Anne Chomyn - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
Mitochondrial biogenesis

49/55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hashimoto M, Bacman SR, Peralta S, Falk MJ, Chomyn A, Chan DC, Williams SL, Moraes CT. MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26159306 DOI: 10.1038/Mt.2015.126  0.48
2012 Chen A, Raule N, Chomyn A, Attardi G. Decreased reactive oxygen species production in cells with mitochondrial haplogroups associated with longevity. Plos One. 7: e46473. PMID 23144696 DOI: 10.1371/Journal.Pone.0046473  0.48
2010 Chen H, Vermulst M, Wang YE, Chomyn A, Prolla TA, McCaffery JM, Chan DC. Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell. 141: 280-9. PMID 20403324 DOI: 10.1016/J.Cell.2010.02.026  0.48
2007 Iwata N, Zhang J, Atzmon G, Leanza S, Cho J, Chomyn A, Burk RD, Barzilai N, Attardi G. Aging-related occurrence in Ashkenazi Jews of leukocyte heteroplasmic mtDNA mutation adjacent to replication origin frequently remodeled in Italian centenarians. Mitochondrion. 7: 267-72. PMID 17452024 DOI: 10.1016/J.Mito.2007.03.001  0.48
2007 Hájek P, Chomyn A, Attardi G. Identification of a novel mitochondrial complex containing mitofusin 2 and stomatin-like protein 2. The Journal of Biological Chemistry. 282: 5670-81. PMID 17121834 DOI: 10.1074/Jbc.M608168200  0.48
2006 Duvezin-Caubet S, Jagasia R, Wagener J, Hofmann S, Trifunovic A, Hansson A, Chomyn A, Bauer MF, Attardi G, Larsson NG, Neupert W, Reichert AS. Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology. The Journal of Biological Chemistry. 281: 37972-9. PMID 17003040 DOI: 10.1074/Jbc.M606059200  0.48
2005 Chen H, Chomyn A, Chan DC. Disruption of fusion results in mitochondrial heterogeneity and dysfunction. The Journal of Biological Chemistry. 280: 26185-92. PMID 15899901 DOI: 10.1074/Jbc.M503062200  0.48
2004 Bai Y, Hu P, Park JS, Deng JH, Song X, Chomyn A, Yagi T, Attardi G. Genetic and functional analysis of mitochondrial DNA-encoded complex I genes. Annals of the New York Academy of Sciences. 1011: 272-83. PMID 15126303 DOI: 10.1196/Annals.1293.026  0.48
2003 Chomyn A, Attardi G. MtDNA mutations in aging and apoptosis. Biochemical and Biophysical Research Communications. 304: 519-29. PMID 12729587 DOI: 10.1016/S0006-291X(03)00625-9  0.48
2003 Duan S, Hajek P, Lin C, Shin SK, Attardi G, Chomyn A. Mitochondrial outer membrane permeability change and hypersensitivity to digitonin early in staurosporine-induced apoptosis. The Journal of Biological Chemistry. 278: 1346-53. PMID 12403774 DOI: 10.1074/Jbc.M209269200  0.48
2001 Chomyn A. Mitochondrial genetic control of assembly and function of complex I in mammalian cells. Journal of Bioenergetics and Biomembranes. 33: 251-7. PMID 11695835 DOI: 10.1023/A:1010791204961  0.48
2001 Bai Y, Hájek P, Chomyn A, Chan E, Seo BB, Matsuno-Yagi A, Yagi T, Attardi G. Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene. The Journal of Biological Chemistry. 276: 38808-13. PMID 11479321 DOI: 10.1074/Jbc.M106363200  0.48
2000 Chomyn A, Enriquez JA, Micol V, Fernandez-Silva P, Attardi G. The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode syndrome-associated human mitochondrial tRNALeu(UUR) mutation causes aminoacylation deficiency and concomitant reduced association of mRNA with ribosomes. The Journal of Biological Chemistry. 275: 19198-209. PMID 10858457 DOI: 10.1074/Jbc.M908734199  0.48
