Year |
Citation |
Score |
2021 |
Qiao JB, Zhang YQ, Yao QW, Zhao ZZ, Peng X, Shu XZ. Enantioselective Reductive Divinylation of Unactivated Alkenes by Nickel-Catalyzed Cyclization Coupling Reaction. Journal of the American Chemical Society. PMID 34384022 DOI: 10.1021/jacs.1c05670 |
0.478 |
|
2021 |
Pang X, Zhao ZZ, Wei XX, Qi L, Xu GL, Duan J, Liu XY, Shu XZ. Regiocontrolled Reductive Vinylation of Aliphatic 1,3-Dienes with Vinyl Triflates by Nickel Catalysis. Journal of the American Chemical Society. PMID 33724807 DOI: 10.1021/jacs.1c00142 |
0.384 |
|
2020 |
Guo P, Wang K, Jin WJ, Xie H, Qi L, Liu XY, Shu XZ. Dynamic Kinetic Cross-Electrophile Arylation of Benzyl Alcohols by Nickel Catalysis. Journal of the American Chemical Society. PMID 33370103 DOI: 10.1021/jacs.0c12462 |
0.323 |
|
2020 |
Shu XZ, Duan J, Wang K, Xu GL, Kang S, Qi L, Liu XY. Cross-Electrophile Csp2-Si Coupling of Vinyl Chlorosilanes. Angewandte Chemie (International Ed. in English). PMID 32902100 DOI: 10.1002/anie.202010737 |
0.323 |
|
2020 |
Qiao JB, Zhao ZZ, Zhang YQ, Yin K, Tian ZX, Shu XZ. Allylboronates from Vinyl Triflates and α-Chloroboronates by Reductive Nickel Catalysis. Organic Letters. PMID 32558584 DOI: 10.1021/acs.orglett.0c01683 |
0.342 |
|
2020 |
Shu X, Pang X, Peng X. Reductive Cross-Coupling of Vinyl Electrophiles Synthesis. 52: 3751-3763. DOI: 10.1055/s-0040-1707342 |
0.33 |
|
2019 |
Duan J, Du YF, Pang X, Shu XZ. Ni-catalyzed cross-electrophile coupling between vinyl/aryl and alkyl sulfonates: synthesis of cycloalkenes and modification of peptides. Chemical Science. 10: 8706-8712. PMID 31803446 DOI: 10.1039/c9sc03347e |
0.374 |
|
2019 |
Pan FF, Guo P, Li CL, Su P, Shu XZ. Enones from Acid Fluorides and Vinyl Triflates by Reductive Nickel Catalysis. Organic Letters. PMID 31066568 DOI: 10.1021/acs.orglett.9b01164 |
0.338 |
|
2019 |
Tian ZX, Qiao JB, Xu GL, Pang X, Qi L, Ma WY, Zhao ZZ, Duan J, Du YF, Su P, Liu XY, Shu XZ. Highly Enantioselective Cross-Electrophile Aryl-Alkenylation of Unactivated Alkenes. Journal of the American Chemical Society. PMID 31002758 DOI: 10.1021/jacs.9b03863 |
0.405 |
|
2019 |
Pang X, He R, Shu X. Construction of C–C Bond via C–N and C–O Cleavage Synlett. 31: 635-640. DOI: 10.1055/s-0039-1691525 |
0.352 |
|
2018 |
Yan XB, Li CL, Jin WJ, Guo P, Shu XZ. Reductive coupling of benzyl oxalates with highly functionalized alkyl bromides by nickel catalysis. Chemical Science. 9: 4529-4534. PMID 29896396 DOI: 10.1039/c8sc00609a |
0.42 |
|
2016 |
Song W, Lynch JC, Shu X, Tang W. ChemInform Abstract: Rhodium-Catalyzed [5 + 2] Cycloaddition of 3-Acyloxy-1,4-enyne with Alkene or Allene. Cheminform. 47. DOI: 10.1002/CHIN.201643029 |
0.484 |
|
2016 |
Song W, Lynch JC, Shu X, Tang W. Rhodium‐Catalyzed [5+2] Cycloaddition of 3‐Acyloxy‐1,4‐enyne with Alkene or Allene Advanced Synthesis & Catalysis. 358: 2007-2011. DOI: 10.1002/Adsc.201600196 |
0.596 |
|
2015 |
