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Manfred Wuhrer - Publications

Affiliations: 
Leiden University Medical Center, Leiden, Netherlands 
Area:
mass spectrometry
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279 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Falck D, Wuhrer M. GlYcoLISA: antigen-specific and subclass-specific IgG Fc glycosylation analysis based on an immunosorbent assay with an LC-MS readout. Nature Protocols. PMID 38383719 DOI: 10.1038/s41596-024-00963-7  0.342
2023 Blöchl C, Gstöttner C, Sénard T, Stork EM, Scherer HU, Toes REM, Wuhrer M, Domínguez-Vega E. A robust nanoscale RP HPLC-MS approach for sensitive Fc proteoform profiling of IgG allotypes. Analytica Chimica Acta. 1279: 341795. PMID 37827688 DOI: 10.1016/j.aca.2023.341795  0.313
2022 Grunert I, Heinrich K, Hingar M, Ernst J, Winter M, Bomans K, Wagner K, Fevre A, Reusch D, Wuhrer M, Bulau P. Comprehensive Multidimensional Liquid Chromatography-Mass Spectrometry for the Characterization of Charge Variants of a Bispecific Antibody. Journal of the American Society For Mass Spectrometry. PMID 36442848 DOI: 10.1021/jasms.2c00296  0.307
2022 Šuštić T, Van Coillie J, Larsen MD, Derksen NIL, Szittner Z, Nouta J, Wang W, Damelang T, Rebergen I, Linty F, Visser R, Mok JY, Geerdes DM, van Esch WJE, de Taeye SW, ... ... Wuhrer M, et al. Immunoassay for quantification of antigen-specific IgG fucosylation. Ebiomedicine. 81: 104109. PMID 35752106 DOI: 10.1016/j.ebiom.2022.104109  0.339
2021 Lippold S, Knaupp A, de Ru AH, Tjokrodirijo RTN, van Veelen PA, van Puijenbroek E, de Taeye SW, Reusch D, Vidarsson G, Wuhrer M, Schlothauer T, Falck D. Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography-mass spectrometry. Mabs. 13: 1982847. PMID 34674601 DOI: 10.1080/19420862.2021.1982847  0.31
2021 Falck D, Thomann M, Lechmann M, Koeleman CAM, Malik S, Jany C, Wuhrer M, Reusch D. Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody. Mabs. 13: 1865596. PMID 33382957 DOI: 10.1080/19420862.2020.1865596  0.319
2021 Wang W, Kałuża A, Nouta J, Nicolardi S, Ferens-Sieczkowska M, Wuhrer M, Lageveen-Kammeijer GSM, de Haan N. High-throughput glycopeptide profiling of prostate-specific antigen from seminal plasma by MALDI-MS. Talanta. 222: 121495. PMID 33167210 DOI: 10.1016/J.Talanta.2020.121495  0.358
2020 Gstöttner C, Nicolardi S, Haberger M, Reusch D, Wuhrer M, Domínguez-Vega E. Intact and subunit-specific analysis of bispecific antibodies by sheathless CE-MS. Analytica Chimica Acta. 1134: 18-27. PMID 33059862 DOI: 10.1016/J.Aca.2020.07.069  0.414
2020 Sénard T, Gargano AFG, Falck D, de Taeye SW, Rispens T, Vidarsson G, Wuhrer M, Somsen GW, Domínguez-Vega E. MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc -Glycosylation. Frontiers in Immunology. 11: 2049. PMID 32973813 DOI: 10.3389/Fimmu.2020.02049  0.442
2020 Amez-Martín M, Wuhrer M, Falck D. Immunoglobulin G Glycoprofiles are Unaffected by Common Bottom-Up Sample Processing. Journal of Proteome Research. 19: 4158-4162. PMID 32945168 DOI: 10.1021/Acs.Jproteome.0C00656  0.341
2020 Gstöttner C, Vergoossen DLE, Wuhrer M, Huijbers MGM, Domínguez-Vega E. Sheathless CE-MS as a tool for monitoring exchange efficiency and stability of bispecific antibodies. Electrophoresis. PMID 32901958 DOI: 10.1002/Elps.202000166  0.417
2020 Vreeker GCM, Hanna-Sawires RG, Mohammed Y, Bladergroen MR, Nicolardi S, Dotz V, Nouta J, Bonsing BA, Mesker WE, van der Burgt YEM, Wuhrer M, Tollenaar RAEM. Serum N-Glycome analysis reveals pancreatic cancer disease signatures. Cancer Medicine. PMID 32898301 DOI: 10.1002/Cam4.3439  0.31
2020 Wojcik I, Sénard T, de Graaf E, Janssen G, de Ru A, Mohammed Y, van Veelen PA, Vidarsson G, Wuhrer M, Falck D. Site-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of individual healthy donors. Analytical Chemistry. PMID 32886488 DOI: 10.1021/Acs.Analchem.0C02342  0.426
2020 Zeeuw van der Laan EAN, van der Velden S, Bentlage AEH, Larsen MD, van Osch TLJ, Mok JY, Brasser G, Geerdes DM, Koeleman CAM, Nouta J, Semple JW, Porcelijn L, van Esch WJE, Wuhrer M, van der Schoot CE, et al. Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation. Blood Advances. 4: 3875-3885. PMID 32810222 DOI: 10.1182/Bloodadvances.2020002291  0.363
2020 Nicolardi S, Kilgour DPA, van der Burgt YEM, Wuhrer M. Improved N- and C-Terminal Sequencing of Proteins by Combining Positive and Negative Ion MALDI In-Source Decay Mass Spectrometry. Analytical Chemistry. PMID 32803948 DOI: 10.1021/Acs.Analchem.0C02198  0.328
2020 Pirro M, Mohammed Y, van Vliet SJ, Rombouts Y, Sciacca A, de Ru AH, Janssen GMC, Tjokrodirijo RTN, Wuhrer M, van Veelen PA, Hensbergen PJ. -Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity. International Journal of Molecular Sciences. 21. PMID 32752259 DOI: 10.3390/Ijms21155522  0.322
2020 Clauder AK, Kordowski A, Bartsch YC, Köhl G, Lilienthal GM, Almeida LN, Lindemann T, Petry J, Rau CN, Gramalla-Schmitz A, Dühring L, Elbracht C, Kenno S, Tillmann J, Wuhrer M, et al. IgG Fc N-glycosylation translates MHCII haplotype into autoimmune skin disease. The Journal of Investigative Dermatology. PMID 32653301 DOI: 10.1016/J.Jid.2020.06.022  0.353
2020 Benedetti E, Gerstner N, Pučić-Baković M, Keser T, Reiding KR, Ruhaak LR, Štambuk T, Selman MHJ, Rudan I, Polašek O, Hayward C, Beekman M, Slagboom E, Wuhrer M, Dunlop MG, et al. Systematic Evaluation of Normalization Methods for Glycomics Data Based on Performance of Network Inference. Metabolites. 10. PMID 32630764 DOI: 10.3390/Metabo10070271  0.332
2020 Zhang T, van Die I, Tefsen B, van Vliet SJ, Laan LC, Zhang J, Ten Dijke P, Wuhrer M, Belo AI. Differential - and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior. Frontiers in Oncology. 10: 732. PMID 32582529 DOI: 10.3389/Fonc.2020.00732  0.316
2020 Lippold S, Buettner A, Choo MSF, Hook M, de Jong CJ, Nguyen-Khuong T, Haberger M, Reusch D, Wuhrer M, de Haan N. Cysteine aminoethylation enables site-specific glycosylation analysis of recombinant human erythropoietin using trypsin. Analytical Chemistry. PMID 32578997 DOI: 10.1021/Acs.Analchem.0C01794  0.334
2020 Bartsch YC, Eschweiler S, Leliavski A, Lunding HB, Wagt S, Petry J, Lilienthal GM, Rahmöller J, de Haan N, Hölscher A, Erapaneedi R, Giannou AD, Aly L, Sato R, de Neef LA, ... ... Wuhrer M, et al. IgG Fc sialylation is regulated during the germinal center reaction upon immunization with different adjuvants. The Journal of Allergy and Clinical Immunology. PMID 32445838 DOI: 10.1016/J.Jaci.2020.04.059  0.371
2020 de Taeye SW, Bentlage AEH, Mebius MM, Meesters JI, Lissenberg-Thunnissen S, Falck D, Sénard T, Salehi N, Wuhrer M, Schuurman J, Labrijn AF, Rispens T, Vidarsson G. FcγR Binding and ADCC Activity of Human IgG Allotypes. Frontiers in Immunology. 11: 740. PMID 32435243 DOI: 10.3389/Fimmu.2020.00740  0.379
2020 Heijs B, Holst-Bernal S, de Graaff MA, Briaire-de Bruijn IH, Rodriguez-Girondo M, van de Sande MAJ, Wuhrer M, McDonnell LA, Bovée JVMG. Molecular signatures of tumor progression in myxoid liposarcoma identified by N-glycan mass spectrometry imaging. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 32341520 DOI: 10.1038/S41374-020-0435-2  0.337
2020 Madunić K, Zhang T, Mayboroda OA, Holst S, Stavenhagen K, Jin C, Karlsson NG, Lageveen-Kammeijer GSM, Wuhrer M. Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype. Cellular and Molecular Life Sciences : Cmls. PMID 32236654 DOI: 10.1007/S00018-020-03504-Z  0.341
2020 Nicolardi S, Kilgour DPA, Dolezal N, Drijfhout JW, Wuhrer M, van der Burgt YEM. Evaluation of Sibling and Twin Fragment Ions Improves the Structural Characterization of Proteins by Top-Down MALDI In-Source Decay Mass Spectrometry. Analytical Chemistry. PMID 32212639 DOI: 10.1021/Acs.Analchem.9B05683  0.34
2020 Rebello OD, Nicolardi S, Lageveen-Kammeijer GSM, Nouta J, Gardner RA, Mesker WE, Tollenaar RAEM, Spencer DIR, Wuhrer M, Falck D. A Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Assay for the Relative Quantitation of Antennary Fucosylated -Glycans in Human Plasma. Frontiers in Chemistry. 8: 138. PMID 32185163 DOI: 10.3389/Fchem.2020.00138  0.373
2020 Klarić L, Tsepilov YA, Stanton CM, Mangino M, Sikka TT, Esko T, Pakhomov E, Salo P, Deelen J, McGurnaghan SJ, Keser T, Vučković F, Ugrina I, Krištić J, Gudelj I, ... ... Wuhrer M, et al. Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases. Science Advances. 6: eaax0301. PMID 32128391 DOI: 10.1126/Sciadv.Aax0301  0.319
2020 van Erp EA, Lakerveld AJ, de Graaf E, Larsen MD, Schepp RM, Hipgrave Ederveen AL, Ahout IM, de Haan CA, Wuhrer M, Luytjes W, Ferwerda G, Vidarsson G, van Kasteren PB. Natural killer cell activation by respiratory syncytial virus-specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc-glycosylation. Clinical & Translational Immunology. 9: e1112. PMID 32099650 DOI: 10.1002/Cti2.1112  0.332
2020 Momčilović A, de Haan N, Hipgrave Ederveen AL, Bondt A, Koeleman CAM, Falck D, de Neef LA, Mesker WE, Tollenaar R, de Ru A, van Veelen P, Wuhrer M, Dotz V. Simultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications. Analytical Chemistry. 92: 4518-4526. PMID 32091889 DOI: 10.1021/Acs.Analchem.9B05722  0.425
2020 Schmidt DE, de Haan N, Sonneveld ME, Porcelijn L, van der Schoot CE, de Haas M, Zwaginga JJ, Wuhrer M, Vidarsson G. IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia. Scientific Reports. 10: 3051. PMID 32080262 DOI: 10.1038/S41598-020-59651-7  0.402
2020 Kumpel BM, Saldova R, Koeleman CAM, Abrahams JL, Ederveen AH, Armour KL, Olovnikova NI, Vidarsson G, Kapur R, Rudd PM, Wuhrer M. Anti-D monoclonal antibodies from 23 human and rodent cell lines display diverse IgG Fc-glycosylation profiles that determine their clinical efficacy. Scientific Reports. 10: 1464. PMID 32001734 DOI: 10.1038/S41598-019-57393-9  0.354
2020 Steffen U, Koeleman CA, Sokolova MV, Bang H, Kleyer A, Rech J, Unterweger H, Schicht M, Garreis F, Hahn J, Andes FT, Hartmann F, Hahn M, Mahajan A, Paulsen F, ... ... Wuhrer M, et al. IgA subclasses have different effector functions associated with distinct glycosylation profiles. Nature Communications. 11: 120. PMID 31913287 DOI: 10.1038/S41467-019-13992-8  0.351
