| Year |
Citation |
Score |
| 2024 |
Banerjee R, Zhu Y, Brownrigg GP, Moravcova R, Rogalski JC, Foster LJ, Johnson JD, Kolic J. Beta-hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets. Endocrinology. PMID 38970533 DOI: 10.1210/endocr/bqae079 |
0.425 |
|
| 2024 |
Kolic J, Sun WG, Cen HH, Ewald JD, Rogalski JC, Sasaki S, Sun H, Rajesh V, Xia YH, Moravcova R, Skovsø S, Spigelman AF, Manning Fox JE, Lyon J, Beet L, ... ... Johnson JD, et al. Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Cell Metabolism. 36: 1619-1633.e5. PMID 38959864 DOI: 10.1016/j.cmet.2024.06.001 |
0.38 |
|
| 2024 |
Mittendorfer B, Johnson JD, Solinas G, Jansson PA. Insulin Hypersecretion as Promoter of Body Fat Gain and Hyperglycemia. Diabetes. 73: 837-843. PMID 38768368 DOI: 10.2337/dbi23-0035 |
0.356 |
|
| 2024 |
Boothe T, Lim GE, Cen H, Skovsø S, Piske M, Li SN, Nabi IR, Gilon P, Johnson JD. Corrigendum to "Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells" [Mol Metab 2016 May; 5 (5): 366-378]. Molecular Metabolism. 101935. PMID 38604236 DOI: 10.1016/j.molmet.2024.101935 |
0.734 |
|
| 2024 |
Kolic J, Sun WG, Cen HH, Ewald J, Rogalski JC, Sasaki S, Sun H, Rajesh V, Xia YH, Moravcova R, Skovsø S, Spigelman AF, Manning Fox JE, Lyon J, Beet L, ... ... Johnson JD, et al. Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Medrxiv : the Preprint Server For Health Sciences. PMID 38496562 DOI: 10.1101/2023.05.24.23290298 |
0.379 |
|
| 2023 |
Kolic J, Sun WG, Johnson JD, Guess N. Amino acid-stimulated insulin secretion: a path forward in type 2 diabetes. Amino Acids. PMID 37966501 DOI: 10.1007/s00726-023-03352-8 |
0.387 |
|
| 2023 |
Zhang AMY, Xia YH, Lin JSH, Chu KH, Wang WCK, Ruiter TJJ, Yang JCC, Chen N, Chhuor J, Patil S, Cen HH, Rideout EJ, Richard VR, Schaeffer DF, Zahedi RP, ... ... Johnson JD, et al. Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation. Cell Metabolism. PMID 37913768 DOI: 10.1016/j.cmet.2023.10.003 |
0.389 |
|
| 2022 |
Chu CMJ, Modi H, Ellis C, Krentz NAJ, Skovsø S, Zhao YB, Cen H, Noursadeghi N, Panzhinskiy E, Hu X, Dionne DA, Xia YH, Xuan S, Huising MO, Kieffer TJ, ... ... Johnson JD, et al. Dynamic Ins2 Gene Activity Defines β-cell Maturity States. Diabetes. PMID 36170671 DOI: 10.2337/db21-1065 |
0.335 |
|
| 2022 |
Skovsø S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, ... ... Johnson JD, et al. Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance. Nature Communications. 13: 735. PMID 35136059 DOI: 10.1038/s41467-022-28039-8 |
0.759 |
|
| 2022 |
Cen HH, Hussein B, Botezelli JD, Wang S, Zhang JA, Noursadeghi N, Jessen N, Rodrigues B, Timmons JA, Johnson JD. Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22088. PMID 34921686 DOI: 10.1096/fj.202100497RR |
0.422 |
|
| 2021 |
Johnson JD. On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes. Diabetologia. PMID 34296322 DOI: 10.1007/s00125-021-05505-4 |
0.342 |
|
| 2021 |
Yong J, Johnson JD, Arvan P, Han J, Kaufman RJ. Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus. Nature Reviews. Endocrinology. PMID 34163039 DOI: 10.1038/s41574-021-00510-4 |
0.319 |
|
| 2021 |
Zhang AMY, Wellberg EA, Kopp JL, Johnson JD. Hyperinsulinemia in Obesity, Inflammation, and Cancer. Diabetes & Metabolism Journal. PMID 33775061 DOI: 10.4093/dmj.2020.0250 |
0.375 |
|
| 2020 |
Kolic J, Beet L, Overby P, Cen HH, Panzhinskiy E, Ure DR, Cross JL, Huizinga RB, Johnson JD. Differential effects of voclosporin and tacrolimus on insulin secretion from human islets. Endocrinology. PMID 32894758 DOI: 10.1210/Endocr/Bqaa162 |
0.506 |
|
| 2020 |
Jara MA, Werneck-De-Castro JP, Lubaczeuski C, Johnson JD, Bernal-Mizrachi E. Pancreatic and duodenal homeobox-1 (PDX1) contributes to β-cell mass expansion and proliferation induced by Akt/PKB pathway. Islets. 12: 32-40. PMID 32876522 DOI: 10.1080/19382014.2020.1762471 |
0.427 |
|
| 2020 |
Botezelli JD, Overby P, Lindo L, Wang S, Haïda O, Lim GE, Templeman NM, Pauli JR, Johnson JD. Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 32715748 DOI: 10.1152/Ajpendo.00128.2020 |
0.818 |
|
| 2020 |
Lee J, Kim K, Cho JH, Bae JY, O'Leary TP, Johnson JD, Bae YC, Kim EK. Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production. Jci Insight. PMID 32644973 DOI: 10.1172/Jci.Insight.135412 |
0.496 |
|
| 2020 |
