| Year |
Citation |
Score |
| 2022 |
Kulkarni AS, Aleksic S, Berger DM, Sierra F, Kuchel GA, Barzilai N. Geroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization. Aging Cell. e13596. PMID 35343051 DOI: 10.1111/acel.13596 |
0.669 |
|
| 2020 |
Kulkarni AS, Peck BD, Walton RG, Kern PA, Mar JC, Windham ST, Bamman MM, Barzilai N, Peterson CA. Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults. Aging. 12. PMID 33071237 DOI: 10.18632/aging.104096 |
0.664 |
|
| 2020 |
Justice JN, Gubbi S, Kulkarni AS, Bartley JM, Kuchel GA, Barzilai N. A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin. Geroscience. PMID 32902818 DOI: 10.1007/s11357-020-00261-6 |
0.655 |
|
| 2020 |
Barzilai N, Appleby JC, Austad SN, Cuervo AM, Kaeberlein M, Gonzalez-Billault C, Lederman S, Stambler I, Sierra F. Geroscience in the Age of COVID-19. Aging and Disease. 11: 725-729. PMID 32765937 DOI: 10.14336/Ad.2020.0629 |
0.31 |
|
| 2020 |
Sathyan S, Ayers E, Gao T, Milman S, Barzilai N, Verghese J. Plasma proteomic profile of frailty. Aging Cell. e13193. PMID 32762010 DOI: 10.1111/Acel.13193 |
0.301 |
|
| 2020 |
Zhang WB, Aleksic S, Gao T, Weiss EF, Demetriou E, Verghese J, Holtzer R, Barzilai N, Milman S. Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults. Cells. 9. PMID 32492897 DOI: 10.3390/Cells9061368 |
0.351 |
|
| 2020 |
Kulkarni AS, Gubbi S, Barzilai N. Benefits of Metformin in Attenuating the Hallmarks of Aging. Cell Metabolism. PMID 32333835 DOI: 10.1016/J.Cmet.2020.04.001 |
0.694 |
|
| 2020 |
Rozanov L, Ravichandran M, Grigolon G, Zanellati MC, Mansfeld J, Zarse K, Barzilai N, Atzmon G, Fischer F, Ristow M. Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A. Redox Biology. 32: 101448. PMID 32203922 DOI: 10.1016/J.Redox.2020.101448 |
0.368 |
|
| 2019 |
Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T. Undulating changes in human plasma proteome profiles across the lifespan. Nature Medicine. 25: 1843-1850. PMID 31806903 DOI: 10.1038/S41591-019-0673-2 |
0.367 |
|
| 2019 |
Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, et al. Latest advances in aging research and drug discovery. Aging. 11. PMID 31770722 DOI: 10.18632/Aging.102487 |
0.329 |
|
| 2019 |
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, ... ... Barzilai N, et al. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications. 10: 3669. PMID 31413261 DOI: 10.1038/S41467-019-11558-2 |
0.33 |
|
| 2019 |
Newman JC, Sokoloski JL, Robbins PD, Niedernhofer LJ, Reed MJ, Wei J, Austad SN, Barzilai N, Cohen HJ, Kuchel GA, Kirkland JL, Pignolo RJ. Creating the Next Generation of Translational Geroscientists. Journal of the American Geriatrics Society. PMID 31287934 DOI: 10.1111/Jgs.16055 |
0.303 |
|
| 2019 |
Hurria A, Carpenter CR, McFarland F, Lundebjerg NE, de Cabo R, Ferrucci L, Studenski SA, Barzilai N, Briggs JP, Ix JH, Kitzman DW, Kuchel GA, Musi N, Newman JC, Rando TA, et al. Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series. Journal of the American Geriatrics Society. PMID 30693953 DOI: 10.1111/Jgs.15788 |
0.341 |
|
| 2019 |
Fleming GA, Zhao JH, Seoh TC, Barzilai N. A Regulatory Pathway for Medicines That Target Aging Public Policy & Aging Report. 29: 128-133. DOI: 10.1093/Ppar/Prz018 |
0.309 |
|
| 2019 |
Justice JN, Kuchel GA, Barzilai N, Kritchevsky S. BIOMARKER STRATEGIES FOR GEROSCIENCE-GUIDED CLINICAL TRIALS Innovation in Aging. 3: S745-S746. DOI: 10.1093/Geroni/Igz038.2731 |
0.331 |
|
| 2019 |
Kulkarni AS, Mar JC, Barzilai N. INVESTIGATING DYNAMICS OF AGE-ASSOCIATED TRANSCRIPTIONAL NETWORKS WITH INTERVENTIONS TARGETING AGING Innovation in Aging. 3: S559-S559. DOI: 10.1093/Geroni/Igz038.2066 |
0.694 |
|
| 2018 |
Walters RO, Arias E, Diaz A, Burgos ES, Guan F, Tiano S, Mao K, Green CL, Qiu Y, Shah H, Wang D, Hudgins AD, Tabrizian T, Tosti V, Shechter D, ... ... Barzilai N, et al. Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans. Cell Reports. 25: 663-676.e6. PMID 30332646 DOI: 10.1016/J.Celrep.2018.09.065 |
0.373 |
|
| 2018 |
Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, et al. APOE Alleles and Extreme Human Longevity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30060062 DOI: 10.1093/Gerona/Gly174 |
0.339 |
|
| 2018 |
Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, Li P, Allison DB, Salimi-Moosavi H, Beltran PJ, Cohen P, ... Barzilai N, et al. Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. Nature Communications. 9: 2394. PMID 29921922 DOI: 10.1038/S41467-018-04805-5 |
0.35 |
|
| 2018 |
Sathyan S, Barzilai N, Atzmon G, Milman S, Ayers E, Verghese J. Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. Frontiers in Medicine. 5: 105. PMID 29765957 DOI: 10.3389/Fmed.2018.00105 |
0.323 |
|
| 2018 |
Gubbi S, Quipildor GF, Barzilai N, Huffman DM, Milman S. IGF-1: The Jekyll & Hyde of the aging brain. Journal of Molecular Endocrinology. PMID 29739805 DOI: 10.1530/Jme-18-0093 |
0.356 |
|
| 2018 |
Kulkarni AS, Brutsaert EF, Anghel V, Zhang K, Bloomgarden N, Pollak M, Mar JC, Hawkins M, Crandall JP, Barzilai N. Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. Aging Cell. PMID 29383869 DOI: 10.1111/Acel.12723 |
0.786 |
|
| 2018 |
Barzilai N. HOW TO PROVE THAT AGING CAN BE TAMED AND THAT APPROPRIATE REGULATION CAN BE FOLLOWED? Innovation in Aging. 2: 544-544. DOI: 10.1093/Geroni/Igy023.2008 |
0.326 |
|
| 2017 |
Knight CM, Gutierrez-Juarez R, Lam TKT, Arrieta-Cruz I, Huang L, Schwartz G, Barzilai N, Rossetti L. Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes. 66: 3143-3144. PMID 29162736 DOI: 10.2337/Db17-Er12C |
0.328 |
|
| 2017 |
