| Year |
Citation |
Score |
| 2025 |
Ren J, Mathew A, Rodríguez-García M, Regli CC, Blacque O, Spingler B, Sieber S, Eberl L, Gademann K. Valdiazen Derivatives for Chemoproteomic Studies in Burkholderia cenocepacia H111. Chembiochem : a European Journal of Chemical Biology. e202400945. PMID 40084497 DOI: 10.1002/cbic.202400945 |
0.681 |
|
| 2024 |
Ren J, Mathew A, Rodríguez-García M, Kohler T, Blacque O, Linden A, Eberl L, Sieber S, Gademann K. Functional biosynthetic stereodivergence in a gene cluster via a dihydrosydnone N-oxide. Communications Chemistry. 7: 301. PMID 39702669 DOI: 10.1038/s42004-024-01372-3 |
0.685 |
|
| 2024 |
Mas-Roselló J, Tenor H, Szabo T, Naef R, Sieber S, Gademann K. Bifunctional Sildenafil Diazeniumdiolates Acting as Phosphodiesterase 5 Inhibitors and Nitric Oxide Donors ̶ Towards Wound Healing. Chembiochem : a European Journal of Chemical Biology. e202300801. PMID 38430555 DOI: 10.1002/cbic.202300801 |
0.667 |
|
| 2023 |
Grayfer TD, Yamani K, Jung E, Chesnokov GA, Ferrara I, Hsiao CC, Georgiou A, Michel J, Bailly A, Sieber S, Eberl L, Gademann K. Allylic Carbocyclic Inhibitors Covalently Bind Glycoside Hydrolases. Jacs Au. 3: 1151-1161. PMID 37124289 DOI: 10.1021/jacsau.3c00037 |
0.693 |
|
| 2021 |
Georgiou A, Sieber S, Hsiao CC, Grayfer T, Gorenflos López JL, Gademann K, Eberl L, Bailly A. Leaf nodule endosymbiotic Burkholderia confer targeted allelopathy to their Psychotria hosts. Scientific Reports. 11: 22465. PMID 34789815 DOI: 10.1038/s41598-021-01867-2 |
0.679 |
|
| 2021 |
Sieber S, Mathew A, Jenul C, Kohler T, Bär M, Carrión VJ, Cazorla FM, Stalder U, Hsieh YC, Bigler L, Eberl L, Gademann K. Mitigation of virulence by signal inactivation. Science Advances. 7: eabg2293. PMID 34516871 DOI: 10.1126/sciadv.abg2293 |
0.648 |
|
| 2020 |
Schnell SD, Hoff LV, Panchagnula A, Wurzenberger MHH, Klapötke TM, Sieber S, Linden A, Gademann K. 3-Bromotetrazine: labelling of macromolecules monosubstituted bifunctional -tetrazines. Chemical Science. 11: 3042-3047. PMID 34122808 DOI: 10.1039/c9sc06169j |
0.73 |
|
| 2020 |
Shchelik I, Sieber S, Gademann K. Green Algae as a Drug Delivery System for the Controlled Release of Antibiotics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32910832 DOI: 10.1002/Chem.202003821 |
0.683 |
|
| 2020 |
Ilazi A, Huang B, de Almeida Campos V, Gademann K. Synthesis of Colibactin Pyrrolidono[3,4-]pyridones via Regioselective C(sp)-H Activation. Organic Letters. 22: 6858-6862. PMID 32815372 DOI: 10.1021/Acs.Orglett.0C02385 |
0.347 |
|
| 2020 |
Stücheli P, Sieber S, Fuchs DW, Scheller L, Strittmatter T, Saxena P, Gademann K, Fussenegger M. Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells. Nucleic Acids Research. PMID 32421771 DOI: 10.1093/Nar/Gkaa342 |
0.691 |
|
| 2020 |
Sieber S, Grendelmeier SM, Harris LA, Mitchell DA, Gademann K. Microviridin 1777: A Toxic Chymotrypsin Inhibitor Discovered by a Metabologenomic Approach. Journal of Natural Products. PMID 31989826 DOI: 10.1021/Acs.Jnatprod.9B00986 |
0.725 |
|
| 2020 |
Sieber S, Daeppen C, Jenul C, Mannancherril V, Eberl L, Gademann K. Biosynthesis and Structure Activity Relationship Investigations of the Diazeniumdiolate Antifungal Agent Fragin. Chembiochem : a European Journal of Chemical Biology. PMID 31945256 DOI: 10.1002/Cbic.201900755 |
0.735 |
|
| 2020 |
Sieber S, Hsiao CC, Emmanouilidou D, Debowski AW, Stubbs KA, Gademann K. Syntheses and biological investigations of kirkamide and oseltamivir hybrid derivatives Tetrahedron. 131386. DOI: 10.1016/J.Tet.2020.131386 |
0.717 |
|
| 2020 |
Dorst A, Shchelik IS, Schäfle D, Sander P, Gademann K. Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics Helvetica Chimica Acta. DOI: 10.1002/Hlca.202000130 |
0.319 |
|
| 2019 |
Hattori H, Hoff LV, Gademann K. Total Synthesis and Structural Revision of Mangrolide D. Organic Letters. 21: 3456-3459. PMID 31012591 DOI: 10.1021/Acs.Orglett.9B01256 |
0.342 |
|
