| Year |
Citation |
Score |
| 2024 |
Murawska GM, Armando A, Dennis EA. Lipidomics of Phospholipase A Reveals Exquisite Specificity in Macrophages. Journal of Lipid Research. 100571. PMID 38795860 DOI: 10.1016/j.jlr.2024.100571 |
0.324 |
|
| 2020 |
Venn-Watson S, Lumpkin R, Dennis EA. Efficacy of dietary odd-chain saturated fatty acid pentadecanoic acid parallels broad associated health benefits in humans: could it be essential? Scientific Reports. 10: 8161. PMID 32424181 DOI: 10.1038/S41598-020-64960-Y |
0.308 |
|
| 2020 |
Mouchlis VD, Mu C, Hammons R, Dennis EA. Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A inhibitors. Advances in Biological Regulation. 100719. PMID 32199750 DOI: 10.1016/J.Jbior.2020.100719 |
0.335 |
|
| 2020 |
Dennis EA. Enzyme Hydrophobic Sites and Allosteric Membrane Interactions Regulate Signaling and Mediators of Inflammation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00199 |
0.32 |
|
| 2019 |
Mouchlis VD, Dennis EA. Phospholipase A catalysis and lipid mediator lipidomics. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1864: 766-771. PMID 30905345 DOI: 10.1016/J.Bbalip.2018.08.010 |
0.431 |
|
| 2019 |
Decl Egraveves AE, Mathew AV, Armando AM, Han X, Dennis EA, Quehenberger O, Sharma K. AMP-activated protein kinase activation ameliorates eicosanoid dysregulation in high-fat-induced kidney disease in mice. Journal of Lipid Research. PMID 30862696 DOI: 10.1194/Jlr.M088690 |
0.32 |
|
| 2019 |
Dedaki C, Kokotou MG, Mouchlis VD, Limnios D, Lei X, Mu CT, Ramanadham S, Magrioti V, Dennis EA, Kokotos G. β-Lactones: A Novel Class of Ca2+-Independent Phospholipase A2 (Group VIA iPLA2) Inhibitors with Ability to Inhibit β-Cell Apoptosis. Journal of Medicinal Chemistry. PMID 30798607 DOI: 10.1021/Acs.Jmedchem.8B01216 |
0.35 |
|
| 2019 |
Feuerherm AJ, Dennis EA, Johansen B. Cytosolic group IVA phospholipase A2 inhibitors, AVX001 and AVX002, ameliorate collagen-induced arthritis. Arthritis Research & Therapy. 21: 29. PMID 30665457 DOI: 10.1186/S13075-018-1794-6 |
0.365 |
|
| 2019 |
Mouchlis VD, Armando A, Dennis EA. Substrate specific inhibition constants for phospholipase A2 acting on unique phospholipid substrates in mixed micelles and membranes using lipidomics. Journal of Medicinal Chemistry. PMID 30615445 DOI: 10.1021/Acs.Jmedchem.8B01568 |
0.398 |
|
| 2018 |
Quehenberger O, Dahlberg-Wright S, Jiang J, Armando AM, Dennis EA. Quantitative determination of esterified eicosanoids and related oxygenated metabolites after base hydrolysis. Journal of Lipid Research. PMID 30323111 DOI: 10.1194/Jlr.D089516 |
0.36 |
|
| 2018 |
Gregus AM, Buczynski MW, Dumlao DS, Norris PC, Rai G, Simeonov A, Maloney DJ, Jadhav A, Xu Q, Wei SC, Fitzsimmons BL, Dennis EA, Yaksh TL. Inhibition of Spinal 15-LOX-1 Attenuates TLR4-Dependent, NSAID-Unresponsive Hyperalgesia in Male Rats. Pain. PMID 30130298 DOI: 10.1097/J.Pain.0000000000001373 |
0.646 |
|
| 2018 |
Mouchlis VD, Chen Y, McCammon JA, Dennis EA. Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity. Journal of the American Chemical Society. PMID 29342349 DOI: 10.1021/Jacs.7B12045 |
0.414 |
|
| 2018 |
Mouchlis VD, McCammon JA, Dennis EA. Allosteric Regulation by Membranes Controls Specificity of Lipolytic Enzymes through Recruitment of Unique Hydrophobic Binding Pockets Biophysical Journal. 114: 66a. DOI: 10.1016/J.Bpj.2017.11.409 |
0.302 |
|
| 2017 |
Vasquez AM, Mouchlis VD, Dennis EA. Review of four major distinct types of human phospholipase A2. Advances in Biological Regulation. PMID 29248300 DOI: 10.1016/J.Jbior.2017.10.009 |
0.423 |
|
| 2017 |
Navratil AR, Shchepinov MS, Dennis EA. Lipidomics Reveals Dramatic Physiological Kinetic Isotope Effects during the Enzymatic Oxygenation of Polyunsaturated Fatty Acids Ex Vivo. Journal of the American Chemical Society. PMID 29206462 DOI: 10.1021/Jacs.7B09493 |
0.35 |
|
| 2017 |
Kokotou MG, Galiatsatou G, Magrioti V, Koutoulogenis G, Barbayianni E, Limnios D, Mouchlis VD, Satpathy B, Navratil A, Dennis EA, Kokotos G. 2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2. Scientific Reports. 7: 7025. PMID 28765606 DOI: 10.1038/S41598-017-07330-5 |
0.428 |
|
| 2016 |
Smyrniotou A, Kokotou MG, Mouchlis VD, Barbayianni E, Kokotos G, Dennis EA, Constantinou-Kokotou V. 2-Oxoamides based on dipeptides as selective calcium-independent phospholipase A2 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28034646 DOI: 10.1016/J.Bmc.2016.12.007 |
0.367 |
|
| 2016 |
Dennis EA. Lipid Cell Signaling, Enzymes, LIPID MAPS, and Mediators of Inflammation. The Journal of Biological Chemistry. PMID 27555328 DOI: 10.1074/Jbc.X116.723791 |
0.391 |
|
| 2016 |
Antonopoulou G, Magrioti V, Kokotou MG, Nikolaou A, Barbayianni E, Mouchlis VD, Dennis EA, Kokotos G. 2-Oxoamide inhibitors of cytosolic group IVA phospholipase A2 with reduced lipophilicity. Bioorganic & Medicinal Chemistry. PMID 27522578 DOI: 10.1016/J.Bmc.2016.07.057 |
0.397 |
|
| 2016 |
Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA. Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. Bioorganic & Medicinal Chemistry. 24: 4801-4811. PMID 27320659 DOI: 10.1016/J.Bmc.2016.05.009 |
0.378 |
|
| 2016 |
Mouchlis VD, Limnios D, Kokotou MG, Barbayianni E, Kokotos G, McCammon JA, Dennis EA. Development of Potent and Selective Inhibitors for Group VIA Calcium-Independent Phospholipase A2 Guided by Molecular Dynamics and Structure-Activity Relationships. Journal of Medicinal Chemistry. 59: 4403-14. PMID 27087127 DOI: 10.1021/Acs.Jmedchem.6B00377 |
0.387 |
|
| 2016 |
Gupta S, Kihara Y, Maurya MR, Norris PC, Dennis EA, Subramaniam S. Computational Modeling of Competitive Metabolism Between ω3- and ω6 Polyunsaturated Fatty Acids in Inflammatory Macrophages. The Journal of Physical Chemistry. B. PMID 27063350 DOI: 10.1021/Acs.Jpcb.6B02036 |
0.671 |
|
| 2015 |
Mouchlis VD, Dennis EA. Membrane and inhibitor interactions of intracellular phospholipases A2. Advances in Biological Regulation. PMID 26774606 DOI: 10.1016/J.Jbior.2015.11.011 |
0.417 |
|
| 2015 |
Dennis EA, Norris PC. Eicosanoid storm in infection and inflammation. Nature Reviews. Immunology. PMID 26139350 DOI: 10.1038/Nri3859 |
0.658 |
|
| 2015 |
Mouchlis VD, Bucher D, McCammon JA, Dennis EA. Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates. Proceedings of the National Academy of Sciences of the United States of America. 112: E516-25. PMID 25624474 DOI: 10.1073/Pnas.1424651112 |
0.355 |
|
| 2015 |
Astarita G, Kendall AC, Dennis EA, Nicolaou A. Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids. Biochimica Et Biophysica Acta. 1851: 456-468. PMID 25486530 DOI: 10.1016/J.Bbalip.2014.11.012 |
0.325 |
|
| 2015 |
Dennis EA, Norris PC. Erratum: Eicosanoid storm in infection and inflammation Nature Reviews Immunology. 15: 724-724. DOI: 10.1038/Nri3928 |
0.606 |
|
| 2014 |
Baker PR, Armando AM, Campbell JL, Quehenberger O, Dennis EA. Three-dimensional enhanced lipidomics analysis combining UPLC, differential ion mobility spectrometry, and mass spectrometric separation strategies. Journal of Lipid Research. 55: 2432-42. PMID 25225680 DOI: 10.1194/Jlr.D051581 |
0.323 |
|
| 2014 |
Kokotos G, Feuerherm AJ, Barbayianni E, Shah I, Sæther M, Magrioti V, Nguyen T, Constantinou-Kokotou V, Dennis EA, Johansen B. Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo. Journal of Medicinal Chemistry. 57: 7523-35. PMID 25152071 DOI: 10.1021/Jm500192S |
0.394 |
|
| 2014 |
Norris PC, Gosselin D, Reichart D, Glass CK, Dennis EA. Phospholipase A2 regulates eicosanoid class switching during inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 12746-51. PMID 25139986 DOI: 10.1073/Pnas.1404372111 |
0.714 |
|
| 2014 |
Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular Cancer Research : McR. 12: 1677-88. PMID 25063587 DOI: 10.1158/1541-7786.Mcr-14-0397-T |
0.627 |
|
| 2014 |