Shu XZ, Schienebeck CM, Li X, Zhou X, Song W, Chen L, Guzei IA, Tang W. Rhodium-Catalyzed Stereoselective Intramolecular [5 + 2] Cycloaddition of 3-Acyloxy 1,4-Enyne and Alkene. Organic Letters. PMID 26440751 DOI: 10.1021/Acs.Orglett.5B02665 |
0.621 |
|
2015 |
Shu X, Nguyen SC, He Y, Oba F, Zhang Q, Canlas C, Somorjai GA, Alivisatos AP, Toste FD. ChemInform Abstract: Silica-Supported Cationic Gold(I) Complexes as Heterogeneous Catalysts for Regio- and Enantioselective Lactonization Reactions. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201546159 |
0.313 |
|
2014 |
Schienebeck CM, Li X, Shu XZ, Tang W. 3-Acyloxy-1,4-enyne: a New Five-carbon Synthon for Rhodium-Catalyzed (5+2) Cycloadditions. Pure and Applied Chemistry. Chimie Pure Et Appliquee. 86: 409-417. PMID 24839310 DOI: 10.1515/Pac-2014-5042 |
0.633 |
|
2014 |
Shu XZ, Zhang M, He Y, Frei H, Toste FD. Dual visible light photoredox and gold-catalyzed arylative ring expansion. Journal of the American Chemical Society. 136: 5844-7. PMID 24730447 DOI: 10.1021/Ja500716J |
0.408 |
|
2014 |
Schienebeck CM, Li X, Shu X, Tang W. ChemInform Abstract: 3-Acyloxy-1,4-enyne: A New Five-Carbon Synthon for Rhodium-Catalyzed [5 + 2] Cycloadditions Cheminform. 45: no-no. DOI: 10.1002/CHIN.201444276 |
0.324 |
|
2014 |
Shu X, Zhang M, He Y, Frei H, Toste FD. ChemInform Abstract: Dual Visible Light Photoredox and Gold-Catalyzed Arylative Ring Expansion. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201441035 |
0.315 |
|
2013 |
Shu XZ, Schienebeck CM, Song W, Guzei IA, Tang W. Transfer of chirality in the rhodium-catalyzed intramolecular [5+2] cycloaddition of 3-acyloxy-1,4-enynes (ACEs) and alkynes: synthesis of enantioenriched bicyclo[5.3.0]decatrienes. Angewandte Chemie (International Ed. in English). 52: 13601-5. PMID 24150975 DOI: 10.1002/Anie.201306919 |
0.567 |
|
2013 |
Xu X, Liu P, Shu XZ, Tang W, Houk KN. Rh-catalyzed (5+2) cycloadditions of 3-acyloxy-1,4-enynes and alkynes: computational study of mechanism, reactivity, and regioselectivity. Journal of the American Chemical Society. 135: 9271-4. PMID 23725341 DOI: 10.1021/Ja4036785 |
0.567 |
|
2013 |
Shu X, Shu D, Schienebeck CM, Tang W. ChemInform Abstract: Rhodium-Catalyzed Acyloxy Migration of Propargylic Esters in Cycloadditions, Inspiration from the Recent “Gold Rush” Cheminform. 44: no-no. DOI: 10.1002/CHIN.201313218 |
0.443 |
|
2012 |
Shu XZ, Shu D, Schienebeck CM, Tang W. Rhodium-catalyzed acyloxy migration of propargylic esters in cycloadditions, inspiration from the recent "gold rush". Chemical Society Reviews. 41: 7698-711. PMID 22895533 DOI: 10.1039/C2Cs35235D |
0.551 |
|
2012 |
Yang YF, Shu XZ, Luo JY, Ali S, Liang YM. Platinum-catalyzed cyclization/[1,2]-alkyl migration/allyl shift/cyclization cascade of epoxy alkynyl allyl ethers: a step-economical route to spirobenzo[h]chromanones. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8600-4. PMID 22678919 DOI: 10.1002/chem.201200126 |
0.401 |
|
2012 |
