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Goutam Chowdhury, PhD - Publications

Affiliations: 
Chemistry Shiv Nadar University 
Website:
http://snu.edu.in/naturalsciences/Chowdhury_G_Profile.aspx
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Babu G, Das A, Chakrabarty A, Chowdhury G, Goswami M. Criegee Intermediate-Mediated Oxidation of Dimethyl Disulfide: Effect of Formic Acid and Its Atmospheric Relevance. The Journal of Physical Chemistry. A. 127: 8415-8426. PMID 37782474 DOI: 10.1021/acs.jpca.3c04730  0.705
2022 Chakraborty S, Mallick D, Goswami M, Guengerich FP, Chakrabarty A, Chowdhury G. The Natural Products Withaferin A and Withanone from the Medicinal Herb Are Covalent Inhibitors of the SARS-CoV-2 Main Protease. Journal of Natural Products. PMID 36098617 DOI: 10.1021/acs.jnatprod.2c00521  0.689
2021 Chakrabarty A, Surendran S, Bhola NE, Mishra VS, Wani TH, Baghel KS, Arteaga CL, Garg R, Chowdhury G. Corrigendum to: The H1047R PIK3CA oncogene induces a senescence-like state, pleiotropy and acute HSP90 dependency in HER2+ mammary epithelial cells. Carcinogenesis. PMID 34363390 DOI: 10.1093/carcin/bgab065  0.646
2021 Siddiqui S, Ahmed N, Goswami M, Chakrabarty A, Chowdhury G. DNA damage by Withanone as a potential cause of liver toxicity observed for herbal products of (Ashwagandha). Current Research in Toxicology. 2: 72-81. PMID 34345852 DOI: 10.1016/j.crtox.2021.02.002  0.714
2021 Chakrabarty A, Chakraborty S, Bhattacharya R, Chowdhury G. Senescence-Induced Chemoresistance in Triple Negative Breast Cancer and Evolution-Based Treatment Strategies. Frontiers in Oncology. 11: 674354. PMID 34249714 DOI: 10.3389/fonc.2021.674354  0.677
2021 Wani TH, Chowdhury G, Chakrabarty A. Generation of reactive oxygen species is the primary mode of action and cause of survivin suppression by sepantronium bromide (YM155). Rsc Medicinal Chemistry. 12: 566-578. PMID 34046628 DOI: 10.1039/d0md00383b  0.7
2020 Ahmed N, Chakrabarty A, Guengerich FP, Chowdhury G. Protective Role of Glutathione Against Peroxynitrite-Mediated DNA Damage During Acute Inflammation. Chemical Research in Toxicology. PMID 32894672 DOI: 10.1021/Acs.Chemrestox.0C00299  0.766
2019 Chakrabarty A, Surendran S, Bhola NE, Mishra VS, Wani TH, Baghel KS, Arteaga CL, Garg R, Chowdhury G. The H1047R PIK3CA oncogene induces a senescence-like state, pleiotropy and acute HSP90 dependency in HER2+ mammary epithelial cells. Carcinogenesis. PMID 31219154 DOI: 10.1093/Carcin/Bgz118  0.681
2018 Wani TH, Surendran S, Mishra VS, Chaturvedi J, Chowdhury G, Chakrabarty A. Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells. Oncotarget. 9: 33589-33600. PMID 30323901 DOI: 10.18632/Oncotarget.26096  0.742
2018 Wani TH, Surendran S, Jana A, Chakrabarty A, Chowdhury G. The Quinone Based Antitumor Agent Sepantronium Bromide (YM155) Causes Oxygen Independent Redox Activated Oxidative DNA Damage. Chemical Research in Toxicology. PMID 29897742 DOI: 10.1021/Acs.Chemrestox.8B00094  0.803
2017 Wani TH, Chakrabarty A, Shibata N, Yamazaki H, Guengerich FP, Chowdhury G. The Dihydroxy Metabolite of the Teratogen Thalidomide Causes Oxidative DNA Damage. Chemical Research in Toxicology. PMID 28745489 DOI: 10.1021/Acs.Chemrestox.7B00127  0.793
2015 Chowdhury G, Guengerich FP. Characterization of thioether-linked protein adducts of DNA using a raney-ni-mediated desulfurization method and liquid chromatography-electrospray-tandem mass spectrometry. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. 60: 10.15.1-10.15.14. PMID 25754888 DOI: 10.1002/0471142700.Nc1015S60  0.491