Kihara Y, Gupta S, Maurya MR, Armando A, Shah I, Quehenberger O, Glass CK, Dennis EA, Subramaniam S. Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases. Biophysical Journal. 106: 966-75. PMID 24559999 DOI: 10.1016/J.Bpj.2014.01.015 |
0.381 |
|
| 2014 |
Norris PC, Dennis EA. A lipidomic perspective on inflammatory macrophage eicosanoid signaling. Advances in Biological Regulation. 54: 99-110. PMID 24113376 DOI: 10.1016/J.Jbior.2013.09.009 |
0.686 |
|
| 2014 |
Maurya MR, Gupta S, Li X, Fahy E, Dinasarapu AR, Sud M, Brown HA, Glass CK, Murphy RC, Russell DW, Dennis EA, Subramaniam S. Erratum: Analysis of infl ammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages (J. Lipid Res. (2013) 54 (2525-2542) Journal of Lipid Research. 55. DOI: 10.1194/Jlr.M040212Err |
0.303 |
|
| 2014 |
Bucher D, Mouchlis VD, Dennis EA, McCammon JA. Modeling and Inhibitor Design of Ca(2+)-Independent Phospholipase A2 Biophysical Journal. 106: 38a. DOI: 10.1016/J.Bpj.2013.11.283 |
0.387 |
|
| 2013 |
Choi SH, Yin H, Ravandi A, Armando A, Dumlao D, Kim J, Almazan F, Taylor AM, McNamara CA, Tsimikas S, Dennis EA, Witztum JL, Miller YI. Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages. Plos One. 8: e83145. PMID 24376657 DOI: 10.1371/Journal.Pone.0083145 |
0.379 |
|
| 2013 |
Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, ... ... Dennis EA, et al. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. The Journal of Biological Chemistry. 288: 35812-23. PMID 24189069 DOI: 10.1074/Jbc.M113.519637 |
0.569 |
|
| 2013 |
Li P, Spann NJ, Kaikkonen MU, Lu M, Oh da Y, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, et al. NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell. 155: 200-14. PMID 24074869 DOI: 10.1016/J.Cell.2013.08.054 |
0.343 |
|
| 2013 |
Magrioti V, Nikolaou A, Smyrniotou A, Shah I, Constantinou-Kokotou V, Dennis EA, Kokotos G. New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2. Bioorganic & Medicinal Chemistry. 21: 5823-9. PMID 23916152 DOI: 10.1016/J.Bmc.2013.07.010 |
0.351 |
|
| 2013 |
Tam VC, Quehenberger O, Oshansky CM, Suen R, Armando AM, Treuting PM, Thomas PG, Dennis EA, Aderem A. Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation. Cell. 154: 213-27. PMID 23827684 DOI: 10.1016/J.Cell.2013.05.052 |
0.308 |
|
| 2013 |
Maurya MR, Gupta S, Li X, Fahy E, Dinasarapu AR, Sud M, Brown HA, Glass CK, Murphy RC, Russell DW, Dennis EA, Subramaniam S. Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. Journal of Lipid Research. 54: 2525-42. PMID 23776196 DOI: 10.1194/Jlr.M040212 |
0.348 |
|
| 2013 |
Hsu YH, Dumlao DS, Cao J, Dennis EA. Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry. Plos One. 8: e59267. PMID 23533611 DOI: 10.1371/Journal.Pone.0059267 |
0.383 |
|
| 2013 |
Gregus AM, Dumlao DS, Wei SC, Norris PC, Catella LC, Meyerstein FG, Buczynski MW, Steinauer JJ, Fitzsimmons BL, Yaksh TL, Dennis EA. Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1939-49. PMID 23382512 DOI: 10.1096/Fj.12-217414 |
0.679 |
|
| 2013 |
Hsu YH, Bucher D, Cao J, Li S, Yang SW, Kokotos G, Woods VL, McCammon JA, Dennis EA. Fluoroketone inhibition of Ca(2+)-independent phospholipase A2 through binding pocket association defined by hydrogen/deuterium exchange and molecular dynamics. Journal of the American Chemical Society. 135: 1330-7. PMID 23256506 DOI: 10.1021/Ja306490G |
0.323 |
|
| 2013 |
Cao J, Burke JE, Dennis EA. Using hydrogen/deuterium exchange mass spectrometry to define the specific interactions of the phospholipase A2 superfamily with lipid substrates, inhibitors, and membranes. The Journal of Biological Chemistry. 288: 1806-13. PMID 23209293 DOI: 10.1074/Jbc.R112.421909 |
0.363 |
|
| 2013 |
Cao J, Hsu YH, Li S, Woods VL, Dennis EA. Structural basis of specific interactions of Lp-PLA2 with HDL revealed by hydrogen deuterium exchange mass spectrometry. Journal of Lipid Research. 54: 127-33. PMID 23089916 DOI: 10.1194/Jlr.M030221 |
0.329 |
|
| 2012 |
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, ... ... Dennis EA, et al. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 151: 138-52. PMID 23021221 DOI: 10.1016/J.Cell.2012.06.054 |
0.599 |
|
| 2012 |
Pang XY, Cao J, Addington L, Lovell S, Battaile KP, Zhang N, Rao JL, Dennis EA, Moise AR. Structure/function relationships of adipose phospholipase A2 containing a cys-his-his catalytic triad. The Journal of Biological Chemistry. 287: 35260-74. PMID 22923616 DOI: 10.1074/Jbc.M112.398859 |
0.347 |
|
| 2012 |
Dumlao DS, Cunningham AM, Wax LE, Norris PC, Hanks JH, Halpin R, Lett KM, Blaho VA, Mitchell WJ, Fritsche KL, Dennis EA, Brown CR. Dietary fish oil substitution alters the eicosanoid profile in ankle joints of mice during Lyme infection. The Journal of Nutrition. 142: 1582-9. PMID 22695969 DOI: 10.3945/Jn.112.157883 |
0.634 |
|
| 2012 |
Norris PC, Dennis EA. Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 8517-22. PMID 22586114 DOI: 10.1073/Pnas.1200189109 |
0.697 |
|
| 2012 |
Gregus AM, Doolen S, Dumlao DS, Buczynski MW, Takasusuki T, Fitzsimmons BL, Hua XY, Taylor BK, Dennis EA, Yaksh TL. Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 6721-6. PMID 22493235 DOI: 10.1073/Pnas.1110460109 |
0.318 |
|
| 2012 |
Sabidó E, Quehenberger O, Shen Q, Chang CY, Shah I, Armando AM, Andreyev A, Vitek O, Dennis EA, Aebersold R. Targeted proteomics of the eicosanoid biosynthetic pathway completes an integrated genomics-proteomics-metabolomics picture of cellular metabolism. Molecular & Cellular Proteomics : McP. 11: M111.014746. PMID 22361236 DOI: 10.1074/Mcp.M111.014746 |
0.36 |
|
| 2012 |
Harkewicz R, Du H, Tong Z, Alkuraya H, Bedell M, Sun W, Wang X, Hsu YH, Esteve-Rudd J, Hughes G, Su Z, Zhang M, Lopes VS, Molday RS, Williams DS, ... Dennis EA, et al. Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function. The Journal of Biological Chemistry. 287: 11469-80. PMID 22199362 DOI: 10.1074/Jbc.M111.256073 |
0.313 |
|
| 2012 |
Mouchlis VD, Michopoulou V, Constantinou-Kokotou V, Mavromoustakos T, Dennis EA, Kokotos G. Binding conformation of 2-oxoamide inhibitors to group IVA cytosolic phospholipase A2 determined by molecular docking combined with molecular dynamics. Journal of Chemical Information and Modeling. 52: 243-54. PMID 22196172 DOI: 10.1021/Ci2005093 |
0.331 |
|
| 2012 |
Dennis EA, Plückthun A. Phosphorus-31 NMR of Phospholipids in Micelles Phosphorous-31 Nmr: Principles and Applications. 423-446. DOI: 10.1016/B978-0-08-091841-9.50019-9 |
0.364 |
|
| 2011 |
Dennis EA, Cao J, Hsu YH, Magrioti V, Kokotos G. Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention. Chemical Reviews. 111: 6130-85. PMID 21910409 DOI: 10.1021/Cr200085W |
0.417 |
|
| 2011 |
López-Vales R, Ghasemlou N, Redensek A, Kerr BJ, Barbayianni E, Antonopoulou G, Baskakis C, Rathore KI, Constantinou-Kokotou V, Stephens D, Shimizu T, Dennis EA, Kokotos G, David S. Phospholipase A2 superfamily members play divergent roles after spinal cord injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4240-52. PMID 21868473 DOI: 10.1096/Fj.11-183186 |
0.385 |
|
| 2011 |
Quehenberger O, Armando AM, Dennis EA. High sensitivity quantitative lipidomics analysis of fatty acids in biological samples by gas chromatography-mass spectrometry. Biochimica Et Biophysica Acta. 1811: 648-56. PMID 21787881 DOI: 10.1016/J.Bbalip.2011.07.006 |
0.338 |
|
| 2011 |
Dumlao DS, Buczynski MW, Norris PC, Harkewicz R, Dennis EA. High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines. Biochimica Et Biophysica Acta. 1811: 724-36. PMID 21689782 DOI: 10.1016/J.Bbalip.2011.06.005 |
0.676 |
|
| 2011 |
Norris PC, Reichart D, Dumlao DS, Glass CK, Dennis EA. Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype. Journal of Leukocyte Biology. 90: 563-74. PMID 21653236 DOI: 10.1189/Jlb.0311153 |
0.687 |
|
| 2011 |
