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Nicholas V. Hud, Ph.D. - Publications

Affiliations: 
Chemistry Georgia Institute of Technology, Atlanta, GA 
Area:
Biophysical Chemistry
Website:
http://www.chemistry.gatech.edu/people/Hud/Nicholas

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Roche TP, Nedumpurath PJ, Karunakaran SC, Schuster GB, Hud NV. One-Pot Formation of Pairing Proto-RNA Nucleotides and Their Supramolecular Assemblies. Life (Basel, Switzerland). 13. PMID 38004340 DOI: 10.3390/life13112200  0.558
2022 Schuster GB, Hud NV, Alenaizan A. Structural and Thermodynamic Control of Supramolecular Polymers and DNA Assemblies with Cyanuric Acid: Influence of Substituents and Intermolecular Interactions. The Journal of Physical Chemistry. B. 126: 10758-10767. PMID 36502412 DOI: 10.1021/acs.jpcb.2c05934  0.501
2022 Roche TP, Fialho DM, Menor-Salvan C, Krishnamurthy R, Schuster GB, Hud NV. A Plausible Prebiotic Path to Nucleosides: Ribosides and Related Aldosides are Generated from Ribulose, Fructose, and Similar Abiotic Precursors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36261321 DOI: 10.1002/chem.202203036  0.804
2022 C M, Frenkel-Pinter M, Smith KH, Rivera-Santana VF, Sargon AB, Jacobson KC, Guzman-Martinez A, Williams LD, Leman LJ, Liotta CL, Grover MA, Hud NV. Water-Based Dynamic Depsipeptide Chemistry: Building Block Recycling and Oligomer Distribution Control Using Hydration-Dehydration Cycles. Jacs Au. 2: 1395-1404. PMID 35783166 DOI: 10.1021/jacsau.2c00087  0.795
2022 Menor-Salván C, Burcar BT, Bouza M, Fialho DM, Fernández FM, Hud NV. A Shared Prebiotic Formation of Neopterins and Guanine Nucleosides from Pyrimidine Bases. Chemistry (Weinheim An Der Bergstrasse, Germany). e202201680. PMID 35750645 DOI: 10.1002/chem.202201680  0.775
2022 Frenkel-Pinter M, Bouza M, Fernández FM, Leman LJ, Williams LD, Hud NV, Guzman-Martinez A. Thioesters provide a plausible prebiotic path to proto-peptides. Nature Communications. 13: 2569. PMID 35562173 DOI: 10.1038/s41467-022-30191-0  0.784
2022 Menor-Salvan C, Burcar B, Bouza M, Fialho D, Fernandez F, Hud NV. A shared prebiotic formation of neopterins and guanine nucleosides from pyrimidine bases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35537135 DOI: 10.1002/chem.202200714  0.803
2022 Frenkel-Pinter M, Jacobson KC, Eskew-Martin J, Forsythe JG, Grover MA, Williams LD, Hud NV. Differential Oligomerization of Alpha versus Beta Amino Acids and Hydroxy Acids in Abiotic Proto-Peptide Synthesis Reactions. Life (Basel, Switzerland). 12. PMID 35207553 DOI: 10.3390/life12020265  0.788
2022 Lozoya-Colinas A, Clifton BE, Grover MA, Hud NV. Urea and Acetamide Rich Solutions Circumvent the Strand Inhibition Problem to Allow Multiple Rounds of DNA and RNA Copying. Chembiochem : a European Journal of Chemical Biology. 23: e202100495. PMID 34797020 DOI: 10.1002/cbic.202100495  0.824
2021 Frenkel-Pinter M, Sargon AB, Glass JB, Hud NV, Williams LD. Transition metals enhance prebiotic depsipeptide oligomerization reactions involving histidine. Rsc Advances. 11: 3534-3538. PMID 35424306 DOI: 10.1039/d0ra07965k  0.769
2021 Mangalath S, Karunakaran SC, Newnam G, Schuster GB, Hud NV. Supramolecular assembly-enabled homochiral polymerization of short (dA) oligonucleotides. Chemical Communications (Cambridge, England). 57: 13602-13605. PMID 34852364 DOI: 10.1039/d1cc05420a  0.793
2021 Fialho DM, Karunakaran SC, Greeson KW, Martínez I, Schuster GB, Krishnamurthy R, Hud NV. Depsipeptide Nucleic Acids: Prebiotic Formation, Oligomerization, and Self-Assembly of a New Proto-Nucleic Acid Candidate. Journal of the American Chemical Society. PMID 34398608 DOI: 10.1021/jacs.1c02287  0.555
2021 Schuster GB, Cafferty BJ, Karunakaran SC, Hud NV. Water-Soluble Supramolecular Polymers of Paired and Stacked Heterocycles: Assembly, Structure, Properties, and a Possible Path to Pre-RNA. Journal of the American Chemical Society. PMID 34152760 DOI: 10.1021/jacs.0c13081  0.796
2021 Sahajpal NS, Mondal AK, Ananth S, Njau A, Ahluwalia P, Newnam G, Lozoya-Colinas A, Hud NV, Kota V, Ross TM, Reid MD, Fulzele S, Chaubey A, Hegde M, Rojiani AM, et al. SalivaSTAT: Direct-PCR and Pooling of Saliva Samples Collected in Healthcare and Community Setting for SARS-CoV-2 Mass Surveillance. Diagnostics (Basel, Switzerland). 11. PMID 34069462 DOI: 10.3390/diagnostics11050904  0.762
2021 Alenaizan A, Borca CH, Karunakaran SC, Kendall AK, Stubbs G, Schuster GB, Sherrill CD, Hud NV. X-ray Fiber Diffraction and Computational Analyses of Stacked Hexads in Supramolecular Polymers: Insight into Self-Assembly in Water by Prospective Prebiotic Nucleobases. Journal of the American Chemical Society. PMID 33852800 DOI: 10.1021/jacs.0c12010  0.5
