Steven M. Sparks - Publications

Affiliations: 
Viamet Pharmaceuticals 

15/31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Sparks SM, Chen CL, Martin SF. Tandem Intramolecular Benzyne-Furan Cycloadditions. Total Synthesis of Vineomycinone B(2) Methyl Ester. Tetrahedron. 63: 8619-8635. PMID 18728697 DOI: 10.1016/J.Tet.2007.04.031  0.753
2007 Martin S, Chen C, Sparks S. Synthesis of Vineomycinone B2 Methyl Ester Synfacts. 2007: 0236-0236. DOI: 10.1055/S-2007-968187  0.615
2006 Chen CL, Sparks SM, Martin SF. C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycinone B2 methyl ester. Journal of the American Chemical Society. 128: 13696-7. PMID 17044691 DOI: 10.1021/Ja0652619  0.71
2004 Sparks SM, Chow CP, Zhu L, Shea KJ. Type 2 intramolecular N-acylnitroso Diels-Alder reaction: scope and application to the synthesis of medium ring lactams. The Journal of Organic Chemistry. 69: 3025-35. PMID 15104440 DOI: 10.1021/Jo049897Z  0.812
2003 Kaelin DE, Sparks SM, Plake HR, Martin SF. Regioselective synthesis of unsymmetrical C-aryl glycosides using silicon tethers as disposable linkers. Journal of the American Chemical Society. 125: 12994-5. PMID 14570450 DOI: 10.1021/Ja0375582  0.707
2003 Sparks SM, Gutierrez AJ, Shea KJ. Preparation of perhydroisoquinolines via the intramolecular Diels-Alder reaction of N-3,5-hexadienoyl ethyl acrylimidates: a formal synthesis of (+/-)-reserpine. The Journal of Organic Chemistry. 68: 5274-85. PMID 12816489 DOI: 10.1021/Jo0341362  0.619
2002 Chow CP, Shea KJ, Sparks SM. Type 2 intramolecular N-acylnitroso diels-alder reaction: stereoselective synthesis of bridged bicyclic oxazinolactams. Organic Letters. 4: 2637-40. PMID 12153197 DOI: 10.1021/Ol026075K  0.811
2002 Chow CP, Shea KJ, Sparks SM. Type 2 intramolecular N-Acylnitroso Diels - Alder reaction: Stereoselective synthesis of bridged bicyclic oxazinolactams Organic Letters. 4: 2637-2640. DOI: 10.1021/ol026075k  0.807
2001 Sparks SM, Shea KJ. Vinyl imidates in cycloaddition reactions: a formal synthesis of (+/-)-reserpine. Organic Letters. 3: 2265-7. PMID 11463292 DOI: 10.1021/Ol015988W  0.755
2001 Bear BR, Sparks SM, Shea KJ. The Type 2 Intramolecular Diels-Alder Reaction: Synthesis and Chemistry of Bridgehead Alkenes. Angewandte Chemie (International Ed. in English). 40: 820-849. PMID 11241630 DOI: 10.1002/1521-3773(20010302)40:5<820::Aid-Anie820>3.0.Co;2-F  0.793
2001 Sparks SM, Shea KJ. Vinyl imidates in cycloaddition reactions: A formal synthesis of (±)-reserpine Organic Letters. 3: 2265-2267. DOI: 10.1021/ol015988w  0.621
2001 Bear BR, Sparks SM, Shea KJ. Intramolekulare Diels-Alder-Reaktion vom Typ 2: Synthese und Chemie von Brückenkopf-Alkenen Angewandte Chemie. 113: 864-894. DOI: 10.1002/1521-3757(20010302)113:5<864::Aid-Ange864>3.0.Co;2-0  0.703
2000 Sparks SM, Vargas JD, Shea KJ. Type 2 intramolecular nitroso Diels-Alder reaction. Synthesis and structure of bridgehead oxazinolactams. Organic Letters. 2: 1473-5. PMID 10814476 DOI: 10.1021/Ol005811M  0.746
2000 Sparks SM, Shea KJ. Vinyl imidates in cycloaddition reactions: Synthesis of (±)-alloyohimbane Tetrahedron Letters. 41: 6721-6724. DOI: 10.1016/S0040-4039(00)01093-5  0.673
2000 Sparks SM, Shea KJ. ChemInform Abstract: Vinyl Imidates in Cycloaddition Reactions: Synthesis of (.+-.)-Alloyohimbane. Cheminform. 31: no-no. DOI: 10.1002/chin.200050208  0.734
Low-probability matches (unlikely to be authored by this person)
2011 Evans KA, Shearer BG, Wisnoski DD, Shi D, Sparks SM, Sternbach DD, Winegar DA, Billin AN, Britt C, Way JM, Epperly AH, Leesnitzer LM, Merrihew RV, Xu RX, Lambert MH, et al. Phenoxyacetic acids as PPARδ partial agonists: synthesis, optimization, and in vivo efficacy. Bioorganic & Medicinal Chemistry Letters. 21: 2345-50. PMID 21414782 DOI: 10.1016/j.bmcl.2011.02.077  0.19
2009 Sparks SM, Banker P, Bickett DM, Carter HL, Clancy DC, Dickerson SH, Dwornik KA, Garrido DM, Golden PL, Nolte RT, Peat AJ, Sheckler LR, Tavares FX, Thomson SA, Wang L, et al. Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups. Bioorganic & Medicinal Chemistry Letters. 19: 976-80. PMID 19095442 DOI: 10.1016/j.bmcl.2008.11.085  0.142
