Franklin Hutchinson - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
biological effects of radiation
Website:
http://www.yale.edu/opa/arc-ybc/ybc/v26.n12.obit.html

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2003 McNULTY WP, HUTCHINSON F. Deuteron inactivation of dry bovine serum albumin. Archives of Biochemistry and Biophysics. 50: 92-103. PMID 13159304 DOI: 10.1016/0003-9861(54)90012-0  0.324
1997 Hutchinson F, Donnellan JE. A mutation spectra database for bacterial and mammalian genes. Nucleic Acids Research. 25: 192-5. PMID 9016534 DOI: 10.1093/Nar/25.1.192  0.317
1996 Hutchinson F, Donnellan JE. A general database for DNA sequence changes induced by mutagenesis of several bacterial and mammalian genes. Nucleic Acids Research. 24: 172-6. PMID 8594573 DOI: 10.1093/Nar/24.1.172  0.368
1995 Hutchinson F. Analysis of deletions induced in the genome of mammalian cells by ionizing radiation. Journal of Molecular Biology. 254: 372-80. PMID 7490756 DOI: 10.1006/Jmbi.1995.0624  0.417
1994 Hutchinson F. Induction of tandem-base change mutations. Mutation Research. 309: 11-5. PMID 7519728 DOI: 10.1016/0027-5107(94)90037-X  0.408
1993 Hutchinson F. Induction of large DNA deletions by persistent nicks: a new hypothesis. Mutation Research. 299: 211-8. PMID 7683088 DOI: 10.1016/0165-1218(93)90097-W  0.486
1992 Hutchinson F. Published data on mutagenesis by ionizing radiation of plasmids in solution probably reflect in part the specificity of adventitious transition metal ions complexed to the DNA. Mutation Research. 281: 261-6. PMID 1373220 DOI: 10.1016/0165-7992(92)90019-E  0.41
1991 Sockett H, Romac S, Hutchinson F. Mutagenic specificity of N-methyl-N'-nitro-N-nitrosoguanidine in the gpt gene on a chromosome of Chinese hamster ovary cells and of Escherichia coli cells. Molecular & General Genetics : Mgg. 227: 252-9. PMID 2062306 DOI: 10.1007/Bf00259678  0.365
1991 Sockett H, Romac S, Hutchinson F. DNA sequence changes in mutations induced by ultraviolet light in the gpt gene on the chromosome of Escherichia coli uvr+ and urvA cells. Molecular & General Genetics : Mgg. 230: 295-301. PMID 1836051 DOI: 10.1007/Bf00290680  0.381
1991 Raha M, Hutchinson F. Deletions induced by gamma rays in the genome of Escherichia coli. Journal of Molecular Biology. 220: 193-8. PMID 1830341 DOI: 10.1016/0022-2836(91)90001-M  0.435
1989 Romac S, Leong P, Sockett H, Hutchinson F. DNA base sequence changes induced by ultraviolet light mutagenesis of a gene on a chromosome in Chinese hamster ovary cells. Journal of Molecular Biology. 209: 195-204. PMID 2685319 DOI: 10.1016/0022-2836(89)90272-6  0.411
1989 Hutchinson F. On the measurement of DNA double-strand breaks by neutral elution. Radiation Research. 120: 182-6. PMID 2678225 DOI: 10.2307/3577646  0.462
1989 Hutchinson F. Use of data from bacteria to interpret data on DNA damage processing in mammalian cells. Mutation Research. 220: 269-78. PMID 2648137 DOI: 10.1016/0165-1110(89)90031-6  0.439
1988 Hutchinson F, Yamamoto K, Stein J, Wood RD. Effect of photoreactivation on mutagenesis of lambda phage by ultraviolet light. Journal of Molecular Biology. 202: 593-601. PMID 2971813 DOI: 10.1016/0022-2836(88)90289-6  0.61
1988 Tindall KR, Stein J, Hutchinson F. Changes in DNA base sequence induced by gamma-ray mutagenesis of lambda phage and prophage. Genetics. 118: 551-60. PMID 2966755  0.308