2021 Frenkel-Pinter M, Rajaei V, Glass JB, Hud NV, Williams LD. Water and Life: The Medium is the Message. Journal of Molecular Evolution. PMID 33427903 DOI: 10.1007/s00239-020-09978-6  0.783
2020 Alenaizan A, Barnett JL, Hud NV, Sherrill CD, Petrov AS. The proto-Nucleic Acid Builder: a software tool for constructing nucleic acid analogs. Nucleic Acids Research. PMID 33300028 DOI: 10.1093/nar/gkaa1159  0.339
2020 Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, ... ... Hud NV, et al. A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits. The Journal of Biological Chemistry. PMID 32883809 DOI: 10.1074/Jbc.Ra120.015434  0.768
2020 Menor-Salvan C, Bouza M, Fialho DM, Burcar BT, Fernández FM, Hud NV. Prebiotic origin of pre-RNA building blocks in a urea "warm little pond" scenario. Chembiochem : a European Journal of Chemical Biology. PMID 32770593 DOI: 10.1002/Cbic.202000510  0.82
2020 Mascuch SJ, Fakhretaha-Aval S, Bowman JC, Ma MTH, Thomas G, Bommarius B, Ito C, Zhao L, Newnam GP, Matange KR, Thapa HR, Barlow B, Donegan RK, Nguyen NA, Saccuzzo EG, ... ... Hud NV, et al. Buzz about RT-qPCR: An RT-qPCR formulation for SARS-CoV-2 detection using reagents produced at Georgia Institute of Technology. Medrxiv : the Preprint Server For Health Sciences. PMID 32766604 DOI: 10.1101/2020.07.29.20163949  0.768
2020 Obianyor C, Newnam G, Clifton B, Grover M, Hud NV. Comparison of multiple factors that impact the efficiency of non-enzymatic DNA ligation: Key parameters for maximizing ligation rates and yields with carbodiimide activation. Chembiochem : a European Journal of Chemical Biology. PMID 32705742 DOI: 10.1002/Cbic.202000335  0.801
2020 Frenkel-Pinter M, Haynes JW, Mohyeldin AM, C M, Sargon AB, Petrov AS, Krishnamurthy R, Hud NV, Williams LD, Leman LJ. Mutually stabilizing interactions between proto-peptides and RNA. Nature Communications. 11: 3137. PMID 32561731 DOI: 10.1038/S41467-020-16891-5  0.812
2020 Fialho DM, Roche TP, Hud NV. Prebiotic Syntheses of Noncanonical Nucleosides and Nucleotides. Chemical Reviews. PMID 32421316 DOI: 10.1021/Acs.Chemrev.0C00069  0.808
2020 Lago JL, Burcar BT, Hud NV, Febrian R, Mehta C, Bracher PJ, Atlas ZD, Pasek MA. The Prebiotic Provenance of Semi-Aqueous Solvents. Origins of Life and Evolution of the Biosphere : the Journal of the International Society For the Study of the Origin of Life. PMID 32388697 DOI: 10.1007/S11084-020-09595-9  0.795
2020 Karunakaran SC, Cafferty BJ, Jain KS, Schuster GB, Hud NV. Reversible Transformation of a Supramolecular Hydrogel by Redox Switching of Methylene Blue-A Noncovalent Chain Stopper. Acs Omega. 5: 344-349. PMID 31956781 DOI: 10.1021/acsomega.9b02785  0.76
2019 Hud NV, Fialho DM. RNA nucleosides built in one prebiotic pot. Science (New York, N.Y.). 366: 32-33. PMID 31604291 DOI: 10.1126/Science.Aaz1130  0.355
2019 Burcar B, Castañeda A, Lago J, Daniels M, Pasek M, Hud N, Orlando T, Menor-Salvan C. A Stark contrast to modern Earth: Phosphate mineral transformation and nucleoside phosphorylation in an iron and cyanide-rich Early Earth scenario. Angewandte Chemie (International Ed. in English). PMID 31460687 DOI: 10.1002/Anie.201908272  0.775
2019 Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, Hud NV, Leman LJ, Williams LD. Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31358633 DOI: 10.1073/Pnas.1904849116  0.795
2019 He C, Lozoya-Colinas A, Gállego I, Grover MA, Hud NV. Solvent viscosity facilitates replication and ribozyme catalysis from an RNA duplex in a model prebiotic process. Nucleic Acids Research. PMID 31170298 DOI: 10.1093/Nar/Gkz496  0.802
2019 Karunakaran SC, Cafferty BJ, Weigert-Muñoz A, Schuster GB, Hud NV. Spontaneous Symmetry Breaking in the Formation of Supramolecular Polymers: Implications for the Origin of Biological Homochirality. Angewandte Chemie (International Ed. in English). 58: 1453-1457. PMID 30537392 DOI: 10.1002/Anie.201812808  0.786
2018 Hud NV. Searching for lost nucleotides of the pre-RNA World with a self-refining model of early Earth. Nature Communications. 9: 5171. PMID 30538227 DOI: 10.1038/S41467-018-07389-2  0.374
2018 Runnels CM, Lanier KA, Williams JK, Bowman JC, Petrov AS, Hud NV, Williams LD. Folding, Assembly, and Persistence: The Essential Nature and Origins of Biopolymers. Journal of Molecular Evolution. PMID 30456440 DOI: 10.1007/S00239-018-9876-2  0.692
2018 Bray MS, Lenz TK, Haynes JW, Bowman JC, Petrov AS, Reddi AR, Hud NV, Williams LD, Glass JB. Multiple prebiotic metals mediate translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30413624 DOI: 10.1073/Pnas.1803636115  0.636