| 2019 |
Huber F, Roesslein J, Gademann K. Preparation of Indolenines via Nucleophilic Aromatic Substitution. Organic Letters. PMID 30835126 DOI: 10.1021/Acs.Orglett.9B00489 |
0.37 |
|
| 2019 |
Schnell SD, Linden A, Gademann K. Synthesis of Two Key Fragments of the Complex Polyhalogenated Marine Meroterpenoid Azamerone. Organic Letters. 21: 1144-1147. PMID 30681874 DOI: 10.1021/Acs.Orglett.9B00090 |
0.378 |
|
| 2019 |
Jenul C, Sieber S, Gademann K, Eberl L. Ein neues Signalmolekül in Burkholderia cenocepacia Biospektrum. 25: 368-371. DOI: 10.1007/S12268-019-1062-6 |
0.703 |
|
| 2018 |
Hsiao CC, Sieber S, Georgiou A, Bailly A, Emmanouilidou D, Carlier A, Eberl L, Gademann K. Synthesis and Biological Evaluation of the Novel Growth Inhibitor Streptol Glucoside, Isolated from an Obligate Plant Symbiont. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30508325 DOI: 10.1002/Chem.201805693 |
0.711 |
|
| 2018 |
Hattori H, Roesslein J, Caspers P, Zerbe K, Miyatake-Ondozabal H, Ritz D, Rueedi G, Gademann K. Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A. Angewandte Chemie (International Ed. in English). PMID 29943519 DOI: 10.1002/Anie.201805770 |
0.379 |
|
| 2018 |
Jenul C, Sieber S, Daeppen C, Mathew A, Lardi M, Pessi G, Hoepfner D, Neuburger M, Linden A, Gademann K, Eberl L. Biosynthesis of fragin is controlled by a novel quorum sensing signal. Nature Communications. 9: 1297. PMID 29602945 DOI: 10.1038/S41467-018-03690-2 |
0.719 |
|
| 2018 |
Hattori H, Kaufmann E, Miyatake-Ondozabal H, Berg R, Gademann K. Total Synthesis of Tiacumicin A. Total Synthesis, Relay Synthesis, and Degradation Studies of Fidaxomicin (Tiacumicin B, Lipiarmycin A3). The Journal of Organic Chemistry. PMID 29590752 DOI: 10.1021/Acs.Joc.8B00101 |
0.368 |
|
| 2018 |
Ilazi A, Liffert R, Gademann K. Total Synthesis of the Polyoxygenated Sesquiterpenes Guignarderemophilanes C and D Helvetica Chimica Acta. 101: e1800011. DOI: 10.1002/Hlca.201800011 |
0.389 |
|
| 2017 |
Liffert R, Gademann K. Mapping Out Biogenetic Hypotheses by Chemical Synthesis. Chimia. 71: 841-844. PMID 29289245 DOI: 10.2533/Chimia.2017.841 |
0.373 |
|
| 2017 |
Liffert R, Linden A, Gademann K. Total Synthesis of the Sesquiterpenoid Periconianone A Based on a Postulated Biogenesis. Journal of the American Chemical Society. PMID 29076340 DOI: 10.1021/Jacs.7B10053 |
0.338 |
|
| 2017 |
Scherer M, Gademann K. Total Synthesis and Structural Revision of Aeruginosin KT608A. Organic Letters. PMID 28696116 DOI: 10.1021/Acs.Orglett.7B01822 |
0.331 |
|
| 2017 |
Chicca A, Berg R, Jessen HJ, Marck N, Schmid F, Burch P, Gertsch J, Gademann K. Biological evaluation of pyridone alkaloids on the endocannabinoid system. Bioorganic & Medicinal Chemistry. PMID 28284861 DOI: 10.1016/J.Bmc.2017.02.031 |
0.584 |
|
| 2017 |
Wehlauch R, Grendelmeier SM, Miyatake-Ondozabal H, Sandtorv AH, Scherer M, Gademann K. Investigating Biogenetic Hypotheses of the Securinega Alkaloids: Enantioselective Total Syntheses of Secu'amamine E/ent-Virosine A and Bubbialine. Organic Letters. PMID 28094969 DOI: 10.1021/Acs.Orglett.6B03716 |
0.348 |
|
| 2017 |
Wehlauch R, Gademann K. Securinega
Alkaloids: Complex Structures, Potent Bioactivities, and Efficient Total Syntheses Asian Journal of Organic Chemistry. 6: 1146-1159. DOI: 10.1002/Ajoc.201700142 |
0.381 |
|
| 2016 |
Thommen C, Neuburger M, Gademann K. Collective Syntheses of Icetexane Natural Products Based on Biogenetic Hypotheses. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27896867 DOI: 10.1002/Chem.201603932 |
0.346 |
|
| 2016 |
Gomes J, Daeppen C, Liffert R, Roesslein J, Kaufmann E, Heikinheimo A, Neuburger M, Gademann K. Formal Total Synthesis of (-)-Jiadifenolide and Synthetic Studies Towards seco-Prezizaane-Type Sesquiterpenes. The Journal of Organic Chemistry. PMID 27740748 DOI: 10.1021/Acs.Joc.6B02039 |
0.378 |
|
| 2016 |
