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Matthew R. Lockett - Publications

Affiliations: 
Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Analytical Sensors, Surface Chemistry, Array Fabrication, Microbial Communities (Natural and Synthetic), Molecular Recognition, Protein-DNA interactions, Synthetic Biology
Website:
http://www.chem.unc.edu/people/faculty/lockett/index.html
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sitte ZR, Karlsson EE, Li H, Zhou H, Lockett MR. Continuous flow delivery system for the perfusion of scaffold-based 3D cultures. Lab On a Chip. PMID 39099241 DOI: 10.1039/d4lc00480a  0.309
2024 Sitte ZR, Karlsson EE, Larson TS, Li H, Zhou H, Lockett MR. Supported gel slab scaffolds as a three-dimensional cell-based assay platform. The Analyst. PMID 39072359 DOI: 10.1039/d4an00691g  0.305
2023 Sitte ZR, Miranda Buzetta AA, Jones SJ, Lin ZW, Whitman NA, Lockett MR. Paper-Based Coculture Platform to Evaluate the Effects of Fibroblasts on Estrogen Signaling in ER+ Breast Cancers. Acs Measurement Science Au. 3: 479-487. PMID 38145029 DOI: 10.1021/acsmeasuresciau.3c00032  0.797
2023 Sitte ZR, Larson TS, McIntosh JC, Sinanian M, Lockett MR. Selecting the appropriate indirect viability assay for 3D paper-based cultures: a data-driven study. The Analyst. PMID 37073480 DOI: 10.1039/d3an00283g  0.739
2023 Kenney RM, Lee MC, Boyce MW, Sitte ZR, Lockett MR. Cellular Invasion Assay for the Real-Time Tracking of Individual Cells in Spheroid or Tumor-like Mimics. Analytical Chemistry. PMID 36701161 DOI: 10.1021/acs.analchem.2c05201  0.786
2020 Dhar D, McKenas CG, Huang CW, Atkin JM, Dempsey JL, Lockett MR. Quantitative Effects of Disorder on Chemically Modified Amorphous Carbon Electrodes. Acs Applied Energy Materials. 3: 8038-8047. PMID 32968715 DOI: 10.1021/acsaem.0c01434  0.751
2020 McIntosh JC, Yang L, Wang T, Zhou H, Lockett MR, Oldenburg AL. Tracking the invasion of breast cancer cells in paper-based 3D cultures by OCT motility analysis. Biomedical Optics Express. 11: 3181-3194. PMID 32637249 DOI: 10.1364/Boe.382911  0.739
2020 Boyce MW, Simke WC, Kenney RM, Lockett MR. Generating linear oxygen gradients across 3D cell cultures with block-layered oxygen controlled chips (BLOCCs). Analytical Methods : Advancing Methods and Applications. 12: 18-24. PMID 32190125 DOI: 10.1039/C9Ay01690B  0.78
2020 McIntosh JC, Yang L, Wang T, Zhou H, Lockett MR, Oldenburg AL. Tracking the invasion of breast cancer cells in paper-based 3D cultures by OCT motility analysis Biomedical Optics Express. 11: 3181. DOI: 10.1364/boe.382911  0.705
2019 Tobias F, Mcintosh JC, LaBonia GJ, Boyce MW, Lockett MR, Hummon AB. Developing a Drug Screening Platform: MALDI-Mass Spectrometry Imaging of Paper-Based Cultures. Analytical Chemistry. PMID 31755703 DOI: 10.1021/Acs.Analchem.9B03536  0.785
2019 Cramer SM, Larson TS, Lockett MR. Tissue Papers: Leveraging paper-based microfluidics for the next generation of 3D tissue models. Analytical Chemistry. PMID 31356054 DOI: 10.1021/Acs.Analchem.9B02102  0.344
2019 Whitman NA, Lin ZW, Kenney RM, Albertini L, Lockett MR. Hypoxia differentially regulates estrogen receptor alpha in 2D and 3D culture formats. Archives of Biochemistry and Biophysics. PMID 31163125 DOI: 10.1016/J.Abb.2019.05.025  0.768
2019 Fehr JM, McKenas CG, Liu B, Lockett MR. Azide‑alkyne click reactions to prepare chemically modified amorphous carbon electrodes Applied Surface Science. 480: 1109-1115. DOI: 10.1016/J.Apsusc.2019.02.151  0.764
2018 Kenney RM, Loeser A, Whitman NA, Lockett MR. Paper-based Transwell assays: an inexpensive alternative to study cellular invasion. The Analyst. PMID 30328422 DOI: 10.1039/C8An01157E  0.782