2018 McKee AD, Orlando TM, Hud NV, Bennett C, Saydjari AK, Solano M. A possible path to prebiotic peptides involving silica and hydroxy acid-mediated amide bond formation. Chembiochem : a European Journal of Chemical Biology. PMID 29959812 DOI: 10.1002/Cbic.201800217  0.347
2018 Fialho DM, Clarke KC, Moore MK, Schuster GB, Krishnamurthy R, Hud NV. Glycosylation of a model proto-RNA nucleobase with non-ribose sugars: implications for the prebiotic synthesis of nucleosides. Organic & Biomolecular Chemistry. PMID 29308815 DOI: 10.1039/C7Ob03017G  0.585
2018 Karunakaran SC, Cafferty BJ, Peláez-Fernández M, Neselu K, Schmidt-Krey I, Fernandez-Nieves A, Schuster GB, Hud NV. Exquisite regulation of supramolecular equilibrium polymers in water: chain stoppers control length, polydispersity and viscoelasticity Polymer Chemistry. 9: 5268-5277. DOI: 10.1039/C8Py01146J  0.766
2017 Gull M, Cafferty BJ, Hud NV, Pasek MA. Silicate-Promoted Phosphorylation of Glycerol in Non-Aqueous Solvents: A Prebiotically Plausible Route to Organophosphates. Life (Basel, Switzerland). 7. PMID 28661422 DOI: 10.3390/Life7030029  0.726
2017 He C, Gállego I, Laughlin B, Grover MA, Hud NV. A viscous solvent enables information transfer from gene-length nucleic acids in a model prebiotic replication cycle. Nature Chemistry. 9: 318-324. PMID 28338690 DOI: 10.1038/Nchem.2628  0.821
2017 Okafor CD, Lanier KA, Petrov AS, Athavale SS, Bowman JC, Hud NV, Williams LD. Iron mediates catalysis of nucleic acid processing enzymes: support for Fe(II) as a cofactor before the great oxidation event. Nucleic Acids Research. PMID 28334877 DOI: 10.1093/Nar/Gkx171  0.755
2017 Lenz TK, Norris AM, Hud NV, Williams LD. Protein-free ribosomal RNA folds to a near-native state in the presence of Mg2+ Rsc Advances. 7: 54674-54681. DOI: 10.1039/C7Ra08696B  0.674
2017 Yu S, Solano MD, Blanchard MK, Soper-Hopper MT, Krishnamurthy R, Fernández FM, Hud NV, Schork FJ, Grover MA. Elongation of Model Prebiotic Proto-Peptides by Continuous Monomer Feeding Macromolecules. 50: 9286-9294. DOI: 10.1021/Acs.Macromol.7B01569  0.349
2016 Yu SS, Krishnamurthy R, Fernández FM, Hud NV, Schork FJ, Grover MA. Kinetics of prebiotic depsipeptide formation from the ester-amide exchange reaction. Physical Chemistry Chemical Physics : Pccp. PMID 27711571 DOI: 10.1039/C6Cp05527C  0.344
2016 Gavette JV, Stoop M, Hud NV, Krishnamurthy R. RNA-DNA Chimeras in the Context of an RNA World Transition to an RNA/DNA World. Angewandte Chemie (International Ed. in English). PMID 27650222 DOI: 10.1002/Anie.201607919  0.431
2016 Burcar B, Pasek M, Gull M, Cafferty BJ, Velasco F, Hud NV, Menor-Salván C. Darwin's Warm Little Pond: A One-Pot Reaction for Prebiotic Phosphorylation and the Mobilization of Phosphate from Minerals in a Urea-based Solvent. Angewandte Chemie (International Ed. in English). PMID 27532228 DOI: 10.1002/Anie.201606239  0.791
2016 Li C, Cafferty BJ, Karunakaran SC, Schuster GB, Hud NV. Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: implications for the possible origins of RNA. Physical Chemistry Chemical Physics : Pccp. PMID 27253677 DOI: 10.1039/C6Cp03047E  0.794
2016 Cafferty BJ, Fialho DM, Khanam J, Krishnamurthy R, Hud NV. Spontaneous formation and base pairing of plausible prebiotic nucleotides in water. Nature Communications. 7: 11328. PMID 27108699 DOI: 10.1038/Ncomms11328  0.777
2016 Cafferty BJ, Musetti C, Kim K, Horowitz ED, Krishnamurthy R, Hud NV. Small molecule-mediated duplex formation of nucleic acids with 'incompatible' backbones. Chemical Communications (Cambridge, England). PMID 27009481 DOI: 10.1039/C6Cc00779A  0.818
2016 Gulen B, Petrov AS, Okafor CD, Vander Wood D, O'Neill EB, Hud NV, Williams LD. Ribosomal small subunit domains radiate from a central core. Scientific Reports. 6: 20885. PMID 26876483 DOI: 10.1038/Srep20885  0.735
2016 Hud N. Our Odyssey to Find a Plausible Prebiotic Path to RNA: The First Twenty Years Synlett. 28: 36-55. DOI: 10.1055/S-0036-1588646  0.429
2016 Burcar B, Pasek M, Gull M, Cafferty BJ, Velasco F, Hud NV, Menor-Salván C. Cover Picture: Darwin's Warm Little Pond: A One-Pot Reaction for Prebiotic Phosphorylation and the Mobilization of Phosphate from Minerals in a Urea-Based Solvent (Angew. Chem. Int. Ed. 42/2016) Angewandte Chemie International Edition. 55: 12915-12915. DOI: 10.1002/Anie.201607773  0.715
2015 Petrov AS, Gulen B, Norris AM, Kovacs NA, Bernier CR, Lanier KA, Fox GE, Harvey SC, Wartell RM, Hud NV, Williams LD. History of the ribosome and the origin of translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621738 DOI: 10.1073/Pnas.1509761112  0.663
