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Christian Ducho - Publications

Affiliations: 
Saarland University, Saarbrücken, Saarland, Germany 
Area:
Medicinal chemistry, bioorganic chemistry, chemical biology
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cui Z, Nguyen H, Bhardwaj M, Wang X, Büschleb M, Lemke A, Schütz C, Rohrbacher C, Junghanns P, Koppermann S, Ducho C, Thorson JS, Van Lanen SG. Enzymatic C-H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases. Journal of the American Chemical Society. 143: 19425-19437. PMID 34767710 DOI: 10.1021/jacs.1c08177  0.37
2020 Cui Z, Overbay J, Wang X, Liu X, Zhang Y, Bhardwaj M, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis. Nature Chemical Biology. PMID 32483377 DOI: 10.1038/S41589-020-0548-3  0.356
2019 Heib A, Niro G, Weck SC, Koppermann S, Ducho C. Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit. Molecules (Basel, Switzerland). 25. PMID 31861655 DOI: 10.3390/molecules25010022  0.359
2018 Cui Z, Liu X, Overbay J, Cai W, Wang X, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics. The Journal of Organic Chemistry. PMID 29768920 DOI: 10.1021/Acs.Joc.8B00855  0.335
2015 Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, et al. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24. PMID 25855790 DOI: 10.1074/Jbc.M115.646414  0.325
2013 Hamed RB, Gomez-Castellanos JR, Henry L, Ducho C, McDonough MA, Schofield CJ. The enzymes of β-lactam biosynthesis. Natural Product Reports. 30: 21-107. PMID 23135477 DOI: 10.1039/C2Np20065A  0.61
2012 Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG. Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase. Journal of the American Chemical Society. 134: 18514-7. PMID 23110675 DOI: 10.1021/Ja308185Q  0.416
2012 Hamed RB, Henry L, Gomez-Castellanos JR, Mecinović J, Ducho C, Sorensen JL, Claridge TD, Schofield CJ. Crotonase catalysis enables flexible production of functionalized prolines and carbapenams. Journal of the American Chemical Society. 134: 471-9. PMID 22091817 DOI: 10.1021/Ja208318D  0.648
2011 Spork AP, Wiegmann D, Granitzka M, Stalke D, Ducho C. Stereoselective synthesis of uridine-derived nucleosyl amino acids. The Journal of Organic Chemistry. 76: 10083-98. PMID 22059552 DOI: 10.1021/Jo201935W  0.307
2011 Hamed RB, Gomez-Castellanos JR, Thalhammer A, Harding D, Ducho C, Claridge TD, Schofield CJ. Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases. Nature Chemistry. 3: 365-71. PMID 21505494 DOI: 10.1038/Nchem.1011  0.626
2010 Hamed RB, Mecinović J, Ducho C, Claridge TD, Schofield CJ. Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles. Chemical Communications (Cambridge, England). 46: 1413-5. PMID 20162132 DOI: 10.1039/B924519G  0.576
2009 Ducho C, Hamed RB, Batchelar ET, Sorensen JL, Odell B, Schofield CJ. Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis. Organic & Biomolecular Chemistry. 7: 2770-9. PMID 19532994 DOI: 10.1039/B903312B  0.621
2008 Batchelar ET, Hamed RB, Ducho C, Claridge TD, Edelmann MJ, Kessler B, Schofield CJ. Thioester hydrolysis and C-C bond formation by carboxymethylproline synthase from the crotonase superfamily. Angewandte Chemie (International Ed. in English). 47: 9322-5. PMID 18972478 DOI: 10.1002/Anie.200803906  0.604
2007 Ducho C, Görbig U, Jessel S, Gisch N, Balzarini J, Meier C. Bis-cycloSal-d4T-monophosphates: Drugs That Deliver Two Molecules of Bioactive Nucleotides Journal of Medicinal Chemistry. 50: 1335-1346. PMID 17328534 DOI: 10.1021/Jm0611713  0.445
2004 Meier C, Ducho C, Görbig U, Esnouf R, Balzarini J. Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship. Journal of Medicinal Chemistry. 47: 2839-2852. PMID 15139762 DOI: 10.1021/Jm031032A  0.434
2002 Ducho C, Balzarini J, Naesens L, Clercq ED, Meier C. Aryl-Substituted and Benzo-Annulated CycloSal-Derivatives of 2′,3′-Dideoxy-2′,3′-Didehydrothymidine Monophosphate — Correlation of Structure, Hydrolysis Properties and Anti-HIV Activity Antiviral Chemistry & Chemotherapy. 13: 129-141. PMID 12238530 DOI: 10.1177/095632020201300206  0.491
2002 Meier C, Renze J, Ducho C, Balzarini J. cycloSal-d4TMP Pronucleotides-Structural Variations, Mechanistic Insights and Antiviral Activity Current Topics in Medicinal Chemistry. 2: 1111-1121. PMID 12173970 DOI: 10.2174/1568026023393183  0.453
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