Ramzy A, Tudurí E, Glavas MM, Baker RK, Mojibian M, Fox JK, O'Dwyer SM, Dai D, Hu X, Denroche HC, Edeer N, Gray SL, Verchere CB, Johnson JD, Kieffer TJ. AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects. Scientific Reports. 10: 10518. PMID 32601405 DOI: 10.1038/S41598-020-67136-W |
0.404 |
|
| 2020 |
Ludwig DS, Ebbeling CB, Bikman BT, Johnson JD. Testing the carbohydrate-insulin model in mice: The importance of distinguishing primary hyperinsulinemia from insulin resistance and metabolic dysfunction. Molecular Metabolism. 100960. PMID 32199816 DOI: 10.1016/J.Molmet.2020.02.003 |
0.495 |
|
| 2020 |
Baehring SK, O’Leary TP, Holenka DM, Li H, Kim K, Mehran AE, Pavlidis P, Kim E, Bamji SX, Johnson JD. SUN-240 Female Mice Lacking Brain Insulin Production Exhibit Learning Deficits, Anxiety, and Reduced Hippocampal Cyclin D1 Expression Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1066 |
0.415 |
|
| 2020 |
Kolic J, Zhu S, Johnson J. 78 - β-Hydroxybutyrate Acutely Promotes Basal Insulin Secretion From Human Islets Canadian Journal of Diabetes. 44: S31. DOI: 10.1016/j.jcjd.2020.08.084 |
0.347 |
|
| 2020 |
Panzhinskiy E, Huang H, Macdonald K, Johnson J, Lynn FC. 20 - CRISPR-Cas9 Optogenetic System for Insulin Expression in Human Embryonic Stem Cell-Derived β-Like Cells Canadian Journal of Diabetes. 44: S8. DOI: 10.1016/j.jcjd.2020.08.024 |
0.316 |
|
| 2019 |
Durrer C, McKelvey S, Singer J, Batterham AM, Johnson JD, Wortman J, Little JP. Pharmacist-led therapeutic carbohydrate restriction as a treatment strategy for type 2 diabetes: the Pharm-TCR randomized controlled trial protocol. Trials. 20: 781. PMID 31881991 DOI: 10.1186/S13063-019-3873-7 |
0.322 |
|
| 2019 |
Tudurí E, Glavas MM, Asadi A, Baker RK, Ellis CE, Soukhatcheva G, Philit M, Huynh FK, Johnson JD, Bruce Verchere C, Kieffer TJ. AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells. Scientific Reports. 9: 10829. PMID 31346189 DOI: 10.1038/S41598-019-46735-2 |
0.406 |
|
| 2019 |
Glavas MM, Hui Q, Tudurí E, Erener S, Kasteel NL, Johnson JD, Kieffer TJ. Early overnutrition reduces Pdx1 expression and induces β cell failure in Swiss Webster mice. Scientific Reports. 9: 3619. PMID 30842440 DOI: 10.1038/S41598-019-39177-3 |
0.406 |
|
| 2018 |
Modi H, Johnson JD. Folding mutations suppress early beta-cell proliferation. Elife. 7. PMID 30547883 DOI: 10.7554/Elife.43475 |
0.359 |
|
| 2018 |
Myette-Côté É, Durrer C, Neudorf H, Bammert TD, Botezelli JD, Johnson JD, DeSouza CA, Little JP. Short-term low-carbohydrate high-fat diet with or without post-meal walks on glycemic control and inflammation in type 2 diabetes: A randomized trial. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30303707 DOI: 10.1152/Ajpregu.00240.2018 |
0.301 |
|
| 2018 |
Lei CL, Kellard JA, Hara M, Johnson JD, Rodriguez B, Briant LJB. Beta-cell hubs maintain Ca oscillations in human and mouse islet simulations. Islets. 10: 151-167. PMID 30142036 DOI: 10.1080/19382014.2018.1493316 |
0.453 |
|
| 2018 |
Page MM, Johnson JD. Mild Suppression of Hyperinsulinemia to Treat Obesity and Insulin Resistance. Trends in Endocrinology and Metabolism: Tem. PMID 29665988 DOI: 10.1016/J.Tem.2018.03.018 |
0.445 |
|
| 2018 |
Lee JTC, Shanina I, Chu YN, Horwitz MS, Johnson JD. Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice. Scientific Reports. 8: 4588. PMID 29545618 DOI: 10.1038/s41598-018-23026-w |
0.302 |
|
| 2018 |
Dommerholt MB, Dionne DA, Hutchinson DF, Kruit JK, Johnson JD. Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage. The Journal of Endocrinology. PMID 29439088 DOI: 10.1530/Joe-17-0505 |
0.517 |
|
| 2017 |
Page MM, Skovsø S, Cen H, Chiu AP, Dionne DA, Hutchinson DF, Lim GE, Szabat M, Flibotte S, Sinha S, Nislow C, Rodrigues B, Johnson JD. Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29122848 DOI: 10.1096/Fj.201700518R |
0.748 |
|
| 2017 |
Huynh FK, Hu X, Lin Z, Johnson JD, Hirschey MD. Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds. Journal of Inherited Metabolic Disease. PMID 28726069 DOI: 10.1007/S10545-017-0069-8 |
0.48 |
|
| 2017 |
Templeman NM, Flibotte S, Chik JHL, Sinha S, Lim GE, Foster LJ, Nislow C, Johnson JD. Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan. Cell Reports. 20: 451-463. PMID 28700945 DOI: 10.1016/J.Celrep.2017.06.048 |
0.831 |
|
| 2017 |
Axelsson AS, Mahdi T, Nenonen HA, Singh T, Hänzelmann S, Wendt A, Bagge A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Szabat M, Tang Y, ... ... Johnson JD, et al. Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes. Nature Communications. 8: 15652. PMID 28585545 DOI: 10.1038/Ncomms15652 |