1999 Helm M, Florentz C, Chomyn A, Attardi G. Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR). Nucleic Acids Research. 27: 756-63. PMID 9889270 DOI: 10.1093/Nar/27.3.756  0.48
1998 Chomyn A. The myoclonic epilepsy and ragged-red fiber mutation provides new insights into human mitochondrial function and genetics. American Journal of Human Genetics. 62: 745-51. PMID 9529371 DOI: 10.1086/301813  0.48
1997 Zhou L, Chomyn A, Attardi G, Miller CA. Myoclonic epilepsy and ragged red fibers (MERRF) syndrome: selective vulnerability of CNS neurons does not correlate with the level of mitochondrial tRNAlys mutation in individual neuronal isolates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7746-53. PMID 9315896  0.48
1996 Chomyn A. Platelet-mediated transformation of human mitochondrial DNA-less cells. Methods in Enzymology. 264: 334-9. PMID 8965706 DOI: 10.1016/S0076-6879(96)64031-2  0.48
1996 Bentlage HA, Chomyn A. Immunoprecipitation of human mitochondrial translation products with peptide-specific antibodies. Methods in Enzymology. 264: 218-28. PMID 8965695 DOI: 10.1016/S0076-6879(96)64022-1  0.48
1996 Chomyn A. In vivo labeling and analysis of human mitochondrial translation products. Methods in Enzymology. 264: 197-211. PMID 8965693 DOI: 10.1016/S0076-6879(96)64020-8  0.48
1996 Ausenda C, Chomyn A. Purification of mitochondrial DNA from human cell cultures and placenta. Methods in Enzymology. 264: 122-8. PMID 8965686 DOI: 10.1016/S0076-6879(96)64013-0  0.48
1996 Shenkar R, Navidi W, Tavaré S, Dang MH, Chomyn A, Attardi G, Cortopassi G, Arnheim N. The mutation rate of the human mtDNA deletion mtDNA4977. American Journal of Human Genetics. 59: 772-80. PMID 8808591  0.48
1996 Hofhaus G, Johns DR, Hurko O, Attardi G, Chomyn A. Respiration and growth defects in transmitochondrial cell lines carrying the 11778 mutation associated with Leber's hereditary optic neuropathy. The Journal of Biological Chemistry. 271: 13155-61. PMID 8662757 DOI: 10.1074/Jbc.271.22.13155  0.48
1995 Mariottini P, Chomyn A. Immunoprecipitation of human NADH: ubiquinone oxidoreductase and cytochrome-c oxidase with single subunit-specific antibodies. Methods in Enzymology. 260: 202-10. PMID 8592445 DOI: 10.1016/0076-6879(95)60138-4  0.48
1995 Enriquez JA, Chomyn A, Attardi G. MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA(Lys) and premature translation termination. Nature Genetics. 10: 47-55. PMID 7647790 DOI: 10.1038/Ng0595-47  0.48
1995 Attardi G, Yoneda M, Chomyn A. Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems. Biochimica Et Biophysica Acta. 1271: 241-8. PMID 7599215 DOI: 10.1016/0925-4439(95)00034-2  0.48
1995 Bentlage HA, Janssen AJ, Chomyn A, Attardi G, Walker JE, Schägger H, Sengers RC, Trijbels FJ. Multiple deficiencies of mitochondrial DNA- and nuclear-encoded subunits of respiratory NADH dehydrogenase detected with peptide- and subunit-specific antibodies in mitochondrial myopathies. Biochimica Et Biophysica Acta. 1234: 63-73. PMID 7533543 DOI: 10.1016/0005-2736(94)00288-Z  0.48
1994 Chomyn A, Lai ST, Shakeley R, Bresolin N, Scarlato G, Attardi G. Platelet-mediated transformation of mtDNA-less human cells: analysis of phenotypic variability among clones from normal individuals--and complementation behavior of the tRNALys mutation causing myoclonic epilepsy and ragged red fibers. American Journal of Human Genetics. 54: 966-74. PMID 8198140  0.48
