Year |
Citation |
Score |
2024 |
Asano Y, Veatch J, McAfee M, Bakhtiari J, Lee B, Martin L, Zhang S, Mazziotta F, Paulson KG, Schmitt TM, Munkbhat A, Young C, Seaton B, Hunter D, Horst N, ... ... Greenberg PD, et al. Tumor Regression Following Engineered Polyomavirus-Specific T Cell Therapy in Immune Checkpoint Inhibitor-Refractory Merkel Cell Carcinoma. Medrxiv : the Preprint Server For Health Sciences. PMID 39006423 DOI: 10.1101/2024.07.01.24309780 |
0.851 |
|
2024 |
Shasha C, Glass DR, Moelhman E, Islas L, Tian Y, Szeto GL, Peng T, Song X, Wurscher M, Bumol TF, Torgerson TR, Greenberg PD, Green DJ, Newell EW. Hallmarks of tumor-experienced T cells are absent in multiple myeloma patients from diagnosis through maintenance therapy. Biorxiv : the Preprint Server For Biology. PMID 38895348 DOI: 10.1101/2024.06.03.597178 |
0.519 |
|
2024 |
Krakow EF, Brault M, Summers C, Cunningham TM, Biernacki MA, Black RG, Woodward KB, Vartanian N, Kanaan SB, Yeh AC, Dossa RG, Bar M, Cassaday RD, Dahlberg A, Till BG, ... ... Greenberg PD, et al. HA-1-targeted T cell receptor (TCR) T cell therapy for recurrent leukemia after hematopoietic stem cell transplantation. Blood. PMID 38683966 DOI: 10.1182/blood.2024024105 |
0.539 |
|
2023 |
Martinov T, Greenberg PD. Targeting Driver Oncogenes and Other Public Neoantigens Using T Cell Receptor-Based Cellular Therapy. Annual Review of Cancer Biology. 7: 331-351. PMID 37655310 DOI: 10.1146/annurev-cancerbio-061521-082114 |
0.512 |
|
2023 |
Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, ... ... Greenberg PD, et al. Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications Biology. 6: 528. PMID 37193826 DOI: 10.1038/s42003-023-04899-8 |
0.807 |
|
2023 |
Nava Lauson CB, Tiberti S, Corsetto PA, Conte F, Tyagi P, Machwirth M, Ebert S, Loffreda A, Scheller L, Sheta D, Mokhtari Z, Peters T, Raman AT, Greco F, Rizzo AM, ... ... Greenberg PD, et al. Linoleic acid potentiates CD8 T cell metabolic fitness and antitumor immunity. Cell Metabolism. PMID 36898381 DOI: 10.1016/j.cmet.2023.02.013 |
0.453 |
|
2022 |
Heath J, Chour W, Choi J, Xie J, Chaffee M, Schmitt T, Finton K, Delucia D, Xu A, Su Y, Chen D, Zhang R, Yuan D, Hong S, Ng A, ... ... Greenberg P, et al. Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis. Research Square. PMID 36415462 DOI: 10.21203/rs.3.rs-1090664/v1 |
0.815 |
|
2022 |
Anderson KG, Oda SK, Bates BM, Burnett MG, Rodgers Suarez M, Ruskin SL, Greenberg PD. Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy. Journal For Immunotherapy of Cancer. 10. PMID 35264436 DOI: 10.1136/jitc-2021-003959 |
0.779 |
|
2022 |
Su Y, Yuan D, Chen DG, Ng RH, Wang K, Choi J, Li S, Hong S, Zhang R, Xie J, Kornilov SA, Scherler K, Pavlovitch-Bedzyk AJ, Dong S, Lausted C, ... ... Greenberg PD, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. PMID 35216672 DOI: 10.1016/j.cell.2022.01.014 |
0.793 |
|
2022 |
Stromnes IM, Hulbert A, Rollins MR, Basom RS, Delrow J, Bonson P, Burrack AL, Hingorani SR, Greenberg PD. Insufficiency of compound immune checkpoint blockade to overcome engineered T cell exhaustion in pancreatic cancer. Journal For Immunotherapy of Cancer. 10. PMID 35210305 DOI: 10.1136/jitc-2021-003525 |
0.861 |
|
2022 |
Lahman MC, Schmitt TM, Paulson KG, Vigneron N, Buenrostro D, Wagener FD, Voillet V, Martin L, Gottardo R, Bielas J, McElrath JM, Stirewalt DL, Pogosova-Agadjanyan EL, Yeung CC, Pierce RH, ... ... Greenberg PD, et al. Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency. Science Translational Medicine. 14: eabg8070. PMID 35138909 DOI: 10.1126/scitranslmed.abg8070 |
0.836 |
|
2021 |
Lee JW, Su Y, Baloni P, Chen D, Pavlovitch-Bedzyk AJ, Yuan D, Duvvuri VR, Ng RH, Choi J, Xie J, Zhang R, Murray K, Kornilov S, Smith B, Magis AT, ... ... Greenberg PD, et al. Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nature Biotechnology. PMID 34489601 DOI: 10.1038/s41587-021-01020-4 |
0.727 |
|
2020 |
Morse CB, Voillet V, Bates BM, Chiu EY, Garcia NM, Gottardo R, Greenberg PD, Anderson KG. Development of a clinically relevant ovarian cancer model incorporating surgical cytoreduction to evaluate treatment of micro-metastatic disease. Gynecologic Oncology. PMID 33229044 DOI: 10.1016/j.ygyno.2020.11.009 |
0.655 |
|
2020 |
Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, Scherler K, Troisch P, Baloni P, Qin G, Smith B, Kornilov SA, Rostomily C, ... ... Greenberg PD, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. PMID 33171100 DOI: 10.1016/j.cell.2020.10.037 |
0.785 |
|
2020 |
Oda SK, Anderson KG, Ravikumar P, Bonson P, Garcia NM, Jenkins CM, Zhuang S, Daman AW, Chiu EY, Bates BM, Greenberg PD. A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy. The Journal of Experimental Medicine. 217. PMID 32860705 DOI: 10.1084/Jem.20191166 |
0.799 |
|
2020 |
Manzo T, Prentice BM, Anderson KG, Raman A, Schalck A, Codreanu GS, Nava Lauson CB, Tiberti S, Raimondi A, Jones MA, Reyzer M, Bates BM, Spraggins JM, Patterson NH, McLean JA, ... ... Greenberg PD, et al. Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells. The Journal of Experimental Medicine. 217. PMID 32491160 DOI: 10.1084/Jem.20191920 |
0.79 |
|
2019 |
Anderson KG, Voillet V, Bates B, Chiu EY, Burnett MG, Garcia NM, Oda SK, Morse CB, Stromnes IM, Drescher CW, Gottardo R, Greenberg PD. Engineered adoptive T-cell therapy prolongs survival in a preclinical model of advanced stage ovarian cancer. Cancer Immunology Research. PMID 31337659 DOI: 10.1158/2326-6066.Cir-19-0258 |
0.874 |
|
2019 |
Chapuis AG, Egan DN, Bar M, Schmitt TM, McAfee MS, Paulson KG, Voillet V, Gottardo R, Ragnarsson GB, Bleakley M, Yeung CC, Muhlhauser P, Nguyen HN, Kropp LA, Castelli L, ... ... Greenberg PD, et al. T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant. Nature Medicine. PMID 31235963 DOI: 10.1038/S41591-019-0472-9 |
0.828 |
|
2019 |
Stromnes IM, Burrack AL, Hulbert A, Bonson P, Black C, Brockenbrough JS, Raynor JF, Spartz EJ, Pierce RH, Greenberg PD, Hingorani SR. Differential effects of depleting versus programming tumor-associated macrophages on engineered T cells in pancreatic ductal adenocarcinoma. Cancer Immunology Research. PMID 31028033 DOI: 10.1158/2326-6066.Cir-18-0448 |
0.819 |
|
2019 |
Anderson KG, Egan D, Hingorani SR, Oda SK, Paulson K, Perret R, Schmidt L, Schmitt T, Stromnes I, Chapuis A, Greenberg PD. Abstract IA17: Utilizing synthetic biology and high-dimensional probing to address therapeutic obstacles and empower engineered T cells with the capacity to eradicate tumors Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Ia17 |
0.819 |
|
2019 |
Anderson KG, Burnett MG, Voillet V, Chiu EY, Bates BM, Garcia NM, Gottado R, Greenberg PD. Abstract 3208: Using T cell engineering plus triple checkpoint blockade to enhance the efficacy of adoptive immunotherapy in ovarian cancer Immunology. DOI: 10.1158/1538-7445.Sabcs18-3208 |
0.488 |
|
2019 |
Greenberg PD, Anderson KG, Egan D, Hingorani SR, Nezi L, Manzo T, Oda SK, Paulson KG, Perret R, Schmidt L, Schmitt TM, Stromnes IM, Chapuis AG. Abstract I11: Targeting pancreatic cancer with TCR-engineered T cells Immunology. 79. DOI: 10.1158/1538-7445.Panca19-I11 |
0.766 |
|
2018 |
Paulson KG, Voillet V, McAfee MS, Hunter DS, Wagener FD, Perdicchio M, Valente WJ, Koelle SJ, Church CD, Vandeven N, Thomas H, Colunga AG, Iyer JG, Yee C, Kulikauskas R, ... ... Greenberg PD, et al. Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA. Nature Communications. 9: 3868. PMID 30250229 DOI: 10.1038/S41467-018-06300-3 |
0.828 |
|
2018 |
Greenberg PD, Anderson KG, Egan D, Hingorani SR, Oda SK, Perret R, Schmitt TM, Stromnes IM, Schmidt L, Chapuis AG. Abstract IA02: Engineering T cells to eradicate tumors in the age of synthetic biology Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia02 |
0.837 |
|
2018 |
Morse CB, Anderson KG, Bates BM, Chiu EY, Garcia NM, Greenberg PD. Abstract A57: Adoptive T cell therapy for ovarian cancer: Application of a surgically relevant model Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A57 |
0.587 |
|
2018 |
Schmitt TM, McAfee M, Robins H, Kropp L, Greenberg PD, Chapuis AG. Abstract A51: High-throughput method identifies rare, high-affinity, thymus-vetted T cell receptors (TCRs) for clinical translation Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A51 |
0.639 |
|
2018 |