Cao J, Hsu YH, Li S, Woods VL, Dennis EA. Lipoprotein-associated phospholipase A(2) interacts with phospholipid vesicles via a surface-disposed hydrophobic α-helix. Biochemistry. 50: 5314-21. PMID 21553808 DOI: 10.1021/Bi101916W |
0.369 |
|
| 2010 |
Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CR, et al. A mouse macrophage lipidome. The Journal of Biological Chemistry. 285: 39976-85. PMID 20923771 DOI: 10.1074/Jbc.M110.182915 |
0.608 |
|
| 2010 |
Fang L, Harkewicz R, Hartvigsen K, Wiesner P, Choi SH, Almazan F, Pattison J, Deer E, Sayaphupha T, Dennis EA, Witztum JL, Tsimikas S, Miller YI. Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation. The Journal of Biological Chemistry. 285: 32343-51. PMID 20710028 DOI: 10.1074/Jbc.M110.137257 |
0.327 |
|
| 2010 |
Quehenberger O, Armando AM, Brown AH, Milne SB, Myers DS, Merrill AH, Bandyopadhyay S, Jones KN, Kelly S, Shaner RL, Sullards CM, Wang E, Murphy RC, Barkley RM, Leiker TJ, ... ... Dennis EA, et al. Lipidomics reveals a remarkable diversity of lipids in human plasma. Journal of Lipid Research. 51: 3299-305. PMID 20671299 DOI: 10.1194/Jlr.M009449 |
0.736 |
|
| 2010 |
Andreyev AY, Fahy E, Guan Z, Kelly S, Li X, McDonald JG, Milne S, Myers D, Park H, Ryan A, Thompson BM, Wang E, Zhao Y, Brown HA, Merrill AH, ... ... Dennis EA, et al. Subcellular organelle lipidomics in TLR-4-activated macrophages. Journal of Lipid Research. 51: 2785-97. PMID 20574076 DOI: 10.1194/Jlr.M008748 |
0.61 |
|
| 2010 |
Buczynski MW, Svensson CI, Dumlao DS, Fitzsimmons BL, Shim JH, Scherbart TJ, Jacobsen FE, Hua XY, Yaksh TL, Dennis EA. Inflammatory hyperalgesia induces essential bioactive lipid production in the spinal cord. Journal of Neurochemistry. 114: 981-93. PMID 20492349 DOI: 10.1111/J.1471-4159.2010.06815.X |
0.342 |
|
| 2010 |
Kokotos G, Hsu YH, Burke JE, Baskakis C, Kokotos CG, Magrioti V, Dennis EA. Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2. Journal of Medicinal Chemistry. 53: 3602-10. PMID 20369880 DOI: 10.1021/Jm901872V |
0.366 |
|
| 2010 |
Andreyev AY, Shen Z, Guan Z, Ryan A, Fahy E, Subramaniam S, Raetz CR, Briggs S, Dennis EA. Application of proteomic marker ensembles to subcellular organelle identification. Molecular & Cellular Proteomics : McP. 9: 388-402. PMID 19884172 DOI: 10.1074/Mcp.M900432-Mcp200 |
0.55 |
|
| 2010 |
Adamich M, Dennis EA. Phospholipase a(2) action on membrane surfaces: effect of ionic strength, triton x-100, and melittin. Biophysical Journal. 37: 166-8. PMID 19431460 DOI: 10.1016/S0006-3495(82)84653-5 |
0.399 |
|
| 2010 |
Balsinde J, Dennis EA. Role of phospholipase a2 forms in arachidonic acid mobilization and eicosanoid generation Handbook of Cell Signaling, 2/E. 2: 1213-1217. DOI: 10.1016/B978-0-12-374145-5.00149-2 |
0.579 |
|
| 2009 |
Hsu YH, Burke JE, Li S, Woods VL, Dennis EA. Localizing the membrane binding region of Group VIA Ca2+-independent phospholipase A2 using peptide amide hydrogen/deuterium exchange mass spectrometry. The Journal of Biological Chemistry. 284: 23652-61. PMID 19556238 DOI: 10.1074/Jbc.M109.021857 |
0.328 |
|
| 2009 |
Grkovich A, Dennis EA. Phosphatidic acid phosphohydrolase in the regulation of inflammatory signaling. Advances in Enzyme Regulation. 49: 114-20. PMID 19534028 DOI: 10.1016/J.Advenzreg.2009.01.005 |
0.786 |
|
| 2009 |
Gupta S, Maurya MR, Stephens DL, Dennis EA, Subramaniam S. An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis. Biophysical Journal. 96: 4542-51. PMID 19486676 DOI: 10.1016/J.Bpj.2009.03.011 |
0.345 |
|
| 2009 |
Burke JE, Babakhani A, Gorfe AA, Kokotos G, Li S, Woods VL, McCammon JA, Dennis EA. Location of inhibitors bound to group IVA phospholipase A2 determined by molecular dynamics and deuterium exchange mass spectrometry. Journal of the American Chemical Society. 131: 8083-91. PMID 19459633 DOI: 10.1021/Ja900098Y |
0.323 |
|
| 2009 |
Barbayianni E, Stephens D, Grkovich A, Magrioti V, Hsu YH, Dolatzas P, Kalogiannidis D, Dennis EA, Kokotos G. 2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides. Bioorganic & Medicinal Chemistry. 17: 4833-43. PMID 19443224 DOI: 10.1016/j.bmc.2009.03.069 |
0.809 |
|
| 2009 |
Dennis EA, Witztum JL. Fifty years of research on lipids. Journal of Lipid Research. 50: S1. PMID 19346336 DOI: 10.1194/Jlr.Suppeditorial-50/4-Jlr |
0.316 |
|
| 2009 |
Buczynski MW, Dumlao DS, Dennis EA. Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology. Journal of Lipid Research. 50: 1015-38. PMID 19244215 DOI: 10.1194/Jlr.R900004-Jlr200 |
0.303 |
|
| 2009 |
Grkovich A, Armando A, Quehenberger O, Dennis EA. TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent. Biochimica Et Biophysica Acta. 1791: 975-82. PMID 19230851 DOI: 10.1016/J.Bbalip.2009.02.002 |
0.812 |
|
| 2009 |
Kalyvas A, Baskakis C, Magrioti V, Constantinou-Kokotou V, Stephens D, López-Vales R, Lu JQ, Yong VW, Dennis EA, Kokotos G, David S. Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis. Brain : a Journal of Neurology. 132: 1221-35. PMID 19218359 DOI: 10.1093/Brain/Awp002 |
0.348 |
|
| 2009 |
Fahy E, Subramaniam S, Murphy RC, Nishijima M, Raetz CR, Shimizu T, Spener F, van Meer G, Wakelam MJ, Dennis EA. Update of the LIPID MAPS comprehensive classification system for lipids. Journal of Lipid Research. 50: S9-14. PMID 19098281 DOI: 10.1194/Jlr.R800095-Jlr200 |
0.538 |
|
| 2009 |
Burke JE, Dennis EA. Phospholipase A2 structure/function, mechanism, and signaling. Journal of Lipid Research. 50: S237-42. PMID 19011112 DOI: 10.1194/Jlr.R800033-Jlr200 |
0.416 |
|
| 2009 |
Burke JE, Dennis EA. Phospholipase A2 biochemistry. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 23: 49-59. PMID 18931897 DOI: 10.1007/S10557-008-6132-9 |
0.388 |
|
| 2008 |
Baskakis C, Magrioti V, Cotton N, Stephens D, Constantinou-Kokotou V, Dennis EA, Kokotos G. Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes. Journal of Medicinal Chemistry. 51: 8027-37. PMID 19053783 DOI: 10.1021/Jm800649Q |
0.364 |
|
| 2008 |
Quehenberger O, Armando A, Dumlao D, Stephens DL, Dennis EA. Lipidomics analysis of essential fatty acids in macrophages. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 79: 123-9. PMID 18996688 DOI: 10.1016/J.Plefa.2008.09.021 |
0.355 |
|
| 2008 |
Antonopoulou G, Barbayianni E, Magrioti V, Cotton N, Stephens D, Constantinou-Kokotou V, Dennis EA, Kokotos G. Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A(2) enzymes. Bioorganic & Medicinal Chemistry. 16: 10257-69. PMID 18993078 DOI: 10.1016/J.Bmc.2008.10.046 |
0.363 |
|
| 2008 |
Burke JE, Hsu YH, Deems RA, Li S, Woods VL, Dennis EA. A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2. The Journal of Biological Chemistry. 283: 31227-36. PMID 18753135 DOI: 10.1074/Jbc.M804492200 |
0.343 |
|
| 2008 |
Jacobsen FE, Buczynski MW, Dennis EA, Cohen SM. A macrophage cell model for selective metalloproteinase inhibitor design. Chembiochem : a European Journal of Chemical Biology. 9: 2087-95. PMID 18666306 DOI: 10.1002/Cbic.200800148 |
0.301 |
|
| 2008 |
Antonopoulou G, Magrioti V, Stephens D, Constantinou-Kokotou V, Dennis EA, Kokotos G. Synthesis of 2-oxoamides based on sulfonamide analogs of gamma-amino acids and their activity on phospholipase A2. Journal of Peptide Science : An Official Publication of the European Peptide Society. 14: 1111-20. PMID 18618424 DOI: 10.1002/Psc.1048 |
0.395 |
|
| 2008 |
Burke JE, Karbarz MJ, Deems RA, Li S, Woods VL, Dennis EA. Interaction of group IA phospholipase A2 with metal ions and phospholipid vesicles probed with deuterium exchange mass spectrometry. Biochemistry. 47: 6451-9. PMID 18500818 DOI: 10.1021/Bi8000962 |
0.305 |
|
| 2008 |
Harkewicz R, Hartvigsen K, Almazan F, Dennis EA, Witztum JL, Miller YI. Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein. The Journal of Biological Chemistry. 283: 10241-51. PMID 18263582 DOI: 10.1074/Jbc.M709006200 |
0.344 |
|
| 2007 |