2018 Whitman NA, Lin ZW, DiProspero TJ, McIntosh JC, Lockett MR. Screening Estrogen Receptor Modulators in a Paper-Based Breast Cancer Model. Analytical Chemistry. PMID 30226366 DOI: 10.1021/Acs.Analchem.8B02486  0.775
2018 Kenney RM, Boyce MW, Whitman N, Kromhout BP, Lockett MR. A pH-sensing optode for mapping spatiotemporal gradients in 3D paper-based cell cultures. Analytical Chemistry. PMID 29323486 DOI: 10.1021/Acs.Analchem.7B05015  0.761
2018 McKenas CG, Fehr JM, Liu B, Donley CL, Lockett MR. Mechanistic Insights into UV-Initiated Thiol–Ene Reactions on Amorphous Carbon Films The Journal of Physical Chemistry C. 122: 21854-21860. DOI: 10.1021/Acs.Jpcc.8B04359  0.766
2017 Boyce MW, LaBonia GJ, Hummon AB, Lockett MR. Assessing chemotherapeutic effectiveness using a paper-based tumor model. The Analyst. PMID 28702529 DOI: 10.1039/C7An00806F  0.748
2017 Lloyd CC, Boyce MW, Lockett MR. Paper-based Invasion Assays for Quantifying Cellular Movement in Three-dimensional Tissue-like Structures. Current Protocols in Chemical Biology. 9: 75-95. PMID 28628202 DOI: 10.1002/Cpch.22  0.747
2017 Kenney RM, Lloyd CC, Whitman NA, Lockett MR. 3D cellular invasion platforms: how do paper-based cultures stack up? Chemical Communications (Cambridge, England). PMID 28621775 DOI: 10.1039/C7Cc02357J  0.787
2016 McKenas CG, Fehr JM, Donley CL, Lockett MR. Thiol-ene modified amorphous carbon substrates: surface patterning and chemically modified electrode preparation. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27657877 DOI: 10.1021/Acs.Langmuir.6B02961  0.772
2016 Truong AS, Lockett MR. Oxygen as a chemoattractant: confirming cellular hypoxia in paper-based invasion assays. The Analyst. PMID 27138213 DOI: 10.1039/C6An00630B  0.385
2016 Simon KA, Mosadegh B, Minn KT, Lockett MR, Mohammady MR, Boucher DM, Hall AB, Hillier SM, Udagawa T, Eustace BK, Whitesides GM. Metabolic response of lung cancer cells to radiation in a paper-based 3D cell culture system. Biomaterials. 95: 47-59. PMID 27116031 DOI: 10.1016/J.Biomaterials.2016.03.002  0.479
2016 Whitman NA, McIntosh JC, Penley JB, Lockett MR. Microfabricated Devices for Studying the Metabolism and Cytotoxicity of Drug Candidates. Current Pharmaceutical Biotechnology. PMID 26927213 DOI: 10.2174/1389201017666160301103648  0.758
2015 Boyce MW, Kenney RM, Truong AS, Lockett MR. Quantifying oxygen in paper-based cell cultures with luminescent thin film sensors. Analytical and Bioanalytical Chemistry. PMID 26667655 DOI: 10.1007/S00216-015-9189-X  0.793
2015 Kenney RM, Boyce MW, Truong AS, Bagnell CR, Lockett MR. Real-time imaging of cancer cell chemotaxis in paper-based scaffolds. The Analyst. PMID 26548584 DOI: 10.1039/C5An01787D  0.801
2015 Truong AS, Lochbaum CA, Boyce MW, Lockett MR. Tracking the Invasion of Small Numbers of Cells in Paper-Based Assays with Quantitative PCR. Analytical Chemistry. PMID 26507077 DOI: 10.1021/Acs.Analchem.5B02362  0.732
2015 Lockett MR, Smith LM. Carbon Substrates: A Stable Foundation for Biomolecular Arrays. Annual Review of Analytical Chemistry (Palo Alto, Calif.). PMID 26048550 DOI: 10.1146/Annurev-Anchem-071114-040146  0.519
2015 Mosadegh B, Lockett MR, Minn KT, Simon KA, Gilbert K, Hillier S, Newsome D, Li H, Hall AB, Boucher DM, Eustace BK, Whitesides GM. A paper-based invasion assay: assessing chemotaxis of cancer cells in gradients of oxygen. Biomaterials. 52: 262-71. PMID 25818432 DOI: 10.1016/J.Biomaterials.2015.02.012  0.498
2015 Fox JM, Kang K, Sherman W, Héroux A, Sastry GM, Baghbanzadeh M, Lockett MR, Whitesides GM. Interactions between Hofmeister anions and the binding pocket of a protein. Journal of the American Chemical Society. 137: 3859-66. PMID 25738615 DOI: 10.1021/Jacs.5B00187  0.38
