Carolyn Worby - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Worby CA, Mayfield JE, Pollak AJ, Dixon JE, Banerjee S. The ABCs of the atypical Fam20 secretory pathway kinases. The Journal of Biological Chemistry. 296: 100267. PMID 33759783 DOI: 10.1016/j.jbc.2021.100267  0.533
2019 Gerson-Gurwitz A, Worby CA, Lee KY, Khaliullin R, Bouffard J, Cheerambathur D, Oegema K, Cram EJ, Dixon JE, Desai A. Ancestral roles of the Fam20C family of secreted protein kinases revealed in . The Journal of Cell Biology. PMID 31541016 DOI: 10.1083/Jcb.201807041  0.526
2019 Worby CA, Dixon JE. Reversible phosphorylation: a birthday tribute to Herb Tabor. The Journal of Biological Chemistry. 294: 1638-1642. PMID 30710011 DOI: 10.1074/Jbc.Tme118.004161  0.441
2015 Sanyal A, Chen AJ, Nakayasu ES, Lazar CS, Zbornik EA, Worby CA, Koller A, Mattoo S. A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response. The Journal of Biological Chemistry. 290: 8482-99. PMID 25601083 DOI: 10.1074/Jbc.M114.618348  0.324
2014 Worby CA, Dixon JE. Unpacking the unfolded protein response. Cell. 158: 1221-4. PMID 25215479 DOI: 10.1016/J.Cell.2014.08.025  0.446
2014 Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE, Xiao J, Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon JE, Yeo CY, Whitman M. A secreted tyrosine kinase acts in the extracellular environment. Cell. 158: 1033-44. PMID 25171405 DOI: 10.1016/J.Cell.2014.06.048  0.58
2014 Worby CA, Dixon JE. PTEN. Annual Review of Biochemistry. 83: 641-69. PMID 24905788 DOI: 10.1146/annurev-biochem-082411-113907  0.458
2013 Teh PG, Chen MJ, Engel JL, Worby CA, Manning G, Dixon JE, Zhang J. Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica. The Journal of Biological Chemistry. 288: 5176-85. PMID 23293031 DOI: 10.1074/Jbc.M112.413617  0.482
2012 Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon JE. Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science (New York, N.Y.). 336: 1150-3. PMID 22582013 DOI: 10.1126/Science.1217817  0.54
2012 Geertsema RS, Worby C, Kruger RP, Tagawa Y, Russo R, Herdman DS, Lo K, Kimball RA, Dixon J, Corbeil LB. Corrigendum to "Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits" [Vaccine 26 (2008) 4506-4512] Vaccine. 30: 4578. DOI: 10.1016/J.Vaccine.2012.04.061  0.458
2011 Mattoo S, Durrant E, Chen MJ, Xiao J, Lazar CS, Manning G, Dixon JE, Worby CA. Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. The Journal of Biological Chemistry. 286: 32834-42. PMID 21795713 DOI: 10.1074/Jbc.M111.227603  0.52
2011 Romá-Mateo C, Solaz-Fuster Mdel C, Gimeno-Alcañiz JV, Dukhande VV, Donderis J, Worby CA, Marina A, Criado O, Koller A, Rodriguez De Cordoba S, Gentry MS, Sanz P. Laforin, a dual-specificity phosphatase involved in Lafora disease, is phosphorylated at Ser25 by AMP-activated protein kinase. The Biochemical Journal. 439: 265-75. PMID 21728993 DOI: 10.1042/Bj20110150  0.365
2011 Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metabolism. 13: 690-700. PMID 21641550 DOI: 10.1016/J.Cmet.2011.04.007  0.458
2011 Worby CA, Dixon JE. Glycogen synthase: an old enzyme with a new trick. Cell Metabolism. 13: 233-4. PMID 21356510 DOI: 10.1016/J.Cmet.2011.02.006  0.448
2010 Xiao J, Worby CA, Mattoo S, Sankaran B, Dixon JE. Structural basis of Fic-mediated adenylylation. Nature Structural & Molecular Biology. 17: 1004-10. PMID 20622875 DOI: 10.1038/Nsmb.1867  0.503