0.528 |
|
| 2017 |
Templeman NM, Skovsø S, Page MM, Lim GE, Johnson JD. A causal role for hyperinsulinemia in obesity. The Journal of Endocrinology. PMID 28052999 DOI: 10.1530/Joe-16-0449 |
0.829 |
|
| 2017 |
Zhang D, Wang F, Lal N, Chiu AP, Wan A, Jia J, Bierende D, Flibotte S, Sinha S, Asadi A, Hu X, Taghizadeh F, Pulinilkunnil T, Nislow C, Vlodavsky I, ... Johnson JD, et al. Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes. Diabetes. 66: 45-57. PMID 27999107 DOI: 10.2337/Db16-0761 |
0.519 |
|
| 2017 |
Mugabo Y, Lee JT, Fang NN, Acker-Palmer A, Mayor T, Johnson JD, Lim GE. Identification of Novel Adipogenic Factors in the 14–3-3ζ Interactome During Adipocyte Differentiation Canadian Journal of Diabetes. 41. DOI: 10.1016/J.Jcjd.2017.08.203 |
0.645 |
|
| 2017 |
Kolic J, Skovsø S, Spigelman A, Fox JM, Lyon J, Ao Z, Warnock G, Macdonald P, Johnson J. Human Islets Exhibit Variability in Macronutrient-Stimulated Insulin Release that Cannot be Explained by Gross Donor Characteristics Canadian Journal of Diabetes. 41. DOI: 10.1016/J.Jcjd.2017.08.038 |
0.427 |
|
| 2016 |
D'souza AM, Johnson JD, Clee SM, Kieffer TJ. Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lep(ob/ob) mice. Molecular Metabolism. 5: 1103-1112. PMID 27818936 DOI: 10.1016/J.Molmet.2016.09.007 |
0.486 |
|
| 2016 |
Kolic J, Johnson JD. Specialized Hub Beta Cells Trade Maximal Insulin Production for Perfect Timing. Cell Metabolism. 24: 371-373. PMID 27626196 DOI: 10.1016/J.Cmet.2016.08.022 |
0.517 |
|
| 2016 |
Johnson JD. The quest to make fully functional human pancreatic beta cells from embryonic stem cells: climbing a mountain in the clouds. Diabetologia. PMID 27473069 DOI: 10.1007/S00125-016-4059-4 |
0.41 |
|
| 2016 |
Lim GE, Johnson JD. 14-3-3ζ: A numbers game in adipocyte function? Adipocyte. 5: 232-237. PMID 27386155 DOI: 10.1080/21623945.2015.1120913 |
0.668 |
|
| 2016 |
Lim GE, Piske M, Lulo JE, Ramshaw HS, Lopez AF, Johnson JD. Ywhaz/14-3-3ζ deletion improves glucose tolerance through a GLP-1-dependent mechanism. Endocrinology. en20161016. PMID 27167773 DOI: 10.1210/En.2016-1016 |
0.748 |
|
| 2016 |
Dionne DA, Skovsø S, Templeman NM, Clee SM, Johnson JD. Caloric restriction paradoxically increases adiposity in mice with genetically reduced insulin. Endocrinology. en20161102. PMID 27145011 DOI: 10.1210/En.2016-1102 |
0.789 |
|
| 2016 |
Boothe T, Lim GE, Cen H, Skovsø S, Piske M, Li SN, Nabi IR, Gilon P, Johnson JD. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Molecular Metabolism. 5: 366-78. PMID 27110488 DOI: 10.1016/J.Molmet.2016.01.009 |
0.759 |
|
| 2016 |
Templeman NM, Mehran AE, Johnson JD. Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility. Plos One. 11: e0153280. PMID 27055260 DOI: 10.1371/Journal.Pone.0153280 |
0.795 |
|
| 2016 |
Wills QF, Boothe T, Asadi A, Ao Z, Warnock GL, Kieffer TJ, Johnson JD. Statistical approaches and software for clustering islet cell functional heterogeneity. Islets. 0. PMID 26909740 DOI: 10.1080/19382014.2016.1150664 |
0.347 |
|
| 2016 |
Skovsø S, Dionne DA, Li H, Hutchinson D, Hu X, Johnson JD. Effects of Beta-Cell-Specific Insulin Resistance on Glucose Homeostasis and Body Weight Image 12 Canadian Journal of Diabetes. 40. DOI: 10.1016/J.Jcjd.2016.08.170 |
0.493 |
|
| 2016 |
Johnson JD, Templeman NM. Hyperinsulinemia Causes Age-Dependent Insulin Resistance and Reduces Lifespan Image 10 Canadian Journal of Diabetes. 40. DOI: 10.1016/J.Jcjd.2016.08.167 |
0.773 |
|
| 2016 |
Panzhinskiy E, Taghizadeh F, Chu KY, Yang YH, Jan E, Johnson J. Eukaryotic Translation Initiation Factor 2A (eIF2A) Protects Pancreatic Beta Cells During ER Stress-Induced Apoptosis Image 6 Canadian Journal of Diabetes. 40. DOI: 10.1016/J.Jcjd.2016.08.038 |
0.339 |
|
| 2015 |
Szabat M, Modi H, Ramracheya R, Girbinger V, Chan F, Lee JT, Piske M, Kamal S, Carol Yang YH, Welling A, Rorsman P, Johnson JD. High-content screening identifies a role for Na(+) channels in insulin production. Royal Society Open Science. 2: 150306. PMID 27019722 DOI: 10.1098/Rsos.150306 |
0.476 |
|
| 2015 |
Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, ... ... Johnson JD, et al. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation. Cell Metabolism. PMID 26626461 DOI: 10.1016/J.Cmet.2015.10.016 |
0.493 |
|
| 2015 |
Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD. 14-3-3ζ coordinates adipogenesis of visceral fat. Nature Communications. 6: 7671. PMID 26220403 DOI: 10.1038/Ncomms8671 |