2020 Vreeker GCM, Nicolardi S, Madunic K, Kotsias M, Burgt YEMvd, Wuhrer M. O- and N-glycosylation analysis of cell lines by ultrahigh resolution MALDI-FTICR-MS International Journal of Mass Spectrometry. 448: 116267. DOI: 10.1016/J.Ijms.2019.116267  0.396
2020 Haan Nd, Wuhrer M, Ruhaak LR. Mass spectrometry in clinical glycomics: The path from biomarker identification to clinical implementation Clinical Mass Spectrometry. 18: 1-12. DOI: 10.1016/J.Clinms.2020.08.001  0.311
2019 Lippold S, Nicolardi S, Wuhrer M, Falck D. Proteoform-Resolved FcɤRIIIa Binding Assay for Fab Glycosylated Monoclonal Antibodies Achieved by Affinity Chromatography Mass Spectrometry of Fc Moieties. Frontiers in Chemistry. 7: 698. PMID 31709228 DOI: 10.3389/Fchem.2019.00698  0.457
2019 Gstöttner C, Reusch D, Haberger M, Dragan I, van Veelen P, Kilgour DPA, Tsybin YO, van der Burgt YEM, Wuhrer M, Nicolardi S. Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh resolution MALDI FT-ICR mass spectrometry. Mabs. PMID 31630606 DOI: 10.1080/19420862.2019.1682403  0.384
2019 De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y, Sosic Z, Zhang P, Altmann F, Gruber C, Shao C, ... ... Wuhrer M, et al. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Molecular & Cellular Proteomics : McP. PMID 31591262 DOI: 10.1074/Mcp.Ra119.001677  0.366
2019 Wuhrer M. Paucity of Paucimannosylation Revoked. Proteomics. e1900244. PMID 31532879 DOI: 10.1002/Pmic.201900244  0.318
2019 Dotz V, Wuhrer M. N-glycome signatures in human plasma: associations with physiology and major diseases. Febs Letters. PMID 31509238 DOI: 10.1002/1873-3468.13598  0.347
2019 Vreeker GCM, Bladergroen MR, Nicolardi S, Mesker WE, Tollenaar RAEM, van der Burgt YEM, Wuhrer M. Dried blood spot N-glycome analysis by MALDI mass spectrometry. Talanta. 205: 120104. PMID 31450448 DOI: 10.1016/J.Talanta.2019.06.104  0.371
2019 Stavenhagen K, Gahoual R, Dominguez Vega E, Palmese A, Ederveen ALH, Cutillo F, Palinsky W, Bierau H, Wuhrer M. Site-specific N- and O-glycosylation analysis of atacicept. Mabs. 11: 1053-1063. PMID 31349756 DOI: 10.1080/19420862.2019.1630218  0.361
2019 Tyshchuk O, Gstöttner C, Funk D, Nicolardi S, Frost S, Klostermann S, Becker T, Jolkver E, Schumacher F, Koller CF, Völger HR, Wuhrer M, Bulau P, Mølhøj M. Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics. Mabs. 1-14. PMID 31339437 DOI: 10.1080/19420862.2019.1635865  0.366
2019 Rojas-Macias MA, Mariethoz J, Andersson P, Jin C, Venkatakrishnan V, Aoki NP, Shinmachi D, Ashwood C, Madunic K, Zhang T, Miller RL, Horlacher O, Struwe WB, Watanabe Y, Okuda S, ... ... Wuhrer M, et al. Towards a standardized bioinformatics infrastructure for N- and O-glycomics. Nature Communications. 10: 3275. PMID 31332201 DOI: 10.1038/S41467-019-11131-X  0.381
2019 Temming AR, Dekkers G, van de Bovenkamp FS, Plomp HR, Bentlage AEH, Szittner Z, Derksen NIL, Wuhrer M, Rispens T, Vidarsson G. Human DC-SIGN and CD23 do not interact with human IgG. Scientific Reports. 9: 9995. PMID 31292524 DOI: 10.1038/S41598-019-46484-2  0.324
2019 de Haan N, Falck D, Wuhrer M. Monitoring of Immunoglobulin N- and O-glycosylation in Health and Disease. Glycobiology. PMID 31281930 DOI: 10.1093/Glycob/Cwz048  0.469
2019 Lippold S, Nicolardi S, Domínguez-Vega E, Heidenreich AK, Vidarsson G, Reusch D, Haberger M, Wuhrer M, Falck D. Glycoform-resolved FcɣRIIIa affinity chromatography-mass spectrometry. Mabs. 11: 1191-1196. PMID 31276431 DOI: 10.1080/19420862.2019.1636602  0.426
2019 Marti Fernandez I, Macrini C, Krumbholz M, Hensbergen PJ, Hipgrave Ederveen AL, Winklmeier S, Vural A, Kurne A, Jenne D, Kamp F, Gerdes LA, Hohlfeld R, Wuhrer M, Kümpfel T, Meinl E. The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients. Frontiers in Immunology. 10: 1189. PMID 31244828 DOI: 10.3389/Fimmu.2019.01189  0.381
2019 Lageveen-Kammeijer GSM, de Haan N, Mohaupt P, Wagt S, Filius M, Nouta J, Falck D, Wuhrer M. Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples. Nature Communications. 10: 2137. PMID 31086181 DOI: 10.1038/S41467-019-09910-7  0.385
2019 Hafkenscheid L, de Moel E, Smolik I, Tanner S, Meng X, Jansen BC, Bondt A, Wuhrer M, Huizinga TWJ, Toes REM, El-Gabalawy H, Scherer HU. N-linked glycans in the variable domain of ACPA-IgG predict the development of rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31067000 DOI: 10.1002/Art.40920  0.356
2019 Zhang Z, Westhrin M, Bondt A, Wuhrer M, Standal T, Holst S. Serum protein N-glycosylation changes in multiple myeloma. Biochimica Et Biophysica Acta. General Subjects. 1863: 960-970. PMID 30844485 DOI: 10.1016/J.Bbagen.2019.03.001  0.369
2019 Kotsias M, Kozak RP, Gardner RA, Wuhrer M, Spencer DIR. Improved and semi-automated reductive β-elimination workflow for higher throughput protein O-glycosylation analysis. Plos One. 14: e0210759. PMID 30653606 DOI: 10.1371/Journal.Pone.0210759  0.313
2019 van der Burgt YEM, Kilgour DPA, Tsybin YO, Srzentić K, Fornelli L, Beck A, Wuhrer M, Nicolardi S. Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry. Analytical Chemistry. 91: 2079-2085. PMID 30571088 DOI: 10.1021/Acs.Analchem.8B04515  0.422
2019 Hafkenscheid L, Moel ECd, Smolik I, Meng X, Tanner S, Jansen BC, Bondt A, Wuhrer M, Huizinga T, Toes R, El-Gabalawy H, Scherer HU. Op0295 N-Linked Glycans In The Variable Domain Of Acpa-Igg In The Development Of Rheumatoid Arthritis Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2019-Eular.7067  0.318
2018 Pirro M, Schoof E, van Vliet SJ, Rombouts Y, Stella A, de Ru A, Mohammed Y, Wuhrer M, van Veelen PA, Hensbergen PJ. Glycoproteomic analysis of MGL binding proteins on acute T cell leukemia cells. Journal of Proteome Research. PMID 30582698 DOI: 10.1021/Acs.Jproteome.8B00796  0.342
2018 Plomp R, de Haan N, Bondt A, Murli J, Dotz V, Wuhrer M. Comparative Glycomics of Immunoglobulin A and G From Saliva and Plasma Reveals Biomarker Potential. Frontiers in Immunology. 9: 2436. PMID 30405629 DOI: 10.3389/Fimmu.2018.02436  0.427
2018 Culver EL, van de Bovenkamp FS, Derksen NIL, Koers J, Cargill T, Barnes E, de Neef LA, Koeleman CAM, Aalberse RC, Wuhrer M, Rispens T. Unique patterns of glycosylation in IgG4-related disease and primary sclerosing cholangitis. Journal of Gastroenterology and Hepatology. PMID 30345709 DOI: 10.1111/Jgh.14512  0.36
2018 Reiding KR, Bondt A, Hennig R, Gardner RA, O'Flaherty R, Trbojević-Akmačić I, Shubhakar A, Hazes J, Reichl U, Fernandes DL, Pucic-Bakovic M, Rapp E, Spencer DIR, Dolhain R, Rudd P, ... ... Wuhrer M, et al. High-throughput serum -glycomics: method comparison and application to study rheumatoid arthritis and pregnancy-associated changes. Molecular & Cellular Proteomics : McP. PMID 30242110 DOI: 10.1074/Mcp.Ra117.000454  0.419
2018 Vreeker GCM, Nicolardi S, Bladergroen MR, van der Plas CJ, Mesker WE, Tollenaar RAEM, van der Burgt YEM, Wuhrer M. Automated Plasma Glycomics with Linkage-Specific Sialic Acid Esterification and Ultrahigh Resolution MS. Analytical Chemistry. 90: 11955-11961. PMID 30230816 DOI: 10.1021/Acs.Analchem.8B02391  0.385
2018 de Vroome SW, Holst S, Girondo MR, van der Burgt YEM, Mesker WE, Tollenaar RAEM, Wuhrer M. Serum -glycome alterations in colorectal cancer associate with survival. Oncotarget. 9: 30610-30623. PMID 30093973 DOI: 10.18632/Oncotarget.25753  0.302
2018 Lauc G, Vučković F, Bondt A, Pezer M, Wuhrer M. Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG. Nature Communications. 9: 2916. PMID 30046098 DOI: 10.1038/S41467-018-05173-W  0.318
2018 Jansen BC, Hafkenscheid L, Bondt A, Gardner RA, Hendel JL, Wuhrer M, Spencer DIR. HappyTools: A software for high-throughput HPLC data processing and quantitation. Plos One. 13: e0200280. PMID 29979768 DOI: 10.1371/Journal.Pone.0200280  0.3
2018 van Schie KA, Kruithof S, Ooijevaar-de Heer P, Derksen NIL, van de Bovenkamp FS, Saris A, Vidarsson G, Bentlage AEH, Jiskoot W, Romeijn S, Koning RI, Bos E, Stork EM, Koeleman CAM, Wuhrer M, et al. Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies. Annals of the Rheumatic Diseases. 77: 1471-1479. PMID 29945923 DOI: 10.1136/Annrheumdis-2018-213299  0.331
2018 de Haan N, Boeddha NP, Ekinci E, Reiding KR, Emonts M, Hazelzet JA, Wuhrer M, Driessen GJ. Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis. Mbio. 9. PMID 29921663 DOI: 10.1128/Mbio.00546-18  0.336
2018 de Haan N, van Tol MJD, Driessen GJ, Wuhrer M, Lankester AC. Immunoglobulin G Fragment Crystallizable Glycosylation After Hematopoietic Stem Cell Transplantation Is Dissimilar to Donor Profiles. Frontiers in Immunology. 9: 1238. PMID 29915589 DOI: 10.3389/Fimmu.2018.01238  0.316
2018 Clerc F, Novokmet M, Dotz V, Reiding KR, de Haan N, Kammeijer GSM, Dalebout H, Bladergroen MR, Vukovic F, Rapp E, Targan SR, Barron G, Manetti N, Latiano A, ... ... Wuhrer M, et al. Plasma N-Glycan Signatures Are Associated With Features of Inflammatory Bowel Diseases. Gastroenterology. 155: 829-843. PMID 29792883 DOI: 10.1053/J.Gastro.2018.05.030  0.308
2018 Knopf J, Magorivska I, Maler JM, Spitzer P, Bilyy R, Biermann MHC, Hychka K, Bondt A, Wuhrer M, Toes REM, Schett G, Herrmann M, Muñoz LE. Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG. Journal of Neuroimmunology. 320: 19-24. PMID 29759137 DOI: 10.1016/J.Jneuroim.2018.04.010  0.37
2018 Bondt A, Hafkenscheid L, Falck D, Kuijper TM, Rombouts Y, Hazes JMW, Wuhrer M, Dolhain RJEM. ACPA IgG galactosylation associates with disease activity in pregnant patients with rheumatoid arthritis. Annals of the Rheumatic Diseases. 77: 1130-1136. PMID 29615411 DOI: 10.1136/Annrheumdis-2018-212946  0.311
2018 Jacobino SR, Nederend M, Reijneveld JF, Augustijn D, Jansen JHM, Meeldijk J, Reiding KR, Wuhrer M, Coenjaerts FEJ, Hack CE, Bont LJ, Leusen JHW. Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo. Mabs. 10: 453-462. PMID 29553863 DOI: 10.1080/19420862.2018.1433974  0.349
