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Wilian A. Cortopassi - Publications

Affiliations: 
2013-2017 Chemistry University of Oxford, Oxford, United Kingdom 
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Brand M, Clayton J, Moroglu M, Schiedel M, Picaud S, Bluck JP, Skwarska A, Bolland H, Chan AKN, Laurin CMC, Scorah AR, See L, Rooney TPC, Andrews KH, Fedorov O, ... ... Cortopassi WA, et al. Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Journal of Medicinal Chemistry. PMID 34255515 DOI: 10.1021/acs.jmedchem.1c00348  0.668
2019 Butler VJ, Gao F, Corrales CI, Cortopassi WA, Caballero B, Vohra M, Ashrafi K, Cuervo AM, Jacobson MP, Coppola G, Kao AW. Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response. Plos Genetics. 15: e1008295. PMID 31398187 DOI: 10.1371/Journal.Pgen.1008295  0.362
2019 Butler V, Cortopassi WA, Gururaj S, Wang AL, Pierce OM, Jacobson MP, Kao AW. Multi-granulin Domain Peptides Bind to Pro-cathepsin D and Stimulate its Enzymatic Activity in vitro. Biochemistry. PMID 31099551 DOI: 10.1021/Acs.Biochem.9B00275  0.404
2019 Charafeddine RA, Cortopassi WA, Lak P, Tan R, McKenney RJ, Jacobson MP, Barber DL, Wittmann T. Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH. The Journal of Biological Chemistry. PMID 30992364 DOI: 10.1074/Jbc.Ra118.007004  0.374
2019 Qi X, Zhang N, Zhao L, Hu L, Cortopassi WA, Jacobson MP, Li X, Zhong R. Structure-based identification of novel CK2 inhibitors with a linear 2-propenone scaffold as anti-cancer agents. Biochemical and Biophysical Research Communications. PMID 30878184 DOI: 10.1016/J.Bbrc.2019.03.016  0.339
2019 Butler VJ, Cortopassi WA, Argouarch AR, Ivry SL, Craik CS, Jacobson MP, Kao AW. Progranulin Stimulates the in vitro Maturation of pro-Cathepsin D at Acidic pH. Journal of Molecular Biology. PMID 30690031 DOI: 10.1016/J.Jmb.2019.01.027  0.342
2018 Tang S, Zhang N, Zhou Y, Cortopassi WA, Jacobson MP, Zhao LJ, Zhong RG. Structure-Based Discovery of Novel CK2α-Binding Cyclic Peptides with Anti-Cancer Activity. Molecular Informatics. PMID 30307134 DOI: 10.1002/Minf.201800089  0.412
2018 Kumar K, Woo SM, Siu T, Cortopassi WA, Duarte F, Paton RS. Cation-π interactions in protein-ligand binding: theory and data-mining reveal different roles for lysine and arginine. Chemical Science. 9: 2655-2665. PMID 29719674 DOI: 10.1039/C7Sc04905F  0.74
2017 Pliotas C, Grayer SC, Ekkerman S, Chan AK, Healy J, Marius P, Bartlett W, Khan A, Cortopassi WA, Chandler SA, Rasmussen T, Benesch JL, Paton RS, Claridge TDW, Miller S, et al. AMP binding stabilizes the KTN domain of the Shewanella denitrificans Kef potassium efflux system. Biochemistry. PMID 28656748 DOI: 10.1021/Acs.Biochem.7B00300  0.682
2016 Cortopassi WA, Kumar K, Paton RS. Cation-π interactions in CREBBP bromodomain inhibition: an electrostatic model for small-molecule binding affinity and selectivity. Organic & Biomolecular Chemistry. PMID 27814427 DOI: 10.1039/C6Ob02234K  0.747
2016 Cortopassi WA, Kumar K, Duarte F, Pimentel AS, Paton RS. Mechanisms of histone lysine-modifying enzymes: A computational perspective on the role of the protein environment. Journal of Molecular Graphics & Modelling. 67: 69-84. PMID 27258188 DOI: 10.1016/J.Jmgm.2016.04.011  0.759