0.712 |
|
| 2015 |
Templeman NM, Clee SM, Johnson JD. Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity. Diabetologia. PMID 26155745 DOI: 10.1007/S00125-015-3676-7 |
0.79 |
|
| 2015 |
Yang YH, Wills QF, Johnson JD. A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells. Diabetologia. 58: 1239-49. PMID 25773404 DOI: 10.1007/S00125-015-3552-5 |
0.389 |
|
| 2015 |
Ho MM, Johnson JD, Clee SM. PWD/PhJ mice have a genetically determined increase in nutrient-stimulated insulin secretion. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 26: 131-41. PMID 25605412 DOI: 10.1007/S00335-015-9554-2 |
0.528 |
|
| 2014 |
Chan MT, Lim GE, Skovsø S, Yang YH, Albrecht T, Alejandro EU, Hoesli CA, Piret JM, Warnock GL, Johnson JD. Effects of insulin on human pancreatic cancer progression modeled in vitro. Bmc Cancer. 14: 814. PMID 25373319 DOI: 10.1186/1471-2407-14-814 |
0.788 |
|
| 2014 |
Johnson JD. A practical guide to genetic engineering of pancreatic β-cells in vivo: getting a grip on RIP and MIP. Islets. 6: e944439. PMID 25322827 DOI: 10.4161/19382014.2014.944439 |
0.328 |
|
| 2014 |
Rezania A, Bruin JE, Arora P, Rubin A, Batushansky I, Asadi A, O'Dwyer S, Quiskamp N, Mojibian M, Albrecht T, Yang YH, Johnson JD, Kieffer TJ. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nature Biotechnology. 32: 1121-33. PMID 25211370 DOI: 10.1038/Nbt.3033 |
0.53 |
|
| 2014 |
Liu Y, Wang R, Sun B, Mi T, Zhang J, Mu Y, Chen J, Bround MJ, Johnson JD, Gillis AM, Chen SR. Generation and characterization of a mouse model harboring the exon-3 deletion in the cardiac ryanodine receptor. Plos One. 9: e95615. PMID 24743769 DOI: 10.1371/Journal.Pone.0095615 |
0.307 |
|
| 2014 |
Ho MM, Hu X, Karunakaran S, Johnson JD, Clee SM. Altered pancreatic growth and insulin secretion in WSB/EiJ mice. Plos One. 9: e88352. PMID 24505481 DOI: 10.1371/Journal.Pone.0088352 |
0.505 |
|
| 2014 |
D'souza AM, Asadi A, Johnson JD, Covey SD, Kieffer TJ. Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis. Endocrinology. 155: 1268-79. PMID 24467741 DOI: 10.1210/En.2013-1523 |
0.482 |
|
| 2014 |
Yang YH, Vilin YY, Roberge M, Kurata HT, Johnson JD. Multiparameter screening reveals a role for Na+ channels in cytokine-induced β-cell death. Molecular Endocrinology (Baltimore, Md.). 28: 406-17. PMID 24438339 DOI: 10.1210/Me.2013-1257 |
0.331 |
|
| 2014 |
Bruin JE, Erener S, Vela J, Hu X, Johnson JD, Kurata HT, Lynn FC, Piret JM, Asadi A, Rezania A, Kieffer TJ. Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells. Stem Cell Research. 12: 194-208. PMID 24257076 DOI: 10.1016/J.Scr.2013.10.003 |
0.454 |
|
| 2013 |
Szabat M, Johnson JD. Modulation of β-cell fate and function by TGFβ ligands: a superfamily with many powers. Endocrinology. 154: 3965-9. PMID 24141995 DOI: 10.1210/En.2013-1880 |
0.457 |
|
| 2013 |
Yang YH, Manning Fox JE, Zhang KL, MacDonald PE, Johnson JD. Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 110: 16480-5. PMID 24065825 DOI: 10.1073/Pnas.1214312110 |
0.489 |
|
| 2013 |
Tudurí E, Bruin JE, Denroche HC, Fox JK, Johnson JD, Kieffer TJ. Impaired Ca(2+) signaling in β-cells lacking leptin receptors by Cre-loxP recombination. Plos One. 8: e71075. PMID 23936486 DOI: 10.1371/Journal.Pone.0071075 |
0.556 |
|
| 2013 |
Yang YH, Johnson JD. Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic β-cells. Journal of Cell Science. 126: 4286-95. PMID 23843629 DOI: 10.1242/Jcs.133017 |
0.347 |
|
| 2013 |
Wang M, Li J, Lim GE, Johnson JD. Is dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets. Plos One. 8: e64860. PMID 23798995 DOI: 10.1371/Journal.Pone.0064860 |
0.771 |
|
| 2013 |
Bround MJ, Wambolt R, Luciani DS, Kulpa JE, Rodrigues B, Brownsey RW, Allard MF, Johnson JD. Cardiomyocyte ATP production, metabolic flexibility, and survival require calcium flux through cardiac ryanodine receptors in vivo. The Journal of Biological Chemistry. 288: 18975-86. PMID 23678000 DOI: 10.1074/Jbc.M112.427062 |
0.684 |
|
| 2013 |
Ho MM, Yoganathan P, Chu KY, Karunakaran S, Johnson JD, Clee SM. Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets. Bmc Genetics. 14: 10. PMID 23442068 DOI: 10.1186/1471-2156-14-10 |
0.377 |
|
| 2013 |
Lim GE, Piske M, Johnson JD. 14-3-3 proteins are essential signalling hubs for beta cell survival. Diabetologia. 56: 825-37. PMID 23354124 DOI: 10.1007/S00125-012-2820-X |