2014 Chowdhury G, Shibata N, Yamazaki H, Guengerich FP. Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide. Chemical Research in Toxicology. 27: 147-56. PMID 24350712 DOI: 10.1021/Tx4004215  0.481
2013 Chowdhury G, Cho SH, Pegg AE, Guengerich FP. Detection and characterization of 1,2-dibromoethane-derived DNA crosslinks formed with O(6) -alkylguanine-DNA alkyltransferase. Angewandte Chemie (International Ed. in English). 52: 12879-82. PMID 24130045 DOI: 10.1002/Anie.201307580  0.563
2013 Bajpai P, Sangar MC, Singh S, Tang W, Bansal S, Chowdhury G, Cheng Q, Fang JK, Martin MV, Guengerich FP, Avadhani NG. Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease. The Journal of Biological Chemistry. 288: 4436-51. PMID 23258538 DOI: 10.1074/Jbc.M112.402123  0.424
2012 Chowdhury G, Calcutt MW, Nagy LD, Guengerich FP. Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1. Biochemistry. 51: 9995-10007. PMID 23186213 DOI: 10.1021/Bi301092C  0.463
2012 Yamazaki H, Suemizu H, Shimizu M, Igaya S, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice. Chemical Research in Toxicology. 25: 274-6. PMID 22268628 DOI: 10.1021/Tx300009J  0.403
2012 Chowdhury G, Sarkar U, Pullen S, Wilson WR, Rajapakse A, Fuchs-Knotts T, Gates KS. DNA strand cleavage by the phenazine di-N-oxide natural product myxin under both aerobic and anaerobic conditions. Chemical Research in Toxicology. 25: 197-206. PMID 22084973 DOI: 10.1021/Tx2004213  0.806
2011 Chowdhury G, Guengerich FP. Liquid chromatography-mass spectrometry analysis of DNA polymerase reaction products. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 7.16.1-11. PMID 22147421 DOI: 10.1002/0471142700.Nc0716S47  0.516
2011 Yamazaki H, Suemizu H, Igaya S, Shimizu M, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice. Chemical Research in Toxicology. 24: 287-9. PMID 21299192 DOI: 10.1021/Tx200005G  0.4
2011 Guengerich FP, Sohl CD, Chowdhury G. Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms. Archives of Biochemistry and Biophysics. 507: 126-34. PMID 20804723 DOI: 10.1016/J.Abb.2010.08.017  0.71
2010 Chowdhury G, Murayama N, Okada Y, Uno Y, Shimizu M, Shibata N, Guengerich FP, Yamazaki H. Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate. Chemical Research in Toxicology. 23: 1018-24. PMID 20443640 DOI: 10.1021/Tx900367P  0.406
2010 Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Chemical Research in Toxicology. 23: 1076-88. PMID 20377178 DOI: 10.1021/Tx100053N  0.548
2010 Chowdhury G, Calcutt MW, Guengerich FP. Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps. The Journal of Biological Chemistry. 285: 8031-44. PMID 20061389 DOI: 10.1074/Jbc.M109.088039  0.503
2009 Nguyen LP, Hsu EL, Chowdhury G, Dostalek M, Guengerich FP, Bradfield CA. D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan. Chemical Research in Toxicology. 22: 1897-904. PMID 19860415 DOI: 10.1021/Tx900043S  0.454
2009 Chowdhury G, Dostalek M, Hsu EL, Nguyen LP, Stec DF, Bradfield CA, Guengerich FP. Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid. Chemical Research in Toxicology. 22: 1905-12. PMID 19860413 DOI: 10.1021/Tx9000418  0.462
2009 Chowdhury G, Guengerich FP. Tandem mass spectrometry-based detection of c4'-oxidized abasic sites at specific positions in DNA fragments. Chemical Research in Toxicology. 22: 1310-9. PMID 19496605 DOI: 10.1021/Tx900115Z  0.543
2008 Fang Q, Noronha AM, Murphy SP, Wilds CJ, Tubbs JL, Tainer JA, Chowdhury G, Guengerich FP, Pegg AE. Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase. Biochemistry. 47: 10892-903. PMID 18803403 DOI: 10.1021/Bi8008664  0.555