Martinez-Lopez N, Tarabra E, Toledo M, Garcia-Macia M, Sahu S, Coletto L, Batista-Gonzalez A, Barzilai N, Pessin JE, Schwartz GJ, Kersten S, Singh R. System-wide Benefits of Intermeal Fasting by Autophagy. Cell Metabolism. PMID 29107505 DOI: 10.1016/J.Cmet.2017.09.020 |
0.358 |
|
| 2017 |
Ben-Avraham D, Govindaraju DR, Budagov T, Fradin D, Durda P, Liu B, Ott S, Gutman D, Sharvit L, Kaplan R, Bougnères P, Reiner A, Shuldiner AR, Cohen P, Barzilai N, et al. The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. Science Advances. 3: e1602025. PMID 28630896 DOI: 10.1126/Sciadv.1602025 |
0.332 |
|
| 2017 |
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Barzilai N, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329 |
0.4 |
|
| 2017 |
Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, et al. Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28329397 DOI: 10.1093/Gerona/Glx041 |
0.758 |
|
| 2016 |
Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, ... ... Barzilai N, et al. Disease drivers of aging. Annals of the New York Academy of Sciences. 1386: 45-68. PMID 27943360 DOI: 10.1111/Nyas.13299 |
0.323 |
|
| 2016 |
Huffman DM, Justice JN, Stout MB, Kirkland JL, Barzilai N, Austad SN. Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27535967 DOI: 10.1093/Gerona/Glw106 |
0.316 |
|
| 2016 |
Justice J, Miller JD, Newman JC, Hashmi SK, Halter J, Austad SN, Barzilai N, Kirkland JL. Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27535966 DOI: 10.1093/Gerona/Glw126 |
0.31 |
|
| 2016 |
Heo HJ, Tozour JN, Delahaye F, Zhao Y, Cui L, Barzilai N, Einstein FH. Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition. Aging Cell. PMID 27470058 DOI: 10.1111/Acel.12505 |
0.369 |
|
| 2016 |
Barzilai N, Crandall JP, Kritchevsky SB, Espeland MA. Metformin as a Tool to Target Aging. Cell Metabolism. 23: 1060-5. PMID 27304507 DOI: 10.1016/J.Cmet.2016.05.011 |
0.34 |
|
| 2016 |
Milman S, Huffman DM, Barzilai N. The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research. Cell Metabolism. 23: 980-9. PMID 27304500 DOI: 10.1016/J.Cmet.2016.05.014 |
0.396 |
|
| 2016 |
Marzec M, Hawkes CP, Eletto D, Boyle S, Rosenfeld R, Hwa V, Wit JM, van Duyvenvoorde HA, Oostdijk W, Losekoot M, Pedersen O, Beng Yeap B, Flicker L, Barzilai N, Atzmon G, et al. A human variant of Glucose-regulated protein 94 that inefficiently supports IGF production. Endocrinology. en20152058. PMID 26982636 DOI: 10.1210/En.2015-2058 |
0.359 |
|
| 2016 |
Milman S, Barzilai N. Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span. Cold Spring Harbor Perspectives in Medicine. 6: a025098. PMID 26637439 DOI: 10.1101/Cshperspect.A025098 |
0.373 |
|
| 2015 |
Fortney K, Dobriban E, Garagnani P, Pirazzini C, Monti D, Mari D, Atzmon G, Barzilai N, Franceschi C, Owen AB, Kim SK. Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity. Plos Genetics. 11: e1005728. PMID 26677855 DOI: 10.1371/Journal.Pgen.1005728 |
0.319 |
|
| 2015 |
Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N. Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline. Aging Cell. PMID 26534869 DOI: 10.1111/Acel.12415 |
0.459 |
|
| 2015 |
Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, et al. Interventions to Slow Aging in Humans: Are We Ready? Aging Cell. 14: 497-510. PMID 25902704 DOI: 10.1111/Acel.12338 |
0.337 |
|
| 2015 |
Han J, Atzmon G, Barzilai N, Suh Y. Genetic variation in Sirtuin 1 (SIRT1) is associated with lipid profiles but not with longevity in Ashkenazi Jews. Translational Research : the Journal of Laboratory and Clinical Medicine. 165: 480-1. PMID 25305471 DOI: 10.1016/J.Trsl.2014.09.008 |
0.327 |
|
| 2014 |
Ayers E, Barzilai N, Crandall JP, Milman S, Verghese J. Association of exceptional parental longevity and physical function in aging. Age (Dordrecht, Netherlands). 36: 9677. PMID 24997018 DOI: 10.1007/S11357-014-9677-5 |
0.303 |
|
| 2014 |
Eny KM, Lutgers HL, Maynard J, Klein BE, Lee KE, Atzmon G, Monnier VM, van Vliet-Ostaptchouk JV, Graaff R, van der Harst P, Snieder H, van der Klauw MM, Sell DR, Hosseini SM, Cleary PA, ... ... Barzilai N, et al. GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Diabetologia. 57: 1623-34. PMID 24934506 DOI: 10.1007/S00125-014-3286-9 |
0.317 |
|
| 2014 |
Milman S, Atzmon G, Huffman DM, Wan J, Crandall JP, Cohen P, Barzilai N. Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity. Aging Cell. 13: 769-71. PMID 24618355 DOI: 10.1111/Acel.12213 |
0.314 |
|
| 2014 |
Kolovou G, Barzilai N, Caruso C, Sikora E, Capri M, Tzanetakou IP, Bilianou H, Avery P, Katsiki N, Panotopoulos G, Franceschi C, Benetos A, Mikhailidis DP. The challenges in moving from ageing to successful longevity. Current Vascular Pharmacology. 12: 662-73. PMID 24350930 DOI: 10.2174/1570161111666131219095114 |
0.344 |
|
| 2014 |
Avery P, Barzilai N, Benetos A, Bilianou H, Capri M, Caruso C, Franceschi C, Katsiki N, Mikhailidis DP, Panotopoulos G, Sikora E, Tzanetakou IP, Kolovou G. Ageing, longevity, exceptional longevity and related genetic and non genetics markers: panel statement. Current Vascular Pharmacology. 12: 659-61. PMID 24350929 DOI: 10.2174/1570161111666131219101226 |
0.338 |
|
| 2014 |
Milman S, Atzmon G, Crandall J, Barzilai N. Phenotypes and genotypes of high density lipoprotein cholesterol in exceptional longevity. Current Vascular Pharmacology. 12: 690-7. PMID 24350928 DOI: 10.2174/1570161111666131219101551 |
0.34 |
|
| 2014 |
Chang AL, Atzmon G, Bergman A, Brugmann S, Atwood SX, Chang HY, Barzilai N. Identification of genes promoting skin youthfulness by genome-wide association study. The Journal of Investigative Dermatology. 134: 651-7. PMID 24037343 DOI: 10.1038/Jid.2013.381 |