0.734 |
|
| 2013 |
Luciani DS, White SA, Widenmaier SB, Saran VV, Taghizadeh F, Hu X, Allard MF, Johnson JD. Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic β-cells. Diabetes. 62: 170-82. PMID 22933114 DOI: 10.2337/Db11-1464 |
0.748 |
|
| 2013 |
Lim GE, Ramshaw HS, Clee SM, Guthridge MA, Lopez AF, Johnson JD. 14-3-3zeta Regulates Adipogenesis, Glucose Tolerance and Insulin Sensitivity in Mice Canadian Journal of Diabetes. 37: S9. DOI: 10.1016/J.Jcjd.2013.08.024 |
0.763 |
|
| 2012 |
Mehran AE, Templeman NM, Brigidi GS, Lim GE, Chu KY, Hu X, Botezelli JD, Asadi A, Hoffman BG, Kieffer TJ, Bamji SX, Clee SM, Johnson JD. Hyperinsulinemia drives diet-induced obesity independently of brain insulin production. Cell Metabolism. 16: 723-37. PMID 23217255 DOI: 10.1016/J.Cmet.2012.10.019 |
0.811 |
|
| 2012 |
Szabat M, Lynn FC, Hoffman BG, Kieffer TJ, Allan DW, Johnson JD. Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiology. Diabetes. 61: 1365-71. PMID 22618775 DOI: 10.2337/Db11-1361 |
0.359 |
|
| 2012 |
Hoesli CA, Johnson JD, Piret JM. Purified human pancreatic duct cell culture conditions defined by serum-free high-content growth factor screening. Plos One. 7: e33999. PMID 22442738 DOI: 10.1371/Journal.Pone.0033999 |
0.333 |
|
| 2012 |
Kruit JK, Wijesekara N, Westwell-Roper C, Vanmierlo T, de Haan W, Bhattacharjee A, Tang R, Wellington CL, LütJohann D, Johnson JD, Brunham LR, Verchere CB, Hayden MR. Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function. Diabetes. 61: 659-64. PMID 22315310 DOI: 10.2337/Db11-1341 |
0.412 |
|
| 2012 |
Anand O, Almoazen H, Mehrotra N, Johnson J, Shukla A. Controlled release of modified insulin glargine from novel biodegradable injectable gels. Aaps Pharmscitech. 13: 313-22. PMID 22258803 DOI: 10.1208/S12249-011-9744-5 |
0.38 |
|
| 2012 |
Wang F, Wang Y, Zhang D, Puthanveetil P, Johnson JD, Rodrigues B. Fatty acid-induced nuclear translocation of heparanase uncouples glucose metabolism in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 406-14. PMID 22116097 DOI: 10.1161/Atvbaha.111.240770 |
0.358 |
|
| 2012 |
Johnson JD, Bround MJ, White SA, Luciani DS. Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival. Protoplasma. 249: S49-58. PMID 22105567 DOI: 10.1007/S00709-011-0349-3 |
0.699 |
|
| 2012 |
Chu KY, Li H, Wada K, Johnson JD. Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions. Diabetologia. 55: 128-40. PMID 22038515 DOI: 10.1007/S00125-011-2323-1 |
0.36 |
|
| 2012 |
Yang YHC, Johnson JD. Multi-parameter Live Cell Tracking of Apoptotic and Non-apoptotic Beta-cell Death: High-content Screening for Factors that Prevent Beta-cell Apoptosis Canadian Journal of Diabetes. 36. DOI: 10.1016/J.Jcjd.2012.07.462 |
0.358 |
|
| 2012 |
Templeman NM, Mehran AE, Hu X, Clee SM, Johnson JD. Protection Against Diet-Induced Obesity Afforded by Reduced Circulating Insulin Levels is Linked to Increased Energy Expenditure and Browning of White Adipose Canadian Journal of Diabetes. 36: S68. DOI: 10.1016/J.Jcjd.2012.07.438 |
0.776 |
|
| 2012 |
Taghizadeh F, Chu C, Chu J, Johnson J, Jan E. Characterization of Translation Factors eIF2A and eIF2D During ER Stress in Pancreatic Beta-cells Canadian Journal of Diabetes. 36. DOI: 10.1016/J.Jcjd.2012.07.421 |
0.448 |
|
| 2012 |
Ho MM, Hu X, Chu KY, Karunakaran S, Johnson JD, Clee SM. Genetically Diverse PWD/PhJ Mice have Primary Hyperinsulinemia Arising from Enhanced Nutrient-stimulated Insulin Secretion Canadian Journal of Diabetes. 36: S62. DOI: 10.1016/J.Jcjd.2012.07.418 |
0.446 |
|
| 2012 |
White SA, Johnson JD, Luciani DS. Combined and Individual Roles of Bax and Bak in Beta-Cell Stress Signalling and Death Canadian Journal of Diabetes. 36. DOI: 10.1016/J.Jcjd.2012.07.415 |
0.694 |
|
| 2012 |
Albrecht T, Lim GE, Nabi IR, Johnson JD. Caveolin-1 Mediates the Internalization of Functional Insulin Receptors in Beta-Cells Canadian Journal of Diabetes. 36. DOI: 10.1016/J.Jcjd.2012.07.409 |
0.757 |
|
| 2012 |
Bround MJ, Asghari P, Wambolt R, Bohunek L, Luciani DS, Taghizadeh F, Kulpa JE, Boheler KR, Rodrigues B, Brownsey RW, Moore ED, Allard MF, Johnson JD. Acute Cardiac Ryanodine Receptor Loss-of-Function Leads to Cardiomyopathy and Metabolic Dysfunction: Implications for Diabetes Complications Canadian Journal of Diabetes. 36: S52. DOI: 10.1016/J.Jcjd.2012.07.379 |
0.642 |
|
| 2012 |