2015 Forsythe JG, Yu SS, Mamajanov I, Grover MA, Krishnamurthy R, Fernández FM, Hud NV. Ester-Mediated Amide Bond Formation Driven by Wet-Dry Cycles: A Possible Path to Polypeptides on the Prebiotic Earth. Angewandte Chemie (International Ed. in English). PMID 26201989 DOI: 10.1002/Anie.201503792  0.728
2015 Forsythe JG, Yu SS, Mamajanov I, Grover MA, Krishnamurthy R, Fernández FM, Hud NV. Ester-Mediated Amide Bond Formation Driven by Wet-Dry Cycles: A Possible Path to Polypeptides on the Prebiotic Earth. Angewandte Chemie (International Ed. in English). PMID 26201989 DOI: 10.1002/Anie.201503792  0.728
2015 Gállego I, Grover MA, Hud NV. Folding and imaging of DNA nanostructures in anhydrous and hydrated deep-eutectic solvents. Angewandte Chemie (International Ed. in English). 54: 6765-9. PMID 25900011 DOI: 10.1002/Anie.201412354  0.789
2015 Bowman JC, Hud NV, Williams LD. The ribosome challenge to the RNA world. Journal of Molecular Evolution. 80: 143-61. PMID 25739364 DOI: 10.1007/S00239-015-9669-9  0.701
2015 Cafferty BJ, Hud NV. Was a Pyrimidine-Pyrimidine Base Pair the Ancestor of Watson-Crick Base Pairs? Insights from a Systematic Approach to the Origin of RNA Israel Journal of Chemistry. DOI: 10.1002/Ijch.201400206  0.766
2015 Gállego I, Grover MA, Hud NV. Cover Picture: Folding and Imaging of DNA Nanostructures in Anhydrous and Hydrated Deep-Eutectic Solvents (Angew. Chem. Int. Ed. 23/2015) Angewandte Chemie International Edition. 54: 6653-6653. DOI: 10.1002/Anie.201503959  0.767
2015 Gállego I, Grover MA, Hud NV. Titelbild: Folding and Imaging of DNA Nanostructures in Anhydrous and Hydrated Deep-Eutectic Solvents (Angew. Chem. 23/2015) Angewandte Chemie. 127: 6753-6753. DOI: 10.1002/Ange.201503959  0.767
2014 Cafferty BJ, Hud NV. Abiotic synthesis of RNA in water: a common goal of prebiotic chemistry and bottom-up synthetic biology. Current Opinion in Chemical Biology. 22: 146-57. PMID 25438801 DOI: 10.1016/J.Cbpa.2014.09.015  0.762
2014 Petrov AS, Bernier CR, Hsiao C, Norris AM, Kovacs NA, Waterbury CC, Stepanov VG, Harvey SC, Fox GE, Wartell RM, Hud NV, Williams LD. Evolution of the ribosome at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 111: 10251-6. PMID 24982194 DOI: 10.1073/Pnas.1407205111  0.673
2014 Petrov AS, Bernier CR, Gulen B, Waterbury CC, Hershkovits E, Hsiao C, Harvey SC, Hud NV, Fox GE, Wartell RM, Williams LD. Secondary structures of rRNAs from all three domains of life. Plos One. 9: e88222. PMID 24505437 DOI: 10.1371/Journal.Pone.0088222  0.665
2014 Portella G, Germann MW, Hud NV, Orozco M. MD and NMR analyses of choline and TMA binding to duplex DNA: on the origins of aberrant sequence-dependent stability by alkyl cations in aqueous and water-free solvents. Journal of the American Chemical Society. 136: 3075-86. PMID 24490755 DOI: 10.1021/Ja410698U  0.376
2014 Chen MC, Cafferty BJ, Mamajanov I, Gállego I, Khanam J, Krishnamurthy R, Hud NV. Spontaneous prebiotic formation of a β-ribofuranoside that self-assembles with a complementary heterocycle. Journal of the American Chemical Society. 136: 5640-6. PMID 24328232 DOI: 10.1021/Ja410124V  0.818
2014 Cafferty BJ, Avirah RR, Schuster GB, Hud NV. Ultra-sensitive pH control of supramolecular polymers and hydrogels: PKa matching of biomimetic monomers Chemical Science. 5: 4681-4686. DOI: 10.1039/C4Sc02182G  0.758
2014 Cafferty BJ, Avirah RR, Schuster GB, Hud NV. Ultra-sensitive pH control of supramolecular polymers and hydrogels: PKa matching of biomimetic monomers Chemical Science. 5: 4681-4686. DOI: 10.1039/C4Sc02182G  0.758
2014 Mamajanov I, Macdonald PJ, Ying J, Duncanson DM, Dowdy GR, Walker CA, Engelhart AE, Fernández FM, Grover MA, Hud NV, Schork FJ. Ester formation and hydrolysis during wet-dry cycles: Generation of far-from-equilibrium polymers in a model prebiotic reaction Macromolecules. 47: 1334-1343. DOI: 10.1021/Ma402256D  0.802
2014 Mamajanov I, Macdonald PJ, Ying J, Duncanson DM, Dowdy GR, Walker CA, Engelhart AE, Fernández FM, Grover MA, Hud NV, Schork FJ. Ester formation and hydrolysis during wet-dry cycles: Generation of far-from-equilibrium polymers in a model prebiotic reaction Macromolecules. 47: 1334-1343. DOI: 10.1021/Ma402256D  0.802
2014 He C, Gállego I, Laughlin B, Hud N, Grover M. The effects of viscosity on nucleic acid assembly: A possible solution to the strand inhibition problem Engineering Sciences and Fundamentals 2014 - Core Programming Area At the 2014 Aiche Annual Meeting. 2: 1162.  0.754
2013 Petrov AS, Bernier CR, Hershkovits E, Xue Y, Waterbury CC, Hsiao C, Stepanov VG, Gaucher EA, Grover MA, Harvey SC, Hud NV, Wartell RM, Fox GE, Williams LD. Secondary structure and domain architecture of the 23S and 5S rRNAs. Nucleic Acids Research. 41: 7522-35. PMID 23771137 DOI: 10.1093/Nar/Gkt513  0.646
