Eric Andrew Appel - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Biomaterials, Hydrogels, Polymers, Drug Delivery

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sen S, Dong C, D'Aquino AI, Yu AC, Appel EA. Biomimetic Non-ergodic Aging by Dynamic-to-covalent Transitions in Physical Hydrogels. Acs Applied Materials & Interfaces. PMID 38862125 DOI: 10.1021/acsami.4c03303  0.301
2024 Tang S, Pederson Z, Meany EL, Yen CW, Swansiger AK, Prell JS, Chen B, Grosskopf AK, Eckman N, Jiang G, Baillet J, Pellett JD, Appel EA. Label-Free Composition Analysis of Supramolecular Polymer-Nanoparticle Hydrogels by Reversed-Phase Liquid Chromatography Coupled with a Charged Aerosol Detector. Analytical Chemistry. PMID 38567987 DOI: 10.1021/acs.analchem.3c05747  0.367
2023 Tang S, Pederson Z, Meany EL, Yen CW, Swansiger AK, Prell JS, Chen B, Grosskopf AK, Eckman N, Jiang G, Baillet J, Pellett JD, Appel EA. Label-Free Composition Analysis of Supramolecular Polymer - Nanoparticle Hydrogels by Reversed-Phase Liquid Chromatography Coupled with a Charged Aerosol Detector. Biorxiv : the Preprint Server For Biology. PMID 37609276 DOI: 10.1101/2023.08.11.553055  0.375
2022 Grosskopf AK, Mann JL, Baillet J, Lopez Hernandez H, Autzen AAA, Yu AC, Appel EA. Extreme Extensibility in Physically Cross-Linked Nanocomposite Hydrogels Leveraging Dynamic Polymer-Nanoparticle Interactions. Macromolecules. 55: 7498-7511. PMID 36118599 DOI: 10.1021/acs.macromol.2c00649  0.382
2021 Grosskopf AK, Saouaf OA, Lopez Hernandez H, Appel EA. Gelation and yielding behavior of polymer-nanoparticle hydrogels. Journal of Polymer Science (2020). 59: 2854-2866. PMID 35875706 DOI: 10.1002/pol.20210652  0.376
2021 Maikawa CL, d'Aquino AI, Vuong ET, Su B, Zou L, Chen PC, Nguyen LT, Autzen AAA, Mann JL, Webber MJ, Appel EA. Affinity-Directed Dynamics of Host-Guest Motifs for Pharmacokinetic Modulation Supramolecular PEGylation. Biomacromolecules. PMID 34314146 DOI: 10.1021/acs.biomac.1c00648  0.583
2021 Meis CM, Grosskopf AK, Correa S, Appel EA. Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications. Journal of Visualized Experiments : Jove. PMID 33616104 DOI: 10.3791/62234  0.415
2020 Smith AAA, Gale EC, Roth GA, Maikawa CL, Correa S, Yu AC, Appel EA. Nanoparticles Presenting Potent TLR7/8 Agonists Enhance Anti-PD-L1 Immunotherapy in Cancer Treatment. Biomacromolecules. PMID 32816460 DOI: 10.1021/Acs.Biomac.0C00812  0.301
2020 Mann JL, Grosskopf AK, Smith AAA, Appel EA. Highly Branched Polydimethylacrylamide Copolymers as Functional Biomaterials. Biomacromolecules. PMID 32786733 DOI: 10.1021/Acs.Biomac.0C00539  0.391
2020 Smith AAA, Maikawa CL, Roth GA, Appel EA. Site-selective modification of proteins using cucurbit[7]uril as supramolecular protection for N-terminal aromatic amino acids. Organic & Biomolecular Chemistry. PMID 32459261 DOI: 10.1039/D0Ob01004A  0.302
2020 Maikawa CL, Smith AAA, Zou L, Roth GA, Gale EC, Stapleton LM, Baker SW, Mann JL, Yu AC, Correa S, Grosskopf AK, Liong CS, Meis CM, Chan D, Troxell M, ... ... Appel EA, et al. A co-formulation of supramolecularly stabilized insulin and pramlintide enhances mealtime glucagon suppression in diabetic pigs. Nature Biomedical Engineering. PMID 32393892 DOI: 10.1038/S41551-020-0555-4  0.525
2020 Maikawa CL, Smith AAA, Zou L, Meis CM, Mann JL, Webber MJ, Appel EA. Stable Monomeric Insulin Formulations Enabled by Supramolecular PEGylation of Insulin Analogues. Advanced Therapeutics. 3. PMID 32190729 DOI: 10.1002/adtp.201900094  0.5