Lim GE, Piske M, Ramshaw HS, Guthridge MA, Lopez AF, Johnson JD. 14-3-3 Zeta is Required for Insulin Sensitivity and Glucose Homeostasis In Vivo Canadian Journal of Diabetes. 36. DOI: 10.1016/J.Jcjd.2012.07.077 |
0.738 |
|
| 2012 |
Bround M, Asghari P, Luciani D, Taghizadeh F, Bohunek L, Wambolt R, Smits C, Kulpa J, Lakatta E, Boheler K, Rodrigues B, Brownsey R, Moore E, Allard M, Johnson J. 463 Acute Cardiac Ryanodine Receptor Loss-of-Function Leads to Bradycardia, Arrhythmia, Heart Failure and Transcriptional Metabolic Reprogramming Canadian Journal of Cardiology. 28: S270. DOI: 10.1016/J.Cjca.2012.07.426 |
0.614 |
|
| 2011 |
Szabat M, Kalynyak TB, Lim GE, Chu KY, Yang YH, Asadi A, Gage BK, Ao Z, Warnock GL, Piret JM, Kieffer TJ, Johnson JD. Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes. Cell Death & Disease. 2: e232. PMID 22113197 DOI: 10.1038/Cddis.2011.119 |
0.749 |
|
| 2011 |
Kruit JK, Wijesekara N, Fox JE, Dai XQ, Brunham LR, Searle GJ, Morgan GP, Costin AJ, Tang R, Bhattacharjee A, Johnson JD, Light PE, Marsh BJ, Macdonald PE, Verchere CB, et al. Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules. Diabetes. 60: 3186-96. PMID 21998401 DOI: 10.2337/Db11-0081 |
0.495 |
|
| 2011 |
Alejandro EU, Lim GE, Mehran AE, Hu X, Taghizadeh F, Pelipeychenko D, Baccarini M, Johnson JD. Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3884-95. PMID 21817126 DOI: 10.1096/Fj.10-180349 |
0.845 |
|
| 2011 |
Szabat M, Pourghaderi P, Soukhatcheva G, Verchere CB, Warnock GL, Piret JM, Johnson JD. Kinetics and genomic profiling of adult human and mouse β-cell maturation. Islets. 3: 175-87. PMID 21633187 DOI: 10.4161/Isl.3.4.15881 |
0.347 |
|
| 2011 |
Chu KY, Briggs MJ, Albrecht T, Drain PF, Johnson JD. Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells. Islets. 3: 155-65. PMID 21628999 DOI: 10.4161/Isl.3.4.15767 |
0.524 |
|
| 2011 |
Gallo M, Park D, Luciani DS, Kida K, Palmieri F, Blacque OE, Johnson JD, Riddle DL. MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. Plos One. 6: e17827. PMID 21448454 DOI: 10.1371/Journal.Pone.0017827 |
0.711 |
|
| 2011 |
Yang YH, Szabat M, Bragagnini C, Kott K, Helgason CD, Hoffman BG, Johnson JD. Paracrine signalling loops in adult human and mouse pancreatic islets: netrins modulate beta cell apoptosis signalling via dependence receptors. Diabetologia. 54: 828-42. PMID 21212933 DOI: 10.1007/S00125-010-2012-5 |
0.461 |
|
| 2011 |
Hoesli CA, Raghuram K, Kiang RL, Mocinecová D, Hu X, Johnson JD, Lacík I, Kieffer TJ, Piret JM. Pancreatic cell immobilization in alginate beads produced by emulsion and internal gelation. Biotechnology and Bioengineering. 108: 424-34. PMID 20939004 DOI: 10.1002/Bit.22959 |
0.433 |
|
| 2010 |
Hutton MJ, Soukhatcheva G, Johnson JD, Verchere CB. Role of the TLR signaling molecule TRIF in β-cell function and glucose homeostasis. Islets. 2: 104-11. PMID 21099302 DOI: 10.4161/Isl.2.2.11209 |
0.477 |
|
| 2010 |
Hill JA, Szabat M, Hoesli CA, Gage BK, Yang YH, Williams DE, Riedel MJ, Luciani DS, Kalynyak TB, Tsai K, Ao Z, Andersen RJ, Warnock GL, Piret JM, Kieffer TJ, ... Johnson JD, et al. A multi-parameter, high-content, high-throughput screening platform to identify natural compounds that modulate insulin and Pdx1 expression. Plos One. 5: e12958. PMID 20886041 DOI: 10.1371/Journal.Pone.0012958 |
0.775 |
|
| 2010 |
Chu KY, Lin Y, Hendel A, Kulpa JE, Brownsey RW, Johnson JD. ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells. The Journal of Biological Chemistry. 285: 32606-15. PMID 20693577 DOI: 10.1074/Jbc.M110.157172 |
0.439 |
|
| 2010 |
Bernal-Mizrachi E, Cras-Méneur C, Ye BR, Johnson JD, Permutt MA. Transgenic overexpression of active calcineurin in beta-cells results in decreased beta-cell mass and hyperglycemia. Plos One. 5: e11969. PMID 20689817 DOI: 10.1371/Journal.Pone.0011969 |
0.421 |
|
| 2010 |
Szabat M, Johnson JD, Piret JM. Reciprocal modulation of adult beta cell maturity by activin A and follistatin. Diabetologia. 53: 1680-9. PMID 20440469 DOI: 10.1007/S00125-010-1758-0 |
0.37 |
|
| 2010 |
Johnson JD, Luciani DS. Mechanisms of pancreatic beta-cell apoptosis in diabetes and its therapies. Advances in Experimental Medicine and Biology. 654: 447-62. PMID 20217509 DOI: 10.1007/978-90-481-3271-3_19 |
0.711 |
|
| 2010 |
Wang F, Wang Y, Kim MS, Puthanveetil P, Ghosh S, Luciani DS, Johnson JD, Abrahani A, Rodrigues B. Glucose-induced endothelial heparanase secretion requires cortical and stress actin reorganization. Cardiovascular Research. 87: 127-36. PMID 20164120 DOI: 10.1093/Cvr/Cvq051 |