2010 Zekarias B, Mattoo S, Worby C, Lehmann J, Rosenbusch RF, Corbeil LB. Histophilus somni IbpA DR2/Fic in virulence and immunoprotection at the natural host alveolar epithelial barrier. Infection and Immunity. 78: 1850-8. PMID 20176790 DOI: 10.1128/Iai.01277-09  0.346
2009 Gentry MS, Dixon JE, Worby CA. Lafora disease: insights into neurodegeneration from plant metabolism. Trends in Biochemical Sciences. 34: 628-39. PMID 19818631 DOI: 10.1016/J.Tibs.2009.08.002  0.452
2009 Worby CA, Mattoo S, Kruger RP, Corbeil LB, Koller A, Mendez JC, Zekarias B, Lazar C, Dixon JE. The fic domain: regulation of cell signaling by adenylylation. Molecular Cell. 34: 93-103. PMID 19362538 DOI: 10.1016/J.Molcel.2009.03.008  0.505
2008 Geertsema RS, Worby C, Kruger RP, Tagawa Y, Russo R, Herdman DS, Lo K, Kimball RA, Dixon J, Corbeil LB. Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits. Vaccine. 26: 4506-12. PMID 18590787 DOI: 10.1016/J.Vaccine.2008.06.046  0.504
2008 Iwasaki H, Murata Y, Kim Y, Hossain MI, Worby CA, Dixon JE, McCormack T, Sasaki T, Okamura Y. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proceedings of the National Academy of Sciences of the United States of America. 105: 7970-5. PMID 18524949 DOI: 10.1073/Pnas.0803936105  0.45
2008 Worby CA, Gentry MS, Dixon JE. Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). The Journal of Biological Chemistry. 283: 4069-76. PMID 18070875 DOI: 10.1074/Jbc.M708712200  0.537
2007 Cheng A, Zhang M, Gentry MS, Worby CA, Dixon JE, Saltiel AR. A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes & Development. 21: 2399-409. PMID 17908927 DOI: 10.1101/Gad.1553207  0.472
2007 Gentry MS, Dowen RH, Worby CA, Mattoo S, Ecker JR, Dixon JE. The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. The Journal of Cell Biology. 178: 477-88. PMID 17646401 DOI: 10.1083/Jcb.200704094  0.464
2006 Worby CA, Gentry MS, Dixon JE. Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. The Journal of Biological Chemistry. 281: 30412-8. PMID 16901901 DOI: 10.1074/Jbc.M606117200  0.539
2006 Worby CA, Dixon JE. Microbiology. Bacteria seize control by acetylating host proteins. Science (New York, N.Y.). 312: 1150-1. PMID 16731519 DOI: 10.1126/Science.1128785  0.476
2005 Worby CA, Dixon JE. Phosphoinositide phosphatases: emerging roles as voltage sensors? Molecular Interventions. 5: 274-7. PMID 16249522 DOI: 10.1124/Mi.5.5.5  0.418
2005 Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon JE. Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Molecular Cell. 19: 197-207. PMID 16039589 DOI: 10.1016/J.Molcel.2005.06.008  0.469
2005 Gentry MS, Worby CA, Dixon JE. Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proceedings of the National Academy of Sciences of the United States of America. 102: 8501-6. PMID 15930137 DOI: 10.1073/Pnas.0503285102  0.474
2004 Worby CA, Dixon JE. RNA interference in cultured Drosophila cells. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 26.5. PMID 18265350 DOI: 10.1002/0471142727.Mb2605S65  0.429
2004 Pagliarini DJ, Worby CA, Dixon JE. A PTEN-like phosphatase with a novel substrate specificity. The Journal of Biological Chemistry. 279: 38590-6. PMID 15247229 DOI: 10.1074/Jbc.M404959200  0.521
2002 Worby CA, Dixon JE. Sorting out the cellular functions of sorting nexins. Nature Reviews. Molecular Cell Biology. 3: 919-31. PMID 12461558 DOI: 10.1038/Nrm974  0.495
2002 Muda M, Worby CA, Simonson-Leff N, Clemens JC, Dixon JE. Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. The Biochemical Journal. 366: 73-7. PMID 12014990 DOI: 10.1042/Bj20020298  0.551