2016 Brand M, Measures AR, Wilson BG, Cortopassi WA, Alexander R, Höss M, Hewings DS, Rooney TP, Paton RS, Conway SJ. Correction to Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions. Acs Chemical Biology. PMID 26756254 DOI: 10.1021/Acschembio.5B01065  0.597
2015 Cortopassi WA, Simion R, Honsby CE, França TC, Paton RS. Dioxygen Binding in the Active Site of Histone Demethylase JMJD2A and the Role of the Protein Environment. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26663343 DOI: 10.1002/chem.201504536  0.711
2015 Cortopassi WA, Simion R, Honsby CE, França TC, Paton RS. Dioxygen Binding in the Active Site of Histone Demethylase JMJD2A and the Role of the Protein Environment. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26577067 DOI: 10.1002/Chem.201502983  0.712
2015 Brand M, Measures AM, Wilson BG, Cortopassi WA, Alexander R, Höss M, Hewings DS, Rooney TP, Paton RS, Conway SJ. Small molecule inhibitors of bromodomain-acetyl-lysine interactions. Acs Chemical Biology. 10: 22-39. PMID 25549280 DOI: 10.1021/Cb500996U  0.698
2015 Cortopassi WA, Simion R, Honsby CE, França TCC, Paton RS. Cover Picture: Dioxygen Binding in the Active Site of Histone Demethylase JMJD2A and the Role of the Protein Environment (Chem. Eur. J. 52/2015) Chemistry - a European Journal. 21: 18865-18865. DOI: 10.1002/Chem.201585201  0.717
2014 Rooney TP, Filippakopoulos P, Fedorov O, Picaud S, Cortopassi WA, Hay DA, Martin S, Tumber A, Rogers CM, Philpott M, Wang M, Thompson AL, Heightman TD, Pryde DC, Cook A, et al. A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction. Angewandte Chemie (International Ed. in English). 53: 6126-30. PMID 24821300 DOI: 10.1002/Anie.201402750  0.663
2014 Cortopassi WA, Penna-Coutinho J, Aguiar AC, Pimentel AS, Buarque CD, Costa PR, Alves BR, França TC, Krettli AU. Theoretical and experimental studies of new modified isoflavonoids as potential inhibitors of topoisomerase I from Plasmodium falciparum. Plos One. 9: e91191. PMID 24651068 DOI: 10.1371/Journal.Pone.0091191  0.405
2012 Aguiar ACC, Santos RdM, Figueiredo FJB, Cortopassi WA, Pimentel AS, França TCC, Meneghetti MR, Krettli AU. Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites. Plos One. 7. PMID 22649514 DOI: 10.1371/Journal.Pone.0037259  0.349
2012 Cortopassi WA, Feital RJC, Medeiros DdJ, Guizado TRC, França TCC, Pimentel AS. Docking and molecular dynamics studies of new potential inhibitors of the human epidermal receptor 2 Molecular Simulation. 38: 1132-1142. DOI: 10.1080/08927022.2012.696113  0.311
2011 Penna-Coutinho J, Cortopassi WA, Oliveira AA, França TCC, Krettli AU. Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies Plos One. 6. PMID 21779323 DOI: 10.1371/Journal.Pone.0021237  0.356
2011 Cortopassi WA, Oliveira AA, Guimarães AP, Rennó MN, Krettli AU, França TC. Docking studies on the binding of quinoline derivatives and hematin to Plasmodium falciparum lactate dehydrogenase. Journal of Biomolecular Structure & Dynamics. 29: 207-18. PMID 21696234 DOI: 10.1080/07391102.2011.10507383  0.406
2011 Ramalho TC, França TC, Cortopassi WA, Gonçalves AS, da Silva AW, da Cunha EF. Topology and dynamics of the interaction between 5-nitroimidazole radiosensitizers and duplex DNA studied by a combination of docking, molecular dynamic simulations and NMR spectroscopy Journal of Molecular Structure. 992: 65-71. DOI: 10.1016/J.Molstruc.2011.02.042  0.358
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