0.704 |
|
| 2010 |
Alejandro EU, Kalynyak TB, Taghizadeh F, Gwiazda KS, Rawstron EK, Jacob KJ, Johnson JD. Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways. Endocrinology. 151: 502-12. PMID 20056832 DOI: 10.1210/En.2009-0678 |
0.769 |
|
| 2009 |
Li J, Johnson JD. MATHEMATICAL MODELS OF SUBCUTANEOUS INJECTION OF INSULIN ANALOGUES: A MINI-REVIEW. Discrete and Continuous Dynamical Systems. Series B. 12: 401-414. PMID 21572588 DOI: 10.3934/Dcdsb.2009.12.401 |
0.515 |
|
| 2009 |
Johnson JD, Otani K, Bell GI, Polonsky KS. Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic β-cells. Islets. 1: 242-8. PMID 21099278 DOI: 10.4161/Isl.1.3.9780 |
0.708 |
|
| 2009 |
Fujimoto K, Hanson PT, Tran H, Ford EL, Han Z, Johnson JD, Schmidt RE, Green KG, Wice BM, Polonsky KS. Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation. The Journal of Biological Chemistry. 284: 27664-73. PMID 19654319 DOI: 10.1074/Jbc.M109.041616 |
0.642 |
|
| 2009 |
Johnson JD, Ao Z, Ao P, Li H, Dai LJ, He Z, Tee M, Potter KJ, Klimek AM, Meloche RM, Thompson DM, Verchere CB, Warnock GL. Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets. Cell Transplantation. 18: 833-45. PMID 19500470 DOI: 10.3727/096368909X471198 |
0.505 |
|
| 2009 |
Kewalramani G, Puthanveetil P, Wang F, Kim MS, Deppe S, Abrahani A, Luciani DS, Johnson JD, Rodrigues B. AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death. Cardiovascular Research. 84: 42-53. PMID 19477967 DOI: 10.1093/Cvr/Cvp166 |
0.665 |
|
| 2009 |
Gwiazda KS, Yang TL, Lin Y, Johnson JD. Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells. American Journal of Physiology. Endocrinology and Metabolism. 296: E690-701. PMID 19141690 DOI: 10.1152/Ajpendo.90525.2008 |
0.37 |
|
| 2009 |
Johnson JD. Proteomic identification of carboxypeptidase E connects lipid-induced beta-cell apoptosis and dysfunction in type 2 diabetes. Cell Cycle (Georgetown, Tex.). 8: 38-42. PMID 19106615 DOI: 10.4161/Cc.8.1.7343 |
0.487 |
|
| 2009 |
Szabat M, Luciani DS, Piret JM, Johnson JD. Maturation of adult beta-cells revealed using a Pdx1/insulin dual-reporter lentivirus. Endocrinology. 150: 1627-35. PMID 19095744 DOI: 10.1210/En.2008-1224 |
0.762 |
|
| 2009 |
Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD. Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death. Diabetes. 58: 422-32. PMID 19033399 DOI: 10.2337/Db07-1762 |
0.689 |
|
| 2009 |
Chang JP, Johnson JD, Sawisky GR, Grey CL, Mitchell G, Booth M, Volk MM, Parks SK, Thompson E, Goss GG, Klausen C, Habibi HR. Signal transduction in multifactorial neuroendocrine control of gonadotropin secretion and synthesis in teleosts-studies on the goldfish model. General and Comparative Endocrinology. 161: 42-52. PMID 18838074 DOI: 10.1016/J.Ygcen.2008.09.005 |
0.307 |
|
| 2009 |
Walia P, Asadi A, Kieffer TJ, Johnson JD, Chanoine JP. Ontogeny of ghrelin, obestatin, preproghrelin, and prohormone convertases in rat pancreas and stomach. Pediatric Research. 65: 39-44. PMID 18784614 DOI: 10.1203/Pdr.0B013E31818Bc134 |
0.33 |
|
| 2008 |
Wang Y, Huang BP, Luciani DS, Wang X, Johnson JD, Proud CG. Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes. Journal of Molecular and Cellular Cardiology. 45: 812-20. PMID 18722381 DOI: 10.1016/J.Yjmcc.2008.07.016 |
0.671 |
|
| 2008 |
Jeffrey KD, Alejandro EU, Luciani DS, Kalynyak TB, Hu X, Li H, Lin Y, Townsend RR, Polonsky KS, Johnson JD. Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 8452-7. PMID 18550819 DOI: 10.1073/Pnas.0711232105 |
0.806 |
|
| 2008 |
Johnson JD, Alejandro EU. Control of pancreatic beta-cell fate by insulin signaling: The sweet spot hypothesis. Cell Cycle (Georgetown, Tex.). 7: 1343-7. PMID 18418065 DOI: 10.4161/Cc.7.10.5865 |
0.759 |
|
| 2008 |
Beith JL, Alejandro EU, Johnson JD. Insulin stimulates primary beta-cell proliferation via Raf-1 kinase. Endocrinology. 149: 2251-60. PMID 18202127 DOI: 10.1210/En.2007-1557 |
0.764 |
|
| 2008 |
Dror V, Kalynyak TB, Bychkivska Y, Frey MH, Tee M, Jeffrey KD, Nguyen V, Luciani DS, Johnson JD. Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells. The Journal of Biological Chemistry. 283: 9909-16. PMID 18174159 DOI: 10.1074/Jbc.M710601200 |
0.726 |
|
| 2008 |
Alejandro EU, Johnson JD. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. The Journal of Biological Chemistry. 283: 2407-17. PMID 18006502 DOI: 10.1074/Jbc.M703612200 |