Scherer M, Bezold D, Gademann K. Investigating the Toxicity of the Aeruginosin Chlorosulfopeptides by Chemical Synthesis. Angewandte Chemie (International Ed. in English). PMID 27332048 DOI: 10.1002/Anie.201602755 |
0.32 |
|
| 2016 |
Pinto-Carbó M, Sieber S, Dessein S, Wicker T, Verstraete B, Gademann K, Eberl L, Carlier A. Evidence of horizontal gene transfer between obligate leaf nodule symbionts. The Isme Journal. PMID 26978165 DOI: 10.1038/Ismej.2016.27 |
0.689 |
|
| 2016 |
Crane EA, Gademann K. Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis. Angewandte Chemie (International Ed. in English). PMID 26833854 DOI: 10.1002/Anie.201505863 |
0.334 |
|
| 2015 |
Daeppen C, Kaiser M, Neuburger M, Gademann K. Preparation of Antimalarial Endoperoxides by a Formal [2 + 2 + 2] Cycloaddition. Organic Letters. 17: 5420-3. PMID 26491785 DOI: 10.1021/Acs.Orglett.5B02773 |
0.323 |
|
| 2015 |
Kaufmann E, Hattori H, Miyatake-Ondozabal H, Gademann K. Total Synthesis of the Glycosylated Macrolide Antibiotic Fidaxomicin. Organic Letters. PMID 26125969 DOI: 10.1021/Acs.Orglett.5B01602 |
0.363 |
|
| 2015 |
Sieber S, Carlier A, Neuburger M, Grabenweger G, Eberl L, Gademann K. Isolation and Total Synthesis of Kirkamide, an Aminocyclitol from an Obligate Leaf Nodule Symbiont. Angewandte Chemie (International Ed. in English). 54: 7968-70. PMID 26033226 DOI: 10.1002/Anie.201502696 |
0.715 |
|
| 2015 |
Grundler V, Faltermann S, Fent K, Gademann K. Preparation of Fluorescent Microcystin Derivatives by Direct Arginine Labelling and Their Biological Evaluation. Chembiochem : a European Journal of Chemical Biology. PMID 26010357 DOI: 10.1002/Cbic.201500181 |
0.327 |
|
| 2015 |
Gademann K. Copy, edit, and paste: natural product approaches to biomaterials and neuroengineering. Accounts of Chemical Research. 48: 731-9. PMID 25719515 DOI: 10.1021/Ar500435B |
0.354 |
|
| 2015 |
Miyatake-Ondozabal H, Kaufmann E, Gademann K. Total synthesis of the protected aglycon of fidaxomicin (tiacumicin B, lipiarmycin A3). Angewandte Chemie (International Ed. in English). 54: 1933-6. PMID 25431322 DOI: 10.1002/Anie.201409464 |
0.354 |
|
| 2015 |
Bader SL, Luescher MU, Gademann K. Synthesis of maculalactone A and derivatives for environmental fate tracking studies. Organic & Biomolecular Chemistry. 13: 199-206. PMID 25360848 DOI: 10.1039/C4Ob02042A |
0.374 |
|
| 2015 |
Kerschgens IP, Gademann K. Direct Preparation of Pyrrolizidines Using Imines and Isonitriles Synthesis (Germany). DOI: 10.1055/S-0034-1380433 |
0.33 |
|
| 2014 |
Grundler V, Gademann K. Direct arginine modification in native peptides and application to chemical probe development. Acs Medicinal Chemistry Letters. 5: 1290-5. PMID 25516786 DOI: 10.1021/Ml5003508 |
0.307 |
|
| 2014 |
Burch P, Chicca A, Gertsch J, Gademann K. Functionally Optimized Neuritogenic Farinosone C Analogs: SAR-Study and Investigations on Their Mode of Action. Acs Medicinal Chemistry Letters. 5: 172-7. PMID 24900793 DOI: 10.1021/Ml400435H |
0.345 |
|
| 2014 |
Portmann C, Sieber S, Wirthensohn S, Blom JF, Da Silva L, Baudat E, Kaiser M, Brun R, Gademann K. Balgacyclamides, antiplasmodial heterocyclic peptides from Microcystis aeruguinosa EAWAG 251. Journal of Natural Products. 77: 557-62. PMID 24392715 DOI: 10.1021/Np400814W |
0.69 |
|
| 2014 |
Schmid F, Bernasconi M, Jessen HJ, Pfaltz A, Gademann K. Catalytic enantioselective total synthesis of (-)-pyridovericin Synthesis (Germany). 46: 864-870. DOI: 10.1055/S-0033-1340868 |
0.599 |
|
| 2013 |
Hoecker J, Liffert R, Burch P, Wehlauch R, Gademann K. Caged retinoids as photoinducible activators: implications for cell differentiation and neurite outgrowth. Organic & Biomolecular Chemistry. 11: 3314-21. PMID 23538708 DOI: 10.1039/C3Ob40106E |
0.301 |
|
| 2013 |
Makhlouf Brahmi M, Portmann C, D'Ambrosio D, Woods TM, Banfi D, Reichenbach P, Da Silva L, Baudat E, Turcatti G, Lingner J, Gademann K. Telomerase inhibitors from cyanobacteria: isolation and synthesis of sulfoquinovosyl diacylglycerols from Microcystis aeruguinosa PCC 7806. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 4596-601. PMID 23364876 DOI: 10.1002/Chem.201203296 |