2018 Wahl A, van den Akker E, Klaric L, Štambuk J, Benedetti E, Plomp R, Razdorov G, Trbojević-Akmačić I, Deelen J, van Heemst D, Slagboom PE, Vučković F, Grallert H, Krumsiek J, Strauch K, ... ... Wuhrer M, et al. Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns. Frontiers in Immunology. 9: 277. PMID 29535710 DOI: 10.3389/Fimmu.2018.00277  0.391
2018 Kammeijer GSM, Nouta J, de la Rosette JJMCH, de Reijke TM, Wuhrer M. An In-Depth Glycosylation Assay for Urinary Prostate-Specific Antigen. Analytical Chemistry. 90: 4414-4421. PMID 29502397 DOI: 10.1021/Acs.Analchem.7B04281  0.331
2018 Link-Lenczowski P, Bubka M, Balog CIA, Koeleman CAM, Butters TD, Wuhrer M, Lityńska A. The glycomic effect of N-acetylglucosaminyltransferase III overexpression in metastatic melanoma cells. GnT-III modifies highly branched N-glycans. Glycoconjugate Journal. PMID 29502191 DOI: 10.1007/S10719-018-9814-Y  0.368
2018 Sonneveld ME, Koeleman CAM, Plomp HR, Wuhrer M, van der Schoot CE, Vidarsson G. Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies. Frontiers in Immunology. 9: 129. PMID 29445378 DOI: 10.3389/Fimmu.2018.00129  0.408
2018 van de Bovenkamp FS, Derksen NIL, Ooijevaar-de Heer P, van Schie KA, Kruithof S, Berkowska MA, van der Schoot CE, IJspeert H, van der Burg M, Gils A, Hafkenscheid L, Toes REM, Rombouts Y, Plomp R, Wuhrer M, et al. Adaptive antibody diversification through-linked glycosylation of the immunoglobulin variable region. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432186 DOI: 10.1073/Pnas.1711720115  0.387
2018 Dimitrov B, Himmelreich N, Hipgrave Ederveen AL, Lüchtenborg C, Okun JG, Breuer M, Hutter AM, Carl M, Guglielmi L, Hellwig A, Thiemann KC, Jost M, Peters V, Staufner C, Hoffmann GF, ... ... Wuhrer M, et al. Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG. Molecular Genetics and Metabolism. PMID 29396028 DOI: 10.1016/J.Ymgme.2018.01.008  0.317
2018 Ferrantelli E, Farhat K, Ederveen ALH, Reiding KR, Beelen RHJ, van Ittersum FJ, Wuhrer M, Dotz V. Effluent and serum protein N-glycosylation is associated with inflammation and peritoneal membrane transport characteristics in peritoneal dialysis patients. Scientific Reports. 8: 979. PMID 29343697 DOI: 10.1038/S41598-018-19147-X  0.302
2018 Stavenhagen K, Kayili HM, Holst S, Koeleman CAM, Engel R, Wouters D, Zeerleder S, Salih B, Wuhrer M. N- and -glycosylation Analysis of Human C1-inhibitor Reveals Extensive Mucin-type -Glycosylation. Molecular & Cellular Proteomics : McP. 17: 1225-1238. PMID 29233911 DOI: 10.1074/Mcp.Ra117.000240  0.395
2018 Culver E, Bovenkamp FSvd, Derksen N, Cargill T, Koeleman C, Neef L, Barnes E, Aalberse R, Wuhrer M, Rispens T. OTU-020 Altered FC and FAB glycosylation status in patients with IGG4-related sclerosing cholangitis and autoimmune pancreatitis Gut. 67. DOI: 10.1136/Gutjnl-2018-Bsgabstracts.306  0.408
2017 Reiding KR, Vreeker GCM, Bondt A, Bladergroen MR, Hazes JMW, van der Burgt YEM, Wuhrer M, Dolhain RJEM. Serum Protein -Glycosylation Changes with Rheumatoid Arthritis Disease Activity during and after Pregnancy. Frontiers in Medicine. 4: 241. PMID 29359131 DOI: 10.3389/Fmed.2017.00241  0.325
2017 Dekkers G, Bentlage AEH, Plomp R, Visser R, Koeleman CAM, Beentjes A, Mok JY, van Esch WJE, Wuhrer M, Rispens T, Vidarsson G. Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice. Molecular Immunology. 94: 54-60. PMID 29268168 DOI: 10.1016/J.Molimm.2017.12.006  0.381
2017 Holst S, Belo AI, Giovannetti E, van Die I, Wuhrer M. Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation. Scientific Reports. 7: 16623. PMID 29192278 DOI: 10.1038/S41598-017-16811-6  0.304
2017 Benedetti E, Pučić-Baković M, Keser T, Wahl A, Hassinen A, Yang JY, Liu L, Trbojević-Akmačić I, Razdorov G, Štambuk J, Klarić L, Ugrina I, Selman MHJ, Wuhrer M, Rudan I, et al. Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway. Nature Communications. 8: 1483. PMID 29133956 DOI: 10.1038/S41467-017-01525-0  0.307
2017 Wahl A, Kasela S, Monotoro EC, van Iterson M, Štambuk J, Sharma S, van den Akker E, Klaric L, Benedetti E, Razdorov G, Trbojević-Akmačić I, Vučković F, Ugrina I, Beekman M, Deelen J, ... ... Wuhrer M, et al. IgG glycosylation and DNA methylation are interconnected with smoking. Biochimica Et Biophysica Acta. PMID 29055820 DOI: 10.1016/J.Bbagen.2017.10.012  0.324
2017 Plomp R, Ruhaak LR, Uh HW, Reiding KR, Selman M, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Wuhrer M. Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health. Scientific Reports. 7: 12325. PMID 28951559 DOI: 10.1038/S41598-017-12495-0  0.385
2017 Dekkers G, Treffers L, Plomp R, Bentlage AEH, de Boer M, Koeleman CAM, Lissenberg-Thunnissen SN, Visser R, Brouwer M, Mok JY, Matlung H, van den Berg TK, van Esch WJE, Kuijpers TW, Wouters D, ... ... Wuhrer M, et al. Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities. Frontiers in Immunology. 8: 877. PMID 28824618 DOI: 10.3389/Fimmu.2017.00877  0.408
2017 Sonneveld ME, de Haas M, Koeleman C, de Haan N, Zeerleder SS, Ligthart PC, Wuhrer M, van der Schoot CE, Vidarsson G. Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation. Scientific Reports. 7: 8187. PMID 28811589 DOI: 10.1038/S41598-017-08654-Y  0.388
2017 Epp A, Hobusch J, Bartsch YC, Petry J, Lilienthal GM, Koeleman CAM, Eschweiler S, Möbs C, Hall A, Morris SC, Braumann D, Engellenner C, Bitterling J, Rahmöller J, Leliavski A, ... ... Wuhrer M, et al. Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions. The Journal of Allergy and Clinical Immunology. PMID 28728998 DOI: 10.1016/J.Jaci.2017.06.021  0.347
2017 Falck D, Haberger M, Plomp R, Hook M, Bulau P, Wuhrer M, Reusch D. Affinity purification of erythropoietin from cell culture supernatant combined with MALDI-TOF-MS analysis of erythropoietin N-glycosylation. Scientific Reports. 7: 5324. PMID 28706253 DOI: 10.1038/S41598-017-05641-1  0.429
2017 Nicolardi S, van der Burgt YEM, Codée JDC, Wuhrer M, Hokke CH, Chiodo F. Structural Characterization of Bio-Functionalized Gold Nanoparticles by Ultrahigh Resolution Mass Spectrometry. Acs Nano. PMID 28686409 DOI: 10.1021/Acsnano.7B03402  0.355
2017 Kammeijer GSM, Jansen BC, Kohler I, Heemskerk AAM, Mayboroda OA, Hensbergen PJ, Schappler J, Wuhrer M. Sialic acid linkage differentiation of glycopeptides using capillary electrophoresis - electrospray ionization - mass spectrometry. Scientific Reports. 7: 3733. PMID 28623326 DOI: 10.1038/S41598-017-03838-Y  0.38
2017 de Haan N, Reiding KR, Krištić J, Hipgrave Ederveen AL, Lauc G, Wuhrer M. The Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains. Frontiers in Immunology. 8: 608. PMID 28620376 DOI: 10.3389/Fimmu.2017.00608  0.384
2017 Bruggeman CW, Dekkers G, Bentlage AEH, Treffers LW, Nagelkerke SQ, Lissenberg-Thunnissen S, Koeleman CAM, Wuhrer M, van den Berg TK, Rispens T, Vidarsson G, Kuijpers TW. Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile. Journal of Immunology (Baltimore, Md. : 1950). 199: 204-211. PMID 28566370 DOI: 10.4049/Jimmunol.1700116  0.381
2017 Gahoual R, Heidenreich AK, Somsen GW, Bulau P, Reusch D, Wuhrer M, Haberger M. Detailed Characterization of Monoclonal Antibody Receptor Interaction Using Affinity Liquid Chromatography Hyphenated to Native Mass Spectrometry. Analytical Chemistry. 89: 5404-5412. PMID 28398745 DOI: 10.1021/Acs.Analchem.7B00211  0.397
2017 Kemna MJ, Plomp R, van Paassen P, Koeleman CAM, Jansen BC, Damoiseaux JGMC, Cohen Tervaert JW, Wuhrer M. Galactosylation and Sialylation Levels of IgG Predict Relapse in Patients With PR3-ANCA Associated Vasculitis. Ebiomedicine. 17: 108-118. PMID 28169190 DOI: 10.1016/J.Ebiom.2017.01.033  0.34
2017 Hafkenscheid L, Bondt A, Scherer HU, Huizinga TW, Wuhrer M, Toes RE, Rombouts Y. Structural Analysis of Variable Domain Glycosylation of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Reveals the Presence of Highly Sialylated Glycans. Molecular & Cellular Proteomics : McP. 16: 278-287. PMID 27956708 DOI: 10.1074/Mcp.M116.062919  0.459
2017 Reiding KR, Ruhaak LR, Uh HW, El Bouhaddani S, van den Akker EB, Plomp R, McDonnell LA, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Wuhrer M. Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health. Molecular & Cellular Proteomics : McP. 16: 228-242. PMID 27932526 DOI: 10.1074/Mcp.M116.065250  0.388
2017 Sonneveld ME, Koelewijn J, de Haas M, Admiraal J, Plomp R, Koeleman CA, Hipgrave Ederveen AL, Ligthart P, Wuhrer M, van der Schoot CE, Vidarsson G. Antigen specificity determines anti-red blood cell IgG-Fc alloantibody glycosylation and thereby severity of haemolytic disease of the fetus and newborn. British Journal of Haematology. 176: 651-660. PMID 27891581 DOI: 10.1111/Bjh.14438  0.358
2017 Holst S, van Pelt GW, Mesker WE, Tollenaar RA, Belo AI, van Die I, Rombouts Y, Wuhrer M. High-Throughput and High-Sensitivity Mass Spectrometry-Based N-Glycomics of Mammalian Cells. Methods in Molecular Biology (Clifton, N.J.). 1503: 185-196. PMID 27743367 DOI: 10.1007/978-1-4939-6493-2_14  0.363
2017 Stavenhagen K, Hinneburg H, Kolarich D, Wuhrer M. Site-Specific N- and O-Glycopeptide Analysis Using an Integrated C18-PGC-LC-ESI-QTOF-MS/MS Approach. Methods in Molecular Biology (Clifton, N.J.). 1503: 109-119. PMID 27743362 DOI: 10.1007/978-1-4939-6493-2_9  0.37
2017 de Haan N, Reiding KR, Wuhrer M. Sialic Acid Derivatization for the Rapid Subclass- and Sialic Acid Linkage-Specific MALDI-TOF-MS Analysis of IgG Fc-Glycopeptides. Methods in Molecular Biology (Clifton, N.J.). 1503: 49-62. PMID 27743358 DOI: 10.1007/978-1-4939-6493-2_5  0.384
2017 Falck D, Jansen BC, de Haan N, Wuhrer M. High-Throughput Analysis of IgG Fc Glycopeptides by LC-MS. Methods in Molecular Biology (Clifton, N.J.). 1503: 31-47. PMID 27743357 DOI: 10.1007/978-1-4939-6493-2_4  0.439
2017 Delannoy CP, Rombouts Y, Groux-Degroote S, Holst S, Coddeville B, Harduin-Lepers A, Wuhrer M, Elass-Rochard E, Guérardel Y. Glycosylation Changes Triggered by the Differentiation of Monocytic THP-1 Cell Line into Macrophages. Journal of Proteome Research. 16: 156-169. PMID 27351377 DOI: 10.1021/Acs.Jproteome.6B00161  0.373