Paulson KG, Schmitt TM, Egan D, Voillet V, Lahman MC, Wagener FD, Hunter DS, Muhlhauser PR, Hendrie PC, Yeung C, Vigneron N, Eynde BVd, Bielas JH, Bar M, Gottardo R, ... ... Greenberg PD, et al. Abstract 2980: Single cell RNA sequencing reveals AML immunoediting under pressure from engineered T cell therapy Cancer Research. 78: 2980-2980. DOI: 10.1158/1538-7445.Am2018-2980 |
0.629 |
|
2018 |
Anderson K, Oda S, Bates B, Chiu E, Morse C, Garcia N, Greenberg P. Abstract 2555: Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in solid tumors Cancer Research. 78: 2555-2555. DOI: 10.1158/1538-7445.Am2018-2555 |
0.602 |
|
2017 |
Harris DT, Hager MV, Smith SN, Cai Q, Stone JD, Kruger P, Lever M, Dushek O, Schmitt TM, Greenberg PD, Kranz DM. Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains. Journal of Immunology (Baltimore, Md. : 1950). PMID 29288199 DOI: 10.4049/Jimmunol.1700236 |
0.506 |
|
2017 |
Schmitt TM, Aggen DH, Ishida-Tsubota K, Ochsenreither S, Kranz DM, Greenberg PD. Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro. Nature Biotechnology. PMID 29106410 DOI: 10.1038/Nbt.4004 |
0.577 |
|
2017 |
Stromnes IM, Hulbert A, Pierce RH, Greenberg PD, Hingorani SR. T-cell Localization, Activation, and Clonal Expansion in Human Pancreatic Ductal Adenocarcinoma. Cancer Immunology Research. PMID 29066497 DOI: 10.1158/2326-6066.Cir-16-0322 |
0.817 |
|
2017 |
Oda SK, Daman AW, Garcia NM, Wagener F, Schmitt TM, Tan X, Chapuis AG, Greenberg PD. A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T cell function and therapy of murine leukemia. Blood. PMID 29042364 DOI: 10.1182/Blood-2017-04-777052 |
0.62 |
|
2017 |
Ban YH, Oh SC, Seo SH, Kim SM, Choi IP, Greenberg PD, Chang J, Kim TD, Ha SJ. miR-150-Mediated Foxo1 Regulation Programs CD8(+) T Cell Differentiation. Cell Reports. 20: 2598-2611. PMID 28903041 DOI: 10.1016/J.Celrep.2017.08.065 |
0.475 |
|
2017 |
Kim TD, Jung HR, Seo SH, Oh SC, Ban Y, Tan X, Min Kim J, Hyun Lee S, Koh DS, Jung H, Park YJ, Ran Yoon S, Doh J, Ha SJ, Choi I, ... Greenberg PD, et al. MicroRNA-150 modulates intracellular Ca (2+) levels in naïve CD8(+) T cells by targeting TMEM20. Scientific Reports. 7: 2623. PMID 28572627 DOI: 10.1038/S41598-017-02697-X |
0.443 |
|
2017 |
Chapuis AG, Desmarais C, Emerson R, Schmitt TM, Shibuya K, Lai I, Wagener F, Chou J, Roberts IM, Coffey DG, Warren E, Robbins H, Greenberg PD, Yee C. Tracking the Fate and Origin of Clinically Relevant Adoptively Transferred CD8(+) T Cells In Vivo. Science Immunology. 2. PMID 28367538 DOI: 10.1126/Sciimmunol.Aal2568 |
0.563 |
|
2017 |
Anderson KG, Stromnes IM, Greenberg PD. Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies. Cancer Cell. 31: 311-325. PMID 28292435 DOI: 10.1016/J.Ccell.2017.02.008 |
0.859 |
|
2017 |
Paulson KG, Perdicchio M, Kulikauskas R, Wagener F, Church C, Bui K, Vandeven N, Thomas H, McAfee M, Miller N, Chin KM, Su Z, Greenberg PD, Parvathaneni U, Bhatia S, et al. Augmentation of adoptive T-cell therapy for Merkel cell carcinoma with avelumab. Journal of Clinical Oncology. 35: 3044-3044. DOI: 10.1200/Jco.2017.35.15_Suppl.3044 |
0.837 |
|
2017 |
Greenberg PD, Chapuis A, Egan D, Stromnes I, Hingorani S, Oda S, Perret R, Anderson K, Schmitt T. Abstract IA18: Building better T cells for targeting and eliminating tumors Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-Ia18 |
0.812 |
|
2017 |
Anderson KG, Bates BM, Chiu EY, Greenberg PD. Abstract NTOC-078: ENGINEERING ADOPTIVE T CELL THERAPY FOR EFFICACY IN OVARIAN CANCER Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ntoc-078 |
0.593 |
|
2017 |
Anderson KG, Bates BM, Chiu EY, Greenberg PD. Abstract 4980: Engineering adoptive T cell therapy for efficacy in ovarian cancer Cancer Research. 77: 4980-4980. DOI: 10.1158/1538-7445.Am2017-4980 |
0.615 |
|
2016 |
Fallet B, Narr K, Ertuna YI, Remy M, Sommerstein R, Cornille K, Kreutzfeldt M, Page N, Zimmer G, Geier F, Straub T, Pircher H, Larimore K, Greenberg PD, Merkler D, et al. Interferon-driven deletion of antiviral B cells at the onset of chronic infection. Science Immunology. 1. PMID 27872905 DOI: 10.1126/Sciimmunol.Aah6817 |
0.466 |
|
2016 |
Sammicheli S, Kuka M, Di Lucia P, de Oya NJ, De Giovanni M, Fioravanti J, Cristofani C, Maganuco CG, Fallet B, Ganzer L, Sironi L, Mainetti M, Ostuni R, Larimore K, Greenberg PD, et al. Inflammatory monocytes hinder antiviral B cell responses. Science Immunology. 1. PMID 27868108 DOI: 10.1126/Sciimmunol.Aah6789 |
0.4 |
|
2016 |
Schietinger A, Philip M, Krisnawan VE, Chiu EY, Delrow JJ, Basom RS, Lauer P, Brockstedt DG, Knoblaugh SE, Hämmerling GJ, Schell TD, Garbi N, Greenberg PD. Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis. Immunity. PMID 27521269 DOI: 10.1016/J.Immuni.2016.07.011 |
0.619 |
|
2016 |
DeWitt WS, Lindau P, Snyder TM, Sherwood AM, Vignali M, Carlson CS, Greenberg PD, Duerkopp N, Emerson RO, Robins HS. A Public Database of Memory and Naive B-Cell Receptor Sequences. Plos One. 11: e0160853. PMID 27513338 DOI: 10.1371/Journal.Pone.0160853 |
0.337 |
|
2016 |
Stromnes IM, Greenberg PD. Pancreatic Cancer: Planning Ahead for Metastatic Spread. Cancer Cell. 29: 774-6. PMID 27300430 DOI: 10.1016/J.Ccell.2016.05.013 |
0.661 |
|
2016 |
Chapuis AG, Roberts IM, Thompson JA, Margolin KA, Bhatia S, Lee SM, Sloan HL, Lai IP, Farrar EA, Wagener F, Shibuya KC, Cao J, Wolchok JD, Greenberg PD, Yee C. T-Cell Therapy Using Interleukin-21-Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27269940 DOI: 10.1200/Jco.2015.65.5142 |
0.629 |
|
2016 |
Chapuis AG, Lee SM, Thompson JA, Roberts IM, Margolin KA, Bhatia S, Sloan HL, Lai I, Wagener F, Shibuya K, Cao J, Wolchok JD, Greenberg PD, Yee C. Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient. The Journal of Experimental Medicine. PMID 27242164 DOI: 10.1084/Jem.20152021 |
0.447 |
|
2016 |
Gartlan KH, Krashias G, Wegmann F, Hillson WR, Scherer EM, Greenberg PD, Eisenbarth SC, Moghaddam AE, Sattentau QJ. Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns. Vaccine. 34: 2188-96. PMID 27005810 DOI: 10.1016/J.Vaccine.2016.03.025 |
0.394 |
|
2016 |
Chapuis A, Egan DN, Bar M, Schmitt TM, McAfee M, Perdicchio M, Ragnarsson GB, Yeung CC, Nguyen H, Kropp L, Castelli L, Wagener F, Hunter D, Cohen K, Seese A, ... ... Greenberg PD, et al. EBV-Specific Donor Cells Transduced to Express a High-Affinity WT1 TCR Can Prevent Recurrence in Post-HCT Patients with High-Risk AML Blood. 128: 1001-1001. DOI: 10.1182/Blood.V128.22.1001.1001 |
0.814 |
|
2016 |
Stromnes IM, Schmitt TM, Brockenbrough SJ, Nguyen H, Cuevas C, Hulbert A, Hotes J, Dotson A, Hingorani SR, Greenberg PD. Abstract IA38: Engineered T cell-receptor based therapy of pancreatic ductal adenocarcinoma Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-Ia38 |
0.804 |
|
2016 |
Greenberg PD, Anderson KG, Egan D, Hingorani SR, Oda SK, Perret R, Schietinger A, Schmitt TM, Stromnes IM, Wilkens A, Chapuis AG. Abstract IA01: Engineering T cell responses to tumors: Taking the immune system where no responses have gone before Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-Ia01 |
0.825 |
|
2015 |
Stromnes IM, Schmitt TM, Hulbert A, Brockenbrough JS, Nguyen HN, Cuevas C, Dotson AM, Tan X, Hotes JL, Greenberg PD, Hingorani SR. T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma. Cancer Cell. 28: 638-52. PMID 26525103 DOI: 10.1016/J.Ccell.2015.09.022 |
0.804 |
|
2015 |
Schmitt TM, Stromnes IM, Chapuis AG, Greenberg PD. New Strategies in Engineering T-cell Receptor Gene-Modified T Cells to More Effectively Target Malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26463711 DOI: 10.1158/1078-0432.Ccr-15-0860 |
0.812 |
|
2015 |
Chowell D, Krishna S, Becker PD, Cocita C, Shu J, Tan X, Greenberg PD, Klavinskis LS, Blattman JN, Anderson KS. TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes. Proceedings of the National Academy of Sciences of the United States of America. 112: E1754-62. PMID 25831525 DOI: 10.1073/Pnas.1500973112 |
0.733 |
|
2015 |
Stromnes IM, Brockenbrough SJ, Schmitt TM, Hingorani SR, Greenberg PD. Abstract PR08: Enhanced affinity T cell receptor based therapy can surmount immune and physical barriers to treat pancreatic ductal adenocarcinoma Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-Pr08 |
0.808 |
|
2015 |
Stromnes IM, Brockenbrough S, Schmitt TM, Hotes JD, Carlson MA, Cuevos C, Greenberg PD, Hingorani SR. Abstract PR10: Re-engineering immunity to treat pancreas cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Pr10 |