1987 Reed J, Hutchinson F. Effect of the direction of DNA replication on mutagenesis by N-methyl-N'-nitro-N-nitrosoguanidine in adapted cells of Escherichia coli. Molecular & General Genetics : Mgg. 208: 446-9. PMID 3312948 DOI: 10.1007/Bf00328137  0.358
1987 Wood RD, Hutchinson F. Ultraviolet light-induced mutagenesis in the Escherichia coli chromosome. Sequences of mutants in the cI gene of a lambda lysogen. Journal of Molecular Biology. 193: 637-41. PMID 3302271 DOI: 10.1016/0022-2836(87)90346-9  0.581
1986 Hutchinson F, Wood RD. Mechanisms of mutagenesis of E. coli by ultraviolet light. Basic Life Sciences. 38: 377-83. PMID 2943265 DOI: 10.1007/978-1-4615-9462-8_41  0.536
1985 Hutchinson F. Chemical changes induced in DNA by ionizing radiation. Progress in Nucleic Acid Research and Molecular Biology. 32: 115-54. PMID 3003798 DOI: 10.1016/S0079-6603(08)60347-5  0.384
1985 Skopek TR, Wood RD, Hutchinson F. Sequence specificity of mutagenesis in the cI gene of bacteriophage lambda. Environmental Health Perspectives. 62: 157-61. PMID 2935390 DOI: 10.1289/Ehp.8562157  0.567
1984 Wagner R, Dohet C, Jones M, Doutriaux MP, Hutchinson F, Radman M. Involvement of Escherichia coli mismatch repair in DNA replication and recombination. Cold Spring Harbor Symposia On Quantitative Biology. 49: 611-5. PMID 6397316 DOI: 10.1101/Sqb.1984.049.01.069  0.323
1984 Skopek TR, Hutchinson F. Frameshift mutagenesis of lambda prophage by 9-aminoacridine, proflavin and ICR-191. Molecular & General Genetics : Mgg. 195: 418-23. PMID 6236349 DOI: 10.1007/Bf00341442  0.442
1984 Wood RD, Hutchinson F. Non-targeted mutagenesis of unirradiated lambda phage in Escherichia coli host cells irradiated with ultraviolet light. Journal of Molecular Biology. 173: 293-305. PMID 6230459 DOI: 10.1016/0022-2836(84)90122-0  0.583
1984 Wood RD, Skopek TR, Hutchinson F. Changes in DNA base sequence induced by targeted mutagenesis of lambda phage by ultraviolet light. Journal of Molecular Biology. 173: 273-91. PMID 6230458 DOI: 10.1016/0022-2836(84)90121-9  0.571
1984 Yamamoto K, Hutchinson F. The effect of bleomycin on DNA in Escherichia coli K12 cells. Chemico-Biological Interactions. 51: 233-46. PMID 6205777 DOI: 10.1016/0009-2797(84)90032-2  0.458
1982 Skopek TR, Hutchinson F. DNA base sequence changes induced by bromouracil mutagenesis of lambda phage. Journal of Molecular Biology. 159: 19-33. PMID 6215499 DOI: 10.1016/0022-2836(82)90029-8  0.373
1981 Krasin F, Hutchinson F. Repair of DNA double-strand breaks in Escherichia coli cells requires synthesis of proteins that can be induced by UV light. Proceedings of the National Academy of Sciences of the United States of America. 78: 3450-3. PMID 7022449 DOI: 10.1073/Pnas.78.6.3450  0.455
1981 Hutchinson F, Stein J. Mutagenesis of lambda phage: weigle mutagenesis is induced by coincident lesions in the double helical DNA of the host cell genome. Molecular & General Genetics : Mgg. 181: 458-63. PMID 6455586 DOI: 10.1007/Bf00428736  0.437
1980 Hutchinson F, Stein J. Mutagenesis of ultraviolet-irradiated lambda phage by host cell irradiation: induction of Weigle mutagenesis is not an all-or-none process. Molecular & General Genetics : Mgg. 177: 207-11. PMID 6445034 DOI: 10.1007/Bf00267431  0.387