Six DA, Barbayianni E, Loukas V, Constantinou-Kokotou V, Hadjipavlou-Litina D, Stephens D, Wong AC, Magrioti V, Moutevelis-Minakakis P, Baker SF, Dennis EA, Kokotos G. Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2. Journal of Medicinal Chemistry. 50: 4222-35. PMID 17672443 DOI: 10.1021/jm0613673 |
0.715 |
|
| 2007 |
Moutevelis-Minakakis P, Neokosmidi A, Filippakou M, Stephens D, Dennis EA, Kokotos G. Synthesis of lipophilic 2-oxoamides based on gamma-aminobutyric and delta-aminovaleric analogues and their activity against phospholipase A2. Journal of Peptide Science : An Official Publication of the European Peptide Society. 13: 634-41. PMID 17631670 DOI: 10.1002/Psc.889 |
0.363 |
|
| 2007 |
Buczynski MW, Stephens DL, Bowers-Gentry RC, Grkovich A, Deems RA, Dennis EA. TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells. The Journal of Biological Chemistry. 282: 22834-47. PMID 17535806 DOI: 10.1074/Jbc.M701831200 |
0.794 |
|
| 2007 |
Harkewicz R, Fahy E, Andreyev A, Dennis EA. Arachidonate-derived dihomoprostaglandin production observed in endotoxin-stimulated macrophage-like cells. The Journal of Biological Chemistry. 282: 2899-910. PMID 17135246 DOI: 10.1074/Jbc.M610067200 |
0.411 |
|
| 2007 |
Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Subramaniam S. LMSD: LIPID MAPS structure database. Nucleic Acids Research. 35: D527-32. PMID 17098933 DOI: 10.1093/Nar/Gkl838 |
0.531 |
|
| 2006 |
Schaloske RH, Dennis EA. The phospholipase A2 superfamily and its group numbering system. Biochimica Et Biophysica Acta. 1761: 1246-59. PMID 16973413 DOI: 10.1016/J.Bbalip.2006.07.011 |
0.355 |
|
| 2006 |
Grkovich A, Johnson CA, Buczynski MW, Dennis EA. Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid phosphohydrolase-1-dependent. The Journal of Biological Chemistry. 281: 32978-87. PMID 16950767 DOI: 10.1074/Jbc.M605935200 |
0.802 |
|
| 2006 |
Stephens D, Barbayianni E, Constantinou-Kokotou V, Peristeraki A, Six DA, Cooper J, Harkewicz R, Deems RA, Dennis EA, Kokotos G. Differential inhibition of group IVA and group VIA phospholipases A2 by 2-oxoamides. Journal of Medicinal Chemistry. 49: 2821-8. PMID 16640343 DOI: 10.1021/Jm050993H |
0.71 |
|
| 2006 |
Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, ... ... Dennis EA, et al. Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. Journal of Lipid Research. 47: 1097-111. PMID 16479018 DOI: 10.1194/Jlr.M600027-Jlr200 |
0.595 |
|
| 2005 |
Winstead MV, Lucas KK, Dennis EA. Group IV cytosolic phospholipase A2 mediates arachidonic acid release in H9c2 rat cardiomyocyte cells in response to hydrogen peroxide. Prostaglandins & Other Lipid Mediators. 78: 55-66. PMID 16303605 DOI: 10.1016/J.Prostaglandins.2005.03.004 |
0.602 |
|
| 2005 |
Kessen UA, Schaloske RH, Stephens DL, Killermann Lucas K, Dennis EA. PGE2 release is independent of upregulation of Group V phospholipase A2 during long-term stimulation of P388D1 cells with LPS. Journal of Lipid Research. 46: 2488-96. PMID 16150819 DOI: 10.1194/Jlr.M500325-Jlr200 |
0.417 |
|
| 2005 |
Lucas KK, Dennis EA. Distinguishing phospholipase A2 types in biological samples by employing group-specific assays in the presence of inhibitors. Prostaglandins & Other Lipid Mediators. 77: 235-48. PMID 16099408 DOI: 10.1016/J.Prostaglandins.2005.02.004 |
0.595 |
|
| 2005 |
Shirai Y, Balsinde J, Dennis EA. Localization and functional interrelationships among cytosolic Group IV, secreted Group V, and Ca2+-independent Group VI phospholipase A2s in P388D1 macrophages using GFP/RFP constructs. Biochimica Et Biophysica Acta. 1735: 119-29. PMID 15967714 DOI: 10.1016/J.Bbalip.2005.05.005 |
0.654 |
|
| 2005 |
Svensson CI, Lucas KK, Hua XY, Powell HC, Dennis EA, Yaksh TL. Spinal phospholipase A2 in inflammatory hyperalgesia: role of the small, secretory phospholipase A2. Neuroscience. 133: 543-53. PMID 15885922 DOI: 10.1016/J.Neuroscience.2005.01.024 |
0.541 |
|
| 2005 |
Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, ... ... Dennis EA, et al. A comprehensive classification system for lipids. Journal of Lipid Research. 46: 839-61. PMID 15722563 DOI: 10.1194/Jlr.E400004-Jlr200 |
0.56 |
|
| 2005 |
Schaloske RH, Provins JW, Kessen UA, Dennis EA. Molecular characterization of the lipopolysaccharide/platelet activating factor- and zymosan-induced pathways leading to prostaglandin production in P388D1 macrophages. Biochimica Et Biophysica Acta. 1687: 64-75. PMID 15708354 DOI: 10.1016/J.Bbalip.2004.11.005 |
0.405 |
|
| 2005 |
Lucas KK, Svensson CI, Hua XY, Yaksh TL, Dennis EA. Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2. British Journal of Pharmacology. 144: 940-52. PMID 15685208 DOI: 10.1038/Sj.Bjp.0706116 |
0.556 |
|
| 2005 |
Constantinou-Kokotou V, Peristeraki A, Kokotos CG, Six DA, Dennis EA. Synthesis and activity of 2-oxoamides containing long chain beta-amino acids. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 431-5. PMID 15635664 DOI: 10.1002/Psc.628 |
0.686 |
|
| 2004 |
Kokotos G, Six DA, Loukas V, Smith T, Constantinou-Kokotou V, Hadjipavlou-Litina D, Kotsovolou S, Chiou A, Beltzner CC, Dennis EA. Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo. Journal of Medicinal Chemistry. 47: 3615-28. PMID 15214789 DOI: 10.1021/Jm030485C |
0.732 |
|
| 2004 |
Lucas KK, Dennis EA. The ABC's of Group IV cytosolic phospholipase A2. Biochimica Et Biophysica Acta. 1636: 213-8. PMID 15164769 DOI: 10.1016/J.Bbalip.2003.12.009 |
0.611 |
|
| 2003 |
Balboa MA, Shirai Y, Gaietta G, Ellisman MH, Balsinde J, Dennis EA. Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells. The Journal of Biological Chemistry. 278: 48059-65. PMID 12963740 DOI: 10.1074/Jbc.M305904200 |
0.756 |
|
| 2003 |
Phillips RM, Six DA, Dennis EA, Ghosh P. In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors. The Journal of Biological Chemistry. 278: 41326-32. PMID 12915403 DOI: 10.1074/Jbc.M302472200 |
0.738 |
|
| 2003 |
Six DA, Dennis EA. Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. The Journal of Biological Chemistry. 278: 23842-50. PMID 12672805 DOI: 10.1074/Jbc.M301386200 |
0.688 |
|
| 2003 |
Balsinde J, Dennis EA. Phospholipase A2 Signaling and Arachidonic Acid Release Handbook of Cell Signaling. 2: 261-263. DOI: 10.1016/B978-012124546-7/50527-1 |
0.577 |
|
| 2002 |
Whiles JA, Deems R, Vold RR, Dennis EA. Bicelles in structure-function studies of membrane-associated proteins. Bioorganic Chemistry. 30: 431-42. PMID 12642127 DOI: 10.1016/S0045-2068(02)00527-8 |
0.327 |
|
| 2002 |
Balboa MA, Varela-Nieto I, Killermann Lucas K, Dennis EA. Expression and function of phospholipase A(2) in brain. Febs Letters. 531: 12-7. PMID 12401195 DOI: 10.1016/S0014-5793(02)03481-6 |
0.625 |
|
| 2002 |
Balsinde J, Winstead MV, Dennis EA. Phospholipase A(2) regulation of arachidonic acid mobilization. Febs Letters. 531: 2-6. PMID 12401193 DOI: 10.1016/S0014-5793(02)03413-0 |
0.657 |
|
| 2002 |
Kokotos G, Kotsovolou S, Six DA, Constantinou-Kokotou V, Beltzner CC, Dennis EA. Novel 2-oxoamide inhibitors of human group IVA phospholipase A(2). Journal of Medicinal Chemistry. 45: 2891-3. PMID 12086476 DOI: 10.1021/Jm025538P |
0.695 |
|
| 2001 |
Bernatchez PN, Winstead MV, Dennis EA, Sirois MG. VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A 2 British Journal of Pharmacology. 134: 197-205. PMID 11522612 DOI: 10.1038/Sj.Bjp.0704215 |
0.346 |
|
| 2001 |
Balboa MA, Balsinde J, Dennis EA. Inflammatory activation of prostaglandin production by microglial cells antagonized by amyloid peptide Biochemical and Biophysical Research Communications. 280: 558-560. PMID 11162555 DOI: 10.1006/Bbrc.2000.4156 |
0.713 |
|
| 2000 |
Winstead MV, Balsinde J, Dennis EA. Calcium-independent phospholipase A2: Structure and function Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1488: 28-39. PMID 11080674 DOI: 10.1016/S1388-1981(00)00107-4 |
0.638 |
|
| 2000 |