2002 Worby CA, Simonson-Leff N, Clemens JC, Huddler D, Muda M, Dixon JE. Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. The Journal of Biological Chemistry. 277: 9422-8. PMID 11773052 DOI: 10.1074/Jbc.M110172200  0.539
2001 Worby CA, Simonson-Leff N, Dixon JE. RNA interference of gene expression (RNAi) in cultured Drosophila cells Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001: PL1. PMID 11752672 DOI: 10.1126/Stke.2001.95.Pl1  0.429
2001 Worby CA, Simonson-Leff N, Clemens JC, Kruger RP, Muda M, Dixon JE. The Sorting Nexin, DSH3PX1, Connects the Axonal Guidance Receptor, Dscam, to the Actin Cytoskeleton Journal of Biological Chemistry. 276: 41782-41789. PMID 11546816 DOI: 10.1074/Jbc.M107080200  0.517
2000 Worby C, Margolis B. Positive versus negative signaling of LET-23: regulation through the adaptor protein, SEM-5. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe2. PMID 11752629 DOI: 10.1126/Stke.2000.63.Pe2  0.376
2000 Toth EA, Worby C, Dixon JE, Goedken ER, Marqusee S, Yeates TO. The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds. Journal of Molecular Biology. 301: 433-50. PMID 10926519 DOI: 10.1006/Jmbi.2000.3970  0.539
2000 Schmucker D, Clemens JC, Shu H, Worby CA, Xiao J, Muda M, Dixon JE, Zipursky SL. Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell. 101: 671-84. PMID 10892653 DOI: 10.1016/S0092-8674(00)80878-8  0.457
2000 Clemens JC, Worby CA, Simonson-Leff N, Muda M, Maehama T, Hemmings BA, Dixon JE. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways Proceedings of the National Academy of Sciences of the United States of America. 97: 6499-6503. PMID 10823906 DOI: 10.1073/Pnas.110149597  0.532
1999 Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF. His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis. Biochemistry. 38: 22-32. PMID 9890879 DOI: 10.1021/Bi982299S  0.512
1998 Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF. Implication of His68 in the substrate site of Bacillus subtilis adenylosuccinate lyase by mutagenesis and affinity labeling with 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-monophosphate. Biochemistry. 37: 8481-9. PMID 9622500 DOI: 10.1021/Bi9805339  0.514
1998 Worby CA, Vega QC, Chao HHJ, Seasholtz AF, Thompson RC, Dixon JE. Identification and characterization of GFRα-3, a novel co-receptor belonging to the glial cell line-derived neurotrophic receptor family Journal of Biological Chemistry. 273: 3502-3508. PMID 9452475 DOI: 10.1074/Jbc.273.6.3502  0.446
1997 Lee TT, Worby C, Dixon JE, Colman RF. Identification of His141 in the active site of Bacillus subtilis adenylosuccinate lyase by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate. The Journal of Biological Chemistry. 272: 458-65. PMID 8995283 DOI: 10.1074/Jbc.272.1.458  0.502
1996 Vega QC, Worby CA, Lechner MS, Dixon JE, Dressler GR. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 10657-61. PMID 8855235 DOI: 10.1073/Pnas.93.20.10657  0.484
1996 Worby CA, Vega QC, Zhao Y, Chao HHJ, Seasholtz AF, Dixon JE. Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase Journal of Biological Chemistry. 271: 23619-23622. PMID 8798576 DOI: 10.1074/Jbc.271.39.23619  0.475
1996 Liu X, Vega QC, Decker RA, Pandey A, Worby CA, Dixon JE. Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities. The Journal of Biological Chemistry. 271: 5309-12. PMID 8621380 DOI: 10.1074/Jbc.271.10.5309  0.48
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