2020 Steele AN, Paulsen MJ, Wang H, Stapleton LM, Lucian HJ, Eskandari A, Hironaka CE, Farry JM, Baker SW, Thakore AD, Jaatinen KJ, Tada Y, Hollander MJ, Williams KM, Seymour AJ, ... ... Appel EA, et al. Multi-phase catheter-injectable hydrogel enables dual-stage protein-engineered cytokine release to mitigate adverse left ventricular remodeling following myocardial infarction in a small animal model and a large animal model. Cytokine. 127: 154974. PMID 31978642 DOI: 10.1016/J.Cyto.2019.154974  0.301
2020 Smith AA, Autzen HE, Faust B, Mann JL, Muir BW, Howard S, Postma A, Spakowitz AJ, Cheng Y, Appel EA. Lipid Nanodiscs via Ordered Copolymers Chem. 6: 2782-2795. DOI: 10.1016/J.Chempr.2020.08.004  0.315
2019 Mann JL, Rossi RL, Smith AAA, Appel EA. Universal Scaling Behavior during Network Formation in Controlled Radical Polymerizations. Macromolecules. 52: 9456-9465. PMID 31894160 DOI: 10.1021/Acs.Macromol.9B02109  0.4
2019 Fenton OS, Tibbitt MW, Appel EA, Jhunjhunwala S, Webber MJ, Langer R. Injectable Polymer-Nanoparticle Hydrogels for Local Immune Cell Recruitment. Biomacromolecules. PMID 31682423 DOI: 10.1021/Acs.Biomac.9B01129  0.67
2019 Axpe E, Chan D, Offeddu GS, Chang Y, Merida D, Hernandez HL, Appel EA. A Multiscale Model for Solute Diffusion in Hydrogels. Macromolecules. 52: 6889-6897. PMID 31579160 DOI: 10.1021/Acs.Macromol.9B00753  0.303
2019 Stapleton LM, Steele AN, Wang H, Lopez Hernandez H, Yu AC, Paulsen MJ, Smith AAA, Roth GA, Thakore AD, Lucian HJ, Totherow KP, Baker SW, Tada Y, Farry JM, Eskandari A, ... ... Appel EA, et al. Use of a supramolecular polymeric hydrogel as an effective post-operative pericardial adhesion barrier. Nature Biomedical Engineering. 3: 611-620. PMID 31391596 DOI: 10.1038/S41551-019-0442-Z  0.343
2019 Maikawa CL, Sevit A, Lin B, Wallstrom RJ, Mann JL, Yu AC, Waymouth RM, Appel EA. Block copolymer composition drives function of self-assembled nanoparticles for delivery of small-molecule cargo. Journal of Polymer Science. Part a, Polymer Chemistry. 57: 1322-1332. PMID 31244507 DOI: 10.1002/Pola.29393  0.448
2019 Steele AN, Stapleton LM, Farry JM, Lucian HJ, Paulsen MJ, Eskandari A, Hironaka CE, Thakore AD, Wang H, Yu AC, Chan D, Appel EA, Woo YJ. A Biocompatible Therapeutic Catheter-Deliverable Hydrogel for In Situ Tissue Engineering. Advanced Healthcare Materials. e1801147. PMID 30714355 DOI: 10.1002/Adhm.201801147  0.48
2018 Lopez Hernandez H, Grosskopf AK, Stapleton LM, Agmon G, Appel EA. Non-Newtonian Polymer-Nanoparticle Hydrogels Enhance Cell Viability during Injection. Macromolecular Bioscience. e1800275. PMID 30369048 DOI: 10.1002/Mabi.201800275  0.35
2017 Mann JL, Yu AC, Agmon G, Appel EA. Supramolecular polymeric biomaterials. Biomaterials Science. PMID 29164196 DOI: 10.1039/C7Bm00780A  0.452
2017 Chan D, Ding Y, Dauskardt R, Appel EA. Engineering the Mechanical Properties of Polymer Networks with Precise Doping of Primary Defects. Acs Applied Materials & Interfaces. PMID 29135222 DOI: 10.1021/Acsami.7B14376  0.404
2017 Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Nature Communications. 8: 777. PMID 28974673 DOI: 10.1038/S41467-017-00600-W  0.479
2017 Fenton OS, Kauffman KJ, Kaczmarek JC, McClellan RL, Jhunjhunwala S, Tibbitt MW, Zeng MD, Appel EA, Dorkin JR, Mir FF, Yang JH, Oberli MA, Heartlein MW, DeRosa F, Langer R, et al. Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes. Advanced Materials (Deerfield Beach, Fla.). PMID 28681930 DOI: 10.1002/Adma.201606944  0.5