Six DA, Dennis EA. The expanding superfamily of phospholipase A(2) enzymes: classification and characterization. Biochimica Et Biophysica Acta. 1488: 1-19. PMID 11080672 DOI: 10.1016/S1388-1981(00)00105-0 |
0.719 |
|
| 2000 |
Balsinde J, Balboa MA, Dennis EA. Group IV cytosolic phospholipase A2 activation by diacylglycerol pyrophosphate in murine P388D1 macrophages Annals of the New York Academy of Sciences. 905: 11-15. PMID 10818437 DOI: 10.1111/J.1749-6632.2000.Tb06533.X |
0.775 |
|
| 2000 |
Balsinde J, Balboa MA, Dennis EA. Identification of a third pathway for arachidonic acid mobilization and prostaglandin production in activated P388D macrophage-like cells Journal of Biological Chemistry. 275: 22544-22549. PMID 10811815 DOI: 10.1074/Jbc.M910163199 |
0.752 |
|
| 2000 |
Balsinde J, Balboa MA, Li WH, Llopis J, Dennis EA. Cellular regulation of cytosolic group IV phospholipase A2 by phosphatidylinositol bisphosphate levels Journal of Immunology. 164: 5398-5402. PMID 10799904 DOI: 10.4049/Jimmunol.164.10.5398 |
0.77 |
|
| 2000 |
Wang A, Johnson CA, Jones Y, Ellisman MH, Dennis EA. Subcellular localization and PKC-dependent regulation of the human lysophospholipase A/acyl-protein thioesterase in WISH cells. Biochimica Et Biophysica Acta. 1484: 207-14. PMID 10760470 DOI: 10.1016/S1388-1981(00)00020-2 |
0.591 |
|
| 2000 |
Johansen B, Rakkestad K, Balboa MA, Dennis EA. Expression of cytosolic and secreted forms of phospholipase A2 and cyclooxygenases in human placenta, fetal membranes, and chorionic cell lines Prostaglandins and Other Lipid Mediators. 60: 119-125. PMID 10751642 DOI: 10.1016/S0090-6980(99)00057-X |
0.656 |
|
| 2000 |
Bianco ID, Balsinde J, Beltramo DM, Castagna LF, Landa CA, Dennis EA. Chitosan-induced phospholipase A2 activation and arachidonic acid mobilization in P388D1 macrophages. Febs Letters. 466: 292-4. PMID 10682846 DOI: 10.1016/S0014-5793(00)01089-9 |
0.677 |
|
| 2000 |
Dennis EA. Phospholipase A2 in eicosanoid generation American Journal of Respiratory and Critical Care Medicine. 161: S32-S35. PMID 10673223 DOI: 10.1164/Ajrccm.161.Supplement_1.Ltta-7 |
0.405 |
|
| 2000 |
Balsinde J, Balboa MA, Yedgar S, Dennis EA. Group V phospholipase A2-mediated oleic acid mobilization in lipopolysaccharide-stimulated P388D1 macrophages Journal of Biological Chemistry. 275: 4783-4786. PMID 10671511 DOI: 10.1074/Jbc.275.7.4783 |
0.751 |
|
| 2000 |
Balboa MA, Balsinde J, Dennis EA. Phosphorylation of cytosolic group IV phospholipase A2 is necessary but not sufficient for arachidonic acid release in P388D1 macrophages Biochemical and Biophysical Research Communications. 267: 145-148. PMID 10623589 DOI: 10.1006/Bbrc.1999.1964 |
0.753 |
|
| 1999 |
Balboa MA, Balsinde J, Johnson CA, Dennis EA. Regulation of arachidonic acid mobilization in lipopolysaccharide-activated P388D(1) macrophages by adenosine triphosphate. The Journal of Biological Chemistry. 274: 36764-8. PMID 10593984 DOI: 10.1074/Jbc.274.51.36764 |
0.794 |
|
| 1999 |
Lefkowitz LJ, Deems RA, Dennis EA. Expression of group IA phospholipase A2 in Pichia pastoris: Identification of a phosphatidylcholine activator site using site-directed mutagenesis Biochemistry. 38: 14174-14184. PMID 10571991 DOI: 10.1021/Bi991432T |
0.315 |
|
| 1999 |
Johnson CA, Balboa MA, Balsinde J, Dennis EA. Regulation of cyclooxygenase-2 expression by phosphatidate phosphohydrolase in human amnionic WISH cells. The Journal of Biological Chemistry. 274: 27689-93. PMID 10488110 DOI: 10.1074/Jbc.274.39.27689 |
0.789 |
|
| 1999 |
Balsinde J, Shinohara H, Lefkowitz LJ, Johnson CA, Balboa MA, Dennis EA. Group V phospholipase A(2)-dependent induction of cyclooxygenase-2 in macrophages. The Journal of Biological Chemistry. 274: 25967-70. PMID 10473537 DOI: 10.1074/Jbc.274.37.25967 |
0.782 |
|
| 1999 |
Yang HC, Mosior M, Ni B, Dennis EA. Regional distribution, ontogeny, purification, and characterization of the Ca2+-independent phospholipase A2 from rat brain Journal of Neurochemistry. 73: 1278-1287. PMID 10461922 DOI: 10.1046/J.1471-4159.1999.0731278.X |
0.368 |
|
| 1999 |
Ghomashchi F, Loo R, Balsinde J, Bartoli F, Apitz-Castro R, Clark JD, Dennis EA, Gelb MH. Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A2: Structure-function studies with vesicle, micelle, and membrane assays Biochimica Et Biophysica Acta - Biomembranes. 1420: 45-56. PMID 10446289 DOI: 10.1016/S0005-2736(99)00056-5 |
0.626 |
|
| 1999 |
Bird DA, Gillotte KL, Horkko S, Friedman P, Dennis EA, Witztum JL, Steinberg D. Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: Implications with respect to macrophage recognition of apoptotic cells Proceedings of the National Academy of Sciences of the United States of America. 96: 6347-6352. PMID 10339590 DOI: 10.1073/Pnas.96.11.6347 |
0.35 |
|
| 1999 |
Balsinde J, Balboa MA, Insel PA, Dennis EA. Regulation and inhibition of phospholipase A2. Annual Review of Pharmacology and Toxicology. 39: 175-89. PMID 10331081 DOI: 10.1146/Annurev.Pharmtox.39.1.175 |
0.795 |
|
| 1999 |
Yang HC, Mosior M, Johnson CA, Chen Y, Dennis EA. Group-specific assays that distinguish between the four major types of mammalian phospholipase A2. Analytical Biochemistry. 269: 278-88. PMID 10221999 DOI: 10.1006/Abio.1999.4053 |
0.621 |
|
| 1999 |
Shinohara H, Balboa MA, Johnson CA, Balsinde J, Dennis EA. Regulation of delayed prostaglandin production in activated P388D1 macrophages by group IV cytosolic and group V secretory phospholipase A2s. The Journal of Biological Chemistry. 274: 12263-8. PMID 10212194 DOI: 10.1074/Jbc.274.18.12263 |
0.803 |
|
| 1999 |
Wang A, Yang HC, Friedman P, Johnson CA, Dennis EA. A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization. Biochimica Et Biophysica Acta. 1437: 157-69. PMID 10064899 DOI: 10.1016/S1388-1981(99)00012-8 |
0.57 |
|
| 1999 |
Hörkkö S, Bird DA, Miller E, Itabe H, Leitinger N, Subbanagounder G, Berliner JA, Friedman P, Dennis EA, Curtiss LK, Palinski W, Witztum JL. Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. The Journal of Clinical Investigation. 103: 117-28. PMID 9884341 DOI: 10.1172/Jci4533 |
0.306 |
|
| 1999 |
Balboa MA, Balsinde J, Dillon DA, Carman GM, Dennis EA. Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate. The Journal of Biological Chemistry. 274: 522-6. PMID 9867874 DOI: 10.1074/Jbc.274.1.522 |
0.765 |
|
| 1999 |
Dennis EA, Balsinde J, Balboa M. Distinct function of each type of phospholipase A2 and cyclooxygenase in eicosanoid production Prostaglandins & Other Lipid Mediators. 59: 35. DOI: 10.1016/S0090-6980(99)90270-8 |
0.716 |
|
| 1998 |
Chen Y, Dennis EA. Expression and characterization of human group V phospholipase A2. Biochimica Et Biophysica Acta. 1394: 57-64. PMID 9767110 DOI: 10.1016/S0005-2760(98)00098-8 |
0.445 |
|
| 1998 |
Balsinde J, Balboa MA, Dennis EA. Functional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2. Proceedings of the National Academy of Sciences of the United States of America. 95: 7951-6. PMID 9653121 DOI: 10.1073/Pnas.95.14.7951 |
0.772 |
|
| 1998 |
Lio YC, Dennis EA. Interfacial activation, lysophospholipase and transacylase activity of group VI Ca2+-independent phospholipase A2. Biochimica Et Biophysica Acta. 1392: 320-32. PMID 9630702 DOI: 10.1016/S0005-2760(98)00049-6 |
0.441 |
|
| 1998 |
Balboa MA, Balsinde J, Dennis EA. Involvement of phosphatidate phosphohydrolase in arachidonic acid mobilization in human amnionic WISH cells. The Journal of Biological Chemistry. 273: 7684-90. PMID 9516474 DOI: 10.1074/Jbc.273.13.7684 |
0.766 |
|
| 1998 |
Mosior M, Six DA, Dennis EA. Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity. The Journal of Biological Chemistry. 273: 2184-91. PMID 9442060 DOI: 10.1074/Jbc.273.4.2184 |
0.7 |
|
| 1997 |
Balsinde J, Balboa MA, Dennis EA. Antisense inhibition of group VI Ca2+-independent phospholipase A2 blocks phospholipid fatty acid remodeling in murine P388D1 macrophages. The Journal of Biological Chemistry. 272: 29317-21. PMID 9361012 DOI: 10.1074/Jbc.272.46.29317 |