0.803 |
|
2015 |
Greenberg PD, Schmitt TM, Schietinger A, Stromnes IM, Hingorani SR, Oda SK, Perret R, Anderson KG, Bar M, Chapuis AG. Abstract SY31-03: Employing TCRs in engineered T cells to develop therapeutic reagents for effectively targeting malignancies Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy31-03 |
0.827 |
|
2014 |
Corrigan-Curay J, Kiem HP, Baltimore D, O'Reilly M, Brentjens RJ, Cooper L, Forman S, Gottschalk S, Greenberg P, Junghans R, Heslop H, Jensen M, Mackall C, June C, Press O, et al. T-cell immunotherapy: looking forward. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1564-74. PMID 25186558 DOI: 10.1038/Mt.2014.148 |
0.63 |
|
2014 |
Stromnes IM, Greenberg PD, Hingorani SR. Molecular pathways: myeloid complicity in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5157-70. PMID 25047706 DOI: 10.1158/1078-0432.Ccr-13-0866 |
0.744 |
|
2014 |
Stromnes IM, DelGiorno KE, Greenberg PD, Hingorani SR. Stromal reengineering to treat pancreas cancer. Carcinogenesis. 35: 1451-60. PMID 24908682 DOI: 10.1093/Carcin/Bgu115 |
0.71 |
|
2014 |
Kim N, Kim M, Yun S, Doh J, Greenberg PD, Kim TD, Choi I. MicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1. The Journal of Allergy and Clinical Immunology. 134: 195-203. PMID 24698324 DOI: 10.1016/J.Jaci.2014.02.018 |
0.391 |
|
2014 |
Wölfl M, Greenberg PD. Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells. Nature Protocols. 9: 950-66. PMID 24675735 DOI: 10.1038/Nprot.2014.064 |
0.587 |
|
2014 |
Stromnes IM, Brockenbrough JS, Izeradjene K, Carlson MA, Cuevas C, Simmons RM, Greenberg PD, Hingorani SR. Targeted depletion of an MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity Gut. 63: 1769-1781. PMID 24555999 DOI: 10.1136/Gutjnl-2013-306271 |
0.761 |
|
2014 |
Stromnes IM, Schmitt TM, Chapuis AG, Hingorani SR, Greenberg PD. Re-adapting T cells for cancer therapy: from mouse models to clinical trials. Immunological Reviews. 257: 145-64. PMID 24329795 DOI: 10.1111/Imr.12141 |
0.802 |
|
2014 |
Schietinger A, Greenberg PD. Tolerance and exhaustion: defining mechanisms of T cell dysfunction. Trends in Immunology. 35: 51-60. PMID 24210163 DOI: 10.1016/J.It.2013.10.001 |
0.624 |
|
2014 |
Bot A, Chiriva-Internati M, Cornforth A, Czerniecki BJ, Ferrone S, Geles K, Greenberg PD, Hurt E, Koya RC, Manjili MH, Matsui W, Morgan RA, Palena CM, Powell Jr DJ, Restifo NP, et al. Stem cells and cancer immunotherapy: Arrowhead’s 2nd annual cancer immunotherapy conference Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-6 |
0.328 |
|
2014 |
Bar M, Chapuis AG, Schmitt TM, Nguyen H, Duerkopp NA, Tom MF, Wagener FD, Chaney CN, Bui K, Heimfeld S, Greenberg PD. Transferred Donor-Derived Virus Specific CD8+ T Cells That Have Been Transduced to Express a WT1-Specific T Cell Receptor Can Persist and Provide Anti-Leukemic Activity in AML Patients Post-Transplant Blood. 124: 3939-3939. DOI: 10.1182/Blood.V124.21.3939.3939 |
0.543 |
|
2013 |
Schmitt TM, Aggen DH, Stromnes IM, Dossett ML, Richman SA, Kranz DM, Greenberg PD. Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. Blood. 122: 348-56. PMID 23673862 DOI: 10.1182/Blood-2013-01-478164 |
0.869 |
|
2013 |
Demidenko AA, Blattman JN, Blattman NN, Greenberg PD, Nibert ML. Engineering recombinant reoviruses with tandem repeats and a tetravirus 2A-like element for exogenous polypeptide expression. Proceedings of the National Academy of Sciences of the United States of America. 110: E1867-76. PMID 23630248 DOI: 10.1073/Pnas.1220107110 |
0.662 |
|
2013 |
Chapuis AG, Ragnarsson GB, Nguyen HN, Chaney CN, Pufnock JS, Schmitt TM, Duerkopp N, Roberts IM, Pogosov GL, Ho WY, Ochsenreither S, Wölfl M, Bar M, Radich JP, Yee C, ... Greenberg PD, et al. Transferred WT1-reactive CD8+ T cells can mediate antileukemic activity and persist in post-transplant patients. Science Translational Medicine. 5: 174ra27. PMID 23447018 DOI: 10.1126/Scitranslmed.3004916 |
0.578 |
|
2013 |
Berrien-Elliott MM, Jackson SR, Meyer JM, Rouskey CJ, Nguyen TL, Yagita H, Greenberg PD, DiPaolo RJ, Teague RM. Durable adoptive immunotherapy for leukemia produced by manipulation of multiple regulatory pathways of CD8+ T-cell tolerance. Cancer Research. 73: 605-16. PMID 23188506 DOI: 10.1158/0008-5472.Can-12-2179 |
0.641 |
|
2013 |
Stroncek DF, Melief CJ, Castiello L, Cesano A, Cheever MA, Civini S, Comin-Anduix B, Gajewski TF, Greenberg PD, Kalinski P, Kaufman HL, Kershaw MH, Khleif SN, Marincola F, Merritt W, et al. Highlights of the society for immunotherapy of cancer (SITC) 27th annual meeting Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-4 |
0.406 |
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2013 |
Schmitt TM, Greenberg PD, Aggen DH, Kranz D, Ochsenreither S. Abstract PR12: Early TCRα expression during T cell development for the generation of enhanced-affinity TCRs for TCR gene therapy. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-Pr12 |
0.494 |
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2013 |
Chapuis AG, Thompson JA, Margolin KA, Byrd D, Bhatia S, Lee SM, Lai IP, Roberts IM, Sloan HL, Greenberg PD, Yee C. Abstract PR11: Enhanced in vivo persistence and therapeutic activity of combined transferred polyclonal melanoma-reactive CTL generated in presence of IL-21 and anti-CTLA4. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-Pr11 |
0.538 |
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2013 |
Greenberg PD, Ochsenreither S, Schmitt T, Aggen D, Kranz D, Wolfl M, Kuball J, Majeti R, Weissman I, Stromnes I, Schietinger A, Ragnarsson G, Yee C, Bar M, Chapuis A. Abstract IA1: T cells vs. tumor cells: Arming/deploying T cells for a successful battle. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-Ia1 |
0.83 |
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2012 |
Chou CK, Schietinger A, Liggitt HD, Tan X, Funk S, Freeman GJ, Ratliff TL, Greenberg NM, Greenberg PD. Cell-intrinsic abrogation of TGF-β signaling delays but does not prevent dysfunction of self/tumor-specific CD8 T cells in a murine model of autochthonous prostate cancer. Journal of Immunology (Baltimore, Md. : 1950). 189: 3936-46. PMID 22984076 DOI: 10.4049/Jimmunol.1201415 |
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2012 |
Wegmann F, Gartlan KH, Harandi AM, Brinckmann SA, Coccia M, Hillson WR, Kok WL, Cole S, Ho LP, Lambe T, Puthia M, Svanborg C, Scherer EM, Krashias G, Williams A, ... ... Greenberg PD, et al. Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens. Nature Biotechnology. 30: 883-8. PMID 22922673 DOI: 10.1038/Nbt.2344 |
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2012 |
Larimore K, McCormick MW, Robins HS, Greenberg PD. Shaping of human germline IgH repertoires revealed by deep sequencing. Journal of Immunology (Baltimore, Md. : 1950). 189: 3221-30. PMID 22865917 DOI: 10.4049/Jimmunol.1201303 |
0.305 |
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2012 |
Stromnes IM, Fowler C, Casamina CC, Georgopolos CM, McAfee MS, Schmitt TM, Tan X, Kim TD, Choi I, Blattman JN, Greenberg PD. Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 189: 1812-25. PMID 22798667 DOI: 10.4049/Jimmunol.1200552 |
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2012 |
Ochsenreither S, Majeti R, Schmitt T, Stirewalt D, Keilholz U, Loeb KR, Wood B, Choi YE, Bleakley M, Warren EH, Hudecek M, Akatsuka Y, Weissman IL, Greenberg PD. Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen. Blood. 119: 5492-501. PMID 22529286 DOI: 10.1182/Blood-2011-07-365890 |
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2012 |
Provasi E, Genovese P, Lombardo A, Magnani Z, Liu PQ, Reik A, Chu V, Paschon DE, Zhang L, Kuball J, Camisa B, Bondanza A, Casorati G, Ponzoni M, Ciceri F, ... ... Greenberg PD, et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nature Medicine. 18: 807-15. PMID 22466705 DOI: 10.1038/Nm.2700 |
0.594 |
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2012 |
Till BG, Jensen MC, Wang J, Qian X, Gopal AK, Maloney DG, Lindgren CG, Lin Y, Pagel JM, Budde LE, Raubitschek A, Forman SJ, Greenberg PD, Riddell SR, Press OW. CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood. 119: 3940-50. PMID 22308288 DOI: 10.1182/Blood-2011-10-387969 |
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2012 |
Schietinger A, Delrow JJ, Basom RS, Blattman JN, Greenberg PD. Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state. Science (New York, N.Y.). 335: 723-7. PMID 22267581 DOI: 10.1126/Science.1214277 |