2017 Appel EA, Biedermann F, Hoogland D, Del Barrio J, Driscoll MD, Hay S, Wales DJ, Scherman OA. Decoupled Associative and Dissociative Processesin Strong yet Highly Dynamic Host-Guest Complexes. Journal of the American Chemical Society. PMID 28661667 DOI: 10.1021/Jacs.7B04821  0.562
2017 Yesilyurt V, Ayoob AM, Appel EA, Borenstein JT, Langer R, Anderson DG. Mixed Reversible Covalent Crosslink Kinetics Enable Precise, Hierarchical Mechanical Tuning of Hydrogel Networks. Advanced Materials (Deerfield Beach, Fla.). PMID 28295624 DOI: 10.1002/Adma.201605947  0.563
2017 Chan D, Yu AC, Appel EA. Single-Chain Polymeric Nanocarriers: A platform for determining structure-function correlations in the delivery of molecular cargo. Biomacromolecules. PMID 28263572 DOI: 10.1021/Acs.Biomac.7B00249  0.421
2017 Tan CSY, Agmon G, Liu J, Hoogland D, Janeček E, Appel EA, Scherman OA. Distinguishing relaxation dynamics in transiently crosslinked polymeric networks Polymer Chemistry. 8: 5336-5343. DOI: 10.1039/C7Py00574A  0.613
2016 Yu AC, Chen H, Chan D, Agmon G, Stapleton LM, Sevit AM, Tibbitt MW, Acosta JD, Zhang T, Franzia PW, Langer R, Appel EA. Scalable manufacturing of biomimetic moldable hydrogels for industrial applications. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911849 DOI: 10.1073/Pnas.1618156113  0.515
2016 Webber MJ, Appel EA, Vinciguerra B, Cortinas AB, Thapa LS, Jhunjhunwala S, Isaacs L, Langer R, Anderson DG. Supramolecular PEGylation of biopharmaceuticals. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911829 DOI: 10.1073/Pnas.1616639113  0.687
2016 Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang B, Yang XW, Weir G, Langer R, Anderson DG. Injectable and glucose-responsive hydrogels based on boronic acid-glucose complexation. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27455412 DOI: 10.1021/Acs.Langmuir.5B04755  0.757
2016 Fenton OS, Kauffman KJ, McClellan RL, Appel EA, Dorkin JR, Tibbitt MW, Heartlein MW, DeRosa F, Langer R, Anderson DG. Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery. Advanced Materials (Deerfield Beach, Fla.). PMID 26889757 DOI: 10.1002/Adma.201505822  0.516
2015 Appel EA, Tibbitt MW, Greer JM, Fenton OS, Kreuels K, Anderson DG, Langer R. Exploiting Electrostatic Interactions in Polymer-Nanoparticle Hydrogels. Acs Macro Letters. 4: 848-852. PMID 35596508 DOI: 10.1021/acsmacrolett.5b00416  0.614
2015 Williams PE, Jones ST, Walsh Z, Appel EA, Abo-Hamed EK, Scherman OA. Synthesis of Conducting Polymer-Metal Nanoparticle Hybrids Exploiting RAFT Polymerization. Acs Macro Letters. 4: 255-259. PMID 35596418 DOI: 10.1021/mz500645c  0.72
2015 Webber MJ, Appel EA, Meijer EW, Langer R. Supramolecular biomaterials. Nature Materials. 15: 13-26. PMID 26681596 DOI: 10.1038/nmat4474  0.674
2015 Yesilyurt V, Webber MJ, Appel EA, Godwin C, Langer R, Anderson DG. Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties. Advanced Materials (Deerfield Beach, Fla.). PMID 26540021 DOI: 10.1002/Adma.201502902  0.701
2015 Xu X, Appel EA, Liu X, Parker RM, Scherman OA, Abell C. Formation of Cucurbit[8]uril-Based Supramolecular Hydrogel Beads Using Droplet-Based Microfluidics. Biomacromolecules. 16: 2743-9. PMID 26256409 DOI: 10.1021/Acs.Biomac.5B01048  0.606