2009 Sparks SM, Banker P, Bickett DM, Clancy DC, Dickerson SH, Garrido DM, Golden PL, Peat AJ, Sheckler LR, Tavares FX, Thomson SA, Weiel JE. Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues. Bioorganic & Medicinal Chemistry Letters. 19: 981-5. PMID 19095443 DOI: 10.1016/j.bmcl.2008.11.084  0.139
2016 Sparks SM, Zhou H, Generaux C, Harston L, Moncol D, Jayawickreme C, Parham J, Condreay P, Rimele T. Identification of nonabsorbable inhibitors of the scavenger receptor-BI (SR-BI) for tissue-specific administration. Bioorganic & Medicinal Chemistry Letters. PMID 26988301 DOI: 10.1016/j.bmcl.2016.03.025  0.126
2019 Sparks SM, Danger DP, Hoekstra WJ, Leesnitzer T, Schotzinger RJ, Yates CM, Becherer JD. Development of Highly Selective Pyrimidine-Based Aldosterone Synthase (CYP11B2) Inhibitors. Acs Medicinal Chemistry Letters. 10: 1056-1060. PMID 31312408 DOI: 10.1021/acsmedchemlett.9b00152  0.103
2009 Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, et al. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorganic & Medicinal Chemistry Letters. 19: 1177-82. PMID 19138846 DOI: 10.1016/j.bmcl.2008.12.085  0.095
2006 Henke BR, Sparks SM. Glycogen phosphorylase inhibitors. Mini Reviews in Medicinal Chemistry. 6: 845-57. PMID 16918491 DOI: 10.2174/138955706777934991  0.072
2014 Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S, Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele T, et al. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorganic & Medicinal Chemistry Letters. 24: 3100-3. PMID 24881566 DOI: 10.1016/j.bmcl.2014.05.012  0.066
2017 Sparks SM, Aquino C, Banker P, Collins JL, Cowan D, Diaz C, Dock ST, Hertzog DL, Liang X, Swiger ED, Yuen J, Chen G, Jayawickreme C, Moncol D, Nystrom C, et al. Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist. Bioorganic & Medicinal Chemistry Letters. PMID 28148462 DOI: 10.1016/j.bmcl.2017.01.034  0.06
2019 Sparks S, Garvey E, Hoekstra W, Schotzinger R, Becherer JD. OR09-6 Selective and Durable Suppression of Aldosterone Production in Non-Human Primates by a Novel Aldosterone Synthase Inhibitor Journal of the Endocrine Society. 3. DOI: 10.1210/JS.2019-OR09-6  0.058
2020 Pitt B, Bhatt DL, Morris K, Becherer JD, Hoekstra W, Shotzinger R, Sparks S, Lee JS. Abstract P233: Inhibition Of Aldosterone Synthesis In Non-human Primates By PB6440, The Novel Highly Selective And Potent CYP11B2 Inhibitor Hypertension. 76. DOI: 10.1161/hyp.76.suppl_1.p233  0.048
2017 Sparks SM, Spearing PK, Diaz CJ, Cowan DJ, Jayawickreme C, Chen G, Rimele TJ, Generaux C, Harston LT, Roller SG. Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration. Bioorganic & Medicinal Chemistry Letters. PMID 28916340 DOI: 10.1016/j.bmcl.2017.09.008  0.04
2020 LaScala K, Erikson M, Sparks S, Hudson S. Health Literacy Initiatives and Lessons Learned with NGOs: Wisconsin Health Literacy. Studies in Health Technology and Informatics. 269: 248-257. PMID 32593999 DOI: 10.3233/SHTI200039  0.033
2011 Martin C, Passilly-Degrace P, Sparks S, Drucker D, Besnard P. Impact of long chain fatty acids on sweet taste sensitivity in mice. Role of the GPR120/GLP-1 signaling Appetite. 57: S29. DOI: 10.1016/J.Appet.2011.05.223  0.032
2002 Lederle FA, Wilson SE, Johnson GR, Reinke DB, Littooy FN, Acher CW, Ballard DJ, Messina LM, Gordon IL, Chute EP, Krupski WC, Busuttil SJ, Barone GW, Sparks S, Graham LM, et al. Immediate repair compared with surveillance of small abdominal aortic aneurysms. The New England Journal of Medicine. 346: 1437-44. PMID 12000813 DOI: 10.1056/NEJMoa012573  0.017
2012 Martin C, Passilly-Degrace P, Chevrot M, Ancel D, Sparks SM, Drucker DJ, Besnard P. Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity. Journal of Lipid Research. 53: 2256-65. PMID 22904345 DOI: 10.1194/Jlr.M025874  0.012
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