0.304 |
|
| 2013 |
Kuliawat R, Klein L, Gong Z, Nicoletta-Gentile M, Nemkal A, Cui L, Bastie C, Su K, Huffman D, Surana M, Barzilai N, Fleischer N, Muzumdar R. Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4890-8. PMID 23995290 DOI: 10.1096/Fj.13-231092 |
0.422 |
|
| 2013 |
Verghese J, Holtzer R, Wang C, Katz MJ, Barzilai N, Lipton RB. Role of APOE genotype in gait decline and disability in aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 1395-401. PMID 23902934 DOI: 10.1093/Gerona/Glt115 |
0.32 |
|
| 2013 |
Crandall JP, Barzilai N. Exploring the promise of resveratrol: where do we go from here? Diabetes. 62: 1022-3. PMID 23520278 DOI: 10.2337/Db12-1788 |
0.426 |
|
| 2013 |
Han J, Ryu S, Moskowitz DM, Rothenberg D, Leahy DJ, Atzmon G, Barzilai N, Suh Y. Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing. Mechanisms of Ageing and Development. 134: 478-85. PMID 23376243 DOI: 10.1016/J.Mad.2013.01.005 |
0.317 |
|
| 2013 |
Heo H, Huffman D, Delahaye F, Karakash S, Zhao Y, Barzilai N, Einstein F. 51: Moderate voluntary running protects against hepatic insulin resistance and restores the placenta-pup glucose uptake gradient in diet-induced obese pregnant rats American Journal of Obstetrics and Gynecology. 208: S30-S31. DOI: 10.1016/J.Ajog.2012.10.225 |
0.395 |
|
| 2012 |
Esterson YB, Kishore P, Koppaka S, Li W, Zhang K, Tonelli J, Lee DE, Kehlenbrink S, Lawrence S, Crandall J, Barzilai N, Hawkins M. Fatty acid-induced production of plasminogen activator inhibitor-1 by adipose macrophages is greater in middle-aged versus younger adult participants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1321-8. PMID 23089338 DOI: 10.1093/Gerona/Gls200 |
0.658 |
|
| 2012 |
Barzilai N, Ferrucci L. Insulin resistance and aging: a cause or a protective response? The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1329-31. PMID 22859390 DOI: 10.1093/Gerona/Gls145 |
0.415 |
|
| 2012 |
Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE. The place of genetics in ageing research. Nature Reviews. Genetics. 13: 589-94. PMID 22777128 DOI: 10.1038/Nrg3290 |
0.336 |
|
| 2012 |
Barzilai N, Huffman DM, Muzumdar RH, Bartke A. The critical role of metabolic pathways in aging. Diabetes. 61: 1315-22. PMID 22618766 DOI: 10.2337/Db11-1300 |
0.434 |
|
| 2012 |
Huffman DM, Deelen J, Ye K, Bergman A, Slagboom EP, Barzilai N, Atzmon G. Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1153-60. PMID 22496539 DOI: 10.1093/Gerona/Gls103 |
0.312 |
|
| 2012 |
Conneely KN, Capell BC, Erdos MR, Sebastiani P, Solovieff N, Swift AJ, Baldwin CT, Budagov T, Barzilai N, Atzmon G, Puca AA, Perls TT, Geesaman BJ, Boehnke M, Collins FS. Human longevity and common variations in the LMNA gene: a meta-analysis. Aging Cell. 11: 475-81. PMID 22340368 DOI: 10.1111/J.1474-9726.2012.00808.X |
0.312 |
|
| 2012 |
Crandall JP, Oram V, Trandafirescu G, Reid M, Kishore P, Hawkins M, Cohen HW, Barzilai N. Pilot study of resveratrol in older adults with impaired glucose tolerance. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 1307-12. PMID 22219517 DOI: 10.1093/Gerona/Glr235 |
0.655 |
|
| 2012 |
Ben-Shlomo S, Einstein FH, Zvibel I, Atias D, Shlomai A, Halpern Z, Barzilai N, Fishman S. Perinephric and epididymal fat affect hepatic metabolism in rats. Obesity (Silver Spring, Md.). 20: 151-6. PMID 21818154 DOI: 10.1038/Oby.2011.261 |
0.406 |
|
| 2012 |
Heo H, Karakash S, Huffman D, Delahaye F, Zhao Y, Barzilai N, Einstein F. 205: Sedentary behavior during pregnancy does not alter maternal fat distribution or insulin action American Journal of Obstetrics and Gynecology. 206: S103-S104. DOI: 10.1016/J.Ajog.2011.10.223 |
0.324 |
|
| 2012 |
Heo H, Slomko H, Karakash S, Delahaye F, Zhao Y, Huffman D, Barzilai N, Einstein F. 204: Impact of maternal diet on peripheral vs hepatic insulin resistance in young female offspring American Journal of Obstetrics and Gynecology. 206: S103. DOI: 10.1016/J.Ajog.2011.10.222 |
0.397 |
|
| 2011 |
Knight CM, Gutierrez-Juarez R, Lam TK, Arrieta-Cruz I, Huang L, Schwartz G, Barzilai N, Rossetti L. Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. Diabetes. 60: 2691-700. PMID 21896928 DOI: 10.2337/Db10-0987 |
0.373 |
|
| 2011 |
Tazearslan C, Huang J, Barzilai N, Suh Y. Impaired IGF1R signaling in cells expressing longevity-associated human IGF1R alleles. Aging Cell. 10: 551-4. PMID 21388493 DOI: 10.1111/J.1474-9726.2011.00697.X |
0.34 |
|
| 2011 |
Ben-Shlomo S, Zvibel I, Shnell M, Shlomai A, Chepurko E, Halpern Z, Barzilai N, Oren R, Fishman S. Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase. Journal of Hepatology. 54: 1214-23. PMID 21145820 DOI: 10.1016/J.Jhep.2010.09.032 |
0.337 |
|
| 2011 |
Heo H, Hou L, Karakash S, Zhao Y, Atzmon G, Barzilai N, Einstein F. 212: Metabolic alterations in visceral fat and liver contribute to persistent insulin resistance early postpartum American Journal of Obstetrics and Gynecology. 204: S93. DOI: 10.1016/J.Ajog.2010.10.228 |
0.388 |
|
| 2010 |
Barzilai N, Gabriely I, Atzmon G, Suh Y, Rothenberg D, Bergman A. Genetic studies reveal the role of the endocrine and metabolic systems in aging. The Journal of Clinical Endocrinology and Metabolism. 95: 4493-500. PMID 20926537 DOI: 10.1210/Jc.2010-0859 |
0.378 |
|
| 2010 |
Einstein FH, Huffman DM, Fishman S, Jerschow E, Heo HJ, Atzmon G, Schechter C, Barzilai N, Muzumdar RH. Aging per se increases the susceptibility to free fatty acid-induced insulin resistance. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 800-8. PMID 20504893 DOI: 10.1093/Gerona/Glq078 |
