| Year |
Citation |
Score |
| 2021 |
Greenwood HE, Witney TH. Latest advances in imaging oxidative stress in cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 34353871 DOI: 10.2967/jnumed.120.256974 |
0.685 |
|
| 2021 |
Edwards R, Greenwood HE, McRobbie G, Khan I, Witney TH. Robust and Facile Automated Radiosynthesis of [F]FSPG on the GE FASTlab. Molecular Imaging and Biology. PMID 34013395 DOI: 10.1007/s11307-021-01609-w |
0.77 |
|
| 2020 |
Witney TH, Fortt R, Aboagye EO. Correction: Preclinical Assessment of Carboplatin Treatment Efficacy in Lung Cancer by 18F-ICMT-11-Positron Emission Tomography. Plos One. 15: e0235804. PMID 32645089 DOI: 10.1371/journal.pone.0235804 |
0.54 |
|
| 2019 |
Gendron T, Pereira R, Abdi HY, Witney TH, Årstad E. Iron(II)/Persulfate Mediated Newman-Kwart Rearrangement. Organic Letters. PMID 31851521 DOI: 10.1021/acs.orglett.9b04280 |
0.728 |
|
| 2019 |
Glaser M, Rajkumar V, Diocou S, Gendron T, Yan R, Sin PKB, Sander K, Carroll L, Pedley RB, Aboagye EO, Witney TH, Årstad E. One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[I]iodo-1,2,3-triazole derived Isatin SPECT Tracer. Scientific Reports. 9: 19299. PMID 31848442 DOI: 10.1038/s41598-019-55992-0 |
0.545 |
|
| 2019 |
Kimura RH, Wang L, Shen B, Huo L, Tummers W, Filipp FV, Guo HH, Haywood T, Abou-Elkacem L, Baratto L, Habte F, Devulapally R, Witney TH, Cheng Y, Tikole S, et al. Evaluation of integrin αvβ cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nature Communications. 10: 4673. PMID 31611594 DOI: 10.1038/S41467-019-11863-W |
0.768 |
|
| 2019 |
Greenwood HE, Nyitrai Z, Mocsai G, Hobor S, Witney TH. High throughput PET/CT imaging using a multiple mouse imaging system. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31519806 DOI: 10.2967/jnumed.119.228692 |
0.696 |
|
| 2019 |
Shuhendler A, Cui L, Chen Z, Shen B, James ML, Witney T, Gambhir SS, Chin FT, Bazalova-Carter M, Graves E, Rao J, Chen M. [18F]-SuPAR: A radiofluorinated probe for non-invasive imaging of DNA damage-dependent Poly (ADP-ribose) Polymerase Activity. Bioconjugate Chemistry. PMID 30973715 DOI: 10.1021/Acs.Bioconjchem.9B00089 |
0.68 |
|
| 2019 |
Witney TH, Lewis DY. Imaging Cancer Metabolism with Positron Emission Tomography (PET). Methods in Molecular Biology (Clifton, N.J.). 1928: 29-44. PMID 30725448 DOI: 10.1007/978-1-4939-9027-6_2 |
0.342 |
|
| 2019 |
Greenwood HE, McCormick PN, Gendron T, Glaser M, Pereira R, Maddocks ODK, Sander K, Zhang T, Koglin N, Lythgoe MF, Årstad E, Hochhauser D, Witney TH. Measurement of tumor antioxidant capacity and prediction of chemotherapy resistance in preclinical models of ovarian cancer by positron emission tomography. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30651275 DOI: 10.1158/1078-0432.CCR-18-3423 |
0.782 |
|
| 2019 |
Greenwood H, Edwards R, Witney T. A beginner's guide to imaging in vivo tumour biochemistry The Biochemist. 41: 42-47. DOI: 10.1042/bio04104042 |
0.634 |
|
| 2018 |
Pereira R, Gendron T, Sanghera C, Greenwood HE, Newcombe J, McCormick PN, Sander K, Topf M, Årstad E, Witney TH. Mapping Aldehyde Dehydrogenase 1A1 Activity using an [ F]Substrate-Based Approach. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30521138 DOI: 10.1002/Chem.201805473 |
0.781 |
|
| 2018 |
McCormick PN, Greenwood HE, Glaser M, Maddocks ODK, Gendron T, Sander K, Gowrishankar G, Hoehne A, Zhang T, Shuhendler AJ, Lewis DY, Berndt M, Koglin N, Lythgoe MF, Gambhir SS, ... ... Witney TH, et al. Assessment of tumor redox status through (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid positron emission tomography imaging of system xc- activity. Cancer Research. PMID 30401715 DOI: 10.1158/0008-5472.Can-18-2634 |
0.815 |
|
| 2018 |
Hoehne A, James ML, Alam IS, Ronald JA, Schneider B, D'Souza A, Witney TH, Andrews LE, Cropper HC, Behera D, Gowrishankar G, Ding Z, Wyss-Coray T, Chin FT, Biswal S, et al. [F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis. Journal of Neuroinflammation. 15: 55. PMID 29471880 DOI: 10.1186/S12974-018-1080-1 |