2013 Hsiao C, Chou IC, Okafor CD, Bowman JC, O'Neill EB, Athavale SS, Petrov AS, Hud NV, Wartell RM, Harvey SC, Williams LD. RNA with iron(II) as a cofactor catalyses electron transfer. Nature Chemistry. 5: 525-8. PMID 23695635 DOI: 10.1038/Nchem.1649  0.76
2013 Hud NV, Cafferty BJ, Krishnamurthy R, Williams LD. The origin of RNA and "my grandfather's axe". Chemistry & Biology. 20: 466-74. PMID 23601635 DOI: 10.1016/J.Chembiol.2013.03.012  0.811
2013 Cafferty BJ, Gállego I, Chen MC, Farley KI, Eritja R, Hud NV. Efficient self-assembly in water of long noncovalent polymers by nucleobase analogues. Journal of the American Chemical Society. 135: 2447-50. PMID 23394182 DOI: 10.1021/Ja312155V  0.801
2013 Hsiao C, Lenz TK, Peters JK, Fang PY, Schneider DM, Anderson EJ, Preeprem T, Bowman JC, O'Neill EB, Lie L, Athavale SS, Gossett JJ, Trippe C, Murray J, Petrov AS, ... ... Hud NV, et al. Molecular paleontology: a biochemical model of the ancestral ribosome. Nucleic Acids Research. 41: 3373-85. PMID 23355613 DOI: 10.1093/Nar/Gkt023  0.675
2013 Athavale SS, Gossett JJ, Bowman JC, Hud NV, Williams LD, Harvey SC. In vitro secondary structure of the genomic RNA of satellite tobacco mosaic virus. Plos One. 8: e54384. PMID 23349871 DOI: 10.1371/Journal.Pone.0054384  0.698
2013 Parker TM, Hohenstein EG, Parrish RM, Hud NV, Sherrill CD. Quantum-mechanical analysis of the energetic contributions to Ï€ stacking in nucleic acids versus rise, twist, and slide. Journal of the American Chemical Society. 135: 1306-16. PMID 23265256 DOI: 10.1021/Ja3063309  0.408
2013 Kuruvilla E, Schuster GB, Hud NV. Enhanced nonenzymatic ligation of homopurine miniduplexes: support for greater base stacking in a pre-RNA world. Chembiochem : a European Journal of Chemical Biology. 14: 45-8. PMID 23225671 DOI: 10.1002/Cbic.201200601  0.585
2013 Mamajanov I, Lannan FM, Hud NV. 49 Nucleic acids in anhydrous media: G-quadruplex folding governed by Kramers rate theory Journal of Biomolecular Structure and Dynamics. 31: 29-30. DOI: 10.1080/07391102.2013.786483  0.735
2013 Gállego I, Cafferty BJ, Chen MC, Farley KI, Eritja R, Hud NV. 20 Supramolecular polymerization of nucleobase-like monomers in water Journal of Biomolecular Structure and Dynamics. 31: 12-12. DOI: 10.1080/07391102.2013.786442  0.801
2012 Petrov AS, Bernier CR, Hsiao C, Okafor CD, Tannenbaum E, Stern J, Gaucher E, Schneider D, Hud NV, Harvey SC, Williams LD. RNA-magnesium-protein interactions in large ribosomal subunit. The Journal of Physical Chemistry. B. 116: 8113-20. PMID 22712611 DOI: 10.1021/Jp304723W  0.763
2012 Athavale SS, Petrov AS, Hsiao C, Watkins D, Prickett CD, Gossett JJ, Lie L, Bowman JC, O'Neill E, Bernier CR, Hud NV, Wartell RM, Harvey SC, Williams LD. RNA folding and catalysis mediated by iron (II). Plos One. 7: e38024. PMID 22701543 DOI: 10.1371/Journal.Pone.0038024  0.682
2012 Lannan FM, Mamajanov I, Hud NV. Human telomere sequence DNA in water-free and high-viscosity solvents: G-quadruplex folding governed by Kramers rate theory. Journal of the American Chemical Society. 134: 15324-30. PMID 22651378 DOI: 10.1021/Ja303499M  0.763
2012 Bowman JC, Lenz TK, Hud NV, Williams LD. Cations in charge: magnesium ions in RNA folding and catalysis. Current Opinion in Structural Biology. 22: 262-72. PMID 22595008 DOI: 10.1016/J.Sbi.2012.04.006  0.668
2012 Engelhart AE, Cafferty BJ, Okafor CD, Chen MC, Williams LD, Lynn DG, Hud NV. Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR. Chembiochem : a European Journal of Chemical Biology. 13: 1121-4. PMID 22556064 DOI: 10.1002/Cbic.201200167  0.802
2012 Walker SI, Grover MA, Hud NV. Universal sequence replication, reversible polymerization and early functional biopolymers: a model for the initiation of prebiotic sequence evolution. Plos One. 7: e34166. PMID 22493682 DOI: 10.1371/Journal.Pone.0034166  0.66
2012 Athavale SS, Gossett JJ, Hsiao C, Bowman JC, O'Neill E, Hershkovitz E, Preeprem T, Hud NV, Wartell RM, Harvey SC, Williams LD. Domain III of the T. thermophilus 23S rRNA folds independently to a near-native state. Rna (New York, N.Y.). 18: 752-8. PMID 22334759 DOI: 10.1261/Rna.030692.111  0.636
2012 Maehigashi T, Hsiao C, Woods KK, Moulaei T, Hud NV, Williams LD. B-DNA structure is intrinsically polymorphic: even at the level of base pair positions. Nucleic Acids Research. 40: 3714-22. PMID 22180536 DOI: 10.1093/Nar/Gkr1168  0.695
2011 Anumukonda LN, Young A, Lynn DG, Buckley R, Warrayat A, Graves CL, Bean HD, Hud NV. Adenine Synthesis in a Model Prebiotic Reaction: Connecting Origin of Life Chemistry with Biology. Journal of Chemical Education. 88: 1698-1701. PMID 22075932 DOI: 10.1021/Ed1012074  0.77