Shu XZ, Li X, Shu D, Huang S, Schienebeck CM, Zhou X, Robichaux PJ, Tang W. Rhodium-catalyzed intra- and intermolecular [5 + 2] cycloaddition of 3-acyloxy-1,4-enyne and alkyne with concomitant 1,2-acyloxy migration. Journal of the American Chemical Society. 134: 5211-21. PMID 22364320 DOI: 10.1021/Ja2109097 |
0.648 |
|
2012 |
Yang Y, Shu X, Luo J, Ali S, Liang Y. ChemInform Abstract: Platinum-Catalyzed Cyclization/[1,2]-Alkyl Migration/Allyl Shift/Cyclization Cascade of Epoxy Alkynyl Allyl Ethers: A Step-Economical Route to Spirobenzo[h]chromanones. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201246149 |
0.404 |
|
2012 |
Shu X, Li X, Shu D, Huang S, Schienebeck CM, Zhou X, Robichaux PJ, Tang W. ChemInform Abstract: Rhodium-Catalyzed Intra- and Intermolecular [5 + 2] Cycloaddition of 3-Acyloxy-1,4-enyne and Alkyne with Concomitant 1,2-Acyloxy Migration. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201232053 |
0.475 |
|
2011 |
Shu XZ, Huang S, Shu D, Guzei IA, Tang W. Interception of a Rautenstrauch intermediate by alkynes for [5+2] cycloaddition: rhodium-catalyzed cycloisomerization of 3-acyloxy-4-ene-1,9-diynes to bicyclo[5.3.0]decatrienes. Angewandte Chemie (International Ed. in English). 50: 8153-6. PMID 21748834 DOI: 10.1002/Anie.201103136 |
0.586 |
|
2011 |
Yang YF, Shu XZ, Wei HL, Luo JY, Ali S, Liu XY, Liang YM. FeCl3-mediated synthesis of polysubstituted tetrahydroquinolines via domino Mannich/Friedel-Crafts reactions of aldehydes and amines. Organic & Biomolecular Chemistry. 9: 5028-33. PMID 21643590 DOI: 10.1039/c1ob05646h |
0.418 |
|
2011 |
Zhao SC, Shu XZ, Ji KG, Zhou AX, He T, Liu XY, Liang YM. Pd(0)-catalyzed [1,5]-sigmatropic hydrogen shift of propargylic esters toward substituent naphthylamines. The Journal of Organic Chemistry. 76: 1941-4. PMID 21314095 DOI: 10.1021/Jo1024267 |
0.301 |
|
2011 |
Xia XF, Shu XZ, Ji KG, Shaukat A, Liu XY, Liang YM. Platinum/scandium-cocatalyzed cascade cyclization and ring-opening reaction of tertiary amines with substituted salicylaldehydes to synthesize 3-(aminoalkyl)coumarins. The Journal of Organic Chemistry. 76: 342-5. PMID 21141942 DOI: 10.1021/jo102219z |
0.458 |
|
2011 |
Shu X, Huang S, Shu D, Guzei IA, Tang W. ChemInform Abstract: Interception of a Rautenstrauch Intermediate by Alkynes for [5 + 2] Cycloaddition: Rhodium-Catalyzed Cycloisomerization of 3-Acyloxy-4-ene-1,9-diynes to Bicyclo[5.3.0]decatrienes. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201201046 |
0.484 |
|
2011 |
Yang Y, Shu X, Wei H, Luo J, Ali S, Liu X, Liang Y. ChemInform Abstract: FeCl3-Mediated Synthesis of Polysubstituted Tetrahydroquinolines via Domino Mannich/Friedel-Crafts Reactions of Aldehydes and Amines. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201149140 |
0.419 |
|
2011 |
Xia X, Shu X, Ji K, Shaukat A, Liu X, Liang Y. ChemInform Abstract: Platinum/Scandium-Cocatalyzed Cascade Cyclization and Ring-Opening Reaction of Tertiary Amines with Substituted Salicylaldehydes to Synthesize 3-(Aminoalkyl)coumarins. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201116139 |