0.333 |
|
| 2013 |
Miyatake-Ondozabal H, Bannwart LM, Gademann K. Enantioselective total synthesis of virosaine A and bubbialidine. Chemical Communications (Cambridge, England). 49: 1921-3. PMID 23364254 DOI: 10.1039/C3Cc38783F |
0.331 |
|
| 2013 |
Hoecker J, Gademann K. Enantioselective total syntheses and absolute configuration of JBIR-02 and Mer-A2026B. Organic Letters. 15: 670-3. PMID 23330661 DOI: 10.1021/Ol303502A |
0.312 |
|
| 2013 |
Burch P, Binaghi M, Scherer M, Wentzel C, Bossert D, Eberhardt L, Neuburger M, Scheiffele P, Gademann K. Total synthesis of gelsemiol. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 2589-91. PMID 23307641 DOI: 10.1002/Chem.201203746 |
0.307 |
|
| 2013 |
Liffert R, Hoecker J, Jana CK, Woods TM, Burch P, Jessen HJ, Neuburger M, Gademann K. Withanolide A: Synthesis and structural requirements for neurite outgrowth Chemical Science. 4: 2851-2857. DOI: 10.1039/C3Sc50653C |
0.602 |
|
| 2013 |
Schmid F, Jessen HJ, Burch P, Gademann K. Truncated militarinone fragments identified by total chemical synthesis induce neurite outgrowth Medchemcomm. 4: 135-139. DOI: 10.1039/C2Md20181J |
0.584 |
|
| 2012 |
Elamparuthi E, Fellay C, Neuburger M, Gademann K. Total synthesis of cyrneine A. Angewandte Chemie (International Ed. in English). 51: 4071-3. PMID 22431475 DOI: 10.1002/Anie.201200515 |
0.342 |
|
| 2012 |
Wach JY, Gademann K. Reduce to the maximum: Truncated natural products as powerful modulators of biological processes Synlett. 163-170. DOI: 10.1055/S-0031-1290125 |
0.364 |
|
| 2011 |
Gademann K, Sieber S. Chemical interference of biological systems with natural products. Chimia. 65: 835-8. PMID 22289366 DOI: 10.2533/Chimia.2011.835 |
0.727 |
|
| 2011 |
Jessen HJ, Schumacher A, Schmid F, Pfaltz A, Gademann K. Catalytic enantioselective total synthesis of (+)-torrubiellone C. Organic Letters. 13: 4368-70. PMID 21797235 DOI: 10.1021/Ol201692H |
0.588 |
|
| 2011 |
Gademann K. Out in the green: biologically active metabolites produced by cyanobacteria. Chimia. 65: 416-9. PMID 21797171 DOI: 10.2533/Chimia.2011.416 |
0.325 |
|
| 2011 |
Jana CK, Hoecker J, Woods TM, Jessen HJ, Neuburger M, Gademann K. Synthesis of withanolide A, biological evaluation of its neuritogenic properties, and studies on secretase inhibition. Angewandte Chemie (International Ed. in English). 50: 8407-11. PMID 21766402 DOI: 10.1002/Anie.201101869 |
0.572 |
|
| 2011 |
Gademann K. Controlling protein transport by small molecules. Current Drug Targets. 12: 1574-80. PMID 21561424 DOI: 10.2174/138945011798109446 |
0.311 |
|
| 2011 |
Jessen HJ, Schumacher A, Shaw T, Pfaltz A, Gademann K. A unified approach for the stereoselective total synthesis of pyridone alkaloids and their neuritogenic activity. Angewandte Chemie (International Ed. in English). 50: 4222-6. PMID 21448865 DOI: 10.1002/Anie.201007671 |
0.591 |
|
| 2011 |
Jana CK, Hoecker J, Woods TM, Jessen HJ, Neuburger M, Gademann K. Synthese von Withanolid A, Untersuchung der neuritogenen Eigenschaften und Studien zur Sekretase-Inhibierung Angewandte Chemie. 123: 8557-8561. DOI: 10.1002/Ange.201101869 |
0.562 |
|
| 2011 |
Jessen HJ, Schumacher A, Shaw T, Pfaltz A, Gademann K. Ein einheitlicher Ansatz zur stereoselektiven Totalsynthese von Pyridonalkaloiden und deren neuritogene Aktivität Angewandte Chemie. 123: 4308-4312. DOI: 10.1002/Ange.201007671 |
0.501 |
|
| 2010 |
Constable EC, Housecroft CE, Creus M, Gademann K, Giese B, Ward TR, Woggon WD, Chougnet A. Bioorganic and bioinorganic chemistry. Chimia. 64: 846-54. PMID 21268991 DOI: 10.2533/Chimia.2010.846 |
0.301 |
|
| 2010 |
Locher HH, Ritz D, Pfaff P, Gaertner M, Knezevic A, Sabato D, Schroeder S, Barbaras D, Gademann K. Dimers of nostocarboline with potent antibacterial activity. Chemotherapy. 56: 318-24. PMID 20714150 DOI: 10.1159/000320033 |
