 10.1039/C2Mb25099C |
0.458 |
|
| 2012 |
de Wispelaere M, Yang PL. Mutagenesis of the DI/DIII linker in dengue virus envelope protein impairs viral particle assembly. Journal of Virology. 86: 7072-83. PMID 22532681 DOI: 10.1128/Jvi.00224-12 |
0.454 |
|
| 2012 |
Schmidt AG, Lee K, Yang PL, Harrison SC. Small-molecule inhibitors of dengue-virus entry. Plos Pathogens. 8: e1002627. PMID 22496653 DOI: 10.1371/Journal.Ppat.1002627 |
0.72 |
|
| 2012 |
Rodgers MA, Villareal VA, Schaefer EA, Peng LF, Corey KE, Chung RT, Yang PL. Lipid metabolite profiling identifies desmosterol metabolism as a new antiviral target for hepatitis C virus. Journal of the American Chemical Society. 134: 6896-9. PMID 22480142 DOI: 10.1021/Ja207391Q |
0.817 |
|
| 2011 |
Yang PL, Gao M, Lin K, Liu Q, Villareal VA. Anti-HCV drugs in the pipeline. Current Opinion in Virology. 1: 607-16. PMID 22440918 DOI: 10.1016/J.Coviro.2011.10.019 |
0.78 |
|
| 2010 |
Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of flavivirus entry derived from the E protein stem. Journal of Virology. 84: 12549-54. PMID 20881042 DOI: 10.1128/Jvi.01440-10 |
0.671 |
|
| 2010 |
Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late-stage fusion intermediate. Plos Pathogens. 6: e1000851. PMID 20386713 DOI: 10.1371/Journal.Ppat.1000851 |
0.703 |
|
| 2010 |
Yang PL, Althage A, Chung J, Maier H, Wieland S, Isogawa M, Chisari FV. Immune effectors required for hepatitis B virus clearance. Proceedings of the National Academy of Sciences of the United States of America. 107: 798-802. PMID 20080755 DOI: 10.1073/Pnas.0913498107 |
0.56 |
|
| 2010 |
Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late- stage fusion intermediate Plos Pathogens. 6: 1-11. |
0.669 |
|
| 2009 |
Sessions OM, Barrows NJ, Souza-Neto JA, Robinson TJ, Hershey CL, Rodgers MA, Ramirez JL, Dimopoulos G, Yang PL, Pearson JL, Garcia-Blanco MA. Discovery of insect and human dengue virus host factors. Nature. 458: 1047-50. PMID 19396146 DOI: 10.1038/Nature07967 |
0.666 |
|
| 2009 |
Rodgers MA, Saghatelian A, Yang PL. Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling. Journal of the American Chemical Society. 131: 5030-1. PMID 19301856 DOI: 10.1021/Ja809949R |
0.692 |
|
| 2009 |
Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Reviews. Cancer. 9: 28-39. PMID 19104514 DOI: 10.1038/Nrc2559 |
0.477 |
|
| 2008 |
Hwang YC, Chu JJ, Yang PL, Chen W, Yates MV. Rapid identification of inhibitors that interfere with poliovirus replication using a cell-based assay. Antiviral Research. 77: 232-6. PMID 18243348 DOI: 10.1016/J.Antiviral.2007.12.009 |
0.605 |
|
| 2007 |
Chu JJ, Yang PL. c-Src protein kinase inhibitors block assembly and maturation of dengue virus. Proceedings of the National Academy of Sciences of the United States of America. 104: 3520-5. PMID 17360676 DOI: 10.1073/Pnas.0611681104 |
0.683 |
|
| 2002 |
Yang PL, Althage A, Chung J, Chisari FV. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 13825-30. PMID 12374864 DOI: 10.1073/Pnas.202398599 |
0.612 |
|
| 2002 |
Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG. Development of a genetic selection for catalytic antibodies. Bioorganic & Medicinal Chemistry Letters. 12: 1691-4. PMID 12039592 DOI: 10.1016/S0960-894X(02)00198-1 |
0.752 |
|
| 2002 |
Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG. Corrigendum to “Development of a Genetic Selection for Catalytic Antibodies” [Bioorg. Med. Chem. Lett. 12 (2002) 1691]† Bioorganic & Medicinal Chemistry Letters. 12: 2789. DOI: 10.1016/S0960-894X(02)00562-0 |
0.744 |
|
| 2001 |
Yin J, Mundorff EC, Yang PL, Wendt KU, Hanway D, Stevens RC, Schultz PG. A comparative analysis of the immunological evolution of antibody 28B4. Biochemistry. 40: 10764-73. PMID 11535051 DOI: 10.1021/Bi010536C |
0.664 |
|
| 1999 |
Yang PL, Schultz PG. Mutational analysis of the affinity maturation of antibody 48G7. Journal of Molecular Biology. 294: 1191-201. PMID 10600377 DOI: 10.1006/Jmbi.1999.3197 |
0.662 |
|
| 1996 |
Patten PA, Gray NS, Yang PL, Marks CB, Wedemayer GJ, Boniface JJ, Stevens RC, Schultz PG. The immunological evolution of catalysis. Science (New York, N.Y.). 271: 1086-91. PMID 8599084 DOI: 10.1126/Science.271.5252.1086 |
0.753 |
|
| 1995 |
Ulrich HD, Patten PA, Yang PL, Romesberg FE, Schultz PG. Expression studies of catalytic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 92: 11907-11. PMID 8524873 DOI: 10.1073/Pnas.92.25.11907 |
0.749 |
|
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