2017 Bondt A, Hafkenscheid L, Falck D, Kuijper T, Rombouts Y, Hazes J, Wuhrer M, Dolhain R. FRI0083 Reduced increase of ACPA IGG-FC galactosylation during pregnancy in comparison to total IGG: an explanation why autoantibody positive RA-patients improve less during pregnancy? Annals of the Rheumatic Diseases. 76: 509-509. DOI: 10.1136/Annrheumdis-2017-Eular.6229  0.336
2016 Dekkers G, Plomp R, Koeleman CA, Visser R, von Horsten HH, Sandig V, Rispens T, Wuhrer M, Vidarsson G. Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans. Scientific Reports. 6: 36964. PMID 27872474 DOI: 10.1038/Srep36964  0.413
2016 Jansen BC, Bondt A, Reiding KR, Scherjon SA, Vidarsson G, Wuhrer M. MALDI-TOF-MS reveals differential N-linked plasma- and IgG-glycosylation profiles between mothers and their newborns. Scientific Reports. 6: 34001. PMID 27666402 DOI: 10.1038/Srep34001  0.356
2016 Maier M, Reusch D, Bruggink C, Bulau P, Wuhrer M, Mølhøj M. Applying mini-bore HPAEC-MS/MS for the characterization and quantification of Fc N-glycans from heterogeneously glycosylated IgGs. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1033: 342-352. PMID 27614258 DOI: 10.1016/J.Jchromb.2016.08.001  0.402
2016 Kozak RP, Urbanowicz PA, Punyadeera C, Reiding KR, Jansen BC, Royle L, Spencer DI, Fernandes DL, Wuhrer M. Variation of Human Salivary O-Glycome. Plos One. 11: e0162824. PMID 27610614 DOI: 10.1371/Journal.Pone.0162824  0.361
2016 Reiding KR, Hipgrave Ederveen AL, Rombouts Y, Wuhrer M. Murine Plasma N-Glycosylation Traits Associated with Sex and Strain. Journal of Proteome Research. 15: 3489-3499. PMID 27546880 DOI: 10.1021/Acs.Jproteome.6B00071  0.34
2016 Shubhakar A, Kozak RP, Reiding KR, Royle L, Spencer DI, Fernandes DL, Wuhrer M. Automated High-Throughput Permethylation for Glycosylation Analysis of Biologics using MALDI-TOF-MS. Analytical Chemistry. PMID 27479043 DOI: 10.1021/Acs.Analchem.6B01639  0.382
2016 Heijs B, Holst S, Briaire-de Bruijn IH, van Pelt GW, de Ru AH, van Veelen PA, Drake RR, Mehta AS, Mesker WE, Tollenaar RA, Bovee JV, Wuhrer M, McDonnell LA. Multimodal Mass Spectrometry Imaging of N-glycans and Proteins from the Same Tissue Section. Analytical Chemistry. PMID 27373711 DOI: 10.1021/Acs.Analchem.6B01739  0.347
2016 de Jong SE, Selman MH, Adegnika AA, Amoah AS, van Riet E, Kruize YC, Raynes JG, Rodriguez A, Boakye D, von Mutius E, Knulst AC, Genuneit J, Cooper PJ, Hokke CH, Wuhrer M, et al. IgG1 Fc N-glycan galactosylation as a biomarker for immune activation. Scientific Reports. 6: 28207. PMID 27306703 DOI: 10.1038/Srep28207  0.38
2016 Bondt A, Nicolardi S, Jansen BC, Stavenhagen K, Blank D, Kammeijer GS, Kozak RP, Fernandes DL, Hensbergen PJ, Hazes JM, van der Burgt YE, Dolhain RJ, Wuhrer M. Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides. Scientific Reports. 6: 27955. PMID 27302155 DOI: 10.1038/Srep27955  0.394
2016 Jansen BC, Falck D, de Haan N, Hipgrave Ederveen AL, Razdorov G, Lauc G, Wuhrer M. LaCyTools - a targeted LC-MS data processing package for relative quantitation of glycopeptides. Journal of Proteome Research. PMID 27267458 DOI: 10.1021/Acs.Jproteome.6B00171  0.342
2016 Kolarich D, Wuhrer M. Glycomics & Glycoproteomics in Glycoconjugate journal. Glycoconjugate Journal. 33: 259-60. PMID 27178342 DOI: 10.1007/S10719-016-9674-2  0.304
2016 de Haan N, Reiding KR, Driessen G, van der Burg M, Wuhrer M. Changes in Healthy Human IgG Fc-Glycosylation after Birth and during Early Childhood. Journal of Proteome Research. 15: 1853-61. PMID 27161864 DOI: 10.1021/Acs.Jproteome.6B00038  0.432
2016 Holst S, Heijs B, de Haan N, van Zeijl RJ, Briaire-de Bruijn IH, van Pelt GW, Mehta AS, Angel PM, Mesker WE, Tollenaar RA, Drake RR, Bovee JV, McDonnell LA, Wuhrer M. Linkage-specific in-situ sialic acid derivatization for N-glycan mass spectrometry imaging of FFPE tissues. Analytical Chemistry. PMID 27145236 DOI: 10.1021/Acs.Analchem.6B00819  0.365
2016 Kammeijer GS, Kohler I, Jansen BC, Hensbergen PJ, Mayboroda OA, Falck D, Wuhrer M. Dopant enriched nitrogen gas combined with sheathless CE-ESI-MS for improved sensitivity and repeatability in glycopeptide analysis. Analytical Chemistry. PMID 27119460 DOI: 10.1021/Acs.Analchem.6B00479  0.327
2016 Jansen BC, Bondt A, Reiding KR, Lonardi E, de Jong CJ, Falck D, Kammeijer GS, Dolhain RJ, Rombouts Y, Wuhrer M. Pregnancy-associated serum N-glycome changes studied by high-throughput MALDI-TOF-MS. Scientific Reports. 6: 23296. PMID 27075729 DOI: 10.1038/Srep23296  0.347
2016 Sonneveld ME, Natunen S, Sainio S, Koeleman CA, Holst S, Dekkers G, Koelewijn J, Partanen J, van der Schoot CE, Wuhrer M, Vidarsson G. Glycosylation pattern of anti-platelet IgG is stable during pregnancy and predicts clinical outcome in alloimmune thrombocytopenia. British Journal of Haematology. 174: 310-20. PMID 27017954 DOI: 10.1111/Bjh.14053  0.351
2016 Plomp R, Bondt A, de Haan N, Rombouts Y, Wuhrer M. Recent Advances in Clinical Glycoproteomics of Immunoglobulins (Igs). Molecular & Cellular Proteomics : McP. 15: 2217-28. PMID 27009965 DOI: 10.1074/Mcp.O116.058503  0.407
2016 Rombouts Y, Jónasdóttir HS, Hipgrave Ederveen AL, Reiding KR, Jansen BC, Freysdottir J, Hardardottir I, Ioan-Facsinay A, Giera M, Wuhrer M. Acute phase inflammation is characterized by rapid changes in plasma/peritoneal fluid N-glycosylation in mice. Glycoconjugate Journal. PMID 26924641 DOI: 10.1007/S10719-015-9648-9  0.399
2016 Hinneburg H, Stavenhagen K, Schweiger-Hufnagel U, Pengelley S, Jabs W, Seeberger PH, Silva DV, Wuhrer M, Kolarich D. The Art of Destruction: Optimizing Collision Energies in Quadrupole-Time of Flight (Q-TOF) Instruments for Glycopeptide-Based Glycoproteomics. Journal of the American Society For Mass Spectrometry. PMID 26729457 DOI: 10.1007/S13361-015-1308-6  0.366
2016 Reiding KR, Lonardi E, Hipgrave Ederveen AL, Wuhrer M. Ethyl Esterification for MALDI-MS Analysis of Protein Glycosylation. Methods in Molecular Biology (Clifton, N.J.). 1394: 151-162. PMID 26700047 DOI: 10.1007/978-1-4939-3341-9_11  0.385
2016 Sonneveld ME, Haas MD, Koeleman C, Ligthart P, Wuhrer M, Schoot CEVd, Vidarsson G. Patients with Autoimmune Anti-Red Blood Cell IgG1 Have Different Total- and Autoantibody-IgG1 Glycosylation Compared to Healthy Controls Blood. 128: 93-93. DOI: 10.1182/Blood.V128.22.93.93  0.333
2015 Hoffmann M, Marx K, Reichl U, Wuhrer M, Rapp E. Site-specific O-Glycosylation Analysis of Human Blood Plasma Proteins. Molecular & Cellular Proteomics : McP. PMID 26598643 DOI: 10.1074/Mcp.M115.053546  0.337
2015 Jansen BC, Reiding KR, Bondt A, Hipgrave Ederveen AL, Palmblad M, Falck D, Wuhrer M. MassyTools: A High-Throughput Targeted Data Processing Tool for Relative Quantitation and Quality Control Developed for Glycomic and Glycoproteomic MALDI-MS. Journal of Proteome Research. PMID 26565759 DOI: 10.1021/Acs.Jproteome.5B00658  0.3
2015 Clerc F, Reiding KR, Jansen BC, Kammeijer GS, Bondt A, Wuhrer M. Human plasma protein N-glycosylation. Glycoconjugate Journal. PMID 26555091 DOI: 10.1007/S10719-015-9626-2  0.361
2015 Holst S, Deuss AJ, van Pelt GW, van Vliet SJ, Garcia-Vallejo JJ, Koeleman CA, Deelder AM, Mesker WE, Tollenaar RA, Rombouts Y, Wuhrer M. N-glycosylation profiling of colorectal cancer cell lines reveals association of fucosylation with differentiation and CDX1/villin mRNA expression. Molecular & Cellular Proteomics : McP. PMID 26537799 DOI: 10.1074/Mcp.M115.051235  0.336
2015 Stavenhagen K, Plomp R, Wuhrer M. Site-Specific Protein N- and O-Glycosylation Analysis by a C18-Porous Graphitized Carbon-Liquid Chromatography-Electrospray Ionization Mass Spectrometry Approach Using Pronase Treated Glycopeptides. Analytical Chemistry. 87: 11691-9. PMID 26536155 DOI: 10.1021/Acs.Analchem.5B02366  0.401
2015 Meyer S, Nederend M, Jansen JH, Reiding KR, Jacobino SR, Meeldijk J, Bovenschen N, Wuhrer M, Valerius T, Ubink R, Boross P, Rouwendal G, Leusen JH. Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting. Mabs. 0. PMID 26466856 DOI: 10.1080/19420862.2015.1106658  0.351
2015 Fokkink WJ, Falck D, Santbergen TC, Huizinga R, Wuhrer M, Jacobs BC. Comparison of Fc N-Glycosylation of Pharmaceutical Products of Intravenous Immunoglobulin G. Plos One. 10: e0139828. PMID 26457892 DOI: 10.1371/Journal.Pone.0139828  0.333
2015 Rouwendal GJ, van der Lee MM, Meyer S, Reiding KR, Schouten J, de Roo G, Egging DF, Leusen JH, Boross P, Wuhrer M, Verheijden GF, Dokter WH, Timmers M, Ubink R. A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA. Mabs. 0. PMID 26440530 DOI: 10.1080/19420862.2015.1102812  0.399
2015 Borelli V, Vanhooren V, Lonardi E, Reiding KR, Capri M, Libert C, Garagnani P, Salvioli S, Franceschi C, Wuhrer M. Plasma N-Glycome Signature of Down Syndrome. Journal of Proteome Research. 14: 4232-45. PMID 26334954 DOI: 10.1021/Acs.Jproteome.5B00356  0.309
2015 Falck D, Jansen BC, Plomp R, Reusch D, Haberger M, Wuhrer M. Glycoforms of Immunoglobulin G Based Biopharmaceuticals Are Differentially Cleaved by Trypsin Due to the Glycoform Influence on Higher-Order Structure. Journal of Proteome Research. 14: 4019-28. PMID 26244886 DOI: 10.1021/Acs.Jproteome.5B00573  0.395
2015 de Haan N, Reiding KR, Haberger M, Reusch D, Falck D, Wuhrer M. Linkage-specific sialic acid derivatization for MALDI-TOF-MS profiling of IgG glycopeptides. Analytical Chemistry. 87: 8284-91. PMID 26191964 DOI: 10.1021/Acs.Analchem.5B02426  0.441
2015 Bladergroen MR, Reiding KR, Hipgrave Ederveen AL, Vreeker GC, Clerc F, Holst S, Bondt A, Wuhrer M, van der Burgt YE. Automation of High-Throughput Mass Spectrometry-Based Plasma N-Glycome Analysis with Linkage-Specific Sialic Acid Esterification. Journal of Proteome Research. 14: 4080-6. PMID 26179816 DOI: 10.1021/Acs.Jproteome.5B00538  0.379
2015 Krumpochova P, Bruyneel B, Molenaar D, Koukou A, Wuhrer M, Niessen WM, Giera M. Amino acid analysis using chromatography-mass spectrometry: An inter platform comparison study. Journal of Pharmaceutical and Biomedical Analysis. 114: 398-407. PMID 26115383 DOI: 10.1016/J.Jpba.2015.06.001  0.334
