Corrado Santocanale

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"Corrado Santocanale"

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John Diffley grad student (Neurotree)
Giovanna Lucchini grad student
Paolo Plevani grad student
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Publications

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Cazzaniga C, Göder A, Rainey MD, et al. (2024) CDC7 inhibition drives an inflammatory response and a p53-dependent senescent-like state in breast epithelial cells. The Febs Journal
Göder A, Quinlan A, Rainey MD, et al. (2023) PTBP1 enforces ATR-CHK1 signaling determining the potency of CDC7 inhibitors. Iscience. 26: 106951
Rainey MD, Bennett D, O'Dea R, et al. (2020) ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition. Cell Reports. 32: 108096
Rainey MD, Quinlan A, Cazzaniga C, et al. (2020) CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. Embo Reports. e48920
O'Dea R, Santocanale C. (2020) Non-canonical regulation of homologous recombination DNA repair by the USP9X deubiquitinase. Journal of Cell Science
Rainey MD, Quachthithu H, Gaboriau D, et al. (2017) DNA Replication Dynamics and Cellular Responses to ATP Competitive CDC7 Kinase Inhibitors. Acs Chemical Biology. 12: 1893-1902
Wu KZ, Wang GN, Fitzgerald J, et al. (2016) DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach. Nucleic Acids Research
McGarry E, Gaboriau D, Rainey M, et al. (2016) The deubiquitinase USP9X maintains DNA replication fork stability and DNA damage checkpoint responses by regulating CLASPIN during S-phase. Cancer Research
O'Connor A, Maffini S, Rainey MD, et al. (2015) Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biology Open
FitzGerald J, Murillo LS, O'Brien G, et al. (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. Plos One. 9: e98891
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