Year |
Citation |
Score |
2022 |
Abrahamsson D, Siddharth A, Robinson JF, Soshilov A, Elmore S, Cogliano V, Ng C, Khan E, Ashton R, Chiu WA, Fung J, Zeise L, Woodruff TJ. Modeling the transplacental transfer of small molecules using machine learning: a case study on per- and polyfluorinated substances (PFAS). Journal of Exposure Science & Environmental Epidemiology. PMID 36207486 DOI: 10.1038/s41370-022-00481-2 |
0.55 |
|
2022 |
Kallimanis P, Chinou I, Panagiotopoulou A, Soshilov AA, He G, Denison MS, Magiatis P. L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer. Molecules (Basel, Switzerland). 27. PMID 35458697 DOI: 10.3390/molecules27082499 |
0.604 |
|
2020 |
Soshilov AA, Motta S, Bonati L, Denison MS. Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form. International Journal of Molecular Sciences. 21. PMID 32252465 DOI: 10.3390/Ijms21072474 |
0.65 |
|
2019 |
Hawerkamp HC, Kislat A, Gerber PA, Pollet M, Rolfes KM, Soshilov AA, Denison MS, Momin AA, Arold ST, Datsi A, Braun SA, Oláh P, Lacouture ME, Krutmann J, Haarmann-Stemmann T, et al. Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events. Allergy. PMID 31269229 DOI: 10.1111/All.13972 |
0.521 |
|
2018 |
Corre S, Tardif N, Mouchet N, Leclair HM, Boussemart L, Gautron A, Bachelot L, Perrot A, Soshilov A, Rogiers A, Rambow F, Dumontet E, Tarte K, Bessede A, Guillemin GJ, et al. Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma. Nature Communications. 9: 4775. PMID 30429474 DOI: 10.1038/S41467-018-06951-2 |
0.562 |
|
2018 |
Faber SC, Soshilov AA, Giani Tagliabue S, Bonati L, Denison MS. Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist. International Journal of Molecular Sciences. 19. PMID 30201897 DOI: 10.3390/Ijms19092692 |
0.692 |
|
2018 |
Hawerkamp H, Kislat A, Gerber P, Pollet M, Soshilov A, Denison M, Momin A, Arold S, Datsi A, Braun S, Lacouture M, Haarmann-Stemmann T, Homey B, Meller S. 1057 Vemurafenib acts as an aryl hydrocarbon receptor antagonist Journal of Investigative Dermatology. 138: S179. DOI: 10.1016/J.Jid.2018.03.1070 |
0.57 |
|
2017 |
Elshenawy OH, Abdelhamid G, Soshilov AA, Denison MS, El-Kadi AO. DOWN-REGULATION OF CYTOCHROME P450 1A1 BY MONOMETHYLARSONOUS ACID IN HUMAN HEPG2 CELLS. Toxicology Letters. PMID 28189647 DOI: 10.1016/J.Toxlet.2017.02.012 |
0.616 |
|
2016 |
Cheng Y, Jin UH, Davidson LA, Chapkin RS, Jayaraman A, Tamamis P, Orr A, Allred C, Denison MS, Soshilov A, Weaver E, Safe S. Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27837168 DOI: 10.1093/Toxsci/Kfw230 |
0.634 |
|
2016 |
Corrada D, Soshilov AA, Denison MS, Bonati L. Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation. Plos Computational Biology. 12: e1004981. PMID 27295348 DOI: 10.1371/Journal.Pcbi.1004981 |
0.624 |
|
2016 |
Bak SM, Iida M, Soshilov AA, Denison MS, Iwata H, Kim EY. Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major). Archives of Toxicology. PMID 27188387 DOI: 10.1007/S00204-016-1732-9 |
0.593 |
|
2015 |
Mexia N, Gaitanis G, Velegraki A, Soshilov A, Denison MS, Magiatis P. Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast. Archives of Biochemistry and Biophysics. 571: 16-20. PMID 25721496 DOI: 10.1016/J.Abb.2015.02.023 |
0.633 |
|
2015 |
Maayah ZH, Ghebeh H, Alhaider AA, El-Kadi AO, Soshilov AA, Denison MS, Ansari MA, Korashy HM. Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway. Toxicology and Applied Pharmacology. 284: 217-26. PMID 25697376 DOI: 10.1016/J.Taap.2015.02.007 |
0.586 |
|
2015 |
Frauenstein K, Tigges J, Soshilov AA, Kado S, Raab N, Fritsche E, Haendeler J, Denison MS, Vogel CF, Haarmann-Stemmann T. Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2). Archives of Toxicology. 89: 1329-36. PMID 25082669 DOI: 10.1007/S00204-014-1321-8 |
0.647 |
|
2014 |
Novotna A, Korhonova M, Bartonkova I, Soshilov AA, Denison MS, Bogdanova K, Kolar M, Bednar P, Dvorak Z. Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. Plos One. 9: e101832. PMID 25000292 DOI: 10.1371/Journal.Pone.0101832 |
0.687 |
|
2014 |
Soshilov AA, Denison MS. Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed mutagenesis. Molecular and Cellular Biology. 34: 1707-19. PMID 24591650 DOI: 10.1128/Mcb.01183-13 |