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2012 |
Aggen DH, Chervin AS, Schmitt TM, Engels B, Stone JD, Richman SA, Piepenbrink KH, Baker BM, Greenberg PD, Schreiber H, Kranz DM. Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains. Gene Therapy. 19: 365-74. PMID 21753797 DOI: 10.1038/Gt.2011.104 |
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2012 |
Ochsenreither S, Majeti R, Loeb K, Stirewalt DL, Keilholz U, Weissman IL, Greenberg PD. Cyclin-A1 expression in acute myeloid leukemia stem cells and its representation as an immunogenic antigen that can be targeted by cytotoxic T cells. Journal of Clinical Oncology. 30: 2523-2523. DOI: 10.1200/Jco.2012.30.15_Suppl.2523 |
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2012 |
Finton K, Larmen B, Larimore K, Stuart A, Friend D, Vanden Bos T, Greenberg P, Elledge S, Stamatatos L, Strong R. Functional properties of an ensemble of candidate germline-encoded precursors of the anti-MPER antibody 4E10 Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P344 |
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2012 |
Chapuis AG, Ragnarsson GB, Nguyen H, Chaney CN, Pufnock J, Schmitt T, Duerkopp N, Roberts I, Pogosov G, Ho W, Bar M, Radich JP, Yee C, Greenberg P. Transferred Donor-Derived WT1-Specific CD8+ T-Cell Clones After Hematopoietic Cell Transplantation Mediate Antileukemic Activity and Can Establish Persistent Responses without Toxicity to Normal Tissues in High-Risk Leukemia Patients Blood. 120: 350-350. DOI: 10.1182/Blood.V120.21.350.350 |
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2012 |
Chapuis AG, Thompson JA, Margolin KA, Byrd D, Bhatia S, Lee SM, Roberts I, Lai I, Farrar E, Greenberg PD, Yee C. Abstract LB-136: IL-21-derived melanoma-reactive CTL combined with anti-CTLA4 persist, acquire central memory characteristics, and mediate tumor regression in patients with metastatic melanoma Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-136 |
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2011 |
Greenberg PD. Ralph M. Steinman: a man, a microscope, a cell, and so much more. Proceedings of the National Academy of Sciences of the United States of America. 108: 20871-2. PMID 22158987 DOI: 10.1073/Pnas.1119293109 |
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2011 |
Kim TD, Lee SU, Yun S, Sun HN, Lee SH, Kim JW, Kim HM, Park SK, Lee CW, Yoon SR, Greenberg PD, Choi I. Human microRNA-27a* targets Prf1 and GzmB expression to regulate NK-cell cytotoxicity. Blood. 118: 5476-86. PMID 21960590 DOI: 10.1182/Blood-2011-04-347526 |
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2011 |
Tan X, Sande JL, Pufnock JS, Blattman JN, Greenberg PD. Retinoic acid as a vaccine adjuvant enhances CD8+ T cell response and mucosal protection from viral challenge. Journal of Virology. 85: 8316-27. PMID 21653670 DOI: 10.1128/Jvi.00781-11 |
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2011 |
Pufnock JS, Cigal M, Rolczynski LS, Andersen-Nissen E, Wolfl M, McElrath MJ, Greenberg PD. Priming CD8+ T cells with dendritic cells matured using TLR4 and TLR7/8 ligands together enhances generation of CD8+ T cells retaining CD28. Blood. 117: 6542-51. PMID 21493800 DOI: 10.1182/Blood-2010-11-317966 |
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Stone JD, Aggen DH, Chervin AS, Narayanan S, Schmitt TM, Greenberg PD, Kranz DM. Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8. Journal of Immunology (Baltimore, Md. : 1950). 186: 5193-200. PMID 21451107 DOI: 10.4049/Jimmunol.1003755 |
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Chapuis AG, Casper C, Kuntz S, Zhu J, Tjernlund A, Diem K, Turtle CJ, Cigal ML, Velez R, Riddell S, Corey L, Greenberg PD. HIV-specific CD8+ T cells from HIV+ individuals receiving HAART can be expanded ex vivo to augment systemic and mucosal immunity in vivo. Blood. 117: 5391-402. PMID 21422474 DOI: 10.1182/Blood-2010-11-320226 |
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Wölfl M, Merker K, Morbach H, Van Gool SW, Eyrich M, Greenberg PD, Schlegel PG. Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy. Cancer Immunology, Immunotherapy : Cii. 60: 173-86. PMID 20972785 DOI: 10.1007/S00262-010-0928-8 |
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Kuball J, de Boer K, Wagner E, Wattad M, Antunes E, Weeratna RD, Vicari AP, Lotz C, van Dorp S, Hol S, Greenberg PD, Heit W, Davis HL, Theobald M. Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909. Cancer Immunology, Immunotherapy : Cii. 60: 161-71. PMID 20963411 DOI: 10.1007/S00262-010-0929-7 |
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2011 |
Rhee EG, Blattman JN, Kasturi SP, Kelley RP, Kaufman DR, Lynch DM, La Porte A, Simmons NL, Clark SL, Pulendran B, Greenberg PD, Barouch DH. Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors. Journal of Virology. 85: 315-23. PMID 20962088 DOI: 10.1128/Jvi.01597-10 |
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Provasi E, Genovese P, Lombardo A, Magnani Z, Liu P, Reik A, Chu V, Paschon DE, Zhang L, Kuball J, Camisa B, Bondanza A, Casorati G, Ponzoni M, Ciceri F, ... ... Greenberg PD, et al. TCR Gene Editing Results in Effective Immunotherapy of Leukemia without the Development of GvHD Blood. 118: 667-667. DOI: 10.1182/Blood.V118.21.667.667 |
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Stromnes IM, Blattman JN, Tan X, Jeevanjee S, Gu H, Greenberg PD. Abrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice. The Journal of Clinical Investigation. 120: 3722-34. PMID 20890046 DOI: 10.1172/Jci41991 |
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Fowler CC, Pao LI, Blattman JN, Greenberg PD. SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 3256-67. PMID 20696858 DOI: 10.4049/Jimmunol.1001362 |
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Lee SH, Yun S, Piao ZH, Jeong M, Kim DO, Jung H, Lee J, Kim MJ, Kim MS, Chung JW, Kim TD, Yoon SR, Greenberg PD, Choi I. Suppressor of cytokine signaling 2 regulates IL-15-primed human NK cell function via control of phosphorylated Pyk2. Journal of Immunology (Baltimore, Md. : 1950). 185: 917-28. PMID 20543098 DOI: 10.4049/Jimmunol.1000784 |
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James SE, Greenberg PD, Jensen MC, Lin Y, Wang J, Budde LE, Till BG, Raubitschek AA, Forman SJ, Press OW. Mathematical modeling of chimeric TCR triggering predicts the magnitude of target lysis and its impairment by TCR downmodulation. Journal of Immunology (Baltimore, Md. : 1950). 184: 4284-94. PMID 20220093 DOI: 10.4049/Jimmunol.0903701 |
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2010 |
Till BG, Jensen MC, Qian X, Wang J, Gopal AK, Maloney DG, Lindgren CG, Lin Y, Pagel JM, Budde LE, Raubitschek A, Forman S, Greenberg P, Riddell SR, Press OW. Phase I Trial Results Testing Adoptively Transferred T Cells Expressing CD20-Specific Chimeric Antigen Receptors Containing CD28 and CD137 Costimulatory Domains In Patients with Mantle Cell Lymphoma and Indolent Lymphoma Blood. 116: 561-561. DOI: 10.1182/Blood.V116.21.561.561 |
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2010 |
Provasi E, Genovese P, Lombardo A, Magnani Z, Reik A, Liu P, Chu V, Kuball J, Bondanza A, Casorati G, Ciceri F, Bordignon C, Greenberg PD, Holmes MC, Gregory PD, et al. Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia. Blood. 116: 3764-3764. DOI: 10.1182/Blood.V116.21.3764.3764 |
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Genovese P, Provasi E, Magnani Z, Lombardo A, Pello OM, Kuball J, Bondanza A, Gregory PD, Bordignon C, Holmes MC, Greenberg PD, Naldini L, Bonini C. Abstract 2937: Editing central memory T lymphocyte specificity for safe and effective adoptive immunotherapy of leukemia Cancer Research. 70: 2937-2937. DOI: 10.1158/1538-7445.Am10-2937 |
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Lee SH, Yun S, Lee J, Kim MJ, Piao ZH, Jeong M, Chung JW, Kim TD, Yoon SR, Greenberg PD, Choi I. RasGRP1 is required for human NK cell function. Journal of Immunology (Baltimore, Md. : 1950). 183: 7931-8. PMID 19933860 DOI: 10.4049/Jimmunol.0902012 |
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James SE, Orgun NN, Tedder TF, Shlomchik MJ, Jensen MC, Lin Y, Greenberg PD, Press OW. Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice. Blood. 114: 5454-63. PMID 19880489 DOI: 10.1182/Blood-2009-08-232967 |