0.786 |
|
| 1997 |
Balsinde J, Dennis EA. Function of calcium-independent phospholipase A2 in arachidonic acid metabolism in P388D1 macrophages. Advances in Experimental Medicine and Biology. 407: 99-103. PMID 9321938 DOI: 10.1007/978-1-4899-1813-0_15 |
0.653 |
|
| 1997 |
Wang A, Loo R, Chen Z, Dennis EA. Regiospecificity and catalytic triad of lysophospholipase I. The Journal of Biological Chemistry. 272: 22030-6. PMID 9268342 DOI: 10.1074/Jbc.272.35.22030 |
0.33 |
|
| 1997 |
Balsinde J, Balboa MA, Dennis EA. Inflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesis. The Journal of Biological Chemistry. 272: 20373-7. PMID 9252342 DOI: 10.1074/Jbc.272.33.20373 |
0.771 |
|
| 1997 |
Loo RW, Conde-Frieboes K, Reynolds LJ, Dennis EA. Activation, inhibition, and regiospecificity of the lysophospholipase activity of the 85-kDa group IV cytosolic phospholipase A2 Journal of Biological Chemistry. 272: 19214-19219. PMID 9235913 DOI: 10.1074/Jbc.272.31.19214 |
0.445 |
|
| 1997 |
Balsinde J, Dennis EA. Function and inhibition of intracellular calcium-independent phospholipase A2. The Journal of Biological Chemistry. 272: 16069-72. PMID 9195897 DOI: 10.1074/Jbc.272.26.16069 |
0.591 |
|
| 1997 |
Wang A, Deems RA, Dennis EA. Cloning, expression, and catalytic mechanism of murine lysophospholipase I. The Journal of Biological Chemistry. 272: 12723-9. PMID 9139730 DOI: 10.1074/Jbc.272.19.12723 |
0.364 |
|
| 1997 |
Balboa MA, Balsinde J, Jones SS, Dennis EA. Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells. The Journal of Biological Chemistry. 272: 8576-80. PMID 9079688 DOI: 10.1074/Jbc.272.13.8576 |
0.743 |
|
| 1997 |
Balsinde J, Balboa MA, Insel PA, Dennis EA. Differential regulation of phospholipase D and phospholipase A2 by protein kinase C in P388D1 macrophages. The Biochemical Journal. 321: 805-9. PMID 9032469 DOI: 10.1042/Bj3210805 |
0.798 |
|
| 1997 |
Dennis EA. The growing phospholipase A2 superfamily of signal transduction enzymes. Trends in Biochemical Sciences. 22: 1-2. PMID 9020581 DOI: 10.1016/S0968-0004(96)20031-3 |
0.343 |
|
| 1997 |
Balboa MA, Balsinde J, Winstead MV, Tischfield JA, Dennis EA. Novel group V phospholipase A2 involved in arachidonic acid mobilization in murine P388D1 macrophages. The Journal of Biological Chemistry. 271: 32381-4. PMID 8943302 DOI: 10.1074/Jbc.271.50.32381 |
0.765 |
|
| 1997 |
Balsinde J, Dennis EA. Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages. The Journal of Biological Chemistry. 271: 31937-41. PMID 8943239 DOI: 10.1074/Jbc.271.50.31937 |
0.648 |
|
| 1996 |
Pickard RT, Grace Chiou X, Strifler BA, DeFelippis MR, Hyslop PA, Tebbe AL, Yee YK, Reynolds LJ, Dennis EA, Kramer RM, Sharp JD. Identification of essential residues for the catalytic function of 85- kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine Journal of Biological Chemistry. 271: 19225-19231. PMID 8702602 DOI: 10.1074/Jbc.271.32.19225 |
0.372 |
|
| 1996 |
Lio YC, Reynolds LJ, Balsinde J, Dennis EA. Irreversible inhibition of Ca2+-independent phospholipase A2 by methyl arachidonyl fluorophosphonate Biochimica Et Biophysica Acta - Lipids and Lipid Metabolism. 1302: 55-60. PMID 8695655 DOI: 10.1016/0005-2760(96)00002-1 |
0.649 |
|
| 1996 |
Balsinde J, Dennis EA. The incorporation of arachidonic acid into triacylglycerol in P388D1 macrophage-like cells. European Journal of Biochemistry. 235: 480-5. PMID 8654391 DOI: 10.1111/J.1432-1033.1996.00480.X |
0.618 |
|
| 1996 |
Balsinde J, Dennis EA. Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages. The Journal of Biological Chemistry. 271: 6758-65. PMID 8636097 DOI: 10.1074/Jbc.271.12.6758 |
0.666 |
|
| 1996 |
Conde-Frieboes K, Reynolds LJ, Lio YC, Hale MR, Wasserman HH, Dennis EA. Activated ketones as inhibitors of intracellular Ca2+-dependent and Ca2+-independent phospholipase A2 Journal of the American Chemical Society. 118: 5519-5525. DOI: 10.1021/Ja953553W |
0.379 |
|
| 1995 |
Ackermann EJ, Conde-Frieboes K, Dennis EA. Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones. The Journal of Biological Chemistry. 270: 445-50. PMID 7814408 DOI: 10.1074/Jbc.270.1.445 |
0.386 |
|
| 1995 |
Plesniak LA, Yu L, Dennis EA. Conformation of micellar phospholipid bound to the active site of phospholipase A2. Biochemistry. 34: 4943-51. PMID 7711016 DOI: 10.1021/Bi00015A005 |
0.371 |
|
| 1995 |
Balsinde J, Bianco ID, Ackermann EJ, Conde-Frieboes K, Dennis EA. Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages. Proceedings of the National Academy of Sciences of the United States of America. 92: 8527-31. PMID 7667324 DOI: 10.1073/Pnas.92.18.8527 |
0.662 |
|
| 1995 |
Carman GM, Deems RA, Dennis EA. Lipid signaling enzymes and surface dilution kinetics. The Journal of Biological Chemistry. 270: 18711-4. PMID 7642515 DOI: 10.1074/Jbc.270.32.18711 |
0.309 |
|
| 1995 |
Bianco ID, Kelley MJ, Crowl RM, Dennis EA. Identification of two specific lysines responsible for the inhibition of phospholipase A2 by manoalide. Biochimica Et Biophysica Acta. 1250: 197-203. PMID 7632725 DOI: 10.1016/0167-4838(95)00051-U |
0.366 |
|
| 1995 |
Balboa MA, Balsinde J, Dennis EA, Insel PA. A phospholipase D-mediated pathway for generating diacylglycerol in nuclei from Madin-Darby canine kidney cells. The Journal of Biological Chemistry. 270: 11738-40. PMID 7538121 DOI: 10.1074/Jbc.270.20.11738 |
0.768 |
|
| 1994 |
Reynolds LJ, Hughes LL, Yu L, Dennis EA. 1-Hexadecyl-2-arachidonoylthio-2-deoxy-sn-glycero-3-phosphorylcholine as a substrate for the microtiterplate assay of human cytosolic phospholipase A2 Analytical Biochemistry. 217: 25-32. PMID 8203736 DOI: 10.1006/Abio.1994.1079 |
0.369 |
|
| 1994 |
Asmis R, Randriamampita C, Tsien RY, Dennis EA. Intracellular Ca2+, inositol 1,4,5-trisphosphate and additional signalling in the stimulation by platelet-activating factor of prostaglandin E2 formation in P388D1 macrophage-like cells Biochemical Journal. 298: 543-551. PMID 8141766 DOI: 10.1042/Bj2980543 |
0.63 |
|
| 1994 |
Asmis R, Dennis EA. PAF stimulates cAMP formation in P388D1 macrophage-like cells via the formation and secretion of prostaglandin E2 in an autocrine fashion Bba - Molecular Cell Research. 1224: 295-301. PMID 7981245 DOI: 10.1016/0167-4889(94)90203-8 |
0.64 |
|
| 1994 |
Balsinde J, Barbour SE, Bianco ID, Dennis EA. Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes. Proceedings of the National Academy of Sciences of the United States of America. 91: 11060-4. PMID 7972009 DOI: 10.1073/Pnas.91.23.11060 |
0.795 |
|
| 1994 |
Asmis R, Dennis EA. Regulation of prostaglandin E2 production in P388D1 macrophage-like cells Annals of the New York Academy of Sciences. 744: 1-10. PMID 7825831 DOI: 10.1111/J.1749-6632.1994.Tb52718.X |
0.61 |
|
| 1993 |
Plesniak LA, Boegeman SC, Segelke BW, Dennis EA. Interaction of phospholipase A2 with thioether amide containing phospholipid analogues. Biochemistry. 32: 5009-16. PMID 8494876 DOI: 10.1021/Bi00070A006 |
0.35 |
|
| 1993 |
Reynolds LJ, Hughes LL, Louis AI, Kramer RM, Dennis EA. Metal ion and salt effects on the phospholipase A2, lysophospholipase, and transacylase activities of human cytosolic phospholipase A2. Biochimica Et Biophysica Acta. 1167: 272-80. PMID 8481388 DOI: 10.1016/0005-2760(93)90229-3 |
0.401 |
|
| 1993 |
Stafford RE, Zhang YY, Deems RA, Dennis EA. Kinetic analysis and substrate specificity of a lysophospholipase from the macrophage-like cell line P388D1. Biochimica Et Biophysica Acta. 1167: 43-8. PMID 8461331 DOI: 10.1016/0005-2760(93)90215-U |
0.374 |
|
| 1993 |
Yu L, Dennis EA. Effect of polar head groups on the interactions of phospholipase A2 with phosphonate transition-state analogues. Biochemistry. 32: 10185-92. PMID 8399145 DOI: 10.1021/Bi00089A039 |
0.386 |
|
| 1992 |