0.428 |
|
| 2010 |
Thompson RF, Atzmon G, Gheorghe C, Liang HQ, Lowes C, Greally JM, Barzilai N. Tissue-specific dysregulation of DNA methylation in aging. Aging Cell. 9: 506-18. PMID 20497131 DOI: 10.1111/J.1474-9726.2010.00577.X |
0.701 |
|
| 2010 |
Thompson RF, Fazzari MJ, Niu H, Barzilai N, Simmons RA, Greally JM. Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. The Journal of Biological Chemistry. 285: 15111-8. PMID 20194508 DOI: 10.1074/Jbc.M109.095133 |
0.714 |
|
| 2010 |
Einstein F, Thompson RF, Bhagat TD, Fazzari MJ, Verma A, Barzilai N, Greally JM. Cytosine methylation dysregulation in neonates following intrauterine growth restriction. Plos One. 5: e8887. PMID 20126273 DOI: 10.1371/Journal.Pone.0008887 |
0.676 |
|
| 2010 |
Atzmon G, Cho M, Cawthon RM, Budagov T, Katz M, Yang X, Siegel G, Bergman A, Huffman DM, Schechter CB, Wright WE, Shay JW, Barzilai N, Govindaraju DR, Suh Y. Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. Proceedings of the National Academy of Sciences of the United States of America. 107: 1710-7. PMID 19915151 DOI: 10.1073/Pnas.0906191106 |
0.351 |
|
| 2010 |
Barzilai N. Genetic and Epigenetic Contributions to Longevity Blood. 116. DOI: 10.1182/Blood.V116.21.Sci-1.Sci-1 |
0.374 |
|
| 2009 |
Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, et al. RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. Plos One. 4: e8210. PMID 20011587 DOI: 10.1371/Journal.Pone.0008210 |
0.356 |
|
| 2009 |
Muniyappa R, Chen H, Muzumdar RH, Einstein FH, Yan X, Yue LQ, Barzilai N, Quon MJ. Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats. American Journal of Physiology. Endocrinology and Metabolism. 297: E1023-9. PMID 19706785 DOI: 10.1152/Ajpendo.00397.2009 |
0.423 |
|
| 2009 |
Muzumdar RH, Huffman DM, Atzmon G, Buettner C, Cobb LJ, Fishman S, Budagov T, Cui L, Einstein FH, Poduval A, Hwang D, Barzilai N, Cohen P. Humanin: a novel central regulator of peripheral insulin action. Plos One. 4: e6334. PMID 19623253 DOI: 10.1371/Journal.Pone.0006334 |
0.427 |
|
| 2009 |
Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork NJ, Hsueh WC, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, et al. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity. Aging Cell. 8: 460-72. PMID 19489743 DOI: 10.1111/J.1474-9726.2009.00493.X |
0.381 |
|
| 2009 |
Huffman DM, Barzilai N. Role of visceral adipose tissue in aging. Biochimica Et Biophysica Acta. 1790: 1117-23. PMID 19364483 DOI: 10.1016/J.Bbagen.2009.01.008 |
0.404 |
|
| 2009 |
Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, LaCroix A, Tracy RP, Atzmon G, Lange EM, et al. Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Experimental Gerontology. 44: 350-5. PMID 19249341 DOI: 10.1016/J.Exger.2009.02.004 |
0.302 |
|
| 2009 |
Barzilai N, Bartke A. Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 187-91. PMID 19228789 DOI: 10.1093/Gerona/Gln061 |
0.314 |
|
| 2009 |
Barzilai N, Muzumdar R, Cohen P. Central regulation of peripheral insulin action Experimental Gerontology. 44: 123. DOI: 10.1016/J.Exger.2008.08.010 |
0.39 |
|
| 2009 |
Heo H, Donepudi R, Madankumar R, Huffman DM, Muzumdar R, Barzilai N, Einstein FH. 233: Hexosamine biosynthetic pathway: does it contribute to insulin resistance of pregnancy? American Journal of Obstetrics and Gynecology. 201: S97. DOI: 10.1016/J.Ajog.2009.10.248 |
0.358 |
|
| 2008 |
Einstein FH, Fishman S, Bauman J, Thompson RF, Huffman DM, Atzmon G, Barzilai N, Muzumdar RH. Enhanced activation of a "nutrient-sensing" pathway with age contributes to insulin resistance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3450-7. PMID 18566293 DOI: 10.1096/Fj.08-109041 |
0.701 |
|
| 2008 |
Atzmon G, Pollin TI, Crandall J, Tanner K, Schechter CB, Scherer PE, Rincon M, Siegel G, Katz M, Lipton RB, Shuldiner AR, Barzilai N. Adiponectin levels and genotype: a potential regulator of life span in humans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 447-53. PMID 18511746 DOI: 10.1093/Gerona/63.5.447 |
0.351 |
|
| 2008 |
Muzumdar R, Allison DB, Huffman DM, Ma X, Atzmon G, Einstein FH, Fishman S, Poduval AD, McVei T, Keith SW, Barzilai N. Visceral adipose tissue modulates mammalian longevity. Aging Cell. 7: 438-40. PMID 18363902 DOI: 10.1111/J.1474-9726.2008.00391.X |
0.364 |
|
| 2008 |
Suh Y, Atzmon G, Cho MO, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P. Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proceedings of the National Academy of Sciences of the United States of America. 105: 3438-42. PMID 18316725 DOI: 10.1073/Pnas.0705467105 |
0.396 |
|
| 2008 |
Einstein FH, Fishman S, Muzumdar RH, Yang XM, Atzmon G, Barzilai N. Accretion of visceral fat and hepatic insulin resistance in pregnant rats. American Journal of Physiology. Endocrinology and Metabolism. 294: E451-5. PMID 18073320 DOI: 10.1152/Ajpendo.00570.2007 |
0.398 |
|
| 2008 |
Barzilai N. Abstract ED04-02: The role of genes in protecting against age-related disease in cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Ed04-02 |
0.383 |
|
| 2008 |
Einstein F, Heo H, Cui L, Huffman DM, Muzumdar RH, Barzilai N. 717: Physiological insulin resistance of pregnancy leads to increased glucose uptake rat pups American Journal of Obstetrics and Gynecology. 199: S205. DOI: 10.1016/J.Ajog.2008.09.748 |
0.399 |
|
| 2008 |
Einstein F, Thompson RF, Heo H, Budagov T, Atzmon G, Goffman D, Barzilai N, Montagna C, Greally JM. 600: Abnormal intrauterine growth induces global epigenetic changes in human stem cells American Journal of Obstetrics and Gynecology. 199: S173. DOI: 10.1016/J.Ajog.2008.09.630 |