0.461 |
|
2010 |
Shu XZ, Yang YF, Xia XF, Ji KG, Liu XY, Liang YM. Platinum-catalyzed cross-dehydrogenative coupling reaction in the absence of oxidant. Organic & Biomolecular Chemistry. 8: 4077-9. PMID 20664883 DOI: 10.1039/c0ob00261e |
0.317 |
|
2010 |
Ji KG, Zhu HT, Yang F, Shu XZ, Zhao SC, Liu XY, Shaukat A, Liang YM. A novel iodine-promoted tandem cyclization: an efficient synthesis of substituted 3,4-diiodoheterocyclic compounds. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 6151-4. PMID 20422661 DOI: 10.1002/chem.201000518 |
0.337 |
|
2010 |
Ji K, Zhu H, Yang F, Shu X, Zhao S, Liu X, Shaukat A, Liang Y. ChemInform Abstract: A Novel Iodine-Promoted Tandem Cyclization: An Efficient Synthesis of Substituted 3,4-Diiodoheterocyclic Compounds. Cheminform. 41. DOI: 10.1002/CHIN.201042093 |
0.349 |
|
2010 |
Hu Y, Hu J, Wang X, Guo L, Shu X, Niu Y, Liang Y. ChemInform Abstract: Copper-Catalyzed Tandem Synthesis of [1,2,3]Triazolo[5,1-a]isoquinolines and Their Transformation to 1,3-Disubstituted Isoquinolines. Cheminform. 41. DOI: 10.1002/CHIN.201018130 |
0.31 |
|
2009 |
Zheng ZJ, Shu XZ, Ji KG, Zhao SC, Liang YM. Acid-catalyzed skeletal rearrangement of epoxy alkynes: a fast access to highly functionalized allenes. Organic Letters. 11: 3214-7. PMID 19586032 DOI: 10.1021/ol9014199 |
0.425 |
|
2009 |
Ji KG, Shu XZ, Chen J, Zhao SC, Zheng ZJ, Liu XY, Liang YM. Gold-catalyzed tandem cyclization/Friedel-Crafts type reactions toward furan derivatives. Organic & Biomolecular Chemistry. 7: 2501-5. PMID 19503919 DOI: 10.1039/b905332h |
0.384 |
|
2009 |
Niu Y, Yan Z, Gao G, Wang H, Shu X, Ji K, Liang Y. Synthesis of Isoquinoline Derivatives via Ag- Catalyzed Cyclization of 2-Alkynyl Benzyl Azides Journal of Organic Chemistry. 74: 2893-2896. PMID 19271738 DOI: 10.1021/Jo900010M |
0.429 |
|
2009 |
Lu L, Liu XY, Shu XZ, Yang K, Ji KG, Liang YM. Platinum-catalyzed cycloisomerization reaction of 1,6-enyne coupling with rearrangement of propargylic esters. The Journal of Organic Chemistry. 74: 474-7. PMID 19053589 DOI: 10.1021/jo802043z |
0.466 |
|
2009 |
Bian Y, Liu X, Ji K, Shu X, Guo L, Liang Y. Efficient synthesis of highly substituted pyrroles based on the tandem reactions: intermolecular amination and Pd(II)-catalyzed intramolecular hydroamidation Tetrahedron. 65: 1424-1429. DOI: 10.1016/J.TET.2008.12.018 |
0.343 |
|
2009 |
Ji K, Shu X, Chen J, Zhao S, Zheng Z, Liu X, Liang Y. ChemInform Abstract: Gold-Catalyzed Tandem Cyclization/Friedel-Crafts Type Reactions Toward Furan Derivatives. Cheminform. 40. DOI: 10.1002/CHIN.200946102 |
0.383 |
|
2009 |
Niu Y, Yan Z, Gao G, Wang H, Shu X, Ji K, Liang Y. ChemInform Abstract: Synthesis of Isoquinoline Derivatives via Ag-Catalyzed Cyclization of 2-Alkynyl Benzyl Azides. Cheminform. 40. DOI: 10.1002/CHIN.200933158 |