2015 Reusch D, Haberger M, Falck D, Peter B, Maier B, Gassner J, Hook M, Wagner K, Bonnington L, Bulau P, Wuhrer M. Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles-Part 2: Mass spectrometric methods. Mabs. 7: 732-42. PMID 25996192 DOI: 10.1080/19420862.2015.1045173  0.394
2015 Smit CH, van Diepen A, Nguyen DL, Wuhrer M, Hoffmann KF, Deelder AM, Hokke CH. Glycomic Analysis of Life Stages of the Human Parasite Schistosoma mansoni Reveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs. Molecular & Cellular Proteomics : McP. 14: 1750-69. PMID 25883177 DOI: 10.1074/Mcp.M115.048280  0.359
2015 Shubhakar A, Reiding KR, Gardner RA, Spencer DI, Fernandes DL, Wuhrer M. High-Throughput Analysis and Automation for Glycomics Studies. Chromatographia. 78: 321-333. PMID 25814696 DOI: 10.1007/S10337-014-2803-9  0.335
2015 Wuhrer M, Stavenhagen K, Koeleman CA, Selman MH, Harper L, Jacobs BC, Savage CO, Jefferis R, Deelder AM, Morgan M. Skewed Fc glycosylation profiles of anti-proteinase 3 immunoglobulin G1 autoantibodies from granulomatosis with polyangiitis patients show low levels of bisection, galactosylation, and sialylation. Journal of Proteome Research. 14: 1657-65. PMID 25761865 DOI: 10.1021/Pr500780A  0.381
2015 Plomp R, Dekkers G, Rombouts Y, Visser R, Koeleman CA, Kammeijer GS, Jansen BC, Rispens T, Hensbergen PJ, Vidarsson G, Wuhrer M. Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3). Molecular & Cellular Proteomics : McP. 14: 1373-84. PMID 25759508 DOI: 10.1074/Mcp.M114.047381  0.407
2015 Holst S, Wuhrer M, Rombouts Y. Glycosylation characteristics of colorectal cancer. Advances in Cancer Research. 126: 203-56. PMID 25727149 DOI: 10.1016/Bs.Acr.2014.11.004  0.376
2015 Rombouts Y, Willemze A, van Beers JJ, Shi J, Kerkman PF, van Toorn L, Janssen GM, Zaldumbide A, Hoeben RC, Pruijn GJ, Deelder AM, Wolbink G, Rispens T, van Veelen PA, Huizinga TW, ... Wuhrer M, et al. Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis. Annals of the Rheumatic Diseases. PMID 25587188 DOI: 10.1136/Annrheumdis-2014-206598  0.349
2015 Reusch D, Haberger M, Maier B, Maier M, Kloseck R, Zimmermann B, Hook M, Szabo Z, Tep S, Wegstein J, Alt N, Bulau P, Wuhrer M. Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles--part 1: separation-based methods. Mabs. 7: 167-79. PMID 25524468 DOI: 10.4161/19420862.2014.986000  0.387
2015 Kapur R, Della Valle L, Verhagen OJ, Hipgrave Ederveen A, Ligthart P, de Haas M, Kumpel B, Wuhrer M, van der Schoot CE, Vidarsson G. Prophylactic anti-D preparations display variable decreases in Fc-fucosylation of anti-D. Transfusion. 55: 553-62. PMID 25234110 DOI: 10.1111/Trf.12880  0.33
2015 Rombouts Y, Ewing E, van de Stadt LA, Selman MH, Trouw LA, Deelder AM, Huizinga TW, Wuhrer M, van Schaardenburg D, Toes RE, Scherer HU. Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis. Annals of the Rheumatic Diseases. 74: 234-41. PMID 24106048 DOI: 10.1136/Annrheumdis-2013-203565  0.37
2015 Wuhrer M, Selman MHJ, McDonnell LA, Kümpfel T, Derfuss T, Khademi M, Olsson T, Hohlfeld R, Meinl E, Krumbholz M. Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid Journal of Neuroinflammation. 12. DOI: 10.1186/S12974-015-0450-1  0.409
2015 Sonneveld ME, Plomp R, Admiraal J, Koeleman C, Hipgrave-Ederveen A, Koelewijn J, Ligthart P, Haas MD, Wuhrer M, Schoot CEVd, Vidarsson G. IgG Alloantibodies Against RBC Induced By Pregnancy or Transfusion Have Unique Glycosylation Patterns Which Correlate with Clinical Outcome of Hemolytic Disease of the Fetus or Newborn Blood. 126: 660-660. DOI: 10.1182/Blood.V126.23.660.660  0.372
2015 Dotz V, Haselberg R, Shubhakar A, Kozak RP, Falck D, Rombouts Y, Reusch D, Somsen GW, Fernandes DL, Wuhrer M. Mass spectrometry for glycosylation analysis of biopharmaceuticals Trac - Trends in Analytical Chemistry. 73: 1-9. DOI: 10.1016/J.Trac.2015.04.024  0.347
2014 Stavenhagen K, Kolarich D, Wuhrer M. Clinical Glycomics Employing Graphitized Carbon Liquid Chromatography-Mass Spectrometry. Chromatographia. 78: 307-320. PMID 25750456 DOI: 10.1007/S10337-014-2813-7  0.399
2014 Fokkink WJ, Selman MH, Wuhrer M, Jacobs BC. Immunoglobulin G Fc N-glycosylation in Guillain-Barré syndrome treated with intravenous immunoglobulin. Clinical and Experimental Immunology. 178: 105-7. PMID 25546781 DOI: 10.1111/Cei.12530  0.438
2014 Gardinassi LG, Dotz V, Hipgrave Ederveen A, de Almeida RP, Nery Costa CH, Costa DL, de Jesus AR, Mayboroda OA, Garcia GR, Wuhrer M, de Miranda Santos IK. Clinical severity of visceral leishmaniasis is associated with changes in immunoglobulin g fc N-glycosylation. Mbio. 5: e01844. PMID 25467439 DOI: 10.1128/Mbio.01844-14  0.426
2014 Nagelkerke SQ, Dekkers G, Kustiawan I, van de Bovenkamp FS, Geissler J, Plomp R, Wuhrer M, Vidarsson G, Rispens T, van den Berg TK, Kuijpers TW. Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages. Blood. 124: 3709-18. PMID 25352126 DOI: 10.1182/Blood-2014-05-576835  0.349
2014 Bondt A, Rombouts Y, Selman MH, Hensbergen PJ, Reiding KR, Hazes JM, Dolhain RJ, Wuhrer M. Immunoglobulin G (IgG) Fab glycosylation analysis using a new mass spectrometric high-throughput profiling method reveals pregnancy-associated changes. Molecular & Cellular Proteomics : McP. 13: 3029-39. PMID 25004930 DOI: 10.1074/Mcp.M114.039537  0.439
2014 Theodoratou E, Campbell H, Ventham NT, Kolarich D, Pu?i?-Bakovi? M, Zoldoš V, Fernandes D, Pemberton IK, Rudan I, Kennedy NA, Wuhrer M, Nimmo E, Annese V, McGovern DP, Satsangi J, et al. The role of glycosylation in IBD. Nature Reviews. Gastroenterology & Hepatology. 11: 588-600. PMID 24912389 DOI: 10.1038/Nrgastro.2014.78  0.325
2014 Kapur R, Della Valle L, Sonneveld M, Hipgrave Ederveen A, Visser R, Ligthart P, de Haas M, Wuhrer M, van der Schoot CE, Vidarsson G. Low anti-RhD IgG-Fc-fucosylation in pregnancy: a new variable predicting severity in haemolytic disease of the fetus and newborn. British Journal of Haematology. 166: 936-45. PMID 24909983 DOI: 10.1111/Bjh.12965  0.395
2014 Reiding KR, Blank D, Kuijper DM, Deelder AM, Wuhrer M. High-throughput profiling of protein N-glycosylation by MALDI-TOF-MS employing linkage-specific sialic acid esterification. Analytical Chemistry. 86: 5784-93. PMID 24831253 DOI: 10.1021/Ac500335T  0.398
2014 Huffman JE, Pučić-Baković M, Klarić L, Hennig R, Selman MH, Vučković F, Novokmet M, KriÅ¡tić J, Borowiak M, Muth T, PolaÅ¡ek O, Razdorov G, Gornik O, Plomp R, Theodoratou E, ... ... Wuhrer M, et al. Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research. Molecular & Cellular Proteomics : McP. 13: 1598-610. PMID 24719452 DOI: 10.1074/Mcp.M113.037465  0.351
2014 Fokkink WR, Selman MHJ, Dortland JR, Durmuş B, Kuitwaard K, Huizinga R, Rijs Wv, Tio-Gillen AP, Doorn PAv, Deelder AM, Wuhrer M, Jacobs BC. IgG Fc N-glycosylation in Guillain-Barré syndrome treated with immunoglobulins. Journal of Proteome Research. 13: 1722-1730. PMID 24533874 DOI: 10.1021/Pr401213Z  0.4
2014 Ruhaak LR, Uh HW, Deelder AM, Dolhain RE, Wuhrer M. Total plasma N-glycome changes during pregnancy. Journal of Proteome Research. 13: 1657-68. PMID 24527664 DOI: 10.1021/Pr401128J  0.304
2014 Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CAM, Deelder AM, Wuhrer M. Site-specific N-glycosylation analysis of human immunoglobulin e Journal of Proteome Research. 13: 536-546. PMID 24308486 DOI: 10.1021/Pr400714W  0.423
2014 Kapur R, Kustiawan I, Vestrheim A, Koeleman CA, Visser R, Einarsdottir HK, Porcelijn L, Jackson D, Kumpel B, Deelder AM, Blank D, Skogen B, Killie MK, Michaelsen TE, de Haas M, ... ... Wuhrer M, et al. A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy. Blood. 123: 471-80. PMID 24243971 DOI: 10.1182/Blood-2013-09-527978  0.39
2014 Reusch D, Haberger M, Kailich T, Heidenreich AK, Kampe M, Bulau P, Wuhrer M. High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer. Mabs. 6: 185-96. PMID 24135630 DOI: 10.4161/Mabs.26712  0.413
2014 Scherer HU, Rombouts Y, Willemze A, Beers Jv, Shi J, Kerkman P, Janssen G, Veelen Pv, Zaldumbide A, Hoeben R, Pruijn G, Deelder A, Wolbink G-, Rispens T, Huizinga TW, ... Wuhrer M, et al. OP0177 A High Frequency of N-Glycans in the Acpa-Igg Variable Domain Modulates Reactivity to Citrullinated Antigens Annals of the Rheumatic Diseases. 73: 129-129. DOI: 10.1136/Annrheumdis-2014-Eular.4717  0.416
2014 Rombouts Y, Willemze A, Beers JJBCv, Shi J, Kerkman PF, Janssen GMC, Veelen PAv, Zaldumbide A, Hoeben RC, Pruijn GJ, Deelder AM, Wolbink G, Rispens T, García-Vallejo JJ, Kooyk Yv, ... ... Wuhrer M, et al. A1.45 Hyperglycosylation of ACPA-IGG variable domains modulates reactivity to citrullinated antigens Annals of the Rheumatic Diseases. 73. DOI: 10.1136/Annrheumdis-2013-205124.44  0.434
2014 Bondt A, Rombouts Y, Hazes JMW, Wuhrer M, Dolhain RJEM. A1.2 High Throughput analysis of IGG fab glycosylation reveals differences between RA-patients and healthy controls during pregnancy and after delivery Annals of the Rheumatic Diseases. 73: A1.2-A1. DOI: 10.1136/Annrheumdis-2013-205124.2  0.342
2014 Giera M, Wuhrer M. Recent Developments in Clinical Omics Chromatographia. 78: 305-306. DOI: 10.1007/S10337-014-2805-7  0.321
2013 Ruhaak LR, Koeleman CA, Uh HW, Stam JC, van Heemst D, Maier AB, Houwing-Duistermaat JJ, Hensbergen PJ, Slagboom PE, Deelder AM, Wuhrer M. Targeted biomarker discovery by high throughput glycosylation profiling of human plasma alpha1-antitrypsin and immunoglobulin A. Plos One. 8: e73082. PMID 24039863 DOI: 10.1371/Journal.Pone.0073082  0.366
2013 Bondt A, Selman MH, Deelder AM, Hazes JM, Willemsen SP, Wuhrer M, Dolhain RJ. Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation. Journal of Proteome Research. 12: 4522-31. PMID 24016253 DOI: 10.1021/Pr400589M  0.323
2013 Holst S, Stavenhagen K, Balog CIA, Koeleman CAM, McDonnell LM, Mayboroda OA, Verhoeven A, Mesker WE, Tollenaar RAEM, Deelder AM, Wuhrer M. Investigations on aberrant glycosylation of glycosphingolipids in colorectal cancer tissues using liquid chromatography and matrix-assisted laser desorption time-of- flight mass spectrometry (MALDI-TOF-MS) Molecular and Cellular Proteomics. 12: 3081-3093. PMID 23878401 DOI: 10.1074/Mcp.M113.030387  0.327