0.33 |
|
| 2010 |
Jana CK, Scopelliti R, Gademann K. A synthetic entry into the taiwaniaquinoids based on a biogenetic hypothesis: total synthesis of (-)-taiwaniaquinone H. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 7692-5. PMID 20533471 DOI: 10.1002/Chem.201001085 |
0.301 |
|
| 2010 |
Jessen HJ, Gademann K. 4-Hydroxy-2-pyridone alkaloids: structures and synthetic approaches. Natural Product Reports. 27: 1168-85. PMID 20532354 DOI: 10.1039/B911516C |
0.612 |
|
| 2010 |
Wach JY, Güttinger S, Kutay U, Gademann K. The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transport. Bioorganic & Medicinal Chemistry Letters. 20: 2843-6. PMID 20381347 DOI: 10.1016/J.Bmcl.2010.03.049 |
0.34 |
|
| 2010 |
Jessen HJ, Gademann K. Total synthesis of the marine alkaloid palau'amine. Angewandte Chemie (International Ed. in English). 49: 2972-4. PMID 20232437 DOI: 10.1002/Anie.201000479 |
0.592 |
|
| 2010 |
Bonazzi S, Barbaras D, Patiny L, Scopelliti R, Schneider P, Cole ST, Kaiser M, Brun R, Gademann K. Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation. Bioorganic & Medicinal Chemistry. 18: 1464-76. PMID 20133138 DOI: 10.1016/J.Bmc.2010.01.013 |
0.322 |
|
| 2010 |
Bonazzi S, Eidam O, Güttinger S, Wach JY, Zemp I, Kutay U, Gademann K. Anguinomycins and derivatives: total syntheses, modeling, and biological evaluation of the inhibition of nucleocytoplasmic transport. Journal of the American Chemical Society. 132: 1432-42. PMID 20055390 DOI: 10.1021/Ja9097093 |
0.348 |
|
| 2010 |
Jana CK, Scopelliti R, Gademann K. Connecting C19 norditerpenoids to C20 diterpenes: Total syntheses of 6-Hydroxy-5,6-dehydrosugiol, 6-Hydroxysugiol, and taiwaniaquinone H, and formal synthesis of dichroanone Synthesis. 2223-2232. DOI: 10.1055/S-0029-1218806 |
0.353 |
|
| 2010 |
Bonazzi S, Binaghi M, Fellay C, Wach JY, Gademann K. Synthetic studies on the sporolides: Exploration of the Enediyne route Synthesis. 631-642. DOI: 10.1055/S-0029-1218608 |
0.345 |
|
| 2010 |
Gademann K, Chavez DE, Jacobsen EN. ChemInform Abstract: Highly Enantioselective Inverse-Electron-Demand Hetero-Diels-Alder Reactions of α,β-Unsaturated Aldehydes. Cheminform. 33: no-no. DOI: 10.1002/chin.200251144 |
0.568 |
|
| 2010 |
Jessen HJ, Gademann K. Totalsynthese des marinen Alkaloids Palau’amin† Angewandte Chemie. 122: 3034-3036. DOI: 10.1002/Ange.201000479 |
0.513 |
|
| 2009 |
Jessen HJ, Barbaras D, Hamburger M, Gademann K. Total synthesis and neuritotrophic activity of farinosone C and derivatives. Organic Letters. 11: 3446-9. PMID 19586047 DOI: 10.1021/Ol901277Q |
0.603 |
|
| 2009 |
Gademann K, Kobylinska J. Antimalarial natural products of marine and freshwater origin. Chemical Record (New York, N.Y.). 9: 187-98. PMID 19424997 DOI: 10.1002/Tcr.200900001 |
0.336 |
|
| 2009 |
Gademann K, Kobylinska J, Wach JY, Woods TM. Surface modifications based on the cyanobacterial siderophore anachelin: from structure to functional biomaterials design. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 22: 595-604. PMID 19350397 DOI: 10.1007/S10534-009-9234-3 |
0.309 |
|
| 2009 |
Portmann C, Prestinari C, Myers T, Scharte J, Gademann K. Directed biosynthesis of phytotoxic alkaloids in the cyanobacterium Nostoc 78-12A. Chembiochem : a European Journal of Chemical Biology. 10: 889-95. PMID 19263450 DOI: 10.1002/Cbic.200800837 |
0.317 |
|
| 2009 |
Portmann C, Blom JF, Kaiser M, Brun R, Jüttner F, Gademann K. New antiplasmodial natural products from cyanobacteria: linking their ecological role to their therapeutic potential Planta Medica. 75. DOI: 10.1055/S-0029-1234265 |
0.351 |
|
| 2009 |
Wach JY, Gademann K. Enantioselective synthesis of the sporolide quinone acid fragment Synlett. 2849-2851. DOI: 10.1055/S-0029-1217963 |
0.321 |
|
| 2009 |
Becher PG, Baumann HI, Gademann K, Jüttner F. The cyanobacterial alkaloid nostocarboline: An inhibitor of acetylcholinesterase and trypsin Journal of Applied Phycology. 21: 103-110. DOI: 10.1007/S10811-008-9335-3 |