0.653 |
|
| 2008 |
Heo H, Cui L, Muzumdar RH, Huffman DM, Barzilai N, Einstein F. 539: Hepatic and peripheral insulin resistance of pregnancy are not reversed in early postpartum rats American Journal of Obstetrics and Gynecology. 199: S158. DOI: 10.1016/J.Ajog.2008.09.569 |
0.35 |
|
| 2007 |
Hwang JH, Stein DT, Barzilai N, Cui MH, Tonelli J, Kishore P, Hawkins M. Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies. American Journal of Physiology. Endocrinology and Metabolism. 293: E1663-9. PMID 17911339 DOI: 10.1152/Ajpendo.00590.2006 |
0.654 |
|
| 2007 |
Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N. Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging. Plos Computational Biology. 3: e170. PMID 17784782 DOI: 10.1371/Journal.Pcbi.0030170 |
0.366 |
|
| 2007 |
Martin GM, Bergman A, Barzilai N. Genetic determinants of human health span and life span: progress and new opportunities. Plos Genetics. 3: e125. PMID 17677003 DOI: 10.1371/Journal.Pgen.0030125 |
0.331 |
|
| 2007 |
Kim HS, Ali O, Shim M, Lee KW, Vuguin P, Muzumdar R, Barzilai N, Cohen P. Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo. Pediatric Research. 61: 159-64. PMID 17237715 DOI: 10.1203/Pdr.0B013E31802D8A30 |
0.425 |
|
| 2007 |
Fishman S, Muzumdar RH, Atzmon G, Ma X, Yang X, Einstein FH, Barzilai N. Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 53-60. PMID 17099068 DOI: 10.1096/Fj.06-6557Com |
0.405 |
|
| 2007 |
Einstein FH, Lo LW, Muzumdar RH, Fishman S, Atzmon G, Barzilai N. 43: Recurrent pregnancy is associated with visceral adiposity and insulin resistance, but not beta-cell dysfunction in a rodent model American Journal of Obstetrics and Gynecology. 197: S19. DOI: 10.1016/J.Ajog.2007.10.048 |
0.338 |
|
| 2006 |
Muzumdar RH, Ma X, Fishman S, Yang X, Atzmon G, Vuguin P, Einstein FH, Hwang D, Cohen P, Barzilai N. Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action. Diabetes. 55: 2788-96. PMID 17003344 DOI: 10.2337/Db06-0318 |
0.42 |
|
| 2006 |
Atzmon G, Rincon M, Schechter CB, Shuldiner AR, Lipton RB, Bergman A, Barzilai N. Lipoprotein genotype and conserved pathway for exceptional longevity in humans. Plos Biology. 4: e113. PMID 16602826 DOI: 10.1371/Journal.Pbio.0040113 |
0.393 |
|
| 2006 |
Muzumdar RH, Ma X, Yang X, Atzmon G, Barzilai N. Central resistance to the inhibitory effects of leptin on stimulated insulin secretion with aging. Neurobiology of Aging. 27: 1308-14. PMID 16122839 DOI: 10.1016/J.Neurobiolaging.2005.07.007 |
0.444 |
|
| 2006 |
Muzumdar R, Ma X, Yang X, Atzmon G, Cohen P, Barzilai N. OR13-4 DIRECT, CENTRAL, AND OPPOSING EFFECTS OF IGF-1 AND IGFBP-3 ON SYSTEMIC INSULIN ACTION Growth Hormone & Igf Research. 16: S25. DOI: 10.1016/S1096-6374(07)70260-5 |
0.364 |
|
| 2006 |
Einstein F, Fishman S, Muzumdar R, Yang XM, Atzmon G, Merkatz I, Barzilai N. Pregnancy alters adipose biology and its conribution to thrombosis, insulin action and inflammation American Journal of Obstetrics and Gynecology. 195: S152. DOI: 10.1016/J.Ajog.2006.10.537 |
0.369 |
|
| 2006 |
Einstein F, Fishman S, Muzumdar R, Yang XM, Atzmon G, Merkatz I, Barzilai N. Increased hepatic insulin resistance is detemined by visceral fat accretion and accumulation of hepatic triglycerides during pregnancy American Journal of Obstetrics and Gynecology. 195: S152. DOI: 10.1016/J.Ajog.2006.10.536 |
0.357 |
|
| 2005 |
Rincon M, Rudin E, Barzilai N. The insulin/IGF-1 signaling in mammals and its relevance to human longevity. Experimental Gerontology. 40: 873-7. PMID 16168602 DOI: 10.1016/J.Exger.2005.06.014 |
0.411 |
|
| 2005 |
Einstein FH, Atzmon G, Yang XM, Ma XH, Rincon M, Rudin E, Muzumdar R, Barzilai N. Differential responses of visceral and subcutaneous fat depots to nutrients. Diabetes. 54: 672-8. PMID 15734842 DOI: 10.2337/Diabetes.54.3.672 |
0.371 |
|
| 2005 |
Rudin E, Barzilai N. Inflammatory peptides derived from adipose tissue. Immunity & Ageing : I & A. 2: 1. PMID 15679897 DOI: 10.1186/1742-4933-2-1 |
0.34 |
|
| 2005 |
Arking DE, Atzmon G, Arking A, Barzilai N, Dietz HC. Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity. Circulation Research. 96: 412-8. PMID 15677572 DOI: 10.1161/01.Res.0000157171.04054.30 |
0.305 |
|
| 2005 |
Atzmon G, Rincon M, Rabizadeh P, Barzilai N. Biological evidence for inheritance of exceptional longevity. Mechanisms of Ageing and Development. 126: 341-5. PMID 15621216 DOI: 10.1016/J.Mad.2004.08.026 |
0.348 |
|
| 2005 |
Globerson A, Barzilai N. The voyage to healthy longevity: from experimental models to the ultimate goal. Mechanisms of Ageing and Development. 126: 225-9. PMID 15621200 DOI: 10.1016/J.Mad.2004.08.013 |
0.308 |
|
| 2005 |
Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, et al. The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. The Journal of Biological Chemistry. 280: 4617-26. PMID 15536073 DOI: 10.1074/Jbc.M411863200 |
0.656 |
|
| 2005 |
Rincon M, Muzumdar R, Atzmon G, Barzilai N. The paradox of the insulin/IGF-1 signaling pathway in longevity. Mechanisms of Ageing and Development. 125: 397-403. PMID 15272501 DOI: 10.1016/J.Mad.2004.03.006 |
0.419 |
|
| 2005 |
Einstein FH, Ma XH, Yang XM, Eric R, Muzumdar R, Merkatz IR, Barzilai N. Role of visceral fat in insulin resistance of pregnancy American Journal of Obstetrics and Gynecology. 193: S9. DOI: 10.1016/J.Ajog.2005.10.022 |
0.356 |
|
| 2004 |