2014 Yoon HJ, Liao KC, Lockett MR, Kwok SW, Baghbanzadeh M, Whitesides GM. Rectification in tunneling junctions: 2,2'-bipyridyl-terminated n-alkanethiolates. Journal of the American Chemical Society. 136: 17155-62. PMID 25389953 DOI: 10.1021/Ja509110A  0.735
2014 Mosadegh B, Dabiri BE, Lockett MR, Derda R, Campbell P, Parker KK, Whitesides GM. Three-dimensional paper-based model for cardiac ischemia. Advanced Healthcare Materials. 3: 1036-43. PMID 24574054 DOI: 10.1002/Adhm.201300575  0.669
2014 Snyder PW, Lockett MR, Moustakas DT, Whitesides GM. Is it the shape of the cavity, or the shape of the water in the cavity? European Physical Journal: Special Topics. 223: 853-891. DOI: 10.1140/Epjst/E2013-01818-Y  0.392
2013 Breiten B, Lockett MR, Sherman W, Fujita S, Al-Sayah M, Lange H, Bowers CM, Heroux A, Krilov G, Whitesides GM. Water networks contribute to enthalpy/entropy compensation in protein-ligand binding. Journal of the American Chemical Society. 135: 15579-84. PMID 24044696 DOI: 10.1021/Ja4075776  0.377
2013 Derda R, Lockett MR, Tang SK, Fuller RC, Maxwell EJ, Breiten B, Cuddemi CA, Ozdogan A, Whitesides GM. Filter-based assay for Escherichia coli in aqueous samples using bacteriophage-based amplification. Analytical Chemistry. 85: 7213-20. PMID 23848541 DOI: 10.1021/Ac400961B  0.64
2013 Lockett MR, Lange H, Breiten B, Heroux A, Sherman W, Rappoport D, Yau PO, Snyder PW, Whitesides GM. The binding of benzoarylsulfonamide ligands to human carbonic anhydrase is insensitive to formal fluorination of the ligand. Angewandte Chemie (International Ed. in English). 52: 7714-7. PMID 23788494 DOI: 10.1002/Anie.201301813  0.362
2013 Broderick AH, Carter MC, Lockett MR, Smith LM, Lynn DM. Fabrication of oligonucleotide and protein arrays on rigid and flexible substrates coated with reactive polymer multilayers. Acs Applied Materials & Interfaces. 5: 351-9. PMID 23237360 DOI: 10.1021/Am302285N  0.512
2013 Lockett MR, Mirica KA, Mace CR, Blackledge RD, Whitesides GM. Analyzing forensic evidence based on density with magnetic levitation. Journal of Forensic Sciences. 58: 40-5. PMID 22804094 DOI: 10.1111/J.1556-4029.2012.02221.X  0.739
2012 Broderick AH, Lockett MR, Buck ME, Yuan Y, Smith LM, Lynn DM. In situ Synthesis of Oligonucleotide Arrays on Surfaces Coated with Crosslinked Polymer Multilayers. Chemistry of Materials : a Publication of the American Chemical Society. 24: 939-945. PMID 22611305 DOI: 10.1021/Cm202720Q  0.515
2012 Wu CH, Lockett MR, Smith LM. RNA-mediated gene assembly from DNA arrays. Angewandte Chemie (International Ed. in English). 51: 4628-32. PMID 22473711 DOI: 10.1002/Anie.201109058  0.588
2012 Mirica KA, Lockett MR, Snyder PW, Shapiro ND, Mack ET, Nam S, Whitesides GM. Selective precipitation and purification of monovalent proteins using oligovalent ligands and ammonium sulfate. Bioconjugate Chemistry. 23: 293-9. PMID 22188202 DOI: 10.1021/Bc200390Q  0.657
2011 Snyder PW, Mecinovic J, Moustakas DT, Thomas SW, Harder M, Mack ET, Lockett MR, Héroux A, Sherman W, Whitesides GM. Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proceedings of the National Academy of Sciences of the United States of America. 108: 17889-94. PMID 22011572 DOI: 10.1073/Pnas.1114107108  0.64
2011 Olson CN, Galloway MM, Yu G, Hedman CJ, Lockett MR, Yoon T, Stone EA, Smith LM, Keutsch FN. Hydroxycarboxylic acid-derived organosulfates: synthesis, stability, and quantification in ambient aerosol. Environmental Science & Technology. 45: 6468-74. PMID 21682266 DOI: 10.1021/Es201039P  0.429