2008 Chowdhury G, Guengerich FP. Direct detection and mapping of sites of base modification in DNA fragments by tandem mass spectrometry Angewandte Chemie - International Edition. 47: 381-384. PMID 18022988 DOI: 10.1002/Anie.200703942  0.481
2007 Chowdhury G, Junnotula V, Daniels JS, Greenberg MM, Gates KS. DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2). Journal of the American Chemical Society. 129: 12870-7. PMID 17900117 DOI: 10.1021/Ja074432M  0.814
2007 LaButti JN, Chowdhury G, Reilly TJ, Gates KS. Redox regulation of protein tyrosine phosphatase 1B by peroxymonophosphate (=O3POOH). Journal of the American Chemical Society. 129: 5320-1. PMID 17411049 DOI: 10.1021/Ja070194J  0.739
2007 Dutta S, Chowdhury G, Gates KS. Interstrand cross-links generated by abasic sites in duplex DNA. Journal of the American Chemical Society. 129: 1852-3. PMID 17253689 DOI: 10.1021/Ja067294U  0.64
2006 Stover JS, Chowdhury G, Zang H, Guengerich FP, Rizzo CJ. Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases. Chemical Research in Toxicology. 19: 1506-17. PMID 17112239 DOI: 10.1021/Tx0601455  0.716
2006 Choi JY, Chowdhury G, Zang H, Angel KC, Vu CC, Peterson LA, Guengerich FP. Translesion synthesis across O6-alkylguanine DNA adducts by recombinant human DNA polymerases. The Journal of Biological Chemistry. 281: 38244-56. PMID 17050527 DOI: 10.1074/Jbc.M608369200  0.689
2006 Choi JY, Stover JS, Angel KC, Chowdhury G, Rizzo CJ, Guengerich FP. Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. The Journal of Biological Chemistry. 281: 25297-306. PMID 16835218 DOI: 10.1074/Jbc.M605699200  0.496
2006 Zang H, Chowdhury G, Angel KC, Harris TM, Guengerich FP. Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4. Chemical Research in Toxicology. 19: 859-67. PMID 16780366 DOI: 10.1021/Tx060056S  0.739
2004 Chowdhury G, Kotandeniya D, Daniels JS, Barnes CL, Gates KS. Enzyme-activated, hypoxia-selective DNA damage by 3-amino-2-quinoxalinecarbonitrile 1,4-di-N-oxide. Chemical Research in Toxicology. 17: 1399-405. PMID 15540937 DOI: 10.1021/Tx049836W  0.824
2003 Birincioglu M, Jaruga P, Chowdhury G, Rodriguez H, Dizdaroglu M, Gates KS. DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine). Journal of the American Chemical Society. 125: 11607-15. PMID 13129365 DOI: 10.1021/Ja0352146  0.691
2003 Chatterji T, Kizil M, Keerthi K, Chowdhury G, Pospísil T, Gates KS. Small molecules that mimic the thiol-triggered alkylating properties seen in the natural product leinamycin. Journal of the American Chemical Society. 125: 4996-7. PMID 12708847 DOI: 10.1021/Ja029169Y  0.753
2002 Poole JS, Hadad CM, Platz MS, Fredin ZP, Pickard L, Guerrero EL, Kessler M, Chowdhury G, Kotandeniya D, Gates KS. Photochemical electron transfer reactions of tirapazamine. Photochemistry and Photobiology. 75: 339-45. PMID 12003122 DOI: 10.1562/0031-8655(2002)075<0339:Petrot>2.0.Co;2  0.742
2001 Ganley B, Chowdhury G, Bhansali J, Daniels JS, Gates KS. Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide. Bioorganic & Medicinal Chemistry. 9: 2395-401. PMID 11553481 DOI: 10.1016/S0968-0896(01)00163-8  0.766
2001 Fuchs T, Chowdhury G, Barnes CL, Gates KS. 3-amino-1,2,4-benzotriazine 4-oxide: characterization of a new metabolite arising from bioreductive processing of the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine). The Journal of Organic Chemistry. 66: 107-14. PMID 11429885 DOI: 10.1021/Jo001232J  0.787
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