Kelley MJ, Crowl RM, Dennis EA. Renaturation of cobra venom phospholipase A2 expressed from a synthetic gene in Escherichia coli. Biochimica Et Biophysica Acta. 1118: 107-15. PMID 1730025 DOI: 10.1016/0167-4838(92)90136-2 |
0.352 |
|
| 1992 |
Dennis EA, Deems RA, Yu L. Extracellular phospholipase A2. Advances in Experimental Medicine and Biology. 318: 35-9. PMID 1636503 DOI: 10.1007/978-1-4615-3426-6_4 |
0.429 |
|
| 1992 |
Reynolds LJ, Hughes LL, Dennis EA. Analysis of human synovial fluid phospholipase A2 on short chain phosphatidylcholine-mixed micelles: Development of a spectrophotometric assay suitable for a microtiterplate reader Analytical Biochemistry. 204: 190-197. PMID 1514686 DOI: 10.1016/0003-2697(92)90160-9 |
0.36 |
|
| 1992 |
Dennis EA. The biosynthesis of phospholipids. Methods in Enzymology. 209: 1-4. PMID 1495408 DOI: 10.1016/0076-6879(92)09003-L |
0.321 |
|
| 1992 |
Davidson FF, Dennis EA. Limitations of phosphatidylcholine/deoxycholate mixtures for the analysis of phospholipase A2 inhibition and activation: illustration with annexins. Biochimica Et Biophysica Acta. 1127: 270-6. PMID 1387325 DOI: 10.1016/0005-2760(92)90231-J |
0.381 |
|
| 1992 |
Yu L, Dennis EA. Defining the dimensions of the catalytic site of phospholipase A2 using amide substrate analogs Journal of the American Chemical Society. 114: 8757-8763. DOI: 10.1021/Ja00049A001 |
0.317 |
|
| 1992 |
Lin Y, Dennis EA. Kinetic analysis of the competitive inhibition of phospholipase A2 in triton X-100 mixed micelles Bioorganic & Medicinal Chemistry Letters. 2: 1343-1348. DOI: 10.1016/S0960-894X(00)80509-0 |
0.344 |
|
| 1991 |
Hazlett TL, Deems RA, Dennis EA. Activation, aggregation, inhibition and the mechanism of phospholipase A2. Advances in Experimental Medicine and Biology. 279: 49-64. PMID 2096700 DOI: 10.1007/978-1-4613-0651-1_4 |
0.427 |
|
| 1991 |
Zhang YY, Deems RA, Dennis EA. Lysophospholipases I and II from P388D1 macrophage-like cell line. Methods in Enzymology. 197: 456-68. PMID 2051937 DOI: 10.1016/0076-6879(91)97171-T |
0.376 |
|
| 1991 |
Reynolds LJ, Dennis EA. Cobra venom phospholipase A2: Naja naja naja Methods in Enzymology. 197: 359-365. PMID 2051932 DOI: 10.1016/0076-6879(91)97161-Q |
0.336 |
|
| 1991 |
Reynolds LJ, Washburn WN, Deems RA, Dennis EA. Assay strategies and methods for phospholipases Methods in Enzymology. 197: 3-23. PMID 2051923 DOI: 10.1016/0076-6879(91)97129-M |
0.305 |
|
| 1991 |
Yu L, Dennis EA. Critical role of a hydrogen bond in the interaction of phospholipase A2 with transition-state and substrate analogues. Proceedings of the National Academy of Sciences of the United States of America. 88: 9325-9. PMID 1924395 DOI: 10.1073/Pnas.88.20.9325 |
0.336 |
|
| 1991 |
Dennis EA, Rhee SG, Billah MM, Hannun YA. Role of phospholipase in generating lipid second messengers in signal transduction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2068-77. PMID 1901288 DOI: 10.1096/Fasebj.5.7.1901288 |
0.405 |
|
| 1990 |
Davidson FF, Dennis EA. Biological relevance of lipocortins and related proteins as inhibitors of phospholipase A2. Biochemical Pharmacology. 38: 3645-51. PMID 2532012 DOI: 10.1016/0006-2952(89)90567-4 |
0.36 |
|
| 1990 |
Davidson FF, Dennis EA. Amino acid sequence and circular dichroism of Indian cobra (Naja naja naja) venom acidic phospholipase A2. Biochimica Et Biophysica Acta. 1037: 7-15. PMID 2294972 DOI: 10.1016/0167-4838(90)90095-W |
0.331 |
|
| 1990 |
Glaser KB, Lister MD, Ulevitch RJ, Dennis EA. Macrophage phospholipase A2 activity and eicosanoid production: studies with phospholipase A2 inhibitors in P388D1 cells. Advances in Experimental Medicine and Biology. 275: 1-16. PMID 2239440 DOI: 10.1007/978-1-4684-5805-3_1 |
0.455 |
|
| 1990 |
Davidson FF, Dennis EA. Evolutionary relationships and implications for the regulation of phospholipase A2 from snake venom to human secreted forms. Journal of Molecular Evolution. 31: 228-38. PMID 2120459 DOI: 10.1007/Bf02109500 |
0.383 |
|
| 1990 |
Washburn WN, Dennis EA. Suicide-inhibitory bifunctionally linked substrates (SIBLINKS) as phospholipase A2 inhibitors Journal of the American Chemical Society. 112: 2042-2043. DOI: 10.1021/Ja00161A083 |
0.332 |
|
| 1990 |
Washburn WN, Dennis EA. Novel general approach for the assay and inhibition of hydrolytic enzymes utilizing suicide-inhibitory bifunctionally linked substrates (SIBLINKS): exemplified by a phospholipase A2 assay Journal of the American Chemical Society. 112: 2040-2041. DOI: 10.1021/Ja00161A082 |
0.344 |
|
| 1989 |
Fanni T, Deems RA, Dennis EA. 18O isotope exchange experiments on phospholipase A2 determined by 13C-NMR: monomeric phosphatidylcholine and micellar phosphatidylethanolamine substrates. Biochimica Et Biophysica Acta. 1004: 134-8. PMID 2742867 DOI: 10.1016/0005-2760(89)90223-3 |
0.343 |
|
| 1988 |
Hazlett TL, Dennis EA. Lipid-induced aggregation of phospholipase A2: sucrose density gradient ultracentrifugation and crosslinking studies. Biochimica Et Biophysica Acta. 961: 22-9. PMID 3382690 DOI: 10.1016/0005-2760(88)90126-9 |
0.373 |
|
| 1988 |
Hazlett TL, Dennis EA. Effect of phospholipids on fluorescence polarization and lifetimes of fluorescein-labeled phospholipase A2. Biochimica Et Biophysica Acta. 958: 172-8. PMID 3337833 DOI: 10.1016/0005-2760(88)90174-9 |
0.372 |
|
| 1988 |
Reynolds LJ, Morgan BP, Hite GA, Mihelich ED, Dennis EA. Phospholipase A2 inhibition and modification by manoalogue Journal of the American Chemical Society. 110: 5172-5177. DOI: 10.1021/Ja00223A044 |
0.338 |
|
| 1987 |
Deems RA, Lombardo D, Morgan BP, Mihelich ED, Dennis EA. The inhibition of phospholipase A2 by manoalide and manoalide analogues. Biochimica Et Biophysica Acta. 917: 258-68. PMID 3801502 DOI: 10.1016/0005-2760(87)90130-5 |
0.322 |
|
| 1987 |
Dennis EA. Regulation of Eicosanoid Production: Role of Phospholipases and Inhibitors Nature Biotechnology. 5: 1294-1300. DOI: 10.1038/Nbt1287-1294 |
0.458 |
|
| 1987 |
Dennis EA. Phospholipase A2 mechanism: Inhibition and role in arachidonic acid release Drug Development Research. 10: 205-220. DOI: 10.1002/Ddr.430100404 |
0.42 |
|
| 1986 |
Plückthun A, DeBony J, Fanni T, Dennis EA. Conformation of fatty acyl chains in alpha- and beta-phosphatidylcholine and phosphatidylethanolamine derivatives in sonicated vesicles. Biochimica Et Biophysica Acta. 856: 144-54. PMID 3955032 DOI: 10.1016/0005-2736(86)90021-0 |
0.473 |
|
| 1986 |
Hazlett TL, Dennis EA. Aggregation studies on fluorescein-coupled cobra venom phospholipase A2. Biochemistry. 24: 6152-8. PMID 3936540 DOI: 10.1021/Bi00343A018 |
0.329 |
|
| 1986 |
Davidson FF, Hajdu J, Dennis EA. 1-Stearyl,2-stearoylaminodeoxy phosphatidylcholine, a potent reversible inhibitor of phospholipase A2. Biochemical and Biophysical Research Communications. 137: 587-92. PMID 3755338 DOI: 10.1016/0006-291X(86)91118-6 |
0.386 |
|
| 1986 |
Lombardo D, Fanni T, Plückthun A, Dennis EA. Rate-determining step in phospholipase A2 mechanism. 18O isotope exchange determined by 13C NMR. The Journal of Biological Chemistry. 261: 11663-6. PMID 3745162 |
0.402 |
|
| 1985 |
Plückthun A, Rohlfs R, Davidson FF, Dennis EA. Short-chain phosphatidylethanolamines: physical properties and susceptibility of the monomers to phospholipase A2 action. Biochemistry. 24: 4201-8. PMID 4052390 DOI: 10.1021/Bi00336A058 |
0.489 |
|
| 1985 |
Plückthun A, Dennis EA. Activation, aggregation, and product inhibition of cobra venom phospholipase A2 and comparison with other phospholipases. The Journal of Biological Chemistry. 260: 11099-106. PMID 4030786 |
0.498 |
|
| 1985 |
Ross MI, Deems RA, Jesaitis AJ, Dennis EA, Ulevitch RJ. Phospholipase activities of the P388D1 macrophage-like cell line Archives of Biochemistry and Biophysics. 238: 247-258. PMID 3985620 DOI: 10.1016/0003-9861(85)90162-6 |
0.403 |
|
| 1985 |
