Jonathan Z. Long - Publications

Affiliations: 
Stanford University Medical School, Palo Alto, CA, United States 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Potthoff M, Gupta RK, Lee C, Long JZ, Brestoff JR, de Bock K. Cell Metabolism 20th anniversary Voices: Part 3 of 3. Cell Metabolism. 37: 1243-1246. PMID 40466620 DOI: 10.1016/j.cmet.2025.05.006  0.582
2025 Wang Y, Zhang Y, Leung VH, Seradj SH, Sonmez U, Servin-Vences MR, Xiao S, Ren X, Wang L, Mishkanian SA, Kini SA, Long JZ, Lipomi DJ, Ye L, Patapoutian A. A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation. Cell Metabolism. PMID 40054462 DOI: 10.1016/j.cmet.2025.02.004  0.407
2024 Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, ... ... Long JZ, et al. A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites. Cell. PMID 39536746 DOI: 10.1016/j.cell.2024.10.032  0.673
2024 Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, ... ... Long JZ, et al. A secondary β-hydroxybutyrate metabolic pathway linked to energy balance. Biorxiv : the Preprint Server For Biology. PMID 39314488 DOI: 10.1101/2024.09.09.612087  0.675
2024 Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Moya-Garzon MD, Truong SD, Chou JC, Wat LW, ... ... Long JZ, et al. PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity. Nature. PMID 39112712 DOI: 10.1038/s41586-024-07801-6  0.668
2024 Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Dolores Moya-Garzon M, Truong SD, Chou JC, Wat LW, ... ... Long JZ, et al. A PTER-dependent pathway of taurine metabolism linked to energy balance. Biorxiv : the Preprint Server For Biology. PMID 38562797 DOI: 10.1101/2024.03.21.586194  0.671
2023 Lone JB, Long JZ, Svensson KJ. Size matters: the biochemical logic of ligand type in endocrine crosstalk. Life Metabolism. 3. PMID 38425548 DOI: 10.1093/lifemeta/load048  0.622
2023 Wiggenhorn AL, Abuzaid HZ, Coassolo L, Li VL, Tanzo JT, Wei W, Lyu X, Svensson KJ, Long JZ. A class of secreted mammalian peptides with potential to expand cell-cell communication. Nature Communications. 14: 8125. PMID 38065934 DOI: 10.1038/s41467-023-43857-0  0.599
2023 Wiggenhorn AL, Abuzaid HZ, Coassolo L, Li VL, Tanzo JT, Wei W, Lyu X, Svensson KJ, Long JZ. A class of secreted mammalian peptides with potential to expand cell-cell communication. Biorxiv : the Preprint Server For Biology. PMID 37333131 DOI: 10.1101/2023.06.02.543503  0.598
2023 Wei W, Riley NM, Lyu X, Shen X, Guo J, Raun SH, Zhao M, Moya-Garzon MD, Basu H, Sheng-Hwa Tung A, Li VL, Huang W, Wiggenhorn AL, Svensson KJ, Snyder MP, ... ... Long JZ, et al. Organism-wide, cell-type-specific secretome mapping of exercise training in mice. Cell Metabolism. PMID 37141889 DOI: 10.1016/j.cmet.2023.04.011  0.616
2022 Wang Y, Leung VH, Zhang Y, Nudell VS, Loud M, Servin-Vences MR, Yang D, Wang K, Moya-Garzon MD, Li VL, Long JZ, Patapoutian A, Ye L. The role of somatosensory innervation of adipose tissues. Nature. PMID 36045288 DOI: 10.1038/s41586-022-05137-7  0.404
2020 Kim JT, Jedrychowski MP, Wei W, Fernandez D, Fischer CR, Banik SM, Spiegelman BM, Long JZ. A Plasma Protein Network Regulates PM20D1 and N-Acyl Amino Acid Bioactivity. Cell Chemical Biology. PMID 32402239 DOI: 10.1016/J.Chembiol.2020.04.009  0.49
2020 Yoo E, Schulze CJ, Stokes BH, Onguka O, Yeo T, Mok S, Gnädig NF, Zhou Y, Kurita K, Foe IT, Terrell SM, Boucher MJ, Cieplak P, Kumpornsin K, Lee MCS, ... ... Long JZ, et al. The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites. Cell Chemical Biology. PMID 31978322 DOI: 10.1016/J.Chembiol.2020.01.001  0.543