1979 Yamamoto K, Hutchinson F. Response to bleomycin of Escherichia coli mutants deficient in DNA repair. The Journal of Antibiotics. 32: 1181-5. PMID 93597 DOI: 10.7164/Antibiotics.32.1181  0.353
1978 Krasin F, Hutchinson F. Strand breaks and alkali-labile bonds induced by ultraviolet light in DNA with 5-bromouracil in vivo. Biophysical Journal. 24: 657-64. PMID 367462 DOI: 10.1016/S0006-3495(78)85411-3  0.362
1978 Krasin F, Hutchinson F. Double-strand breaks from single photochemical events in DNA containing 5-bromouracil. Biophysical Journal. 24: 645-56. PMID 367461 DOI: 10.1016/S0006-3495(78)85410-1  0.354
1978 Povirk LF, Köhnlein W, Hutchinson F. Specificity of DNA base release by bleomycin. Biochimica Et Biophysica Acta. 521: 126-33. PMID 82451 DOI: 10.1016/0005-2787(78)90255-1  0.578
1978 Hutchinson F. Workshop Summary: Dna Strand Break Repair In Eukaryotes Dna Repair Mechanisms. 457-463. DOI: 10.1016/B978-0-12-322650-1.50089-8  0.445
1977 Krasin F, Hutchinson F. Repair of DNA double-strand breaks in Escherichia coli, which requires recA function and the presence of a duplicate genome. Journal of Molecular Biology. 116: 81-98. PMID 338918 DOI: 10.1016/0022-2836(77)90120-6  0.452
1977 Hutchinson F, Stein J. Mutagenesis of lambda phage: 5-bromouracil and hydroxylamine. Molecular & General Genetics : Mgg. 152: 29-36. PMID 325384 DOI: 10.1007/Bf00264936  0.356
1977 Povirk LF, Wübter W, Köhnlein W, Hutchinson F. DNA double-strand breaks and alkali-labile bonds produced by bleomycin. Nucleic Acids Research. 4: 3573-80. PMID 73164 DOI: 10.1093/Nar/4.10.3573  0.63
1976 Köhnlein W, Hutchinson F. A four-stranded DNA from Bacillus subtilis which may be an intermediate in genetic recombination. Molecular & General Genetics : Mgg. 144: 323-31. PMID 818506 DOI: 10.1007/Bf00341731  0.4
1976 Hutchinson F, Krasin F. Dependence of the sedimentation of high molecular weight DNA on centrifuge speed. Biophysical Chemistry. 6: 23-9. PMID 797403 DOI: 10.1016/0301-4622(76)80058-0  0.371
1976 Krasin F, Person S, Ley RD, Hutchinson F. DNA crosslinks, single-strand breaks and effects on bacteriophage T4 survival from tritium decay of (2-3H)adenine, (8-3H)adenine and (8-3H)guanine. Journal of Molecular Biology. 101: 197-209. PMID 772217 DOI: 10.1016/0022-2836(76)90372-7  0.398
1973 Hutchinson F. The lesions produced by ultraviolet light in DNA containing 5-bromouracil. Quarterly Reviews of Biophysics. 6: 201-46. PMID 4579676 DOI: 10.1017/S0033583500001141  0.374
1973 Levin D, Hutchinson F. Relation between single-strand DNA mass and sedimentation distance in alkaline sucrose gradients. Journal of Molecular Biology. 75: 495-502. PMID 4199038 DOI: 10.1016/0022-2836(73)90456-7  0.402
1973 Hariharan PV, Hutchinson F. Neutral sucrose gradient sedimentation of very large DNA from Bacillus subtilis. II. Double-strand breaks formed by gamma ray irradiation of the cells. Journal of Molecular Biology. 75: 479-94. PMID 4199037 DOI: 10.1016/0022-2836(73)90455-5  0.45
1973 Levin D, Hutchinson F. Neutral sucrose sedimentation of very large DNA from Bacillus subtilis. I. Effect of random double-strand breaks and centrifuge speed on sedimentation Journal of Molecular Biology. 75: 455-478. PMID 4199036 DOI: 10.1016/0022-2836(73)90454-3  0.425