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Schmitt TM, Ragnarsson GB, Greenberg PD. T cell receptor gene therapy for cancer. Human Gene Therapy. 20: 1240-8. PMID 19702439 DOI: 10.1089/Hum.2009.146 |
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Dossett ML, Teague RM, Schmitt TM, Tan X, Cooper LJ, Pinzon C, Greenberg PD. Adoptive immunotherapy of disseminated leukemia with TCR-transduced, CD8+ T cells expressing a known endogenous TCR. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 742-9. PMID 19209146 DOI: 10.1038/Mt.2008.300 |
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Kuball J, Hauptrock B, Malina V, Antunes E, Voss RH, Wolfl M, Strong R, Theobald M, Greenberg PD. Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain. The Journal of Experimental Medicine. 206: 463-75. PMID 19171765 DOI: 10.1084/Jem.20082487 |
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Richman SA, Aggen DH, Dossett ML, Donermeyer DL, Allen PM, Greenberg PD, Kranz DM. Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments. Molecular Immunology. 46: 902-16. PMID 18962897 DOI: 10.1016/J.Molimm.2008.09.021 |
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Blattman J, Tan X, Sande J, Pufnock J, Greenberg P. P02-05. All-trans retinoic acid during vaccination increases Ag-specific CD8 T cell homing to mucosal sites and improves recall responses to vaginal challenge Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P10 |
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Provasi E, Genovese P, Magnani Z, Pello OM, Kuball J, Lombardo A, Bondanza A, Gregory PD, Bordignon C, Holmes MC, Greenberg PD, Naldini L, Bonini C. From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia. Blood. 114: 374-374. DOI: 10.1182/Blood.V114.22.374.374 |
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Wölfl M, Rutebemberwa A, Mosbruger T, Mao Q, Li HM, Netski D, Ray SC, Pardoll D, Sidney J, Sette A, Allen T, Kuntzen T, Kavanagh DG, Kuball J, Greenberg PD, et al. Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire. Journal of Immunology (Baltimore, Md. : 1950). 181: 6435-46. PMID 18941234 DOI: 10.4049/Jimmunol.181.9.6435 |
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Rice J, Dossett ML, Ohlén C, Buchan SL, Kendall TJ, Dunn SN, Stevenson FK, Greenberg PD. DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire. European Journal of Immunology. 38: 2118-30. PMID 18624299 DOI: 10.1002/Eji.200838213 |
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Wölfl M, Kuball J, Eyrich M, Schlegel PG, Greenberg PD. Use of CD137 to study the full repertoire of CD8+ T cells without the need to know epitope specificities. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 1043-9. PMID 18561198 DOI: 10.1002/Cyto.A.20594 |
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Till BG, Jensen MC, Wang J, Chen EY, Wood BL, Greisman HA, Qian X, James SE, Raubitschek A, Forman SJ, Gopal AK, Pagel JM, Lindgren CG, Greenberg PD, Riddell SR, et al. Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells. Blood. 112: 2261-71. PMID 18509084 DOI: 10.1182/Blood-2007-12-128843 |
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James SE, Greenberg PD, Jensen MC, Lin Y, Wang J, Till BG, Raubitschek AA, Forman SJ, Press OW. Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane Journal of Immunology. 180: 7028-7038. PMID 18453625 DOI: 10.4049/Jimmunol.180.10.7028 |
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Teague RM, Greenberg PD, Fowler C, Huang MZ, Tan X, Morimoto J, Dossett ML, Huseby ES, Ohlén C. Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor. Immunity. 28: 662-74. PMID 18424189 DOI: 10.1016/J.Immuni.2008.03.012 |
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Wang J, Jensen M, Lin Y, Sui X, Chen E, Lindgren CG, Till B, Raubitschek A, Forman SJ, Qian X, James S, Greenberg P, Riddell S, Press OW. Optimizing adoptive polyclonal T cell immunotherapy of lymphomas, using a chimeric T cell receptor possessing CD28 and CD137 costimulatory domains. Human Gene Therapy. 18: 712-25. PMID 17685852 DOI: 10.1089/Hum.2007.028 |
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Morimoto J, Tan X, Teague RM, Ohlén C, Greenberg PD. Induction of tolerance in CD8+ T cells to a transgenic autoantigen expressed in the liver does not require cross-presentation. Journal of Immunology (Baltimore, Md. : 1950). 178: 6849-60. PMID 17513733 DOI: 10.4049/Jimmunol.178.11.6849 |
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Wolfl M, Kuball J, Ho WY, Nguyen H, Manley TJ, Bleakley M, Greenberg PD. Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities. Blood. 110: 201-10. PMID 17371945 DOI: 10.1182/Blood-2006-11-056168 |
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Kraft AR, Krux F, Schimmer S, Ohlen C, Greenberg PD, Dittmer U. CpG oligodeoxynucleotides allow for effective adoptive T-cell therapy in chronic retroviral infection. Blood. 109: 2982-4. PMID 17148590 DOI: 10.1182/Blood-2006-06-022178 |
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Kuball J, Dossett ML, Wolfl M, Ho WY, Voss RH, Fowler C, Greenberg PD. Facilitating matched pairing and expression of TCR chains introduced into human T cells. Blood. 109: 2331-8. PMID 17082316 DOI: 10.1182/Blood-2006-05-023069 |
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Till BG, Jensen MC, Wang J, Chen EY, James S, Raubitschek A, Forman SJ, Gopal AK, Pagel JM, Lindgren CG, Greenberg PD, Riddell SR, Press OW. Adoptive Cellular Therapy for Follicular Lymphoma Using Genetically-Modified Autologous CD20-Specific T Cells. Blood. 110: 499-499. DOI: 10.1182/Blood.V110.11.499.499 |
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Cheng L, Greenberg P. Delivery Of Augmented Il-2 Receptor Signals To Cd8+ T Cells Replaces The Requirement For Helper Function In The Generation Of Primary But Not Secondary Cd8+ T Cell Responses Journal of Allergy and Clinical Immunology. 119: S92. DOI: 10.1016/J.Jaci.2006.11.386 |
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Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proceedings of the National Academy of Sciences of the United States of America. 103: 6659-64. PMID 16617117 DOI: 10.1073/Pnas.0509484103 |
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Richman SA, Healan SJ, Weber KS, Donermeyer DL, Dossett ML, Greenberg PD, Allen PM, Kranz DM. Development of a novel strategy for engineering high-affinity proteins by yeast display. Protein Engineering, Design & Selection : Peds. 19: 255-64. PMID 16549400 DOI: 10.1093/Protein/Gzl008 |
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Blattman JN, Greenberg PD. PD-1 blockade: rescue from a near-death experience. Nature Immunology. 7: 227-8. PMID 16482167 DOI: 10.1038/Ni0306-227 |
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Teague RM, Sather BD, Sacks JA, Huang MZ, Dossett ML, Morimoto J, Tan X, Sutton SE, Cooke MP, Ohlén C, Greenberg PD. Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors. Nature Medicine. 12: 335-41. PMID 16474399 DOI: 10.1038/Nm1359 |
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Ho WY, Nguyen HN, Wolfl M, Kuball J, Greenberg PD. In vitro methods for generating CD8+ T-cell clones for immunotherapy from the naïve repertoire. Journal of Immunological Methods. 310: 40-52. PMID 16469329 DOI: 10.1016/J.Jim.2005.11.023 |
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Press OW, Wang J, Lindgren CG, Chen EY, Gopal AK, Pagel JM, Qian X, Riddell SR, Greenberg PD, Raubitschek A, Jensen MC. 53. Preliminary Results of a Pilot Phase I Clinical Trial of Adoptive Immunotherapy for B Cell Lymphoma Using CD8+ T Cells Genetically Modified To Express a Chimeric T Cell Receptor Recognizing CD20 Molecular Therapy. 13: S22-S23. DOI: 10.1016/J.Ymthe.2006.08.068 |
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Muraro S, Bondanza A, Bellone M, Greenberg PD, Bonini C. Molecular modification of idiotypes from B-cell lymphomas for expression in mature dendritic cells as a strategy to induce tumor-reactive CD4+ and CD8+ T-cell responses. Blood. 105: 3596-604. PMID 15650058 DOI: 10.1182/Blood-2004-07-2890 |
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Ochsenbein AF, Riddell SR, Brown M, Corey L, Baerlocher GM, Lansdorp PM, Greenberg PD. CD27 expression promotes long-term survival of functional effector-memory CD8+ cytotoxic T lymphocytes in HIV-infected patients. The Journal of Experimental Medicine. 200: 1407-17. PMID 15583014 DOI: 10.1084/Jem.20040717 |