Vuguin P, Raab E, Liu B, Barzilai N, Simmons R. Hepatic insulin resistance precedes the development of diabetes in a model of intrauterine growth retardation. Diabetes. 53: 2617-22. PMID 15448092 DOI: 10.2337/Diabetes.53.10.2617 |
0.451 |
|
| 2004 |
Barzilai N, Rossetti L, Lipton RB. Einstein's Institute for Aging Research: collaborative and programmatic approaches in the search for successful aging. Experimental Gerontology. 39: 151-7. PMID 15036407 DOI: 10.1016/J.Exger.2003.10.009 |
0.314 |
|
| 2004 |
Das M, Gabriely I, Barzilai N. Caloric restriction, body fat and ageing in experimental models. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 5: 13-9. PMID 14969503 DOI: 10.1111/J.1467-789X.2004.00115.X |
0.401 |
|
| 2004 |
Muzumdar R, Ma X, Atzmon G, Vuguin P, Yang X, Barzilai N. Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action. Diabetes. 53: 441-6. PMID 14747296 DOI: 10.2337/Diabetes.53.2.441 |
0.47 |
|
| 2004 |
Atzmon G, Schechter C, Greiner W, Davidson D, Rennert G, Barzilai N. Clinical phenotype of families with longevity. Journal of the American Geriatrics Society. 52: 274-7. PMID 14728640 DOI: 10.1111/J.1532-5415.2004.52068.X |
0.314 |
|
| 2003 |
Atwood CS, Barzilai N, Bowen RL, Brown-Borg HM, Jarrard DF, Fu VX, Heilbronn LK, Ingram DK, Ravussin E, Schwartz RS, Weindruch R. Pennington scientific symposium on mechanisms and retardation of aging. Experimental Gerontology. 38: 1217-26. PMID 14580876 DOI: 10.1016/J.Exger.2003.08.005 |
0.353 |
|
| 2003 |
Barzilai N, Atzmon G, Schechter C, Schaefer EJ, Cupples AL, Lipton R, Cheng S, Shuldiner AR. Unique lipoprotein phenotype and genotype associated with exceptional longevity. Jama. 290: 2030-40. PMID 14559957 DOI: 10.1016/J.Accreview.2003.12.029 |
0.328 |
|
| 2003 |
Gabriely I, Barzilai N. Surgical removal of visceral adipose tissue: effects on insulin action. Current Diabetes Reports. 3: 201-6. PMID 12762966 DOI: 10.1007/S11892-003-0064-3 |
0.436 |
|
| 2003 |
Muzumdar R, Ma X, Yang X, Atzmon G, Bernstein J, Karkanias G, Barzilai N. Physiologic effect of leptin on insulin secretion is mediated mainly through central mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1130-2. PMID 12709405 DOI: 10.1096/Fj.02-0991Fje |
0.424 |
|
| 2003 |
Ma X, Muzumdar R, Gabriely I, Atzmon G, Barzilai N. Does the brain lead the metabolic decline in aging? Clinical Neuroscience Research. 2: 339-344. DOI: 10.1016/S1566-2772(03)00011-2 |
0.433 |
|
| 2002 |
Gabriely I, Ma XH, Yang XM, Atzmon G, Rajala MW, Berg AH, Scherer P, Rossetti L, Barzilai N. Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? Diabetes. 51: 2951-8. PMID 12351432 DOI: 10.2337/Diabetes.51.10.2951 |
0.467 |
|
| 2002 |
Rajala MW, Lin Y, Ranalletta M, Yang XM, Qian H, Gingerich R, Barzilai N, Scherer PE. Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue. Molecular Endocrinology (Baltimore, Md.). 16: 1920-30. PMID 12145345 DOI: 10.1210/Me.2002-0048 |
0.339 |
|
| 2002 |
Ma XH, Muzumdar R, Yang XM, Gabriely I, Berger R, Barzilai N. Aging is associated with resistance to effects of leptin on fat distribution and insulin action. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 57: B225-31. PMID 12023258 DOI: 10.1093/Gerona/57.6.B225 |
0.446 |
|
| 2002 |
Gabriely I, Ma XH, Yang XM, Rossetti L, Barzilai N. Leptin resistance during aging is independent of fat mass. Diabetes. 51: 1016-21. PMID 11916920 DOI: 10.2337/Diabetes.51.4.1016 |
0.41 |
|
| 2002 |
Gabriely I, Yang XM, Cases JA, Ma XH, Rossetti L, Barzilai N. Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway. Atherosclerosis. 160: 115-22. PMID 11755928 DOI: 10.1016/S0021-9150(01)00574-3 |
0.387 |
|
| 2001 |
Wang J, Obici S, Morgan K, Barzilai N, Feng Z, Rossetti L. Overfeeding rapidly induces leptin and insulin resistance. Diabetes. 50: 2786-91. PMID 11723062 DOI: 10.2337/Diabetes.50.12.2786 |
0.427 |
|
| 2001 |
Lin Y, Rajala MW, Berger JP, Moller DE, Barzilai N, Scherer PE. Hyperglycemia-induced production of acute phase reactants in adipose tissue. The Journal of Biological Chemistry. 276: 42077-83. PMID 11546817 DOI: 10.1074/Jbc.M107101200 |
0.314 |
|
| 2001 |
Gabriely I, Barzilai N. The role of fat cell derived peptides in age-related metabolic alterations. Mechanisms of Ageing and Development. 122: 1565-76. PMID 11511397 DOI: 10.1016/S0047-6374(01)00287-1 |
0.353 |
|
| 2001 |
Gabriely I, Yang XM, Cases JA, Ma XH, Rossetti L, Barzilai N. Hyperglycemia modulates angiotensinogen gene expression. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 281: R795-802. PMID 11506994 DOI: 10.1152/Ajpregu.2001.281.3.R795 |
0.414 |
|
| 2001 |
Cases JA, Gabriely I, Ma XH, Yang XM, Michaeli T, Fleischer N, Rossetti L, Barzilai N. Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes. 50: 348-52. PMID 11272146 DOI: 10.2337/Diabetes.50.2.348 |
0.43 |
|
| 2001 |
Vuguin P, Ma X, Yang X, Surana M, Liu B, Barzilai N. Food deprivation limits insulin secretory capacity in postpubertal rats. Pediatric Research. 49: 468-73. PMID 11264428 DOI: 10.1203/00006450-200104000-00006 |
0.419 |
|
| 2001 |
Barzilai N, Gabriely I. The role of fat depletion in the biological benefits of caloric restriction. The Journal of Nutrition. 131: 903S-906S. PMID 11238783 DOI: 10.1093/Jn/131.3.903S |
0.339 |
|
| 2001 |
Barzilai N, Shuldiner AR. Searching for human longevity genes: the future history of gerontology in the post-genomic era. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: M83-7. PMID 11213281 DOI: 10.1093/Gerona/56.2.M83 |
0.31 |
|
| 2001 |
Cases JA, Barzilai N. The regulation of body fat distribution and the modulation of insulin action. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. S63-6. PMID 11126245 DOI: 10.1038/Sj.Ijo.0801508 |
