Parents
Sign in to add mentorJohn Diffley | grad student | (Neurotree) | |
Giovanna Lucchini | grad student | ||
Paolo Plevani | grad student |
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Publications
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Cazzaniga C, Göder A, Rainey MD, et al. (2024) CDC7 inhibition drives an inflammatory response and a p53-dependent senescent-like state in breast epithelial cells. The Febs Journal |
Göder A, Quinlan A, Rainey MD, et al. (2023) PTBP1 enforces ATR-CHK1 signaling determining the potency of CDC7 inhibitors. Iscience. 26: 106951 |
Rainey MD, Bennett D, O'Dea R, et al. (2020) ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition. Cell Reports. 32: 108096 |
Rainey MD, Quinlan A, Cazzaniga C, et al. (2020) CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. Embo Reports. e48920 |
O'Dea R, Santocanale C. (2020) Non-canonical regulation of homologous recombination DNA repair by the USP9X deubiquitinase. Journal of Cell Science |
Rainey MD, Quachthithu H, Gaboriau D, et al. (2017) DNA Replication Dynamics and Cellular Responses to ATP Competitive CDC7 Kinase Inhibitors. Acs Chemical Biology. 12: 1893-1902 |
Wu KZ, Wang GN, Fitzgerald J, et al. (2016) DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach. Nucleic Acids Research |
McGarry E, Gaboriau D, Rainey M, et al. (2016) The deubiquitinase USP9X maintains DNA replication fork stability and DNA damage checkpoint responses by regulating CLASPIN during S-phase. Cancer Research |
O'Connor A, Maffini S, Rainey MD, et al. (2015) Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biology Open |
FitzGerald J, Murillo LS, O'Brien G, et al. (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. Plos One. 9: e98891 |