2011 Olson CN, Galloway MM, Yu G, Hedman CJ, Lockett MR, Yoon TP, Stone EA, Smith LM, Keutsch FN. Reply to comment on "hydroxycarboxylic acid-derived organosulfates: Synthesis, stability and quantification in ambient aerosol" Environmental Science and Technology. 45: 9111. DOI: 10.1021/Es203122Z  0.425
2010 Lockett MR, Smith LM. Halogenation of carbon substrates for increased reactivity with alkenes. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 16642-6. PMID 20925329 DOI: 10.1021/La103050Z  0.5
2010 Lockett MR, Smith LM. The Formation and Stability of Alkylthiol Monolayers on Carbon Substrates. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 114: 12635-12641. PMID 20706614 DOI: 10.1021/Jp102821X  0.518
2009 Lockett MR, Smith LM. Fabrication and characterization of DNA arrays prepared on carbon-on-metal substrates. Analytical Chemistry. 81: 6429-37. PMID 20020675 DOI: 10.1021/Ac900807Q  0.494
2009 Mandir JB, Lockett MR, Phillips MF, Allawi HT, Lyamichev VI, Smith LM. Rapid determination of RNA accessible sites by surface plasmon resonance detection of hybridization to DNA arrays. Analytical Chemistry. 81: 8949-56. PMID 19874056 DOI: 10.1021/Ac9015962  0.706
2009 Lockett MR, Smith LM. Attaching molecules to chlorinated and brominated amorphous carbon substrates via Grignard reactions. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 3340-3. PMID 19708232 DOI: 10.1021/la8039626  0.462
2009 Lockett MR, Carlisle JC, Le DV, Smith LM. Acyl chloride-modified amorphous carbon substrates for the attachment of alcohol-, thiol-, and amine-containing molecules. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 5120-6. PMID 19317418 DOI: 10.1021/La804140R  0.523
2009 Lockett MR, Smith LM. Attaching Molecules to Chlorinated and Brominated Amorphous Carbon Substrates via Grignard Reactions. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 3340-3343. PMID 19209862 DOI: 10.1021/La8039626  0.525
2008 Lockett MR, Shortreed MR, Smith LM. Aldehyde-terminated amorphous carbon substrates for the fabrication of biomolecule arrays. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 9198-203. PMID 18672922 DOI: 10.1021/La800991T  0.529
2008 Lockett MR, Weibel SC, Phillips MF, Shortreed MR, Sun B, Corn RM, Hamers RJ, Cerrina F, Smith LM. Carbon-on-metal films for surface plasmon resonance detection of DNA arrays. Journal of the American Chemical Society. 130: 8611-3. PMID 18597426 DOI: 10.1021/Ja802454C  0.719
2008 Phillips MF, Lockett MR, Rodesch MJ, Shortreed MR, Cerrina F, Smith LM. In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication. Nucleic Acids Research. 36: e7. PMID 18084027 DOI: 10.1093/Nar/Gkm1103  0.716
2008 Lockett MR, Phillips MF, Jarecki JL, Peelen D, Smith LM. A tetrafluorophenyl activated ester self-assembled monolayer for the immobilization of amine-modified oligonucleotides. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 69-75. PMID 18047381 DOI: 10.1021/La702493U  0.703
2007 Lee JE, Didier DN, Lockett MR, Scalf M, Greene AS, Olivier M, Smith LM. Characterization of vascular endothelial growth factor receptors on the endothelial cell surface during hypoxia using whole cell binding arrays. Analytical Biochemistry. 369: 241-7. PMID 17624292 DOI: 10.1016/J.Ab.2007.06.010  0.676
2007 Lockett MR, Shortreed MR, Smith LM. Molecular beacon-style hybridization assay for quantitative analysis of surface invasive cleavage reactions. Analytical Chemistry. 79: 6031-6. PMID 17595056 DOI: 10.1021/Ac070424C  0.519
2006 Sun B, Colavita PE, Kim H, Lockett M, Marcus MS, Smith LM, Hamers RJ. Covalent photochemical functionalization of amorphous carbon thin films for integrated real-time biosensing. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 9598-605. PMID 17073485 DOI: 10.1021/La061749B  0.524
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