2011 Buckley R, Enekwa CD, Williams LD, Hud NV. Molecular recognition of Watson-Crick-like purine-purine base pairs. Chembiochem : a European Journal of Chemical Biology. 12: 2155-8. PMID 21805554 DOI: 10.1002/Cbic.201100375  0.76
2010 Mamajanov I, Engelhart AE, Bean HD, Hud NV. DNA and RNA in anhydrous media: duplex, triplex, and G-quadruplex secondary structures in a deep eutectic solvent. Angewandte Chemie (International Ed. in English). 49: 6310-4. PMID 20623813 DOI: 10.1002/Anie.201001561  0.811
2010 Barks HL, Buckley R, Grieves GA, Di Mauro E, Hud NV, Orlando TM. Guanine, adenine, and hypoxanthine production in UV-irradiated formamide solutions: relaxation of the requirements for prebiotic purine nucleobase formation. Chembiochem : a European Journal of Chemical Biology. 11: 1240-3. PMID 20491139 DOI: 10.1002/Cbic.201000074  0.574
2010 Engelhart AE, Hud NV. Primitive genetic polymers. Cold Spring Harbor Perspectives in Biology. 2: a002196. PMID 20462999 DOI: 10.1101/Cshperspect.A002196  0.76
2010 Horowitz ED, Engelhart AE, Chen MC, Quarles KA, Smith MW, Lynn DG, Hud NV. Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world. Proceedings of the National Academy of Sciences of the United States of America. 107: 5288-93. PMID 20212163 DOI: 10.1073/Pnas.0914172107  0.828
2010 Barks HL, Buckley R, Grieves GA, Di Mauro E, Hud NV, Orlando TM. Cover Picture: Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation (ChemBioChem 9/2010) Chembiochem. 11: 1153-1153. DOI: 10.1002/Cbic.201090037  0.556
2009 Joung IS, Persil Cetinkol O, Hud NV, Cheatham TE. Molecular dynamics simulations and coupled nucleotide substitution experiments indicate the nature of A{middle dot}A base pairing and a putative structure of the coralyne-induced homo-adenine duplex. Nucleic Acids Research. 37: 7715-27. PMID 19850721 DOI: 10.1093/Nar/Gkp730  0.37
2009 Sheng Y, Bean HD, Mamajanov I, Hud NV, Leszczynski J. Comprehensive investigation of the energetics of pyrimidine nucleoside formation in a model prebiotic reaction. Journal of the American Chemical Society. 131: 16088-95. PMID 19839590 DOI: 10.1021/Ja900807M  0.81
2009 Hud NV. Mineral surfaces: a mixed blessing for the RNA world? Astrobiology. 9: 253-5; discussion 25. PMID 19371165 DOI: 10.1089/Ast.2008.0928  0.346
2009 Engelhart AE, Morton TH, Hud NV. Evidence of strong hydrogen bonding by 8-aminoguanine. Chemical Communications (Cambridge, England). 647-9. PMID 19322409 DOI: 10.1039/B818409G  0.689
2009 Horowitz ED, Lilavivat S, Holladay BW, Germann MW, Hud NV. Solution structure and thermodynamics of 2',5' RNA intercalation. Journal of the American Chemical Society. 131: 5831-8. PMID 19309071 DOI: 10.1021/Ja810068E  0.767
2009 Sarkar T, Petrov AS, Vitko JR, Santai CT, Harvey SC, Mukerji I, Hud NV. Integration host factor (IHF) dictates the structure of polyamine-DNA condensates: implications for the role of IHF in the compaction of bacterial chromatin. Biochemistry. 48: 667-75. PMID 19132923 DOI: 10.1021/Bi8019965  0.797
2009 Tsai AG, Engelhart AE, Hatmal MM, Houston SI, Hud NV, Haworth IS, Lieber MR. Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. The Journal of Biological Chemistry. 284: 7157-64. PMID 19106104 DOI: 10.1074/Jbc.M806866200  0.722
2009 Cetinkol OP, Hud NV. Molecular recognition of poly(A) by small ligands: an alternative method of analysis reveals nanomolar, cooperative and shape-selective binding. Nucleic Acids Research. 37: 611-21. PMID 19073699 DOI: 10.1093/Nar/Gkn977  0.797
2009 Bean HD, Lynn DG, Hud NV. Self-assembly and the origin of the first RNA-like polymers Acs Symposium Series. 1025: 109-132. DOI: 10.1021/bk-2009-1025.ch006  0.706
2009 Bean HD, Lynn DG, Hud NV. Self-assembly and the origin of the first RNA-like polymers Acs Symposium Series. 1025: 109-132. DOI: 10.1021/bk-2009-1025.ch006  0.706
2009 Petrov AS, Sarkar T, Hud NV, Harvey SC. Modeling DNA Condensation Phenomena by Coarse-Gained Models: Biophysical Journal. 96: 422a. DOI: 10.1016/J.Bpj.2008.12.2160  0.591
2008 Cetinkol OP, Engelhart AE, Nanjunda RK, Wilson WD, Hud NV. Submicromolar, selective G-quadruplex ligands from one pot: thermodynamic and structural studies of human telomeric DNA binding by azacyanines. Chembiochem : a European Journal of Chemical Biology. 9: 1889-92. PMID 18600816 DOI: 10.1002/Cbic.200800234  0.788
2007 Persil O, Hud NV. Harnessing DNA intercalation. Trends in Biotechnology. 25: 433-6. PMID 17825446 DOI: 10.1016/J.Tibtech.2007.08.003  0.393
2007 Bean HD, Sheng Y, Collins JP, Anet FA, Leszczynski J, Hud NV. Formation of a beta-pyrimidine nucleoside by a free pyrimidine base and ribose in a plausible prebiotic reaction. Journal of the American Chemical Society. 129: 9556-7. PMID 17629276 DOI: 10.1021/Ja072781A  0.802