2020 Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace D, Spiegelman BM, Kirichok YV. Molecular Identity and Regulatory Mechanisms of the Mitochondrial Uncoupling Protein of Non-Adipose Tissues Biophysical Journal. 118: 185a. DOI: 10.1016/J.Bpj.2019.11.1127  0.741
2019 Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace DC, Spiegelman BM, Kirichok Y. H transport is an integral function of the mitochondrial ADP/ATP carrier. Nature. 571: 515-520. PMID 31341297 DOI: 10.1038/S41586-019-1400-3  0.734
2018 Long JZ, Roche AM, Berdan CA, Louie SM, Roberts AJ, Svensson KJ, Dou FY, Bateman LA, Mina AI, Deng Z, Jedrychowski MP, Lin H, Kamenecka TM, Asara JM, Griffin PR, et al. Ablation of PM20D1 reveals -acyl amino acid control of metabolism and nociception. Proceedings of the National Academy of Sciences of the United States of America. PMID 29967167 DOI: 10.1073/Pnas.1803389115  0.776
2018 Lin H, Long JZ, Roche AM, Svensson KJ, Dou F, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CM, Louie S, Nomura DK, Spiegelman BM, Griffin PR, et al. Discovery of Hydrolysis-resistant Isoindoline N-Acyl Amino Acid Analogs that Stimulate Mitochondrial Respiration. Journal of Medicinal Chemistry. PMID 29533650 DOI: 10.1021/Acs.Jmedchem.8B00029  0.762
2017 Palmer CJ, Bruckner RJ, Paulo JA, Kazak L, Long JZ, Mina AI, Deng Z, LeClair KB, Hall JA, Hong S, Zushin PH, Smith KL, Gygi SP, Hagen S, Cohen DE, et al. Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue. Molecular Metabolism. 6: 1212-1225. PMID 29031721 DOI: 10.1016/J.Molmet.2017.07.013  0.632
2017 Vishvanath L, Long JZ, Spiegelman BM, Gupta RK. Do Adipocytes Emerge from Mural Progenitors? Cell Stem Cell. 20: 585-586. PMID 28475882 DOI: 10.1016/J.Stem.2017.03.013  0.632
2016 Sylow L, Long J, Lokurkar IA, Zeng X, Richter EA, Spiegelman BM. The cancer drug Dasatinib increases PGC-1α in adipose tissue but has adverse effects on glucose tolerance in obese mice. Endocrinology. en20161398. PMID 27589085 DOI: 10.1210/en.2016-1398  0.479
2016 Long JZ, Svensson KJ, Bateman LA, Lin H, Kamenecka T, Lokurkar IA, Lou J, Rao RR, Chang MR, Jedrychowski MP, Paulo JA, Gygi SP, Griffin PR, Nomura DK, Spiegelman BM. The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria. Cell. PMID 27374330 DOI: 10.1016/J.Cell.2016.05.071  0.773
2016 Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM. A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metabolism. PMID 26876562 DOI: 10.1016/J.Cmet.2016.01.008  0.777
2015 Nass SR, Long JZ, Schlosburg JE, Cravatt BF, Lichtman AH, Kinsey SG. Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 364-70. PMID 25715681 DOI: 10.1007/S11481-015-9593-1  0.459
2015 Zhang Z, Wang W, Zhong P, Liu SJ, Long JZ, Zhao L, Gao HQ, Cravatt BF, Liu QS. Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. Hippocampus. 25: 16-26. PMID 25131612 DOI: 10.1002/Hipo.22344  0.356
2014 Rao RR, Long JZ, White JP, Svensson KJ, Lou J, Lokurkar I, Jedrychowski MP, Ruas JL, Wrann CD, Lo JC, Camera DM, Lachey J, Gygi S, Seehra J, Hawley JA, et al. Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell. 157: 1279-91. PMID 24906147 DOI: 10.1016/J.Cell.2014.03.065  0.762
2014 Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH. Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 350: 196-204. PMID 24849924 DOI: 10.1124/Jpet.114.212753  0.484
2014 Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, Rao RR, Lou J, Lokurkar I, Baur W, Castellot JJ, Rosen ED, Spiegelman BM. A smooth muscle-like origin for beige adipocytes. Cell Metabolism. 19: 810-20. PMID 24709624 DOI: 10.1016/J.Cmet.2014.03.025  0.736