0.675 |
|
2014 |
Anwar-Mohamed A, Elshenawy OH, Soshilov AA, Denison MS, Chris Le X, Klotz LO, El-Kadi AO. Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms. Free Radical Biology & Medicine. 67: 171-87. PMID 24161444 DOI: 10.1016/J.Freeradbiomed.2013.10.810 |
0.615 |
|
2014 |
Soshilov AA, Denison MS. DNA binding (gel retardation assay) analysis for identification of aryl hydrocarbon (Ah) receptor agonists and antagonists Methods in Pharmacology and Toxicology. 207-219. DOI: 10.1007/978-1-62703-742-6-12 |
0.618 |
|
2013 |
Hu Q, He G, Zhao J, Soshilov A, Denison MS, Zhang A, Yin H, Fraccalvieri D, Bonati L, Xie Q, Zhao B. Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. Plos One. 8: e66258. PMID 23776647 DOI: 10.1371/Journal.Pone.0066258 |
0.684 |
|
2013 |
Brennan JC, Denison MS, Holstege DM, Magiatis P, Dallas JL, Gutierrez EG, Soshilov AA, Millam JR. 2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines. Bmc Complementary and Alternative Medicine. 13: 133. PMID 23768005 DOI: 10.1186/1472-6882-13-133 |
0.577 |
|
2013 |
Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Zapletalova M, Anzenbacher P, Dvorak Z. Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicology Letters. 221: 1-8. PMID 23735880 DOI: 10.1016/J.Toxlet.2013.05.007 |
0.638 |
|
2013 |
Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Anzenbacher P, Dvorak Z. Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicology Letters. 218: 253-9. PMID 23419638 DOI: 10.1016/J.Toxlet.2013.01.020 |
0.657 |
|
2013 |
Fraccalvieri D, Soshilov AA, Karchner SI, Franks DG, Pandini A, Bonati L, Hahn ME, Denison MS. Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor. Biochemistry. 52: 714-25. PMID 23286227 DOI: 10.1021/Bi301457F |
0.672 |
|
2012 |
Tiong CT, Chen C, Zhang SJ, Li J, Soshilov A, Denison MS, Lee LS, Tam VH, Wong SP, Xu HE, Yong EL. A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein. Carcinogenesis. 33: 1089-97. PMID 22345291 DOI: 10.1093/Carcin/Bgs110 |
0.576 |
|
2012 |
El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 353-62. PMID 22037238 DOI: 10.1016/J.Fct.2011.10.052 |
0.662 |
|
2012 |
El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO. Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol. Toxicology Letters. 208: 51-61. PMID 22001777 DOI: 10.1016/J.Toxlet.2011.09.030 |
0.665 |
|
2011 |
Motto I, Bordogna A, Soshilov AA, Denison MS, Bonati L. New aryl hydrocarbon receptor homology model targeted to improve docking reliability. Journal of Chemical Information and Modeling. 51: 2868-81. PMID 21981577 DOI: 10.1021/Ci2001617 |
0.664 |
|
2011 |
Denison MS, Soshilov AA, He G, DeGroot DE, Zhao B. Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 1-22. PMID 21908767 DOI: 10.1093/Toxsci/Kfr218 |
0.738 |
|
2011 |
Soshilov A, Denison MS. Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domain. The Journal of Biological Chemistry. 286: 35275-82. PMID 21856752 DOI: 10.1074/Jbc.M111.246439 |
0.66 |
|
2011 |
Korashy HM, Anwar-Mohamed A, Soshilov AA, Denison MS, El-Kadi AO. The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation. Chemical Research in Toxicology. 24: 1540-8. PMID 21732638 DOI: 10.1021/Tx200141P |
0.662 |
|
2009 |
Pandini A, Soshilov AA, Song Y, Zhao J, Bonati L, Denison MS. Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. Biochemistry. 48: 5972-83. PMID 19456125 DOI: 10.1021/Bi900259Z |
0.667 |
|
2008 |
Soshilov A, Denison MS. Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 283: 32995-3005. PMID 18806268 DOI: 10.1074/Jbc.M802414200 |
0.628 |
|
2007 |
Pandini A, Denison MS, Song Y, Soshilov AA, Bonati L. Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. Biochemistry. 46: 696-708. PMID 17223691 DOI: 10.1021/Bi061460T |
0.63 |
|
2002 |
Grigorieva E, Soshilov A, Surovtseva Y, Schwartz EL, Duzhak TG, Gulyaeva LF, Lyakhovich VV. Induction of the CYP2B genes by triphenyldioxane treatment in the rat liver. Toxicology in Vitro : An International Journal Published in Association With Bibra. 16: 467-73. PMID 12110287 DOI: 10.1016/S0887-2333(02)00038-3 |
0.328 |
|
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