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Zhang Y, Blattman JN, Kennedy NJ, Duong J, Nguyen T, Wang Y, Davis RJ, Greenberg PD, Flavell RA, Dong C. Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Nature. 430: 793-7. PMID 15306813 DOI: 10.1038/Nature02764 |
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Blattman JN, Greenberg PD. Cancer immunotherapy: a treatment for the masses. Science (New York, N.Y.). 305: 200-5. PMID 15247469 DOI: 10.1126/Science.1100369 |
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Cooper LJ, Topp MS, Pinzon C, Plavec I, Jensen MC, Riddell SR, Greenberg PD. Enhanced transgene expression in quiescent and activated human CD8+ T cells. Human Gene Therapy. 15: 648-58. PMID 15242525 DOI: 10.1089/1043034041361217 |
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Mossman SP, Pierce CC, Watson AJ, Robertson MN, Montefiori DC, Kuller L, Richardson BA, Bradshaw JD, Munn RJ, Hu SL, Greenberg PD, Benveniste RE, Haigwood NL. Protective immunity to SIV challenge elicited by vaccination of macaques with multigenic DNA vaccines producing virus-like particles. Aids Research and Human Retroviruses. 20: 425-34. PMID 15157361 DOI: 10.1089/088922204323048177 |
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Liao X, Li Y, Bonini C, Nair S, Gilboa E, Greenberg PD, Yee C. Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 757-64. PMID 15120337 DOI: 10.1016/J.Ymthe.2004.02.011 |
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Wang J, Press OW, Lindgren CG, Greenberg P, Riddell S, Qian X, Laugen C, Raubitschek A, Forman SJ, Jensen MC. Cellular immunotherapy for follicular lymphoma using genetically modified CD20-specific CD8+ cytotoxic T lymphocytes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 577-86. PMID 15093188 DOI: 10.1016/J.Ymthe.2003.12.011 |
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Dittmer U, He H, Messer RJ, Schimmer S, Olbrich AR, Ohlen C, Greenberg PD, Stromnes IM, Iwashiro M, Sakaguchi S, Evans LH, Peterson KE, Yang G, Hasenkrug KJ. Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection. Immunity. 20: 293-303. PMID 15030773 DOI: 10.1016/S1074-7613(04)00054-8 |
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Shur A, Hsing L, Yang Y, Dossett M, Ohlen C, Riddell S, Greenberg P. 396 Cd8+ T Cells As Immunogenic Vaccine Vehicles. Journal of Investigative Medicine. 52. DOI: 10.1136/Jim-52-Suppl1-396 |
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Doria-Rose NA, Ohlen C, Polacino P, Pierce CC, Hensel MT, Kuller L, Mulvania T, Anderson D, Greenberg PD, Hu S, Haigwood NL. Multigene DNA Priming-Boosting Vaccines Protect Macaques from Acute CD4+-T-Cell Depletion after Simian-Human Immunodeficiency Virus SHIV89.6P Mucosal Challenge Journal of Virology. 78: 13396-13396. DOI: 10.1128/Jvi.78.23.13396.2004 |
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2004 |
Shur A, Hsing L, Yang Y, Dossett M, Ohlen C, Riddell S, Greenberg P. CD8+ T CELLS AS IMMUNOGENIC VACCINE VEHICLES. Journal of Investigative Medicine. 52: S91. DOI: 10.1097/00042871-200401001-00074 |
0.764 |
|
2004 |
Muraro S, Bondanza A, Bellone M, Greenberg P, Bonini C. 350. Gene Transfer of Modified Idiotype into Dendritic Cells for Immunotherapy of Non-Hodgkin Lymphomas Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.301 |
0.508 |
|
2003 |
Doria-Rose NA, Ohlen C, Polacino P, Pierce CC, Hensel MT, Kuller L, Mulvania T, Anderson D, Greenberg PD, Hu SL, Haigwood NL. Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge. Journal of Virology. 77: 11563-77. PMID 14557642 DOI: 10.1128/Jvi.77.21.11563-11577.2003 |
0.335 |
|
2003 |
Topp MS, Riddell SR, Akatsuka Y, Jensen MC, Blattman JN, Greenberg PD. Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production. The Journal of Experimental Medicine. 198: 947-55. PMID 12963692 DOI: 10.1084/Jem.20021288 |
0.759 |
|
2003 |
Ho WY, Blattman JN, Dossett ML, Yee C, Greenberg PD. Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction. Cancer Cell. 3: 431-7. PMID 12781360 DOI: 10.1016/S1535-6108(03)00113-2 |
0.856 |
|
2003 |
Seiffert M, Custodio JM, Wolf I, Harkey M, Liu Y, Blattman JN, Greenberg PD, Rohrschneider LR. Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent. Molecular and Cellular Biology. 23: 2415-24. PMID 12640125 DOI: 10.1128/Mcb.23.7.2415-2424.2003 |
0.682 |
|
2002 |
Warren EH, Tykodi SS, Murata M, Sandmaier BM, Storb R, Jaffee E, Childs R, Thompson JA, Greenberg PD, Riddell SR. T-cell therapy targeting minor histocompatibility Ags for the treatment of leukemia and renal-cell carcinoma. Cytotherapy. 4: 441. PMID 12473218 DOI: 10.1080/146532402320776116 |
0.562 |
|
2002 |
Ho WY, Yee C, Greenberg PD. Adoptive therapy with CD8(+) T cells: it may get by with a little help from its friends. The Journal of Clinical Investigation. 110: 1415-7. PMID 12438439 DOI: 10.1172/Jci17214 |
0.641 |
|
2002 |
Yee C, Thompson JA, Byrd D, Riddell SR, Roche P, Celis E, Greenberg PD. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 16168-73. PMID 12427970 DOI: 10.1073/Pnas.242600099 |
0.65 |
|
2002 |
Cheng LE, Greenberg PD. Selective delivery of augmented IL-2 receptor signals to responding CD8+ T cells increases the size of the acute antiviral response and of the resulting memory T cell pool. Journal of Immunology (Baltimore, Md. : 1950). 169: 4990-7. PMID 12391213 DOI: 10.4049/Jimmunol.169.9.4990 |
0.802 |
|
2002 |
Yee C, Greenberg P. Modulating T-cell immunity to tumours: New strategies for monitoring T-cell responses Nature Reviews Cancer. 2: 409-419. PMID 12189383 DOI: 10.1038/Nrc820 |
0.498 |
|
2002 |
Blattman JN, Cheng LE, Greenberg PD. CD8(+) T cell responses: it's all downhill after their prime. Nature Immunology. 3: 601-2. PMID 12087413 DOI: 10.1038/Ni0702-601 |
0.851 |
|
2002 |
Ohlén C, Kalos M, Cheng LE, Shur AC, Hong DJ, Carson BD, Kokot NC, Lerner CG, Sather BD, Huseby ES, Greenberg PD. CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function. The Journal of Experimental Medicine. 195: 1407-18. PMID 12045239 DOI: 10.1084/Jem.20011063 |
0.843 |
|
2002 |
Lewinsohn DA, Lines R, Lewinsohn DM, Riddell SR, Greenberg PD, Emerman M, Bartz SR. HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells. Virology. 294: 13-21. PMID 11886261 DOI: 10.1006/Viro.2001.1294 |
0.306 |
|
2002 |
Cheng LE, Ohlén C, Nelson BH, Greenberg PD. Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death. Proceedings of the National Academy of Sciences of the United States of America. 99: 3001-6. PMID 11867736 DOI: 10.1073/Pnas.052676899 |
0.793 |
|
2002 |
Ho WY, Yee C, Greenberg PD. Adoptive therapy with CD8 + T cells Journal of Clinical Investigation. 110: 1415-1417. DOI: 10.1172/Jci200217214 |
0.544 |
|
2001 |
Lisziewicz J, Gabrilovich DI, Varga G, Xu J, Greenberg PD, Arya SK, Bosch M, Behr JP, Lori F. Induction of potent human immunodeficiency virus type 1-specific T-cell-restricted immunity by genetically modified dendritic cells. Journal of Virology. 75: 7621-8. PMID 11462034 DOI: 10.1128/Jvi.75.16.7621-7628.2001 |
0.499 |
|
2001 |
Finch RJ, Fields PE, Greenberg PD. A transcriptional block in the IL-2 promoter at the -150 AP-1 site in effector CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 6530-6. PMID 11359804 DOI: 10.4049/Jimmunol.166.11.6530 |
0.827 |
|
2001 |
Bonini C, Lee SP, Riddell SR, Greenberg PD. Targeting antigen in mature dendritic cells for simultaneous stimulation of CD4+ and CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 5250-7. PMID 11290810 DOI: 10.4049/Jimmunol.166.8.5250 |
0.443 |
|
2001 |
Yee C, Riddell SR, Greenberg PD. In vivo tracking of tumor-specific T cells Current Opinion in Immunology. 13: 141-146. PMID 11228405 DOI: 10.1016/S0952-7915(00)00196-5 |
0.563 |
|
2001 |
Ohlén C, Kalos M, Hong DJ, Shur AC, Greenberg PD. Expression of a tolerizing tumor antigen in peripheral tissue does not preclude recovery of high-affinity CD8+ T cells or CTL immunotherapy of tumors expressing the antigen. Journal of Immunology (Baltimore, Md. : 1950). 166: 2863-70. PMID 11160355 DOI: 10.4049/Jimmunol.166.4.2863 |
0.619 |
|
2001 |