2015 Appel EA, Tibbitt MW, Webber MJ, Mattix BA, Veiseh O, Langer R. Self-assembled hydrogels utilizing polymer-nanoparticle interactions. Nature Communications. 6: 6295. PMID 25695516 DOI: 10.1038/Ncomms7295  0.77
2015 Appel EA, Larson BL, Luly KM, Kim JD, Langer R. Non-cell-adhesive substrates for printing of arrayed biomaterials. Advanced Healthcare Materials. 4: 501-5. PMID 25430948 DOI: 10.1002/Adhm.201400594  0.487
2015 Appel EA, Tibbitt MW, Webber MJ, Mattix BA, Veiseh O, Langer R. Self-assembled hydrogels utilizing polymer-nanoparticle interactions Nature Communications. 6. DOI: 10.1038/ncomms7295  0.759
2015 Williams PE, Jones ST, Walsh Z, Appel EA, Abo-Hamed EK, Scherman OA. Synthesis of conducting polymer-metal nanoparticle hybrids exploiting RAFT polymerization Acs Macro Letters. 4: 255-259. DOI: 10.1021/Mz500645C  0.74
2015 Appel EA, Tibbitt MW, Greer JM, Fenton OS, Kreuels K, Anderson DG, Langer R. Exploiting Electrostatic Interactions in Polymer-Nanoparticle Hydrogels Acs Macro Letters. 4: 848-852. DOI: 10.1021/Acsmacrolett.5B00416  0.636
2015 Miller RD, Yusoff RM, Swope WC, Rice JE, Carr AC, Parker AJ, Sly J, Appel EA, Nguyen T, Piunova V. Water soluble, biodegradable amphiphilic polymeric nanoparticles and the molecular environment of hydrophobic encapsulates: Consistency between simulation and experiment Polymer (United Kingdom). 79: 255-261. DOI: 10.1016/J.Polymer.2015.10.008  0.378
2015 Williams PE, Appel EA, Jones ST, Barrio JD, Lan Y, Scherman OA. A facile method for the stain-free visualization of hierarchical structures with electron microscopy Journal of Polymer Science, Part a: Polymer Chemistry. 53: 842-845. DOI: 10.1002/Pola.27517  0.713
2014 Appel EA, Forster RA, Rowland MJ, Scherman OA. The control of cargo release from physically crosslinked hydrogels by crosslink dynamics. Biomaterials. 35: 9897-903. PMID 25239043 DOI: 10.1016/J.Biomaterials.2014.08.001  0.579
2014 Appel EA, Forster RA, Koutsioubas A, Toprakcioglu C, Scherman OA. Activation energies control the macroscopic properties of physically cross-linked materials. Angewandte Chemie (International Ed. in English). 53: 10038-43. PMID 25056596 DOI: 10.1002/Anie.201403192  0.563
2014 Appel EA, Scherman OA. Gluing gels: A nanoparticle solution. Nature Materials. 13: 231-2. PMID 24553651 DOI: 10.1038/Nmat3893  0.587
2014 McKee JR, Appel EA, Seitsonen J, Kontturi E, Scherman OA, Ikkala O. Healable, stable and stiff hydrogels: Combining conflicting properties using dynamic and selective three-component recognition with reinforcing cellulose nanorods Advanced Functional Materials. 24: 2706-2713. DOI: 10.1002/Adfm.201303699  0.651
2013 Rowland MJ, Appel EA, Coulston RJ, Scherman OA. Dynamically crosslinked materials via recognition of amino acids by cucurbit[8]uril. Journal of Materials Chemistry. B. 1: 2904-2910. PMID 32260856 DOI: 10.1039/C3Tb20180E  0.79
2013 Rowland MJ, Appel EA, Coulston RJ, Scherman OA. Dynamically crosslinked materials via recognition of amino acids by cucurbit[8]uril Journal of Materials Chemistry B. 1: 2904-2910. DOI: 10.1039/c3tb20180e  0.737
2012 Appel EA, Rowland MJ, Loh XJ, Heywood RM, Watts C, Scherman OA. Enhanced stability and activity of temozolomide in primary glioblastoma multiforme cells with cucurbit[n]uril. Chemical Communications (Cambridge, England). 48: 9843-5. PMID 22936104 DOI: 10.1039/C2Cc35131E  0.492
2012 Appel EA, del Barrio J, Loh XJ, Scherman OA. Supramolecular polymeric hydrogels. Chemical Society Reviews. 41: 6195-214. PMID 22890548 DOI: 10.1039/C2Cs35264H  0.649