0.349 |
|
2009 |
Bian Y, Liu X, Ji K, Shu X, Guo L, Liang Y. ChemInform Abstract: Efficient Synthesis of Highly Substituted Pyrroles Based on the Tandem Reactions: Intermolecular Amination and Pd(II)-Catalyzed Intramolecular Hydroamidation. Cheminform. 40. DOI: 10.1002/CHIN.200923110 |
0.352 |
|
2009 |
Shu X, Zhao S, Ji K, Zheng Z, Liu X, Liang Y. ChemInform Abstract: Platinum-Catalyzed Cyclization of o-Alkynyl(oxo)benzenes with Alkenes by 1,2-Migration of Benzene: Synthesis of 8-Oxabicyclo[3.2.1]octane Derivatives. Cheminform. 40. DOI: 10.1002/CHIN.200919092 |
0.368 |
|
2009 |
Lu L, Liu X, Shu X, Yang K, Ji K, Liang Y. ChemInform Abstract: Platinum-Catalyzed Cycloisomerization Reaction of 1,6-Enyne Coupling with Rearrangement of Propargylic Esters. Cheminform. 40. DOI: 10.1002/CHIN.200917035 |
0.396 |
|
2009 |
Shu X, Ji K, Zhao S, Zheng Z, Chen J, Lu L, Liu X, Liang Y. ChemInform Abstract: Synthesis of Naphthalenyl Acetate by Platinum-Catalyzed [1,5]-Sigmatropic Hydrogen Shift of Propargylic Esters. Cheminform. 40. DOI: 10.1002/CHIN.200912109 |
0.366 |
|
2009 |
Ji K, Shu X, Chen J, Zhao S, Zheng Z, Lu L, Liu X, Liang Y. ChemInform Abstract: PtCl2-Catalyzed Tandem Triple Migration Reaction Toward (Z)-1,5-Dien-2-yl Esters. Cheminform. 40. DOI: 10.1002/CHIN.200902035 |
0.413 |
|
2008 |
Shu XZ, Ji KG, Zhao SC, Zheng ZJ, Chen J, Lu L, Liu XY, Liang YM. Synthesis of naphthalenyl acetate by platinum-catalyzed [1,5]-sigmatropic hydrogen shift of propargylic esters. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10556-9. PMID 18932180 DOI: 10.1002/chem.200801591 |
0.364 |
|
2008 |
Ji KG, Shu XZ, Chen J, Zhao SC, Zheng ZJ, Lu L, Liu XY, Liang YM. PtCl2-catalyzed tandem triple migration reaction toward (Z)-1,5-dien-2-yl esters. Organic Letters. 10: 3919-22. PMID 18671405 DOI: 10.1021/ol8015463 |
0.441 |
|
2008 |
Shu XZ, Liu XY, Ji KG, Xiao HQ, Liang YM. Au-catalyzed tandem cyclization/[1,2]-alkyl migration reaction of epoxy alkynes: synthesis of spiropyranones. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 5282-9. PMID 18464241 DOI: 10.1002/chem.200800194 |
0.435 |
|
2008 |
Bi HP, Liu XY, Gou FR, Guo LN, Duan XH, Shu XZ, Liang YM. Highly regioselective synthesis of spirocyclic compounds by a palladium-catalyzed intermolecular tandem reaction. Angewandte Chemie (International Ed. in English). 46: 7068-71. PMID 17683031 DOI: 10.1002/ANIE.200702238 |
0.427 |
|
2008 |
Shu X, Zhao S, Ji K, Zheng Z, Liu X, Liang Y. Platinum-Catalyzed Cyclization of o-Alkynyl(oxo)benzenes with Alkenes by 1,2-Migration of Benzene: Synthesis of 8-Oxabicyclo[3.2.1]octane Derivatives European Journal of Organic Chemistry. 2009: 117-122. DOI: 10.1002/EJOC.200800888 |
0.359 |
|
2008 |
Ji K, Shen Y, Shu X, Xiao H, Bian Y, Liang Y. ChemInform Abstract: Synthesis of Difurylmethane Derivatives via the Gold-Catalyzed Tandem Cycloisomerization/Dimerization of Epoxide Alkynes. Cheminform. 39. DOI: 10.1002/CHIN.200844110 |