Berger C, Huang ML, Gough M, Greenberg PD, Riddell SR, Kiem HP. Nonmyeloablative immunosuppressive regimen prolongs In vivo persistence of gene-modified autologous T cells in a nonhuman primate model. Journal of Virology. 75: 799-808. PMID 11134293 DOI: 10.1128/Jvi.75.2.799-808.2001 |
0.553 |
|
2000 |
Yee C, Thompson JA, Roche P, Byrd DR, Lee PP, Piepkorn M, Kenyon K, Davis MM, Riddell SR, Greenberg PD. Melanocyte destruction after antigen-specific immunotherapy of melanoma: Direct evidence of T cell-mediated vitiligo Journal of Experimental Medicine. 192: 1637-1643. PMID 11104805 DOI: 10.1084/Jem.192.11.1637 |
0.6 |
|
2000 |
Cooper LJ, Kalos M, Lewinsohn DA, Riddell SR, Greenberg PD. Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes. Journal of Virology. 74: 8207-12. PMID 10933734 DOI: 10.1128/Jvi.74.17.8207-8212.2000 |
0.526 |
|
2000 |
Riddell SR, Greenberg PD. T-cell therapy of cytomegalovirus and human immunodeficiency virus infection. The Journal of Antimicrobial Chemotherapy. 35-43. PMID 10855770 DOI: 10.1093/JAC/45.SUPPL_4.35 |
0.42 |
|
2000 |
Berger C, Xuereb S, Johnson DC, Watanabe KS, Kiem HP, Greenberg PD, Riddell SR. Expression of herpes simplex virus ICP47 and human cytomegalovirus US11 prevents recognition of transgene products by CD8(+) cytotoxic T lymphocytes. Journal of Virology. 74: 4465-73. PMID 10775582 DOI: 10.1128/Jvi.74.10.4465-4473.2000 |
0.522 |
|
2000 |
Warren EH, Gavin MA, Simpson E, Chandler P, Page DC, Disteche C, Stankey KA, Greenberg PD, Riddell SR. The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen. Journal of Immunology (Baltimore, Md. : 1950). 164: 2807-14. PMID 10679124 DOI: 10.4049/Jimmunol.164.5.2807 |
0.341 |
|
2000 |
Lord JD, McIntosh BC, Greenberg PD, Nelson BH. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5. Journal of Immunology (Baltimore, Md. : 1950). 164: 2533-41. PMID 10679091 DOI: 10.4049/Jimmunol.164.5.2533 |
0.316 |
|
1999 |
Mossman SP, Pierce CC, Robertson MN, Watson AJ, Montefiori DC, Rabin M, Kuller L, Thompson J, Lynch JB, Morton WR, Benveniste RE, Munn R, Hu SL, Greenberg P, Haigwood NL. Immunization against SIVmne in macaques using multigenic DNA vaccines. Journal of Medical Primatology. 28: 206-13. PMID 10593487 DOI: 10.1111/J.1600-0684.1999.Tb00271.X |
0.45 |
|
1999 |
Mulvania T, Lynch JB, Robertson MN, Greenberg PD, Morton WR, Mullins JI. Antigen-specific cytokine responses in vaccinated Macaca nemestrina Journal of Medical Primatology. 28: 181-189. PMID 10593484 DOI: 10.1111/J.1600-0684.1999.Tb00268.X |
0.443 |
|
1999 |
Evans LS, Witte PR, Feldhaus AL, Nelson BH, Riddell SR, Greenberg PD, Lupton SD, Jones LA. Expression of chimeric granulocyte-macrophage colony-stimulating factor/interleukin 2 receptors in human cytotoxic T lymphocyte clones results in granulocyte-macrophage colony-stimulating factor-dependent growth. Human Gene Therapy. 10: 1941-51. PMID 10466628 DOI: 10.1089/10430349950017301 |
0.501 |
|
1999 |
Greenberg PD, Riddell SR. Deficient cellular immunity--finding and fixing the defects. Science (New York, N.Y.). 285: 546-51. PMID 10417377 DOI: 10.1126/Science.285.5427.546 |
0.518 |
|
1999 |
Bonnet D, Warren EH, Greenberg PD, Dick JE, Riddell SR. CD8(+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 8639-44. PMID 10411928 DOI: 10.1073/Pnas.96.15.8639 |
0.585 |
|
1999 |
Lee PP, Yee C, Savage PA, Fong L, Brockstedt D, Weber JS, Johnson D, Swetter S, Thompson J, Greenberg PD, Roederer M, Davis MM. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nature Medicine. 5: 677-85. PMID 10371507 DOI: 10.1038/9525 |
0.647 |
|
1999 |
Haigwood NL, Pierce CC, Robertson MN, Watson AJ, Montefiori DC, Rabin M, Lynch JB, Kuller L, Thompson J, Morton WR, Benveniste RE, Hu SL, Greenberg P, Mossman SP. Protection from pathogenic SIV challenge using multigenic DNA vaccines. Immunology Letters. 66: 183-8. PMID 10203053 DOI: 10.1016/S0165-2478(98)00156-4 |
0.354 |
|
1999 |
Brodie SJ, Lewinsohn DA, Patterson BK, Jiyamapa D, Krieger J, Corey L, Greenberg PD, Riddell SR. In vivo migration and function of transferred HIV-1-specific cytotoxic T cells. Nature Medicine. 5: 34-41. PMID 9883837 DOI: 10.1038/4716 |
0.358 |
|
1999 |
Warren EH, Gavin M, Greenberg PD, Riddell SR. Minor histocompatibility antigens as targets for T-cell therapy after bone marrow transplantation. Current Opinion in Hematology. 5: 429-33. PMID 9814651 DOI: 10.1097/00062752-199811000-00013 |
0.469 |
|
1998 |
Warren EH, Greenberg PD, Riddell SR. Cytotoxic T-Lymphocyte–Defined Human Minor Histocompatibility Antigens With a Restricted Tissue Distribution Blood. 91: 2197-2207. DOI: 10.1182/Blood.V91.6.2197 |
0.423 |
|
1997 |
Riddell SR, Greenberg PD. T cell therapy of human CMV and EBV infection in immunocompromised hosts. Reviews in Medical Virology. 7: 181-192. PMID 10398482 DOI: 10.1002/(Sici)1099-1654(199709)7:3<181::Aid-Rmv200>3.0.Co;2-W |
0.562 |
|
1997 |
Yee C, Riddell SR, Greenberg PD. Prospects for adoptive T cell therapy Current Opinion in Immunology. 9: 702-708. PMID 9368780 DOI: 10.1016/S0952-7915(97)80052-0 |
0.548 |
|
1997 |
Sing AP, Ambinder RF, Hong DJ, Jensen M, Batten W, Petersdorf E, Greenberg PD. Isolation of Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes that lyse Reed-Sternberg cells: Implications for immune-mediated therapy of EBV+ Hodgkin's disease Blood. 89: 1978-1986. PMID 9058719 DOI: 10.1182/Blood.V89.6.1978 |
0.547 |
|
1997 |
Nelson BH, McIntosh BC, Rosencrans LL, Greenberg PD. Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 94: 1878-83. PMID 9050873 DOI: 10.1073/Pnas.94.5.1878 |
0.338 |
|
1996 |
Gilbert MJ, Riddell SR, Plachter B, Greenberg PD. Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product. Nature. 383: 720-2. PMID 8878482 DOI: 10.1038/383720A0 |
0.491 |
|
1996 |
Kent SJ, Hu SL, Corey L, Morton WR, Greenberg PD. Detection of simian immunodeficiency virus (SIV)-specific CD8+ T cells in macaques protected from SIV challenge by prior SIV subunit vaccination. Journal of Virology. 70: 4941-7. PMID 8763998 DOI: 10.1128/Jvi.70.8.4941-4947.1996 |
0.444 |
|
1996 |
McElrath MJ, Corey L, Greenberg PD, Matthews TJ, Montefiori DC, Rowen L, Hood L, Mullins JI. Human immunodeficiency virus type 1 infection despite prior immunization with a recombinant envelope vaccine regimen. Proceedings of the National Academy of Sciences of the United States of America. 93: 3972-7. PMID 8633000 DOI: 10.1073/Pnas.93.9.3972 |
0.335 |
|
1996 |
Riddell SR, Elliott M, Lewinsohn DA, Gilbert MJ, Wilson L, Manley SA, Lupton SD, Overell RW, Reynolds TC, Corey L, Greenberg PD. T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nature Medicine. 2: 216-23. PMID 8574968 DOI: 10.1038/Nm0296-216 |
0.509 |
|
1996 |
Nelson BH, Lord JD, Greenberg PD. A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells. Molecular and Cellular Biology. 16: 309-17. PMID 8524310 DOI: 10.1128/Mcb.16.1.309 |
0.388 |
|
1995 |
Greenberg PD, Nelson B, Gilbert M, Sing A, Yee C, Jensen M, Riddell SR. Genetic modification of T cell clones to improve the safety and efficacy of adoptive T cell therapy. Ciba Foundation Symposium. 187: 212-23; discussion 2. PMID 7796672 DOI: 10.1002/9780470514672.ch14 |
0.549 |
|
1995 |
Walter EA, Greenberg PD, Gilbert MJ, Finch RJ, Watanabe KS, Thomas ED, Riddell SR. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. The New England Journal of Medicine. 333: 1038-44. PMID 7675046 DOI: 10.1056/Nejm199510193331603 |
0.82 |
|
1995 |
Riddell SR, Greenberg PD. Principles for adoptive T cell therapy of human viral diseases. Annual Review of Immunology. 13: 545-86. PMID 7612234 DOI: 10.1146/Annurev.Iy.13.040195.002553 |
0.563 |
|
1995 |
Riddell SR, Greenberg PD. Cellular adoptive immunotherapy after bone marrow transplantation. Cancer Treatment and Research. 76: 337-69. PMID 7577343 DOI: 10.1007/978-1-4615-2013-9_16 |
0.471 |
|
1994 |
McLaughlin-Taylor E, Pande H, Forman SJ, Tanamachi B, Li CR, Zaia JA, Greenberg PD, Riddell SR. Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8+ virus-specific cytotoxic T lymphocytes. Journal of Medical Virology. 43: 103-10. PMID 8083644 DOI: 10.1002/Jmv.1890430119 |
0.478 |
|
1994 |
McElrath MJ, Rabin M, Hoffman M, Klucking S, Garcia JV, Greenberg PD. Evaluation of human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T-lymphocyte responses utilizing B-lymphoblastoid cell lines transduced with the CD4 gene and infected with HIV-1. Journal of Virology. 68: 5074-83. PMID 8035507 DOI: 10.1128/Jvi.68.8.5074-5083.1994 |
0.385 |
|
1994 |