Hazlett TL, Dennis EA. Affinity chromatography of phospholipase A2 from Naja naja naja (Indian cobra) venom. Toxicon : Official Journal of the International Society On Toxinology. 23: 457-66. PMID 3927524 DOI: 10.1016/0041-0101(85)90029-7 |
0.326 |
|
| 1983 |
Vogel CW, Plückthun A, Podack ER, Dennis EA, Müller-Eberhard HJ. The membrane attack complex of complement and its precursor proteins lack phospholipase activity. Molecular Immunology. 20: 377-82. PMID 6865955 DOI: 10.1016/0161-5890(83)90019-6 |
0.513 |
|
| 1982 |
Plückthun A, Dennis EA. Role of monomeric activators in cobra venom phospholipase A2 action. Biochemistry. 21: 1750-6. PMID 7082644 DOI: 10.1021/Bi00537A008 |
0.555 |
|
| 1982 |
Plückthun A, Dennis EA. Acyl and phosphoryl migration in lysophospholipids: importance in phospholipid synthesis and phospholipase specificity. Biochemistry. 21: 1743-50. PMID 7082643 DOI: 10.1021/Bi00537A007 |
0.492 |
|
| 1981 |
Darke PL, Jarvis AA, Deems RA, Dennis EA. Further characterization and N-terminal sequence of cobra venom phospholipase A2. Biochimica Et Biophysica Acta. 626: 154-61. PMID 7459378 DOI: 10.1016/0005-2795(80)90206-8 |
0.385 |
|
| 1981 |
Vogel CW, Plückthun A, Müller-Eberhard HJ, Dennis EA. Hemolytic assay for venom phospholipase A2. Analytical Biochemistry. 118: 262-8. PMID 7337224 DOI: 10.1016/0003-2697(81)90189-5 |
0.52 |
|
| 1981 |
Deems RA, Dennis EA. Phospholipase A2 from cobra venom (Naja naja naja). Methods in Enzymology. 703-10. PMID 7278679 DOI: 10.1016/0076-6879(81)71083-8 |
0.309 |
|
| 1981 |
Dennis EA, Darke PL, Deems RA, Kensil CR, Plückthun A. Cobra venom phospholipase A2: a review of its action toward lipid/water interfaces. Molecular and Cellular Biochemistry. 36: 37-45. PMID 7242529 DOI: 10.1007/Bf02354830 |
0.54 |
|
| 1979 |
Adamich M, Roberts MF, Dennis EA. Phospholipid activation of cobra venom phospholipase A2. 2. Characterization of the phospholipid--enzyme interaction. Biochemistry. 18: 3308-14. PMID 465469 DOI: 10.1021/Bi00582A017 |
0.558 |
|
| 1979 |
Roberts MF, Adamich M, Robson RJ, Dennis EA. Phospholipid activation of cobra venom phospholipase A2. 1. Lipid--lipid or lipid--enzyme interaction. Biochemistry. 18: 3301-8. PMID 465468 DOI: 10.1021/Bi00582A016 |
0.552 |
|
| 1978 |
Dennis EA. Mechanism of phospholipase A2 action toward mixed micelles of detergent and phospholipids. Advances in Experimental Medicine and Biology. 101: 165-75. PMID 665362 DOI: 10.1007/978-1-4615-9071-2_15 |
0.383 |
|
| 1978 |
Shaw JO, Roberts MF, Ulevitch RJ, Henson P, Dennis EA. Phospholipase A2 contamination of cobra venom factor preparations. Biologic role in complement-dependent in vivo reactions and inactivation with p-bromophenacyl bromide. The American Journal of Pathology. 91: 517-30. PMID 655262 |
0.484 |
|
| 1978 |
Roberts MF, Otnaess AB, Kensil CA, Dennis EA. The specificity of phospholipase A2 and phospholipase C in a mixed micellar system. The Journal of Biological Chemistry. 253: 1252-7. PMID 624729 |
0.445 |
|
| 1978 |
Adamich M, Dennis EA. Specificity reversal in phospholipase A2 hydrolysis of lipid mixtures. Biochemical and Biophysical Research Communications. 80: 424-8. PMID 623670 DOI: 10.1016/0006-291X(78)90694-0 |
0.369 |
|
| 1978 |
Roberts MF, Bothner-By AA, Dennis EA. Magnetic nonequivalence within fatty acyl chains of phospholipids in membrane models: 1H nuclear magnetic resonance studies of the alpha-methylene groups. Biochemistry. 17: 935-42. PMID 580222 DOI: 10.1021/Bi00598A030 |
0.468 |
|
| 1978 |
Adamich M, Voss HF, Dennis EA. Cobra venom phospholipase A2 immobilized to porocus glass beads. Archives of Biochemistry and Biophysics. 189: 417-23. PMID 30410 DOI: 10.1016/0003-9861(78)90229-1 |
0.343 |
|
| 1977 |
Lewis RV, Roberts MF, Dennis EA, Allison WS. Photoactivated heterobifunctional cross-linking reagents which demonstrate the aggregation state of phospholipase A2. Biochemistry. 16: 5650-4. PMID 921957 DOI: 10.1021/Bi00644A041 |
0.536 |
|
| 1977 |
Roberts MF, Dennis EA. Proton nuclear magnetic resonance demonstration of conformationally nonequivalent phospholipid fatty acid chains in mixed micelles. Journal of the American Chemical Society. 99: 6142-3. PMID 893884 DOI: 10.1002/Chin.197749062 |
0.482 |
|
| 1977 |
Roberts MF, Deems RA, Dennis EA. Dual role of interfacial phospholipid in phospholipase A2 catalysis. Proceedings of the National Academy of Sciences of the United States of America. 74: 1950-4. PMID 266715 DOI: 10.1073/Pnas.74.5.1950 |
0.557 |
|
| 1977 |
Roberts MF, Deems RA, Dennis EA. Spectral perturbations of the histidine and tryptophan in cobra venom phospholipase A2 upon metal ion and mixed micelle binding. The Journal of Biological Chemistry. 252: 6011-7. PMID 19461 |
0.409 |
|
| 1977 |
Roberts MF, Deems RA, Mincey TC, Dennis EA. Chemical modification of the histidine residue in phospholipase A2 (Naja naja naja). A case of half-site reactivity. The Journal of Biological Chemistry. 252: 2405-11. PMID 14964 |
0.503 |
|
| 1975 |
Dennis EA. Interaction of enzymes with mixed micelles of phospholipid and detergent: analysis of the phospholipase A2--dipalmitoyl phosphadidycholine--Triton X 100 system. Journal of Supramolecular Structure. 2: 682-94. PMID 4461851 DOI: 10.1002/Jss.400020513 |
0.344 |
|
| 1975 |
Warner TG, Dennis EA. Phosphatidylserine decarboxylase: analysis of its action towards unsaturated and saturated phosphatidylserine and the effect of Triton X-100 on activity. Archives of Biochemistry and Biophysics. 167: 761-8. PMID 235903 DOI: 10.1016/0003-9861(75)90522-6 |
0.374 |
|
| 1974 |
Dennis EA. Phospholipase A2 activity towards phosphatidylcholine in mixed micelles: surface dilution kinetics and the effect of thermotropic phase transitions. Archives of Biochemistry and Biophysics. 158: 485-93. PMID 4798723 DOI: 10.1016/0003-9861(73)90540-7 |
0.349 |
|
| 1972 |
Dennis EA, Kennedy EP. Intracellular sites of lipid synthesis and the biogenesis of mitochondria. Journal of Lipid Research. 13: 263-7. PMID 5016308 |
0.521 |
|
| 1970 |
Dennis EA, Kennedy EP. Enzymatic synthesis and decarboxylation of phosphatidylserine in Tetrahymena pyriformis. Journal of Lipid Research. 11: 394-403. PMID 5501474 |
0.486 |
|
| 1970 |
KLUGER R, COVITZ F, DENNIS E, WILLIAMS LD, WESTHEIMER FH. ChemInform Abstract: PH-ABHAENGIGE PRODUKT- UND GESCHWINDIGKEITSPROFILE BEI HYDROLYSE VON METHYLAETHYLENPHOSPHAT(I), GESCHWINDIGKEITSBESTIMMENDE PSEUDOROTATION Chemischer Informationsdienst. Organische Chemie. 1. DOI: 10.1002/Chin.197002122 |
0.606 |
|
| 1969 |
Kluger R, Covitz F, Dennis E, Williams LD, Westheimer FH. pH-product and pH-rate profiles for the hydrolysis of methyl ethylene phosphate. Rate-limiting pseudorotation Journal of the American Chemical Society. 91: 6066-6072. DOI: 10.1021/Ja01050A023 |
0.624 |
|
| 1967 |
Kluger R, Kerst F, Lee DG, Dennis EA, Westheimer FH. Hydrolysis of Esters of Bicycloheptyl- and -heptenylphsophinic Acids Journal of the American Chemical Society. 89: 3718-3719. DOI: 10.1021/Ja00991A601 |
0.728 |
|
| 1967 |
Kluger R, Kerst F, Lee DG, Dennis EA, Westheimer FH. Hydrolysis of esters of bicycloheptyl- and -heptenylphosphinic acids [17] Journal of the American Chemical Society. 89: 3918-3919. |
0.514 |
|
| 1966 |
Dennis EA, Westheimer FH. The geometry of the transition state in the hydrolysis of phosphate esters. Journal of the American Chemical Society. 88: 3432-3. PMID 5946603 DOI: 10.1021/Ja00966A046 |
0.506 |
|
| 1966 |
Dennis EA, Westheimer FH. The rates of hydrolysis of esters of cyclic phosphinic acids. Journal of the American Chemical Society. 88: 3431. PMID 5946602 DOI: 10.1021/Ja00966A045 |
0.551 |
|
| 1965 |
Usher DA, Dennis EA, Westheimer FH. Calculation of the bond angles and conformation of methyl ethylene phosphate and related compounds Journal of the American Chemical Society. 87: 2320-2321. DOI: 10.1021/Ja01089A003 |
0.483 |
|
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