2014 Zhong P, Wang W, Pan B, Liu X, Zhang Z, Long JZ, Zhang HT, Cravatt BF, Liu QS. Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1763-76. PMID 24476943 DOI: 10.1038/Npp.2014.24  0.365
2013 Pryce G, Cabranes A, Fernández-Ruiz J, Bisogno T, Di Marzo V, Long JZ, Cravatt BF, Giovannoni G, Baker D. Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1896-904. PMID 23625705 DOI: 10.1177/1352458513485982  0.448
2013 Blankman JL, Long JZ, Trauger SA, Siuzdak G, Cravatt BF. ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proceedings of the National Academy of Sciences of the United States of America. 110: 1500-5. PMID 23297193 DOI: 10.1073/Pnas.1217121110  0.407
2012 Wise LE, Long KA, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH. Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice. Acs Chemical Neuroscience. 3: 369-78. PMID 22860205 DOI: 10.1021/Cn200130S  0.415
2012 Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 481: 463-8. PMID 22237023 DOI: 10.1038/Nature10777  0.707
2012 Booker L, Kinsey SG, Abdullah RA, Blankman JL, Long JZ, Ezzili C, Boger DL, Cravatt BF, Lichtman AH. The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. British Journal of Pharmacology. 165: 2485-96. PMID 21506952 DOI: 10.1111/J.1476-5381.2011.01445.X  0.569
2012 Sticht MA, Long JZ, Rock EM, Limebeer CL, Mechoulam R, Cravatt BF, Parker LA. Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats. British Journal of Pharmacology. 165: 2425-35. PMID 21470205 DOI: 10.1111/J.1476-5381.2011.01407.X  0.402
2012 Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, et al. Boström et al. reply Nature. 488: E10-E11. DOI: 10.1038/Nature11365  0.631
2011 Nomura DK, Morrison BE, Blankman JL, Long JZ, Kinsey SG, Marcondes MC, Ward AM, Hahn YK, Lichtman AH, Conti B, Cravatt BF. Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. Science (New York, N.Y.). 334: 809-13. PMID 22021672 DOI: 10.1126/Science.1209200  0.634
2011 Long JZ, Cisar JS, Milliken D, Niessen S, Wang C, Trauger SA, Siuzdak G, Cravatt BF. Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids. Nature Chemical Biology. 7: 763-5. PMID 21926997 DOI: 10.1038/Nchembio.659  0.529
2011 Nomura DK, Lombardi DP, Chang JW, Niessen S, Ward AM, Long JZ, Hoover HH, Cravatt BF. Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer. Chemistry & Biology. 18: 846-56. PMID 21802006 DOI: 10.1016/J.Chembiol.2011.05.009  0.68
2011 Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH. Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. The Journal of Pharmacology and Experimental Therapeutics. 339: 173-85. PMID 21719468 DOI: 10.1124/Jpet.111.181370  0.608
2011 Long JZ, Cravatt BF. The metabolic serine hydrolases and their functions in mammalian physiology and disease. Chemical Reviews. 111: 6022-63. PMID 21696217 DOI: 10.1021/Cr200075Y  0.446
2011 Kinsey SG, Nomura DK, O'Neal ST, Long JZ, Mahadevan A, Cravatt BF, Grider JR, Lichtman AH. Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice. The Journal of Pharmacology and Experimental Therapeutics. 338: 795-802. PMID 21659471 DOI: 10.1124/Jpet.110.175778  0.598
2011 Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics. Journal of Medicinal Chemistry. 54: 2805-22. PMID 21428410 DOI: 10.1021/Jm101597X  0.543
2011 Kinsey SG, O'Neal ST, Long JZ, Cravatt BF, Lichtman AH. Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay. Pharmacology, Biochemistry, and Behavior. 98: 21-7. PMID 21145341 DOI: 10.1016/J.Pbb.2010.12.002  0.443