2013 Leymarie N, Griffin PJ, Jonscher K, Kolarich D, Orlando R, McComb M, Zaia J, Aguilan J, Alley WR, Altmann F, Ball LE, Basumallick L, Bazemore-Walker CR, Behnken H, Blank MA, ... ... Wuhrer M, et al. Interlaboratory study on differential analysis of protein glycosylation by mass spectrometry: the ABRF glycoprotein research multi-institutional study 2012. Molecular & Cellular Proteomics : McP. 12: 2935-51. PMID 23764502 DOI: 10.1074/Mcp.M113.030643  0.383
2013 Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, Novokmet M, PolaÅ¡ek O, Gornik O, KriÅ¡tić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, ... ... Wuhrer M, et al. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. Plos Genetics. 9: e1003225. PMID 23382691 DOI: 10.1371/Journal.Pgen.1003225  0.419
2013 Nicolardi S, van der Burgt YE, Wuhrer M, Deelder AM. Mapping O-glycosylation of apolipoprotein C-III in MALDI-FT-ICR protein profiles. Proteomics. 13: 992-1001. PMID 23335445 DOI: 10.1002/Pmic.201200293  0.352
2013 Zauner G, Selman MH, Bondt A, Rombouts Y, Blank D, Deelder AM, Wuhrer M. Glycoproteomic analysis of antibodies. Molecular & Cellular Proteomics : McP. 12: 856-65. PMID 23325769 DOI: 10.1074/Mcp.R112.026005  0.452
2013 Baković MP, Selman MH, Hoffmann M, Rudan I, Campbell H, Deelder AM, Lauc G, Wuhrer M. High-throughput IgG Fc N-glycosylation profiling by mass spectrometry of glycopeptides. Journal of Proteome Research. 12: 821-31. PMID 23298168 DOI: 10.1021/Pr300887Z  0.389
2013 Zauner G, Koeleman CA, Deelder AM, Wuhrer M. Nano-HPLC-MS of glycopeptides obtained after nonspecific proteolysis. Methods in Molecular Biology (Clifton, N.J.). 951: 113-27. PMID 23296528 DOI: 10.1007/978-1-62703-146-2_9  0.366
2013 Heemskerk AA, Wuhrer M, Busnel JM, Koeleman CA, Selman MH, Vidarsson G, Kapur R, Schoenmaker B, Derks RJ, Deelder AM, Mayboroda OA. Coupling porous sheathless interface MS with transient-ITP in neutral capillaries for improved sensitivity in glycopeptide analysis. Electrophoresis. 34: 383-7. PMID 23161657 DOI: 10.1002/Elps.201200357  0.431
2013 Reusch D, Haberger M, Selman MH, Bulau P, Deelder AM, Wuhrer M, Engler N. High-throughput work flow for IgG Fc-glycosylation analysis of biotechnological samples. Analytical Biochemistry. 432: 82-9. PMID 23026777 DOI: 10.1016/J.Ab.2012.09.032  0.417
2013 Einarsdottir HK, Selman MH, Kapur R, Scherjon S, Koeleman CA, Deelder AM, van der Schoot CE, Vidarsson G, Wuhrer M. Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G. Glycoconjugate Journal. 30: 147-57. PMID 22572841 DOI: 10.1007/S10719-012-9381-6  0.381
2013 Dall’Olio F, Vanhooren V, Chen CC, Slagboom PE, Wuhrer M, Franceschi C. N-glycomic biomarkers of biological aging and longevity: a link with inflammaging. Ageing Research Reviews. 12: 685-698. PMID 22353383 DOI: 10.1016/J.Arr.2012.02.002  0.373
2013 Scherer HU, Rombouts Y, Ewing E, Stadt LAvd, Selman MH, Deelder AM, Huizinga TW, Wuhrer M, Schaardenburg Dv, Toes RE. OP0189 Anti-Citrullinated Protein Antibody Specific FC Glycosylation Patterns in Patients with Arthralgia Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-Eular.394  0.394
2013 Kempers A, Scherer H, Rombouts Y, Ewing E, Stadt Lvd, Selman M, Deelder A, Huizinga T, Wuhrer M, Schaardenburg Dv, Toes R. A1.1 Anti-Citrullinated Protein Antibody Specific Fc Glycosylation Patterns in Arthralgia Patients Annals of the Rheumatic Diseases. 72. DOI: 10.1136/Annrheumdis-2013-203214.1  0.382
2013 Wang J, Balog CI, Stavenhagen K, Koeleman CA, Selman MH, Deelder AM, Huizinga TW, Toes RE, Wuhrer M, Scherer HU. FRI0004 Modulating FC-linked glycosylation patterns of human IGG1 Annals of the Rheumatic Diseases. 71: 312-312. DOI: 10.1136/Annrheumdis-2012-Eular.2461  0.392
2013 Morgan M, Stavenhagen K, Koeleman C, Hipgrave-Ederveen A, Harper L, Jacobs B, Savage C, Jefferis R, Deelder A, Wuhrer M. Galactosylation and sialylation of anti-proteinase 3 antibodies in granulomatosis with polyangiitis is associated with increased inflammatory cytokines La Presse MéDicale. 42: 761. DOI: 10.1016/J.Lpm.2013.02.259  0.317
2012 Zauner G, Hoffmann M, Rapp E, Koeleman CAM, Dragan I, Deelder AM, Wuhrer M, Hensbergen PJ. Glycoproteomic analysis of human fibrinogen reveals novel regions of O-glycosylation Journal of Proteome Research. 11: 5804-5814. PMID 23050552 DOI: 10.1021/Pr3005937  0.391
2012 Ruhaak LR, Huhn C, Koeleman CA, Deelder AM, Wuhrer M. Robust and high-throughput sample preparation for (semi-)quantitative analysis of N-glycosylation profiles from plasma samples. Methods in Molecular Biology (Clifton, N.J.). 893: 371-85. PMID 22665312 DOI: 10.1007/978-1-61779-885-6_23  0.331
2012 Balog CIA, Stavenhagen K, Fung WLJ, Koeleman CA, McDonnell LA, Verhoeven A, Mesker WE, Tollenaar RAEM, Deelder AM, Wuhrer M. N-glycosylation of colorectal cancer tissues: A liquid chromatography and mass spectrometry-based investigation Molecular and Cellular Proteomics. 11: 571-585. PMID 22573871 DOI: 10.1074/Mcp.M111.011601  0.382
2012 Wuhrer M. Glycomics using mass spectrometry. Glycoconjugate Journal. 30: 11-22. PMID 22532006 DOI: 10.1007/S10719-012-9376-3  0.346
2012 Bruggink C, Poorthuis BJ, Deelder AM, Wuhrer M. Analysis of urinary oligosaccharides in lysosomal storage disorders by capillary high-performance anion-exchange chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry. 403: 1671-83. PMID 22526647 DOI: 10.1007/S00216-012-5968-9  0.333
2012 Huhn C, Ruhaak LR, Mannhardt J, Wuhrer M, Neusüß C, Deelder AM, Meyer H. Alignment of laser-induced fluorescence and mass spectrometric detection traces using electrophoretic mobility scaling in CE-LIF-MS of labeled N-glycans. Electrophoresis. 33: 563-6. PMID 22451048 DOI: 10.1002/Elps.201100367  0.332
2012 Carlsson MC, Balog CI, Kilsgård O, Hellmark T, Bakoush O, Segelmark M, Fernö M, Olsson H, Malmström J, Wuhrer M, Leffler H. Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease. Biochimica Et Biophysica Acta. 1820: 1366-72. PMID 22285770 DOI: 10.1016/J.Bbagen.2012.01.007  0.323
2012 Zauner G, Deelder AM, Wuhrer M. Recent advances in hydrophilic interaction liquid chromatography (HILIC) for structural glycomics. Electrophoresis. 32: 3456-66. PMID 22180202 DOI: 10.1002/Elps.201100247  0.35
2012 Selman MH, Derks RJ, Bondt A, Palmblad M, Schoenmaker B, Koeleman CA, van de Geijn FE, Dolhain RJ, Deelder AM, Wuhrer M. Fc specific IgG glycosylation profiling by robust nano-reverse phase HPLC-MS using a sheath-flow ESI sprayer interface. Journal of Proteomics. 75: 1318-29. PMID 22120122 DOI: 10.1016/J.Jprot.2011.11.003  0.436
2012 Lonardi E, Deelder AM, Wuhrer M, Balog CI. Microarray technology using glycans extracted from natural sources for serum antibody fluorescent detection. Methods in Molecular Biology (Clifton, N.J.). 808: 285-302. PMID 22057533 DOI: 10.1007/978-1-61779-373-8_20  0.371
2012 Kapur R, Vestrheim A, Koeleman CA, Porcelijn L, Jackson D, Kumpel B, Deelder AM, Michaelsen TE, Haas Md, Schoot CEVd, Wuhrer M, Vidarsson G. Skewing towards Decreased Fc-Fucosylation of Platelet-Alloantibodies in Pregnancy Blood. 120: 3331-3331. DOI: 10.1182/Blood.V120.21.3331.3331  0.404
2012 Bondt A, Selman MHJ, Hazes JMW, Deelder AM, Wuhrer M, Dolhain RJEM. Changes in IgG-Fc N-glycan sialylation, galactosylation and fucosylation influence disease activity during and after pregnancy in rheumatoid arthritis Annals of the Rheumatic Diseases. 71: A34.2-A35. DOI: 10.1136/Annrheumdis-2011-201234.7  0.313
2011 Selman MH, de Jong SE, Soonawala D, Kroon FP, Adegnika AA, Deelder AM, Hokke CH, Yazdanbakhsh M, Wuhrer M. Changes in antigen-specific IgG1 Fc N-glycosylation upon influenza and tetanus vaccination. Molecular & Cellular Proteomics : McP. 11: M111.014563. PMID 22184099 DOI: 10.1074/Mcp.M111.014563  0.369
2011 Huhn C, Ruhaak LR, Wuhrer M, Deelder AM. Hexapeptide library as a universal tool for sample preparation in protein glycosylation analysis. Journal of Proteomics. 75: 1515-28. PMID 22154983 DOI: 10.1016/J.Jprot.2011.11.028  0.33
2011 Pacchiarotta T, Hensbergen PJ, Wuhrer M, van Nieuwkoop C, Nevedomskaya E, Derks RJ, Schoenmaker B, Koeleman CA, van Dissel J, Deelder AM, Mayboroda OA. Fibrinogen alpha chain O-glycopeptides as possible markers of urinary tract infection. Journal of Proteomics. 75: 1067-73. PMID 22075168 DOI: 10.1016/J.Jprot.2011.10.021  0.369
2011 Carlsson MC, Cederfur C, Schaar V, Balog CI, Lepur A, Touret F, Salomonsson E, Deelder AM, Fernö M, Olsson H, Wuhrer M, Leffler H. Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients. Plos One. 6: e26560. PMID 22028908 DOI: 10.1371/Journal.Pone.0026560  0.324
2011 Huffman JE, Knezevic A, Vitart V, Kattla J, Adamczyk B, Novokmet M, Igl W, Pucic M, Zgaga L, Johannson Ã…, Redzic I, Gornik O, Zemunik T, Polasek O, Kolcic I, ... ... Wuhrer M, et al. Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults. Human Molecular Genetics. 20: 5000-11. PMID 21908519 DOI: 10.1093/Hmg/Ddr414  0.316
2011 Zauner G, Koeleman CA, Deelder AM, Wuhrer M. Mass spectrometric O-glycan analysis after combined O-glycan release by beta-elimination and 1-phenyl-3-methyl-5-pyrazolone labeling. Biochimica Et Biophysica Acta. 1820: 1420-8. PMID 21803123 DOI: 10.1016/J.Bbagen.2011.07.004  0.32
2011 Guhr T, Bloem J, Derksen NI, Wuhrer M, Koenderman AH, Aalberse RC, Rispens T. Enrichment of sialylated IgG by lectin fractionation does not enhance the efficacy of immunoglobulin G in a murine model of immune thrombocytopenia. Plos One. 6: e21246. PMID 21731683 DOI: 10.1371/Journal.Pone.0021246  0.366
2011 Pucić M, Knezević A, Vidic J, Adamczyk B, Novokmet M, Polasek O, Gornik O, Supraha-Goreta S, Wormald MR, Redzić I, Campbell H, Wright A, Hastie ND, Wilson JF, Rudan I, ... Wuhrer M, et al. High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. Molecular & Cellular Proteomics : McP. 10: M111.010090. PMID 21653738 DOI: 10.1074/Mcp.M111.010090  0.434
2011 Wuhrer M, Deelder AM, van der Burgt YE. Mass spectrometric glycan rearrangements. Mass Spectrometry Reviews. 30: 664-80. PMID 21560141 DOI: 10.1002/Mas.20337  0.329