0.305 |
|
| 2008 |
Portmann C, Blom JF, Kaiser M, Brun R, Jüttner F, Gademann K. Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from Microcystis aeruginosa PCC 7806 and their antiparasite evaluation. Journal of Natural Products. 71: 1891-6. PMID 18973386 DOI: 10.1021/Np800409Z |
0.336 |
|
| 2008 |
Portmann C, Blom JF, Gademann K, Jüttner F. Aerucyclamides A and B: isolation and synthesis of toxic ribosomal heterocyclic peptides from the cyanobacterium Microcystis aeruginosa PCC 7806. Journal of Natural Products. 71: 1193-6. PMID 18558743 DOI: 10.1021/Np800118G |
0.311 |
|
| 2008 |
Gademann K, Portmann C. Secondary metabolites from cyanobacteria: Complex structures and powerful bioactivities Current Organic Chemistry. 12: 326-341. DOI: 10.2174/138527208783743750 |
0.332 |
|
| 2008 |
Lawrence AK, Gademann K. Aza-annulation strategies in alkaloid total synthesis Synthesis. 0331-0351. DOI: 10.1055/S-2008-1032134 |
0.354 |
|
| 2007 |
Bonazzi S, Güttinger S, Zemp I, Kutay U, Gademann K. Total synthesis, configuration, and biological evaluation of anguinomycin C. Angewandte Chemie (International Ed. in English). 46: 8707-10. PMID 17918172 DOI: 10.1002/Anie.200703134 |
0.358 |
|
| 2007 |
Gademann K, Bethuel Y, Locher HH, Hubschwerlen C. Biomimetic total synthesis and antimicrobial evaluation of anachelin H. The Journal of Organic Chemistry. 72: 8361-70. PMID 17902695 DOI: 10.1021/Jo701402B |
0.335 |
|
| 2007 |
Gademann K, Bonazzi S. Total synthesis of complex cyanobacterial alkaloids without using protecting groups. Angewandte Chemie (International Ed. in English). 46: 5656-8. PMID 17591734 DOI: 10.1002/Anie.200701881 |
0.342 |
|
| 2007 |
Gademann K. Cyanobacterial natural products for the inhibition of biofilm formation and biofouling Chimia. 61: 373-377. DOI: 10.2533/Chimia.2007.373 |
0.317 |
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| 2006 |
Blom JF, Brütsch T, Barbaras D, Bethuel Y, Locher HH, Hubschwerlen C, Gademann K. Potent algicides based on the cyanobacterial alkaloid nostocarboline. Organic Letters. 8: 737-40. PMID 16468755 DOI: 10.1021/Ol052968B |
0.347 |
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| 2006 |
Gademann K. Natural product hybrids Chimia. 60: 841-845. DOI: 10.2533/Chimia.2006.841 |
0.351 |
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| 2006 |
Bethuel Y, Gademann K. Stereoselective total synthesis of (-)-galantinic acid Synlett. 1580-1582. DOI: 10.1055/S-2006-941602 |
0.361 |
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| 2005 |
Becher PG, Beuchat J, Gademann K, Jüttner F. Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A. Journal of Natural Products. 68: 1793-5. PMID 16378379 DOI: 10.1021/Np050312L |
0.301 |
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| 2005 |
Gademann K. Mechanistic studies on the tyrosinase-catalyzed formation of the anachelin chromophore. Chembiochem : a European Journal of Chemical Biology. 6: 913-9. PMID 15825154 DOI: 10.1002/Cbic.200400343 |
0.347 |
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| 2004 |
Gademann K, Bethuel Y. Total synthesis of anachelin H. Organic Letters. 6: 4707-10. PMID 15575666 DOI: 10.1021/Ol048068X |
0.353 |
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| 2004 |
Gademann K, Bethuel Y. A biomimetic route to the peptide alkaloid anachelin. Angewandte Chemie (International Ed. in English). 43: 3327-9. PMID 15213965 DOI: 10.1002/Anie.200453909 |
0.343 |
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| 2004 |
Gademann K, Budzikiewicz H. The peptide alkaloid anachelin: NMR spectroscopic evidence for β-turn formation in aqueous solution Chimia. 58: 212-214. DOI: 10.2533/000942904777677966 |
0.311 |
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| 2003 |