0.423 |
|
| 2000 |
Barzilai N, Gupta G. Interaction between aging and syndrome X: new insights on the pathophysiology of fat distribution. Annals of the New York Academy of Sciences. 892: 58-72. PMID 10842652 DOI: 10.1111/J.1749-6632.1999.Tb07785.X |
0.466 |
|
| 2000 |
Gupta G, Cases JA, She L, Ma XH, Yang XM, Hu M, Wu J, Rossetti L, Barzilai N. Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation. American Journal of Physiology. Endocrinology and Metabolism. 278: E985-91. PMID 10826999 DOI: 10.1152/Ajpendo.2000.278.6.E985 |
0.421 |
|
| 2000 |
Gupta G, She L, Ma XH, Yang XM, Hu M, Cases JA, Vuguin P, Rossetti L, Barzilai N. Aging does not contribute to the decline in insulin action on storage of muscle glycogen in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R111-7. PMID 10644628 DOI: 10.1152/Ajpregu.2000.278.1.R111 |
0.416 |
|
| 1999 |
Hawkins M, Hu M, Yu J, Eder H, Vuguin P, She L, Barzilai N, Leiser M, Backer JM, Rossetti L. Discordant effects of glucosamine on insulin-stimulated glucose metabolism and phosphatidylinositol 3-kinase activity Journal of Biological Chemistry. 274: 31312-31319. PMID 10531330 DOI: 10.1074/Jbc.274.44.31312 |
0.677 |
|
| 1999 |
Barzilai N, She L, Liu L, Wang J, Hu M, Vuguin P, Rossetti L. Decreased visceral adiposity accounts for leptin effect on hepatic but not peripheral insulin action. The American Journal of Physiology. 277: E291-8. PMID 10444425 DOI: 10.1152/Ajpendo.1999.277.2.E291 |
0.406 |
|
| 1999 |
Wang J, Liu R, Liu L, Chowdhury R, Barzilai N, Tan J, Rossetti L. The effect of leptin on Lep expression is tissue-specific and nutritionally regulated. Nature Medicine. 5: 895-9. PMID 10426312 DOI: 10.1038/11335 |
0.316 |
|
| 1999 |
Barzilai N, Gupta G. Revisiting the role of fat mass in the life extension induced by caloric restriction. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 54: B89-96; discussion B. PMID 10191831 DOI: 10.1093/Gerona/54.3.B89 |
0.388 |
|
| 1999 |
Barzilai N, She L, Liu BQ, Vuguin P, Cohen P, Wang J, Rossetti L. Surgical removal of visceral fat reverses hepatic insulin resistance. Diabetes. 48: 94-8. PMID 9892227 DOI: 10.2337/Diabetes.48.1.94 |
0.448 |
|
| 1999 |
Vuguin P, She L, Surana N, Liu B, Saenger P, Barzilai N. Marked Increase in the Ability of the β-Cells to Secrete Insulin in Response to Glucose and FFA Occurs Post-Puberty Pediatric Research. 45: 99A-99A. DOI: 10.1203/00006450-199904020-00593 |
0.391 |
|
| 1999 |
Barzilai N. Author's Repsonse to Commentary on "Revisiting the Role of Fat Mass in the Life Extension Induced by Caloric Restriction" The Journals of Gerontology Series a: Biological Sciences and Medical Sciences. 54: B98-B98. DOI: 10.1093/Gerona/54.3.B98 |
0.376 |
|
| 1998 |
Liu L, Karkanias GB, Morales JC, Hawkins M, Barzilai N, Wang J, Rossetti L. Intracerebroventricular leptin regulates hepatic but not peripheral glucose fluxes. The Journal of Biological Chemistry. 273: 31160-7. PMID 9813020 DOI: 10.1074/Jbc.273.47.31160 |
0.67 |
|
| 1998 |
Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature. 393: 684-8. PMID 9641678 DOI: 10.1038/31474 |
0.629 |
|
| 1998 |
Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. The Journal of Clinical Investigation. 101: 1353-61. PMID 9525977 DOI: 10.1172/Jci485 |
0.687 |
|
| 1998 |
Barzilai N, Banerjee S, Hawkins M, Chang CJ, Chen W, Rossetti L. The effect of age-dependent increase in fat mass on peripheral insulin action is saturable. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B141-6. PMID 9520910 DOI: 10.1093/Gerona/53A.2.B141 |
0.697 |
|
| 1998 |
Massillon D, Chen W, Barzilai N, Prus-Wertheimer D, Hawkins M, Liu R, Taub R, Rossetti L. Carbon flux via the pentose phosphate pathway regulates the hepatic expression of the glucose-6-phosphatase and phosphoenolpyruvate carboxykinase genes in conscious rats. The Journal of Biological Chemistry. 273: 228-34. PMID 9417069 DOI: 10.1074/Jbc.273.1.228 |
0.618 |
|
| 1998 |
Barzilai N, Wang J, Massilon D, Vuguin P, Hawkins M, Rossetti L. Leptin selectively decreases visceral adiposity and enhances insulin action. The Journal of Clinical Investigation. 100: 3105-10. PMID 9399957 DOI: 10.1172/Jci119865 |
0.686 |
|
| 1997 |
Banerjee S, Saenger P, Hu M, Chen W, Barzilai N. Fat accretion and the regulation of insulin-mediated glycogen synthesis after puberty in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 273: R1534-R1539. PMID 29586743 DOI: 10.1152/Ajpregu.1997.273.4.R1534 |
0.413 |
|
| 1997 |
Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S. Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. American Journal of Physiology. Endocrinology and Metabolism. 273: E743-E750. PMID 29585232 DOI: 10.1152/Ajpendo.1997.273.4.E743 |
0.657 |
|
| 1997 |
Rossetti L, Massillon D, Barzilai N, Vuguin P, Chen W, Hawkins M, Wu J, Wang J. Short term effects of leptin on hepatic gluconeogenesis and in vivo insulin action. The Journal of Biological Chemistry. 272: 27758-63. PMID 9346919 DOI: 10.1074/Jbc.272.44.27758 |
0.685 |
|
| 1997 |
Rossetti L, Stenbit AE, Chen W, Hu M, Barzilai N, Katz EB, Charron MJ. Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene Journal of Clinical Investigation. 100: 1831-1839. PMID 9312184 DOI: 10.1172/Jci119711 |
0.42 |
|
| 1997 |
Hawkins M, Barzilai N, Liu R, Hu M, Chen W, Rossetti L. Role of the glucosamine pathway in fat-induced insulin resistance. The Journal of Clinical Investigation. 99: 2173-82. PMID 9151789 DOI: 10.1172/Jci119390 |
0.671 |
|
| 1997 |