1971 Thorsett GO, Hutchinson F. Effects on bacterial transformation of single-strand breaks in DNA produced by deoxyribonuclease I and γ rays Bba Section Nucleic Acids and Protein Synthesis. 238: 67-74. PMID 4397000 DOI: 10.1016/0005-2787(71)90010-4  0.408
1970 Hutchinson F, Hales HB. Mechanism of the sensitization of bacterial transforming DNA to ultraviolet light by the incorporation of 5-bromouracil Journal of Molecular Biology. 50: 59-69. PMID 4990077 DOI: 10.1016/0022-2836(70)90103-8  0.444
1969 Köhnlein W, Hutchinson F. ESR-studies of normal and 5-bromouracil-substituted DNA of Bacillus subtilis after irradiation with ultraviolet light Radiation Research. 39: 745-757. PMID 4308875 DOI: 10.2307/3572950  0.428
1967 Ray DK, Hutchinson F. Inactivation of dry ribonuclease by ionizing radiation. II. A suggested mechanism Bba - Protein Structure. 147: 357-368. PMID 5624044 DOI: 10.1016/0005-2795(67)90414-X  0.352
1967 Ray DK, Hutchinson F. Inactivation of dry ribonuclease by ionizing radiation. I. Search for the breakage of sulfur bridges Bba - Protein Structure. 147: 347-356. PMID 5624043 DOI: 10.1016/0005-2795(67)90413-8  0.309
1967 Scholes CP, Hutchinson F, Hales HB. Ultraviolet-induced damage to DNA independent of molecular weight Journal of Molecular Biology. 24: 471-474. DOI: 10.1016/0022-2836(67)90232-X  0.383
1966 Köhnlein W, Thorsett G, Hutchinson F. A bacterial DNA with a difference in thymine content in the complementary strands Bba Section Nucleic Acids and Protein Synthesis. 119: 195-197. PMID 4960037 DOI: 10.1016/0005-2787(66)90051-7  0.423
1965 Tanooka H, Hutchinson F. Modifications of the Inactivation by Ionizing Radiations of the Transforming Activity of DNA in Spores and Dry Cells Radiation Research. 24: 43-56. DOI: 10.2307/3571715  0.424
1961 HUTCHINSON F. Sulfhydryl groups and the oxygen effect on irradiated dilute solutions of enzymes and nucleic acids Radiation Research. 14: 721-731. PMID 13717054 DOI: 10.2307/3571013  0.388
1960 Ray DK, Hutchinson F, Morowitz HJ. A connexion between S - S bond breakage and inactivation by radiation of a dry enzyme Nature. 186: 312-313. PMID 14436616 DOI: 10.1038/186312B0  0.485
1960 HUTCHINSON F. Modifying factors in the inactivation of biological macromolecules Radiation Research. 49-64. PMID 14405631 DOI: 10.2307/3583587  0.304
1958 Braams R, Hutchinson F, Ray D. Changes in the sensitivity of enzymes in the dry state to radiation Nature. 182: 1506. DOI: 10.1038/1821506A0  0.303
1957 HUTCHINSON F. The distance that a radical formed by ionizing radiation can diffuse in a yeast cell Radiation Research. 7: 473-483. PMID 13485388 DOI: 10.2307/3570395  0.316
1957 Hutchinson F, Morowitz H, Kempner E. Evidence concerning the size of amino acid incorporation structures in Escherichia coli Science. 126: 310. PMID 13454824 DOI: 10.1126/Science.126.3268.310  0.434
1957 Hutchinson F, Preston A, Vogel B. Radiation Sensitivity of Enzymes in Wet and in Dry Yeast Cells Radiation Research. 7: 465. DOI: 10.2307/3570394  0.357
1955 Pollard E, Guild W, Hutchinson F, Setlow R. The Direct Action of Ionizing Radiation on Enzymes and Antigens Progress in Biophysics and Biophysical Chemistry. 5: 72-108. DOI: 10.1016/S0096-4174(18)30084-2  0.52
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