0.76 |
|
| 2017 |
Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM. Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models. Ejnmmi Research. 7: 99. PMID 29247446 DOI: 10.1186/S13550-017-0349-1 |
0.595 |
|
| 2017 |
Schelhaas S, Heinzmann K, Honess DJ, Smith DM, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH. 3'-Deoxy-3'-[(18)F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 28971330 DOI: 10.1007/s11307-017-1125-3 |
0.61 |
|
| 2017 |
Neves AA, Xie B, Fawcett S, Alam IS, Witney TH, de Backer MM, Summers J, Hughes W, McGuire S, Soloviev D, Miller J, Howat WJ, Hu DE, Rodrigues TB, Lewis DY, et al. Rapid Imaging of Tumor Cell Death in vivo using the C2A domain of Synaptotagmin-I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28209913 DOI: 10.2967/Jnumed.116.183004 |
0.747 |
|
| 2017 |
Keu KV, Witney TH, Yaghoubi S, Rosenberg J, Kurien A, Magnusson R, Williams J, Habte F, Wagner JR, Forman S, Brown C, Allen-Auerbach M, Czernin J, Tang W, Jensen MC, et al. Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma. Science Translational Medicine. 9. PMID 28100832 DOI: 10.1126/Scitranslmed.Aag2196 |
0.8 |
|
| 2016 |
Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM. The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models. Ejnmmi Research. 6: 63. PMID 27515446 DOI: 10.1186/S13550-016-0218-3 |
0.66 |
|
| 2016 |
Merchant S, Allott L, Carroll L, Tittrea V, Kealey S, Witney TH, Miller PW, Smith G, Aboagye EO. Synthesis and pre-clinical evaluation of a [18F]fluoromethyl-tanaproget derivative for imaging of progesterone receptor expression Rsc Advances. 6: 57569-57579. DOI: 10.1039/C6RA07404A |
0.52 |
|
| 2015 |
Chang E, Pohling C, Natarajan A, Witney TH, Kaur J, Xu L, Gowrishankar G, L D'Souza A, Murty S, Schick S, Chen L, Wu N, Khaw P, Mischel P, Abbasi T, et al. AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models. Journal of Neuro-Oncology. PMID 26650066 DOI: 10.1007/S11060-015-1972-1 |
0.772 |
|
| 2015 |
Witney TH, James ML, Shen B, Chang E, Pohling C, Arksey N, Hoehne A, Shuhendler A, Park JH, Bodapati D, Weber J, Gowrishankar G, Rao J, Chin FT, Gambhir SS. PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2. Science Translational Medicine. 7: 310ra169. PMID 26491079 DOI: 10.1126/Scitranslmed.Aac6117 |
0.794 |
|
| 2015 |
Witney TH, Hoehne A, Reeves RE, Ilovich O, Namavari M, Shen B, Chin FT, Rao J, Gambhir SS. A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25972517 DOI: 10.1158/1078-0432.Ccr-14-3176 |
0.81 |
|
| 2015 |
Chang E, Pohling C, Natarajan A, Witney T, Kaur J, Xu L, Gowrishankar G, de Souza A, Schick S, Chan L, Wu N, Khaw P, Mischel P, Abbasi T, Usmani S, et al. DDEL-04AshwaMAX AND WITHAFERIN A INHIBITS GLIOMAS IN CELLULAR AND MURINE ORTHOTOPIC MODELS Neuro-Oncology. 17: v73.4-v73. DOI: 10.1093/Neuonc/Nov212.04 |
0.77 |
|
| 2014 |
Witney TH, Pisaneschi F, Alam IS, Trousil S, Kaliszczak M, Twyman F, Brickute D, Nguyen QD, Schug Z, Gottlieb E, Aboagye EO. Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection Journal of Nuclear Medicine. 55: 1506-1512. PMID 25012458 DOI: 10.2967/jnumed.114.140343 |
0.801 |
|
| 2014 |
Witney TH, Fortt R, Fortt RR, Aboagye EO. Preclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomography. Plos One. 9: e91694. PMID 24618809 DOI: 10.1371/journal.pone.0091694 |
0.598 |
|
| 2014 |
Witney TH, Carroll L, Alam IS, Chandrashekran A, Nguyen QD, Sala R, Harris R, DeBerardinis RJ, Agarwal R, Aboagye EO. A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography. Cancer Research. 74: 1319-28. PMID 24590807 DOI: 10.1158/0008-5472.CAN-13-2768 |
0.803 |
|
| 2014 |