0.69 |
|
| 2008 |
Luciani DS, Widenmaier S, Yeung J, Mcintosh C, Johnson JD. Subcellular Distribution and Function of Bcl-2 and BcI-xl in the β-cell Canadian Journal of Diabetes. 32: 337. DOI: 10.1016/S1499-2671(08)24148-1 |
0.656 |
|
| 2007 |
Dror V, Nguyen V, Walia P, Kalynyak TB, Hill JA, Johnson JD. Notch signalling suppresses apoptosis in adult human and mouse pancreatic islet cells. Diabetologia. 50: 2504-15. PMID 17922104 DOI: 10.1007/S00125-007-0835-5 |
0.401 |
|
| 2007 |
Luciani DS, Ao P, Hu X, Warnock GL, Johnson JD. Voltage-gated Ca(2+) influx and insulin secretion in human and mouse beta-cells are impaired by the mitochondrial Na(+)/Ca(2+) exchange inhibitor CGP-37157. European Journal of Pharmacology. 576: 18-25. PMID 17719029 DOI: 10.1016/J.Ejphar.2007.07.055 |
0.761 |
|
| 2007 |
Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, Marsh BJ, Rodrigues B, Johnson JD, Parks JS, Verchere CB, Hayden MR. Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nature Medicine. 13: 340-7. PMID 17322896 DOI: 10.1038/Nm1546 |
0.525 |
|
| 2007 |
Johnson JD. Pancreatic Beta-cell Apoptosis in Maturity Onset Diabetes of the Young Canadian Journal of Diabetes. 31: 67-74. DOI: 10.1016/S1499-2671(07)11013-3 |
0.39 |
|
| 2006 |
Johnson JD, Bernal-Mizrachi E, Alejandro EU, Han Z, Kalynyak TB, Li H, Beith JL, Gross J, Warnock GL, Townsend RR, Permutt MA, Polonsky KS. Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proceedings of the National Academy of Sciences of the United States of America. 103: 19575-80. PMID 17158802 DOI: 10.1073/Pnas.0604208103 |
0.813 |
|
| 2006 |
Johnson JD, Ford EL, Bernal-Mizrachi E, Kusser KL, Luciani DS, Han Z, Tran H, Randall TD, Lund FE, Polonsky KS. Suppressed insulin signaling and increased apoptosis in CD38-null islets. Diabetes. 55: 2737-46. PMID 17003338 DOI: 10.2337/Db05-1455 |
0.801 |
|
| 2006 |
Wideman RD, Yu IL, Webber TD, Verchere CB, Johnson JD, Cheung AT, Kieffer TJ. Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1). Proceedings of the National Academy of Sciences of the United States of America. 103: 13468-73. PMID 16938896 DOI: 10.1073/Pnas.0600655103 |
0.494 |
|
| 2005 |
Warnock GL, Meloche RM, Thompson D, Shapiro RJ, Fung M, Ao Z, Ho S, He Z, Dai LJ, Young L, Blackburn L, Kozak S, Kim PT, Al-Adra D, Johnson JD, et al. Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus. Archives of Surgery (Chicago, Ill. : 1960). 140: 735-44. PMID 16103282 DOI: 10.1001/Archsurg.140.8.735 |
0.397 |
|
| 2005 |
Luciani DS, Johnson JD. Acute effects of insulin on beta-cells from transplantable human islets. Molecular and Cellular Endocrinology. 241: 88-98. PMID 16099589 DOI: 10.1016/J.Mce.2005.06.006 |
0.793 |
|
| 2005 |
Ohsugi M, Cras-Méneur C, Zhou Y, Bernal-Mizrachi E, Johnson JD, Luciani DS, Polonsky KS, Permutt MA. Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion. The Journal of Biological Chemistry. 280: 4992-5003. PMID 15546857 DOI: 10.1074/Jbc.M411727200 |
0.82 |
|
| 2004 |
Bernal-Mizrachi E, Fatrai S, Johnson JD, Ohsugi M, Otani K, Han Z, Polonsky KS, Permutt MA. Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells. The Journal of Clinical Investigation. 114: 928-36. PMID 15467831 DOI: 10.1172/Jci20016 |
0.71 |
|
| 2004 |
Johnson JD, Han Z, Otani K, Ye H, Zhang Y, Wu H, Horikawa Y, Misler S, Bell GI, Polonsky KS. RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. The Journal of Biological Chemistry. 279: 24794-802. PMID 15044459 DOI: 10.1074/Jbc.M401216200 |
0.762 |
|
| 2004 |
Johnson JD, Kuang S, Misler S, Polonsky KS. Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 878-80. PMID 15033925 DOI: 10.1096/Fj.03-1280Fje |
0.804 |
|
| 2003 |
Johnson JD, Ahmed NT, Luciani DS, Han Z, Tran H, Fujita J, Misler S, Edlund H, Polonsky KS. Increased islet apoptosis in Pdx1+/- mice. The Journal of Clinical Investigation. 111: 1147-60. PMID 12697734 DOI: 10.1172/Jci16537 |
0.843 |
|
| 2002 |
Koster JC, Remedi MS, Flagg TP, Johnson JD, Markova KP, Marshall BA, Nichols CG. Hyperinsulinism induced by targeted suppression of beta cell KATP channels. Proceedings of the National Academy of Sciences of the United States of America. 99: 16992-7. PMID 12486236 DOI: 10.1073/Pnas.012479199 |
0.504 |
|
| 2002 |
Johnson JD, Misler S. Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 14566-71. PMID 12381785 DOI: 10.1073/Pnas.222099799 |
0.733 |
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