2007 Hud NV, Jain SS, Li X, Lynn DG. Addressing the problems of base pairing and strand cyclization in template-directed synthesis: a case for the utility and necessity of 'molecular midwives' and reversible backbone linkages for the origin of proto-RNA. Chemistry & Biodiversity. 4: 768-83. PMID 17443888 DOI: 10.1002/Cbdv.200790063  0.638
2007 Sarkar T, Vitoc I, Mukerji I, Hud NV. Bacterial protein HU dictates the morphology of DNA condensates produced by crowding agents and polyamines. Nucleic Acids Research. 35: 951-61. PMID 17259223 DOI: 10.1093/Nar/Gkl1093  0.579
2006 Horowitz ED, Hud NV. Ethidium and proflavine binding to a 2',5'-linked RNA duplex. Journal of the American Chemical Society. 128: 15380-1. PMID 17131997 DOI: 10.1021/Ja065339L  0.765
2006 Vilfan ID, Conwell CC, Sarkar T, Hud NV. Time study of DNA condensate morphology: implications regarding the nucleation, growth, and equilibrium populations of toroids and rods. Biochemistry. 45: 8174-83. PMID 16800642 DOI: 10.1021/Bi060396C  0.8
2006 Bean HD, Anet FA, Gould IR, Hud NV. Glyoxylate as a backbone linkage for a prebiotic ancestor of RNA. Origins of Life and Evolution of the Biosphere : the Journal of the International Society For the Study of the Origin of Life. 36: 39-63. PMID 16372197 DOI: 10.1007/S11084-005-2082-4  0.821
2005 Hud NV, Vilfan ID. Toroidal DNA condensates: unraveling the fine structure and the role of nucleation in determining size. Annual Review of Biophysics and Biomolecular Structure. 34: 295-318. PMID 15869392 DOI: 10.1146/Annurev.Biophys.34.040204.144500  0.694
2005 Sarkar T, Conwell CC, Harvey LC, Santai CT, Hud NV. Condensation of oligonucleotides assembled into nicked and gapped duplexes: potential structures for oligonucleotide delivery. Nucleic Acids Research. 33: 143-51. PMID 15640449 DOI: 10.1093/Nar/Gki156  0.812
2004 Persil O, Santai CT, Jain SS, Hud NV. Assembly of an antiparallel homo-adenine DNA duplex by small-molecule binding. Journal of the American Chemical Society. 126: 8644-5. PMID 15250704 DOI: 10.1021/Ja0492891  0.81
2004 Conwell CC, Hud NV. Evidence that both kinetic and thermodynamic factors govern DNA toroid dimensions: effects of magnesium(II) on DNA condensation by hexammine cobalt(III). Biochemistry. 43: 5380-7. PMID 15122904 DOI: 10.1021/Bi049872U  0.78
2004 Petty JT, Zheng J, Hud NV, Dickson RM. DNA-templated Ag nanocluster formation. Journal of the American Chemical Society. 126: 5207-12. PMID 15099104 DOI: 10.1021/Ja031931O  0.327
2004 Jain SS, Anet FA, Stahle CJ, Hud NV. Enzymatic behavior by intercalating molecules in a template-directed ligation reaction. Angewandte Chemie (International Ed. in English). 43: 2004-8. PMID 15065286 DOI: 10.1002/Anie.200353155  0.78
2004 Vilfan ID, Conwell CC, Hud NV. Formation of native-like mammalian sperm cell chromatin with folded bull protamine. The Journal of Biological Chemistry. 279: 20088-95. PMID 14990583 DOI: 10.1074/Jbc.M312777200  0.797
2004 Jain SS, Anet FAL, Stahle CJ, Hud NV. Cover Picture: Enzymatic Behavior by Intercalating Molecules in a Template-Directed Ligation Reaction (Angew. Chem. Int. Ed. 15/2004) Angewandte Chemie International Edition. 43: 1895-1895. DOI: 10.1002/Anie.200490041  0.534
2004 Jain SS, Anet FAL, Stahle CJ, Hud NV. Titelbild: Enzymatic Behavior by Intercalating Molecules in a Template-Directed Ligation Reaction (Angew. Chem. 15/2004) Angewandte Chemie. 116: 1931-1931. DOI: 10.1002/Ange.200490041  0.534
2003 Jain SS, Polak M, Hud NV. Controlling nucleic acid secondary structure by intercalation: effects of DNA strand length on coralyne-driven duplex disproportionation. Nucleic Acids Research. 31: 4608-15. PMID 12888521 DOI: 10.1093/Nar/Gkg648  0.812
2003 Conwell CC, Vilfan ID, Hud NV. Controlling the size of nanoscale toroidal DNA condensates with static curvature and ionic strength. Proceedings of the National Academy of Sciences of the United States of America. 100: 9296-301. PMID 12871999 DOI: 10.1073/Pnas.1533135100  0.81
2003 Hud NV, Plavec J. A unified model for the origin of DNA sequence-directed curvature. Biopolymers. 69: 144-58. PMID 12717729 DOI: 10.1002/Bip.10364  0.363
2003 Coulberson AL, Hud NV, LeDoux JM, Vilfan ID, Prausnitz MR. Gene packaging with lipids, peptides and viruses inhibits transfection by electroporation in vitro. Journal of Controlled Release : Official Journal of the Controlled Release Society. 86: 361-70. PMID 12526831 DOI: 10.1016/S0168-3659(02)00417-0  0.639
2003 Conwell CC, Hud NV. MgCl2 Enhances Cluster Formation by Nanoscale Toroidal DNA Condensates Journal of Cluster Science. 14: 115-122. DOI: 10.1023/A:1024837520146  0.777