0.423 |
|
2008 |
Shu X, Liu X, Ji K, Xiao H, Liang Y. ChemInform Abstract: Au-Catalyzed Tandem Cyclization/[1,2]-Alkyl Migration Reaction of Epoxy Alkynes: Synthesis of Spiropyranones. Cheminform. 39. DOI: 10.1002/CHIN.200842116 |
0.463 |
|
2008 |
Shu X, Liu X, Xiao H, Ji K, Guo L, Liang Y. ChemInform Abstract: Tandem Gold(III)-Catalyzed Amination-Intramolecular Hydroamination Reactions of 1-En-4-yn-3-ols with Sulfonamides: Efficient Approach to Highly Substituted Pyrroles. Cheminform. 39. DOI: 10.1002/CHIN.200822120 |
0.419 |
|
2008 |
Xiao H, Shu X, Ji K, Qi C, Liang Y. ChemInform Abstract: Au(III)-Catalyzed Ring Opening Reaction of 1-Cyclopropyl-2-yn-1-ols with Nucleophiles: Highly Efficient Approach to (Z)-Conjugated Enynes. Cheminform. 39. DOI: 10.1002/CHIN.200821096 |
0.421 |
|
2008 |
Shu X, Liu X, Xiao H, Ji K, Guo L, Qi C, Liang Y. ChemInform Abstract: Gold-Catalyzed Tandem Cycloisomerization of Alkynyloxiranes with Nucleophiles: An Efficient Approach to 2,5-Disubstituted Furans. Cheminform. 39. DOI: 10.1002/CHIN.200814113 |
0.329 |
|
2008 |
Ji KG, Shen YW, Shu XZ, Xiao HQ, Bian YJ, Liang YM. Synthesis of difurylmethane derivatives via the gold-catalyzed tandem cycloisomerization/dimerization of epoxide alkynes Advanced Synthesis and Catalysis. 350: 1275-1280. DOI: 10.1002/adsc.200800130 |
0.419 |
|
2008 |
Shu X, Liu X, Xiao H, Ji K, Guo L, Liang Y. Tandem Gold(III)-Catalyzed Amination-Intramolecular Hydroamination Reactions of 1-En-4-yn-3-ols with Sulfonamides: Efficient Approach to Highly Substituted Pyrroles Advanced Synthesis & Catalysis. 350: 243-248. DOI: 10.1002/ADSC.200700452 |
0.407 |
|
2007 |
Xiao H, Shu X, Ji K, Qi C, Liang Y. Au(iii)-catalyzed ring opening reaction of 1-cyclopropyl-2-yn-1-ols with nucleophiles: highly efficient approach to (Z)-conjugated enynes New Journal of Chemistry. 31: 2041. DOI: 10.1039/B714511J |
0.407 |
|
2007 |
Bi H, Liu X, Gou F, Guo L, Duan X, Shu X, Liang Y. Highly Regioselective Synthesis of Spirocyclic Compounds by a Palladium-Catalyzed Intermolecular Tandem Reaction. Cheminform. 38. DOI: 10.1002/CHIN.200752065 |
0.427 |
|
2007 |
Shu X, Liu X, Xiao H, Ji K, Guo L, Qi C, Liang Y. Gold-Catalyzed Tandem Cycloisomerization of Alkynyloxiranes with Nucleophiles: An Efficient Approach to 2,5-Disubstituted Furans Advanced Synthesis & Catalysis. 349: 2493-2498. DOI: 10.1002/ADSC.200700319 |
0.307 |
|
2006 |
Liang Y, Liu X, Pan Z, Shu X, Duan X. Bu4N[AuCl4]-Catalyzed Synthesis of Highly Substituted Furans from 2-(1-Alkynyl)-2-alken-1-ones in Ionic Liquids: An Air-Stable and Recyclable Catalytic System Synlett. 2006: 1962-1964. DOI: 10.1055/S-2006-947363 |
0.352 |
|
2006 |
Liu X, Pan Z, Shu X, Duan X, Liang Y. Bu4N[AuCl4]-Catalyzed Synthesis of Highly Substituted Furans from 2-(1-Alkynyl)-2-alken-1-ones in Ionic Liquids: An Air-Stable and Recyclable Catalytic System. Cheminform. 37. DOI: 10.1002/CHIN.200649106 |
0.352 |
|
Show low-probability matches. |