Gademann K, Häne A, Rueping M, Jaun B, Seebach D. The fourth helical secondary structure of beta-peptides: the (P)-28-helix of a beta-hexapeptide consisting of (2R,3S)-3-amino-2-hydroxy acid residues. Angewandte Chemie (International Ed. in English). 42: 1534-7. PMID 12698493 DOI: 10.1002/Anie.200250290 |
0.559 |
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| 2003 |
Gademann K, Häne A, Rueping M, Jaun B, Seebach D. Die vierte helicale Sekundärstruktur von β-Peptiden: (P)-28-Helix eines β-Hexapeptids aus (2R,3S)-3-Amino-2-hydroxycarbonsäure-Einheiten Angewandte Chemie. 115: 1573-1575. DOI: 10.1002/Ange.200250290 |
0.525 |
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| 2002 |
Gademann K, Chavez DE, Jacobsen EN. Highly enantioselective inverse-electron-demand hetero-diels-alder reactions of alpha,beta-unsaturated aldehydes. Angewandte Chemie (International Ed. in English). 41: 3059-61. PMID 12203458 DOI: 10.1002/1521-3773(20020816)41:16<3059::Aid-Anie3059>3.0.Co;2-I |
0.682 |
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| 2002 |
Gademann K, Chavez DE, Jacobsen EN. Highly Enantioselective Inverse-Electron-Demand Hetero-DielsâAlder Reactions of α,β-Unsaturated Aldehydes This work was supported by the NIH (GM-59316), with additional support from the Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung (postdoctoral fellowship to K.G.), and the National Science Foundation (predoctoral fellowship to D.E.C.). We are grateful to Dr. R. Staples for carrying out the X-ray crystal structure analysis of 1. Angewandte Chemie. 114: 3059. DOI: 10.1002/1521-3757(20020816)114:16<3185::Aid-Ange3185>3.0.Co;2-S |
0.469 |
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| 2001 |
Daura X, Gademann K, Schäfer H, Jaun B, Seebach D, van Gunsteren WF. The beta-peptide hairpin in solution: conformational study of a beta-hexapeptide in methanol by NMR spectroscopy and MD simulation. Journal of the American Chemical Society. 123: 2393-404. PMID 11456889 DOI: 10.1021/Ja003689G |
0.409 |
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| 2001 |
Gademann K, Kimmerlin T, Hoyer D, Seebach D. Peptide folding induces high and selective affinity of a linear and small beta-peptide to the human somatostatin receptor 4. Journal of Medicinal Chemistry. 44: 2460-8. PMID 11448228 DOI: 10.1021/Jm010816Q |
0.42 |
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| 2001 |
Gademann K, Seebach D. Synthesis of cyclo-β-tripeptides and their biological in vitro evaluation as antiproliferatives against the growth of human cancer cell lines Helvetica Chimica Acta. 84: 2924-2937. DOI: 10.1002/1522-2675(20011017)84:10<2924::Aid-Hlca2924>3.0.Co;2-E |
0.421 |
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| 2000 |
Seebach D, Jacobi A, Rueping M, Gademann K, Ernst M, Jaun B. Synthesis of β-hexa- and β-heptapeptides containing novel β 2,3-amino acids with two serine or two cysteine side chains - CD- and NMR-spectroscopic evidence for 3 14-helical secondary structures in water Helvetica Chimica Acta. 83: 2115-2140. DOI: 10.1002/1522-2675(20000906)83:9<2115::Aid-Hlca2115>3.0.Co;2-E |
0.564 |
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| 2000 |
Gademann K, Ernst M, Seebach D, Hoyer D. The cyclo-β-tetrapeptide (β-HPhe-β-HThr-β-HLys-β-HTrp): Synthesis, NMR structure in methanol solution, and affinity for human somatostatin receptors Helvetica Chimica Acta. 83: 16-33. DOI: 10.1002/(Sici)1522-2675(20000119)83:1<16::Aid-Hlca16>3.0.Co;2-3 |
0.43 |
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| 1999 |
Gademann K, Ernst M, Hoyer D, Seebach D. Synthesis and Biological Evaluation of a Cyclo-β-tetrapeptide as a Somatostatin Analogue. Angewandte Chemie (International Ed. in English). 38: 1223-1226. PMID 29711729 DOI: 10.1002/(Sici)1521-3773(19990503)38:9<1223::Aid-Anie1223>3.0.Co;2-A |
0.431 |
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| 1999 |