1994 Valberg SJ, Carlson GP, Cardinet GH, Birks EK, Jones JH, Chomyn A, DiMauro S. Skeletal muscle mitochondrial myopathy as a cause of exercise intolerance in a horse. Muscle & Nerve. 17: 305-12. PMID 8107707 DOI: 10.1002/Mus.880170308  0.48
1992 Chomyn A, Martinuzzi A, Yoneda M, Daga A, Hurko O, Johns D, Lai ST, Nonaka I, Angelini C, Attardi G. MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts. Proceedings of the National Academy of Sciences of the United States of America. 89: 4221-5. PMID 1584755 DOI: 10.1073/Pnas.89.10.4221  0.48
1992 Lewis W, Gonzalez B, Chomyn A, Papoian T. Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria. The Journal of Clinical Investigation. 89: 1354-60. PMID 1556193 DOI: 10.1172/JCI115722  0.48
1992 Yoneda M, Chomyn A, Martinuzzi A, Hurko O, Attardi G. Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 89: 11164-8. PMID 1454794 DOI: 10.1073/Pnas.89.23.11164  0.48
1992 Chomyn A, Attardi G. Chapter 20 Recent advances on mitochondrial biogenesis New Comprehensive Biochemistry. 23: 483-509. DOI: 10.1016/S0167-7306(08)60188-X  0.48
1991 Chomyn A, Meola G, Bresolin N, Lai ST, Scarlato G, Attardi G. In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria. Molecular and Cellular Biology. 11: 2236-44. PMID 1848674 DOI: 10.1128/Mcb.11.4.2236  0.48
1990 Attardi G, Chomyn A, King MP, Kruse B, Polosa PL, Murdter NN. Regulation of mitochondrial gene expression in mammalian cells. Biochemical Society Transactions. 18: 509-13. PMID 2276421 DOI: 10.1042/Bst0180509  0.48
1990 Bet L, Bresolin N, Moggio M, Meola G, Prelle A, Schapira AH, Binzoni T, Chomyn A, Fortunato F, Cerretelli P. A case of mitochondrial myopathy, lactic acidosis and complex I deficiency. Journal of Neurology. 237: 399-404. PMID 2125637 DOI: 10.1007/Bf00314729  0.48
1989 Chomyn A, Lai SS. cDNA of the 24 kDa subunit of the bovine respiratory chain NADH dehydrogenase: high sequence conservation in mammals and tissue-specific and growth-dependent expression. Current Genetics. 16: 117-26. PMID 2598272 DOI: 10.1007/Bf00393404  0.48
1988 Chomyn A, Patel SD, Cleeter MW, Ragan CI, Attardi G. The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of human NADH dehydrogenase. The Journal of Biological Chemistry. 263: 16395-400. PMID 3182798  0.48
1986 Chomyn A, Cleeter MW, Ragan CI, Riley M, Doolittle RF, Attardi G. URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit. Science (New York, N.Y.). 234: 614-8. PMID 3764430 DOI: 10.1126/Science.3764430  0.48
1986 Attardi G, Chomyn A, Doolittle RF, Mariottini P, Ragan CI. Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase. Cold Spring Harbor Symposia On Quantitative Biology. 51: 103-14. PMID 3472707 DOI: 10.1101/Sqb.1986.051.01.013  0.48
1986 Mariottini P, Chomyn A, Riley M, Cottrell B, Doolittle RF, Attardi G. Identification of the polypeptides encoded in the unassigned reading frames 2, 4, 4L, and 5 of human mitochondrial DNA. Proceedings of the National Academy of Sciences of the United States of America. 83: 1563-7. PMID 3456601 DOI: 10.1073/Pnas.83.6.1563  0.48
1986 Mariottini P, Chomyn A, Doolittle RF, Attardi G. Antibodies against the COOH-terminal undecapeptide of subunit II, but not those against the NH2-terminal decapeptide, immunoprecipitate the whole human cytochrome c oxidase complex. The Journal of Biological Chemistry. 261: 3355-62. PMID 2419330  0.48