2011 Long JZ, LaCava M, Jin X, Cravatt BF. An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. Journal of Lipid Research. 52: 337-44. PMID 21097653 DOI: 10.1194/Jlr.M012153  0.502
2011 Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain Journal of Medicinal Chemistry. 54: 2805-2822. DOI: 10.2210/Pdb3Oj8/Pdb  0.511
2010 Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, et al. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nature Neuroscience. 13: 1113-9. PMID 20729846 DOI: 10.1038/Nn.2616  0.619
2010 Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nature Neuroscience. 13: 951-7. PMID 20657592 DOI: 10.1038/Nn.2601  0.402
2010 Kinsey SG, Long JZ, Cravatt BF, Lichtman AH. Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms. The Journal of Pain : Official Journal of the American Pain Society. 11: 1420-8. PMID 20554481 DOI: 10.1016/J.Jpain.2010.04.001  0.467
2010 Long JZ, Jin X, Adibekian A, Li W, Cravatt BF. Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. Journal of Medicinal Chemistry. 53: 1830-42. PMID 20099888 DOI: 10.1021/Jm9016976  0.448
2010 Nomura DK, Long JZ, Niessen S, Hoover HS, Ng SW, Cravatt BF. Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell. 140: 49-61. PMID 20079333 DOI: 10.1016/J.Cell.2009.11.027  0.619
2010 Kinsey S, Long J, Cravatt B, Lichtman A. Inhibiting endocannabinoid catabolic enzymes attenuates neuropathic pain via distinct cannabinoid receptor mediated mechanisms of action Brain, Behavior, and Immunity. 24: S6. DOI: 10.1016/J.Bbi.2010.07.019  0.403
2009 Long JZ, Nomura DK, Vann RE, Walentiny DM, Booker L, Jin X, Burston JJ, Sim-Selley LJ, Lichtman AH, Wiley JL, Cravatt BF. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 20270-5. PMID 19918051 DOI: 10.1073/Pnas.0909411106  0.633
2009 Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, Mackie K. Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Molecular Pharmacology. 76: 1220-7. PMID 19767452 DOI: 10.1124/Mol.109.059030  0.422
2009 Pan B, Wang W, Long JZ, Sun D, Hillard CJ, Cravatt BF, Liu QS. Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. The Journal of Pharmacology and Experimental Therapeutics. 331: 591-7. PMID 19666749 DOI: 10.1124/Jpet.109.158162  0.42
2009 Long JZ, Nomura DK, Cravatt BF. Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism. Chemistry & Biology. 16: 744-53. PMID 19635411 DOI: 10.1016/J.Chembiol.2009.05.009  0.646
2009 Kinsey SG, Long JZ, O'Neal ST, Abdullah RA, Poklis JL, Boger DL, Cravatt BF, Lichtman AH. Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 330: 902-10. PMID 19502530 DOI: 10.1124/Jpet.109.155465  0.561
2009 Schlosburg JE, Carlson BL, Ramesh D, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH. Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice. The Aaps Journal. 11: 342-52. PMID 19430909 DOI: 10.1208/S12248-009-9110-7  0.473
2009 Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, Weerapana E, Sadagopan N, Liimatta M, Smith SE, Lazerwith S, Stiff C, Kamtekar S, Bhattacharya K, Zhang Y, et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chemistry & Biology. 16: 411-20. PMID 19389627 DOI: 10.1016/J.Chembiol.2009.02.013  0.76
2009 Long JZ, Li W, Booker L, Burston JJ, Kinsey SG, Schlosburg JE, Pavón FJ, Serrano AM, Selley DE, Parsons LH, Lichtman AH, Cravatt BF. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nature Chemical Biology. 5: 37-44. PMID 19029917 DOI: 10.1038/Nchembio.129  0.458
Show low-probability matches.