Seebach D, Abele S, Gademann K, Jaun B. Pleated Sheets and Turns of β-Peptides with Proteinogenic Side Chains. Angewandte Chemie (International Ed. in English). 38: 1595-1597. PMID 29710979 DOI: 10.1002/(Sici)1521-3773(19990601)38:11<1595::Aid-Anie1595>3.0.Co;2-0 |
0.41 |
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| 1999 |
Sifferlen T, Rueping M, Gademann K, Jaun B, Seebach D. β-thiopeptides: Synthesis, NMR solution structure, CD spectra and photochemistry Helvetica Chimica Acta. 82: 2067-2093. DOI: 10.1002/(Sici)1522-2675(19991215)82:12<2067::Aid-Hlca2067>3.0.Co;2-5 |
0.55 |
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| 1999 |
Gademann K, Seebach D. Preparation and NMR structure of the cyclo-β-tripeptide [β3-HGlu]3 in aqueous solution: A new class of enterobactin-type C3-symmetrical ligands? Helvetica Chimica Acta. 82: 957-962. DOI: 10.1002/(Sici)1522-2675(19990609)82:6<957::Aid-Hlca957>3.0.Co;2-H |
0.443 |
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| 1999 |
Gademann K, Jaun B, Seebach D, Perozzo R, Scapozza L, Folkers G. Temperature-dependent NMR and CD spectra of β-peptides: On the thermal stability of β-peptide helices - Is the folding process of β-peptides non- cooperative? Helvetica Chimica Acta. 82: 1-11. DOI: 10.1002/(Sici)1522-2675(19990113)82:1<1::Aid-Hlca1>3.0.Co;2-N |
0.423 |
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| 1999 |
Daura X, Gademann K, Jaun B, Seebach D, van Gunsteren WF, Mark AE. Peptide Folding: When Simulation Meets Experiment Angewandte Chemie International Edition. 38: 236-240. DOI: 10.1002/(Sici)1521-3773(19990115)38:1/2<236::Aid-Anie236>3.0.Co;2-M |
0.377 |
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| 1999 |
Seebach D, Abele S, Gademann K, Jaun B. Faltblätter und Schleifen von β-Peptiden mit proteinogenen Seitenketten Angewandte Chemie. 111: 1700-1703. DOI: 10.1002/(Sici)1521-3757(19990601)111:11<1700::Aid-Ange1700>3.0.Co;2-M |
0.389 |
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| 1999 |
Gademann K, Ernst M, Hoyer D, Seebach D. Synthese und biologische Evaluation eines Cyclo-β-tetrapeptids als Somatostatin-Analogon Angewandte Chemie. 111: 1302-1304. DOI: 10.1002/(Sici)1521-3757(19990503)111:9<1302::Aid-Ange1302>3.0.Co;2-L |
0.392 |
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| 1999 |
Daura X, Gademann K, Jaun B, Seebach D, van Gunsteren WF, Mark AE. Peptidfaltung: Wenn die Simulation das Experiment erreicht Angewandte Chemie. 111: 249-253. DOI: 10.1002/(Sici)1521-3757(19990115)111:1/2<249::Aid-Ange249>3.0.Co;2-B |
0.4 |
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| 1998 |
Matthews JL, Gademann K, Jaun B, Seebach D. Linear and cyclic β3-oligopeptides with functionalised side-chains (-CH2OBn, -CO2Bn, -CH2CH2CO2Bn) derived from serine and from aspartic and glutamic acid Journal of the Chemical Society - Perkin Transactions 1. 3331-3340. DOI: 10.1039/A805478I |
0.419 |
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| 1998 |
Hintermann T, Gademann K, Jaun B, Seebach D. γ‐Peptides Forming More Stable Secondary Structures than α‐Peptides: Synthesis and helical NMR‐solution structure of the γ‐hexapeptide analog of H‐(Val‐Ala‐Leu)2‐OH Helvetica Chimica Acta. 81: 983-1002. DOI: 10.1002/Hlca.19980810514 |
0.427 |
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| 1998 |
Seebach D, Abele S, Gademann K, Guichard G, Hintermann T, Jaun B, Matthews JL, Schreiber JV, Oberer L, Hommel U, Widmer H. ?2- and ?3-Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the influence of solvation and hydrophobic interactions on folding Helvetica Chimica Acta. 81: 932-982. DOI: 10.1002/Hlca.19980810513 |
0.435 |
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| 1997 |
Seebach D, Gademann K, Schreiber JV, Matthews JL, Hintermann T, Jaun B, Oberer L, Hommel U, Widmer H. ‘Mixed’ β-peptides: A unique helical secondary structure in solution. Preliminary communication Helvetica Chimica Acta. 80: 2033-2038. DOI: 10.1002/Hlca.19970800703 |
0.415 |
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