2011 Wang J, Balog CI, Stavenhagen K, Koeleman CA, Scherer HU, Selman MH, Deelder AM, Huizinga TW, Toes RE, Wuhrer M. Fc-glycosylation of IgG1 is modulated by B-cell stimuli. Molecular & Cellular Proteomics : McP. 10: M110.004655. PMID 21372248 DOI: 10.1074/Mcp.M110.004655  0.413
2011 Meevissen MH, Balog CI, Koeleman CA, Doenhoff MJ, Schramm G, Haas H, Deelder AM, Wuhrer M, Hokke CH. Targeted glycoproteomic analysis reveals that kappa-5 is a major, uniquely glycosylated component of Schistosoma mansoni egg antigens. Molecular & Cellular Proteomics : McP. 10: M110.005710. PMID 21372247 DOI: 10.1074/Mcp.M110.005710  0.42
2011 Selman MH, Hemayatkar M, Deelder AM, Wuhrer M. Cotton HILIC SPE microtips for microscale purification and enrichment of glycans and glycopeptides. Analytical Chemistry. 83: 2492-9. PMID 21366235 DOI: 10.1021/Ac1027116  0.407
2011 Ruhaak LR, Uh HW, Beekman M, Hokke CH, Westendorp RG, Houwing-Duistermaat J, Wuhrer M, Deelder AM, Slagboom PE. Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health. Journal of Proteome Research. 10: 1667-74. PMID 21184610 DOI: 10.1021/Pr1009959  0.306
2011 Lonardi E, Balog CI, Deelder AM, Wuhrer M. Natural glycan microarrays. Expert Review of Proteomics. 7: 761-74. PMID 20973647 DOI: 10.1586/Epr.10.41  0.367
2011 Wang J, Bax M, Balog CIA, Stavenhagen K, Koeleman CAM, Scherer HU, Deelder AM, Huizinga TWJ, Toes REM, Wuhrer M. Fc-glycosylation of IgG1 is modulated by B cell Stimuli Annals of the Rheumatic Diseases. 70: A61-A61. DOI: 10.1136/Ard.2010.149005.10  0.407
2010 Ruhaak LR, Hennig R, Huhn C, Borowiak M, Dolhain RJ, Deelder AM, Rapp E, Wuhrer M. Optimized workflow for preparation of APTS-labeled N-glycans allowing high-throughput analysis of human plasma glycomes using 48-channel multiplexed CGE-LIF. Journal of Proteome Research. 9: 6655-64. PMID 20886907 DOI: 10.1021/Pr100802F  0.352
2010 Ruhaak LR, Uh HW, Beekman M, Koeleman CA, Hokke CH, Westendorp RG, Wuhrer M, Houwing-Duistermaat JJ, Slagboom PE, Deelder AM. Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity. Plos One. 5: e12566. PMID 20830288 DOI: 10.1371/Journal.Pone.0012566  0.316
2010 Selman MH, Niks EH, Titulaer MJ, Verschuuren JJ, Wuhrer M, Deelder AM. IgG fc N-glycosylation changes in Lambert-Eaton myasthenic syndrome and myasthenia gravis. Journal of Proteome Research. 10: 143-52. PMID 20672848 DOI: 10.1021/Pr1004373  0.421
2010 Wuhrer M, van Remoortere A, Balog CI, Deelder AM, Hokke CH. Ligand identification of carbohydrate-binding proteins employing a biotinylated glycan binding assay and tandem mass spectrometry. Analytical Biochemistry. 406: 132-40. PMID 20638358 DOI: 10.1016/J.Ab.2010.07.008  0.359
2010 Bruggink C, Poorthuis BJ, Piraud M, Froissart R, Deelder AM, Wuhrer M. Glycan profiling of urine, amniotic fluid and ascitic fluid from galactosialidosis patients reveals novel oligosaccharides with reducing end hexose and aldohexonic acid residues. The Febs Journal. 277: 2970-86. PMID 20546307 DOI: 10.1111/J.1742-4658.2010.07707.X  0.362
2010 Ruhaak LR, Steenvoorden E, Koeleman CA, Deelder AM, Wuhrer M. 2-picoline-borane: a non-toxic reducing agent for oligosaccharide labeling by reductive amination. Proteomics. 10: 2330-6. PMID 20391534 DOI: 10.1002/Pmic.200900804  0.305
2010 Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K, Olson WC, Berkhout B, Hokke CH, Moore JP, Sanders RW. Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function Virology. 401: 236-247. PMID 20304457 DOI: 10.1016/J.Virol.2010.02.019  0.348
2010 Ruhaak LR, Zauner G, Huhn C, Bruggink C, Deelder AM, Wuhrer M. Glycan labeling strategies and their use in identification and quantification. Analytical and Bioanalytical Chemistry. 397: 3457-81. PMID 20225063 DOI: 10.1007/S00216-010-3532-Z  0.368
2010 Zauner G, Koeleman CA, Deelder AM, Wuhrer M. Protein glycosylation analysis by HILIC-LC-MS of Proteinase K-generated N- and O-glycopeptides. Journal of Separation Science. 33: 903-10. PMID 20222081 DOI: 10.1002/Jssc.200900850  0.397
2010 Meevissen MH, Wuhrer M, Doenhoff MJ, Schramm G, Haas H, Deelder AM, Hokke CH. Structural characterization of glycans on omega-1, a major Schistosoma mansoni egg glycoprotein that drives Th2 responses. Journal of Proteome Research. 9: 2630-42. PMID 20178377 DOI: 10.1021/Pr100081C  0.392
2010 Scherer HU, van der Woude D, Ioan-Facsinay A, el Bannoudi H, Trouw LA, Wang J, Häupl T, Burmester GR, Deelder AM, Huizinga TW, Wuhrer M, Toes RE. Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid. Arthritis and Rheumatism. 62: 1620-9. PMID 20178128 DOI: 10.1002/Art.27414  0.421
2010 Balog CI, Mayboroda OA, Wuhrer M, Hokke CH, Deelder AM, Hensbergen PJ. Mass spectrometric identification of aberrantly glycosylated human apolipoprotein C-III peptides in urine from Schistosoma mansoni-infected individuals. Molecular & Cellular Proteomics : McP. 9: 667-81. PMID 20071361 DOI: 10.1074/Mcp.M900537-Mcp200  0.317
2010 Selman MHJ, McDonnell LA, Palmblad M, Ruhaak RL, Deelder AM, Wuhrer M. Immunoglobulin G glycopeptide profiling by matrix-assisted laser desorption Ionization fourier transform Ion cyclotron resonance mass spectrometry Analytical Chemistry. 82: 1073-1081. PMID 20058878 DOI: 10.1021/Ac9024413  0.418
2009 Huhn C, Ramautar R, Wuhrer M, Somsen GW. Relevance and use of capillary coatings in capillary electrophoresis-mass spectrometry. Analytical and Bioanalytical Chemistry. 396: 297-314. PMID 19838682 DOI: 10.1007/S00216-009-3193-Y  0.316
2009 Schramm G, Hamilton JV, Balog CI, Wuhrer M, Gronow A, Beckmann S, Wippersteg V, Grevelding CG, Goldmann T, Weber E, Brattig NW, Deelder AM, Dunne DW, Hokke CH, Haas H, et al. Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs. Molecular and Biochemical Parasitology. 166: 4-14. PMID 19428667 DOI: 10.1016/J.Molbiopara.2009.02.003  0.37
2009 Wuhrer M, Koeleman CA, Deelder AM. Hexose rearrangements upon fragmentation of N-glycopeptides and reductively aminated N-glycans. Analytical Chemistry. 81: 4422-32. PMID 19419147 DOI: 10.1021/Ac900278Q  0.4
2009 Wuhrer M, Koeleman CA, Deelder AM. Two-dimensional HPLC separation with reverse-phase-nano-LC-MS/MS for the characterization of glycan pools after labeling with 2-aminobenzamide. Methods in Molecular Biology (Clifton, N.J.). 534: 79-91. PMID 19277534 DOI: 10.1007/978-1-59745-022-5_6  0.391
2009 Ruhaak LR, Deelder AM, Wuhrer M. Oligosaccharide analysis by graphitized carbon liquid chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry. 394: 163-74. PMID 19247642 DOI: 10.1007/S00216-009-2664-5  0.364
2009 Huhn C, Selman MH, Ruhaak LR, Deelder AM, Wuhrer M. IgG glycosylation analysis. Proteomics. 9: 882-913. PMID 19212958 DOI: 10.1002/Pmic.200800715  0.479
2009 Wuhrer M, de Boer AR, Deelder AM. Structural glycomics using hydrophilic interaction chromatography (HILIC) with mass spectrometry. Mass Spectrometry Reviews. 28: 192-206. PMID 18979527 DOI: 10.1002/Mas.20195  0.342
2009 Wuhrer M, Porcelijn L, Kapur R, Koeleman CA, Deelder A, de Haas M, Vidarsson G. Regulated glycosylation patterns of IgG during alloimmune responses against human platelet antigens. Journal of Proteome Research. 8: 450-6. PMID 18942870 DOI: 10.1021/Pr800651J  0.418
2008 Scherer HU, Wang J, Toes RE, van der Woude D, Koeleman CA, de Boer AR, Huizinga TW, Deelder AM, Wuhrer M. Immunoglobulin 1 (IgG1) Fc-glycosylation profiling of anti-citrullinated peptide antibodies from human serum. Proteomics. Clinical Applications. 3: 106-15. PMID 21136940 DOI: 10.1002/Prca.200800098  0.373
2008 van Alphen LB, Wuhrer M, Bleumink-Pluym NM, Hensbergen PJ, Deelder AM, van Putten JP. A functional Campylobacter jejuni maf4 gene results in novel glycoforms on flagellin and altered autoagglutination behaviour. Microbiology (Reading, England). 154: 3385-97. PMID 18957592 DOI: 10.1099/Mic.0.2008/019919-0  0.337
2008 Ruhaak LR, Huhn C, Waterreus WJ, de Boer AR, Neusüss C, Hokke CH, Deelder AM, Wuhrer M. Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins. Analytical Chemistry. 80: 6119-26. PMID 18593198 DOI: 10.1021/Ac800630X  0.401
2008 de Boer AR, Hokke CH, Deelder AM, Wuhrer M. Serum antibody screening by surface plasmon resonance using a natural glycan microarray. Glycoconjugate Journal. 25: 75-84. PMID 18193481 DOI: 10.1007/S10719-007-9100-X  0.386
2007 Wuhrer M, Stam JC, van de Geijn FE, Koeleman CA, Verrips CT, Dolhain RJ, Hokke CH, Deelder AM. Glycosylation profiling of immunoglobulin G (IgG) subclasses from human serum. Proteomics. 7: 4070-81. PMID 17994628 DOI: 10.1002/Pmic.200700289  0.462
2007 de Boer AR, Hokke CH, Deelder AM, Wuhrer M. General microarray technique for immobilization and screening of natural glycans. Analytical Chemistry. 79: 8107-13. PMID 17922555 DOI: 10.1021/Ac071187G  0.358
2007 Catalina MI, Koeleman CA, Deelder AM, Wuhrer M. Electron transfer dissociation of N-glycopeptides: loss of the entire N-glycosylated asparagine side chain. Rapid Communications in Mass Spectrometry : Rcm. 21: 1053-61. PMID 17311219 DOI: 10.1002/Rcm.2929  0.383
2007 Robijn ML, Koeleman CA, Wuhrer M, Royle L, Geyer R, Dwek RA, Rudd PM, Deelder AM, Hokke CH. Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody. Molecular and Biochemical Parasitology. 151: 148-61. PMID 17188765 DOI: 10.1016/J.Molbiopara.2006.10.019  0.638
2007 Rouwendal GJA, Wuhrer M, Florack DEA, Koeleman CAM, Deelder AM, Bakker H, Stoopen GM, van Die I, Helsper JPFG, Hokke CH, Bosch D. Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III Glycobiology. 17: 334-344. PMID 17179169 DOI: 10.1093/Glycob/Cwl078  0.391
2007 Wuhrer M, Koeleman CA, Hokke CH, Deelder AM. Mass spectrometry of proton adducts of fucosylated N-glycans: fucose transfer between antennae gives rise to misleading fragments. Rapid Communications in Mass Spectrometry : Rcm. 20: 1747-54. PMID 16676317 DOI: 10.1002/Rcm.2509  0.358
2007 Wuhrer M, Deelder AM. Negative-mode MALDI-TOF/TOF-MS of oligosaccharides labeled with 2-aminobenzamide. Analytical Chemistry. 77: 6954-9. PMID 16255595 DOI: 10.1021/Ac051117E  0.366