2002 Hud NV, Feigon J. Characterization of divalent cation localization in the minor groove of the A(n)T(n) and T(n)A(n) DNA sequence elements by (1)H NMR spectroscopy and manganese(II). Biochemistry. 41: 9900-10. PMID 12146955 DOI: 10.1021/Bi020159J  0.511
2002 Polak M, Hud NV. Complete disproportionation of duplex poly(dT)*poly(dA) into triplex poly(dT)*poly(dA)*poly(dT) and poly(dA) by coralyne. Nucleic Acids Research. 30: 983-92. PMID 11842110 DOI: 10.1093/Nar/30.4.983  0.794
2001 Hud NV, Downing KH. Cryoelectron microscopy of lambda phage DNA condensates in vitreous ice: the fine structure of DNA toroids. Proceedings of the National Academy of Sciences of the United States of America. 98: 14925-30. PMID 11734630 DOI: 10.1073/Pnas.261560398  0.35
2001 Feigon J, Butcher SE, Finger LD, Hud NV. Solution nuclear magnetic resonance probing of cation binding sites on nucleic acids. Methods in Enzymology. 338: 400-20. PMID 11460560 DOI: 10.1016/S0076-6879(02)38230-2  0.772
2001 Hud NV, Polak M. DNA-cation interactions: The major and minor grooves are flexible ionophores. Current Opinion in Structural Biology. 11: 293-301. PMID 11406377 DOI: 10.1016/S0959-440X(00)00205-0  0.356
2000 Hud NV, Anet FA. Intercalation-mediated synthesis and replication: a new approach to the origin of life. Journal of Theoretical Biology. 205: 543-62. PMID 10931751 DOI: 10.1006/Jtbi.2000.2084  0.813
2000 Rovnyak D, Baldus M, Wu G, Hud NV, Feigon J, Griffin RG. Localization of 23Na+ in a DNA quadruplex by high-field solid-state NMR Journal of the American Chemical Society. 122: 11423-11429. DOI: 10.1021/Ja001022O  0.593
2000 Rovnyak D, Baldus M, Wu G, Hud NV, Feigon J, Griffin RG. Localization of 23Na+ in a DNA quadruplex by high-field solid-state NMR Journal of the American Chemical Society. 122: 11423-11429. DOI: 10.1021/Ja001022O  0.593
2000 Shen MR, Downing KH, Balhorn R, Hud NV. Nucleation of DNA condensation by static loops: Formation of DNA toroids with reduced dimensions Journal of the American Chemical Society. 122: 4833-4834. DOI: 10.1021/Ja000200A  0.613
1999 Schultze P, Hud NV, Smith FW, Feigon J. The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4)). Nucleic Acids Research. 27: 3018-28. PMID 10454595 DOI: 10.1093/Nar/27.15.3018  0.559
1999 Hud NV, Sklenár V, Feigon J. Localization of ammonium ions in the minor groove of DNA duplexes in solution and the origin of DNA A-tract bending. Journal of Molecular Biology. 286: 651-60. PMID 10024440 DOI: 10.1006/Jmbi.1998.2513  0.601
1999 Hud NV, Schultze P, Sklenár V, Feigon J. Binding sites and dynamics of ammonium ions in a telomere repeat DNA quadruplex. Journal of Molecular Biology. 285: 233-43. PMID 9878402 DOI: 10.1006/Jmbi.1998.2327  0.587
1998 Hud NV, Schultze P, Feigon J. Ammonium ion as an NMR probe for monovalent cation coordination sites of DNA quadruplexes [2] Journal of the American Chemical Society. 120: 6403-6404. DOI: 10.1021/Ja9811039  0.561
1997 Hud NV, Feigon J. Localization of divalent metal ions in the minor groove of DNA A-tracts Journal of the American Chemical Society. 119: 5756-5757. DOI: 10.1021/Ja9704085  0.54
1997 Hud NV, Feigon J. Localization of divalent metal ions in the minor groove of DNA A-tracts Journal of the American Chemical Society. 119: 5756-5757. DOI: 10.1021/Ja9704085  0.54
1996 Hud NV, Smith FW, Anet FA, Feigon J. The selectivity for K+ versus Na+ in DNA quadruplexes is dominated by relative free energies of hydration: a thermodynamic analysis by 1H NMR. Biochemistry. 35: 15383-90. PMID 8952490 DOI: 10.1021/Bi9620565  0.779
1995 Hud NV. Double-stranded DNA organization in bacteriophage heads: an alternative toroid-based model. Biophysical Journal. 69: 1355-62. PMID 8534805 DOI: 10.1016/S0006-3495(95)80002-0  0.363
1995 Hud NV, Downing KH, Balhorn R. A constant radius of curvature model for the organization of DNA in toroidal condensates. Proceedings of the National Academy of Sciences of the United States of America. 92: 3581-5. PMID 7724602 DOI: 10.1073/Pnas.92.8.3581  0.61
1994 Hud NV, Milanovich FP, Balhorn R. Evidence of novel secondary structure in DNA-bound protamine is revealed by Raman spectroscopy. Biochemistry. 33: 7528-35. PMID 8011618 DOI: 10.1021/Bi00190A005  0.622
1993 Hud NV, Allen MJ, Downing KH, Lee J, Balhorn R. Identification of the elemental packing unit of DNA in mammalian sperm cells by atomic force microscopy. Biochemical and Biophysical Research Communications. 193: 1347-54. PMID 8323555 DOI: 10.1006/Bbrc.1993.1773  0.596
1992 Allen MJ, Hud NV, Balooch M, Tench RJ, Siekhaus WJ, Balhorn R. Tip-radius-induced artifacts in AFM images of protamine-complexed DNA fibers. Ultramicroscopy. 42: 1095-100. PMID 1413246 DOI: 10.1016/0304-3991(92)90408-C  0.557
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