Raghavan S, Saenger P, Hu M, Barzilai N. Intracellular pathways of insulin-mediated glucose uptake before and after puberty in conscious rats. Pediatric Research. 41: 340-5. PMID 9078532 DOI: 10.1203/00006450-199703000-00006 |
0.439 |
|
| 1997 |
Hawkins M, Angelov I, Liu R, Barzilai N, Rossetti L. The tissue concentration of UDP-N-acetylglucosamine modulates the stimulatory effect of insulin on skeletal muscle glucose uptake. The Journal of Biological Chemistry. 272: 4889-95. PMID 9030547 DOI: 10.1074/Jbc.272.8.4889 |
0.666 |
|
| 1997 |
Massillon D, Barzilai N, Hawkins M, Prus-Wertheimer D, Rossetti L. Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion. Diabetes. 46: 153-7. PMID 8971097 DOI: 10.2337/Diab.46.1.153 |
0.669 |
|
| 1997 |
Banerjee S, Saenger P, Chen W, Rossetti L, Barzilai N. Prevention of Fat Accretion through Puberty restores Insulin Action on Glycogen Synthesis to Prepubertal Levels in Conscious Rats. † 373 Pediatric Research. 41: 65-65. DOI: 10.1203/00006450-199704001-00393 |
0.386 |
|
| 1996 |
Hawkins M, Barzilai N, Chen W, Angelov I, Hu M, Cohen P, Rossetti L. Increased hexosamine availability similarly impairs the action of insulin and IGF-1 on glucose disposal. Diabetes. 45: 1734-43. PMID 8922359 DOI: 10.2337/Diab.45.12.1734 |
0.673 |
|
| 1996 |
Barzilai N, Hawkins M, Angelov I, Hu M, Rossetti L. Glucosamine-induced inhibition of liver glucokinase impairs the ability of hyperglycemia to suppress endogenous glucose production. Diabetes. 45: 1329-35. PMID 8826967 DOI: 10.2337/Diab.45.10.1329 |
0.658 |
|
| 1996 |
Barzilai N, Rossetti L. Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats. The American Journal of Physiology. 270: E930-6. PMID 8764175 DOI: 10.1152/Ajpendo.1996.270.6.E930 |
0.463 |
|
| 1996 |
Barzilai N, Groop PH, Groop L, DeFronzo RA. A novel mechanism of glipizide sulfonylurea action: decreased metabolic clearance rate of insulin. Acta Diabetologica. 32: 273-8. PMID 8750768 DOI: 10.1007/Bf00576262 |
0.422 |
|
| 1996 |
Massillon D, Barzilai N, Chen W, Hu M, Rossetti L. Glucose regulates in vivo glucose-6-phosphatase gene expression in the liver of diabetic rats. The Journal of Biological Chemistry. 271: 9871-4. PMID 8626617 DOI: 10.1074/Jbc.271.17.9871 |
0.409 |
|
| 1996 |
Massillon D, Chen W, Hawkins M, Liu R, Barzilai N, Rossetti L. Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice. The American Journal of Physiology. 269: E1037-43. PMID 8572194 DOI: 10.1152/Ajpendo.1995.269.6.E1037 |
0.64 |
|
| 1996 |
Rossetti L, Barzilai N, Chen W, Harris T, Yang D, Rogler CE. Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice. The Journal of Biological Chemistry. 271: 203-8. PMID 8550560 DOI: 10.1074/Jbc.271.1.203 |
0.418 |
|
| 1995 |
Bali D, Svetlanov A, Lee HW, Fusco-DeMane D, Leiser M, Li B, Barzilai N, Surana M, Hou H, Fleischer N, DePinho R, Rossetti L, Efrat S. Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene Journal of Biological Chemistry. 270: 21464-21467. PMID 7665557 DOI: 10.1074/Jbc.270.37.21464 |
0.424 |
|
| 1995 |
Rossetti L, Hawkins M, Chen W, Gindi J, Barzilai N. In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats. The Journal of Clinical Investigation. 96: 132-40. PMID 7615783 DOI: 10.1172/Jci118013 |
0.671 |
|
| 1995 |
Barzilai N, Massillon D, Rossetti L. Effects of fasting on hepatic and peripheral glucose metabolism in conscious rats with near-total fat depletion. The Biochemical Journal. 819-26. PMID 7575414 DOI: 10.1042/Bj3100819 |
0.417 |
|
| 1995 |
Barzilai N, Rossetti L. Relationship between changes in body composition and insulin responsiveness in models of the aging rat. The American Journal of Physiology. 269: E591-7. PMID 7573438 DOI: 10.1152/Ajpendo.1995.269.3.E591 |
0.456 |
|
| 1993 |
Rossetti L, Giaccari A, Barzilai N, Howard K, Sebel G, Hu M. Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes. The Journal of Clinical Investigation. 92: 1126-34. PMID 8397219 DOI: 10.1172/Jci116681 |
0.388 |
|
| 1992 |
DeFronzo RA, Barzilai N, Simonson DC. Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects. The Journal of Clinical Endocrinology and Metabolism. 73: 1294-301. PMID 1955512 DOI: 10.1210/jcem-73-6-1294 |
0.302 |
|
| 1992 |
Barzilai N, Cohen P, Karnieli E, Enat R, Epstein O, Owen J, McIntyre N. In vivo insulin action in hepatocellular and cholestatic liver cirrhosis. Journal of Endocrinological Investigation. 14: 727-35. PMID 1761807 DOI: 10.1007/BF03347904 |
0.323 |
|
| 1991 |
Groop LC, Barzilai N, Ratheiser K, Luzi L, Wåhlin-Boll E, Melander A, DeFronzo RA. Dose-dependent effects of glyburide on insulin secretion and glucose uptake in humans. Diabetes Care. 14: 724-7. PMID 1954808 DOI: 10.2337/Diacare.14.8.724 |
0.412 |
|
| 1991 |
Barzilai N, Cohen P, Bar-Illan R, McIntyre N, Karnieli E. Case report: increased insulin sensitivity in tumor hypoglycemia in a diabetic patient: glucose metabolism in tumor hypoglycemia. The American Journal of the Medical Sciences. 302: 229-34. PMID 1656753 DOI: 10.1097/00000441-199110000-00007 |
0.314 |
|
| 1990 |
Cohen P, Harel C, Bergman R, Daoud D, Pam Z, Barzilai N, Armoni M, Karnieli E. Insulin resistance and acanthosis nigricans: evidence for a postbinding defect in vivo. Metabolism: Clinical and Experimental. 39: 1006-11. PMID 2215248 DOI: 10.1016/0026-0495(90)90158-9 |
0.316 |
|
| 1989 |
Barzilai N, Stessman J, Cohen P, Morali G, Barzilai D, Karnieli E. Glucoregulatory hormone influence on hepatic glucose production in the elderly Age. 12: 13-17. DOI: 10.1007/Bf02432513 |
0.342 |
|
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