Alam IS, Witney TH, Tomasi G, Carroll L, Twyman FJ, Nguyen QD, Aboagye EO. Radiolabeled RGD tracer kinetics annotates differential αvβ3 integrin expression linked to cell intrinsic and vessel expression Molecular Imaging and Biology. 16: 558-566. PMID 24310722 DOI: 10.1007/s11307-013-0710-3 |
0.751 |
|
| 2014 |
Schug Z, Peck B, Jones D, Zhang Q, Alam I, Witney T, Smethurst E, Grosskurth S, Harris A, Critchlow S, Aboagye E, Wakelam M, Schulze A, Gottlieb E. Acetyl-coA synthetase 2 promotes acetate utilization and maintains cell growth under metabolic stress Cancer and Metabolism. 2: 1-1. DOI: 10.1186/2049-3002-2-S1-O9 |
0.706 |
|
| 2014 |
Merchant S, Witney TH, Aboagye EO. Imaging as a pharmacodynamic and response biomarker in cancer Clinical and Translational Imaging. 2: 13-31. DOI: 10.1007/s40336-014-0049-z |
0.483 |
|
| 2013 |
Pisaneschi F, Witney TH, Iddon L, Aboagye EO. Synthesis of [18F]fluoro-pivalic acid: an improved PET imaging probe for the fatty acid synthesis pathway in tumours Medchemcomm. 4: 1350. DOI: 10.1039/C3MD00169E |
0.543 |
|
| 2013 |
Carroll L, Witney TH, Aboagye EO. Design and synthesis of novel 18F-radiolabelled glucosamine derivatives for cancer imaging Medchemcomm. 4: 653. DOI: 10.1039/C3MD00023K |
0.567 |
|
| 2012 |
Clatworthy MR, Kettunen MI, Hu DE, Mathews RJ, Witney TH, Kennedy BW, Bohndiek SE, Gallagher FA, Jarvis LB, Smith KG, Brindle KM. Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 13374-9. PMID 22837393 DOI: 10.1073/pnas.1205539109 |
0.635 |
|
| 2012 |
Witney TH, Alam IS, Turton DR, Smith G, Carroll L, Brickute D, Twyman FJ, Nguyen QD, Tomasi G, Awais RO, Aboagye EO. Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography Clinical Cancer Research. 18: 1063-1072. PMID 22235095 DOI: 10.1158/1078-0432.CCR-11-2462 |
0.779 |
|
| 2011 |
Witney TH, Kettunen MI, Brindle KM. Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells. The Journal of Biological Chemistry. 286: 24572-80. PMID 21596745 DOI: 10.1074/jbc.M111.237727 |
0.474 |
|
| 2010 |
Bohndiek SE, Kettunen MI, Hu DE, Witney TH, Kennedy BW, Gallagher FA, Brindle KM. Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy. Molecular Cancer Therapeutics. 9: 3278-88. PMID 21159611 DOI: 10.1158/1535-7163.MCT-10-0706 |
0.674 |
|
| 2010 |
Witney TH, Kettunen MI, Hu DE, Gallagher FA, Bohndiek SE, Napolitano R, Brindle KM. Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate. British Journal of Cancer. 103: 1400-6. PMID 20924379 DOI: 10.1038/sj.bjc.6605945 |
0.663 |
|
| 2010 |
Witney TH, Brindle KM. Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy. Biochemical Society Transactions. 38: 1220-4. PMID 20863288 DOI: 10.1042/BST0381220 |
0.51 |
|
| 2010 |
Alam IS, Neves AA, Witney TH, Boren J, Brindle KM. Comparison of the C2A domain of synaptotagmin-I and annexin-V as probes for detecting cell death. Bioconjugate Chemistry. 21: 884-91. PMID 20402461 DOI: 10.1021/bc9004415 |
0.718 |
|
| 2010 |
Kettunen MI, Hu DE, Witney TH, McLaughlin R, Gallagher FA, Bohndiek SE, Day SE, Brindle KM. Magnetization transfer measurements of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma. Magnetic Resonance in Medicine. 63: 872-80. PMID 20373388 DOI: 10.1002/mrm.22276 |
0.633 |
|
| 2009 |
Gallagher FA, Kettunen MI, Hu DE, Jensen PR, Zandt RIt, Karlsson M, Gisselsson A, Nelson SK, Witney TH, Bohndiek SE, Hansson G, Peitersen T, Lerche MH, Brindle KM. Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors Proceedings of the National Academy of Sciences of the United States of America. 106: 19801-19806. PMID 19903889 DOI: 10.1073/pnas.0911447106 |
0.694 |
|
| 2009 |
Witney TH, Kettunen MI, Day SE, Hu DE, Neves AA, Gallagher FA, Fulton SM, Brindle KM. A comparison between radiolabeled fluorodeoxyglucose uptake and hyperpolarized (13)C-labeled pyruvate utilization as methods for detecting tumor response to treatment. Neoplasia (New York, N.Y.). 11: 574-82, 1 p followin. PMID 19484146 DOI: 10.1593/NEO.09254 |
0.598 |
|
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