Riddell SR, Greenberg PD. Therapeutic reconstitution of human viral immunity by adoptive transfer of cytotoxic T lymphocyte clones. Current Topics in Microbiology and Immunology. 189: 9-34. PMID 7924439 DOI: 10.1007/978-3-642-78530-6_2 |
0.386 |
|
1994 |
Kent SJ, Stallard V, Corey L, Hu SL, Morton WR, Gritz L, Panicali DL, Greenberg PD. Analysis of cytotoxic T lymphocyte responses to SIV proteins in SIV-infected macaques using antigen-specific stimulation with recombinant vaccinia and fowl poxviruses. Aids Research and Human Retroviruses. 10: 551-60. PMID 7917517 DOI: 10.1089/Aid.1994.10.551 |
0.469 |
|
1994 |
McElrath MJ, Hoffman M, Kluckling S, Corey L, Greenberg PD. HIV-infected macrophages as efficient stimulator cells for detection of cytotoxic T cell responses to HIV in seronegative and seropositive vaccine recipients. Aids Research and Human Retroviruses. 10: 541-9. PMID 7917516 DOI: 10.1089/Aid.1994.10.541 |
0.356 |
|
1994 |
Nelson BH, Lord JD, Greenberg PD. Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation. Nature. 369: 333-6. PMID 7514277 DOI: 10.1038/369333A0 |
0.372 |
|
1994 |
Li C, Greenberg P, Gilbert M, Goodrich J, Riddell S. Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis Blood. 83: 1971-1979. DOI: 10.1182/Blood.V83.7.1971.Bloodjournal8371971 |
0.537 |
|
1993 |
Hu J, Kindsvogel W, Busby S, Bailey MC, Shi YY, Greenberg PD. An evaluation of the potential to use tumor-associated antigens as targets for antitumor T cell therapy using transgenic mice expressing a retroviral tumor antigen in normal lymphoid tissues. The Journal of Experimental Medicine. 177: 1681-90. PMID 8496686 DOI: 10.1084/Jem.177.6.1681 |
0.585 |
|
1993 |
Cooney EL, McElrath MJ, Corey L, Hu SL, Collier AC, Arditti D, Hoffman M, Coombs RW, Smith GE, Greenberg PD. Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein. Proceedings of the National Academy of Sciences of the United States of America. 90: 1882-6. PMID 8446603 DOI: 10.1073/Pnas.90.5.1882 |
0.397 |
|
1993 |
Riddell SR, Gilbert MJ, Greenberg PD. CD8+ cytotoxic T cell therapy of cytomegalovirus and HIV infection. Current Opinion in Immunology. 5: 484-91. PMID 8216922 DOI: 10.1016/0952-7915(93)90027-P |
0.545 |
|
1993 |
Gilbert MJ, Riddell SR, Li CR, Greenberg PD. Selective interference with class I major histocompatibility complex presentation of the major immediate-early protein following infection with human cytomegalovirus. Journal of Virology. 67: 3461-3469. DOI: 10.1128/Jvi.67.6.3461-3469.1993 |
0.403 |
|
1992 |
Schultz KR, Badger CC, Dombi GW, Greenberg PD, Bernstein ID. Effect of interleukin-2 on biodistribution of monoclonal antibody in tumor and normal tissues in mice bearing SL-2 thymoma. Journal of the National Cancer Institute. 84: 109-13. PMID 1735876 DOI: 10.1093/Jnci/84.2.109 |
0.392 |
|
1992 |
Riddell SR, Reusser P, Greenberg PD. Cytotoxic T cells specific for cytomegalovirus: a potential therapy for immunocompromised patients. Reviews of Infectious Diseases. S966-73. PMID 1664137 DOI: 10.1093/Clind/13.Supplement_11.S966 |
0.53 |
|
1992 |
Riddell SR, Greenberg PD, Overell RW, Loughran TP, Gilbert MJ, Lupton SD, Agosti J, Scheeler S, Coombs RW, Corey L. Phase I study of cellular adoptive immunotherapy using genetically modified CD8+ HIV-specific T cells for HIV seropositive patients undergoing allogeneic bone marrow transplant. The Fred Hutchinson Cancer Research Center and the University of Washington School of Medicine, Department of Medicine, Division of Oncology. Human Gene Therapy. 3: 319-38. PMID 1643151 DOI: 10.1089/Hum.1992.3.3-319 |
0.384 |
|
1992 |
Greenberg PD, Riddell SR. Tumor-specific T-cell immunity: ready for prime time? Journal of the National Cancer Institute. 84: 1059-61. PMID 1619675 DOI: 10.1093/Jnci/84.14.1059 |
0.564 |
|
1992 |
Riddell SR, Watanabe KS, Goodrich JM, Li CR, Agha ME, Greenberg PD. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones Science. 257: 238-241. PMID 1352912 DOI: 10.1126/Science.1352912 |
0.603 |
|
1991 |
Greenberg PD. Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells. Advances in Immunology. 49: 281-355. PMID 1853786 DOI: 10.1016/S0065-2776(08)60778-6 |
0.649 |
|
1991 |
Cooney EL, Collier AC, Greenberg PD, Coombs RW, Zarling J, Arditti DE, Hoffman MC, Hu SL, Corey L. Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein The Lancet. 337: 567-572. PMID 1671940 DOI: 10.1016/0140-6736(91)91636-9 |
0.37 |
|
1991 |
Greenberg PD, Reusser P, Goodrich JM, Riddell SR. Development of a treatment regimen for human cytomegalovirus (CMV) infection in bone marrow transplantation recipients by adoptive transfer of donor-derived CMV-specific T cell clones expanded in vitro Annals of the New York Academy of Sciences. 636: 184-195. PMID 1665321 DOI: 10.1111/J.1749-6632.1991.Tb33450.X |
0.428 |
|
1991 |
Reusser P, Riddell S, Meyers J, Greenberg P. Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease Blood. 78: 1373-1380. DOI: 10.1182/Blood.V78.5.1373.Bloodjournal7851373 |
0.44 |
|
1990 |
Schultz KR, Klarnet JP, Gieni RS, HayGlass KT, Greenberg PD. The role of B cells for in vivo T cell responses to a Friend virus-induced leukemia. Science (New York, N.Y.). 249: 921-3. PMID 2118273 DOI: 10.1126/Science.2118273 |
0.616 |
|
1990 |
Riddell SR, Greenberg PD. The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells. Journal of Immunological Methods. 128: 189-201. PMID 1691237 DOI: 10.1016/0022-1759(90)90210-M |
0.617 |
|
1989 |
Klarnet JP, Kern DE, Okuno K, Holt C, Lilly F, Greenberg PD. FBL-reactive CD8+ cytotoxic and CD4+ helper T lymphocytes recognize distinct Friend murine leukemia virus-encoded antigens. The Journal of Experimental Medicine. 169: 457-67. PMID 2562982 DOI: 10.1084/Jem.169.2.457 |
0.529 |
|
1988 |
Greenberg PD, Klarnet JP, Kern DE, Cheever MA. Therapy of disseminated tumors by adoptive transfer of specifically immune T cells. Progress in Experimental Tumor Research. 32: 104-27. PMID 3287447 DOI: 10.1159/000414675 |
0.546 |
|
1987 |
Cheever MA, Thompson JA, Peace DJ, Greenberg PD. Potential uses of interleukin 2 in cancer therapy. Immunobiology. 172: 365-82. PMID 3492434 DOI: 10.1016/S0171-2985(86)80118-8 |
0.513 |
|
1986 |
Cheever MA, Thompson DB, Klarnet JP, Greenberg PD. Antigen-driven long term-cultured T cells proliferate in vivo, distribute widely, mediate specific tumor therapy, and persist long-term as functional memory T cells. The Journal of Experimental Medicine. 163: 1100-12. PMID 3084700 DOI: 10.1084/Jem.163.5.1100 |
0.574 |
|
1986 |
Fefer A, Cheever MA, Greenberg PD. Identical-Twin (Syngeneic) Marrow Transplantation for Hematologic Cancers Journal of the National Cancer Institute. 76: 1269-1273. DOI: 10.1093/Jnci/76.6.1269 |
0.318 |
|
1985 |
Beatty PA, Greenberg PD, Cheever MA. Adoptive immunotherapy of metastatic B16 melanoma with allogeneic immune cells sensitized to minor histocompatibility antigens. Transplantation. 39: 182-6. PMID 3969713 DOI: 10.1097/00007890-198502000-00014 |
0.474 |
|
1985 |
Greenberg PD, Kern DE, Cheever MA. Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-1+,2- T cells. Tumor eradication does not require participation of cytotoxic T cells. The Journal of Experimental Medicine. 161: 1122-34. PMID 3921652 DOI: 10.1084/Jem.161.5.1122 |
0.635 |
|
1982 |
Cheever MA, Fefer A, Greenberg PD, Appelbaum F, Armitage JO, Buckner CD, Sale GE, Storb R, Witherspoon RP, Thomas ED. Treatment of hairy-cell leukemia with chemoradiotherapy and identical-twin bone-marrow transplantation. The New England Journal of Medicine. 307: 479-81. PMID 7048092 DOI: 10.1056/Nejm198208193070805 |
0.376 |
|
1982 |
Cheever MA, Greenberg PD, Fefer A, Gillis S. Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2. The Journal of Experimental Medicine. 155: 968-80. PMID 6977616 DOI: 10.1084/Jem.155.4.968 |
0.407 |
|
1981 |
Greenberg PD, Cheever MA, Fefer A. Eradication of disseminated murine leukemia by chemoimmunotherapy with cyclophosphamide and adoptively transferred immune syngeneic Lyt-1+2- lymphocytes. The Journal of Experimental Medicine. 154: 952-63. PMID 6974221 DOI: 10.1084/Jem.154.3.952 |
0.602 |
|
1981 |
Cheever MA, Greenberg PD, Fefer A. Chemoimmunotherapy of a Friend Leukemia With Cells Secondarily Sensitized In Vitro: Effect of Culture Duration on Therapeutic Efficacy Journal of the National Cancer Institute. 67: 169-173. DOI: 10.1093/Jnci/67.1.169 |
0.428 |
|
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