2012 Appel EA, Loh XJ, Jones ST, Biedermann F, Dreiss CA, Scherman OA. Ultrahigh-water-content supramolecular hydrogels exhibiting multistimuli responsiveness. Journal of the American Chemical Society. 134: 11767-73. PMID 22758793 DOI: 10.1021/Ja3044568  0.636
2012 Appel EA, Lee VY, Nguyen TT, McNeil M, Nederberg F, Hedrick JL, Swope WC, Rice JE, Miller RD, Sly J. Toward biodegradable nanogel star polymers via organocatalytic ROP. Chemical Communications (Cambridge, England). 48: 6163-5. PMID 22590707 DOI: 10.1039/C2Cc31406A  0.431
2012 Appel EA, Loh XJ, Jones ST, Dreiss CA, Scherman OA. Sustained release of proteins from high water content supramolecular polymer hydrogels. Biomaterials. 33: 4646-52. PMID 22459194 DOI: 10.1016/J.Biomaterials.2012.02.030  0.606
2012 Appel EA, Dyson J, del Barrio J, Walsh Z, Scherman OA. Formation of single-chain polymer nanoparticles in water through host-guest interactions. Angewandte Chemie (International Ed. in English). 51: 4185-9. PMID 22422662 DOI: 10.1002/Anie.201108659  0.744
2012 Loh XJ, del Barrio J, Toh PP, Lee TC, Jiao D, Rauwald U, Appel EA, Scherman OA. Triply triggered doxorubicin release from supramolecular nanocontainers. Biomacromolecules. 13: 84-91. PMID 22148638 DOI: 10.1021/Bm201588M  0.773
2012 Appel EA, Barrio JD, Dyson J, Isaacs L, Scherman OA. Metastable single-chain polymer nanoparticles prepared by dynamic cross-linking with nor-seco-cucurbit[10]uril Chemical Science. 3: 2278-2281. DOI: 10.1039/C2Sc20285A  0.728
2012 Loh XJ, Tsai MH, Barrio JD, Appel EA, Lee TC, Scherman OA. Triggered insulin release studies of triply responsive supramolecular micelles Polymer Chemistry. 3: 3180-3188. DOI: 10.1039/C2Py20380D  0.687
2012 Appel EA, Rauwald U, Scherman OA. Dynamic Supramolecular Polymers Polymer Science: a Comprehensive Reference, 10 Volume Set. 6: 587-628. DOI: 10.1016/B978-0-444-53349-4.00174-6  0.768
2012 Appel EA, Del Barrio J, Loh XJ, Dyson J, Scherman OA. High molecular weight polyacrylamides by atom transfer radical polymerization: Enabling advancements in water-based applications Journal of Polymer Science, Part a: Polymer Chemistry. 50: 181-186. DOI: 10.1002/Pola.25041  0.596
2011 Coulston RJ, Jones ST, Lee TC, Appel EA, Scherman OA. Supramolecular gold nanoparticle-polymer composites formed in water with cucurbit[8]uril. Chemical Communications (Cambridge, England). 47: 164-6. PMID 20842297 DOI: 10.1039/C0Cc03250F  0.779
2011 Biedermann F, Appel EA, Del Barrio J, Gruendling T, Barner-Kowollik C, Scherman OA. Postpolymerization modification of hydroxyl-functionalized polymers with isocyanates Macromolecules. 44: 4828-4835. DOI: 10.1021/Ma2008018  0.583
2010 Appel EA, Biedermann F, Rauwald U, Jones ST, Zayed JM, Scherman OA. Supramolecular cross-linked networks via host-guest complexation with cucurbit[8]uril. Journal of the American Chemical Society. 132: 14251-60. PMID 20845973 DOI: 10.1021/Ja106362W  0.785
2010 Scherman O, Appel E, Biedermann F, Rauwald U, Jones S, Zayed J. Hosting Hydrogel Formation Synfacts. 2010: 1365-1365. DOI: 10.1055/S-0030-1258938  0.742
2009 Nederberg F, Appel E, Tan JP, Kim SH, Fukushima K, Sly J, Miller RD, Waymouth RM, Yang YY, Hedrick JL. Simple approach to stabilized micelles employing miktoarm terpolymers and stereocomplexes with application in paclitaxel delivery. Biomacromolecules. 10: 1460-8. PMID 19385659 DOI: 10.1021/Bm900056G  0.411
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