Anne Chomyn

California Institute of Technology, Pasadena, CA 
Mitochondrial biogenesis
"Anne Chomyn"


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Giuseppe M. Attardi research scientist 1979-2007 Caltech
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Hashimoto M, Bacman SR, Peralta S, et al. (2015) MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy
Chen A, Raule N, Chomyn A, et al. (2012) Decreased reactive oxygen species production in cells with mitochondrial haplogroups associated with longevity. Plos One. 7: e46473
Chen H, Vermulst M, Wang YE, et al. (2010) Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell. 141: 280-9
Iwata N, Zhang J, Atzmon G, et al. (2007) Aging-related occurrence in Ashkenazi Jews of leukocyte heteroplasmic mtDNA mutation adjacent to replication origin frequently remodeled in Italian centenarians. Mitochondrion. 7: 267-72
Hájek P, Chomyn A, Attardi G. (2007) Identification of a novel mitochondrial complex containing mitofusin 2 and stomatin-like protein 2. The Journal of Biological Chemistry. 282: 5670-81
Duvezin-Caubet S, Jagasia R, Wagener J, et al. (2006) Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology. The Journal of Biological Chemistry. 281: 37972-9
Chen H, Chomyn A, Chan DC. (2005) Disruption of fusion results in mitochondrial heterogeneity and dysfunction. The Journal of Biological Chemistry. 280: 26185-92
Bai Y, Hu P, Park JS, et al. (2004) Genetic and functional analysis of mitochondrial DNA-encoded complex I genes. Annals of the New York Academy of Sciences. 1011: 272-83
Chomyn A, Attardi G. (2003) MtDNA mutations in aging and apoptosis. Biochemical and Biophysical Research Communications. 304: 519-29
Duan S, Hajek P, Lin C, et al. (2003) Mitochondrial outer membrane permeability change and hypersensitivity to digitonin early in staurosporine-induced apoptosis. The Journal of Biological Chemistry. 278: 1346-53
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