2006 Wuhrer M, Catalina MI, Deelder AM, Hokke CH. Glycoproteomics based on tandem mass spectrometry of glycopeptides. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 849: 115-28. PMID 17049937 DOI: 10.1016/J.Jchromb.2006.09.041  0.375
2006 van Riet E, Wuhrer M, Wahyuni S, Retra K, Deelder AM, Tielens AG, van der Kleij D, Yazdanbakhsh M. Antibody responses to Ascaris-derived proteins and glycolipids: the role of phosphorylcholine. Parasite Immunology. 28: 363-71. PMID 16879308 DOI: 10.1111/J.1365-3024.2006.00844.X  0.37
2006 Wuhrer M, Koeleman CA, Fitzpatrick JM, Hoffmann KF, Deelder AM, Hokke CH. Gender-specific expression of complex-type N-glycans in schistosomes. Glycobiology. 16: 991-1006. PMID 16825488 DOI: 10.1093/Glycob/Cwl020  0.315
2006 Wuhrer M, Balog CI, Catalina MI, Jones FM, Schramm G, Haas H, Doenhoff MJ, Dunne DW, Deelder AM, Hokke CH. IPSE/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core-difucosylated N-glycans. The Febs Journal. 273: 2276-92. PMID 16650003 DOI: 10.1111/J.1742-4658.2006.05242.X  0.388
2006 Wuhrer M, Deelder AM. Matrix-assisted laser desorption/ionization in-source decay combined with tandem time-of-flight mass spectrometry of permethylated oligosaccharides: targeted characterization of specific parts of the glycan structure. Rapid Communications in Mass Spectrometry : Rcm. 20: 943-51. PMID 16470682 DOI: 10.1002/Rcm.2390  0.38
2006 Wuhrer M, Koeleman CA, Deelder AM, Hokke CH. Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni. The Febs Journal. 273: 347-61. PMID 16403022 DOI: 10.1111/J.1742-4658.2005.05068.X  0.329
2005 Bruggink C, Wuhrer M, Koeleman CA, Barreto V, Liu Y, Pohl C, Ingendoh A, Hokke CH, Deelder AM. Oligosaccharide analysis by capillary-scale high-pH anion-exchange chromatography with on-line ion-trap mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 829: 136-43. PMID 16246644 DOI: 10.1016/J.Jchromb.2005.10.006  0.348
2005 Wuhrer M, Deelder AM, Hokke CH. Protein glycosylation analysis by liquid chromatography-mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 825: 124-33. PMID 16213446 DOI: 10.1016/J.Jchromb.2005.01.030  0.361
2005 Geyer H, Wuhrer M, Resemann A, Geyer R. Identification and characterization of keyhole limpet hemocyanin N-glycans mediating cross-reactivity with Schistosoma mansoni. The Journal of Biological Chemistry. 280: 40731-48. PMID 16135511 DOI: 10.1074/Jbc.M505985200  0.601
2005 Wuhrer M, Balog CI, Koeleman CA, Deelder AM, Hokke CH. New features of site-specific horseradish peroxidase (HRP) glycosylation uncovered by nano-LC-MS with repeated ion-isolation/fragmentation cycles. Biochimica Et Biophysica Acta. 1723: 229-39. PMID 15814299 DOI: 10.1016/J.Bbagen.2005.02.013  0.413
2005 Robijn ML, Wuhrer M, Kornelis D, Deelder AM, Geyer R, Hokke CH. Mapping fucosylated epitopes on glycoproteins and glycolipids of Schistosoma mansoni cercariae, adult worms and eggs. Parasitology. 130: 67-77. PMID 15700758 DOI: 10.1017/S0031182004006390  0.531
2005 Wuhrer M, Koeleman CA, Hokke CH, Deelder AM. Protein glycosylation analyzed by normal-phase nano-liquid chromatography--mass spectrometry of glycopeptides. Analytical Chemistry. 77: 886-94. PMID 15679358 DOI: 10.1021/Ac048619X  0.389
2004 Wuhrer M, Hokke CH, Deelder AM. Glycopeptide analysis by matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry reveals novel features of horseradish peroxidase glycosylation. Rapid Communications in Mass Spectrometry : Rcm. 18: 1741-8. PMID 15282773 DOI: 10.1002/Rcm.1546  0.36
2004 Geyer H, Wuhrer M, Kurokawa T, Geyer R. Characterization of keyhole limpet hemocyanin (KLH) glycans sharing a carbohydrate epitope with Schistosoma mansoni glycoconjugates. Micron (Oxford, England : 1993). 35: 105-6. PMID 15036307 DOI: 10.1016/J.Micron.2003.10.033  0.63
2004 Wuhrer M, Koeleman CA, Deelder AM, Hokke CH. Normal-phase nanoscale liquid chromatography-mass spectrometry of underivatized oligosaccharides at low-femtomole sensitivity. Analytical Chemistry. 76: 833-8. PMID 14750882 DOI: 10.1021/Ac034936C  0.368
2004 Wuhrer M, Grimm C, Dennis RD, Idris MA, Geyer R. The parasitic trematode Fasciola hepatica exhibits mammalian-type glycolipids as well as Gal(beta1-6)Gal-terminating glycolipids that account for cestode serological cross-reactivity. Glycobiology. 14: 115-26. PMID 14638629 DOI: 10.1093/Glycob/Cwh021  0.569
2004 Wuhrer M, Robijn ML, Koeleman CA, Balog CI, Geyer R, Deelder AM, Hokke CH. A novel Gal(beta1-4)Gal(beta1-4)Fuc(alpha1-6)-core modification attached to the proximal N-acetylglucosamine of keyhole limpet haemocyanin (KLH) N-glycans. The Biochemical Journal. 378: 625-32. PMID 14613482 DOI: 10.1042/Bj20031380  0.558
2004 Wuhrer M, Koeleman CA, Hokke CH, Deelder AM. Nano-scale liquid chromatography-mass spectrometry of 2-aminobenzamide-labeled oligosaccharides at low femtomole sensitivity International Journal of Mass Spectrometry. 232: 51-57. DOI: 10.1016/J.Ijms.2003.11.009  0.347
2003 Wuhrer M, Geyer H, von der Ohe M, Gerardy-Schahn R, Schachner M, Geyer R. Localization of defined carbohydrate epitopes in bovine polysialylated NCAM. Biochimie. 85: 207-18. PMID 12765790 DOI: 10.1016/S0300-9084(03)00043-9  0.628
2003 Wuhrer M, Grimm C, Zahringer U, Dennis RD, Berkefeld CM, Idris MA, Geyer R. A novel GlcNAcalpha1-HPO3-6Gal(1-1)ceramide antigen and alkylated inositol-phosphoglycerolipids expressed by the liver fluke Fasciola hepatica. Glycobiology. 13: 129-37. PMID 12626405 DOI: 10.1093/Glycob/Cwg005  0.584
2003 Wuhrer M, Grimm C, Zähringer U, Dennis RD, Berkefeld CM, Idris MA, Geyer R. Erratum: "A novel GlcNAα1-HPO3-6Gal(1-1)ceramide antigen and alkylated inositol-phosphoglycerolipids expressed by the liver fluke Fasciola hepatica" (Glycobiology vol. 13(2) (129-137)) Glycobiology. 13. DOI: 10.1093/Glycob/Cwg108  0.529
2002 Stamm I, Wuhrer M, Geyer R, Baljer G, Menge Ch. Bovine lymphocytes express functional receptors for Escherichia coli Shiga toxin 1. Microbial Pathogenesis. 33: 251-64. PMID 12495672 DOI: 10.1006/Mpat.2002.0527  0.577
2002 Kurokawa T, Wuhrer M, Lochnit G, Geyer H, Markl J, Geyer R. Hemocyanin from the keyhole limpet Megathura crenulata (KLH) carries a novel type of N-glycans with Gal(beta1-6)Man-motifs. European Journal of Biochemistry. 269: 5459-73. PMID 12423344 DOI: 10.1046/J.1432-1033.2002.03244.X  0.636
2002 Schmitt J, Wuhrer M, Hamburger J, Jourdane J, Ramzy RM, Geyer R, Ruppel A. Schistosoma mansoni and Schistosoma haematobium: identification and characterization of glycoconjugate antigens in the hemolymph of infected vector snails. The Journal of Parasitology. 88: 505-13. PMID 12099419 DOI: 10.1645/0022-3395(2002)088[0505:Smashi]2.0.Co;2  0.6
2002 Kantelhardt SR, Wuhrer M, Dennis RD, Doenhoff MJ, Bickle Q, Geyer R. Fuc(alpha1-->3)GalNAc-: the major antigenic motif of Schistosoma mansoni glycolipids implicated in infection sera and keyhole-limpet haemocyanin cross-reactivity. The Biochemical Journal. 366: 217-23. PMID 11996672 DOI: 10.1042/Bj20011678  0.587
2002 Wuhrer M, Kantelhardt SR, Dennis RD, Doenhoff MJ, Lochnit G, Geyer R. Characterization of glycosphingolipids from Schistosoma mansoni eggs carrying Fuc(alpha1-3)GalNAc-, GalNAc(beta1-4)[Fuc(alpha1-3)]GlcNAc- and Gal(beta1-4)[Fuc(alpha1-3)]GlcNAc- (Lewis X) terminal structures. European Journal of Biochemistry. 269: 481-93. PMID 11856306 DOI: 10.1046/J.0014-2956.2001.02673.X  0.528
2002 von Der Ohe M, Wheeler SF, Wuhrer M, Harvey DJ, Liedtke S, Mühlenhoff M, Gerardy-Schahn R, Geyer H, Dwek RA, Geyer R, Wing DR, Schachner M. Localization and characterization of polysialic acid-containing N-linked glycans from bovine NCAM. Glycobiology. 12: 47-63. PMID 11825886 DOI: 10.1093/Glycob/12.1.47  0.63
2001 Menge C, Stamm I, Wuhrer M, Geyer R, Wieler LH, Baljer G. Globotriaosylceramide (Gb(3)/CD77) is synthesized and surface expressed by bovine lymphocytes upon activation in vitro. Veterinary Immunology and Immunopathology. 83: 19-36. PMID 11604159 DOI: 10.1016/S0165-2427(01)00365-8  0.546
2001 Liedtke S, Geyer H, Wuhrer M, Geyer R, Frank G, Gerardy-Schahn R, Zähringer U, Schachner M. Characterization of N-glycans from mouse brain neural cell adhesion molecule. Glycobiology. 11: 373-84. PMID 11425798 DOI: 10.1093/Glycob/11.5.373  0.639
2001 Wuhrer M, Berkefeld C, Dennis RD, Idris MA, Geyer R. The liver flukes Fasciola gigantica and Fasciola hepatica express the leucocyte cluster of differentiation marker CD77 (globotriaosylceramide) in their tegument. Biological Chemistry. 382: 195-207. PMID 11308018 DOI: 10.1515/Bc.2001.027  0.565
2001 Wuhrer M, Dennis RD, Doenhoff MJ, Geyer R. Stage-associated expression of ceramide structures in glycosphingolipids from the human trematode parasite Schistosoma mansoni. Biochimica Et Biophysica Acta. 1524: 155-61. PMID 11113562 DOI: 10.1016/S0304-4165(00)00152-5  0.532
2001 Wuhrer M, Dennis RD, Doenhoff MJ, Geyer R. A fucose-containing epitope is shared by keyhole limpet haemocyanin and Schistosoma mansoni glycosphingolipids. Molecular and Biochemical Parasitology. 110: 237-46. PMID 11071279 DOI: 10.1016/S0166-6851(00)00273-5  0.592
2000 Wuhrer M, Dennis RD, Doenhoff MJ, Lochnit G, Geyer R. Schistosoma mansoni cercarial glycolipids are dominated by Lewis X and pseudo-Lewis Y structures. Glycobiology. 10: 89-101. PMID 10570227 DOI: 10.1093/Glycob/10.1.89  0.527
2000 WUHRER M, RICKHOFF S, DENNIS RD, LOCHNIT G, SOBOSLAY PT, BAUMEISTER S, GEYER R. Phosphocholine-containing, zwitterionic glycosphingolipids of adult Onchocerca volvulus as highly conserved antigenic structures of parasitic nematodes Biochemical Journal. 348: 417-423. DOI: 10.1042/Bj3480417  0.57
1999 Wuhrer M, Dennis RD, Doenhoff MJ, Bickle Q, Lochnit G, Geyer R. Immunochemical characterisation of Schistosoma mansoni glycolipid antigens. Molecular and Biochemical Parasitology. 103: 155-69. PMID 10551360 DOI: 10.1016/S0166-6851(99)00123-1  0.616
1999 Geyer H, Schmitt S, Wuhrer M, Geyer R. Structural analysis of glycoconjugates by on-target enzymatic digestion and MALDI-TOF-MS. Analytical Chemistry. 71: 476-82. PMID 9949734 DOI: 10.1021/Ac980712W  0.587
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