1985 Chomyn A, Mariottini P, Cleeter MW, Ragan CI, Matsuno-Yagi A, Hatefi Y, Doolittle RF, Attardi G. Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase. Nature. 314: 592-7. PMID 3921850 DOI: 10.1038/314592A0  0.48
1983 Mariottini P, Chomyn A, Attardi G, Trovato D, Strong DD, Doolittle RF. Antibodies against synthetic peptides reveal that the unidentified reading frame A6L, overlapping the ATPase 6 gene, is expressed in human mitochondria. Cell. 32: 1269-77. PMID 6301689 DOI: 10.1016/0092-8674(83)90308-2  0.48
1983 Chomyn A, Mariottini P, Gonzalez-Cadavid N, Attardi G, Strong DD, Trovato D, Riley M, Doolittle RF. Identification of the polypeptides encoded in the ATPase 6 gene and in the unassigned reading frames 1 and 3 of human mtDNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 5535-9. PMID 6225122 DOI: 10.1073/Pnas.80.18.5535  0.48
1982 Attardi G, Chomyn A, Montoya J, Ojala D. Identification and mapping of human mitochondrial genes. Birth Defects Original Article Series. 18: 85-98. PMID 7159712  0.48
1982 Attardi G, Chomyn A, Montoya J, Ojala D. Identification and mapping of human mitochondrial genes. Cytogenetics and Cell Genetics. 32: 85-98. PMID 7140372 DOI: 10.1159/000131689  0.48
1982 Chomyn A, Mitchell HK. Synthesis of the 84,000 dalton protein in normal and heat shocked Drosophila melanogaster cells as detected by specific antibody Insect Biochemistry. 12: 105-114. DOI: 10.1016/0020-1790(82)90077-4  0.48
1981 Chomyn A, Hunkapiller MW, Attardi G. Alignment of the amino terminal amino acid sequence of human cytochrome c oxidase subunits I and II with the sequence of their putative mRNAs. Nucleic Acids Research. 9: 867-77. PMID 6262719 DOI: 10.1093/Nar/9.4.867  0.48
1979 Chomyn A, Moller G, Mitchell HK. Patterns of protein synthesis following heat shock in pupae of Drosophila melanogaster Developmental Genetics. 1: 77-95. DOI: 10.1002/Dvg.1020010109  0.48
Low-probability matches
2015 Chomyn A, Reichert A, Carroll L, Qureshi M, Toye J. 59: Low Socioeconomic Status and Very Preterm Birth: A “Double Jeopardy” in Child Language Development Paediatrics & Child Health. 20: e54-e55. DOI: 10.1093/PCH/20.5.E54A  0.01
2015 Bacman SR, Hashimoto M, Peralta S, Falk MJ, Chomyn A, Chan DC, Williams SL, Moraes CT. mitoTALENs as DNA editing tools for mitochondrial diseases Mitochondrion. 24: S22. DOI: 10.1016/J.Mito.2015.07.065  0.01
1996 Zhou L, Chomyn A, Attardi G, Miller CA. MERRF SYNDROME Journal of Neuropathology and Experimental Neurology. 55: 669. DOI: 10.1097/00005072-199605000-00265  0.01
1972 Chomyn A, Glusker JP, Berman HM, Carrell HL. The crystal structure of 10-chloromethyl-2,3,9-trimethylanthracene Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 28: 3512-3517. DOI: 10.1107/S0567740872008271  0.01
1997 Zhou L, Chomyn A, Attardi G, Miller CA. Myoclonic Epilepsy and Ragged Red Fibers (MERRF) Syndrome: Selective Vulnerability of CNS Neurons Does Not Correlate with the Level of Mitochondrial tRNAlys Mutation in Individual Neuronal Isolates The Journal of Neuroscience. 17: 7746-7753. DOI: 10.1523/Jneurosci.17-20-07746.1997  0
1982 Attardi G, Cantatore P, Chomyn A, Crews S, Gelfand R, Merkel C, Montoya J, Ojala D. A Comprehensive View of Mitochondrial Gene Expression in Human Cells Cold Spring Harbor Monograph Archive. 12: 51-71. DOI: 10.1101/087969145.12.51  0
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