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Emmanuel Datan, Ph.D. - Publications

Affiliations: 
2014-2019 Pharmacology and Molecular Sciences Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 2020- Institute for Cell Engineering Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
chemical biology, oxygen biology, transcription, epigenetics, cancer, structural biology, virology, virus-host interaction
Website:
https://www.researchgate.net/profile/Emmanuel_Datan
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang Y, Salman S, Dordai D, Lyu Y, Datan E, Drehmer D, Huang TY, Hwang Y, Semenza GL. Pharmacologic HIF stabilization activates costimulatory receptor expression to increase antitumor efficacy of adoptive T cell therapy. Science Advances. 10: eadq2366. PMID 39196939 DOI: 10.1126/sciadv.adq2366  0.413
2024 Lyu Y, Yang Y, Talwar V, Lu H, Chen C, Salman S, Wicks EE, Huang TY, Drehmer D, Wang Y, Zuo Q, Datan E, Jackson W, Dordai D, Wang R, et al. Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes. Cell Reports. 43: 113972. PMID 38517892 DOI: 10.1016/j.celrep.2024.113972  0.413
2023 Zuo Q, Yang Y, Lyu Y, Yang C, Chen C, Salman S, Huang TY, Wicks EE, Jackson W, Datan E, Qin W, Semenza GL. Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis. Cell Reports. 42: 112164. PMID 36857181 DOI: 10.1016/j.celrep.2023.112164  0.399
2022 Yang Y, Chen C, Zuo Q, Lu H, Salman S, Lyu Y, Huang TY, Wicks EE, Jackson W, Datan E, Wang R, Wang Y, Le N, Zhu Y, Qin W, et al. NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification. Science Advances. 8: eabo5000. PMID 36490339 DOI: 10.1126/sciadv.abo5000  0.422
2022 Salman S, Meyers DJ, Wicks EE, Lee SN, Datan E, Thomas AM, Anders NM, Hwang Y, Lyu Y, Yang Y, Jackson W, Dordai D, Rudek MA, Semenza GL. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy. The Journal of Clinical Investigation. 132. PMID 35499076 DOI: 10.1172/JCI156774  0.381
2020 Datan E, Salman S. Autophagic cell death in viral infection: Do TAM receptors play a role? International Review of Cell and Molecular Biology. 357: 123-168. PMID 33234242 DOI: 10.1016/bs.ircmb.2020.10.001  0.451
2020 Tong L, Zhao Q, Datan E, Lin GQ, Minn I, Pomper MG, Yu B, Romo D, He QL, Liu JO. Triptolide: reflections on two decades of research and prospects for the future. Natural Product Reports. PMID 33146205 DOI: 10.1039/d0np00054j  0.723
2020 Datan E, Minn I, Xu P, He QL, Ahn HH, Yu B, Pomper MG, Liu JO. A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia. Iscience. 23: 101536. PMID 33083765 DOI: 10.1016/J.Isci.2020.101536  0.753
2019 Episcopio D, Aminov S, Benjamin S, Germain G, Datan E, Landazuri J, Lockshin RA, Zakeri Z. Atorvastatin restricts the ability of influenza virus to generate lipid droplets and severely suppresses the replication of the virus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900428RR. PMID 31125254 DOI: 10.1096/Fj.201900428Rr  0.517
2016 He QL, Minn I, Wang Q, Xu P, Head SA, Datan E, Yu B, Pomper MG, Liu JO. Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation. Angewandte Chemie (International Ed. in English). PMID 27574181 DOI: 10.1002/Anie.201606121  0.727
2016 Datan E, Roy SG, Germain G, Zali N, McLean JE, Golshan G, Harbajan S, Lockshin RA, Zakeri Z. Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation. Cell Death & Disease. 7: e2127. PMID 26938301 DOI: 10.1038/Cddis.2015.409  0.825
2014 Ghosh Roy S, Sadigh B, Datan E, Lockshin RA, Zakeri Z. Regulation of cell survival and death during Flavivirus infections. World Journal of Biological Chemistry. 5: 93-105. PMID 24921001 DOI: 10.4331/Wjbc.V5.I2.93  0.814
2014 Datan E, Shirazian A, Benjamin S, Matassov D, Tinari A, Malorni W, Lockshin RA, Garcia-Sastre A, Zakeri Z. MTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection Virology. 452: 175-190. PMID 24606695 DOI: 10.1016/J.Virol.2014.01.008  0.679
2011 McLean JE, Wudzinska A, Datan E, Quaglino D, Zakeri Z. Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication. The Journal of Biological Chemistry. 286: 22147-59. PMID 21511946 DOI: 10.1074/Jbc.M110.192500  0.797
2009 McLean JE, Datan E, Matassov D, Zakeri ZF. Lack of Bax prevents influenza A virus-induced apoptosis and causes diminished viral replication. Journal of Virology. 83: 8233-46. PMID 19494020 DOI: 10.1128/Jvi.02672-08  0.82
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